CN111921430A

CN111921430A - Automatic homogenization kit

Info

Publication number: CN111921430A
Application number: CN202011019292.5A
Authority: CN
Inventors: 肖扬赟; 蔡志文; 董燕; 刘子龙; 刘银艳; 周华茂
Original assignee: Nanchang Maote Biotechnology Co ltd
Current assignee: Nanchang Maote Biotechnology Co ltd
Priority date: 2020-09-25
Filing date: 2020-09-25
Publication date: 2020-11-13
Anticipated expiration: 2040-09-25
Also published as: CN111921430B

Abstract

The invention discloses an automatic homogenization kit, relates to the technical field of reagent treatment devices for laboratories, and aims to solve the problems that a manual shaking mode is long in waiting time, a mechanical stirring mode needs to clean a mixing arm to avoid cross contamination between reagents, and a mixing efficiency cannot be completely ensured in an ultrasonic stirring mode. The top of box body is provided with the lid, the inside of box body is provided with the standing groove, the intermediate position department of standing groove is provided with the reagent frame, the intermediate position department of reagent frame one side is provided with first motor, the lower extreme of reagent frame has set gradually the test tube and has held the frame, the below that the test tube held the frame is provided with the second motor, the top of second motor is provided with the drive plate, the top of drive plate is fixed and is provided with first magnetic path and second magnetic path. The inside that the test tube held the frame is provided with the test tube, the inside of test tube is provided with the magnetic path.

Description

Automatic homogenization kit

Technical Field

The invention relates to a device or equipment for mixing and stirring reagents in a laboratory, in particular to an automatic homogenization kit.

Background

In the reaction of a diagnostic instrument, reagents easy to precipitate are required to be in a suspension state and evenly distributed when used, so that the reagent needles can obtain uniform quantity when sucked, and the reaction quality is ensured. The box is used for containing chemical reagents for detecting chemical components, drug residues, virus types and the like. The reagent box capable of homogenizing automatically has the function of mixing the reagents while meeting the storage requirement. Prior art documents to which this application may refer include:

patent numbers: CN205095720U, patent name: the kit, the kit component and the reagent mixing component are arranged in a container;

patent numbers: CN211358633U, patent name: a kit with shaking function;

patent numbers: CN106563380B, patent name: a kit with a stirring function;

patent numbers: CN108499410B, patent name: a stirrable kit.

The existing mixing method comprises the following steps: 1. the process generally needs half an hour in a manual shaking mode, and the waiting time is long; 2. the mechanical stirring mode, for example, the mixing rod is stirred under the liquid level of the magnetic bead box, a set of independent mixing arm capable of stretching and rotating is needed in the process, the structure needs to be cleaned to avoid cross contamination among reagents, a vibration table can be adopted for mixing, but the structure of the vibration table is complex, and errors are easy to occur in practical application; 3. ultrasonic wave stirring mode, this process need all carry out the mixing before using at every turn, and is consuming time, and can not ensure mixing efficiency completely, and the kit mixing time that can realize the mixing function simultaneously needs the manual work to set up comparatively inconveniently, therefore these problems are solved to the kit that urgently needs automatic homogenization on the market.

Disclosure of Invention

The invention aims to provide an automatic homogenization kit, which aims to solve the problems that the waiting time is long in the manual shaking mode in the background technology; in a mechanical stirring mode, the mixing arm needs to be cleaned to avoid cross contamination among reagents; the ultrasonic stirring mode can not ensure the mixing efficiency completely.

In order to achieve the purpose, the invention provides the following technical scheme: automatic homogenized kit, comprises a box bod, the top of box body is provided with the lid, the inside of box body is provided with the standing groove, the intermediate position department of standing groove is provided with reagent frame, the intermediate position department of reagent frame one side is provided with first motor, the lower extreme of reagent frame equidistance is provided with the test tube in proper order and holds the frame, the below that the test tube held the frame is provided with the second motor, the top of second motor is provided with the drive plate, the fixed first magnetic path and the second magnetic path that are provided with in top of drive plate, the inside that the test tube held the frame is provided with the test tube, the inside of test tube is provided with the magnetic path.

Preferably, the middle position department of reagent frame opposite side is provided with the swing pivot, and the swing pivot sets up with first motor relatively, the swing pivot respectively with box body and reagent frame fixed connection, the inside middle position department of lid is provided with the foam-rubber cushion, one side of foam-rubber cushion is provided with presses the briquetting, and presses briquetting and touch switch setting relatively.

Preferably, the bilateral symmetry of reagent frame is provided with limit baffle, pass through telescopic link fixed connection between limit baffle and the reagent frame, the both sides at reagent frame both ends all are provided with the telescopic link groove, and the one end of telescopic link is located the inside in telescopic link groove.

Preferably, the first magnetic block is located on one side of the second magnetic block, the first magnetic block and the second magnetic block are symmetrically arranged, and the first magnetic block and the second magnetic block are located below the test tube containing frame.

Preferably, the test tube lid is installed to the top of test tube, and the test tube lid passes through screw thread fixed connection with the test tube, the upper end of reagent frame is provided with the stopper, and the stopper is located the both sides of test tube upper end, the outside of test tube top is provided with the test tube and holds the frame lid, the inside that the test tube held the frame lid is provided with the electro-magnet.

Preferably, the test tube holds and laminates between the inboard of frame lid and the outside of test tube lid mutually, the electro-magnet is with the magnetic path actuation mutually.

Preferably, the top that test tube one end was kept away from to the stopper is provided with the lug, and lug and stopper structure as an organic whole, the test tube holds the inboard of frame cover lower extreme and is provided with the lug groove, and the one end of lug extends to the inside in lug groove.

Preferably, the below of first motor is provided with the timing module, the fixed time relay that is provided with of inner wall on one side of the box body, time relay and touch switch electric connection, time relay and the two-way electric connection of timing module, timing module and first motor, electro-magnet, telescopic link and second motor electric connection.

Compared with the prior art, the invention has the beneficial effects that:

1. according to the reagent rack, the first motor is arranged to drive the reagent rack to swing integrally, so that reagents in the test tube can be mixed more uniformly, the reagents can be mixed at the same time, the mixing efficiency is high, and meanwhile, the limiting baffle can limit the reagent during normal transportation, so that the reagents can be effectively protected. The problem that the waiting time is long in a manual shaking mode is solved; in a mechanical stirring mode, the mixing arm needs to be cleaned to avoid cross contamination among reagents; the ultrasonic stirring mode can not ensure the mixing efficiency completely.

2. According to the invention, the second motor is arranged to drive the first magnetic block and the second magnetic block to rotate, the magnetic blocks fall on the bottom of the test tube after the electromagnet is powered off, and the reagents are driven to carry out centrifugal mixing stirring in a mode of like-pole repulsion and opposite-pole attraction of the magnets, so that the number of foams in the reagents can be reduced while stirring, and the reagents can be conveniently used in the later period.

3. According to the reagent box, the touch switch is triggered when the reagent box is started through the arrangement of the touch switch and the time relay, the power supplies of the first motor and the second motor are switched on in a delayed mode through the time relay, a user can conveniently take out or put in reagents to be uniformly mixed in an early stage, and the time for uniformly mixing is controlled through the timing module.

Drawings

FIG. 1 is a top view of the present invention;

FIG. 2 is a cross-sectional view taken along the line A-A of the present invention;

FIG. 3 is an enlarged view of a portion of the area A according to the present invention;

FIG. 4 is a view showing the connection between the test tube accommodating cap and the test tube according to the present invention;

FIG. 5 is an enlarged view of a portion of the area B of the present invention;

FIG. 6 is a cross-sectional view of a reagent rack of the present invention.

In the figure: 1. a box body; 2. a box cover; 3. a placement groove; 4. a reagent rack; 5. a first motor; 6. swinging the rotating shaft; 7. a limit baffle; 8. a touch switch; 9. a pressing block; 10. a sponge cushion; 11. a timing module; 12. a time relay; 13. a second motor; 14. the test tube containing frame; 15. the test tube accommodating frame cover; 16. a drive plate; 17. a first magnetic block; 18. a second magnetic block; 19. an electromagnet; 20. a test tube; 21. a test tube cover; 22. a magnetic block; 23. a limiting block; 24. a bump groove; 25. a bump; 26. a telescopic rod groove; 27. a telescopic rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1-6, an embodiment of the present invention is shown: the automatic homogenization kit comprises a kit body 1, a kit cover 2 is arranged above the kit body 1, a placing groove 3 is arranged in the kit body 1, the placing groove 3 is used for placing a reagent rack 4, the reagent rack 4 is arranged in the middle of the placing groove 3 and is used for placing and driving a test tube 20, a first motor 5 is arranged in the middle of one side of the reagent rack 4 and is used for driving the reagent rack 4 to uniformly mix and swing, test tube containing frames 14 are sequentially arranged at the lower end of the reagent rack 4 at equal intervals and are used for supporting and limiting the test tube 20, a second motor 13 is arranged below the test tube containing frame 14 and is used for driving a first magnetic block 17 and a second magnetic block 18 to rotate, so that the magnetic block 22 is driven to rotate by a magnetic field, a driving plate 16 is arranged above the second motor 13 and is used for fixing the first magnetic block 17 and the second magnetic block 18, fixed first magnetic path 17 and the second magnetic path 18 of being provided with in top of drive plate 16, the inside that the test tube held frame 14 is provided with test tube 20, and test tube 20's inside is provided with magnetic path 22, and magnetic path 22's rotation drives reagent and carries out the centrifugation and rotate, has also reduced the bubble in the reagent when mixing to the demand of reagent follow-up use has been improved.

Further, the intermediate position department of 4 opposite sides of reagent frame is provided with swing pivot 6, swing pivot 6 provides spacing support for the drive of first motor 5, and swing pivot 6 sets up with first motor 5 relatively, swing pivot 6 respectively with box body 1 and 4 fixed connection of reagent frame, the inside intermediate position department of lid 2 is provided with foam-rubber cushion 10, foam-rubber cushion 10 is located the top of reagent frame 4, test tube 20 when transporting protects, one side of foam-rubber cushion 10 is provided with presses the briquetting 9, and press briquetting 9 and touch switch 8 and set up relatively, press briquetting 9 and realized pressing touch switch 8, just, the triggering of electric energy has been realized.

Further, reagent frame 4's bilateral symmetry is provided with limit baffle 7, and limit baffle 7's extension has just realized the spacing to reagent frame 4, through telescopic link 27 fixed connection between limit baffle 7 and the reagent frame 4, and telescopic link 27 drives limit baffle 7 and moves to control reagent frame 4 and move. Both sides at reagent frame 4 both ends all are provided with telescopic link groove 26, and the one end of telescopic link 27 is located telescopic link groove 26's inside, and telescopic link groove 26 provides the space for telescopic link 27's setting.

Further, the first magnetic block 17 is located on one side of the second magnetic block 18, the first magnetic block 17 and the second magnetic block 18 are symmetrically arranged, the first magnetic block 17 and the second magnetic block 18 are located below the test tube containing frame 14, the upward surfaces of the first magnetic block 17 and the second magnetic block 18 are of repulsive magnetism, and the magnetism is distributed more uniformly through the opposite arrangement.

Further, test tube lid 21 is installed to test tube 20's top, and test tube lid 21 passes through screw thread fixed connection with test tube 20, the upper end of reagent frame 4 is provided with stopper 23, stopper 23 is spacing to test tube 20's upper end, and stopper 23 is located the both sides of test tube 20 upper end, the outside of test tube 20 top is provided with the test tube and holds framed cover 15, the test tube holds framed cover 15 and carries on spacingly to test tube 20's upper end, the inside that the test tube held framed cover 15 is provided with electro-magnet 19, electro-magnet 19 has realized the injectment to the magnetic path 22 position.

Further, the test tube holds laminating mutually between the inboard of protecgulum 15 and the outside of protecgulum 21, and electro-magnet 19 and the actuation of magnetic path 22 mutually let the test tube hold protecgulum 15 carry on spacingly to protecgulum 21 through the laminating setting, the test tube 20 of fine protection mixing, the actuation setting carries on effectually spacingly to magnetic path 22.

Further, stopper 23 is provided with lug 25 in the top of keeping away from test tube 20 one end, and lug 25 and stopper 23 structure as an organic whole, and the test tube holds the inboard of protecgulum 15 lower extreme and is provided with lug groove 24, and the one end of lug 25 extends to the inside of lug groove 24, and lug 25 and lug groove 24's cooperation has realized holding the spacing of protecgulum 15 to the test tube.

Further, the below of first motor 5 is provided with timing module 11, timing module 11 can take notes and adjust the mixing time, the fixed time relay 12 that is provided with of inner wall on one side of the box body 1, time relay 12 can prolong the triggering time of electric energy, time relay 12 and touch switch 8 electric connection, time relay 12 and the two-way electric connection of timing module 11, timing module 11 and first motor 5, electro-magnet 19, telescopic link 27 and second motor 13 electric connection, circuit control of each part has been realized through electric connection.

The working principle is as follows: when the reagent box is used, a worker opens the box cover 2, the pressing block 9 on the box cover 2 releases the pressing on the touch switch 8, so that the circuit is connected, the time relay 12 performs delay control on the transmission of electric energy, the worker can take away or add test tubes according to the requirement, the telescopic rod 27 can contract at the same time, the limiting baffle 7 approaches the reagent box 4 to contact the limiting baffle 7 to limit the reagent box, when the time relay 12 sets the time, the first motor 5 is opened to drive the reagent box 4 to swing back and forth, so that the reagent is uniformly mixed, the timing module records the time, when the swinging time is up, the power supply of the first motor 5 is disconnected, the limiting baffle 7 is pushed out to be attached to the box body 1 by extending the telescopic rod 27, so that the reagent box is limited, and the power supply of the electromagnet 19 is disconnected, magnetic path 22 does not receive electromagnet 19 magnetic attraction spacing just can fall down, the second motor 13 of opening this moment drives first magnetic path 17 and second magnetic path 18 and rotates, alright drive magnetic path 22 rotates because magnetic field, thereby carry out centrifugal stirring to reagent, the bubble in the reagent has been reduced simultaneously to mixing efficiency has been improved, can let mixing efficiency higher through the combination of two kinds of mixing modes, touch switch 8's setting has realized automatic mixing effect simultaneously, and limit baffle 7's setting alright improves reagent frame 4's stability.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. Automatic homogenization's kit includes box body (1), its characterized in that: the utility model discloses a test tube storage box, including box body (1), box cover (2), the inside of box body (1) is provided with standing groove (3), the intermediate position department of standing groove (3) is provided with reagent frame (4), the intermediate position department of reagent frame (4) one side is provided with first motor (5), the lower extreme of reagent frame (4) has set gradually the test tube in the equidistance and has held frame (14), the below that the test tube held frame (14) is provided with second motor (13), the top of second motor (13) is provided with drive plate (16), the fixed first magnetic path (17) and the second magnetic path (18) that are provided with in top of drive plate (16), the inside that the test tube held frame (14) is provided with test tube (20), the inside of test tube (20) is provided with magnetic path (22).

2. The kit for automated homogenization according to claim 1, wherein: reagent frame (4) opposite side intermediate position department is provided with swing pivot (6), and swing pivot (6) and first motor (5) set up relatively, swing pivot (6) respectively with box body (1) and reagent frame (4) fixed connection, lid (2) inside intermediate position department is provided with foam-rubber cushion (10), one side of foam-rubber cushion (10) is provided with presses button (9), and presses button (9) and touch switch (8) and set up relatively.

3. The kit for automated homogenization according to claim 1, wherein: the bilateral symmetry of reagent frame (4) is provided with limit baffle (7), pass through telescopic link (27) fixed connection between limit baffle (7) and reagent frame (4), the both sides at reagent frame (4) both ends all are provided with telescopic link groove (26), and the one end of telescopic link (27) is located the inside in telescopic link groove (26).

4. The kit for automated homogenization according to claim 1, wherein: the first magnetic block (17) is located on one side of the second magnetic block (18), the first magnetic block (17) and the second magnetic block (18) are symmetrically arranged, and the first magnetic block (17) and the second magnetic block (18) are located below the test tube containing frame (14).

5. The kit for automated homogenization according to claim 1, wherein: test tube lid (21) is installed to the top of test tube (20), and test tube lid (21) passes through screw thread fixed connection with test tube (20), the upper end of reagent frame (4) is provided with stopper (23), and stopper (23) are located the both sides of test tube (20) upper end, the outside of test tube (20) top is provided with the test tube and holds frame cover (15), the inside that the test tube held frame cover (15) is provided with electro-magnet (19).

6. The kit for automated homogenization according to claim 5, wherein: the inner side of the test tube containing frame cover (15) is attached to the outer side of the test tube cover (21), and the electromagnet (19) is attracted to the magnetic block (22).

7. The kit for automated homogenization according to claim 5, wherein: stopper (23) are kept away from the top of test tube (20) one end and are provided with lug (25), and lug (25) and stopper (23) structure as an organic whole, the test tube holds the inboard of frame lid (15) lower extreme and is provided with lug groove (24), and the one end of lug (25) extends to the inside in lug groove (24).

8. The kit for automated homogenization according to claim 1, wherein: the utility model discloses a timing module, including box body (1), time relay (12) and touch switch (8), time relay (12) and timing module (11) two-way electric connection, timing module (11) and first motor (5), electro-magnet (19), telescopic link (27) and second motor (13) electric connection.