CN111920687A - Powder formula 3D medicine printer - Google Patents
Powder formula 3D medicine printer Download PDFInfo
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- CN111920687A CN111920687A CN202010883425.7A CN202010883425A CN111920687A CN 111920687 A CN111920687 A CN 111920687A CN 202010883425 A CN202010883425 A CN 202010883425A CN 111920687 A CN111920687 A CN 111920687A
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- 239000003814 drug Substances 0.000 title claims abstract description 28
- 235000020610 powder formula Nutrition 0.000 title claims description 3
- 238000003860 storage Methods 0.000 claims abstract description 75
- 238000002156 mixing Methods 0.000 claims abstract description 51
- 239000002994 raw material Substances 0.000 claims abstract description 49
- 239000000203 mixture Substances 0.000 claims abstract description 48
- 230000001105 regulatory effect Effects 0.000 claims abstract description 35
- 238000007639 printing Methods 0.000 claims abstract description 34
- 238000007599 discharging Methods 0.000 claims abstract description 28
- 238000001125 extrusion Methods 0.000 claims abstract description 22
- 239000000463 material Substances 0.000 claims abstract description 16
- 230000003287 optical effect Effects 0.000 claims description 52
- 230000005540 biological transmission Effects 0.000 claims description 40
- 230000002457 bidirectional effect Effects 0.000 claims description 39
- 230000007246 mechanism Effects 0.000 claims description 34
- 230000001360 synchronised effect Effects 0.000 claims description 28
- 229940079593 drug Drugs 0.000 claims description 13
- 230000033001 locomotion Effects 0.000 claims description 7
- 230000008878 coupling Effects 0.000 claims description 5
- 238000010168 coupling process Methods 0.000 claims description 5
- 238000005859 coupling reaction Methods 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 4
- 238000005192 partition Methods 0.000 claims description 4
- 239000000843 powder Substances 0.000 abstract description 7
- 238000010438 heat treatment Methods 0.000 description 5
- 230000009471 action Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000010146 3D printing Methods 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y40/00—Auxiliary operations or equipment, e.g. for material handling
- B33Y40/10—Pre-treatment
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y70/00—Materials specially adapted for additive manufacturing
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- Manufacturing & Machinery (AREA)
- Materials Engineering (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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Abstract
A powder type 3D medicine printer comprises a rack, a quantitative feeding module, a mixing and conveying module and a forming and printing module; the quantitative feeding module, the mixing and conveying module and the forming and printing module are distributed on the rack from top to bottom; the quantitative feeding module comprises a quantitative feeding module support, a material storage groove, a raw material scattering blade, a raw material scattering motor, a quantitative material storage barrel, a storage barrel overturning sleeve, an overturning sleeve driving motor, a fixed limiting sleeve, a pressure regulating piston and a pressure regulating piston driving motor; the mixing and conveying module comprises a mixing and conveying module bracket, a mixing hopper, a mixture discharging channel, a mixture discharging check valve, a check valve driving motor and a mixture screw conveyer; the forming printing module comprises a platform hot bed, a screw extrusion type printing head, a horizontal position adjusting assembly and a vertical position adjusting assembly. The raw materials can be mixed in a printer in a personalized ratio, and the mixture can be printed into a required shape and size after being mixed in the ratio, so that personalized customization of the medicine is realized.
Description
Technical Field
The invention belongs to the technical field of 3D printing of medicines, and particularly relates to a powder type 3D medicine printer.
Background
3D printing is used as an additive manufacturing technology in more and more fields, but the application in the field of medical pharmacy is still in the initial stage, particularly, the preparation of medicines rarely can be different from person to person, the medicines taken by most patients are generally the medicines manufactured in a standardized way, the difference of taking medicines is only reflected in the difference of the taking dosage of the medicines when following the medical advice, and the difference of the components of the medicines is difficult to achieve.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a powder type 3D medicine printer, medicine raw materials can be subjected to personalized proportioning in the printer, the proportioned medicine raw materials can be printed into a required shape and size according to design requirements after being mixed, and finally personalized customization of medicines is realized.
In order to achieve the purpose, the invention adopts the following technical scheme: a powder type 3D medicine printer comprises a rack, a quantitative feeding module, a mixing and conveying module and a forming and printing module; the quantitative feeding module, the mixing conveying module and the forming printing module are distributed on the rack from top to bottom, the discharge end of the quantitative feeding module is communicated with the feed end of the mixing conveying module, and the discharge end of the mixing conveying module is communicated with the feed end of the forming printing module.
The quantitative feeding module comprises a quantitative feeding module support, a material storage groove, a raw material scattering blade, a raw material scattering motor, a quantitative material storage barrel, a material storage barrel overturning sleeve, an overturning sleeve driving motor, a fixed limiting sleeve, a pressure regulating piston and a pressure regulating piston driving motor; the quantitative feeding module support is fixedly arranged on the rack, the storage tank is vertically and fixedly arranged at the top of the quantitative feeding module support, the raw material scattering blade is positioned in the storage tank, the raw material scattering motor is positioned outside the storage tank, a central shaft of the raw material scattering blade extends to the outside of the storage tank, and the central shaft of the raw material scattering blade is fixedly connected with a motor shaft of the raw material scattering motor through a coupling; the fixed limiting sleeve is of a cylindrical structure and is horizontally and fixedly arranged below the storage tank, a feed inlet is formed in the upper cylinder wall of the fixed limiting sleeve, a discharge outlet is formed in the lower cylinder wall of the fixed limiting sleeve, and the feed inlet of the fixed limiting sleeve is communicated with the discharge outlet below the storage tank; the quantitative storage cylinder is fixedly arranged on the side cylinder wall of the storage cylinder overturning sleeve along the radial direction, a cylinder opening at one end of the quantitative storage cylinder is of an open structure, and a cylinder opening at the other end of the quantitative storage cylinder is sealed by an outer cover of a ventilating partition plate; the overturning sleeve driving motor is positioned outside the fixed limiting sleeve, the central shaft of the storage barrel overturning sleeve extends to the outside of the fixed limiting sleeve, and the central shaft of the storage barrel overturning sleeve is fixedly connected with the motor shaft of the overturning sleeve driving motor through a coupler; the pressure regulating piston is coaxially arranged on the inner side of the storage cylinder overturning sleeve, the pressure regulating piston has a linear movement degree of freedom relative to the storage cylinder overturning sleeve, and meanwhile, the storage cylinder overturning sleeve has a rotary degree of freedom relative to the pressure regulating piston; the piston rod of the pressure regulating piston extends to the outer side of the fixed limiting sleeve, the pressure regulating piston driving motor is located on the outer side of the fixed limiting sleeve, and a motor shaft of the pressure regulating piston driving motor is in transmission connection with the piston rod of the pressure regulating piston through a crank-link mechanism.
The mixing and conveying module comprises a mixing and conveying module bracket, a mixing hopper, a mixture discharging channel, a mixture discharging check valve, a check valve driving motor and a mixture screw conveyer; the mixing hopper is vertically and fixedly arranged under the discharge port of the fixed limiting sleeve, the discharge end of the mixing hopper is communicated with the feed port of the mixture discharge channel, the discharge port of the mixture discharge channel is communicated with the feed port of the mixture screw conveyor, the mixture screw conveyor is vertically arranged on the mixing conveying module support, and the discharge port of the mixture screw conveyor faces downwards; the mixture discharging check valve is arranged at the discharge port of the mixing hopper, the valve spool of the mixture discharging check valve extends to the outer side of the mixing hopper, the check valve driving motor is horizontally and fixedly arranged on the mixing conveying module support, and the motor shaft of the check valve driving motor is fixedly connected with the valve spool of the mixture discharging check valve through a coupling.
The molding printing module comprises a platform hot bed, a screw extrusion type printing head, a horizontal position adjusting assembly and a vertical position adjusting assembly; the horizontal position adjusting assembly comprises an X-direction guide optical axis, an X-direction sliding block, a Y-direction guide optical axis, a Y-direction sliding block, a first XY bidirectional adjusting driving motor, a first XY bidirectional synchronous belt transmission mechanism, a second XY bidirectional adjusting driving motor, a second XY bidirectional synchronous belt transmission mechanism, a Z-direction lead screw, a Z-direction screw nut, a Z-direction guide optical axis, a Z-direction sliding sleeve, a Z-direction supporting frame, a Z-direction adjusting driving motor and a Z-direction synchronous belt transmission mechanism; the X-direction guide optical axes adopt a parallel double-shaft structure, the X-direction guide optical axes are horizontally and fixedly arranged on the rack, X-direction sliders are arranged on the two X-direction guide optical axes and can move linearly along the X-direction guide optical axes; the Y-direction guide optical axis is horizontally and fixedly arranged on the X-direction sliding block, the Y-direction guide optical axis adopts a parallel double-shaft structure, the Y-direction sliding block is arranged on the Y-direction guide optical axis, and the Y-direction sliding block can move linearly along the Y-direction guide optical axis; the first XY bidirectional adjusting driving motor is vertically and fixedly arranged on the rack, and is in transmission connection with the X-direction sliding block and the Y-direction sliding block through a first XY bidirectional synchronous belt transmission mechanism; the second XY bidirectional adjusting driving motor is vertically and fixedly arranged on the rack, and is in transmission connection with the X-direction sliding block and the Y-direction sliding block through a second XY bidirectional synchronous belt transmission mechanism; the first XY bidirectional synchronous belt transmission mechanism and the second XY bidirectional synchronous belt transmission mechanism are distributed in mirror symmetry with each other; the Z-direction lead screw is vertically arranged on the rack and has a rotation degree of freedom; the Z-direction guide optical axis adopts a parallel double-shaft structure, the Z-direction guide optical axis is vertically and fixedly arranged on the rack, and the Z-direction lead screw is positioned between the two Z-direction guide optical axes; the Z-direction screw nut is arranged on the Z-direction screw rod, the Z-direction sliding sleeve is arranged on the Z-direction guide optical axis, and the Z-direction supporting frame is fixedly connected between the Z-direction screw nut and the Z-direction sliding sleeve; the platform hot bed is horizontally and fixedly arranged on the Z-direction supporting frame; the Z-direction adjusting driving motor is vertically and fixedly arranged at the bottom of the rack, and is in transmission connection with the Z-direction lead screw through a Z-direction synchronous belt transmission mechanism; the screw extrusion type printing head is vertically and fixedly arranged on the Y-direction sliding block, and a feeding port of the screw extrusion type printing head is communicated with a discharging port of the mixture screw conveyor through a hose; and a heater is arranged on a discharge pipe of the screw extrusion type printing head, and a temperature sensor is arranged in the heater.
The invention has the beneficial effects that:
according to the powder type 3D medicine printer, medicine raw materials can be subjected to personalized proportioning in the printer, the proportioned medicine raw materials can be printed into a required shape and size according to design requirements after being mixed, and personalized customization of medicines is finally achieved.
Drawings
FIG. 1 is a schematic structural diagram of a powder type 3D medication printer according to the present invention;
FIG. 2 is a perspective view of the dosing module and compounding delivery module of the present invention as assembled;
FIG. 3 is a plan cross-sectional view of the dosing module of the present invention as fitted with a compounding conveyor module;
FIG. 4 is an enlarged view of section I of FIG. 3 (with the dosing cartridge in a charged state);
FIG. 5 is a diagram showing the effect of the magazine flip sleeve of FIG. 4 after rotation through 180 ° (with the dosing magazine in the discharge position);
FIG. 6 is a schematic structural view of a profiled printing module of the present invention;
FIG. 7 is a schematic structural diagram of a screw extrusion printhead according to the present invention;
in the figure, 1-frame, 2-dosing module support, 3-material storage tank, 4-material scattering blade, 5-material scattering motor, 6-dosing storage cylinder, 7-storage cylinder turning sleeve, 8-turning sleeve driving motor, 9-fixed limit sleeve, 10-pressure regulating piston, 11-pressure regulating piston driving motor, 12-air permeable partition housing, 13-crank link mechanism, 14-material mixing and conveying module support, 15-material mixing hopper, 16-material discharging channel, 17-material discharging check valve, 18-check valve driving motor, 19-material mixing screw conveyor, 20-platform hot bed, 21-screw extrusion type printing head, 22-X-direction guide optical axis, 23-X-direction slide block, 24-Y-direction guide optical axis, 25-Y-direction slide block, 26-first XY two-way adjusting driving motor, 27-first XY two-way synchronous belt transmission mechanism, 28-second XY two-way adjusting driving motor, 29-a second XY bidirectional synchronous belt transmission mechanism, 30-a Z-direction lead screw, 31-a Z-direction nut, 32-a Z-direction guide optical axis, 33-a Z-direction sliding sleeve, 34-a supporting frame, 35-a Z-direction adjusting driving motor, 36-a Z-direction synchronous belt transmission mechanism, 37-a hose and 38-a heater.
Detailed Description
The invention is described in further detail below with reference to the figures and the specific embodiments.
As shown in fig. 1 to 7, a powder type 3D medicine printer includes a frame 1, a dosing module, a mixing and conveying module, and a molding and printing module; the dosing module, the mixing conveying module and the forming printing module are distributed on the rack 1 from top to bottom, the discharge end of the dosing module is communicated with the feed end of the mixing conveying module, and the discharge end of the mixing conveying module is communicated with the feed end of the forming printing module.
The quantitative feeding module comprises a quantitative feeding module support 2, a storage tank 3, a raw material scattering blade 4, a raw material scattering motor 5, a quantitative storage cylinder 6, a storage cylinder overturning sleeve 7, an overturning sleeve driving motor 8, a fixed limiting sleeve 9, a pressure regulating piston 10 and a pressure regulating piston driving motor 11; the quantitative feeding module support 2 is fixedly arranged on the frame 1, the storage tank 3 is vertically and fixedly arranged at the top of the quantitative feeding module support 2, the raw material scattering blade 4 is positioned in the storage tank 3, the raw material scattering motor 5 is positioned outside the storage tank 3, the central shaft of the raw material scattering blade 4 extends to the outside of the storage tank 3, and the central shaft of the raw material scattering blade 4 is fixedly connected with the motor shaft of the raw material scattering motor 5 through a coupling; the fixed limiting sleeve 9 is of a cylindrical structure, the fixed limiting sleeve 9 is horizontally and fixedly arranged below the storage tank 3, a feed inlet is formed in the upper cylinder wall of the fixed limiting sleeve 9, a discharge outlet is formed in the lower cylinder wall of the fixed limiting sleeve 9, and the feed inlet of the fixed limiting sleeve 9 is communicated with the discharge outlet below the storage tank 3; the storage cylinder overturning sleeve 7 is coaxially sleeved on the inner side of the fixed limiting sleeve 9, the storage cylinder overturning sleeve 7 has a rotation degree of freedom relative to the fixed limiting sleeve 9, the quantitative storage cylinder 6 is fixedly installed on the side cylinder wall of the storage cylinder overturning sleeve 7 along the radial direction, a cylinder opening at one end of the quantitative storage cylinder 6 is of an open structure, and a cylinder opening at the other end of the quantitative storage cylinder 6 is blocked by the air-permeable partition plate outer cover 12; the overturning sleeve driving motor 8 is positioned outside the fixed limiting sleeve 9, the central shaft of the storage cylinder overturning sleeve 7 extends to the outside of the fixed limiting sleeve 9, and the central shaft of the storage cylinder overturning sleeve 7 is fixedly connected with the motor shaft of the overturning sleeve driving motor 8 through a coupler; the pressure regulating piston 10 is coaxially arranged on the inner side of the storage cylinder overturning sleeve 7, the pressure regulating piston 10 has a linear movement degree of freedom relative to the storage cylinder overturning sleeve 7, and meanwhile, the storage cylinder overturning sleeve 7 has a rotary degree of freedom relative to the pressure regulating piston 10; the piston rod of the pressure regulating piston 10 extends to the outer side of the fixed limiting sleeve 9, the pressure regulating piston driving motor 11 is located on the outer side of the fixed limiting sleeve 9, and a motor shaft of the pressure regulating piston driving motor 11 is in transmission connection with the piston rod of the pressure regulating piston 10 through a crank connecting rod mechanism 13.
The mixing and conveying module comprises a mixing and conveying module support 14, a mixing hopper 15, a mixture discharging channel 16, a mixture discharging check valve 17, a check valve driving motor 18 and a mixture screw conveyor 19; the mixing hopper 15 is vertically and fixedly arranged right below a discharge hole of the fixed limiting sleeve 9, the discharge end of the mixing hopper 15 is communicated with a feed hole of the mixture discharge channel 16, the discharge hole of the mixture discharge channel 16 is communicated with a feed hole of the mixture screw conveyor 19, the mixture screw conveyor 19 is vertically arranged on the mixing conveying module support 14, and the discharge hole of the mixture screw conveyor 19 faces downwards; the mixture discharging check valve 17 is arranged at the discharging port of the mixing hopper 15, the valve core shaft of the mixture discharging check valve 17 extends to the outer side of the mixing hopper 15, the check valve driving motor 18 is horizontally and fixedly arranged on the mixing conveying module support 14, and the motor shaft of the check valve driving motor 18 is fixedly connected with the valve core shaft of the mixture discharging check valve 17 through a coupler.
The molding printing module comprises a platform hot bed 20, a screw extrusion type printing head 21, a horizontal position adjusting assembly and a vertical position adjusting assembly; the horizontal position adjusting component comprises an X-direction guide optical axis 22, an X-direction sliding block 23, a Y-direction guide optical axis 24, a Y-direction sliding block 25, a first XY bidirectional adjusting driving motor 26, a first XY bidirectional synchronous belt transmission mechanism 27, a second XY bidirectional adjusting driving motor 28, a second XY bidirectional synchronous belt transmission mechanism 29, a Z-direction lead screw 30, a Z-direction screw nut 31, a Z-direction guide optical axis 32, a Z-direction sliding sleeve 33, a Z-direction supporting frame 34, a Z-direction adjusting driving motor 35 and a Z-direction synchronous belt transmission mechanism 36; the X-direction guide optical axis 22 adopts a parallel double-shaft structure, the X-direction guide optical axis 22 is horizontally and fixedly arranged on the rack 1, X-direction sliders 23 are arranged on the two X-direction guide optical axes 22, and the X-direction sliders 23 can move linearly along the X-direction guide optical axis 22; the Y-direction guide optical axis 24 is horizontally and fixedly arranged on the X-direction sliding block 23, the Y-direction guide optical axis 24 adopts a parallel double-shaft structure, the Y-direction sliding block 25 is arranged on the Y-direction guide optical axis 24, and the Y-direction sliding block 25 can linearly move along the Y-direction guide optical axis 24; the first XY bidirectional adjusting driving motor 26 is vertically and fixedly arranged on the rack 1, and the first XY bidirectional adjusting driving motor 26 is in transmission connection with the X-direction sliding block 23 and the Y-direction sliding block 25 through a first XY bidirectional synchronous belt transmission mechanism 27; the second XY bidirectional adjusting driving motor 28 is vertically and fixedly arranged on the rack 1, and the second XY bidirectional adjusting driving motor 28 is in transmission connection with the X-direction sliding block 23 and the Y-direction sliding block 25 through a second XY bidirectional synchronous belt transmission mechanism 29; the first XY bidirectional synchronous belt transmission mechanism 27 and the second XY bidirectional synchronous belt transmission mechanism 29 are distributed in mirror symmetry with each other; the Z-direction lead screw 30 is vertically arranged on the rack 1, and the Z-direction lead screw 30 has a rotation degree of freedom; the Z-direction guide optical axis 31 adopts a parallel double-shaft structure, the Z-direction guide optical axis 31 is vertically and fixedly arranged on the rack 1, and the Z-direction lead screw 30 is positioned between the two Z-direction guide optical axes 31; the Z-direction screw nut 31 is arranged on the Z-direction screw rod 30, the Z-direction sliding sleeve 33 is arranged on the Z-direction guide optical axis 31, and the Z-direction supporting frame 34 is fixedly connected between the Z-direction screw nut 31 and the Z-direction sliding sleeve 33; the platform heating bed 20 is horizontally and fixedly arranged on a Z-direction supporting frame 34; the Z-direction adjusting driving motor 35 is vertically and fixedly arranged at the bottom of the rack 1, and the Z-direction adjusting driving motor 35 is in transmission connection with the Z-direction lead screw 30 through a Z-direction synchronous belt transmission mechanism 36; the screw extrusion type printing head 21 is vertically and fixedly arranged on the Y-direction sliding block 25, and a feeding hole of the screw extrusion type printing head 21 is communicated with a discharging hole of the mixture screw conveyor 19 through a hose 37; a heater 38 is attached to a discharge pipe of the screw extrusion head 21, and a temperature sensor is incorporated in the heater 38.
The one-time use process of the present invention is described below with reference to the accompanying drawings:
in this embodiment, two dosing modules are used as a simple example, the raw material a is poured into the storage tank 3 in the first dosing module, the raw material B is poured into the storage tank 3 in the second dosing module, then the raw material scattering motor 5 is started, the raw material scattering blade 4 is driven to rotate, the raw material stored in the storage tank 3 is scattered and stirred, the raw material can uniformly fall into the lower dosing storage cylinder 6, the pressure regulating piston driving motor 11 is started at the same time, the pressure regulating piston 10 is driven to move outwards through the crank-link mechanism 13, so that negative pressure is generated inside the storage cylinder turnover sleeve 7, at the moment, redundant air mixed in the dosing storage cylinder 6 can be discharged, the raw material in the dosing storage cylinder 6 is more compactly filled, and the accuracy of the raw material filling amount can be ensured.
After the raw material filling of the quantitative storage cylinder 6 is completed, the overturning sleeve driving motor 8 is started, the storage cylinder overturning sleeve 7 is controlled to rotate 180 degrees, the cylinder opening of the quantitative storage cylinder 6 is changed to be vertical downwards, then the pressure regulating piston driving motor 11 is started again, the pressure regulating piston 10 is driven to move inwards through the crank link mechanism 13, so that positive pressure is generated inside the storage cylinder overturning sleeve 7, at the moment, the raw material filled in the quantitative storage cylinder 6 is discharged out of the quantitative storage cylinder 6 under the pushing action of air pressure and directly falls into the mixing hopper 15 below, at the moment, the raw material A and the raw material B are preliminarily mixed in the mixing hopper 15, the preliminarily mixed raw material is blocked by the mixture discharging check valve 17, then the check valve driving motor 18 is started, the mixture discharging check valve 17 is controlled to be opened, and the preliminarily mixed raw material flows into the mixture screw conveyor 19 along the mixture discharging channel 16, and when all the raw materials in the mixing hopper 15 fall down, the mixture discharging check valve 17 is controlled to be closed.
Starting the mixture screw conveyor 19, deeply mixing the two raw materials under the spiral conveying action, when the raw materials are discharged from the mixture screw conveyor 19 and enter the hose 37, indicating that the raw materials are fully mixed, continuously discharging the raw materials from the mixture screw conveyor 19, and under the action of a top thrust, directly entering the screw extrusion type printing head 21 along the hose 37, and starting the screw extrusion type printing head 21 and the heater 38 until the raw materials reaching the set temperature flow out from a discharge port at the bottom of the screw extrusion type printing head 21.
After the screw extrusion type printing head 21 outputs the raw material with the set temperature, according to a pre-programmed printing program, a first XY bidirectional adjustment driving motor 26 and a second XY bidirectional adjustment driving motor 28 provide a horizontal movement driving force for the screw extrusion type printing head 21, and a Z-direction adjustment driving motor 35 provides a vertical movement driving force for the platform heating bed 20, so that three-degree-of-freedom linkage of the 3D printer is realized, and finally, a medicine with the shape and the size completely meeting the personalized customization requirements is formed on the platform heating bed 20; specifically, when the screw extrusion printhead 21 needs to move in the X direction, only the first XY bidirectional adjustment driving motor 26 and the second XY bidirectional adjustment driving motor 28 need to be controlled to rotate in reverse and synchronously, at this time, the degree of freedom of the Y-directional slider 25 on the Y-directional optical axis 24 is limited, and at the same time, the X-directional slider 23 can move along the X-directional optical axis 22; on the contrary, when the screw extrusion printhead 21 needs to move in the Y direction, only the first XY bidirectional adjustment driving motor 26 and the second XY bidirectional adjustment driving motor 28 need to be controlled to synchronously rotate in the same direction, at this time, the degree of freedom of the X-direction slider 23 on the X-direction guide optical axis 22 is limited, and the Y-direction slider 25 can move along the Y-direction guide optical axis 24; when the height of the platform heating bed 20 needs to be adjusted along the Z direction, the Z direction adjustment driving motor 35 is started, the Z direction synchronous belt transmission mechanism 36 drives the Z direction lead screw 30 to rotate, the rotation of the Z direction lead screw 30 can convert the rotation motion into the linear motion of the Z direction screw 31, and the Z direction screw 31 drives the Z direction support frame 34 and the platform heating bed 20 to synchronously move in the vertical direction.
The embodiments are not intended to limit the scope of the present invention, and all equivalent implementations or modifications without departing from the scope of the present invention are intended to be included in the scope of the present invention.
Claims (4)
1. The utility model provides a powder formula 3D medicine printer which characterized in that: the automatic feeding device comprises a rack, a quantitative feeding module, a mixing and conveying module and a forming and printing module; the quantitative feeding module, the mixing conveying module and the forming printing module are distributed on the rack from top to bottom, the discharge end of the quantitative feeding module is communicated with the feed end of the mixing conveying module, and the discharge end of the mixing conveying module is communicated with the feed end of the forming printing module.
2. The powdered 3D medication printer of claim 1, wherein: the quantitative feeding module comprises a quantitative feeding module support, a material storage groove, a raw material scattering blade, a raw material scattering motor, a quantitative material storage barrel, a material storage barrel overturning sleeve, an overturning sleeve driving motor, a fixed limiting sleeve, a pressure regulating piston and a pressure regulating piston driving motor; the quantitative feeding module support is fixedly arranged on the rack, the storage tank is vertically and fixedly arranged at the top of the quantitative feeding module support, the raw material scattering blade is positioned in the storage tank, the raw material scattering motor is positioned outside the storage tank, a central shaft of the raw material scattering blade extends to the outside of the storage tank, and the central shaft of the raw material scattering blade is fixedly connected with a motor shaft of the raw material scattering motor through a coupling; the fixed limiting sleeve is of a cylindrical structure and is horizontally and fixedly arranged below the storage tank, a feed inlet is formed in the upper cylinder wall of the fixed limiting sleeve, a discharge outlet is formed in the lower cylinder wall of the fixed limiting sleeve, and the feed inlet of the fixed limiting sleeve is communicated with the discharge outlet below the storage tank; the quantitative storage cylinder is fixedly arranged on the side cylinder wall of the storage cylinder overturning sleeve along the radial direction, a cylinder opening at one end of the quantitative storage cylinder is of an open structure, and a cylinder opening at the other end of the quantitative storage cylinder is sealed by an outer cover of a ventilating partition plate; the overturning sleeve driving motor is positioned outside the fixed limiting sleeve, the central shaft of the storage barrel overturning sleeve extends to the outside of the fixed limiting sleeve, and the central shaft of the storage barrel overturning sleeve is fixedly connected with the motor shaft of the overturning sleeve driving motor through a coupler; the pressure regulating piston is coaxially arranged on the inner side of the storage cylinder overturning sleeve, the pressure regulating piston has a linear movement degree of freedom relative to the storage cylinder overturning sleeve, and meanwhile, the storage cylinder overturning sleeve has a rotary degree of freedom relative to the pressure regulating piston; the piston rod of the pressure regulating piston extends to the outer side of the fixed limiting sleeve, the pressure regulating piston driving motor is located on the outer side of the fixed limiting sleeve, and a motor shaft of the pressure regulating piston driving motor is in transmission connection with the piston rod of the pressure regulating piston through a crank-link mechanism.
3. The powdered 3D medication printer of claim 2, wherein: the mixing and conveying module comprises a mixing and conveying module bracket, a mixing hopper, a mixture discharging channel, a mixture discharging check valve, a check valve driving motor and a mixture screw conveyer; the mixing hopper is vertically and fixedly arranged under the discharge port of the fixed limiting sleeve, the discharge end of the mixing hopper is communicated with the feed port of the mixture discharge channel, the discharge port of the mixture discharge channel is communicated with the feed port of the mixture screw conveyor, the mixture screw conveyor is vertically arranged on the mixing conveying module support, and the discharge port of the mixture screw conveyor faces downwards; the mixture discharging check valve is arranged at the discharge port of the mixing hopper, the valve spool of the mixture discharging check valve extends to the outer side of the mixing hopper, the check valve driving motor is horizontally and fixedly arranged on the mixing conveying module support, and the motor shaft of the check valve driving motor is fixedly connected with the valve spool of the mixture discharging check valve through a coupling.
4. The powdered 3D medication printer of claim 3, wherein: the molding printing module comprises a platform hot bed, a screw extrusion type printing head, a horizontal position adjusting assembly and a vertical position adjusting assembly; the horizontal position adjusting assembly comprises an X-direction guide optical axis, an X-direction sliding block, a Y-direction guide optical axis, a Y-direction sliding block, a first XY bidirectional adjusting driving motor, a first XY bidirectional synchronous belt transmission mechanism, a second XY bidirectional adjusting driving motor, a second XY bidirectional synchronous belt transmission mechanism, a Z-direction lead screw, a Z-direction screw nut, a Z-direction guide optical axis, a Z-direction sliding sleeve, a Z-direction supporting frame, a Z-direction adjusting driving motor and a Z-direction synchronous belt transmission mechanism; the X-direction guide optical axes adopt a parallel double-shaft structure, the X-direction guide optical axes are horizontally and fixedly arranged on the rack, X-direction sliders are arranged on the two X-direction guide optical axes and can move linearly along the X-direction guide optical axes; the Y-direction guide optical axis is horizontally and fixedly arranged on the X-direction sliding block, the Y-direction guide optical axis adopts a parallel double-shaft structure, the Y-direction sliding block is arranged on the Y-direction guide optical axis, and the Y-direction sliding block can move linearly along the Y-direction guide optical axis; the first XY bidirectional adjusting driving motor is vertically and fixedly arranged on the rack, and is in transmission connection with the X-direction sliding block and the Y-direction sliding block through a first XY bidirectional synchronous belt transmission mechanism; the second XY bidirectional adjusting driving motor is vertically and fixedly arranged on the rack, and is in transmission connection with the X-direction sliding block and the Y-direction sliding block through a second XY bidirectional synchronous belt transmission mechanism; the first XY bidirectional synchronous belt transmission mechanism and the second XY bidirectional synchronous belt transmission mechanism are distributed in mirror symmetry with each other; the Z-direction lead screw is vertically arranged on the rack and has a rotation degree of freedom; the Z-direction guide optical axis adopts a parallel double-shaft structure, the Z-direction guide optical axis is vertically and fixedly arranged on the rack, and the Z-direction lead screw is positioned between the two Z-direction guide optical axes; the Z-direction screw nut is arranged on the Z-direction screw rod, the Z-direction sliding sleeve is arranged on the Z-direction guide optical axis, and the Z-direction supporting frame is fixedly connected between the Z-direction screw nut and the Z-direction sliding sleeve; the platform hot bed is horizontally and fixedly arranged on the Z-direction supporting frame; the Z-direction adjusting driving motor is vertically and fixedly arranged at the bottom of the rack, and is in transmission connection with the Z-direction lead screw through a Z-direction synchronous belt transmission mechanism; the screw extrusion type printing head is vertically and fixedly arranged on the Y-direction sliding block, and a feeding port of the screw extrusion type printing head is communicated with a discharging port of the mixture screw conveyor through a hose; and a heater is arranged on a discharge pipe of the screw extrusion type printing head, and a temperature sensor is arranged in the heater.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010883425.7A CN111920687A (en) | 2020-08-28 | 2020-08-28 | Powder formula 3D medicine printer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010883425.7A CN111920687A (en) | 2020-08-28 | 2020-08-28 | Powder formula 3D medicine printer |
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| CN111920687A true CN111920687A (en) | 2020-11-13 |
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| EP3501793A1 (en) * | 2017-12-21 | 2019-06-26 | ETH Zurich | Pre-mixing and feeding assembly and printhead for 3d printing setup |
| CN212261889U (en) * | 2020-08-28 | 2021-01-01 | 东北大学 | Powder formula 3D medicine printer |
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- 2020-08-28 CN CN202010883425.7A patent/CN111920687A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018210183A1 (en) * | 2017-05-16 | 2018-11-22 | 南京三迭纪医药科技有限公司 | 3d printing device and method |
| EP3501793A1 (en) * | 2017-12-21 | 2019-06-26 | ETH Zurich | Pre-mixing and feeding assembly and printhead for 3d printing setup |
| CN108638289A (en) * | 2018-04-26 | 2018-10-12 | 东北大学 | A kind of large complicated geology physical model 3D formation systems |
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