CN111905206A

CN111905206A - Method and device for determining breathing control curve, electronic equipment and storage medium

Info

Publication number: CN111905206A
Application number: CN202010571999.0A
Authority: CN
Inventors: 李娴; 黄晓燕
Original assignee: First Affiliated Hospital of Guangzhou Medical University
Current assignee: First Affiliated Hospital of Guangzhou Medical University
Priority date: 2020-06-22
Filing date: 2020-06-22
Publication date: 2020-11-10
Anticipated expiration: 2040-06-22
Also published as: CN111905206B

Abstract

The present disclosure relates to a method and apparatus for determining a breathing control curve, an electronic device and a storage medium. The method comprises the following steps: setting a gas supply curve and a gas exhaust curve and measuring an inspiration curve and an expiration curve of a patient; correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve; correcting the air extraction curve according to the expiration curve to obtain a corrected air extraction curve; and determining a respiration control curve based on the correction air supply curve and the correction air exhaust curve. The embodiment of the disclosure can realize the control of air supply and air exhaust according to the breathing condition of a patient.

Description

Method and device for determining breathing control curve, electronic equipment and storage medium

Technical Field

The present disclosure relates to the field of control technologies, and in particular, to a method and an apparatus for determining a respiration control curve, an electronic device, and a storage medium.

Background

The process and principle of respiratory movement in a calm state of a person are as follows: during inspiration, the external intercostal muscles contract, the ribs are lifted, and the sternum moves upwards and outwards, so that the anteroposterior diameter and the left and right diameters of the thorax are increased; meanwhile, the diaphragm muscle contracts, and the top of the diaphragm descends, so that the upper and lower diameters of the thorax are increased. At the moment, the thorax is enlarged, the volume of the lung is increased along with the expansion of the lung, the air pressure in the lung is reduced, and the outside air enters the lung through the respiratory tract to finish the inspiration action; during expiration, the external intercostal muscles relax, the ribs descend under the action of gravity, the sternum moves downwards and inwards, and the anterior-posterior diameter and the left-right diameter of the thorax are reduced: simultaneously, the diaphragm muscle relaxes, and the top of the compartment rises, so that the upper and lower diameters of the thorax are reduced. At this time, the thorax is contracted, the lung is retracted, the volume of the lung is reduced, the air pressure in the lung is increased, and partial air in the alveoli is forced to be exhausted to the outside of the body through the respiratory tract, so that the exhalation action is completed. Thus, the thorax expands and contracts laterally as a result of the contraction and relaxation of the intercostal and diaphragmatic muscles, but at the end of the moment, whether inspiration or expiration, the air pressure in the lungs is equal to the ambient air pressure. It is often seen that some patients with shallow breathing have hypoventilation and hypoxia. When rescuing patients with sudden cessation of breathing, the thorax of the patient is expanded and contracted by artificial respiration to maintain lung ventilation. But care should be taken not to apply too hard to damage the ribs, but to apply a sufficient amplitude to ventilate the alveoli.

The respirator is a device which can replace, control or change the normal physiological respiration of a human, increase the ventilation capacity of the lung, improve the respiratory function, reduce the consumption of the respiratory function and save the reserve capacity of the heart. When the infant is complicated with acute respiratory failure, the infant needs to consider tracheal intubation and a breathing machine due to ineffective active conservative treatment, weakened respiration, excessive and thick phlegm, difficult sputum excretion, airway obstruction or pulmonary atelectasis.

At present, a ventilator respectively performs air supply and air exhaust on lungs according to set air supply curves and air exhaust curves, but the set air supply curves and air exhaust curves do not consider the actual conditions of patients, such as: the air supply curve and the air exhaust curve of the actual demand of the patient. Therefore, the air supply process and the air exhaust process of the patient are unreasonable, such as the problems that the deviation between the air supply curve and the air exhaust curve and the air supply curve and the air exhaust curve actually required by the patient is large, and the air supply amount and the air exhaust amount are too large or too small.

Disclosure of Invention

The present disclosure provides a method and an apparatus for determining a breathing control curve, an electronic device, and a storage medium, which can adjust the air supply and air exhaust control of a ventilator according to the breathing state of a patient, and have better applicability to solve the problem that the air supply process and the air exhaust process of the patient are unreasonable.

According to an aspect of the present disclosure, there is provided a method of determining a breathing control curve, comprising:

setting a gas supply curve and a gas exhaust curve and measuring an inspiration curve and an expiration curve of a patient;

correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve; correcting the air extraction curve according to the expiration curve to obtain a corrected air extraction curve;

and determining a respiration control curve based on the correction air supply curve and the correction air exhaust curve.

Preferably, the method of setting an inspiratory curve and measuring an inspiratory curve of a patient comprises: respectively setting a set air supply speed curve and a set air supply flow curve in the set air supply curve; measuring the inspiratory speed and inspiratory capacity of the patient; respectively determining an inspiration speed curve and an inspiration flow curve in the inspiration curve according to the inspiration speed and the inspiration amount;

and/or the presence of a gas in the interior of the container,

the method for setting the air exhaust curve and measuring the exhalation curve of the patient comprises the following steps: respectively setting a set air extraction speed curve and a set air extraction flow curve in the set air extraction curve; and measuring the expiratory speed and the expiratory volume of the patient; and respectively determining an expiratory speed curve and an expiratory flow curve in the expiratory curve according to the expiratory speed and the expiratory volume.

Preferably, the method for correcting the gas supply curve according to the inhalation curve to obtain a corrected gas supply curve comprises the following steps:

determining a gas feeding speed correction coefficient according to the gas suction speed curve and the set gas feeding speed curve, and multiplying the gas feeding speed correction coefficient by the set gas feeding speed curve to determine a corrected gas feeding speed curve;

determining a supply air flow correction coefficient according to the suction air flow curve and the set supply air flow curve, and multiplying the supply air flow correction coefficient by the set supply air flow curve to determine a corrected supply air flow curve;

and/or the presence of a gas in the interior of the container,

the method for correcting the air exhaust curve according to the expiration curve to obtain the corrected air exhaust curve comprises the following steps:

determining a pumping speed correction coefficient according to the expiration speed curve and the set pumping speed curve, and multiplying the pumping speed correction coefficient by the set pumping speed curve to determine a corrected pumping speed curve;

and determining an air extraction flow correction coefficient according to the expiratory flow curve and the set air extraction flow curve, and multiplying the air extraction flow correction coefficient by the set air extraction flow curve to determine a corrected air extraction flow curve.

Preferably, the method of determining a feed rate correction factor from the inspiratory velocity profile and the set feed rate profile comprises:

calculating a first difference value of the inspiration speed of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiration speed curve and each moment of the set inspiration speed curve, and calculating an absolute value of an average value of the first difference values at each moment;

if the absolute value of the first difference average value is smaller than a first set speed difference value, the air supply speed correction coefficient is configured to be 1;

if the absolute value of the average value of the first difference values is larger than a first set speed difference value, calculating a first ratio of the inspiratory speed of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiratory speed curve to each moment of the set inspiratory speed curve, and averaging the first ratio at each moment to obtain an inspiratory speed correction coefficient;

and/or the presence of a gas in the interior of the container,

the method for determining the air supply flow correction coefficient according to the air suction flow curve and the set air supply flow curve comprises the following steps:

calculating a second difference value between the inspiratory flow of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiratory flow curve and each moment of the set inspiratory flow curve, and calculating an absolute value of an average value of the second difference values at each moment;

if the absolute value of the second difference average value is smaller than a first set flow difference value, the air supply flow correction coefficient is configured to be 1;

if the absolute value of the second difference average value is larger than a first set flow value, calculating a second ratio of the inspiratory flow of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiratory flow curve to each moment of the set inspiratory flow curve, and averaging the second ratio at each moment to obtain an inspiratory flow correction coefficient;

and/or the presence of a gas in the interior of the container,

the method for determining the air pumping speed correction coefficient according to the exhalation speed curve and the set air pumping speed curve comprises the following steps:

calculating a third difference value between the expiration speed of the patient from the beginning expiration to the end expiration at each moment in the expiration speed curve and each moment of the set air pumping speed curve, and calculating an absolute value of an average value of the third difference values at each moment;

if the absolute value of the third difference average value is smaller than a second set speed difference value, the air extraction speed correction coefficient is configured to be 1;

if the absolute value of the average value of the third difference values is larger than a second set speed difference value, calculating a third ratio of the expiratory speed of the patient from the beginning of expiration to the end of expiration at each moment in the expiratory speed curve to each moment of the set pumping speed curve, and averaging the third ratio at each moment to obtain a pumping speed correction coefficient;

and/or the presence of a gas in the interior of the container,

the method for determining the air exhaust flow correction coefficient according to the expiratory flow curve and the set air exhaust flow curve comprises the following steps:

calculating a fourth difference value of the expiratory flow of the patient from the beginning of expiration to the end of expiration at each moment of the expiratory flow curve and each moment of the fixed pumping flow curve, and calculating an absolute value of an average value of the fourth difference values at each moment;

if the absolute value of the fourth difference average value is smaller than a second set flow difference value, the extraction flow correction coefficient is configured to be 1;

if the absolute value of the average value of the fourth difference values is larger than a second set flow value, the expiratory flow curve is calculated, a fourth ratio of the expiratory flow of the patient from beginning expiration to end expiration at each moment to each moment of the set pumping flow curve is calculated, the fourth ratio at each moment is averaged, and the pumping flow correction coefficient is obtained.

Preferably, the method for correcting the gas supply curve according to the inhalation curve to obtain a corrected gas supply curve, and/or the method for correcting the gas extraction curve according to the exhalation curve to obtain a corrected gas extraction curve further includes:

determining a lung injury coefficient according to the chest image data;

determining a first correction coefficient based on the lung injury coefficient and the air feeding speed correction coefficient, and correcting the set air feeding speed curve by using the first correction coefficient to obtain a corrected air feeding speed curve of the corrected air feeding curve;

determining a second correction coefficient based on the lung injury coefficient and the air supply flow correction coefficient, and correcting the set air supply flow curve by using the second correction coefficient to obtain a corrected air supply flow curve of the corrected air supply curve;

determining a third correction coefficient based on the lung injury coefficient and the air pumping speed correction coefficient, and correcting the set air pumping speed curve by using the third correction coefficient to obtain a corrected air pumping speed curve of the corrected air pumping speed curve;

and determining a fourth correction coefficient based on the lung injury coefficient and the air exhaust flow correction coefficient, and correcting the set air exhaust flow curve by using the fourth correction coefficient to obtain a corrected air exhaust flow curve of the corrected air exhaust curve.

Preferably, the method for determining the lung injury coefficient according to the chest image comprises the following steps:

determining whether a lung injury exists according to the chest image data;

if no lung injury exists, configuring a lung injury coefficient as an initial value, if the lung injury exists, correcting the initial value to obtain a corrected lung injury coefficient, and configuring the lung injury coefficient as the corrected lung injury coefficient;

wherein the initial value of the lung injury coefficient is 1;

and/or the presence of a gas in the interior of the container,

the method for determining a first correction factor based on the lung injury factor and the air delivery rate correction factor comprises the following steps: calculating the average value of the lung injury coefficient and the air feeding speed correction coefficient to obtain the first correction coefficient;

the method for determining a second correction coefficient based on the lung injury coefficient and the air supply flow correction coefficient comprises the following steps: calculating the average value of the lung injury coefficient and the air supply flow correction coefficient to obtain the second correction coefficient;

the method for determining the third correction coefficient based on the lung injury coefficient and the air pumping speed correction coefficient comprises the following steps:

calculating the average value of the lung injury coefficient and the air pumping speed correction coefficient to obtain a third correction coefficient;

the method for determining the fourth correction coefficient based on the lung injury coefficient and the air pumping flow correction coefficient comprises the following steps:

and calculating the average value of the lung injury coefficient and the air exhaust flow correction coefficient to obtain the fourth correction coefficient.

Preferably, the method for correcting the initial value to obtain a corrected lung injury coefficient if a lung injury exists includes:

determining a volume of the lung lesion and a volume of both lungs;

correcting the initial value according to the volume of the lung injury and the volume configuration of the two lungs to obtain a corrected lung injury coefficient;

wherein the corrected lung injury coefficient is less than 1.

According to a second aspect of the present disclosure, there is provided an apparatus for determining a breathing control curve, comprising:

the setting unit is used for setting a gas supply curve and a gas extraction curve;

the measuring unit is used for measuring an inspiration curve and an expiration curve of a patient;

the correction unit is used for correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve; correcting the air extraction curve according to the expiration curve to obtain a corrected air extraction curve;

and the determining unit is used for determining a breathing control curve based on the correction air supply curve and the correction air exhaust curve.

According to a third aspect of the present disclosure, there is provided an electronic device comprising: a processor;

a memory for storing processor-executable instructions; wherein the processor is configured to invoke the memory-stored instructions to perform the method of any of the first aspects.

According to a fourth aspect of the present disclosure, a computer-readable storage medium having computer program instructions stored thereon, wherein the computer program instructions, when executed by a processor, implement the method of any of the first aspects.

In the embodiment of the disclosure, the set air supply curve can be corrected by utilizing the inspiration area of the patient, the air exhaust curve can be corrected according to the expiration curve of the patient, and the breathing control curve of the breathing machine can be determined based on the corrected air supply curve and the corrected inspiration curve obtained through correction. The air supply and air exhaust control of the breathing machine can be adjusted according to the breathing state of the patient, and the breathing machine has better applicability.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the disclosure.

Other features and aspects of the present disclosure will become apparent from the following detailed description of exemplary embodiments, which proceeds with reference to the accompanying drawings.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present disclosure and, together with the description, serve to explain the principles of the disclosure.

FIG. 1 shows a flow chart of a method of determining a breathing control curve according to an embodiment of the present disclosure;

FIG. 2 illustrates a block diagram of an electronic device 800 in accordance with an embodiment of the disclosure;

fig. 3 illustrates a block diagram of an electronic device 1900 implemented in accordance with the present disclosure.

Detailed Description

Various exemplary embodiments, features and aspects of the present disclosure will be described in detail below with reference to the accompanying drawings. In the drawings, like reference numbers can indicate functionally identical or similar elements. While the various aspects of the embodiments are presented in drawings, the drawings are not necessarily drawn to scale unless specifically indicated.

The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.

The term "and/or" herein is merely an association describing an associated object, meaning that three relationships may exist, e.g., a and/or B, may mean: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the term "at least one" herein means any one of a plurality or any combination of at least two of a plurality, for example, including at least one of A, B, C, and may mean including any one or more elements selected from the group consisting of A, B and C.

Furthermore, in the following detailed description, numerous specific details are set forth in order to provide a better understanding of the present disclosure. It will be understood by those skilled in the art that the present disclosure may be practiced without some of these specific details. In some instances, methods, means, elements and circuits that are well known to those skilled in the art have not been described in detail so as not to obscure the present disclosure.

It is understood that the above-mentioned method embodiments of the present disclosure can be combined with each other to form a combined embodiment without departing from the logic of the principle, which is limited by the space, and the detailed description of the present disclosure is omitted.

In addition, the present disclosure also provides a device, an electronic device, a computer-readable storage medium, and a program for determining a respiration control curve, which can be used to implement any one of the methods for determining a respiration control curve provided by the present disclosure, and the corresponding technical solutions and descriptions and corresponding descriptions in the methods section are omitted for brevity.

The subject of execution of the method of determining a breathing control curve may be a ventilator or other apparatus for determining a breathing control curve, for example, the method may be performed by a terminal device or a server or other processing device, where the terminal device may be a User Equipment (UE), a mobile device, a User terminal, a cellular phone, a cordless phone, a Personal Digital Assistant (PDA), a handheld device, a computing device, a vehicle mounted device, a wearable device, or the like. In some possible implementations, the method of determining a breathing control curve may be implemented by a processor invoking computer readable instructions stored in a memory.

Fig. 1 shows a flowchart of a method of determining a breathing control curve according to an embodiment of the present disclosure, which, as shown in fig. 1, may include:

s10: setting a gas supply curve and a gas exhaust curve and measuring an inspiration curve and an expiration curve of a patient;

s20: correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve; correcting the air extraction curve according to the expiration curve to obtain a corrected air extraction curve;

s30: and determining a respiration control curve based on the correction air supply curve and the correction air exhaust curve.

Based on the configuration, the embodiment of the disclosure can correct the set air supply curve by using the inspiration area of the patient, correct the air exhaust curve according to the expiration curve of the patient, and determine the breathing control curve of the breathing machine based on the corrected air supply curve and the corrected inspiration curve. The air supply and air exhaust control of the breathing machine can be adjusted according to the breathing state of the patient, and the breathing machine has better applicability.

The steps of the disclosed embodiments are described in detail below.

wherein the method of setting an inspiratory curve and measuring an inspiratory curve of a patient may comprise: respectively setting a set air supply speed curve and a set air supply flow curve in the set air supply curve; measuring the inspiratory speed and inspiratory capacity of the patient; and respectively determining an inspiration speed curve and an inspiration flow curve in the inspiration curve according to the inspiration speed and the inspiration amount. And/or, the method of setting a pumping profile and measuring an exhalation profile of a patient, comprising: respectively setting a set air extraction speed curve and a set air extraction flow curve in the set air extraction curve; and measuring the expiratory speed and the expiratory volume of the patient; and respectively determining an expiratory speed curve and an expiratory flow curve in the expiratory curve according to the expiratory speed and the expiratory volume.

This disclosed embodiment can set for the curve of giving the gas and the curve of bleeding of breathing machine, give the gas curve and include: setting a gas supply speed curve and a gas supply flow curve, wherein the gas extraction curve comprises: setting an air extraction speed curve and an air extraction flow curve; when the breathing machine starts to supply air, supplying air according to the set air supply speed curve and the set air supply flow curve; and when the respirator starts to perform air suction, air suction is performed according to the set air suction speed curve and the set air suction flow curve. Namely, obtaining the air supply curve of the breathing machine according to the set air supply speed curve and the set air supply flow curve; and obtaining the air supply curve of the breathing machine according to the set air supply speed curve and the set air supply flow curve.

In the present invention and its specific embodiments, the set air supply speed curve and the set air supply flow curve in the air supply curve of the ventilator, and the set air extraction speed curve and the set air extraction flow curve in the air extraction curve of the ventilator are all the air supply speed, the air supply flow, the air extraction speed and the air extraction flow collected during the breathing process of a normal person who does not have dyspnea.

In the present invention and its embodiments, the method of determining the set air feed speed profile and the set air feed flow profile comprises: acquiring N groups of data of inspiration speed and inspiration flow of N normal persons without dyspnea from the beginning to the end of inspiration; and respectively averaging the data of the N groups of the air suction speeds and the air suction flow to obtain the set air supply speed curve and the set air supply flow curve. The abscissa of the set air supply speed curve is time in units: and the ordinate of the set air feeding speed curve is the air feeding speed. The abscissa of the set air supply flow curve is time in units: and second, the ordinate of the set air supply flow curve is the air supply flow. In order to ensure that the set air feed speed curve and the set air feed flow curve have statistical significance, N is more than or equal to 50.

More specifically, acquiring inspiration time from the beginning to the end of inspiration of N normal persons without dyspnea, dividing the N groups of inspiration speed and inspiration flow data into N inspiration intervals according to the inspiration time, respectively averaging the N groups of inspiration speed and inspiration flow data at each time point in the N inspiration intervals, then respectively performing linear fitting on the obtained average values of the N groups of inspiration speeds, and performing linear fitting on the obtained average values of the N groups of inspiration flow to obtain a sub-set air-feeding speed curve and a sub-set air-feeding flow curve in each inspiration interval, and further obtaining N sub-set air-feeding speed curves and N sub-set air-feeding flow curves, wherein the N sub-set air-feeding speed curves and the N sub-set air-feeding flow curves form the set air-feeding speed curve and the set air-feeding flow curve, n is more than or equal to 50. In addition, the linear fitting method may include a least squares method, or may also include other methods, which are not specifically limited by the present disclosure.

In the present invention and its embodiments, the method for determining the set pumping speed curve and the set pumping flow curve comprises: acquiring M groups of expiratory speed and expiratory flow data of M normal persons without dyspnea from beginning expiration to end expiration; and respectively averaging the M groups of data of the expiratory speed and the expiratory flow to obtain the set air exhaust speed curve and the set air exhaust flow curve. The abscissa of the set air exhaust flow curve is time in unit: second, the ordinate of the air exhaust flow curve is the expiratory flow; the abscissa of the set pumping speed curve is time in unit: and the ordinate of the air pumping speed curve is speed.

More specifically, acquiring the expiration time from the beginning to the end of expiration of M normal persons without dyspnea, dividing the M groups of data of expiration speed and expiration flow into M air extraction intervals according to the expiration time, respectively averaging the M groups of data of expiration speed and expiration flow at each time point in the M air extraction intervals, then respectively carrying out linear fitting on the obtained average values of the M groups of expiratory speeds and carrying out linear fitting on the obtained average values of the M groups of airflow to obtain a sub-set air-extracting speed curve and a sub-set air-extracting flow curve in each expiratory interval, and further obtaining M sub-set air-extracting speed curves and M sub-set air-extracting flow curves, the m sub-set pumping speed curves and the m sub-set pumping flow curves respectively form the set pumping speed curve and the set pumping flow curve. In order to ensure that the set expiratory speed and the set expiratory flow have a statistical significance, M.gtoreq.50, m.gtoreq.50.

In embodiments of the present invention, airway velocity and airway flow within the respiratory tract of a patient may also be detected in real-time. When the breathing machine starts to supply air, calculating a difference value between the air supply speed and the air passage speed in a set air supply speed curve, obtaining an air supply adjusting speed according to the difference value so as to adjust the air supply speed of the breathing machine, and supplying air by the breathing machine according to the air supply adjusting speed; when the respirator starts to exhaust, the difference value of the air exhaust speed and the air passage speed in the set air exhaust speed curve is calculated, the air exhaust adjusting speed is obtained according to the difference value so as to adjust the air exhaust speed of the respirator, and the respirator performs air exhaust according to the air exhaust adjusting speed. The speed of the air passage is ensured to be respectively consistent with the air supply speed in the set air supply speed curve and the air exhaust speed in the set air exhaust speed curve, and the air supply speed and the air exhaust speed of the breathing machine are controlled more accurately. The air supply speed can be adjusted under the condition that the difference value between the air supply speed and the air passage speed in the set air supply speed curve is calculated to exceed the first threshold, and the air suction speed is adjusted when the difference value between the air suction speed and the air passage speed in the set air suction speed curve is calculated to exceed the second threshold, so that the frequent operation of the breathing machine is reduced. The first threshold and the second threshold may be set according to requirements, and the disclosure is not limited in detail herein.

Meanwhile, in the specific embodiment of the invention, when the breathing machine starts to give gas, the difference value of the gas-supply flow and the air passage flow in the set gas-supply flow curve is calculated to obtain the gas-supply regulation flow, the gas-supply flow of the breathing machine is regulated according to the difference value, and the breathing machine supplies gas according to the gas-supply regulation flow; when the respirator starts to exhaust, the difference value of the exhaust flow and the airway flow in the set exhaust speed curve is calculated, the exhaust flow of the respirator is adjusted according to the difference value, the exhaust adjusting flow is obtained, and the respirator performs exhaust according to the exhaust adjusting flow. So as to ensure that the flow of the air passage is respectively consistent with the air supply flow in the set air supply flow curve and the air exhaust flow in the set air exhaust flow curve. Similarly, the embodiment of the disclosure may also adjust the supply air flow when the difference between the supply air flow and the air passage flow in the set supply air flow curve exceeds a third threshold, and adjust the extraction air flow when the difference between the extraction air flow and the air passage flow in the set extraction air speed curve exceeds a fourth threshold. The third threshold and the fourth threshold can be set according to requirements.

In one embodiment of the present invention, the airway is a first airway C, and the air is supplied or pumped through the first airway C and a second airway D into the left lung and the right lung, respectively. Further, the airway may be a second airway, controlling the flow rate and volume of second airway E into the left lung and second airway D into the right lung, respectively.

Obviously, the ventilator may comprise: first breathing machine and second breathing machine or two work units of a breathing are constituteed, two work units all can accomplish the inflation and the air exhaust of left lung or right lung, for more convenient the explanation, all follow: the first and second ventilators will be explained.

In the present invention and its specific embodiments, the setting of the air feed speed profile includes: a first set air feed speed curve and a second set air feed speed curve; the set air feed flow curve includes: a first set air supply flow curve and a second set air supply flow curve; and the first respirator supplies air to the left lung according to the first set air supply speed curve and the first set air supply flow curve, or the second respirator supplies air to the right lung according to the second set air supply speed curve and the second set air supply flow curve.

Meanwhile, in the present invention and its specific embodiments, the setting of the pumping speed profile includes: a first set pumping speed curve and a second set pumping speed curve; the set air exhaust flow curve comprises: a first set pumping flow curve and a second set pumping flow curve; the first respirator performs air extraction on the left lung according to the first set air extraction speed curve and the first set air extraction flow curve, or the second respirator performs air extraction on the right lung according to the second set air extraction speed curve and the second set air extraction flow curve.

In an embodiment of the present invention, a method for determining the first set air supply speed curve, the first set air supply flow rate curve, the second set air supply speed curve and the second set air supply flow rate curve includes: acquiring N groups of left lung data and right lung data of inspiration speed and inspiration flow from the beginning to the end of inspiration of N normal persons without dyspnea; and respectively averaging the N groups of left lung data and right lung data to obtain the first set air supply speed curve and the first set air supply flow curve of the left lung, and the second set air supply speed curve and the second set air supply flow curve of the right lung. In order to ensure that the set air feed speed curve and the set air feed flow curve have statistical significance, N is more than or equal to 50.

More specifically, average inspiration time from the beginning to the end of inspiration of N normal persons without dyspnea is obtained, the N groups of left lung data and right lung data of inspiration speed and inspiration flow are divided into N left lung inspiration intervals and N right lung inspiration intervals according to the average inspiration time, and the time of each inspiration interval is average inspiration time/N; and respectively averaging the data of the inspiration speed and the inspiration flow in the inspiration interval of the n left lungs and the inspiration interval of the right lung to obtain a first sub-set inspiration speed curve and a first sub-set inspiration flow curve of the n left lungs and a second sub-set inspiration speed curve and a second sub-set inspiration flow curve of the n right lungs. The first sub-set air supply speed curves of the n left lungs and the first sub-set air supply flow curves of the n left lungs respectively form a first set air supply speed curve and a first set air supply flow curve; the second sub-set air supply speed curves of the n right lungs and the second sub-set air supply flow curves of the n right lungs respectively form a second set air supply speed curve and a second set air supply flow curve, and n is larger than or equal to 50.

In an embodiment of the present invention, a method for determining a first set pumping speed profile, a second set pumping speed profile, a first set pumping flow profile, and a second set pumping flow profile comprises: acquiring M groups of left lung data and right lung data of expiratory speed and expiratory flow of M normal persons without dyspnea from beginning expiration to end expiration; and respectively averaging the left lung data and the right lung data to obtain a first set air exhaust speed curve and a first set air exhaust flow curve of the left lung, and a second set air exhaust speed curve and a second set air exhaust flow curve of the right lung.

More specifically, acquiring average expiration time from beginning expiration to end expiration of M normal persons without dyspnea, dividing the M groups of data of expiration speed and expiration flow into M air extraction intervals according to the average expiration time, and respectively averaging the M groups of data of expiration speed and expiration flow in the M air extraction intervals; and obtaining a first sub-set air-extracting speed curve of the m left lungs, a first sub-set air-extracting flow curve of the m left lungs, a second sub-set air-extracting speed curve of the m right lungs and a second sub-set air-extracting flow curve of the m right lungs, wherein the time of each expiration interval is the average expiration time/m. The m sub-set pumping speed curves and the m sub-set pumping flow curves respectively form the set pumping speed curve and the set pumping flow curve.

The first sub-set air-extracting speed curves of the m left lungs and the first sub-set air-extracting flow curves of the m left lungs respectively form a first set air-extracting speed curve and a first set air-extracting flow curve; the second sub-set pumping speed curves of the m right lungs and the second sub-set pumping flow curves of the m right lungs respectively form the second set pumping speed curve and the second set pumping flow curve. In order to ensure that the set expiratory speed and the set expiratory flow have a statistical significance, M.gtoreq.50, m.gtoreq.50.

In a specific embodiment of the present invention, determining the inspiratory curve of the patient may include determining the inspiratory rate and inspiratory volume of the patient during respiration, and determining the expiratory curve of the patient may include determining the expiratory rate and expiratory volume of the patient during respiration, wherein the inspiratory rate, inspiratory volume, expiratory rate and expiratory volume may be determined by a spirometric method. The method for determining the inspiration speed, the inspiration amount, the expiration speed and the expiration amount of the patient comprises the following steps: the inspiration speed and the inspiration amount of the patient from the beginning of inspiration to the end of inspiration are measured, and the expiration speed and the expiration amount of the patient from the beginning of expiration to the end of expiration are measured. In a specific embodiment of the present invention, the method for determining the inspiratory rate, inspiratory volume, expiratory rate and expiratory volume of the patient can be determined by a spirometric method. The method for determining the inspiration speed, the inspiration amount, the expiration speed and the expiration amount of the patient comprises the following steps: the inspiration speed and the inspiration amount of the patient from the beginning of inspiration to the end of inspiration are measured, and the expiration speed and the expiration amount of the patient from the beginning of expiration to the end of expiration are measured.

Based on the above configuration, the inhalation curve and the exhalation curve of the patient, and the set administration curve and inhalation curve can be obtained. Step S20 may then be performed.

S20: correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve; and correcting the air exhaust curve according to the expiration curve to obtain a corrected air exhaust curve.

In an embodiment of the present disclosure, the method for correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve includes: determining a gas feeding speed correction coefficient according to the gas suction speed curve and the set gas feeding speed curve, and multiplying the gas feeding speed correction coefficient by the set gas feeding speed curve to determine a corrected gas feeding speed curve; determining a supply air flow correction coefficient according to the suction air flow curve and the set supply air flow curve, and multiplying the supply air flow correction coefficient by the set supply air flow curve to determine a corrected supply air flow curve; and/or the method for correcting the air exhaust curve according to the expiration curve to obtain the corrected air exhaust curve comprises the following steps: determining a pumping speed correction coefficient according to the expiration speed curve and the set pumping speed curve, and multiplying the pumping speed correction coefficient by the set pumping speed curve to determine a corrected pumping speed curve; and determining an air extraction flow correction coefficient according to the expiratory flow curve and the set air extraction flow curve, and multiplying the air extraction flow correction coefficient by the set air extraction flow curve to determine a corrected air extraction flow curve.

In an embodiment of the present invention, the ventilation curve of the ventilator further comprises: the first correction coefficient and the second correction coefficient are respectively a gas velocity correction coefficient and a flow correction coefficient of a gas supply curve of the breathing machine; the air exhaust curve comprises: the third correction coefficient and the fourth correction coefficient are respectively a gas velocity correction coefficient and a flow correction coefficient of an air exhaust curve of the breathing machine; obtaining a corrected air feeding speed curve according to the set air feeding speed curve and the first correction coefficient; obtaining a corrected air supply flow curve according to the set air supply flow curve and the second correction coefficient; obtaining a corrected pumping speed curve according to the set pumping speed curve and the third correction coefficient; obtaining a corrected pumping flow curve according to the set pumping flow curve and the fourth correction coefficient; the breathing machine supplies air according to the corrected air supply speed curve and the corrected air supply flow curve; and the breathing machine performs air supply according to the corrected air supply speed curve and the corrected air supply flow curve.

In an embodiment of the present invention, a method of determining the first correction coefficient, the second correction coefficient, the third correction coefficient, and the fourth correction coefficient includes: determining the inspiration speed, inspiration volume, expiration speed and expiration volume of a patient; determining lung injury from the chest image data; and respectively determining the first correction coefficient, the second correction coefficient, the third correction coefficient and the fourth correction coefficient according to the lung injury, the inspiration amount and the expiration amount. The first correction coefficient, the second correction coefficient, the third correction coefficient and the fourth correction coefficient are respectively multiplied by the set air supply speed curve, the set air supply flow curve, the set air extraction speed curve and the set air extraction flow curve to obtain the corrected air supply speed curve, the corrected air supply flow curve, the corrected air extraction speed curve and the corrected air extraction flow curve.

In a specific embodiment of the present invention, a method of determining the first correction coefficient includes: respectively determining an air supply speed correction coefficient and/or a lung injury coefficient, and obtaining the first correction coefficient according to the air supply speed correction coefficient and/or the lung injury coefficient; a method of determining the second correction coefficient, comprising: respectively determining an air supply flow correction coefficient and/or a lung injury coefficient, and obtaining a second correction coefficient according to the air supply flow correction coefficient and/or the lung injury coefficient; a method of determining the third correction factor, comprising: respectively determining an air pumping speed correction coefficient and/or a lung injury coefficient, and obtaining a third correction coefficient according to the air pumping speed correction coefficient and/or the lung injury coefficient; a method of determining the fourth correction factor, comprising: and respectively determining an air extraction flow correction coefficient and/or a lung injury coefficient, and obtaining the fourth correction coefficient according to the air extraction flow correction coefficient and/or the lung injury coefficient.

In a specific embodiment of the present invention, the corrected air delivery rate profile may be determined by multiplying the air delivery rate correction factor or the lung injury factor in the first correction factor by the set air delivery rate profile; similarly, a corrected air supply flow rate curve may be determined by multiplying a set air supply flow rate curve by an air supply flow rate correction coefficient and/or a lung injury coefficient in the second correction coefficient; a corrected pumping speed curve can be determined by multiplying a set pumping speed curve by a pumping speed correction coefficient or a lung injury coefficient in the third correction coefficient; the corrected aspiration flow curve may be determined by multiplying the set aspiration flow curve by an aspiration flow correction coefficient or a lung injury coefficient of the fourth correction coefficient.

The following provides a specific method for determining the give/aspirate speed/flow correction curve based on the give/aspirate speed/flow correction factor and the lung injury factor. The method for obtaining the first correction coefficient according to the air supply speed correction coefficient and the lung injury coefficient comprises the following steps: and calculating the average value of the air feeding speed correction coefficient and the lung injury coefficient to obtain the first correction coefficient. The method for obtaining the second correction coefficient according to the air supply flow correction coefficient and the lung injury coefficient comprises the following steps: and calculating the average value of the air supply flow correction coefficient and the lung injury coefficient to obtain the second correction coefficient. The method for obtaining the third correction coefficient according to the pumping speed correction coefficient and the lung injury coefficient comprises the following steps: and calculating the average value of the air pumping speed correction coefficient and the lung injury coefficient to obtain the third correction coefficient. The method for obtaining the fourth correction coefficient according to the air exhaust flow correction coefficient and the lung injury coefficient comprises the following steps. And calculating the average value of the air exhaust flow correction coefficient and the lung injury coefficient to obtain the fourth correction coefficient.

In a specific embodiment of the invention, the lung injury is a thoracic surgical condition, the lung is relatively resistant to penetrating injury (other than high velocity projections), the lung parenchyma has good repair ability, unless the lung portal structure is damaged, generally air leakage and bleeding of lung tissue will stop soon, and the parenchymal injury of the surrounding part needs to be cut off rarely; blunt lung injury, on the other hand, although causing a lesser degree of local injury, can lead to more serious and even life-threatening complications due to the increased total area and secondary reactive changes of multiple injury. Wherein, the degree of lung injury can be represented by a lung injury coefficient.

In an embodiment of the present disclosure, the method for determining a gas supply speed correction coefficient according to the air suction speed curve and the set gas supply speed curve includes: calculating a first difference value of the inspiration speed of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiration speed curve and each moment of the set inspiration speed curve, and calculating an absolute value of an average value of the first difference values at each moment; if the absolute value of the first difference average value is smaller than a first set speed difference value, the air supply speed correction coefficient is configured to be 1; if the absolute value of the average value of the first difference values is larger than a first set speed difference value, calculating a first ratio of the inspiratory speed of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiratory speed curve to each moment of the set inspiratory speed curve, and averaging the first ratio at each moment to obtain an inspiratory speed correction coefficient.

That is, the embodiment of the present disclosure may calculate a first difference between the inspiratory speed of the patient from the beginning of inspiration to the end of inspiration at each time and each time of the set inspiratory speed curve, and calculate an absolute value of an average value of the first difference at each time; if the absolute value of the first difference average value is smaller than a first set speed difference value, the air supply speed correction coefficient is configured to be 1; if the absolute value of the average value of the first difference values is larger than a first set speed difference value, calculating a first ratio of the inspiration speed of the patient from beginning to end of inspiration at each moment to each moment of the set air feeding speed curve, and averaging the first ratio at each moment to obtain an air feeding speed correction coefficient.

In addition, the method for determining the air supply flow correction coefficient according to the air suction flow curve and the set air supply flow curve comprises the following steps: calculating a second difference value between the inspiratory flow of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiratory flow curve and each moment of the set inspiratory flow curve, and calculating an absolute value of an average value of the second difference values at each moment; if the absolute value of the second difference average value is smaller than a first set flow difference value, the air supply flow correction coefficient is configured to be 1; if the absolute value of the second difference average value is larger than a first set flow value, calculating a second ratio of the inspiratory flow of the patient from the beginning of inspiration to the end of inspiration at each moment in the inspiratory flow curve to each moment of the set inspiratory flow curve, and averaging the second ratio at each moment to obtain an inspiratory flow correction coefficient;

that is, the embodiment of the present disclosure may calculate a second difference between the inspiratory flow of the patient from the beginning of inspiration to the end of inspiration at each time and each time of the set inspiratory flow curve, and calculate an absolute value of an average value of the second difference at each time; if the absolute value of the second difference average value is smaller than a first set flow difference value, the air supply flow correction coefficient is configured to be 1; if the absolute value of the second difference average value is larger than the first set flow value, calculating a second ratio of the inspiratory flow of the patient from the beginning of inspiration to the end of inspiration at each moment to each moment of the set inspiratory flow curve, and averaging the second ratio at each moment to obtain the inspiratory flow correction coefficient.

In addition, the method for determining the air pumping speed correction coefficient according to the exhalation speed curve and the set air pumping speed curve comprises the following steps: calculating a third difference value between the expiration speed of the patient from the beginning expiration to the end expiration at each moment in the expiration speed curve and each moment of the set air pumping speed curve, and calculating an absolute value of an average value of the third difference values at each moment; if the absolute value of the third difference average value is smaller than a second set speed difference value, the air extraction speed correction coefficient is configured to be 1; if the absolute value of the average value of the third difference values is larger than a second set speed difference value, calculating a third ratio of the expiratory speed of the patient from the beginning of expiration to the end of expiration at each moment in the expiratory speed curve to each moment of the set pumping speed curve, and averaging the third ratio at each moment to obtain a pumping speed correction coefficient.

In an embodiment of the present invention, a third difference between the expiration speed of the patient from the beginning of expiration to the end of expiration at each time and each time of the set pumping speed curve may be calculated, and an absolute value of an average value of the third difference at each time may be calculated; if the absolute value of the third difference average value is smaller than a second set speed difference value, the air extraction speed correction coefficient is configured to be 1; if the absolute value of the average value of the third difference values is larger than a second set speed difference value, calculating a third ratio of the expiratory speed of the patient from the beginning of expiration to the end of expiration at each moment to each moment of the set pumping speed curve, and averaging the third ratio at each moment to obtain a pumping speed correction coefficient.

In addition, the method for determining the extraction flow correction coefficient according to the expiratory flow curve and the set extraction flow curve comprises the following steps: calculating a fourth difference value of the expiratory flow of the patient from the beginning of expiration to the end of expiration at each moment of the expiratory flow curve and each moment of the fixed pumping flow curve, and calculating an absolute value of an average value of the fourth difference values at each moment; if the absolute value of the fourth difference average value is smaller than a second set flow difference value, the extraction flow correction coefficient is configured to be 1; if the absolute value of the average value of the fourth difference values is larger than a second set flow value, the expiratory flow curve is calculated, a fourth ratio of the expiratory flow of the patient from beginning expiration to end expiration at each moment to each moment of the set pumping flow curve is calculated, the fourth ratio at each moment is averaged, and the pumping flow correction coefficient is obtained.

In an embodiment of the present invention, a fourth difference between the expiratory flow of the patient from the beginning of expiration to the end of expiration at each time and each time of the fixed pumping flow curve may be calculated, and an absolute value of an average value of the fourth difference at each time may be calculated; if the absolute value of the fourth difference average value is smaller than a second set flow difference value, the extraction flow correction coefficient is configured to be 1; if the absolute value of the average value of the fourth difference values is larger than a second set flow value, calculating a fourth ratio of the expiratory flow of the patient from the beginning of expiration to the end of expiration at each moment to the set exhaust flow curve at each moment, and averaging the fourth ratio at each moment to obtain the exhaust flow correction coefficient.

In addition, in this disclosure, the method for obtaining a corrected gas supply curve by correcting the gas supply curve according to the inhalation curve and/or the method for obtaining a corrected gas extraction curve by correcting the gas extraction curve according to the exhalation curve further includes: determining a lung injury coefficient according to the chest image data; determining a first correction coefficient based on the lung injury coefficient and the air feeding speed correction coefficient, and correcting the set air feeding speed curve by using the first correction coefficient to obtain a corrected air feeding speed curve of the corrected air feeding curve; determining a second correction coefficient based on the lung injury coefficient and the air supply flow correction coefficient, and correcting the set air supply flow curve by using the second correction coefficient to obtain a corrected air supply flow curve of the corrected air supply curve; determining a third correction coefficient based on the lung injury coefficient and the air pumping speed correction coefficient, and correcting the set air pumping speed curve by using the third correction coefficient to obtain a corrected air pumping speed curve of the corrected air pumping speed curve; and determining a fourth correction coefficient based on the lung injury coefficient and the air exhaust flow correction coefficient, and correcting the set air exhaust flow curve by using the fourth correction coefficient to obtain a corrected air exhaust flow curve of the corrected air exhaust curve.

And under the condition of lung injury, the air supply curve and the air exhaust curve can be corrected to obtain a corrected proper air supply curve and air exhaust curve, and the respirator is controlled to supply air and exhaust air according to the corrected air supply curve and air exhaust curve.

The method for determining lung injury according to chest image data comprises the following steps: acquiring chest image data; and determining whether lung injury exists according to the chest image data, configuring a lung injury coefficient as an initial value if the lung injury does not exist, correcting the initial value to obtain a corrected lung injury coefficient if the lung injury exists, and configuring the lung injury coefficient as the corrected lung injury coefficient. Wherein the initial value of the lung injury coefficient is 1.

The method for correcting the initial value to obtain the corrected lung injury coefficient if the lung injury exists comprises the following steps: determining a volume of the lung lesion and a volume of both lungs; correcting the initial value according to the volume of the lung injury and the volumes of the two lungs to obtain a corrected lung injury coefficient; wherein the corrected lung injury coefficient is less than 1. Specifically, the method for obtaining the corrected lung injury coefficient according to the injured volume and the volumes of the two lungs comprises the following steps: calculating a ratio of the volume of the lesion to the volume of the lungs, the ratio being configured as the resulting lung lesion coefficient. For example, the ratio of the volume of the lesion to the volume of the lungs is 0.8, and the lung lesion coefficient is configured to be 0.8.

Meanwhile, in the above embodiment, a method of the first ventilator supplying air to the left lung according to the first set air supply speed curve and the first set air supply flow curve, or a method of the first ventilator supplying air to the right lung according to the second set air supply speed curve and the second set air supply flow curve, and a method of the second ventilator extracting air to the left lung according to the first set air extraction speed curve and the first set air extraction flow curve, or a method of the second ventilator extracting air to the right lung according to the second set air extraction speed curve and the second set air extraction flow curve are provided. With the combination of the above embodiments, the present invention can control the ventilator to perform air supply and air exhaust to the left lung and the right lung respectively.

The first correction coefficient includes: a first left lung correction coefficient and a first right lung correction coefficient. The method of the first left lung correction factor, comprising: determining an air feeding speed correction coefficient and/or a left lung injury coefficient of a left lung of a patient, and obtaining the first left lung correction coefficient according to the air feeding speed correction coefficient and/or the left lung injury coefficient of the left lung. The method of the first right lung correction factor, comprising: determining an air feeding speed correction coefficient and/or a right lung injury coefficient of the right lung of the patient, and obtaining the first right lung correction coefficient according to the air feeding speed correction coefficient and/or the right lung injury coefficient of the right lung. The detailed process can refer to the above description of the air supply speed correction coefficient of the whole lung (left lung and right lung) or other relevant contents. And the first left lung correction coefficient is multiplied by the first set air supply speed curve to obtain a first corrected air supply speed curve, and the first right lung correction coefficient is multiplied by the second set air supply speed curve to obtain a second corrected air supply speed curve.

The second correction coefficient includes: a second left lung correction coefficient and a second right lung correction coefficient. The method of the second left lung correction factor, comprising: and determining the air supply flow correction coefficient and/or the left lung injury coefficient of the left lung of the patient, and obtaining the second left lung correction coefficient according to the air supply flow correction coefficient and/or the left lung injury coefficient of the left lung. The method of the second right lung correction factor, comprising: and determining the air supply flow correction coefficient and/or the right lung injury coefficient of the right lung of the patient, and obtaining the second right lung correction coefficient according to the air supply flow correction coefficient and/or the right lung injury coefficient of the right lung. The detailed process can refer to the above description of the air supply speed correction coefficient of the whole lung (left lung and right lung) or other relevant contents. And the second left lung correction coefficient is multiplied by the first set air supply flow curve to obtain a first corrected air supply flow curve, and the first right lung correction coefficient is multiplied by the second set air supply flow curve to obtain a second corrected air supply flow curve.

In summary, the first ventilator delivers the air to the left lung according to the first corrected air delivery speed curve and the first corrected air delivery flow curve, and the second ventilator delivers the air to the right lung according to the second corrected air delivery speed curve and the second corrected air delivery flow curve. The first respirator is used for respectively exhausting air to the left lung according to the first correction air exhausting speed curve and the first correction air exhausting flow curve, and the second respirator is used for respectively exhausting air to the right lung according to the second correction air exhausting speed curve and the second correction air exhausting flow curve.

The third correction coefficient includes: a third left lung correction coefficient and a third right lung correction coefficient. The method of the third left lung correction factor, comprising: and determining the air pumping speed correction coefficient and/or the left lung injury coefficient of the left lung of the patient, and obtaining the third left lung correction coefficient according to the air pumping speed correction coefficient and/or the left lung injury coefficient of the left lung. The method of the third right lung correction factor, comprising: and determining the air pumping speed correction coefficient and/or the right lung injury coefficient of the right lung of the patient, and obtaining the third right lung correction coefficient according to the air pumping speed correction coefficient and/or the right lung injury coefficient of the right lung. The detailed process can refer to the above description of the correction coefficient of the pumping flow of the whole lung (left lung and right lung) or other relevant contents. And multiplying the third left lung correction coefficient by the first set pumping speed curve to obtain a first corrected pumping speed curve, and multiplying the third right lung correction coefficient by the second set pumping speed curve to obtain a second corrected pumping speed curve.

The fourth correction coefficient includes: a fourth left lung correction coefficient and a fourth right lung correction coefficient. The fourth left lung correction coefficient method, comprising: and determining an air extraction flow correction coefficient and/or a left lung injury coefficient of the left lung of the patient, and obtaining a fourth left lung correction coefficient according to the air extraction flow correction coefficient and/or the left lung injury coefficient of the left lung. The fourth right lung correction coefficient method, comprising: and determining the air extraction flow correction coefficient and/or the right lung injury coefficient of the right lung of the patient, and obtaining the fourth right lung correction coefficient according to the air extraction flow correction coefficient and/or the right lung injury coefficient of the right lung. The detailed process can refer to the above description of the correction coefficient of the pumping flow of the whole lung (left lung and right lung) or other relevant contents. And the fourth left lung correction coefficient is multiplied by the first set air exhaust flow curve to obtain a second corrected air exhaust flow curve, and the right lung correction coefficient is multiplied by the second set air exhaust flow curve to obtain a second corrected air exhaust flow curve.

In summary, the first ventilator respectively performs ventilation on the left lung and the right lung according to the first corrected ventilation speed curve and the second corrected ventilation speed curve, and the first ventilator respectively performs ventilation on the left lung and the right lung according to the first corrected ventilation flow curve and the second corrected ventilation flow curve.

The lung injury coefficient described above, comprising: left lung injury coefficient and right lung injury coefficient. The method for correcting the initial value to obtain a corrected lung injury coefficient if lung injury exists, and configuring the injury coefficient as the corrected lung injury coefficient, further includes: determining a volume of lung injury of the left lung and the left lung; determining a volume of lung lesions of the right lung and the right lung; and determining the left lung injury coefficient according to the volumes of the lung injuries of the left lung and the left lung, and determining the left lung injury coefficient according to the volumes of the lung injuries of the left lung and the left lung. For example, the ratio of the volume of the left lung lesion to the volume of the left lung is 0.8, and the left lung lesion coefficient is configured to be 0.8. The ratio of the volume of the right lung injury to the volume of the right lung is 0.7, and the right lung injury factor is configured to be 0.7.

When the corrected ventilation curve and the corrected air extraction curve are obtained, the above-mentioned curves can be used as the breathing control curves for controlling the ventilator to perform air extraction and ventilation. That is, the breathing control curve is determined based on the corrected ventilation curve and the corrected air-extraction curve, and the obtained corrected ventilation curve and the corrected air-extraction curve may be used as the breathing control curve of the ventilator, so that ventilation and inspiration control at each time is realized.

In the method of the present invention, further comprising: setting the maximum air supply time and the maximum air stop time of the breathing machine; recording the air supply duration of the breathing machine, and if the air supply duration is greater than or equal to the maximum air supply time, sending a first switching instruction, wherein the breathing machine converts the positive pressure instruction into the negative pressure instruction according to the first switching instruction; recording the air stopping duration of the breathing machine, and if the air stopping duration is greater than or equal to the maximum air stopping time, sending a second switching instruction, wherein the breathing machine converts the negative pressure instruction into the positive pressure instruction according to the second switching instruction.

In the method of the present invention, further comprising: further comprising: if the gas supply duration is greater than or equal to the maximum gas supply time, or if the gas stopping duration is greater than or equal to the maximum gas stopping time, sending an early warning signal; and the respirator carries out early warning prompt according to the early warning signal.

The method of the disclosed embodiment further comprises: detecting a first dynamic pressure at the top in the lung cavity and a second dynamic pressure at the bottom in the lung cavity in real time; and comparing the first dynamic pressure and the second dynamic pressure with a preset first interval and a preset second interval respectively to obtain a positive pressure instruction or a negative pressure instruction, and controlling the breathing machine to be switched from an air pumping state to an air inflation state according to the positive pressure instruction or controlling the breathing machine to be switched from the air inflation state to the air pumping state according to the negative pressure instruction.

In the embodiment of the invention, the lung cavity is a cavity in which the two lungs and the heart are located, the whole cavity of the human body is divided into the lung cavity and the abdominal cavity by the lung cavity diaphragm, the upper sides of the two lungs in the lung cavity are the top a in the lung cavity, the lower sides of the two lungs in the lung cavity are the bottom B in the lung cavity, the lower side of the bottom B in the lung cavity is the lung cavity diaphragm, and the lung region and the heart are located between the top a in the lung cavity and the bottom B in the lung cavity. The first dynamic pressure at the top part A of the lung cavity and the second dynamic pressure at the bottom part B of the lung cavity can be detected in real time by means of a rib intubation and a pressure sensor (such as a pressure gauge).

In an embodiment of the present invention, the end points of the first interval are preset as the pressure values of the top a and the bottom B of the lung cavity at the end of expiration (the beginning of inspiration in the next phase). The end points of the two sides of the second interval are preset as the pressure values of the top A and the bottom B of the lung cavity when the normal person is at the end of inspiration (the next phase is the beginning of expiration). During the breathing process, the pressure value in the lung cavity is constantly changed; at the end of expiration, the pressure value of the bottom B in the lung cavity is greater than the pressure value of the top A in the lung cavity; and at the end of inspiration, the pressure value of the top A in the lung cavity is greater than the pressure value of the bottom B in the lung cavity.

In the embodiment of the present invention, the first dynamic pressure and the second dynamic pressure and the corresponding preset first interval and preset second interval need to be considered at the same time, and the positive pressure command or the negative pressure command is determined according to the relationship between the first dynamic pressure and the second dynamic pressure and the corresponding preset first interval and preset second interval.

In an embodiment of the present invention, the method for comparing the first dynamic pressure and the second dynamic pressure with a preset first interval and a preset second interval respectively to obtain a positive pressure command or a negative pressure command includes: if the first dynamic pressure is greater than or equal to the maximum critical value of the preset first interval and the second dynamic pressure is greater than or equal to the maximum critical value of the preset second interval, obtaining the positive pressure instruction; and if the first dynamic pressure is smaller than or equal to the minimum critical value of the preset first interval and the second dynamic pressure is smaller than or equal to the minimum critical value of the preset second interval, obtaining the negative pressure instruction.

In the present invention and its embodiments, the range of the preset first interval may be [ -2.8, -0.8], the range of the preset second interval may be [ -3.9, -0.2], the units of which are kPa, the above range is not limited specifically, and other ranges may be clinically set. If the first dynamic pressure is greater than or equal to-2.8, which is the maximum critical value of the preset first interval, and the second dynamic pressure is greater than or equal to 0.2, which is the maximum critical value of the preset second interval, it indicates that the patient is at the end of expiration and needs to start air extraction, and then the positive pressure instruction needs to be obtained; if the first dynamic pressure is less than or equal to-2.8, which is the minimum critical value of the preset first interval, and the second dynamic pressure is less than or equal to-3.9, which is the minimum critical value of the preset second interval, it indicates that the air is already at the end of air extraction and the exhalation needs to be started, and the negative pressure instruction needs to be obtained.

In the invention and the specific embodiment thereof, when the respirator is controlled to be switched from the air pumping state to the air inflation state according to the positive pressure instruction, the respirator generates air flow through positive pressure and causes air pumping. And when the respirator is controlled to be switched from an inflation state to an air extraction state according to the negative pressure instruction, the thorax and the lung collapse passively or the negative pressure generates expiration, and when the pressure in the lung cavity is reduced continuously, the respirator generates airflow through the positive pressure again and causes air extraction.

In summary, in the embodiment of the present disclosure, the set ventilation curve may be corrected by using the inspiration area of the patient, the air-extracting curve may be corrected according to the expiration curve of the patient, and the breathing control curve of the ventilator may be determined based on the corrected ventilation curve and the corrected inspiration curve obtained through the correction. The air supply and air exhaust control of the breathing machine can be adjusted according to the breathing state of the patient, and the breathing machine has better applicability.

In addition, because the preset first interval of the top in the lung cavity and the preset second interval of the bottom in the lung cavity are determined, the first dynamic pressure of the top in the lung cavity and the second dynamic pressure of the bottom in the lung cavity can be compared according to the preset first interval and the preset second interval to obtain a positive pressure instruction and a negative pressure instruction; the breathing machine starts to supply air (inflate) or starts to exhaust air according to the positive pressure instruction and the negative pressure instruction, and the conversion that the air exhaust state of the breathing machine is switched to the inflation state or the air exhaust state of the breathing machine is switched to the air exhaust state is completed. Thus, the consistency of the air supply and air exhaust of the respirator and the actual spontaneous respiration of the patient is improved.

It will be understood by those skilled in the art that in the method of the present invention, the order of writing the steps does not imply a strict order of execution and any limitations on the implementation, and the specific order of execution of the steps should be determined by their function and possible inherent logic.

The embodiment of the present disclosure also provides a device for determining a respiration control curve, including: the setting unit is used for setting a gas supply curve and a gas extraction curve; the measuring unit is used for measuring an inspiration curve and an expiration curve of a patient; the correction unit is used for correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve; correcting the air extraction curve according to the expiration curve to obtain a corrected air extraction curve; and the determining unit is used for determining a breathing control curve based on the correction air supply curve and the correction air exhaust curve.

In some embodiments, functions of or modules included in the apparatus provided in the embodiments of the present disclosure may be used to execute the method described in the above method embodiments, and specific implementation thereof may refer to the description of the above method embodiments, and for brevity, will not be described again here.

Embodiments of the present disclosure also provide a computer-readable storage medium having stored thereon computer program instructions, which when executed by a processor, implement the above-mentioned method. The computer readable storage medium may be a non-volatile computer readable storage medium.

An embodiment of the present disclosure further provides an electronic device, including: a processor; a memory for storing processor-executable instructions; wherein the processor is configured as the above method.

The electronic device may be provided as a terminal, server, or other form of device.

Fig. 2 illustrates a block diagram of an electronic device 800 in accordance with an embodiment of the disclosure. For example, the electronic device 800 may be a mobile phone, a computer, a digital broadcast terminal, a messaging device, a game console, a tablet device, a medical device, a fitness device, a personal digital assistant, or the like terminal.

Referring to fig. 2, electronic device 800 may include one or more of the following components: processing component 802, memory 804, power component 806, multimedia component 808, audio component 810, input/output (I/O) interface 812, sensor component 814, and communication component 816.

The processing component 802 generally controls overall operation of the electronic device 800, such as operations associated with display, telephone calls, data communications, camera operations, and recording operations. The processing components 802 may include one or more processors 820 to execute instructions to perform all or a portion of the steps of the methods described above. Further, the processing component 802 can include one or more modules that facilitate interaction between the processing component 802 and other components. For example, the processing component 802 can include a multimedia module to facilitate interaction between the multimedia component 808 and the processing component 802.

The memory 804 is configured to store various types of data to support operations at the electronic device 800. Examples of such data include instructions for any application or method operating on the electronic device 800, contact data, phonebook data, messages, pictures, videos, and so forth. The memory 804 may be implemented by any type or combination of volatile or non-volatile memory devices such as Static Random Access Memory (SRAM), electrically erasable programmable read-only memory (EEPROM), erasable programmable read-only memory (EPROM), programmable read-only memory (PROM), read-only memory (ROM), magnetic memory, flash memory, magnetic or optical disks.

The power supply component 806 provides power to the various components of the electronic device 800. The power components 806 may include a power management system, one or more power supplies, and other components associated with generating, managing, and distributing power for the electronic device 800.

The multimedia component 808 includes a screen that provides an output interface between the electronic device 800 and a user. In some embodiments, the screen may include a Liquid Crystal Display (LCD) and a Touch Panel (TP). If the screen includes a touch panel, the screen may be implemented as a touch screen to receive an input signal from a user. The touch panel includes one or more touch sensors to sense touch, slide, and gestures on the touch panel. The touch sensor may not only sense the boundary of a touch or slide action, but also detect the duration and pressure associated with the touch or slide operation. In some embodiments, the multimedia component 808 includes a front facing camera and/or a rear facing camera. The front camera and/or the rear camera may receive external multimedia data when the electronic device 800 is in an operation mode, such as a shooting mode or a video mode. Each front camera and rear camera may be a fixed optical lens system or have a focal length and optical zoom capability.

The audio component 810 is configured to output and/or input audio signals. For example, the audio component 810 includes a Microphone (MIC) configured to receive external audio signals when the electronic device 800 is in an operational mode, such as a call mode, a recording mode, and a voice recognition mode. The received audio signals may further be stored in the memory 804 or transmitted via the communication component 816. In some embodiments, audio component 810 also includes a speaker for outputting audio signals.

The I/O interface 812 provides an interface between the processing component 802 and peripheral interface modules, which may be keyboards, click wheels, buttons, etc. These buttons may include, but are not limited to: a home button, a volume button, a start button, and a lock button.

The sensor assembly 814 includes one or more sensors for providing various aspects of state assessment for the electronic device 800. For example, the sensor assembly 814 may detect an open/closed state of the electronic device 800, the relative positioning of components, such as a display and keypad of the electronic device 800, the sensor assembly 814 may also detect a change in the position of the electronic device 800 or a component of the electronic device 800, the presence or absence of user contact with the electronic device 800, orientation or acceleration/deceleration of the electronic device 800, and a change in the temperature of the electronic device 800. Sensor assembly 814 may include a proximity sensor configured to detect the presence of a nearby object without any physical contact. The sensor assembly 814 may also include a light sensor, such as a CMOS or CCD image sensor, for use in imaging applications. In some embodiments, the sensor assembly 814 may also include an acceleration sensor, a gyroscope sensor, a magnetic sensor, a pressure sensor, or a temperature sensor.

The communication component 816 is configured to facilitate wired or wireless communication between the electronic device 800 and other devices. The electronic device 800 may access a wireless network based on a communication standard, such as WiFi, 2G or 3G, or a combination thereof. In an exemplary embodiment, the communication component 816 receives a broadcast signal or broadcast related information from an external broadcast management system via a broadcast channel. In an exemplary embodiment, the communication component 816 further includes a Near Field Communication (NFC) module to facilitate short-range communications. For example, the NFC module may be implemented based on Radio Frequency Identification (RFID) technology, infrared data association (IrDA) technology, Ultra Wideband (UWB) technology, Bluetooth (BT) technology, and other technologies.

In an exemplary embodiment, the electronic device 800 may be implemented by one or more Application Specific Integrated Circuits (ASICs), Digital Signal Processors (DSPs), Digital Signal Processing Devices (DSPDs), Programmable Logic Devices (PLDs), Field Programmable Gate Arrays (FPGAs), controllers, micro-controllers, microprocessors or other electronic components for performing the above-described methods.

In an exemplary embodiment, a non-transitory computer-readable storage medium, such as the memory 804, is also provided that includes computer program instructions executable by the processor 820 of the electronic device 800 to perform the above-described methods.

Fig. 3 shows a block diagram of an electronic device 1900 according to an embodiment of the disclosure. For example, the electronic device 1900 may be provided as a server. Referring to fig. 3, electronic device 1900 includes a processing component 1922 further including one or more processors and memory resources, represented by memory 1932, for storing instructions, e.g., applications, executable by processing component 1922. The application programs stored in memory 1932 may include one or more modules that each correspond to a set of instructions. Further, the processing component 1922 is configured to execute instructions to perform the above-described method.

The electronic device 1900 may also include a power component 1926 configured to perform power management of the electronic device 1900, a wired or wireless network interface 1950 configured to connect the electronic device 1900 to a network, and an input/output (I/O) interface 1958. The electronic device 1900 may operate based on an operating system stored in memory 1932, such as Windows Server, Mac OS XTM, UnixTM, LinuxTM, FreeBSDTM, or the like.

In an exemplary embodiment, a non-transitory computer readable storage medium, such as the memory 1932, is also provided that includes computer program instructions executable by the processing component 1922 of the electronic device 1900 to perform the above-described methods.

The present disclosure may be systems, methods, and/or computer program products. The computer program product may include a computer-readable storage medium having computer-readable program instructions embodied thereon for causing a processor to implement various aspects of the present disclosure.

The computer readable storage medium may be a tangible device that can hold and store the instructions for use by the instruction execution device. The computer readable storage medium may be, for example, but not limited to, an electronic memory device, a magnetic memory device, an optical memory device, an electromagnetic memory device, a semiconductor memory device, or any suitable combination of the foregoing. More specific examples (a non-exhaustive list) of the computer readable storage medium would include the following: a portable computer diskette, a hard disk, a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), a Static Random Access Memory (SRAM), a portable compact disc read-only memory (CD-ROM), a Digital Versatile Disc (DVD), a memory stick, a floppy disk, a mechanical coding device, such as punch cards or in-groove projection structures having instructions stored thereon, and any suitable combination of the foregoing. Computer-readable storage media as used herein is not to be construed as transitory signals per se, such as radio waves or other freely propagating electromagnetic waves, electromagnetic waves propagating through a waveguide or other transmission medium (e.g., optical pulses through a fiber optic cable), or electrical signals transmitted through electrical wires.

The computer-readable program instructions described herein may be downloaded from a computer-readable storage medium to a respective computing/processing device, or to an external computer or external storage device via a network, such as the internet, a local area network, a wide area network, and/or a wireless network. The network may include copper transmission cables, fiber optic transmission, wireless transmission, routers, firewalls, switches, gateway computers and/or edge servers. The network adapter card or network interface in each computing/processing device receives computer-readable program instructions from the network and forwards the computer-readable program instructions for storage in a computer-readable storage medium in the respective computing/processing device.

The computer program instructions for carrying out operations of the present disclosure may be assembler instructions, Instruction Set Architecture (ISA) instructions, machine-related instructions, microcode, firmware instructions, state setting data, or source or object code written in any combination of one or more programming languages, including an object oriented programming language such as Smalltalk, C + + or the like and conventional procedural programming languages, such as the "C" programming language or similar programming languages. The computer-readable program instructions may execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer or entirely on the remote computer or server. In the case of a remote computer, the remote computer may be connected to the user's computer through any type of network, including a Local Area Network (LAN) or a Wide Area Network (WAN), or the connection may be made to an external computer (for example, through the Internet using an Internet service provider). In some embodiments, the electronic circuitry that can execute the computer-readable program instructions implements aspects of the present disclosure by utilizing the state information of the computer-readable program instructions to personalize the electronic circuitry, such as a programmable logic circuit, a Field Programmable Gate Array (FPGA), or a Programmable Logic Array (PLA).

Various aspects of the present disclosure are described herein with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems) and computer program products according to embodiments of the disclosure. It will be understood that each block of the flowchart illustrations and/or block diagrams, and combinations of blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer-readable program instructions.

These computer-readable program instructions may be provided to a processor of a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions/acts specified in the flowchart and/or block diagram block or blocks. These computer-readable program instructions may also be stored in a computer-readable storage medium that can direct a computer, programmable data processing apparatus, and/or other devices to function in a particular manner, such that the computer-readable medium storing the instructions comprises an article of manufacture including instructions which implement the function/act specified in the flowchart and/or block diagram block or blocks.

The computer readable program instructions may also be loaded onto a computer, other programmable data processing apparatus, or other devices to cause a series of operational steps to be performed on the computer, other programmable apparatus or other devices to produce a computer implemented process such that the instructions which execute on the computer, other programmable apparatus or other devices implement the functions/acts specified in the flowchart and/or block diagram block or blocks.

The flowchart and block diagrams in the figures illustrate the architecture, functionality, and operation of possible implementations of systems, methods and computer program products according to various embodiments of the present disclosure. In this regard, each block in the flowchart or block diagrams may represent a module, segment, or portion of instructions, which comprises one or more executable instructions for implementing the specified logical function(s). In some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown in succession may, in fact, be executed substantially concurrently, or the blocks may sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams and/or flowchart illustration, and combinations of blocks in the block diagrams and/or flowchart illustration, can be implemented by special purpose hardware-based systems which perform the specified functions or acts, or combinations of special purpose hardware and computer instructions.

Having described embodiments of the present disclosure, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the disclosed embodiments. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen in order to best explain the principles of the embodiments, the practical application, or improvements made to the technology in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. A method of determining a breathing control curve, comprising:

2. The method of claim 1, wherein:

the method of setting an inspiratory curve and measuring an inspiratory curve of a patient comprises: respectively setting a set air supply speed curve and a set air supply flow curve in the set air supply curve; measuring the inspiratory speed and inspiratory capacity of the patient; respectively determining an inspiration speed curve and an inspiration flow curve in the inspiration curve according to the inspiration speed and the inspiration amount;

and/or the presence of a gas in the interior of the container,

3. The method of claim 2, wherein:

the method for correcting the air supply curve according to the air suction curve to obtain a corrected air supply curve comprises the following steps:

and/or the presence of a gas in the interior of the container,

4. The method of claim 3, wherein:

the method for determining the air supply speed correction coefficient according to the air suction speed curve and the set air supply speed curve comprises the following steps:

and/or the presence of a gas in the interior of the container,

5. The method according to claim 3 or 4, wherein the method of correcting the delivery curve according to the inhalation curve to obtain a corrected delivery curve, and/or the method of correcting the pumping curve according to the exhalation curve to obtain a corrected pumping curve further comprises:

determining a lung injury coefficient according to the chest image data;

6. The method of claim 5, wherein:

the method for determining the lung injury coefficient according to the chest image comprises the following steps:

determining whether a lung injury exists according to the chest image data;

wherein the initial value of the lung injury coefficient is 1;

and/or the presence of a gas in the interior of the container,

7. The method of claim 6, wherein the step of correcting the initial value to obtain a corrected lung injury coefficient if lung injury exists comprises:

determining a volume of the lung lesion and a volume of both lungs;

wherein the corrected lung injury coefficient is less than 1.

8. An apparatus for determining a breathing control curve, comprising:

9. An electronic device, comprising:

a processor;

a memory for storing processor-executable instructions;

wherein the processor is configured to invoke the memory-stored instructions to perform the method of any of claims 1 to 7.

10. A computer readable storage medium having computer program instructions stored thereon, which when executed by a processor implement the method of any one of claims 1 to 7.