CN111904613A - Puncture positioning grid for image guidance - Google Patents
Puncture positioning grid for image guidance Download PDFInfo
- Publication number
- CN111904613A CN111904613A CN202010874634.5A CN202010874634A CN111904613A CN 111904613 A CN111904613 A CN 111904613A CN 202010874634 A CN202010874634 A CN 202010874634A CN 111904613 A CN111904613 A CN 111904613A
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- China
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- base layer
- printing stock
- stock base
- grid
- puncture positioning
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- 238000007639 printing Methods 0.000 claims abstract description 29
- 239000000758 substrate Substances 0.000 claims abstract description 12
- 229910052751 metal Inorganic materials 0.000 claims abstract description 9
- 239000002184 metal Substances 0.000 claims abstract description 9
- 229910052688 Gadolinium Inorganic materials 0.000 claims abstract description 5
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000011159 matrix material Substances 0.000 claims abstract description 5
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 4
- 150000002736 metal compounds Chemical class 0.000 claims description 8
- 230000005298 paramagnetic effect Effects 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 5
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 3
- 239000002872 contrast media Substances 0.000 claims description 3
- 229910052740 iodine Inorganic materials 0.000 claims description 3
- 239000011630 iodine Substances 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 2
- 238000013170 computed tomography imaging Methods 0.000 claims description 2
- 150000002739 metals Chemical class 0.000 claims description 2
- 238000010023 transfer printing Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 206010011409 Cross infection Diseases 0.000 abstract description 4
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 4
- 239000000843 powder Substances 0.000 abstract description 2
- 150000002632 lipids Chemical class 0.000 abstract 1
- 230000005291 magnetic effect Effects 0.000 description 3
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 238000011298 ablation treatment Methods 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229940044350 gadopentetate dimeglumine Drugs 0.000 description 1
- LGMLJQFQKXPRGA-VPVMAENOSA-K gadopentetate dimeglumine Chemical group [Gd+3].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O LGMLJQFQKXPRGA-VPVMAENOSA-K 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000013188 needle biopsy Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3983—Reference marker arrangements for use with image guided surgery
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention discloses a puncture positioning grid for image guidance, which is characterized in that: the CT-MRI developing device comprises a printing stock base layer, wherein a plurality of grid bars for CT and MRI development are arranged on the printing stock base layer, and the printing stock base layer is made of thin and semitransparent water-soluble transfer paper or semitransparent non-woven fabric with high adsorbability and flexibility; the main components of the grid bars comprise high-density metal powder, gadolinium, lipid and an oily color solution matrix, and the grid bars are arranged on the surface of a printing stock base layer in a printing mode. The grid bars are conveniently printed on the flexible substrate with strong adsorbability, can be developed on CT and MRI at the same time, have low manufacturing cost, can be used as a disposable article, and reduce cross infection.
Description
Technical Field
The invention relates to a clinical puncture positioning technology, in particular to a puncture positioning grid for image guidance.
Background
Due to high spatial resolution and no bone and air artifact interference, imaging techniques, including CT and MRI, are widely used in various image guidance tools for percutaneous needle procedures, such as needle biopsy, abscess drainage, and various tumor ablation treatments. Although the optimal layer of the puncture lesion can be selected according to the position of the bed on which the CT and MRI tomographic images are located, the exact physical position of the puncture site cannot be determined. Therefore, before scanning, a positioning grid is often required to be placed on the body surface of the puncture area so as to accurately position the needle inserting point of the puncture needle.
Currently, the most widely used positioning grid in clinical practice is mostly made by a clinician by adhering multiple sections of metal wires (steel wires or guide wires for intervention) in parallel by using an adhesive tape. Such simple positioning grids, although inexpensive, require temporary fabrication prior to lancing, are time consuming and inaccurate. Dedicated metal grid price is very expensive, uses repeatedly the risk that causes cross infection in the hospital between the different patients also to improve greatly, in addition because it adopts hard material, so it is not good with patient's skin laminating situation, the drift that appears the position when leading to confirming the puncture point, calculates and brings the mistake for subsequent accurate puncture. In addition, such a grid made of metal material can only be used in CT, and a positioning grid used in magnetic resonance is not available in the market at present, because the technical principles of MRI and CT imaging are completely different.
Disclosure of Invention
The invention aims to provide a puncture positioning grid for image guidance, which is compatible with CT and MRI and has lower manufacturing cost.
In order to solve the technical problems, the invention adopts the technical scheme that: a puncture positioning grid for image guidance comprises a printing stock base layer, wherein a plurality of grid bars for CT and MRI development are arranged on the printing stock base layer, and the printing stock base layer is made of flexible materials; the main components of the grid bars comprise a high-density metal compound, a paramagnetic substance, triglyceride and an oily color solution matrix, wherein the mass ratio of the high-density metal compound to the paramagnetic substance to the triglyceride is 3: 0.8-1.2, and the grid bars are arranged on the surface of a substrate in a printing stock in a printing mode; high density metal refers to metals having an atomic number greater than 53.
Furthermore, the printing stock base layer is made of thin and flexible semitransparent water-soluble transfer printing paper or semitransparent non-woven fabric with adsorbability, and ink of the oily marking pen can penetrate through the printing stock base layer and enter the surface of skin.
Furthermore, an organic iodine contrast agent is mixed in the grid bars.
Further, the paramagnetic substance is gadopentetate dimeglumine.
Furthermore, the surface of the substrate contacted with the skin has self-adhesion and can be adhered to the surface of the skin.
The technical scheme shows that the invention has the following advantages: the grid bars are conveniently printed on the flexible substrate with strong adsorbability, can be developed on CT and MRI simultaneously, have self-adhesion, can be well attached to the body surface of a patient, and reduce the drift of the mark points. The manufacturing cost is low, so that the disposable diaper can be used as a disposable article, and the cross infection is reduced.
Drawings
FIG. 1 is a schematic structural diagram of the present invention.
Detailed Description
The following detailed description of embodiments of the invention refers to the accompanying drawings.
The invention discloses a puncture positioning grid for image guidance, which comprises a printing stock base layer 1. The substrate of the printing stock is made of thin and flexible semitransparent water-soluble transfer paper or semitransparent non-woven fabric with adsorbability, and ink of the oily marking pen can penetrate through the substrate of the printing stock to enter the surface of skin. The flexible substrate can be attached to the skin by the base layer of the printing stock, the base layer of the printing stock is attached to the skin, the position deviation cannot occur when the puncture point is determined, and the puncture point can be accurately calculated. The substrate with adsorbability can be penetrated into the surface of the skin by ink of the oily marking pen through the substrate of the printing stock, so that the puncture points can be conveniently marked.
The grid bars 2 used for CT and MRI development are arranged on a substrate of a printing stock, wherein the main components of each grid bar comprise high-density metal compound powder (or high-density metal compound solvent), gadolinium (or gadolinium pentagraph acid glucamine), triglyceride and an oily color solution matrix, the mass ratio of the components is 3: 0.8-1.2, and the material is uniformly blended by the amount of the oily color solution matrix. Wherein the high-density metal refers to stable high-density metal with atomic number larger than 53, the high-density metal compound can be developed on CT, and barium sulfate can be used as the high-density metal compound. Gadolinium is able to develop a high signal at magnetic resonance T1 WI. Triglycerides develop a high signal at magnetic resonance T2.
The materials are prepared into slurry according to the proportion to be used as raw materials of the grid bars, and the slurry is printed on the surface of a base layer of a printing stock in a printing mode to form the grid bars.
In addition, each positioning grid can be provided with a disposable sterile package which can be applied in a sterile environment.
In addition, a few iodine contrast agents can be added into the grid.
The grid bars are conveniently printed on the flexible substrate with strong adsorbability, can be developed on CT and MRI simultaneously, have self-adhesion, can be well attached to the body surface of a patient, and reduce the drift of the mark points. The manufacturing cost is low, so that the disposable diaper can be used as a disposable article, and the cross infection is reduced.
Claims (5)
1. A puncture positioning grid for image guidance, which is characterized in that: the CT imaging system comprises a printing stock base layer, wherein a plurality of grid bars for CT and MRI development are arranged on the printing stock base layer, and the printing stock base layer is made of flexible materials; the main components of the grid bars comprise a high-density metal compound, a paramagnetic substance, triglyceride and an oily color solution matrix, wherein the mass ratio of the high-density metal compound to the paramagnetic substance to the triglyceride is 3: 0.8-1.2, and the grid bars are arranged on the surface of a substrate in a printing stock in a printing mode; high density metal refers to metals having an atomic number greater than 53.
2. The image-guided puncture positioning grid according to claim 1, wherein: the printing stock base layer is made of thin and flexible semitransparent water-soluble transfer printing paper or semitransparent non-woven fabric with adsorbability, and ink of the oily marking pen can penetrate through the printing stock base layer and enter the surface of skin.
3. The image-guided puncture positioning grid according to claim 1, wherein: the grid is also mixed with an organic iodine contrast agent.
4. The image-guided puncture positioning grid according to claim 1, wherein: the paramagnetic substance is gadolinium pentagraph acid glucamine.
5. The image-guided puncture positioning grid according to claim 1, wherein: the surface of the printing stock base layer, which is contacted with the skin, has self-adhesion and can be stuck on the surface of the skin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010874634.5A CN111904613A (en) | 2020-08-27 | 2020-08-27 | Puncture positioning grid for image guidance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010874634.5A CN111904613A (en) | 2020-08-27 | 2020-08-27 | Puncture positioning grid for image guidance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111904613A true CN111904613A (en) | 2020-11-10 |
Family
ID=73278768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010874634.5A Pending CN111904613A (en) | 2020-08-27 | 2020-08-27 | Puncture positioning grid for image guidance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111904613A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5052035A (en) * | 1989-11-02 | 1991-09-24 | Webb Research Ii Corporation | Image location marking devices for radiographs, method of making and methods of use |
| CN102028550A (en) * | 2011-01-05 | 2011-04-27 | 武汉维斯第医用科技有限公司 | Clinical medicinal patch with developing coordinates |
| US20120163553A1 (en) * | 2010-12-27 | 2012-06-28 | Analogic Corporation | Three-dimensional metal printing |
| CN104114093A (en) * | 2011-12-08 | 2014-10-22 | 帕克实验室股份有限公司 | Biopsy grid |
| CN205458730U (en) * | 2016-01-27 | 2016-08-17 | 王小楠 | Low -cost medical ray location film |
| CN110664494A (en) * | 2019-09-25 | 2020-01-10 | 温州医科大学附属第一医院 | Ablation puncture auxiliary patch |
| CN110840573A (en) * | 2019-11-28 | 2020-02-28 | 徐州英杰医疗科技有限公司 | Contrast material, developing adhesive tape external positioning plaster and production process thereof |
| CN211213153U (en) * | 2019-12-10 | 2020-08-11 | 重庆市铜梁区人民医院 | Body surface positioning patch for nuclear magnetic resonance examination |
-
2020
- 2020-08-27 CN CN202010874634.5A patent/CN111904613A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5052035A (en) * | 1989-11-02 | 1991-09-24 | Webb Research Ii Corporation | Image location marking devices for radiographs, method of making and methods of use |
| US20120163553A1 (en) * | 2010-12-27 | 2012-06-28 | Analogic Corporation | Three-dimensional metal printing |
| CN102028550A (en) * | 2011-01-05 | 2011-04-27 | 武汉维斯第医用科技有限公司 | Clinical medicinal patch with developing coordinates |
| CN104114093A (en) * | 2011-12-08 | 2014-10-22 | 帕克实验室股份有限公司 | Biopsy grid |
| CN205458730U (en) * | 2016-01-27 | 2016-08-17 | 王小楠 | Low -cost medical ray location film |
| CN110664494A (en) * | 2019-09-25 | 2020-01-10 | 温州医科大学附属第一医院 | Ablation puncture auxiliary patch |
| CN110840573A (en) * | 2019-11-28 | 2020-02-28 | 徐州英杰医疗科技有限公司 | Contrast material, developing adhesive tape external positioning plaster and production process thereof |
| CN211213153U (en) * | 2019-12-10 | 2020-08-11 | 重庆市铜梁区人民医院 | Body surface positioning patch for nuclear magnetic resonance examination |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201110 |