CN111887173A

CN111887173A - Cross labyrinth device

Info

Publication number: CN111887173A
Application number: CN202010567571.9A
Authority: CN
Inventors: 郭琼; 洪育川; 周辛夷; 肖倩; 谢丽; 徐锡荣; 屠洁
Original assignee: Shenzhen Institute of Advanced Technology of CAS
Current assignee: Shenzhen Institute of Advanced Technology of CAS
Priority date: 2020-06-19
Filing date: 2020-06-19
Publication date: 2020-11-06

Abstract

The application provides a cross labyrinth device. The device comprises a cross maze main body, a sensor and a controller; the sensor is arranged on the cross maze main body and used for sensing a position sensing signal of a target to be measured on the cross maze main body in real time; the controller is connected with the sensor and used for acquiring the position sensing signal so as to determine the position or the motion track of the target to be detected based on the position sensing signal. The device can acquire the position information of the target to be detected on the cross maze main body in real time, and can check and solve the problems encountered in the experimental process in time.

Description

Cross labyrinth device

Technical Field

The invention relates to the technical field of life science, in particular to a cross labyrinth device.

Background

The elevated plus maze is a classic behavioral experiment for anxiety and depression research, and is widely applied to the research of multiple disciplines such as neurobiology, pharmacology, animal psychology, toxicology and the like; however, in the experimental process, the position information of the target to be measured in the elevated plus maze is often required to be acquired.

At present, the motion condition of a target to be detected in an elevated plus maze is generally recorded by a camera, and then after an experiment is finished, a video is analyzed by software to obtain the position information of the target to be detected; however, the method needs to analyze the obtained video after the experiment is finished to obtain the position information of the target to be detected, so that the obtained data has certain hysteresis, and the problems encountered in the experiment process cannot be timely perceived and solved.

Disclosure of Invention

The application provides a cross maze device, the device can acquire the positional information of the target of awaiting measuring on the cross maze main part in real time, and can in time look over and solve the problem that meets in the experimentation.

In order to solve the technical problem, the application adopts a technical scheme that: there is provided a plus labyrinth device including a plus labyrinth body, a sensor, and a controller. The sensor is arranged on the cross maze main body and used for sensing a position sensing signal of a target to be measured on the cross maze main body in real time; the controller is connected with the sensor and used for acquiring the position sensing signal so as to determine the position or the motion track of the target to be detected based on the position sensing signal.

The sensor is laid on the upper surface of the cross maze main body and used for detecting whether the target to be detected is located at the position of the sensor or not according to the change of data of the sensor so as to sense the position sensing signal of the target to be detected on the cross maze main body in real time.

The sensors are a plurality of pressure sensors which are paved on the upper surface of the cross labyrinth main body at intervals and arranged at the edge of the cross labyrinth main body; the pressure sensor detects whether the current pressure data of the pressure sensor changes or not, and when the pressure data of the pressure sensor changes, the target to be detected is located at the current position of the pressure sensor.

Wherein the pressure sensor comprises a semiconductor pressure sensor; the cross maze main part is including opening the arm and closing the arm, open the arm and/or close the arm and constitute by a plurality of independent setting's platelet, and every all be provided with one on the platelet pressure sensor.

The sensors are a plurality of temperature sensors which are arranged on the upper surface of the cross maze main body at intervals and arranged at the edge of the cross maze main body; the temperature sensor detects whether the current temperature data of the temperature sensor changes or not, and determines that the target to be detected is located at the current position of the temperature sensor when the temperature data of the temperature sensor changes.

The crisscross labyrinth device further comprises an analog-to-digital converter, wherein the analog-to-digital converter is respectively connected with the sensor and the controller and is used for receiving and converting the position sensing signals detected by the sensor and sending the converted position sensing signals to the controller.

The crisscross labyrinth device further comprises a communication circuit, and the communication circuit is connected with the controller and used for transmitting the position or the motion track of the target to be detected to a display for displaying.

Wherein the communication circuit comprises any one of a Bluetooth communication circuit, a Wi-Fi communication circuit, a short-range wireless communication circuit, an ultra-wideband communication circuit and a purple peak network communication circuit.

Wherein, the display is a computer and/or a mobile phone.

Wherein, the controller is a singlechip with the function of Bluetooth wireless transmission.

According to the cross maze device, the cross maze main body is arranged, so that a target to be detected can move on the cross maze main body, and an anxiety and depression research experiment is carried out; meanwhile, a sensor is arranged on the cross maze main body to sense a position sensing signal of the target to be measured on the cross maze main body in real time; in addition, the controller is arranged and connected with the sensor to acquire a position sensing signal sensed by the sensor, and the position or the motion track of the target to be detected on the cross maze main body is determined based on the position sensing signal, so that the position information of the target to be detected on the cross maze main body is acquired in real time; compared with the prior art that the obtained video is analyzed after the experiment is finished to obtain the position information of the target to be tested, the device can be used for performing anxiety and depression research experiments, can obtain the position information of the target to be tested in real time in the experiment process, and can check and solve the problems encountered in the experiment process in real time; in addition, a video does not need to be shot by using a camera, and the step of analyzing the video after the experiment is omitted, so that the experiment time can be saved, and the data accuracy can be improved.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:

FIG. 1 is a schematic structural view of a plus labyrinth device according to an embodiment of the present disclosure;

FIG. 2 is a schematic structural diagram of a cross-shaped labyrinth main body according to an embodiment of the present application;

fig. 3 is a schematic structural view of a plus labyrinth device according to another embodiment of the present application.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "first", "second" and "third" in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any indication of the number of technical features indicated. Thus, a feature defined as "first," "second," or "third" may explicitly or implicitly include at least one of the feature. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless explicitly specifically limited otherwise. All directional indications (such as up, down, left, right, front, and rear … …) in the embodiments of the present application are only used to explain the relative positional relationship between the components, the movement, and the like in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indication is changed accordingly. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

The present application will be described in detail with reference to the accompanying drawings and examples.

Referring to fig. 1 and fig. 2, in which, fig. 1 is a schematic structural diagram of a plus labyrinth device provided in an embodiment of the present application; FIG. 2 is a schematic structural diagram of a cross-shaped labyrinth main body according to an embodiment of the present application; in the present embodiment, a plus labyrinth device 10 is provided, the plus labyrinth device 10 may be used for performing an anxiety and depression research experiment, and specifically, the plus labyrinth device 10 includes a plus labyrinth body 11, a sensor 12 and a controller 13.

The cross maze main body 11 is generally far away from the ground, which is equivalent to a person standing on a cliff and standing on the open arm 111, so that the object to be measured generates fear and uneasy mind. For example, rodents tend to move in the closed arm 112 due to darkness but move in the open arm 111 due to curiosity and exploratory, which conflicting behavioral tendencies create anxiety in the animal. Based on this, the plus-maze main body 11 is generally used for performing anxiety and depression research experiments, so that the object to be measured can move on the plus-maze main body 11 when performing the anxiety and depression research experiments; the target to be detected may be a rodent.

In particular, the structure of the plus-maze main body 11 can be seen in fig. 2, which specifically includes a central area 113 and four side arms; two of the four side walls are open arms 111, the other two are closed arms 112, the two open arms 111 are arranged oppositely, and the two closed arms 112 are arranged oppositely; specifically, the opening arm 111 specifically includes a movable plate for movement of the target to be measured; the closing arm 112 specifically includes a movable plate for moving the target to be measured and a baffle vertically disposed at two sides of the movable plate, so that the target to be measured can have a certain safety sense when moving on the closing arm 112 through the baffle.

In one embodiment, the two opening arms 111 are integrally formed, the two closing walls 112 are integrally formed, and the length of the opening arms 111 and the closing walls 112 may be 25cm x 5 cm.

Of course, in other embodiments, the maze main body 11 can be other elevated maze in the prior art, and this embodiment is not limited thereto.

The sensor 12 is arranged on the cross maze main body 11 and is used for sensing a position sensing signal of the target to be measured on the cross maze main body 11 in real time so as to acquire the position information of the target to be measured in real time.

Specifically, the sensor 12 may be laid on the upper surface of the cross labyrinth main body 11, and is configured to detect whether there is a position of the target to be detected at the current position of the sensor 12 according to a change of the data of the sensor 12, and then sense a position sensing signal of the target to be detected on the cross labyrinth main body 11 in real time. Specifically, the sensors 12 may be disposed on the upper surface of the plus labyrinth main body 11 at intervals according to the range in which the sensors can sense themselves, so as to improve the detection accuracy of the sensors 12; in an embodiment, the sensor 12 may be disposed at the edge of the maze main body 11 to avoid the sensor 12 from obstructing the movement of the object to be measured.

In an embodiment, the sensor 12 may be a plurality of pressure sensors, and the plurality of pressure sensors may be laid on the upper surface of the plus labyrinth main body 11 at intervals and disposed at the edge of the plus labyrinth main body 11; the spacing distance may be specifically set according to an actual range that can be sensed by the pressure sensor itself, which is not limited in this embodiment; specifically, the pressure sensor detects whether the current pressure data changes, and when the pressure sensor detects that the current pressure data changes, the position of a target to be detected at the current pressure sensor is determined; and when the pressure sensor does not detect that the current pressure data of the pressure sensor changes, determining that the target to be measured is not located at the current position of the pressure sensor. It can be understood that when the object to be measured passes through a certain position of the plus labyrinth main body 11, the object to be measured generates a pressure on the plus labyrinth main body 11 under the action of its gravity, and the pressure sensor disposed at the certain position senses the pressure and forms a new pressure data, and if the pressure data is changed compared with the previous pressure data, it is determined that the object to be measured passes through the certain position and sends a position sensing signal of the current object to be measured on the plus labyrinth main body 11 to the controller 13.

In an embodiment, the open arm 111 and the close arm 112 of the maze main body 11 may be both composed of a plurality of small plates which are independently arranged, and each small plate is provided with a pressure sensor, so as to sense a position sensing signal of an object to be measured on the maze main body 11 in real time through the pressure sensor corresponding to the small plate; wherein, because each platelet independently sets up, pressure sensor on every platelet only can respond to the target of awaiting measuring on the current platelet, has avoided a plurality of pressure sensors to sense the problem of the target of awaiting measuring simultaneously and has taken place, and can respond to the position sensing signal of the target of awaiting measuring on cross maze main part 11 through the pressure sensor of a plurality of independent settings more accurately.

Specifically, if the target to be detected is located on two small plates, and the pressure sensors on the two small plates have a pressure sensing value at this time, the position corresponding to the pressure sensor with the largest pressure sensing value is taken as the current position of the target to be detected.

Specifically, the small plates are the same in size, and the pressure sensor is specifically arranged in the middle of the small plates, so that the sensing precision is improved.

Furthermore, an image acquisition device can be arranged at the same time, and is used for acquiring the image of the target to be detected on the cross maze main body 11 in real time and processing the image to acquire the position or the action track of the target to be detected on the cross maze main body 11; thereby further improving the accuracy of obtaining the position or action track of the target to be measured. For a specific implementation process of processing the image to obtain the position or the action track of the target to be detected on the plus maze main body 11, reference may be made to a specific implementation process of processing the image to obtain the position or the action track of the target in the image in the prior art, and the same or similar technical effects may be achieved, which is not described herein again.

In one embodiment, to ensure that the pressure sensor can sense objects of different weights, the pressure sensor may include a relatively sensitive semiconductor pressure sensor.

In another embodiment, the sensor 12 may also be a plurality of temperature sensors, and the plurality of temperature sensors are arranged on the upper surface of the plus labyrinth main body 11 at intervals and arranged at the edge of the plus labyrinth main body 11; the temperature sensor detects whether the current temperature data changes, and when the temperature sensor detects that the temperature data of the temperature sensor changes, the target to be detected is located at the position of the current temperature sensor; and when the temperature sensor does not detect that the temperature data of the temperature sensor changes, determining that the target to be measured is not located at the current position of the temperature sensor.

In particular, the temperature sensor may be a non-contact temperature sensor.

It can be understood that the object to be measured has a certain body temperature, when the object to be measured passes through a certain position of the plus maze main body 11, the temperature sensor arranged at the position can sense the body temperature of the object to be measured and acquire the body temperature data, and if the sensed body temperature data changes compared with the initial temperature data, the position of the object to be measured passing through the current temperature sensor is determined and a position sensing signal of the current object to be measured on the plus maze main body 11 is sent to the controller 13.

Specifically, in order to improve the detection accuracy of the temperature sensor and prevent the sensor from obstructing the movement of the object to be measured, a sensitivity-adjustable, portable, and ultra-small temperature sensor, such as model P0.410.2L0100, may be selected.

In one embodiment, in order to improve the detection accuracy, a pressure sensor and a temperature sensor may be arranged on the upper surface of the plus labyrinth body 11 at the same time; specifically, the pressure sensor and the temperature sensor may be disposed at two sides of the opening arm 111 and the closing arm 112, so that the object to be detected is detected by the pressure sensor and the temperature sensor when the object to be detected passes through the positions corresponding to the pressure sensor and the temperature sensor.

In another embodiment, a plurality of pressure sensors distributed at intervals can be oppositely arranged on two sides of the opening arm 111, and a plurality of temperature sensors distributed at intervals can be oppositely arranged on two sides of the closing arm 112; this embodiment is not limited in this regard.

Of course, in other embodiments, an infrared sensor may also be used, which is not limited in this embodiment as long as the target to be detected can be sensed when the target to be detected passes through the corresponding position.

The following describes in detail the procedure of the anxiety test using the plus maze device 10.

Specifically, in the experimental process, a target to be tested (for example, a mouse) is placed on the cross maze main body 11 to move freely, and when the mouse moves in the closed arm 112, the mouse is relatively in a safe environment and is relatively safe; however, the mouse's instinct drives the mouse to explore, so the mouse also moves from the closed arm 112 to the open arm 111; when the mouse moves to the arm opening 111, the mouse is equivalent to a human moving on the edge of the cliff, so that a fear mind can be generated; normal mice go to the open arm 111 for exploration even if feared, while anxiety or depressed mice remain confined to the closed arm 112 for risk avoidance and do not want to go to the open arm 111 for exploration.

Based on the above principle, in the specific embodiment, the mouse is generally placed on the cross maze body 11 to freely move for a preset time, for example, freely move for 5 minutes; then, a position sensing signal of the mouse on the plus maze main body 11 is sensed in real time through a sensor, and the position sensing signal is acquired through a controller connected with the sensor, so that the position or the motion track of the mouse is determined based on the position sensing signal, the time that the mouse stays at the opening arm 111 and the closing arm 112 respectively and the times of opening the arm 111 from the closing arm 112 are recorded, and the anxiety experiment of the mouse is completed.

The controller 13 is connected to the sensor 12, and is configured to acquire a position sensing signal sensed by the sensor 12, so as to determine a position or a motion trajectory of the target to be detected based on the position sensing signal. In one embodiment, the controller 13 may be a single chip with bluetooth wireless transmission function.

In the plus maze device 10 provided by the embodiment, the plus maze main body 11 is arranged, so that the target to be measured can move on the plus maze main body 11, and an anxiety and depression research experiment is performed; meanwhile, a sensor 12 is arranged on the cross maze main body 11 to sense a position sensing signal of the target to be measured on the cross maze main body 11 in real time; in addition, the controller 13 is arranged, and the controller 13 is connected with the sensor 12 to obtain a position sensing signal sensed by the sensor 12, and the position or the motion track of the target to be detected on the cross maze main body 11 is determined based on the position sensing signal, so that the position information of the target to be detected on the cross maze main body 11 is obtained in real time; compared with the prior art that the obtained video is analyzed after the experiment is finished to obtain the position information of the target to be tested, the device 10 not only can be used for performing anxiety and depression research experiments, but also can be used for obtaining the position information of the target to be tested in real time in the experiment process, and meanwhile, can be used for checking and solving the problems encountered in the experiment process in real time; in addition, a video does not need to be shot by using a camera, and the step of analyzing the video after the experiment is omitted, so that the experiment time can be saved, and the data accuracy can be improved.

Referring to fig. 3, fig. 3 is a schematic structural diagram of a plus labyrinth device according to another embodiment of the present application. In the present embodiment, there is provided a plus labyrinth device 20, and the plus labyrinth device 20 includes a plus labyrinth body 21, a sensor 22, an analog-to-digital converter 23, a communication circuit 24, and a controller 25.

The cross maze main body 21 is used for allowing a target to be tested to freely move on the surface of the cross maze main body during an anxiety experiment; the specific structure and function of the cross-shaped labyrinth main body 11 are the same as or similar to those of the cross-shaped labyrinth main body 11 in the above embodiments, and the same or similar technical effects can be achieved.

The sensor 22 can be laid on the upper surface of the cross maze main body 21 and used for detecting whether a target to be detected is located at the position of the sensor 22 according to the change of the data of the sensor 22, and then sensing a position sensing signal of the target to be detected on the cross maze main body 21 in real time.

In one embodiment, sensor 22 may be a plurality of pressure sensors; the pressure sensor detects whether the current pressure data changes, and when the pressure sensor detects that the current pressure data changes, the position of a target to be detected at the current pressure sensor is determined; and when the pressure sensor does not detect that the current pressure data of the pressure sensor changes, determining that the target to be measured is not located at the current position of the pressure sensor.

In another embodiment, the sensor 22 may also be a plurality of temperature sensors, the temperature sensors detect whether the temperature data of the temperature sensors changes, and when the temperature sensors detect that the temperature data of the temperature sensors changes, it is determined that the target to be measured is located at the position of the current temperature sensor; and when the temperature sensor does not detect that the temperature data of the temperature sensor changes, determining that the target to be measured is not located at the current position of the temperature sensor.

Specifically, other specific structures and functions of the sensor 22 are the same as or similar to those of the sensor 12 according to the above embodiment, and the same or similar technical effects can be achieved.

The controller 25 is connected to the sensor 22, and is configured to acquire a position sensing signal sensed by the sensor 22, so as to determine a position or a motion trajectory of the object to be measured based on the position sensing signal. In one embodiment, the controller 25 may be a single chip with bluetooth wireless transmission function. Specifically, the specific structure and function of the controller 25 are the same as or similar to those of the controller 13 according to the above embodiment, and the same or similar technical effects can be achieved.

The analog-to-digital converter 23 is connected to the sensor 22 and the controller 25, and is configured to receive and convert the position sensing signal detected by the sensor 22, and send the converted position sensing signal to the controller 25. Specifically, when the sensor 22 is a pressure sensor, the analog-to-digital converter 23 receives a signal from the output of the pressure sensor, and converts an input voltage signal into an output digital signal to facilitate data processing by the controller 25.

The communication circuit 24 is connected with the controller 25, and is used for transmitting the position or the motion track of the target to be detected to the display for displaying; the communication circuit 24 may specifically include any one of a bluetooth communication circuit, a Wi-Fi communication circuit, a short-range wireless communication circuit, an ultra-wideband communication circuit, and a zigbee network communication circuit; the display may be a computer and/or a cell phone.

In the embodiment, after the controller 25 receives the data from the analog-to-digital converter 23, stores the data and simply processes the data, the data is transmitted to the display through the communication circuit 24, so as to share the data and observe the motion position of the object to be measured in real time.

In the plus maze device 20 provided by the embodiment, the plus maze main body 21 is arranged, so that the target to be measured can move on the plus maze main body 21, and an anxiety and depression research experiment is performed; meanwhile, a sensor 22 is arranged on the cross maze main body 21 to sense a position sensing signal of the target to be measured on the cross maze main body 21 in real time; in addition, by arranging the analog-to-digital converter 23, the analog-to-digital converter 23 is respectively connected with the sensor 22 and the controller 25 so as to convert the received position sensing signal, so that the controller 25 can conveniently process the converted data at a later stage; in addition, the controller 25 is arranged and connected with the sensor 22 to obtain a position sensing signal sensed by the sensor 22 and determine the position or motion track of the object to be measured on the plus maze main body 21 based on the position sensing signal; finally, the communication circuit 24 is connected with the controller 25 by arranging the communication circuit 24 so as to transmit the motion trail of the target to be detected to the display for displaying; compared with the prior art that the obtained video is analyzed after the experiment is finished to obtain the position information of the target to be tested, the device 20 can not only carry out anxiety and depression research experiment, but also obtain the position information of the target to be tested in real time in the experiment process, and simultaneously can check and solve the problems encountered in the experiment process in real time; in addition, a video does not need to be shot by using a camera, and the step of analyzing the video after the experiment is omitted, so that the experiment time can be saved, and the accuracy of the data can be improved.

The above embodiments are merely examples and are not intended to limit the scope of the present disclosure, and all modifications, equivalents, and flow charts using the contents of the specification and drawings of the present disclosure or those directly or indirectly applied to other related technical fields are intended to be included in the scope of the present disclosure.

Claims

1. A plus labyrinth device, comprising:

a cross maze main body;

the sensor is arranged on the cross maze main body and used for sensing a position sensing signal of a target to be measured on the cross maze main body in real time;

and the controller is connected with the sensor and is used for acquiring the position sensing signal so as to determine the position or the motion track of the target to be detected based on the position sensing signal.

2. The plus labyrinth device according to claim 1, wherein the sensor is laid on the upper surface of the plus labyrinth body, and is configured to detect whether there is a position of the object to be detected on the sensor currently according to a change of its data, so as to sense a position sensing signal of the object to be detected on the plus labyrinth body in real time.

3. The plus labyrinth device according to claim 2, wherein the sensor is a plurality of pressure sensors which are laid on the upper surface of the plus labyrinth body at intervals and arranged at the edge of the plus labyrinth body; the pressure sensor detects whether the current pressure data of the pressure sensor changes or not, and when the pressure data of the pressure sensor changes, the target to be detected is located at the current position of the pressure sensor.

4. The plus labyrinth device according to claim 3, characterized in that the pressure sensor comprises a semiconductor pressure sensor;

the cross maze main part is including opening the arm and closing the arm, open the arm and/or close the arm and constitute by a plurality of independent setting's platelet, and every all be provided with one on the platelet pressure sensor.

5. The plus labyrinth device according to claim 2, wherein the sensor is a plurality of temperature sensors which are arranged at intervals on the upper surface of the plus labyrinth body and at the edge of the plus labyrinth body; the temperature sensor detects whether the current temperature data of the temperature sensor changes or not, and determines that the target to be detected is located at the current position of the temperature sensor when the temperature data of the temperature sensor changes.

6. The plus labyrinth device according to claim 1, further comprising an analog-to-digital converter, wherein the analog-to-digital converter is respectively connected to the sensor and the controller, and is configured to receive and convert the position sensing signal detected by the sensor, and send the converted position sensing signal to the controller.

7. The plus maze device of any one of claims 1-6 further comprising a communication circuit connected to the controller for transmitting the position or motion trajectory of the object to be measured to a display for display.

8. The maze device of claim 7 wherein the communication circuit comprises any one of a bluetooth communication circuit, a Wi-Fi communication circuit, a short-range wireless communication circuit, an ultra-wideband communication circuit, a zifeng network communication circuit.

9. The plus maze device of claim 6 wherein the display is a computer and/or a cell phone.

10. The maze device of any one of claims 1-6 wherein the controller is a single chip with Bluetooth wireless transmission function.