CN111808428A - Self-healing type ultrasonic transmission bionic material - Google Patents
Self-healing type ultrasonic transmission bionic material Download PDFInfo
- Publication number
- CN111808428A CN111808428A CN202010655371.9A CN202010655371A CN111808428A CN 111808428 A CN111808428 A CN 111808428A CN 202010655371 A CN202010655371 A CN 202010655371A CN 111808428 A CN111808428 A CN 111808428A
- Authority
- CN
- China
- Prior art keywords
- parts
- self
- phase
- filler
- ultrasonic transmission
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims abstract description 40
- 239000011664 nicotinic acid Substances 0.000 title claims abstract description 20
- 230000005540 biological transmission Effects 0.000 title claims abstract description 18
- -1 polysiloxane Polymers 0.000 claims description 18
- 239000000945 filler Substances 0.000 claims description 17
- 229920001296 polysiloxane Polymers 0.000 claims description 15
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 15
- 229920002554 vinyl polymer Polymers 0.000 claims description 12
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 11
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 6
- 239000003054 catalyst Substances 0.000 claims description 6
- 238000013329 compounding Methods 0.000 claims description 6
- FLKPEMZONWLCSK-UHFFFAOYSA-N diethyl phthalate Chemical compound CCOC(=O)C1=CC=CC=C1C(=O)OCC FLKPEMZONWLCSK-UHFFFAOYSA-N 0.000 claims description 6
- 229920001971 elastomer Polymers 0.000 claims description 6
- 239000000806 elastomer Substances 0.000 claims description 6
- 229910052739 hydrogen Inorganic materials 0.000 claims description 6
- 239000001257 hydrogen Substances 0.000 claims description 6
- QYLFHLNFIHBCPR-UHFFFAOYSA-N 1-ethynylcyclohexan-1-ol Chemical compound C#CC1(O)CCCCC1 QYLFHLNFIHBCPR-UHFFFAOYSA-N 0.000 claims description 3
- 229920002873 Polyethylenimine Polymers 0.000 claims description 3
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims description 3
- 239000003112 inhibitor Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000002105 nanoparticle Substances 0.000 claims description 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 3
- KAKZBPTYRLMSJV-UHFFFAOYSA-N vinyl-ethylene Natural products C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 claims description 3
- 239000002977 biomimetic material Substances 0.000 claims 1
- 238000012549 training Methods 0.000 abstract description 14
- 229920002379 silicone rubber Polymers 0.000 abstract description 10
- 230000035699 permeability Effects 0.000 abstract description 5
- 238000003745 diagnosis Methods 0.000 abstract description 2
- 210000004872 soft tissue Anatomy 0.000 abstract description 2
- 210000000577 adipose tissue Anatomy 0.000 abstract 1
- 238000007385 chemical modification Methods 0.000 abstract 1
- 238000004088 simulation Methods 0.000 description 13
- 238000010521 absorption reaction Methods 0.000 description 4
- 238000011161 development Methods 0.000 description 3
- 239000002262 Schiff base Substances 0.000 description 2
- 150000004753 Schiff bases Chemical class 0.000 description 2
- 125000003172 aldehyde group Chemical group 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 206010011732 Cyst Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010046798 Uterine leiomyoma Diseases 0.000 description 1
- 208000035868 Vascular inflammations Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 201000011531 vascular cancer Diseases 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- 206010055031 vascular neoplasm Diseases 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
- C08L83/04—Polysiloxanes
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group
- C08L2205/025—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group containing two or more polymers of the same hierarchy C08L, and differing only in parameters such as density, comonomer content, molecular weight, structure
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
- C08L2205/035—Polymer mixtures characterised by other features containing three or more polymers in a blend containing four or more polymers in a blend
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/05—Polymer mixtures characterised by other features containing polymer components which can react with one another
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Mathematical Analysis (AREA)
- Pure & Applied Mathematics (AREA)
- Computational Mathematics (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Mathematical Optimization (AREA)
- Mathematical Physics (AREA)
- Algebra (AREA)
- Business, Economics & Management (AREA)
- Educational Administration (AREA)
- Educational Technology (AREA)
- Theoretical Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to a self-healing type ultrasonic transmission bionic material, which consists of a phase A and a phase B, and is a self-healing type ultrasonic transmission bionic silicon rubber base material which is obtained by taking two-component addition type room temperature vulcanized silicon rubber as a base body and performing chemical modification. The material can perfectly simulate human soft tissues in the aspects of touch and flexibility; meanwhile, after suturing or cutting, the suture can heal automatically after a period of time. More importantly, the material has good medical ultrasonic permeability and can be used for simulating the soft adipose tissues in an ultrasonic diagnosis and ultrasonic intervention training model.
Description
Technical Field
The invention relates to a self-healing type ultrasonic transmission bionic material, in particular to a bionic material which can be applied to a medical teaching or operation model.
Background
The medical simulation training has extremely important significance for training professional clinicians and nurses. With the gradual development of medical technology and the continuous expansion of the requirements of professional medical talents, the medical simulation training still has the defects of small development scale, most of the medical simulation training is concentrated in large cities, few types of simulation training devices and the like. The scarce teaching resources greatly influence the cultivation of professional clinical talents. The education model of the simulated medicine is rapidly developing as a brand new education method and is popularized in the international range.
Medical simulation teaching improves doctor's clinical skill and cultivates, and good medical teaching model can be directly perceived, and human tissue structure is simulated in effectual show, thereby the operation that lasts repeatedly also can effectively promote cultivateing personnel's proficiency and the degree of accuracy thereby reaches the purpose of practice training. The teaching model has different characteristics by changing materials, and the clinical skills of doctors in different fields can be more pertinently cultivated and improved.
At present, the domestic medical teaching model still has a certain gap with foreign countries. Some teaching simulation materials have many disadvantages: 1. the material is too hard and has different texture with human muscle. 2. The simulation is poor, and the operation simulation can not be carried out. 3. Can not be used for a plurality of times of training. 4. The maintenance cost is higher
The patent relates to a bionic material applicable to a medical teaching model and a preparation method thereof, and the bionic material has good self-healing property and ultrasonic permeability. Effectively makes up the defects of partial medical teaching models at present, ensures that the models have flexibility and is convenient for simulating actual operation. Good self-healing property can make the shape and performance of the model close to or reach the previous state after the model is cut. The service life of the medical teaching model is prolonged, the safety of simulation operation is improved, and the maintenance cost of the model is reduced. The research on the self-healing material has been well developed, and the self-healing material also has good application in the aspect of biological application. Meanwhile, the biological compatibility and the functions are good, and the method plays an important role in simulation teaching. In addition, the material is also ultrasonically transparent. In the medical simulation training, the material with ultrasonic permeability can be better combined with the ultrasonic technology to help the training personnel to monitor and detect the structure in real time so as to carry out the simulation training of corresponding practical operation. The material is particularly suitable for the culture of talents in surgical operations by utilizing simulation training, and the trauma caused by the traditional surgical operations can be avoided by combining ultrasonic guidance with a minimally invasive technology. At present, the domestic ultrasonic intervention treatment has also achieved achievements, and particularly has a rapid development on the treatment of benign tumors such as hysteromyoma and chocolate cyst, so that the material with the characteristics can play a good role in the clinical skill training of doctors. The medical teaching model of the ultrasonic permeable material is suitable for the diagnosis and detection operation training of vascular diseases, inflammations and tumors of head and neck, chest, abdomen, joints, soft tissues and other parts.
Disclosure of Invention
In order to solve the problem, the embodiment of the invention provides a self-healing type ultrasonic transmission bionic material. The technical scheme is as follows:
the embodiment of the invention provides a self-healing type ultrasonic transmission bionic material, which consists of a phase A and a phase B and comprises the following components:
the phase A is as follows:
50 parts of vinyl polysiloxane, wherein the vinyl content is 8-12%;
10-20 parts of a filler, wherein the filler is formed by compounding nano silicon dioxide powder and silicate powder in a mass ratio of 1: 0.2-0.5;
0.1-1 part of dye;
1-5 parts of hydrogen-containing polysiloxane, wherein the hydrogen content is 1.0-1.5%;
0.1-2 parts of inhibitor, vinyl ring body or ethynyl cyclohexanol;
3-10 parts of amino polysiloxane;
the phase B is as follows:
50 parts of vinyl polysiloxane, wherein the vinyl content is 8-12%
10-20 parts of a filler, wherein the filler is formed by compounding nano silicon dioxide powder and silicate powder in a mass ratio of 1: 0.2-0.5;
0.1-1 part of catalyst, wherein the catalyst is any one of chloroplatinic divinyl tetramethyl siloxane and chloroplatinic diethyl phthalate;
3-10 parts of aldehyde polysiloxane;
when the elastomer is used, the components are uniformly mixed at room temperature according to the mass fraction of 1: 1-2, and the mixture is poured into a mold for 6-24 hours and then cured to obtain the elastomer.
In a preferred embodiment, the silicate in the filler of phase a is encapsulated by polyethyleneimine to form nanoparticles.
Compared with the prior art, the self-healing type ultrasonic transmission bionic material provided by the invention has the following advantages: 1. self-healing: the self-healing bionic silicon rubber material is colloidal solid; cutting a notch with the length of 3-5cm and the depth of 1-3cm on the material by using a blade, and after the material is placed at room temperature for 24 hours, gradually reducing the notch until the notch disappears; after being placed at 60 ℃ for 12 h, the gap disappears, and the material is healed. The aldehyde group and the amino group have Schiff base reaction and can be healed by self after being damaged; 2. ultrasonic transmission: the phenomenon of silicon rubber that reduces sound energy during sound wave propagation by absorbing and converting the sound energy into another form of energy is called absorption attenuation. The absorption attenuation is related to the microstructure of the medium. In the patent, the nano silicon dioxide powder and silicate powder compound system of the filler can keep good permeability of ultrasonic waves, and the sound attenuation is less than or equal to 0.05 dB/(cm.M Hz); 3. performance: the self-healing bionic silicon rubber material has good thermodynamic stability, the decomposition temperature is more than 450 ℃, the hardness (Shore A) is 30-40, and the tensile strength is as follows: 0.3-5MPa, elongation at break of 80-130%, and the self-healing bionic silicon rubber material has good sound transmission characteristic, sound characteristic impedance of (1.5 x 106-1.7 x 106) Pa.s/m, sound attenuation of less than or equal to 0.05 dB/(cm.M Hz), and is a good medical ultrasonic transmission material.
Detailed Description
The embodiment of the invention provides a self-healing type ultrasonic transmission bionic material, which consists of a phase A and a phase B and comprises the following components:
the phase A is as follows:
50 parts of vinyl polysiloxane, wherein the vinyl content is 8-12%;
10-20 parts of a filler, wherein the filler is formed by compounding nano silicon dioxide powder and silicate powder in a mass ratio of 1: 0.2-0.5;
0.1-1 part of dye;
1-5 parts of hydrogen-containing polysiloxane, wherein the hydrogen content is 1.0-1.5%;
0.1-2 parts of inhibitor, vinyl ring body or ethynyl cyclohexanol;
3-10 parts of amino polysiloxane;
the phase B is as follows:
50 parts of vinyl polysiloxane, wherein the vinyl content is 8-12%
10-20 parts of a filler, wherein the filler is formed by compounding nano silicon dioxide powder and silicate powder in a mass ratio of 1: 0.2-0.5;
0.1-1 part of catalyst, wherein the catalyst is any one of chloroplatinic divinyl tetramethyl siloxane and chloroplatinic diethyl phthalate;
3-10 parts of aldehyde polysiloxane;
when the elastomer is used, the components are uniformly mixed at room temperature according to the mass fraction of 1: 1-2, and the mixture is poured into a mold for 6-24 hours and then cured to obtain the elastomer.
In a preferred embodiment, the silicate in the filler of phase a is encapsulated by polyethyleneimine to form nanoparticles.
Compared with the prior art, the self-healing type ultrasonic transmission bionic material provided by the invention has the following advantages: 1. self-healing: the self-healing bionic silicon rubber material is colloidal solid; cutting a notch with the length of 3-5cm and the depth of 1-3cm on the material by using a blade, and after the material is placed at room temperature for 24 hours, gradually reducing the notch until the notch disappears; after being placed at 60 ℃ for 12 h, the gap disappears, and the material is healed. The aldehyde group and the amino group have Schiff base reaction and can be healed by self after being damaged; 2. ultrasonic transmission: the phenomenon of silicon rubber that reduces sound energy during sound wave propagation by absorbing and converting the sound energy into another form of energy is called absorption attenuation. The absorption attenuation is related to the microstructure of the medium. In the patent, the nano silicon dioxide powder and silicate powder compound system of the filler can keep good permeability of ultrasonic waves, and the sound attenuation is less than or equal to 0.05 dB/(cm.M Hz); 3. performance: the self-healing bionic silicon rubber material has good thermodynamic stability, the decomposition temperature is more than 450 ℃, the hardness (Shore A) is 30-40, and the tensile strength is as follows: 0.3-5MPa, elongation at break of 80-130%, and the self-healing bionic silicon rubber material has good sound transmission characteristic, sound characteristic impedance of (1.5 x 106-1.7 x 106) Pa.s/m, sound attenuation of less than or equal to 0.05 dB/(cm.M Hz), and is a good medical ultrasonic transmission material.
Claims (2)
1. A self-healing type ultrasonic transmission bionic material consists of a phase A and a phase B, and comprises the following components:
the phase A is as follows:
50 parts of vinyl polysiloxane, wherein the vinyl content is 8-12%;
10-20 parts of a filler, wherein the filler is formed by compounding nano silicon dioxide powder and silicate powder in a mass ratio of 1: 0.2-0.5;
0.1-1 part of dye;
1-5 parts of hydrogen-containing polysiloxane, wherein the hydrogen content is 1.0-1.5%;
0.1-2 parts of inhibitor, vinyl ring body or ethynyl cyclohexanol;
3-10 parts of amino polysiloxane;
the phase B is as follows:
50 parts of vinyl polysiloxane, wherein the vinyl content is 8-12%
10-20 parts of a filler, wherein the filler is formed by compounding nano silicon dioxide powder and silicate powder in a mass ratio of 1: 0.2-0.5;
0.1-1 part of catalyst, wherein the catalyst is any one of chloroplatinic divinyl tetramethyl siloxane and chloroplatinic diethyl phthalate;
3-10 parts of aldehyde polysiloxane;
when the elastomer is used, the components are uniformly mixed at room temperature according to the mass fraction of 1: 1-2, and the mixture is poured into a mold for 6-24 hours and then cured to obtain the elastomer.
2. A self-healing type ultrasonic transmission biomimetic material according to claim 1, characterized in that: and the silicate in the filler of the phase A is wrapped by polyethyleneimine to form nanoparticles.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010655371.9A CN111808428A (en) | 2020-07-09 | 2020-07-09 | Self-healing type ultrasonic transmission bionic material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010655371.9A CN111808428A (en) | 2020-07-09 | 2020-07-09 | Self-healing type ultrasonic transmission bionic material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111808428A true CN111808428A (en) | 2020-10-23 |
Family
ID=72842050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010655371.9A Pending CN111808428A (en) | 2020-07-09 | 2020-07-09 | Self-healing type ultrasonic transmission bionic material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111808428A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112521754A (en) * | 2020-10-30 | 2021-03-19 | 广东工业大学 | MXene nanosheet compounded heat-conducting gel with thermal self-repairing performance and preparation method thereof |
| CN113313988A (en) * | 2021-05-26 | 2021-08-27 | 中南大学湘雅二医院 | Reusable and automatic-repairing surgical simulation equipment |
-
2020
- 2020-07-09 CN CN202010655371.9A patent/CN111808428A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112521754A (en) * | 2020-10-30 | 2021-03-19 | 广东工业大学 | MXene nanosheet compounded heat-conducting gel with thermal self-repairing performance and preparation method thereof |
| CN113313988A (en) * | 2021-05-26 | 2021-08-27 | 中南大学湘雅二医院 | Reusable and automatic-repairing surgical simulation equipment |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103886797B (en) | A kind of height emulation laparoscopic surgery simulation trainer | |
| US10847057B2 (en) | Synthetic tissue structures for electrosurgical training and simulation | |
| US10713973B2 (en) | Model of viscera, tissues, or organs | |
| CA2774995C (en) | Surgical training aids and methods of fabrication thereof | |
| CN111808428A (en) | Self-healing type ultrasonic transmission bionic material | |
| JP2010029650A (en) | Medical ultrasonic phantom | |
| Baba et al. | Development of a tailored thyroid gland phantom for fine-needle aspiration cytology by three-dimensional printing | |
| Martinek et al. | Training on an ex vivo animal model improves endoscopic skills: a randomized, single-blind study | |
| CN109620327A (en) | Button Skin stretching device and skin drawing and stretching method | |
| CN209895642U (en) | Human body model for renal biopsy teaching and operation training | |
| CN204706272U (en) | A kind of Urology Surgery lower urinary tract Minimally Invasive Surgery training pattern | |
| Yang et al. | Laparoscopic urethrovesical anastomosis: a model to assess surgical competency | |
| CN109859600A (en) | Ultrasound guidance breast tumor puncturing pattern and preparation method thereof | |
| CN109251452A (en) | Gel composite material and preparation method and forming technology for oral cavity training model | |
| CN208796547U (en) | Disposable emulating organization ultrasonic body mould | |
| CN114854049A (en) | Soft tissue-like elastic hydrogel and preparation method and application of hydrogel tissue organ model thereof | |
| CN112071178A (en) | Method for establishing operation model by using animal organ | |
| WO2020171116A1 (en) | Artificial organ model, method for producing same, and method for training surgical techniques using artificial organ model | |
| CN112071175A (en) | Oviduct windowing embryo-taking model for medical training and manufacturing method thereof | |
| Jiang et al. | A training model for laparoscopic urethrovesical anastomosis | |
| US11056021B2 (en) | Method for producing simulated animal organ and simulated animal organ | |
| CN215814734U (en) | Training model for treatment under endoscopic fundal varicose vein | |
| CN220065010U (en) | Pancreas intestine anastomosis reconstruction training model | |
| CN118126417A (en) | Tissue-simulated puncture body mold material, preparation method thereof and tissue-simulated puncture body mold | |
| CN216211830U (en) | Neck puncture biopsy model |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20201023 |