CN111773498A - Medicine adding implementation method and device applied to lung disease treatment - Google Patents

Medicine adding implementation method and device applied to lung disease treatment Download PDF

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Publication number
CN111773498A
CN111773498A CN202010504413.9A CN202010504413A CN111773498A CN 111773498 A CN111773498 A CN 111773498A CN 202010504413 A CN202010504413 A CN 202010504413A CN 111773498 A CN111773498 A CN 111773498A
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Prior art keywords
dosing
medicine
drug
inlet
added
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Chinese (zh)
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齐发云
王晓明
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Jiujiu Medical Technology Shenzhen Co ltd
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Jiujiu Medical Technology Shenzhen Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/1005Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16Devices to humidify the respiration air
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring

Abstract

The invention discloses a medicine adding realization method and a medicine adding realization device applied to lung disease treatment, wherein the method comprises the following steps: the drug adding control device receives input data, generates drug adding control parameters according to the received data, and generates drug adding parameters according to the drug adding control parameters, wherein the drug adding parameters are used for controlling the drug adding device to add required drugs into the device to be added, the device to be added is a respirator or spray treatment equipment, and the drug adding parameters comprise one or more combinations of the drug type, the drug adding amount, the drug adding speed, the drug adding time period, the drug adding frequency and the drug adding change condition of the required drugs. Therefore, the intelligent control of dosing can be realized in the aerosol therapy, the treatment scheme of the lung diseases can be further optimized, and the improvement of the treatment effect of the aerosol therapy on the lung diseases is facilitated.

Description

Medicine adding implementation method and device applied to lung disease treatment
Technical Field
The invention relates to the technical field of intelligent control, in particular to a medicine adding implementation method and device applied to lung disease treatment.
Background
The lung is one of the most important organs of the body and is also the most vulnerable tissue of the body. Pulmonary diseases are the most common human diseases and include infectious pulmonary diseases, pulmonary diseases associated with atmospheric pollution and smoking, pulmonary tumors, occupational pulmonary diseases, immunological pulmonary diseases, unexplained pulmonary diseases, and the like. The treatment methods of lung diseases mainly include drug therapy, surgical therapy, radiotherapy and chemotherapy, gene therapy, interventional therapy, and the like, wherein inhalation therapy among drug therapy is widely used, and mainly includes aerosol inhalation therapy, aerosol infusion therapy through a mist storage tank, dry powder infusion therapy, aerosol therapy, and the like.
The aerosol inhalation therapy is characterized in that a special aerosol generating device is used for forming aerosol liquid droplets or solid particles from water and liquid medicine, and the aerosol liquid droplets or the solid particles are inhaled and deposited in respiratory tracts, alveoli and target organs to achieve the purposes of treating diseases and improving symptoms. The traditional Chinese medicine composition has the advantages of capability of enabling the medicine to directly reach an airway or a lung, small dosage, quick response time of the medicine and the like, and has the characteristic of relatively low side effect compared with the whole body and mind medicine treatment. The traditional atomization therapy is a treatment method implemented by the way that a doctor determines the type and the quantity of medicine according to the diagnosis result of lung diseases of a patient and then adopts an atomization technology. The method is relatively simple for the treatment of common upper respiratory lung diseases and the treatment of common pneumonia, but is more dependent on the experience of medical staff, has poor response and adaptability to the treatment of lung diseases of patients and the conditions of further development, particularly in the treatment of pneumonia caused by virus infection, the conditions of different stages, lungs and other organs and even the whole body of the patients in the development of the disease stage are changed, the condition change is rapid, if the real-time adjustment of the medication parameters of the medicines for inhalation treatment is not performed, the expected treatment purpose cannot be achieved by light persons, and even the lives of the patients are endangered by serious persons. Therefore, how to realize intelligent control of dosing is very important.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a dosing implementation method and device applied to lung disease treatment, which can implement intelligent control of dosing in the aerosol therapy and further is beneficial to improving the treatment effect of the aerosol therapy on lung diseases.
In order to solve the technical problem, the present invention discloses, in a first aspect, a drug administration implementation method for pulmonary disease treatment, the method being applied to a drug administration implementation system, the drug administration implementation system at least including a drug administration control device, the method including:
the drug adding control device receives input data;
the drug adding control device generates drug adding control parameters according to the received data, and generates drug adding parameters according to the drug adding control parameters, the drug adding parameters are used for controlling the drug adding device to add required drugs into the device to be added, and the device to be added is a respirator or spray treatment equipment;
the medicine adding parameters comprise one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
As an optional implementation manner, in the first aspect of the embodiments of the present invention, the data includes one or more of real-time status data of a patient, working status data of the device to be medicated, real-time status data of atomization, medicated drug type and particle parameters, and inhalation port parameter data of the device to be medicated.
As an alternative implementation, in the first aspect of this embodiment of the present invention, the medicated implementation system further comprises the medicated device and/or the device to be medicated,
and, the method further comprises:
the medicine adding device receives the medicine adding parameters generated by the medicine adding control device and adds the required medicine into the device to be added according to the medicine adding parameters.
As an alternative implementation, in the first aspect of this embodiment of the invention, the medicated device comprises at least two medicated branches.
As an optional implementation manner, in the first aspect of the embodiment of the present invention, each of the dosing branches includes a dosing inlet, a dosing real-time adjustment proportional solenoid valve corresponding to the dosing inlet, and a dosing outlet corresponding to the dosing inlet, and the dosing real-time adjustment proportional solenoid valve included in each of the dosing branches is used for being connected to a solenoid valve controller;
one end of the dosing inlet of each dosing branch is connected with a dosing inlet of a dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet, a dosing outlet of the dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet is connected with one end of a dosing outlet corresponding to the dosing inlet, and the other end of the dosing outlet corresponding to the dosing inlet is used for being connected with a dosing inlet of an air pipe/air suction pipe of the device to be dosed;
the other end of the drug feeding inlet of each drug feeding branch is connected with a special drug storage system of a hospital, and the special drug storage system is provided with a drug feeding power device which can be linked with the drug feeding control device.
As an optional implementation manner, in the first aspect of the embodiment of the present invention, the drug administration control device includes a drug administration controller and a data input interface corresponding to the data; the dosing controller is connected with the electromagnetic valve controller;
wherein, add medicine controlling means according to the data generation that receive add medicine control parameter, include:
the dosing controller generates dosing control parameters for the solenoid valve controller to adjust dosing real-time adjusting proportional solenoid valves included in each dosing branch through real-time processing of the received data based on a medical expert system, a big data processing algorithm, a dosing scheme self-learning algorithm and a decision optimization algorithm.
As an alternative implementation, in the first aspect of the embodiment of the present invention, the drug adding device includes the solenoid valve controller, or the drug adding control device includes the solenoid valve controller;
when the medicine adding device comprises the electromagnetic valve controller, the medicine adding device adds the required medicine into the device to be added according to the medicine adding parameters, and the medicine adding device comprises:
the electromagnetic valve controller determines at least one target medicine adding branch corresponding to the medicine to be added according to the medicine adding parameters, adjusts the medicine adding real-time adjusting proportion electromagnetic valve included in each target medicine adding branch according to the medicine adding parameters, and adds the required medicine to the air feed pipe/air suction pipe of the medicine adding device through the medicine adding real-time adjusting proportion electromagnetic valve included in each target medicine adding branch.
As an optional implementation manner, in the first aspect of the embodiment of the present invention, when the device to be medicated is the ventilator, a device matching with the medicated is disposed on the ventilator, and the device matching with the medicated includes an air inlet branch, an air outlet branch, and a patient breathing port connected to the air inlet branch and the air outlet branch;
the air inlet branch comprises an oxygen inlet, an air-oxygen mixing part, an air inlet pipe, a humidifying and atomizing part and an air inlet connected with the breathing port of the patient, the air-oxygen mixing part is connected with the oxygen inlet and the air inlet, the air inlet pipe is provided with an oxygen detection device or a port used for connecting the oxygen detection device, a safety valve, a first pressure detection device or a port used for connecting the first pressure detection device, and a port connected with the dosing device, the port connected with the dosing device is positioned behind the first pressure detection device or the port used for connecting the first pressure detection device and in front of the humidifying and atomizing part, and the respirator is connected with the dosing device through the port connected with the dosing device;
the air outlet branch comprises an air outlet pipe, and a second pressure detection device or a connector, an expiratory valve and a flow detection device which are used for connecting the second pressure detection device or a connector and an air outlet which are used for connecting the flow detection device are arranged on the air outlet pipe.
As an alternative implementation manner, in the first aspect of this embodiment of the present invention, the drug adding device includes all the drug adding branches connected to the drug to be added device in series, or connected to the drug to be added device in parallel, or connected to the drug to be added device in series and parallel.
As an alternative implementation manner, in the first aspect of the embodiments of the present invention, the drug adding branch is specifically connected to the device to be added in parallel by providing drug adding ports with the same structure on the same horizontal cross section of the air/air suction pipe of the device to be added or on the cylindrical spiral distribution surface of the air/air suction pipe of the device to be added, and the drug adding ports and the interfaces of the air/air suction pipe of the device to be added have an inclination angle.
The invention discloses a dosing control device, which is applied to a dosing implementation system and comprises a data input interface and a dosing controller; the dosing controller is connected with the dosing device; wherein:
the data input interface is used for receiving input data;
the dosing controller is used for generating dosing control parameters according to the received data and generating medicine adding parameters according to the dosing control parameters, the medicine adding parameters are used for controlling a dosing device to add required medicines into a device to be dosed, and the device to be dosed is a respirator or spray treatment equipment;
the medicine adding parameters comprise one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
The third aspect of the embodiment of the invention discloses a dosing device, which is connected with a dosing control device and comprises at least two dosing branches, wherein:
the drug adding device is used for receiving the drug adding parameters generated by the drug adding control device and adding the required drug into the device to be added according to the drug adding parameters; the device to be added with the medicine is a respirator or a spray therapy, the medicine adding parameters are generated by the medicine adding control device according to received data, and the medicine adding parameters comprise one or more combinations of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding speed of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
As an alternative embodiment, in the third aspect of the invention, the medicated device comprises at least two medicated branches.
As an optional implementation manner, in the third aspect of the present invention, each of the dosing branches includes a dosing inlet, a dosing real-time adjustment proportional solenoid valve corresponding to the dosing inlet, and a dosing outlet corresponding to the dosing inlet, the dosing real-time adjustment proportional solenoid valve included in each of the dosing branches is used for being connected to a solenoid valve controller, and the solenoid valve controller is used for being connected to the dosing control device;
one end of the dosing inlet of each dosing branch is connected with a dosing inlet of a dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet, a dosing outlet of the dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet is connected with one end of a dosing outlet corresponding to the dosing inlet, and the other end of the dosing outlet corresponding to the dosing inlet is used for being connected with a dosing inlet of an air pipe/air suction pipe of the device to be dosed;
the other end of the drug feeding inlet of each drug feeding branch is connected with a special drug storage system of a hospital, and the special drug storage system is provided with a drug feeding power device which can be linked with the drug feeding control device.
Compared with the prior art, the embodiment of the invention has the following beneficial effects:
in the embodiment of the invention, the dosing control device receives input data, generates dosing control parameters according to the received data, and generates medicine adding parameters according to the dosing control parameters, wherein the medicine adding parameters are used for controlling the dosing device to add required medicines into a device to be dosed, and the device to be dosed is a respirator or spray therapy equipment; the medicine adding parameters comprise one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition. Therefore, the intelligent control of dosing can be realized in the aerosol therapy according to the received data, so that the treatment scheme of the lung diseases can be optimized, and the treatment effect of the aerosol therapy on the lung diseases can be improved.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a dosing implementation system disclosed in an embodiment of the present invention;
FIG. 2 is a schematic flow chart of a drug administration implementation method for treating pulmonary diseases according to an embodiment of the present invention;
FIG. 3 is a schematic flow chart of another embodiment of a dosing implementation method for pulmonary disease treatment;
FIG. 4 is a schematic structural diagram of a dosing control device disclosed in the embodiments of the present invention;
FIG. 5 is a schematic structural diagram of a drug adding device disclosed in the embodiments of the present invention;
fig. 6 is a schematic structural diagram of a device matched with medicine feeding and arranged on a respirator, which is disclosed by the embodiment of the invention.
Detailed Description
In order to make the technical solutions of the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The terms "first," "second," and the like in the description and claims of the present invention and in the above-described drawings are used for distinguishing between different objects and not for describing a particular order. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, apparatus, article, or article that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or article.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the invention. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
The invention discloses a medicine adding realization method and a medicine adding realization device applied to lung disease treatment, which can realize intelligent control of medicine adding in an atomization therapy according to received data, further optimize a treatment scheme of lung diseases, be beneficial to improving the treatment effect of the atomization therapy on the lung diseases, realize intelligent control of medicine adding in multiple ways while realizing intelligent control of medicine adding, and further realize diversified medicine adding modes; in addition, the received data are various, so that the matching degree of the generated medicine adding parameters and the lung diseases of the patient can be improved when medicine adding control is realized, and further the treatment effect of the lung diseases can be further improved; in addition, the dosing control can be realized based on the electromagnetic valve controller and the dosing real-time adjusting proportional electromagnetic valve, and the dosing efficiency and the dosing control accuracy are favorably improved; in addition, the dosing device adopts a modular design, a plurality of single modules can realize dosing in a serial, parallel or serial and parallel combined mode, a diversified dosing realization mode is provided, and the multi-stage serial connection of the single modules can realize multi-stage multiplication of a dosing port, thereby being beneficial to realizing an optimized treatment scheme of mixed dosing; in addition, when the medicine adding device is applied to a respirator, the medicine adding device is connected in front of the humidifying and atomizing part of the air inlet pipe/the air suction pipe, so that the function of the respirator can be improved, namely, the function of only providing breathing is upgraded into the function of medicine treatment. The following are detailed below.
In order to better understand the dosing implementation method and device applied to the treatment of the pulmonary disease, a dosing implementation system applied to the dosing implementation method applied to the treatment of the pulmonary disease is described first. As shown in fig. 1, the medicine-adding implementation system applied in the medicine-adding implementation method for treating pulmonary diseases disclosed by the present invention may at least include a medicine-adding control device, and further, may further include a medicine-adding device and/or a device to be added, where the device to be added may be a ventilator or a spray therapy device. The dosing control device receives input data, generates dosing control parameters according to the received data, and generates medicine adding parameters according to the dosing control parameters so as to control the dosing device to add required medicines into the device to be dosed. The following are detailed below.
Example one
Referring to fig. 2, fig. 2 is a schematic flow chart of a dosing implementation method for treating pulmonary diseases according to an embodiment of the present invention. Wherein, the method described in fig. 2 is applied to a dosing implementation system, which at least comprises a dosing control device. As shown in fig. 2, the medicated implementation method applied to the treatment of pulmonary diseases may include the following operations:
101. the dosing control device receives input data.
102. The dosing control device generates dosing control parameters according to the received data, and generates medicine adding parameters according to the dosing control parameters.
The generated medicine adding parameters are used for controlling the medicine adding device to add required medicine into the device to be added, optionally, the medicine adding device comprises at least two medicine adding branches to realize multipath medicine adding, the device to be added can be a respirator or spray treatment equipment, and the embodiment of the invention is not limited by the way. Optionally, the medicine adding parameters include one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added, and the medicine adding variation condition.
In an alternative embodiment, the data may be real-time, non-real-time, or a combination thereof. Further optionally, the data may include one or more of real-time status data of the patient, working status data of the device to be medicated, real-time status data of the atomization, types and particle parameters of the medicated drug, and parameter data of the inhalation port of the device to be medicated.
In this alternative embodiment, the real-time patient status data may include one or more of basic patient information, lung examination items of the patient, medical examination data of other organs related to the lung of the patient, blood collection time of the patient, medical allergy history of the patient, latest medical allergy test data of the patient, and other medical examination data. The basic information of the patient can include one or more combinations of the age, sex, height, various physiological parameters and the like of the patient, and the lung examination items of the patient mainly include one or more combinations of bacteria (sputum culture and/or blood culture), viruses, chemiluminescence, blood coagulation, cellular immunity, biochemical items and the like. For example: the increase of the sputum is commonly seen in bronchiectasis, lung abscess, pulmonary edema, chronic bronchitis and the like, the color change of the sputum is closely related to various clinical symptoms, the decision on the type and the quantity of the medicine is significant, foreign matters in the sputum also have important clinical significance, and the treatment scheme can be influenced.
In addition, since the lung diseases are closely related to other organs, the conditions of other organs will directly influence dosing decisions, such as spleen, pulmonary lymph nodes and bone marrow, heart and cardiovascular, liver and gallbladder, kidney, brain tissue, esophagus, stomach and intestinal mucosa, etc., and medical examination data of other organs related to the lung of a patient also needs to be input into the system; the time of blood collection is closely related to the patient condition, such as: fever status, blood pressure status, coma, granulocyte and platelet counts, etc.; the patient's history of drug susceptibility and the latest experimental data of drug susceptibility will influence the decision to take medication; procalcitonin PCT (ng/ml) concentration reflects the severity of diseases and is important patient condition data, hypersensitive C-reactive protein can identify bacterial and viral infection, and troponin quantification cTn (I) is used for clinical early auxiliary diagnosis of acute myocardial infarction, unstable angina, acute myocarditis, acute coronary syndrome and the like; the B-type natriuretic titanium precursor (NT-proBNP) is used for early discovering patients with heart failure, carrying out risk stratification, monitoring treatment, judging prognosis, monitoring the curative effect of heart failure drugs, risk evaluation of acute coronary syndrome, screening and diagnosis of patients with non-cardiac heart failure, and distinguishing dyspnea caused by heart failure and other reasons; the rising of the level of the D-dimer indicates the existence of secondary hyperfibrinolysis (such as DIC), the rising of the level of the fibrin (protogen) degradation product FDP indicates the hyperfibrinolysis activity of the organism, the DD and FDP are jointly detected for eliminating pulmonary embolism (PTE), the optimal treatment opportunity of the patient is obtained, and the survival rate is improved; the cellular immunity CD3 (the absolute value represents the total number of T lymphocytes)/CD 4 (the absolute value can most directly reflect the condition of the human immune system)/CD 8 (the cell is an inhibitory T cell and has the function of immunosuppression), and the cellular immunity CD3 controls the dynamic change of immunity in the process of treating diseases, evaluates the treatment risk, the curative effect of medication and the recovery degree of organisms by detecting the immune cells; severe or critically severe new coronary pneumonia, which may cause over-immunity, is closely related to the continuous, rapid and massive production of the so-called cytokine storm cytokine; the synergistic effect of the proinflammatory cytokines and the inflammatory-inhibiting cytokines ensures that an organism maintains a normal and balanced immune function, but excessive proinflammatory cytokines can cause tissue congestion, edema and fever, and finally cause multi-organ functional failure; the new coronavirus invades the lung through angiotensin converting enzyme 2 (ACE-2), so that immune cells in the lung are over-activated, a large number of inflammatory factors are generated, and a cytokine storm is formed. A large amount of lung tissues can be killed by mistake at the same time of killing the virus, the ventilation function of the lung is seriously damaged, and finally, a patient can suffer from respiratory failure and even die due to oxygen deficiency. To block inflammatory factors, the application of a drug Tolizumab is an option, which indicates that cytokine monitoring of a new critical coronary pneumonia patient becomes a key, and a high-efficiency monitoring tool is used to realize qualitative or quantitative single-factor monitoring or multi-factor monitoring.
In addition, monitoring metrics that are clinically significant to the correct dosing decision may also include other medical examination data, such as: homocysteine (cardiovascular disease, diabetes, chronic kidney disease), serum adenosine deaminase activity (cirrhosis, cholecystitis, gallstones, pancreatic cancer, hepato-pancreatic ampulla, etc.), angiostatin amine oxidase (cirrhosis), leucyl aminopeptidase (involved in the degradation or renewal of histones and certain titanium species), β 2-MG microglobulin in serum (renal function, nephropathy, diabetes, urinary tract infection), cystatin C (diabetes, nephropathy), N-acetyl- β -D glucosaminidase (nephropathy, diabetes), serum NAG (hepatobiliary disease), etc.
In this optional embodiment, further optionally, the device to be medicated may be a ventilator, and the main machine of the ventilator is a device for providing respiratory management, which is composed of a control circuit, a mechanical motion component and a gas circuit, and is capable of supplying air and oxygen mixed gas to the patient according to a set ventilation mode and parameters, wherein the working state data of the ventilator mainly includes one or more combinations of ventilation mode selection, airway pressure, upper pressure limit setting, lower pressure limit setting, tidal volume, respiratory ratio, respiratory frequency, and the like, and the working state data of the ventilator is sent to the medicated control device. Namely: when the medicine adding realization system is applied to the respirator, all relevant parameters of the respirator are sent to a medicine adding controller which is included in the medicine adding control device and used as a part of input data of the medicine adding controller to participate in the selection of medicine adding types, the determination of medicine adding quantity, the determination of medicine adding time, the determination of medicine adding duration and other parameters.
In the alternative embodiment, the aerosol inhalation therapy is mainly aerosol inhalation therapy, which can inhale and deposit liquid droplets or solid particles formed by aerosol of moisture and liquid medicine to target organs of respiratory tract and alveolus to improve symptoms and treat diseases, and the aerosol inhalation also has a certain effect of humidifying the airway. As a further alternative, the nebulization real-time status data may include one or a combination of more of the following data:
mechanisms of aerosol deposition such as inertial impaction, gravity settling and diffusion. The deposition of aerosol particles in the lung during mechanical ventilation is generally less than 5%, the deposition of aerosol particles in the lung by a pneumatic atomizer is about 3%, and the deposition of aerosol particles in the lung by a pressure type quantitative aerosol device MDI is about 6%, but the physiological effect is still achieved. Furthermore, endotracheal intubation can affect the aerosol into the lower respiratory tract, generally requiring higher doses if the same therapeutic effect is to be achieved, but can significantly increase the amount of lung deposits if the nebulizer is connected to the ventilator tubing in a manifold and is only open during inhalation;
tidal volume, theoretically the larger the tidal volume the more conducive to the conduction and settling of aerosol particles within the airway, but the larger tidal volume may cause ventilator-related lung injury;
a ventilator mode, wherein the number of particles for aerosol therapy is much less during mechanical ventilation and spontaneous breathing, and the Controlled Mechanical Ventilation (CMV), auxiliary mechanical control (AC), and inspiratory Pressure Support (PSV) modes all produce the same deposition effect and are all significantly lower than the Continuous Positive Airway Pressure (CPAP) mode at the same tidal volume;
the air suction flow rate determines whether the air is laminar flow or vortex flow in the pipeline, aerosol in the vortex flow is easy to collide to synthesize larger liquid drops, and the gravity settling chance is increased. Meanwhile, the aerosol rotating with the airflow has more chances to impact the ventilator loop and the conduit wall due to inertia;
inhalation times, long inhalation times can increase aerosol particle deposition in the lungs;
synchronous, pneumatic atomizers are of two types: one is persistent; one is that the ventilator provides a ventilator that can be synchronized with breathing and that the effectiveness of using a synchronized nebulizer is higher than a continuous nebulizer.
In this alternative embodiment, the medicated drug categories may include combinations of one or more of the following:
the common atomized inhalation medicaments mainly comprise normal saline, hypertonic saline, bronchodilators and anticholinergics, and in addition, adrenocortical hormones, budesonide and fluticasone propionate, and also comprise: beclomethasone dipropionate, budesonide, salmeterol ticasone, budesonide formoterol and the like;
other atomized medicines mainly comprise phlegm-resolving and phlegm-eliminating agents (Musultan), antibiotics (streptomycin, kanamycin, gentamicin and chloramphenicol), antimycotic antibiotics (amphotericin nystatin), anesthesia (lidocaine) and the like. Wherein, the atomized glucocorticoid can control asthma symptoms, improve lung function, relieve airway inflammation and airway hyperresponsiveness, reduce asthma attack, reduce asthma mortality and improve life quality;
a new coronary pneumonia therapeutic agent;
the antiviral therapeutic drugs are mostly taken in capsules and are infused into veins at present, and can be clinically tested to evaluate the curative effect by aerosol inhalation, so that the problems of adverse reactions, contraindications, interaction with other drugs and the like of the drugs need to be noticed. For patients with extensive double-lung diseases and heavy patients and patients with increased IL-6 level detected in laboratories, the Tuzhuzumab can be tried for treatment, and at present, the intravenous infusion mode is mainly adopted, and the atomization inhalation evaluation curative effect can be clinically tested; for patients with progressive deterioration of oxygenation indexes, rapid progress of imaging and over-activated state of organism inflammatory reaction, glucocorticoid is used in a short time as appropriate, and the mode of taking capsules is mainly adopted at present, so that the atomization inhalation can be researched to evaluate the curative effect;
the traditional Chinese medicine for treating the new coronary pneumonia has traditional Chinese medicine prescriptions at different stages, and at present, capsules or decoction are mostly taken, and the atomization inhalation can be studied to evaluate the curative effect. The nano-particles are mainly used as carriers, drugs are placed in the nano-particles or adsorbed on the surfaces of the nano-particles, and specific ligands are combined to facilitate the combination of the cell surface specific receptors and target analysis receptors, so that the targeted therapy mode is promoted. The nano-drug carrier has special properties, and can move different drugs to specific parts of the body of a patient at corresponding time. In addition, the nano-drug carrier can also adjust the targeted drug delivery, release speed, transdermal absorption and targeted drug delivery of the drug, and effectively reduce the adverse drug reaction.
In this alternative embodiment, the inlet port parameter data of the device to be medicated may consist essentially of a combination of one or more of oxygen, temperature, humidity, flow, volume, pressure, and the like. When the medicine adding system is applied to a respirator, the medicine is added in an inspiration state by matching with the working mode and inspiration parameters of the respirator, such as: pressure Support Ventilation (PSV), Continuous Positive Airway Pressure (CPAP), bi-level positive airway pressure (BiPAP), autonomous ventilation (SPONT), Mandatory Minute Ventilation (MMV), and APRV realize a new ventilation mode of alveolar ventilation, pressure modulated volume controlled ventilation (PRVC), etc. by intermittently releasing (lowering) the intra-airway pressure based on CPAP.
The capacity parameter of the breathing machine is a dynamic physical parameter, and the peak flow rate influences the inspiratory-expiratory ratio, the sigh/deep inspiration, the flow trigger sensitivity and the like; the pressure parameters of the ventilator mainly comprise one or more of inspiratory pressure level, positive end inspiratory pressure, positive end expiratory pressure, mean airway pressure, peak airway pressure, pressure trigger sensitivity and the like.
Therefore, the medicine adding implementation method applied to the lung disease treatment can realize intelligent control of medicine adding in the aerosol therapy according to the received data, further optimize the treatment scheme of the lung disease and be beneficial to improving the treatment effect of the aerosol therapy on the lung disease; in addition, the received data are various, so that the matching degree of the generated medicine adding parameters and the lung diseases of the patient can be improved when medicine adding control is realized, and further the treatment effect of the lung diseases can be further improved; in addition, the intelligent control of multi-path dosing can be realized while the intelligent dosing control is realized, and then the diversified dosing modes are realized.
Example two
Referring to fig. 3, fig. 3 is a schematic flow chart of another medicated implementation method for treating pulmonary diseases according to the embodiment of the present invention. Wherein, the method described in fig. 3 is applied to a dosing implementation system, which at least comprises a dosing control device and a dosing device. As shown in fig. 3, the medicated implementation method applied to the treatment of pulmonary diseases may include the following operations:
201. the dosing control device receives input data.
202. The dosing control device generates dosing control parameters according to the received data, and generates medicine adding parameters according to the dosing control parameters.
203. The medicine adding device receives the medicine adding parameters generated by the medicine adding control device and adds the required medicine into the device to be added according to the medicine adding parameters.
Optionally, the dosing device may comprise at least two dosing branches to achieve multi-way dosing.
Optionally, the medicated implement system may further comprise a device to be medicated. Still further, the dosing device may be provided with an interface connected to the air/air line of the device to be dosed, or the dosing implementation system may further include an interface connected to the air/air line of the device to be dosed.
In an alternative embodiment, the dosing control device may include a dosing controller 30 and a data input interface 40 corresponding to data, in which case, the dosing control device may be as shown in fig. 4, and fig. 4 is a schematic structural diagram of a dosing control device disclosed in the embodiment of the present invention. As shown in fig. 4, when the data includes five data paths, i.e., real-time status data of a patient, working status data of a device to be medicated, real-time status data of atomization, types and particle parameters of medicated drugs, and parameter data of a suction port of the device to be medicated, the medicated control device may include five data input interfaces 40 for respectively receiving the five data paths, and it should be noted that two or more data paths may share one data input interface 40. Wherein, add medicine controller 30 and be used for wireless connection or electric connection charge device, optionally, add medicine controller 30 can concrete connection charge medicine in the charge device every add medicine branch road include add medicine real-time regulation proportion solenoid valve, also can connect the charge medicine in the charge device every add medicine branch road include through the solenoid valve controller and adjust proportion solenoid valve in real time, and charge device is used for connecting the blast pipe/the breathing pipe cross-section of waiting to charge the medicine device.
In an alternative embodiment, each dosing branch 50 comprised by the dosing device may comprise a dosing inlet 501, a dosing real-time proportional regulating solenoid valve 502 corresponding to the dosing inlet 501, and a dosing outlet 503 corresponding to the dosing inlet 501, and the dosing outlet 503 corresponding to the dosing inlet 501 is used for connecting the air/suction pipe section of the device to be dosed. It should be noted that the dosing real-time adjustment proportional solenoid valve 502 corresponding to the dosing inlet 501 may be directly connected to the dosing controller 30 included in the dosing control device, or may be connected to the dosing controller 30 included in the dosing control device through the solenoid valve controller 60, at this time, the dosing real-time adjustment proportional solenoid valve 502 included in each dosing branch 50 is connected to the solenoid valve controller 60, and the structure of the dosing device may be as shown in fig. 5, where fig. 5 is a schematic structural view of the dosing device disclosed in the embodiment of the present invention. It should be noted that the 4 medicated branches included in fig. 5 are only exemplary illustrations, and the number of medicated branches is not limited in the embodiment of the present invention, and may be set according to actual situations.
In this alternative embodiment, each of the dosing branches 50 includes a dosing inlet 501 having one end connected to a dosing inlet of the dosing real-time adjustment proportional solenoid valve 502 corresponding to the dosing inlet 501, a dosing outlet of the dosing real-time adjustment proportional solenoid valve 502 corresponding to the dosing inlet 501 connected to one end of a dosing outlet 503 corresponding to the dosing inlet 501, and the other end of the dosing outlet 503 corresponding to the dosing inlet 501 for connecting to a dosing inlet of an air/air suction tube of the device to be dosed.
In this optional embodiment, it is further optional that the other end of the drug feeding inlet 501 included in each drug feeding branch 50 is used for connecting a dedicated drug storage system of a hospital, and the dedicated drug storage system is equipped with a drug feeding power device capable of linking with a drug feeding control device, so that the drug can be directly linked with the dedicated drug storage system after determining drug adding parameters to realize automatic addition of the drug, thereby reducing human participation and improving the drug adding efficiency and the drug adding accuracy.
In this alternative embodiment, the generating the medicated control parameters by the medicated control device from the received data may comprise:
the dosing controller 30 generates dosing control parameters for the solenoid valve controller 60 to adjust the dosing real-time adjustment proportional solenoid valve 502 included in each dosing branch by real-time processing of the received data based on a medical expert system, a big data processing algorithm, a dosing scheme self-learning algorithm, and a decision optimization algorithm.
In practical application, the dosing controller 30 may call the medical expert database to decide a preferred dosing type according to the multi-channel data, and then adjust the learning algorithm of the dosing parameters (type, dosage, rate, variation, dosing time, etc.) according to the real-time status data of the patient during the treatment process, i.e., modify and adjust the dosing parameters in real time according to the condition of the patient, so as to obtain a decision optimization algorithm capable of achieving a better treatment effect. The medical expert database needs to be called repeatedly, the medical expert database needs to be updated continuously according to the obtained treatment effect, and the learning algorithm and the medical expert database form an optimization scheme decision system for treating patients, so that the final purpose is to improve the treatment rate and reduce the critical rate and the death rate.
It should be noted that, in an alternative embodiment, the above-mentioned electromagnetic valve controller 60 may be a part of the drug adding control device, at this time, the drug adding control device includes, in addition to the drug adding controller 30 and the data access interface 40, an electromagnetic valve controller 60, and the electromagnetic valve controller 60 determines at least one target drug adding branch corresponding to the drug to be added according to the drug adding parameter, and adjusts the drug adding real-time adjusting proportional electromagnetic valve included in each target drug adding branch according to the drug adding parameter, and adds the required drug to the air feed pipe/air suction pipe of the device to be added through the drug adding real-time adjusting proportional electromagnetic valve included in each target drug adding branch, it should be noted that, in consideration of the driving power and the multi-path driving, a dedicated multi-path driver integrated circuit may be additionally provided. In another alternative embodiment, the solenoid controller 60 may be a part of the drug adding device, in this case, the drug adding device may further include the solenoid controller 60 in addition to the plurality of drug adding branches 50, and the drug adding device may add the required drug to the device to be added according to the drug adding parameters, and may include:
the solenoid valve controller 60 determines at least one target medicine adding branch corresponding to the medicine to be added according to the medicine adding parameter, adjusts the medicine adding real-time adjusting proportional solenoid valve included in each target medicine adding branch according to the medicine adding parameter, and adds the required medicine to the air feed pipe/air suction pipe of the medicine adding device through the medicine adding real-time adjusting proportional solenoid valve included in each target medicine adding branch.
In this alternative embodiment, the electromagnetic valve controller 60 utilizes the dosing real-time adjustment proportional electromagnetic valve to finely control the dosing quantity, adjust the start-stop time thereof, and dynamically open the curve of the dosing real-time adjustment proportional electromagnetic valve, and real-time control the dosing time, the dosing quantity, the dosing intensity (flow rate), the variable intensity dosing, and the like, so as to achieve the optimal treatment effect. And the electromagnetic valve controller 60 is controlled by the drug adding controller 30 in the drug adding control device, which realizes the coordination control of the drug adding real-time adjusting proportional electromagnetic valve based on the big data analysis result of the drug adding control device, thereby realizing the atomization drug adding control aiming at optimizing the treatment.
In another alternative embodiment, when the device to be medicated is a respirator, the respirator is provided with a device matching with the medicated, the device matching with the medicated provided on the respirator can be as shown in fig. 6, and 6 is a schematic structural view of the device matching with the medicated provided on the respirator disclosed in the embodiment of the present invention. As shown in fig. 6, the device for matching with the medicine feeding comprises an air inlet branch 70, an air outlet branch 80 and a patient breathing port 90 connected with the air inlet branch 70 and the air outlet branch 80.
As shown in fig. 6, the air inlet branch 70 includes an oxygen inlet 701, an air inlet 702, an air-oxygen mixing portion 703, an air inlet pipe 704, a humidification atomization portion 705, and an air inlet 706 connected to the breathing port 80 of the patient, the air-oxygen mixing portion 703 connects the oxygen inlet 701 and the air inlet 702, the air inlet pipe 704 is provided with an oxygen detection device 707 or a port (not shown in fig. 6) for connecting the oxygen detection device 707, a safety valve 708, a first pressure detection device 709 or a port (not shown in fig. 6) for connecting the first pressure detection device 709, and a port 710 connected to the dosing device, the interface 710 connected with the dosing device is located behind the first pressure detection device 709 or the interface used for connecting the first pressure detection device 709 and in front of the humidification atomization portion 705, the ventilator is connected with the dosing device through the interface 710 connected with the dosing device, and the dosing device can be specifically connected into the ventilator through a flange or a bayonet.
As shown in fig. 6, the air outlet branch 80 includes an air outlet pipe 801, and the air outlet pipe 801 is provided with a second pressure detection device 802 or an interface (not shown in fig. 6) for connecting the second pressure detection device 802, an exhalation valve 803, a flow detection device 804 or an interface for connecting the flow detection device, and an air outlet 805.
In yet another alternative embodiment, the medicated branch of the medicated device may be connected in series to the device to be medicated, may also be connected in parallel to the device to be medicated, and may also be connected in series and parallel to the device to be medicated, which is not limited in the embodiments of the present invention. The medicine feeding branches are connected to the medicine feeding device in parallel, the medicine feeding ports with the same structure are arranged on the same horizontal section of the air supply pipe/air suction pipe or on the cylindrical spiral distribution surface of the air supply pipe/air suction pipe of the medicine feeding device and are connected to the medicine feeding device, the number of the medicine feeding ports is selectable, and the medicine feeding ports and the interface of the air supply pipe/air suction pipe can have an inclination angle, namely the axis of the medicine feeding ports and the axis of the air supply pipe/air suction pipe form an acute angle, so that medicine feeding is smooth. The series connection method can be a flange or a clamping mode, and the connection position needs to be sealed and prevented from leakage.
It can be seen that this optional embodiment provides the combination mode of adding medicine implementation system and ordinary atomizing medical treatment and breathing machine treatment, and charge device adopts the modular structure, and the multistage multiplication of adding the medicine mouth can be realized to the multistage series connection of single module to realize the optimization treatment scheme of mixed medicine, and a plurality of single modules can also realize the parallelly connected medicine scheme that adds of multichannel plane or inclined plane, provide diversified multichannel and add medicine implementation scheme. In addition, when adding medicine when realizing that the system is applied to the breathing machine, only need the position before the humidifying atomizing portion of intake pipe/breathing pipe insert charge device just can realize the reinforcing of breathing machine function, also promptly the breathing machine no longer only provides simple respiratory function for the patient, the function of medication has still been increased, and because original medicine is solid-state particle mostly, position access charge device before the humidifying atomizing portion of intake pipe/breathing pipe can make original medicine and intake pipe/breathing pipe air oxygen gas mixture that comes in mix the back and carry out the humidifying atomizing according to the original route of breathing machine intake pipe/breathing pipe and handle, later get into patient's oronasal or insert the lung trachea. In addition, only need to carry out simple repacking to the intake pipe/breathing pipe of original breathing machine, also the output of intake pipe/breathing pipe and the structural adaptation of original humidifying atomizing portion make standard connected mode, the input of intake pipe/breathing pipe then will be grafted behind the pressure detection point on original pipeline, because intake pipe/breathing pipe is made by medical TPE material, consequently, to adding on the breathing machine with add the device that matches with the medicine or reequip simple accurate to breathing machine, be favorable to realizing the multichannel on the breathing machine and add the medicine. When multi-path dosing is realized on the respirator, positive pressure inspiration of the respirator can be utilized so as to provide aerodynamic force for entering mixed medicine, and if the aerodynamic force meets the requirement of the optimal dosing process, the aerodynamic force needs to be optimized, namely, the medicine adding parameters are modified according to the state variable of an inspiratory pipeline of the respirator so as to achieve the purpose of optimal treatment.
EXAMPLE III
The embodiment of the invention discloses a dosing control device, which is applied to a dosing implementation system, and can comprise a data input interface and a dosing controller, wherein the dosing controller is connected with a dosing device, and optionally, the dosing device comprises at least two dosing branches, wherein:
and the data input interface is used for receiving input data.
And the dosing controller is used for generating dosing control parameters according to the received data and generating medicine adding parameters according to the dosing control parameters, the medicine adding parameters are used for controlling the dosing device to add required medicines into the device to be dosed, and the device to be dosed is a respirator or spray treatment equipment.
The medicine adding parameters comprise one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
It should be noted that, in the embodiment of the present invention, please refer to the description related to the first embodiment or the second embodiment for other descriptions related to the drug administration control device, the drug administration implementation system, the device to be administered, and the like, which are not described in detail herein.
Therefore, the embodiment of the invention can realize intelligent control of dosing in the aerosol therapy according to the received data, further optimize the treatment scheme of the lung diseases and is beneficial to improving the treatment effect of the aerosol therapy on the lung diseases.
Example four
The embodiment of the invention discloses a dosing device, which is connected with a dosing control device, optionally comprises at least two dosing branches, wherein:
the drug adding device is used for receiving the drug adding parameters generated by the drug adding control device and adding the required drug into the device to be added according to the drug adding parameters; the device to be added with the medicine is a respirator or spray therapy equipment, the medicine adding parameters are generated by the medicine adding control device according to the received data, and the medicine adding parameters comprise one or more combinations of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
Optionally, each dosing branch comprises a dosing inlet, a dosing real-time adjusting proportional solenoid valve corresponding to the dosing inlet and a dosing outlet corresponding to the dosing inlet, the dosing real-time adjusting proportional solenoid valve included in each dosing branch is connected with a solenoid valve controller, and the solenoid valve controller is connected with a dosing control device.
The dosing device comprises dosing inlet ports, dosing outlet ports and dosing branch paths, wherein one end of each dosing inlet port, which is included by each dosing branch path, is connected with a dosing inlet corresponding to the dosing inlet port, and the dosing inlet port of each dosing real-time regulation proportional solenoid valve, the dosing outlet port of each dosing real-time regulation proportional solenoid valve, which corresponds to the dosing inlet port, is connected with one end of a dosing outlet corresponding to the dosing inlet port, and the other end of the dosing outlet corresponding to the dosing inlet port is used for being connected with a dosing inlet.
Wherein, the other end of the medicine inlet that every adds medicine branch road includes is used for connecting the special medicine system that stores up of hospital, and special medicine system that stores up is equipped with the medicine power device that adds that can link with medicine controlling means.
It should be noted that, for other descriptions of the drug administration control device, the device to be medicated, and the drug administration device, reference is made to the corresponding descriptions in the first embodiment or the second embodiment, and details of the embodiments of the present invention are not repeated.
Therefore, the embodiment of the invention can realize intelligent control of dosing or multi-path dosing in the aerosol therapy according to the received data, further optimize the treatment scheme of the lung diseases and is beneficial to improving the treatment effect of the aerosol therapy on the lung diseases; in addition, the received data are various, so that the matching degree of the generated medicine adding parameters and the lung diseases of the patient can be improved when medicine adding control is realized, and further the treatment effect of the lung diseases can be further improved; in addition, the dosing control can be realized based on the electromagnetic valve controller and the dosing real-time adjusting proportional electromagnetic valve, so that the dosing efficiency and the control accuracy are improved; in addition, the dosing device adopts a modular design, a plurality of single modules can realize dosing in a serial, parallel or serial and parallel combined mode, a diversified dosing realization mode is provided, and the multi-stage serial connection of the single modules can realize multi-stage multiplication of a dosing port, thereby being beneficial to realizing an optimized treatment scheme of mixed dosing; in addition, when the medicine adding device is applied to a respirator, the medicine adding device is connected in front of the humidifying and atomizing part of the air inlet pipe/the air suction pipe, so that the function of the respirator can be improved, namely, the function of only providing breathing is upgraded into the function of medicine treatment.
The above-described embodiments of the apparatus are merely illustrative, and the modules described as separate components may or may not be physically separate, and the components shown as modules may or may not be physical modules, may be located in one place, or may be distributed on a plurality of network modules. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution of the present embodiment. One of ordinary skill in the art can understand and implement it without inventive effort.
Through the above detailed description of the embodiments, those skilled in the art can clearly understand the specific implementation method of the embodiments: the dosing controller takes a single chip microcomputer with a strong data processing function as a hardware core under the support of an interface circuit, a communication circuit with external related equipment, a power supply circuit, a driving circuit and other hardware circuits, software programming is the key of strong control function and more flexible applicability, the dosing controller comprises a series of contents such as data processing analysis, expert system interpretation, learning algorithm, optimized adjustment of dosing parameters and the like, software reflects the dosing and medical decision level and can be updated in real time, and the optimized software based on a hardware platform can improve the treatment rate and reduce the critical rate and the death rate.
Finally, it should be noted that: the present invention discloses a method and a device for implementing drug administration for treating pulmonary diseases, which are only preferred embodiments of the present invention, and are only used for illustrating the technical solutions of the present invention, not for limiting the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those skilled in the art; the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims (14)

1. A dosing implementation method applied to treatment of pulmonary diseases is applied to a dosing implementation system, the dosing implementation system at least comprises a dosing control device, and the method comprises the following steps:
the drug adding control device receives input data;
the drug adding control device generates drug adding control parameters according to the received data, and generates drug adding parameters according to the drug adding control parameters, the drug adding parameters are used for controlling the drug adding device to add required drugs into the device to be added, and the device to be added is a respirator or spray treatment equipment;
the medicine adding parameters comprise one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
2. The method for achieving drug addition in pulmonary disease treatment according to claim 1, wherein the data comprises one or more of real-time status data of the patient, working status data of the device to be added, real-time status data of atomization, drug type and particle parameters to be added, and parameters data of the inhalation port of the device to be added.
3. The medicated implement method for the treatment of pulmonary diseases according to claim 1 or 2, wherein the medicated implement system further comprises the medicated device and/or the device to be medicated,
and, the method further comprises:
the medicine adding device receives the medicine adding parameters generated by the medicine adding control device and adds the required medicine into the device to be added according to the medicine adding parameters.
4. The medicated implement method for pulmonary disease treatment according to claim 1 or 2, wherein the medicated device comprises at least two medicated branches.
5. The drug adding implementation method applied to the treatment of the pulmonary disease according to claim 4, wherein each drug adding branch comprises a drug adding inlet, a drug adding real-time adjusting proportional solenoid valve corresponding to the drug adding inlet, and a drug adding outlet corresponding to the drug adding inlet, and the drug adding real-time adjusting proportional solenoid valve included in each drug adding branch is connected with a solenoid valve controller;
one end of the dosing inlet of each dosing branch is connected with a dosing inlet of a dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet, a dosing outlet of the dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet is connected with one end of a dosing outlet corresponding to the dosing inlet, and the other end of the dosing outlet corresponding to the dosing inlet is used for being connected with a dosing inlet of an air pipe/air suction pipe of the device to be dosed;
the other end of the drug feeding inlet of each drug feeding branch is connected with a special drug storage system of a hospital, and the special drug storage system is provided with a drug feeding power device which can be linked with the drug feeding control device.
6. The method of claim 5, wherein the medicated control device comprises a medicated controller and a data input interface corresponding to the data; the dosing controller is connected with the electromagnetic valve controller;
wherein, add medicine controlling means according to the data generation that receive add medicine control parameter, include:
the dosing controller generates dosing control parameters for the solenoid valve controller to adjust dosing real-time adjusting proportional solenoid valves included in each dosing branch through real-time processing of the received data based on a medical expert system, a big data processing algorithm, a dosing scheme self-learning algorithm and a decision optimization algorithm.
7. The medicated implementation method applied to the treatment of pulmonary diseases of claim 6, wherein the medicated device comprises the solenoid valve controller, or the medicated control device comprises the solenoid valve controller;
when the medicine adding device comprises the electromagnetic valve controller, the medicine adding device adds the required medicine into the device to be added according to the medicine adding parameters, and the medicine adding device comprises:
the electromagnetic valve controller determines at least one target medicine adding branch corresponding to the medicine to be added according to the medicine adding parameters, adjusts the medicine adding real-time adjusting proportion electromagnetic valve included in each target medicine adding branch according to the medicine adding parameters, and adds the required medicine to the air feed pipe/air suction pipe of the medicine adding device through the medicine adding real-time adjusting proportion electromagnetic valve included in each target medicine adding branch.
8. The method for achieving drug addition for pulmonary disease treatment according to claim 7, wherein when the device to be added is the ventilator, a device matched with drug addition is provided on the ventilator, and the device matched with drug addition comprises an air inlet branch, an air outlet branch and a patient breathing port connected with the air inlet branch and the air outlet branch;
the air inlet branch comprises an oxygen inlet, an air-oxygen mixing part, an air inlet pipe, a humidifying and atomizing part and an air inlet connected with the breathing port of the patient, the air-oxygen mixing part is connected with the oxygen inlet and the air inlet, the air inlet pipe is provided with an oxygen detection device or a port used for connecting the oxygen detection device, a safety valve, a first pressure detection device or a port used for connecting the first pressure detection device, and a port connected with the dosing device, the port connected with the dosing device is positioned behind the first pressure detection device or the port used for connecting the first pressure detection device and in front of the humidifying and atomizing part, and the respirator is connected with the dosing device through the port connected with the dosing device;
the air outlet branch comprises an air outlet pipe, and a second pressure detection device or a connector, an expiratory valve and a flow detection device which are used for connecting the second pressure detection device or a connector and an air outlet which are used for connecting the flow detection device are arranged on the air outlet pipe.
9. The method for achieving drug administration in pulmonary disease treatment according to claim 8, wherein the drug administration device comprises all the drug administration branches connected in series to the drug to be administered, or connected in parallel to the drug to be administered, or connected in series and parallel to the drug to be administered.
10. The method for achieving drug feeding in pulmonary disease treatment as claimed in claim 9, wherein the drug feeding branch is connected in parallel to the device to be medicated by disposing drug feeding ports with the same structure on the same horizontal cross section of the air/air suction pipe of the device to be medicated or on the cylindrical spiral distribution surface of the air/air suction pipe of the device to be medicated, and the drug feeding ports and the air/air suction pipe ports of the device to be medicated have an inclination angle.
11. The dosing control device is characterized by being applied to a dosing implementation system and comprising a data input interface and a dosing controller; the dosing controller is connected with the dosing device; wherein:
the data input interface is used for receiving input data;
the dosing controller is used for generating dosing control parameters according to the received data and generating medicine adding parameters according to the dosing control parameters, the medicine adding parameters are used for controlling a dosing device to add required medicines into a device to be dosed, and the device to be dosed is a respirator or spray treatment equipment;
the medicine adding parameters comprise one or more of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding rate of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
12. The utility model provides a medicine adding device which characterized in that, medicine adding device is connected with medicine adding control device, wherein:
the drug adding device is used for receiving the drug adding parameters generated by the drug adding control device and adding the required drug into the device to be added according to the drug adding parameters; the device to be added with the medicine is a respirator or spray therapy equipment, the medicine adding parameters are generated by the medicine adding control device according to received data, and the medicine adding parameters comprise one or more combinations of the medicine type of the medicine to be added, the medicine adding amount of the medicine to be added, the medicine adding speed of the medicine to be added, the medicine adding time period of the medicine to be added, the medicine adding frequency of the medicine to be added and the medicine adding change condition.
13. The medicated device of claim 12, wherein the medicated device comprises at least two medicated branches.
14. The dosing device according to claim 13, wherein each dosing branch comprises a dosing inlet, a dosing real-time adjustment proportional solenoid valve corresponding to the dosing inlet, and a dosing outlet corresponding to the dosing inlet, and the dosing real-time adjustment proportional solenoid valve of each dosing branch is connected to a solenoid valve controller, and the solenoid valve controller is connected to the dosing control device;
one end of the dosing inlet of each dosing branch is connected with a dosing inlet of a dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet, a dosing outlet of the dosing real-time regulation proportional solenoid valve corresponding to the dosing inlet is connected with one end of a dosing outlet corresponding to the dosing inlet, and the other end of the dosing outlet corresponding to the dosing inlet is used for being connected with a dosing inlet of an air pipe/air suction pipe of the device to be dosed;
the other end of the drug feeding inlet of each drug feeding branch is connected with a special drug storage system of a hospital, and the special drug storage system is provided with a drug feeding power device which can be linked with the drug feeding control device.
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Application publication date: 20201016