CN111772920A - Glaucoma drainage device and drainage implant therefor - Google Patents

Glaucoma drainage device and drainage implant therefor Download PDF

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Publication number
CN111772920A
CN111772920A CN202010747071.3A CN202010747071A CN111772920A CN 111772920 A CN111772920 A CN 111772920A CN 202010747071 A CN202010747071 A CN 202010747071A CN 111772920 A CN111772920 A CN 111772920A
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CN
China
Prior art keywords
glaucoma drainage
drainage implant
wall
cylindrical
groove
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Pending
Application number
CN202010747071.3A
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Chinese (zh)
Inventor
阚敏
王燕涛
梁远波
王琰
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Suzhou Langmu Medical Technology Co.,Ltd.
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Shenzhen Langmu Medical Technology Co ltd
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Filing date
Publication date
Application filed by Shenzhen Langmu Medical Technology Co ltd filed Critical Shenzhen Langmu Medical Technology Co ltd
Publication of CN111772920A publication Critical patent/CN111772920A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00781Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment

Abstract

The application provides a glaucoma drainage implant, glaucoma drainage implant includes the cylindrical pipeline of cavity type, and the pipe wall outside of cylindrical pipeline is provided with the friction that increases frictional resistance along length direction and increases the structure and lead to the groove, leads to the outside length direction setting of pipe wall of groove along cylindrical pipeline, leads to the groove and makes the inside of cylindrical pipeline link up with the external world in order to increase aqueous humor flow area from the side, and the width that leads to the groove is 20um-130 um. The application still provides a glaucoma drainage device, the glaucoma drainage device and glaucoma drainage implant thereof of this application, sets up the friction increase structure through the outer wall at cylindrical pipeline and makes the frictional force increase between glaucoma drainage implant and the schlemm pipe to avoid removing, long-term treatment is effectual, and aqueous humor flow area is big.

Description

Glaucoma drainage device and drainage implant therefor
Technical Field
The application relates to the technical field of medical equipment, in particular to a glaucoma drainage device and a drainage implant thereof.
Background
Glaucoma (glaucoma) is a group of diseases characterized by atrophy and depression of the optic papilla, visual field loss and visual deterioration, pathological increased intraocular pressure and insufficient blood supply to the optic nerve are primary risk factors of the onset of the glaucoma, and the tolerance of the optic nerve to pressure damage is also related to the occurrence and development of the glaucoma. Obstruction of any ring in the aqueous humor circulatory pathway can lead to pathological changes caused by elevated intraocular pressure, but some patients also present with normal tension glaucoma. Glaucoma is one of three major blinding diseases causing blindness in humans, with a total incidence of 1% and 2% after age 45. Clinically, glaucoma is classified into three major categories, primary, secondary and congenital, according to etiology, angle of the atrium, tonography and the like.
In the prior art, it is common to implant a drainage implant inside the eye of the human body to reestablish an aqueous humor outflow pathway, thereby lowering intraocular pressure for therapeutic purposes. However, the drainage implants in the prior art are generally unstable and easy to move after being implanted into schlemm tubes, and aqueous humor only flows through openings at two ends of the implants, so that the flow area is small.
Disclosure of Invention
The application provides a glaucoma drainage device and drainage implant thereof to solve the problem that the drainage implant easily moves among the prior art.
In order to solve the technical problem, the application adopts a technical scheme that: the utility model provides a glaucoma drainage implant, glaucoma drainage implant includes the cylindrical pipeline of cavity type, and the pipe wall outside of cylindrical pipeline is provided with the friction that increases frictional resistance along length direction and increases the structure and lead to the groove, leads to the outside length direction setting of pipe wall of groove edge cylindrical pipeline, leads to the groove and makes the inside of cylindrical pipeline link up with the external world in order to increase aqueous humor flow area from the side, and the width that leads to the groove is 20um-130 um.
The friction increasing structure comprises a plurality of concave holes arranged at intervals, and the concave holes are distributed on the outer portion of the pipe wall of the cylindrical pipeline.
Wherein, the shrinkage pool link up with the inside of cylindrical pipeline.
Wherein the friction increasing structure comprises a plurality of annular grooves arranged along the circumference of the cylindrical pipe.
Wherein the friction increasing structure comprises a first helical groove around the outside of the tube wall of the cylindrical tube.
The friction increasing structure further comprises a second spiral groove surrounding the outer portion of the pipe wall of the cylindrical pipe, and the first spiral groove and the second spiral groove are arranged in a crossed mode.
Wherein the friction increasing structure comprises a plurality of protrusions protruding along an outer wall of the cylindrical pipe.
Wherein each of the protrusions includes an inclined portion extending obliquely outward from the outer wall of the cylindrical pipe and a horizontal portion bent from an end of the inclined portion away from the outer wall, the horizontal portion being maintained in parallel with the outer wall.
Wherein the glaucoma drainage implant is made of titanium alloy material, and the curvature of the cylindrical pipeline is matched with the curvature of a schlemm tube of the eye.
In order to solve the above technical problem, another technical solution adopted by the present application is: a glaucoma drainage device is provided that includes a glaucoma drainage implant as described above.
The beneficial effect of this application is: be different from prior art's condition, the application provides a glaucoma drainage device and glaucoma drainage implant thereof, makes the frictional force increase between glaucoma drainage implant and the schlemm pipe through set up friction increase structure at the outer wall of cylindrical pipeline to avoid removing, long-term treatment is effectual.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the application, the drawings that are needed to be used in the description of the embodiments are briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the application, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
fig. 1 is a schematic perspective view of a first embodiment of a glaucoma drainage implant of the present application;
fig. 2 is a schematic cross-sectional view of the glaucoma drainage implant shown in fig. 1;
fig. 3 is a schematic perspective view of a second embodiment of a glaucoma drainage implant of the present application;
fig. 4 is a schematic cross-sectional view of the glaucoma drainage implant shown in fig. 3;
fig. 5 is a schematic perspective view of a third embodiment of a glaucoma drainage implant of the present application;
fig. 6 is a schematic perspective view of a fourth embodiment of a glaucoma drainage implant of the present application;
fig. 7 is an enlarged schematic view of portion a of the glaucoma drainage implant shown in fig. 6;
fig. 8 is a perspective view of a fifth embodiment of a glaucoma drainage implant of the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any inventive step based on the embodiments in the present application, are within the scope of protection of the present application.
Referring to fig. 1 and 2, fig. 1 is a schematic perspective view of a first embodiment of a glaucoma drainage implant according to the present application, and fig. 2 is a schematic cross-sectional view of the glaucoma drainage implant shown in fig. 1. In this embodiment, the glaucoma drainage implant comprises a curved hollow cylindrical tube 10, the curvature of the cylindrical tube 10 matching the curvature of the schlemm's canal of the eye, the length of the cylindrical tube 10 being 0.5mm to 7mm, the inner diameter of the cylindrical tube 10 being 30um to 200um and the outer diameter being 220um to 350 um. Because of the glaucoma drainage implant is finally implanted in the schlemm tube, the curvature of the glaucoma drainage implant is set to be matched with the schlemm tube in the embodiment, and compared with the pipeline in the prior art, the glaucoma drainage implant is linear, so that the drainage effect is better, and discomfort of eyes can be avoided. The cylindrical tube 10 is further preferably 1mm-3mm, and the glaucoma drainage implant with the size is smaller than the size of the implant in the prior art, so that the implantation difficulty is reduced, the implantation success rate is improved, and the glaucoma drainage implant can be implanted in the opposite directions of the implantation opening according to requirements. Further preferred are an inner diameter of 180um to 190um, which is capable of ensuring sufficient aqueous humor drainage, and an outer diameter of 30um to 35um, which is capable of ensuring the overall strength of the glaucoma drainage implant while having a moderate weight.
In the present embodiment, the pipe wall outer portion of the cylindrical pipe 10 is provided with a friction increasing structure that increases frictional resistance in the length direction. Usually, the outer wall of the implant pipeline in the prior art is smooth, so that the implant pipeline can move after being implanted, and the friction is increased by arranging a friction increasing structure on the outer part of the tube wall of the glaucoma drainage implant of the embodiment, so that the implanted movement can be avoided, and the implant is always kept at the optimal drainage position during implantation.
In this embodiment, the friction increasing structure comprises a plurality of recesses 20 arranged at intervals, and the recesses 20 are distributed over the outer portion of the pipe wall of the cylindrical pipe. The well 20 is preferably circular, the aperture of the circular well 20 is preferably 50um to 150um, and the distance between each well is preferably maintained to be 100um to 500 um. Of course, in other embodiments, the concave hole 20 may have other shapes such as a square shape, which is not limited in this application. Preferably, shrinkage pool 20 link up with the inside of cylindrical pipeline, and the structure after linking up can make aqueous humor flow from linking up, increases drainage effect.
Referring to fig. 3 and 4, fig. 3 is a schematic perspective view of a second embodiment of a glaucoma drainage implant according to the present application; fig. 4 is a schematic cross-sectional view of the glaucoma drainage implant shown in fig. 3. The glaucoma drainage implant of this embodiment is identical in basic structure to the previous embodiment, except for the friction increasing structure. In the present embodiment, the friction increasing structure includes a plurality of annular grooves 30 disposed circumferentially along the cylindrical pipe 100. A plurality of annular grooves 30 parallel arrangement, the groove width of annular groove 30 is preferred 10um-100um, the groove height of annular groove 30 is preferred 5um-50um, the interval of adjacent annular groove 30 is preferred 20um-100um, further preferred groove width is 85um-95um, the groove height is 40um-45um, the interval of adjacent annular groove 30 is 40um-50um, this combination parameter is on the basis that can guarantee the intensity of glaucoma drainage implant, the drainage is effectual, and the steadiness is good, glaucoma drainage implant can not produce the slip after implanting schlemm's pipe.
Referring to fig. 5, fig. 5 is a schematic perspective view of a glaucoma drainage implant according to a third embodiment of the present invention. The glaucoma drainage implant of this embodiment is identical in basic structure to the first embodiment, except for the friction increasing structure. The friction increasing structure of this embodiment includes a first helical groove 41 around the outside of the pipe wall of the cylindrical pipe 1000 and a second helical groove 42 around the outside of the pipe wall of the cylindrical pipe 1000. Among them, the first spiral groove 41 and the second spiral groove 42 are preferably arranged to intersect. It will be appreciated that if only the first helical groove 41 were provided, there would be a possibility of rotation in one direction after implantation of the glaucoma drainage implant in the schlemm's canal, resulting in poor drainage, due to the helical groove rotating in one direction. In the embodiment, the first spiral groove 41 and the second spiral groove 42 which are arranged in a crossed manner are arranged, so that the glaucoma drainage implant can be prevented from moving by means of the friction force of the crossed grooves after being implanted into the schlemm tube, and the stability is ensured.
Referring to fig. 6 and 7 in combination, fig. 6 is a schematic perspective view of a fourth embodiment of a glaucoma drainage implant according to the present application, and fig. 7 is an enlarged schematic view of a portion a of the glaucoma drainage implant shown in fig. 6. The glaucoma drainage implant of this embodiment is identical in basic structure to the first embodiment, except for the friction increasing structure. The friction increasing structure of this embodiment includes a plurality of protrusions 50 protruding along the outer wall of the cylindrical pipe 2000. Specifically, each protrusion 50 includes an inclined portion 51 extending obliquely outward from the outer wall of the cylindrical tube 2000 and a horizontal portion 52 bent from an end of the inclined portion 51 away from the outer wall, and the horizontal portion 52 is parallel to the outer wall, which is advantageous in that the inclined portion 51 is disposed to reduce the distance from the glaucoma drainage implant to the schlemm's canal and increase friction, and the horizontal portion 52 can be smoothly movably coupled to the inner wall of the schlemm's canal, which can protect the schlemm's canal while friction is secured, compared to the case where only the inclined portion 51 may cut the schlemm's canal. In the present embodiment, the outward inclination direction of each protrusion 50 is the same, but the plurality of protrusions may be left and right, the left half being inclined in one direction and the right half being inclined in the opposite direction, so that the friction force in both directions is increased, or the adjacent protrusions 50 may be inclined in opposite directions, thereby achieving the same effect. Preferably, the distance interval of each protrusion 50 is 50um-500um, the angle between the inclined portion 51 and the outer wall of the cylindrical pipe 2000 is 15 degrees to 60 degrees, the length of the inclined portion 51 is 15um-40um, and the length of the horizontal portion 52 is 5um-20 um.
Among them, the glaucoma drainage implant of the present application is preferably made of a titanium alloy material in order to achieve better biocompatibility.
Referring to fig. 8, fig. 8 is a schematic perspective view of a fifth embodiment of a glaucoma drainage implant according to the present application. In the present embodiment, the difference between the present embodiment and the foregoing embodiments is that the present embodiment has a through groove, and the friction increasing structure can refer to the foregoing embodiments, and the friction increasing structure of the third embodiment is taken as an example for description, the friction-increasing structure of this embodiment includes a first spiral groove 241 around the outside of the tube wall of the cylindrical tube 2000 and a second spiral groove 242 around the outside of the tube wall of the cylindrical tube 2000, the first spiral groove 241 and the second spiral groove 242 being arranged alternately, and in addition, the glaucoma drainage implant further includes a through groove 60, the through groove 60 being arranged along the length direction of the outside of the tube wall of the cylindrical tube 2000, the through groove making the inside of the cylindrical tube 2000 communicate with the outside from the side to increase the aqueous humor flow area, the width of the through groove 60 being 20um to 130um, through the arrangement, the aqueous humor can be circulated with the schlemm pipe through the through groove 60. In this embodiment, the through-slots 60 extend through the entire length of the cylindrical duct 2000, but in other embodiments, the through-slots 60 may be provided to occupy only one-half, or two-thirds, of the length of the cylindrical duct 2000.
Preferably, the through-slot 60 is not linear as shown in fig. 8, but may be curved, for example, when the friction-increasing structure is recessed, the through-slot 60 needs to be disposed to avoid the recessed hole.
It is worth mentioning that the glaucoma drainage implant generates debris and the like in the processing process, and the glaucoma drainage implant injection solution needs to be cleaned, but the inner wall of the cylindrical pipeline 2000 is very difficult to clean due to the excessively small size of the glaucoma drainage implant, and the inventor of the application not only improves the aqueous humor drainage effect, but also finds that the inner wall can be cleaned by the injection solution through the through groove 60, and the cleaning difficulty and cost are greatly reduced.
The structure of the glaucoma drainage implant is described above, and the implantation process is described below:
firstly, performing incision operation on the tube wall of the schlemm tube, secondly, implanting the glaucoma drainage implant of the embodiment in two opposite directions at the incision respectively, wherein the glaucoma drainage implant can prop up the schlemm tube, so that aqueous humor naturally flows in and out from two ends of a cylindrical tube and a through groove of the glaucoma drainage implant, and the glaucoma drainage implant can be stably fixed on the inner wall of the schlemm tube due to the friction increasing structure for increasing friction force.
The application also provides a glaucoma drainage device, which comprises an injector and the glaucoma drainage implant of any one of the embodiments, and the volume of the glaucoma drainage implant is very small, so that the injector is required to be used for precisely implanting the glaucoma drainage implant, and the structure of the injector is not limited because the protection point of the application is the glaucoma drainage implant.
The beneficial effect of this application is: be different from prior art's condition, the application provides a glaucoma drainage device and glaucoma drainage implant thereof, through setting up glaucoma drainage implant to the cylindrical pipeline of cavity type that the curvature matches with schlemm pipe curvature, and set up its length into 0.5mm-7mm, shortened the length of glaucoma drainage implant greatly, reduce the implantation degree of difficulty, improve and implant the success rate. And by providing a friction increasing structure that increases frictional resistance, the glaucoma drainage implant can be held firmly in the schlemm tube implantation position for a long period of time.
It should be noted that if directional indications (such as up, down, left, right, front, and back … …) are referred to in the embodiments of the present application, the directional indications are only used to explain the relative positional relationship between the components, the movement situation, and the like in a specific posture (as shown in the drawings), and if the specific posture is changed, the directional indications are changed accordingly.
In addition, if there is a description of "first", "second", etc. in the embodiments of the present application, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present application.
The above embodiments are merely examples and are not intended to limit the scope of the present disclosure, and all modifications, equivalents, and flow charts using the contents of the specification and drawings of the present disclosure or those directly or indirectly applied to other related technical fields are intended to be included in the scope of the present disclosure.

Claims (10)

1. The utility model provides a glaucoma drainage implant, its characterized in that, glaucoma drainage implant includes the cylindrical pipeline of cavity type, the outside friction that is provided with increase frictional resistance along length direction of the pipe wall of cylindrical pipeline increases the structure and leads to the groove, it follows to lead to the groove the outside length direction of pipe wall of cylindrical pipeline sets up, it makes to lead to the groove the inside edgewise of cylindrical pipeline link up with external world in order to increase aqueous humor flow area, the width that leads to the groove is 20um-130 um.
2. The glaucoma drainage implant of claim 1 wherein the friction increasing structure comprises a plurality of spaced apart recesses extending over the exterior of the wall of the cylindrical conduit.
3. The glaucoma drainage implant of claim 2 wherein the recessed hole communicates with the interior of the cylindrical conduit.
4. The glaucoma drainage implant of claim 1 wherein the friction increasing structure comprises a plurality of annular grooves disposed circumferentially along the cylindrical conduit.
5. The glaucoma drainage implant of claim 1 wherein the friction increasing structure comprises a first helical groove around the exterior of the wall of the cylindrical tube.
6. The glaucoma drainage implant of claim 5 wherein the friction increasing structure further comprises a second helical groove around the exterior of the wall of the cylindrical tube, the first helical groove being disposed crosswise to the second helical groove.
7. The glaucoma drainage implant of claim 1 wherein the friction increasing structure comprises a plurality of protrusions projecting along the outer wall of the cylindrical tube.
8. The glaucoma drainage implant of claim 7 wherein each of the projections includes an inclined portion extending obliquely outward from the outer wall of the cylindrical conduit and a horizontal portion bent from an end of the inclined portion remote from the outer wall, the horizontal portion remaining parallel to the outer wall.
9. The glaucoma drainage implant of any one of claims 1 to 8 where the glaucoma drainage implant is a titanium alloy material and the curvature of the cylindrical tube matches the curvature of the schlemm's canal of the eye.
10. A glaucoma drainage device comprising a glaucoma drainage implant according to any one of claims 1 to 9.
CN202010747071.3A 2020-07-22 2020-07-29 Glaucoma drainage device and drainage implant therefor Pending CN111772920A (en)

Applications Claiming Priority (2)

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CN202010712566 2020-07-22
CN2020107125662 2020-07-22

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CN202010923110.0A Active CN111803274B (en) 2020-07-22 2020-09-04 Glaucoma drainage device and drainage implant thereof

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