CN111714244A

CN111714244A - Experimental mouse fixer

Info

Publication number: CN111714244A
Application number: CN202010663218.0A
Authority: CN
Inventors: 张玲; 杨柳; 蒋波; 王旖; 孙媛之; 彭羿杰
Original assignee: Chongqing Institute for Food and Drug Control
Current assignee: Chongqing Institute for Food and Drug Control
Priority date: 2020-07-10
Filing date: 2020-07-10
Publication date: 2020-09-29

Abstract

The invention discloses an experimental mouse fixer, which comprises a fixed flat plate (1), wherein a flip cylinder is arranged on the fixed flat plate (1), the flip cylinder comprises a head flip cylinder (2) and a trunk flip cylinder (3), and the head flip cylinder (2) is arranged at one end of the trunk flip cylinder (3); one end of the head flip cylinder (2) is rotationally connected with the fixed flat plate (1), and one end of the trunk flip cylinder (3) is rotationally connected with the fixed flat plate (1); the fixing flat plate (1) below the projection of the trunk flip cylinder (3) is provided with a plurality of slots (4) and further comprises an inserting piece (6), and the inserting piece (6) is used for being inserted into any one slot (4); the fixed flat plate (1), the head flip cylinder (2), the trunk flip cylinder (3) and the inserting piece (6) are all transparent acrylic plates; the trunk flip cylinder body (3) is provided with a plurality of hollow parts. The experiment mouse fixer of this scheme of adoption design has the characteristics of being convenient for experiment operation and operation safety.

Description

Experimental mouse fixer

Technical Field

The invention relates to an auxiliary appliance for experimental animals, in particular to an experimental mouse fixer.

Background

The experimental mouse is one of the most commonly used animal models in biomedical experiments, and related experimental information useful for human bodies is obtained through researching the mechanism and the rule of the experimental mouse in the aspects of pharmacology, pathology, toxicology and the like. However, most students in colleges and universities and technical staff in research institutes need to perform fixing operation on the laboratory mouse before the experiment. For example, in the stomach irrigation operation of a rat, the rat becomes violent and irritative due to the fierce sexual condition and the experimental stimulation, the rat is caught by bare hands, the rat is easy to bite or scratch, and the stimulation to the rat is large, so that the experimental result can be influenced. Some drug effect observation experiments of drug administration through the tail vein or tail vein blood collection can also bring influence to the experimental result due to anesthesia, and in addition, the existing fixator can not provide the requirement of the bare back required by the application experiment, and the problem of excrement excretion of experimental mice is not considered.

Therefore, the technical personnel in the field are dedicated to develop the laboratory mouse fixer which is convenient for laboratory operation and ensures the operation safety.

Disclosure of Invention

In view of the above-mentioned defects of the prior art, the present invention is to provide a laboratory mouse fixer, which can fix a laboratory mouse well in the operation of animal experiments and is convenient for the operation of experiments.

In order to achieve the purpose, the invention provides an experimental mouse fixer, which comprises a fixed flat plate, wherein a flip cylinder is arranged on the fixed flat plate, the flip cylinder comprises a head flip cylinder and a trunk flip cylinder, and the head flip cylinder is arranged at one end of the trunk flip cylinder; one end of the turnover cover cylinder body is rotationally connected with the fixed flat plate, and one end of the trunk turnover cover cylinder body is rotationally connected with the fixed flat plate; the fixing flat plate below the projection of the trunk flip cylinder is provided with a plurality of slots and also comprises an inserting piece, and the inserting piece is inserted into any one slot; the fixed flat plate, the head flip cylinder, the trunk flip cylinder and the inserting piece are all transparent acrylic plates; the trunk flip barrel is provided with a plurality of hollow parts.

Further, the bottom of the inserting piece is provided with a fixing rod, two ends of the fixing rod are provided with buckles, and the buckles extend into the slots on two sides of the slot where the inserting piece is located and are clamped on the end faces of the inserting slot.

Furthermore, the inserting pieces are semicircular or arc-shaped.

Furthermore, a round hole is arranged on the inserting piece.

Further, be equipped with many pairs of fixed plates on the fixed flat board that head flip barrel and truck flip barrel activity one end correspond, the fixed plate includes fixed block and backup pad, all be equipped with the screw in fixed block and the backup pad, be equipped with set screw in the screw.

Furthermore, suction cups are arranged at four corners of the bottom surface of the fixed flat plate.

Further, a magnifier is arranged on the trunk flip cylinder far away from one end of the head flip cylinder, and one end part of the magnifier is movably connected with the trunk flip cylinder.

Further, a handle is arranged in the middle of the top of the trunk flip cylinder body.

Further, the handle is an elastic band handle with four finger holes.

Furthermore, the trunk flip cylinder body and the head flip cylinder body are semicircular or arc-shaped cylinder bodies, a first adjusting insertion hole is formed in the fixed flat plate corresponding to the free end of the trunk flip cylinder body, and the cylinder body edge of the trunk flip cylinder body can be inserted into the first adjusting insertion hole; and a second adjusting jack is arranged on the fixed flat plate corresponding to the free end of the head flip cylinder, and the cylinder edge of the head flip cylinder can be inserted into the second adjusting jack.

The invention has the beneficial effects that: open head flip barrel and trunk flip barrel, place the laboratory mouse on fixed flat board, the head of laboratory mouse is fixed by upset head flip barrel, and the health of laboratory mouse is fixed by upset trunk flip barrel to lock through set screw. A plurality of hollow parts are arranged on the trunk flip cylinder body and used for experiment operation. Wherein, according to the difference of laboratory mouse length, select the position of installation inserted sheet to buckle through inserted sheet bottom installation dead lever both ends is fixed in the slot of both sides. The middle part of the insertion piece is provided with a round hole, and the round hole is used for extending out the tail part of the laboratory mouse, so that tail vein injection is facilitated. The four fingers are provided with handles to facilitate the people to take the fixator for the gastric lavage operation. The plurality of slots on the fixing flat plate can also be used for intraperitoneal injection operation and excretion of experimental mice. Be equipped with the magnifying glass on the truck flip barrel and be convenient for experiment observation, swing joint's magnifying glass can circumferential direction, improves the accuracy of experiment rat caudal vein operation.

Drawings

FIG. 1 is a perspective view of the experimental mouse holder of the present invention;

FIG. 2 is a bottom perspective view of the laboratory mouse holder according to the present invention;

FIG. 3 is a side view of the laboratory mouse holder of the present invention;

FIG. 4 is a bottom view of the mouse holder according to the present invention;

FIG. 5 is a schematic view of the insert of the present invention.

Detailed Description

The present invention will be further described with reference to the accompanying drawings and examples, wherein the terms "upper", "lower", "left", "right", "inner", "outer", and the like, as used herein, refer to an orientation or positional relationship indicated in the drawings, which is for convenience and simplicity of description, and does not indicate or imply that the referenced devices or components must be in a particular orientation, constructed and operated in a particular manner, and thus should not be construed as limiting the present invention. The terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

As shown in fig. 1 to 5, the present invention provides an experimental mouse fixer, which includes a fixing plate 1, wherein a flip cylinder is disposed on the fixing plate 1, the flip cylinder includes a head flip cylinder 2 and a trunk flip cylinder 3, and the head flip cylinder 2 and the trunk flip cylinder 3 are semicircular cylinders or arc cylinders, that is, the embodiment is preferably a semicircular cylinder. The head turnover cover cylinder 2 is arranged at one end of the trunk turnover cover cylinder 3; one end of the flip cylinder 2 is rotatably connected with the fixed plate 1 through a hinge, and the other end of the flip cylinder 2 is connected with a fixing screw 9 through a fixing plate 8. Similarly, one end of the trunk flip cylinder 3 is rotatably connected with the fixed flat plate 1 through a hinge; the other end of the trunk flip cylinder 3 is connected with a fixing screw 9 through a fixing plate 8. The head turnover cover cylinder body 2 and the trunk turnover cover cylinder body 3 are turned over. The fixing plate (8) comprises a fixing block (8 a) and a supporting plate (8 b), screw holes are formed in the fixing block (8 a) and the supporting plate (8 b), and fixing screws (9) are arranged in the screw holes. Specifically, place the laboratory mouse on fixed flat board, the head of laboratory mouse is fixed by upset head flip barrel, and the health of laboratory mouse is fixed by upset trunk flip barrel, and the edge of head flip barrel and trunk flip barrel inserts respectively between fixed block 8a and the backup pad 8 b.

Be equipped with first regulation jack 14 on the fixed plate 1 of truck flip barrel 3 activity one end, the activity end limit of truck flip barrel 3 can insert in first regulation jack 14, when truck flip barrel was closed, the bobbin side of truck flip barrel inserted in first regulation jack to can be according to the size of laboratory mouse, the bobbin side of selecting truck flip barrel inserts the length of first regulation jack, the volume of truck flip barrel can reduce along with the increase of the bobbin side inserted length of truck flip barrel, so that be applicable to the not equidimension laboratory mouse of size.

Be equipped with second regulation jack 15 on the fixed plate 1 of head flip barrel 2 activity one end, the activity end limit of head flip barrel 2 can insert in second regulation jack 15, when head flip barrel was closed, the bobbin side of head flip barrel inserted in second regulation jack 15 to can be according to the size of laboratory mouse, the bobbin side of selecting head flip barrel inserts the length in the regulation slot, the volume of head flip barrel can reduce along with the increase of the bobbin side male length of head flip barrel, so that be applicable to the laboratory mouse of the not equidimension of head. A first adjustment socket 14 and a second adjustment socket 15 open between the fixed block 8a and the support plate 8 b.

A plurality of slots 4 are arranged on the fixed flat plate 1 below the projection of the trunk flip cylinder 3, the slots 4 are distributed at equal intervals, and the inserting piece 6 can be inserted into any slot 4; the bottom of the inserting piece 6 is provided with a fixing rod 7, the two ends of the fixing rod 7 are provided with buckles 5, and the buckles 5 can extend into the slots 4 on the two sides of the inserting piece 6 and are clamped on the end surfaces of the inserting slots 4. The insert 6 may be semicircular or circular arc shaped. The insert 6 is provided with a round hole 7. According to the difference of experimental mouse length, select the position of installation inserted sheet to buckle through inserted sheet bottom installation dead lever both ends is fixed in the slot of both sides. The middle part of inserted sheet is equipped with round hole 13, and round hole 13 is used for the afterbody of laboratory mouse to stretch out, is convenient for tail vein injection.

Be equipped with a plurality of fretwork portions on truck flip barrel 3, the fretwork portion is including establishing two back fretwork portions 5a that set up at the symmetry of truck flip barrel both sides middle part position, and the available naked laboratory mouse back of back fretwork portion 5a is pasted and is applied the experiment. The front and back of the back hollow part 5a at one side of the movable end of the trunk flip cylinder body are respectively provided with two front trunk hollow parts 5b and a back trunk hollow part 5c for the experiment operation of the front trunk and the back trunk of the experimental mouse. Be close to 3 four corners departments of truck flip barrel and still be equipped with four limbs fretwork portion 5d respectively for laboratory mouse four limbs stretch out and then experiment operation or fixed, one end also is equipped with fretwork portion 2a on head flip barrel 2. Wherein the position of preceding trunk fretwork 5b and back trunk fretwork 5c corresponds two fixed plates 8 on the trunk flip barrel 3, the edge of preceding trunk fretwork 5b and back trunk fretwork 5c is the opening, and the width of preceding trunk fretwork 5b and back trunk fretwork 5c is less than the width of fixed block 8a and backup pad 8b, such design is that preceding trunk fretwork 5b and back trunk fretwork 5c can be used for the experiment operation, and also can be fixed by centre gripping between fixed block 8a and backup pad 8b, when present trunk fretwork 5b and back trunk fretwork 5c are respectively between a pair of fixed block 8a and backup pad 8b, through set screw locking, two fixed plates can press from both sides the edge of preceding trunk fretwork 5b and back trunk fretwork 5c tightly.

Keep away from be equipped with magnifying glass 11 on the truck flip barrel 3 of head flip barrel 2 one end, magnifying glass 11 tip passes through movable bolt with truck flip barrel 3 and is connected. The magnifying glass 11 is convenient for experiment observation, and swing joint's magnifying glass can circumferential direction, improves the accuracy of experiment rat caudal vein operation. The four corners of the bottom surface of the fixed flat plate 1 are provided with the suckers 10, and the suckers 10 can be used for fixing, so that the stability of experimental operation is facilitated.

A handle 12 is arranged at the middle position of the top of the trunk flip cylinder body 3. The handle 12 is an elastic band handle with four finger holes, and the elastic band handle with four finger holes is convenient for a person to take the fixator for gastric lavage operation.

The fixed flat plate, the head flip cylinder, the trunk flip cylinder and the inserting piece are all transparent acrylic plates.

The foregoing detailed description of the preferred embodiments of the invention has been presented. It should be understood that numerous modifications and variations could be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the prior art according to the concept of the present invention should be within the scope of protection defined by the claims.

Claims

1. An experimental mouse fixer is characterized in that: the turnover mechanism comprises a fixed flat plate (1), wherein a turnover cover cylinder body is arranged on the fixed flat plate (1), the turnover cover cylinder body comprises a head turnover cover cylinder body (2) and a trunk turnover cover cylinder body (3), and the head turnover cover cylinder body (2) is arranged at one end of the trunk turnover cover cylinder body (3); one end of the head flip cylinder (2) is rotationally connected with the fixed flat plate (1), and one end of the trunk flip cylinder (3) is rotationally connected with the fixed flat plate (1); a plurality of slots (4) are arranged on the fixed flat plate (1) below the projection of the trunk flip cylinder (3); the plug-in connector also comprises a plug-in sheet (6), wherein the plug-in sheet (6) is used for being inserted into any slot (4); the fixed flat plate (1), the head flip cylinder (2), the trunk flip cylinder (3) and the inserting piece (6) are all transparent acrylic plates; the trunk flip cylinder body (3) is provided with a plurality of hollow parts.

2. The laboratory mouse holder according to claim 1, wherein: the bottom of the inserting piece (6) is provided with a fixing rod (7), the two ends of the fixing rod (7) are provided with buckles (5), and the buckles (5) stretch into the slots (4) on the two sides of the slot (4) where the inserting piece (6) is located and are clamped on the end faces of the inserting piece (4).

3. The laboratory mouse holder according to claim 1 or 2, wherein: the inserting pieces (6) are semicircular or arc-shaped.

4. The laboratory mouse holder according to claim 1 or 2, wherein: and a round hole (13) is formed in the inserting piece (6).

5. The laboratory mouse holder according to claim 1, wherein: be equipped with fixed plate (8) on fixed flat board (1) that head flip barrel (2) and truck flip barrel (3) activity one end correspond, fixed plate (8) are including fixed block (8 a) and backup pad (8 b), all be equipped with the screw on fixed block (8 a) and backup pad (8 b), be equipped with set screw (9) in the screw.

6. The laboratory mouse holder according to claim 1, wherein: and suction cups (10) are arranged at the four corners of the bottom surface of the fixed flat plate (1).

7. The laboratory mouse holder according to claim 5, wherein: keep away from be equipped with magnifying glass (11) on trunk flip barrel (3) of head flip barrel (2) one end, magnifying glass (11) tip and trunk flip barrel (3) swing joint.

8. The laboratory mouse holder according to claim 1, wherein: a handle (12) is arranged in the middle of the top of the trunk flip cylinder body (3).

9. The laboratory mouse holder according to claim 8, wherein: the handle (12) is a four-finger elastic belt handle.

10. The laboratory mouse holder according to claim 5, wherein: the trunk flip cylinder body (3) and the head flip cylinder body (3) are semicircular or arc-shaped cylinder bodies, a first adjusting insertion hole (14) is formed in the fixed flat plate (1) corresponding to the free end of the trunk flip cylinder body (3), and the cylinder body side of the trunk flip cylinder body (3) can be inserted into the first adjusting insertion hole (14); the fixing plate (1) corresponding to the free end of the head flip cylinder (2) is provided with a second adjusting jack (15), and the cylinder edge of the head flip cylinder (2) can be inserted into the second adjusting jack (15).