CN111672002A - Pressure adjusting method and device of breathing machine - Google Patents

Pressure adjusting method and device of breathing machine Download PDF

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Publication number
CN111672002A
CN111672002A CN202010514428.3A CN202010514428A CN111672002A CN 111672002 A CN111672002 A CN 111672002A CN 202010514428 A CN202010514428 A CN 202010514428A CN 111672002 A CN111672002 A CN 111672002A
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pressure
value
reference value
historical
preset
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CN111672002B (en
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姜栋
杜红雷
常敏
兰广雷
庄志
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BMC Medical Co Ltd
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BMC Medical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B30/00—Energy efficient heating, ventilation or air conditioning [HVAC]
    • Y02B30/70—Efficient control or regulation technologies, e.g. for control of refrigerant flow, motor or heating

Abstract

The embodiment of the invention provides a pressure adjusting method and a pressure adjusting device of a breathing machine, wherein the method comprises the following steps: determining a pressure distribution reference value according to historical pressure values in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to historical pressure values, the ratio of a first working time length to the time length of a historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure values which are not greater than the pressure distribution reference value; determining a target pressure range end value of the breathing machine according to the pressure distribution reference value; and setting the working pressure of the breathing machine in the target working period according to the end value of the target pressure range and the pressure distribution reference value. In the embodiment of the invention, the working pressure of the breathing machine in the target working period can be automatically set without manual setting by a user, the pressure setting efficiency can be improved, and the set working pressure can be more adaptive to the user using the breathing machine at present, so that the setting effect is improved.

Description

Pressure adjusting method and device of breathing machine
Technical Field
The invention relates to the technical field of medical treatment, in particular to a pressure adjusting method and device of a breathing machine.
Background
At present, along with the improvement of the health attention degree of people, the use of the breathing machine in the treatment process is more and more common. In order to ensure the working efficiency of the ventilator, the working pressure of the ventilator is often required to be set.
In the prior art, pressure setting is often performed manually according to experience. Thus, the setting efficiency is low.
Disclosure of Invention
The embodiment of the invention provides a method and a device for adjusting pressure of a breathing machine, which aim to solve the problem of low pressure setting efficiency of the breathing machine in the prior art.
In order to solve the above problem, the embodiment of the present invention is implemented as follows:
in a first aspect, an embodiment of the present invention discloses a pressure adjustment method for a ventilator, where the method includes:
determining a pressure distribution reference value according to a historical pressure value in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value;
determining a target pressure range end value of the breathing machine according to the pressure distribution reference value;
and setting the working pressure of the breathing machine in a target working period according to the target pressure range end value and the pressure distribution reference value.
In a second aspect, an embodiment of the present invention discloses a pressure adjustment device for a ventilator, including:
the first determination module is used for determining a pressure distribution reference value according to historical pressure values in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value;
the second determination module is used for determining a target pressure range end value of the breathing machine according to the pressure distribution reference value;
and the setting module is used for setting the working pressure of the breathing machine in a target working period according to the target pressure range end value and the pressure distribution reference value.
In a third aspect, the present invention discloses a ventilator, which includes a processor, a memory, and a computer program stored on the memory and executable on the processor, wherein the computer program, when executed by the processor, implements the steps of the pressure adjustment method of the ventilator according to the first aspect.
In a fourth aspect, the embodiments of the present invention disclose a computer-readable storage medium, on which a computer program is stored, which, when being executed by a processor, implements the steps of the method for pressure regulation of a ventilator according to the first aspect.
In the embodiment of the invention, a pressure distribution reference value is determined according to historical pressure values in at least one historical effective working period of a breathing machine; the pressure distribution reference value belongs to historical pressure values, the ratio of a first working time length to the time length of a historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure values which are not greater than the pressure distribution reference value; then determining a target pressure range end value of the breathing machine according to the pressure distribution reference value; and setting the working pressure of the breathing machine in the target working period according to the end value of the target pressure range and the pressure distribution reference value. In the embodiment of the invention, the working pressure of the breathing machine in the target working period is automatically set by determining the end value of the target pressure range and the pressure distribution reference value without manual setting by a user and according to the end value of the target pressure range and the pressure distribution reference value, so that the pressure setting efficiency can be improved to a certain extent. Meanwhile, compared with the mode that only the pressure distribution reference value is determined, and the working pressure is directly set according to the preset fixed pressure range end value and the pressure distribution reference value, the pressure distribution reference value and the target pressure range end value of the breathing machine are determined simultaneously through the historical pressure value in the embodiment of the invention, so that the working pressure of the breathing machine is set according to the setting basis, the setting basis can be adapted to the current situation to a certain extent, the set working pressure can be more adapted to the user using the breathing machine at present, and the setting effect is further improved.
Drawings
FIG. 1 is a flow chart illustrating the steps of a method of pressure regulation for a ventilator of the present invention;
FIG. 2 is a flow chart illustrating the steps of another ventilator pressure regulation method of the present invention;
fig. 3 shows a block diagram of a pressure regulating device of a ventilator according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, a flowchart of steps of a method for adjusting pressure of a ventilator according to the present invention is shown, where the method may be directly applied to a ventilator for pressure control, or may be implemented by controlling a ventilator through an external device or software, and the embodiment of the present invention is not limited thereto. The method specifically comprises the following steps:
step 101, determining a pressure distribution reference value according to a historical pressure value in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value.
In the embodiment of the invention, the breathing machine can replace, control or change the normal physiological respiration of a person, increase the lung ventilation, improve the respiratory function, reduce the consumption of the respiratory function and save the heart reserve capacity. The historical effective operating period may refer to a period during which the ventilator is operating normally, i.e., normally assisting the user in breathing. The historical pressure values may be pressure values of the ventilator at various time points within a historical effective operating period, and in particular, the historical pressure values may be continuously changed with time. Because the breathing machine normally assists the user to breathe in the historical effective working period, the historical pressure value in the historical effective working period can be considered to be suitable for the user to a certain extent, namely, the historical pressure value has certain referential property and has guiding significance. Therefore, in the embodiment of the invention, the pressure distribution reference value can be determined by taking the historical pressure value in the historical effective working period as a basis.
The pressure distribution reference value can be used for representing a proper treatment pressure corresponding to the effective working period of the breathing machine, the pressure distribution reference value is one of historical pressure values, and in the effective working period of the historical pressure value, the value of the time ratio of the first working period corresponding to the historical pressure value which is less than or equal to the pressure distribution reference value in the effective working period of the historical working period is in a preset ratio range.
For example, the pressure distribution reference value may be represented as P95, that is, the historical pressure value of the ventilator during the historical effective operation period is 95% of the time that the historical pressure value of the ventilator is lower than P95, and of course, other preset ratios may be used to determine the pressure distribution reference value, which is not limited by the embodiment of the present invention.
And 102, determining a target pressure range end value of the breathing machine according to the pressure distribution reference value.
In this embodiment of the present invention, the target pressure range end may refer to upper and lower limits of the operating pressure of the ventilator, for example, the target pressure range end may be a maximum breathing pressure and a minimum breathing pressure, or may be a maximum inspiratory pressure and a minimum inspiratory pressure, and the specific type of the target pressure range is not limited in this embodiment of the present invention.
Specifically, after a user uses a ventilator to assist in breathing for a period of time, the physiological condition and the breathing function of the user may change, and accordingly, the range of the working pressure of the ventilator that the user can currently bear may also change. In one implementation, the ventilator is operated, and the pressure is selected as the working pressure from the preset fixed pressure range end value according to the preset fixed pressure distribution reference value. Therefore, if the pressure value not suitable for the user is included in the end value of the pressure range, the user is adversely affected.
For example, in one implementation, the selection is from a minimum pressure, and if the minimum pressure that the user can withstand is greater than the minimum pressure at the end of the pressure range, the ventilator may need to go through a period of time before being adjusted to the working pressure of the user, and during the period of pressure rise, the user may experience a large number of respiratory events, which may adversely affect the user. For example, when the pressure of the ventilator is not appropriate, residual respiratory events may frequently occur during the use of the ventilator by the user, and further the sleep of the user may be seriously affected. Where respiratory events may be apnea and hypopnea, hypopnea refers to a reduction in respiratory airflow by more than 50% of the airflow, accompanied by a reduction in blood oxygen saturation of more than 4%.
Compared with the method that the preset fixed pressure range end value is directly used, the method and the device provided by the embodiment of the invention further determine the target pressure range end value more suitable for the user again through the pressure distribution reference value, and further ensure that the working pressure set according to the target pressure range end value, namely the pressure distribution reference value, is more suitable for the user to a certain extent.
And 103, setting the working pressure of the breathing machine in a target working period according to the target pressure range end value and the pressure distribution reference value.
In the embodiment of the present invention, the target working period may refer to a current working period of the ventilator or a next working period of the ventilator. Because the target pressure range end value and the pressure distribution reference value are determined according to the historical pressure value in the historical effective working period with referential property and guiding significance, the target pressure range end value and the pressure distribution reference value can be considered to be suitable for the physical state of the current user on a certain course, and therefore the working pressure can be set according to the target pressure range end value and the pressure distribution reference value, the working pressure can be ensured to be more suitable for the physical state of the user, and the setting effect of the working pressure is further improved.
In summary, in the pressure adjustment method for the breathing machine provided by the embodiment of the present invention, a pressure distribution reference value is determined according to a historical pressure value in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to historical pressure values, the ratio of a first working time length to the time length of a historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure values which are not greater than the pressure distribution reference value; then determining a target pressure range end value of the breathing machine according to the pressure distribution reference value; and setting the working pressure of the breathing machine in the target working period according to the end value of the target pressure range and the pressure distribution reference value. In the embodiment of the invention, the working pressure of the breathing machine in the target working period is automatically set by determining the end value of the target pressure range and the pressure distribution reference value without manual setting by a user and according to the end value of the target pressure range and the pressure distribution reference value, so that the pressure setting efficiency can be improved to a certain extent. Meanwhile, compared with the mode that only the pressure distribution reference value is determined, and the working pressure is directly set according to the preset fixed pressure range end value and the pressure distribution reference value, the pressure distribution reference value and the target pressure range end value of the breathing machine are determined simultaneously through the historical pressure value in the embodiment of the invention, so that the working pressure of the breathing machine is set according to the setting basis, the setting basis can be adapted to the current situation to a certain extent, the set working pressure can be more adapted to the user using the breathing machine at present, and the setting effect is further improved.
Referring to fig. 2, a flowchart of steps of another method for adjusting pressure of a ventilator according to the present invention is shown, where the method may be directly applied to a ventilator for pressure adjustment, or may be implemented by controlling a ventilator through an external device or software, and the embodiment of the present invention is not limited thereto. The method specifically comprises the following steps:
step 201, determining a pressure distribution reference value according to a historical pressure value in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value.
Optionally, the historical effective working period may be a working period in which the continuous working time of the ventilator is longer than a preset time, and the proportion of a second working time of the ventilator in the continuous working time is greater than a preset proportion threshold; and the air leakage of the breathing machine in the second working period is not greater than a preset air leakage threshold value.
In the embodiment of the present invention, the preset duration may refer to a duration threshold set according to an actual requirement, for example, the preset duration may be set to 4 hours, and correspondingly, the duration of the continuous operation of the ventilator is greater than 4 hours, which may be used as one of the determination conditions of the historical effective operation period.
The preset air leakage threshold may refer to a preset threshold of ventilator air leakage, and may be, for example, 90 Liters Per Minute (LPM). The preset air leakage threshold value can be used for representing the working state of the breathing machine, and if the air leakage is too large and exceeds the preset air leakage threshold value, the breathing machine can be judged to be in an invalid working state within the time corresponding to the overlarge air leakage. The second operation duration may refer to a time when the air leakage of the ventilator is not greater than a preset threshold, for example, "the second operation duration with the air leakage less than 90LPM is greater than 95% of the continuous operation duration" may be used as the second determination condition of the valid operation period. When the two judgment conditions are met, the working period can be considered as a history effective working period.
In the embodiment of the invention, the working time interval meeting the two judgment conditions is taken as the historical effective working time interval, so that the historical pressure value in the historical effective working time interval can be ensured to accurately provide reference, and the accuracy of the pressure distribution reference value and the target pressure range end value determined according to the historical pressure value in the historical effective working time interval can be further ensured to a certain extent.
Optionally, the pressure distribution reference value may include a first distribution reference value and a second distribution reference value; the number of the historical effective working periods is not less than a preset number threshold.
In the embodiment of the present invention, during calculation of the pressure distribution reference value, the proportion of the duration of the sum of the operating durations corresponding to the historical pressure values not greater than the pressure distribution reference value in the historical effective operating period may be different values, for example, P95, or P50, where the proportion of the duration of the historical pressure value of the operation of the ventilator being lower than P95 is 95%, or the proportion of the duration of the historical pressure value of the operation of the ventilator being lower than P50 is 50%. Accordingly, the first distribution reference value may be P95 and the second distribution reference value may be P50.
In this embodiment of the present invention, the preset number threshold may be the number of preset historical effective operating periods, for example, may be 2, 3, 4, 5, and the like, and for example, the pressure distribution reference value may be calculated based on data in 5 historical effective operating periods. It should be noted that, when the number acquired by the ventilator does not satisfy the preset number threshold, the working pressure may be set by using a default pressure value of the ventilator, and the step is executed according to the historical effective working time period when at least the preset number threshold number of historical effective working time periods can be acquired. In the embodiment of the invention, the pressure distribution reference value and the target pressure range end value are determined according to the historical pressure values in the historical effective working time period under the condition that a plurality of historical effective working time period data are obtained, namely, the historical effective working time period data have enough data to be referred to, so that the accuracy of the determined pressure distribution reference value and the determined target pressure range end value can be ensured, and the accuracy of the pressure setting of the breathing machine in the subsequent step is further improved.
Correspondingly, the step 201 can be specifically realized through the following substeps 2011 to 2012:
sub-step 2011: and for any historical effective working period, calculating a first distribution sub-reference value and a second distribution sub-reference value corresponding to the historical effective working period according to the historical pressure values in the historical effective working period.
In this embodiment of the present invention, the first distribution sub-reference value may represent a first pressure distribution reference value determined to be adapted to the target working period according to the historical pressure values in the historical effective working period, and the second distribution sub-reference value may represent a second pressure distribution reference value determined to be adapted to the target working period according to the historical pressure values in the historical effective working period.
Optionally, this sub-step 2011 may be implemented by the following steps (1) to (2):
step (1): and sequentially selecting m historical pressure values and n historical pressure values from the minimum historical pressure value according to the size of the pressure value.
In the embodiment of the invention, when a first distribution sub-reference value and a second distribution sub-reference value in a historical effective working period are calculated, working time corresponding to each historical pressure value can be determined, then the working time is sorted according to the historical pressure values from small to large, the historical pressure value with the ratio of the sum of m corresponding working time to the time of the historical effective working period equal to a first preset ratio is selected to determine the first distribution sub-reference value, and the historical pressure value with the ratio of the sum of n corresponding working time to the time of the historical effective working period equal to a second preset ratio is selected to determine the first distribution sub-reference value. Wherein m and n are integers larger than 0, and the working time lengths corresponding to each historical pressure value are different, so that the specific number of m and n is not fixed.
Step (2): taking a maximum historical pressure value of the m historical pressure values as the first distribution sub-reference value, and taking a maximum historical pressure value of the n historical pressure values as the second distribution sub-reference value. The ratio of the sum of the corresponding working durations of the m historical pressure values to the duration of the historical effective working period is equal to a first preset ratio, and the ratio of the sum of the corresponding working durations of the n historical pressure values to the duration of the historical effective working period is equal to a second preset ratio; the first preset ratio and the second preset ratio are within the preset ratio range.
In this embodiment of the present invention, the first preset ratio and the second preset ratio may be used to represent a ratio between a sum of operating durations corresponding to a plurality of historical pressure values and a duration of a historical effective operating period, and may be specifically 50% or 90% or 95%.
For example, when the ratio of the sum of the corresponding operating durations of the m historical pressure values to the duration of the historical effective operating period is equal to 95%, the largest historical pressure value of the m historical pressure values may be taken as P95; when the ratio of the sum of the corresponding operating time periods of the n historical pressure values to the time period of the historical effective operating period is equal to 50%, the largest historical pressure value of the n historical pressure values may be taken as P50.
Substep 2012: determining the average value of the first distribution sub-reference value and the average value of the second distribution sub-reference value as the first distribution reference value and the second distribution reference value respectively; wherein the first distribution reference value is greater than the second distribution reference value.
In the embodiment of the present invention, each historical effective working period corresponds to a group of first distribution sub-reference values and second distribution sub-reference values, in this step, an average value of the first distribution sub-reference values may be calculated according to all the first distribution sub-reference values to obtain first distribution reference values, and an average value of the second distribution sub-reference values may be calculated according to all the second distribution sub-reference values to obtain second distribution reference values.
In the embodiment of the invention, the first distribution sub-reference value and the second distribution sub-reference value corresponding to each historical effective working period are calculated according to the historical pressure values in the historical effective working period, and then the average value of the first distribution sub-reference value and the average value of the second distribution sub-reference value are determined as the first distribution reference value and the second distribution reference value respectively, so that the pressure data in a plurality of historical effective working periods can be integrated, the obtained pressure distribution reference values are more consistent with the actual breathing state of a user, and a respirator working according to the working pressure set by the pressure distribution reference values can be used for assisting the breathing of the user more effectively.
And step 202, determining a target pressure range end value of the breathing machine according to the pressure distribution reference value.
Optionally, the step 202 may be specifically implemented by the following implementation mode one and implementation mode two.
The first implementation mode,
Optionally, the end value of the target pressure range includes a minimum respiratory pressure end value and a maximum respiratory pressure end value.
In the embodiment of the invention, the first implementation mode can be suitable for a single-level respirator. The single level ventilator may refer to a ventilator in which the inspiratory pressure and the expiratory pressure applied to the user are the same when the user inhales and exhales. The single-level respirator in the embodiment of the invention mainly refers to an automatic CPAP (automatic continuous Positive Airway pressure) respirator, namely a full-automatic continuous Positive Airway pressure respirator, and the respirator can automatically adjust the treatment pressure within a set pressure range according to the Airway obstruction condition of a user.
In an embodiment of the present invention, the target pressure range end value of the AutoCPAP ventilator may include a minimum respiratory pressure end value and a maximum respiratory pressure end value, that is, when the ventilator is in operation, the working pressure fluctuates within a range of the minimum respiratory pressure end value and the maximum respiratory pressure end value.
Accordingly, this step 202 can be realized by the following substeps (3) to (4).
And (3) calculating the minimum respiratory pressure end value according to the second distribution reference value and a first preset constant.
In an embodiment of the present invention, the minimum respiratory pressure endpoint may refer to the minimum respiratory pressure of the AutoCPAP ventilator, i.e., the minimum value of the inspiratory pressure applied to the user and the minimum value of the expiratory pressure applied to the user. The first preset constant may be a constant preset by a user, and the user may set the constant based on actual needs, such as 2, 3, 4, and the like. Specifically, the minimum respiratory pressure end value may be calculated by the second distribution reference value and the first preset constant, for example, the second distribution reference value may be P50, and the minimum respiratory pressure end value may be the sum or the difference between P50 and the first preset constant, which is not limited by the embodiment of the present invention.
And (4) calculating the maximum respiratory pressure end value according to the first distribution reference value and a second preset constant.
In an embodiment of the present invention, the maximum respiratory pressure endpoint may refer to the maximum respiratory pressure of the AutoCPAP ventilator, i.e., the maximum value of the inspiratory pressure applied to the user and the maximum value of the expiratory pressure applied to the user. The second preset constant may be a constant preset by a user, and the user may set the second preset constant based on actual needs, such as 2, 3, 4, 5, and the like. Specifically, the maximum respiratory pressure end value may be calculated by a first distribution reference value and a second preset constant, for example, the first distribution reference value may be P95, and the minimum respiratory pressure end value may be the sum of P95 and the second preset constant, which is not limited by the embodiment of the present invention.
Specifically, the substep (4) can be realized by the following steps (a) to (c):
and (a) summing the first distribution reference value and the second preset constant to obtain a first sum value.
In the embodiment of the invention, the first distribution reference value and the second preset constant are added to obtain the first sum.
And (b) if the first sum is not greater than a preset end value threshold, taking the first sum as the maximum respiratory pressure end value.
In the embodiment of the present invention, the preset endpoint threshold may be the highest pressure that the ventilator is allowed to apply, which is set according to actual conditions.
When the first sum is not greater than the preset end threshold, the calculated first sum may be considered to be within a reasonable range, and thus, the first sum may be taken as the maximum respiratory pressure end. The preset threshold may be 20 (hpa, kpa).
And (c) if the first sum is larger than a preset end value threshold, taking the preset end value threshold as the maximum respiratory pressure end value.
When the first sum is greater than the preset end value threshold, the calculated first sum is considered to be beyond the reasonable range, and the reference value is low. Therefore, the preset endpoint threshold can be directly taken as the maximum respiratory pressure endpoint.
In the embodiment of the invention, the first sum is used as the maximum respiratory pressure end value when the first sum is larger than the preset end value threshold. And taking the first sum as the maximum respiratory pressure end value when the calculated first sum is not greater than the preset end value threshold value. Can ensure the rationality of maximum respiratory pressure end value to a certain extent, and then avoid the problem that the subsequent unreasonable operating pressure that sets up leads to the user to receive the injury.
In the embodiment of the invention, for a single horizontal respirator, the minimum respiratory pressure end value is obtained by calculating the second distribution reference value and the first preset constant, and the maximum respiratory pressure end value is obtained by calculating the first distribution reference value and the second preset constant, so that the target pressure range end value can be calculated based on historical pressure data of a plurality of historical effective working periods of the respirator, the intelligent regulation of the pressure end value of the respirator is realized, meanwhile, the target pressure range end value can be ensured to be adaptive to the body state of a user in the target working period, and the problem of negative influence on the user in the pressure regulation process of the respirator is further avoided.
The second implementation mode,
Optionally, the target pressure range end values may include a minimum expiratory pressure end value, a minimum inspiratory pressure end value, and a maximum inspiratory pressure end value.
In the embodiment of the invention, the second implementation mode can be suitable for a bi-level respirator. The bi-level ventilator may be a bi-level positive airway pressure ventilator (BPAP) that can set and adjust an inspiratory pressure (IPAP) and an expiratory pressure (EPAP), i.e., the bi-level ventilator applies different inspiratory and expiratory pressures to a user when the user inhales and exhales. For example, the ventilator may provide a higher inspiratory pressure to keep the airway open when the user is inhaling and a lower expiratory pressure when the user is exhaling to ensure the user breathes smoothly.
In the embodiment of the present invention, when the ventilator is a bi-level ventilator, the end value of the target pressure range includes a minimum expiratory pressure end value, a minimum inspiratory pressure end value, and a maximum inspiratory pressure end value, and the maximum expiratory pressure end value may be calculated based on the three end values, which is not specifically limited in this embodiment of the present invention.
Accordingly, this step 202 can be realized by the following substeps (5) to (7):
and (5) calculating the minimum expiratory pressure end value according to the second distribution reference value and a third preset constant.
In the embodiment of the present invention, the minimum expiratory pressure end value may refer to the minimum expiratory pressure of a bi-level ventilator. The third preset constant may be a constant preset by a user, and the user may set the third preset constant based on actual needs, such as 2, 3, 4, 5, and the like. Specifically, the minimum expiratory pressure end value may be calculated from the second distribution reference value and a third preset constant, for example, the second distribution reference value may be P50, and the minimum expiratory pressure end value may be a sum or a difference between P50 and the third preset constant, which is not limited in this embodiment of the present invention.
And (6) calculating the minimum inhalation pressure end value according to the minimum exhalation pressure end value and a fourth preset constant.
In an embodiment of the present invention, the maximum inspiratory pressure end value may refer to a minimum inspiratory pressure of a bi-level ventilator. The fourth preset constant may be referred to as Pressure Support (PS), which may be set by the user based on actual conditions to ensure sufficient Tidal volume (VT, volume per inhalation or exhalation during quiet breathing). The fourth predetermined constant, i.e., the pressure support, can be typically 4 to 8 hpa. Specifically, the maximum inspiratory pressure end may be calculated by the minimum expiratory pressure end and a fourth preset constant, for example, the maximum inspiratory pressure end may be a sum of the minimum expiratory pressure end and the fourth preset constant, and the specific calculation manner is not limited in the embodiment of the present invention.
And (7) calculating the maximum suction pressure end value according to the first distribution reference value, a fifth preset constant and the fourth preset constant.
In the embodiment of the present invention, the maximum inspiratory pressure end value may refer to the maximum inspiratory pressure of a bi-level ventilator. The fifth preset constant may be a constant preset by a user, and the user may set the fifth preset constant based on actual needs, such as 2, 3, 4, 5, and the like. Specifically, in this step, the sum of the first distribution reference value, the fifth preset constant and the fourth preset constant may be used as the maximum suction pressure end value, where the first distribution reference value may be P95.
Specifically, the substep (7) can be realized by the following steps (d) to (f):
and (d) summing the first distribution reference value, the fifth preset constant and the fourth preset constant to obtain a second sum value.
In the embodiment of the invention, a second sum value can be obtained by summing the first distribution reference value, the fifth preset constant and the fourth preset constant PS, and subsequent judgment is carried out by using the second sum value to determine the maximum suction pressure end value.
And (e) if the second sum is not greater than a preset end value threshold, taking the second sum as the maximum suction pressure end value.
In the embodiment of the present invention, the preset endpoint threshold may be the highest pressure that the ventilator is allowed to apply, which is set according to actual conditions. When the second sum is not greater than the preset end threshold, the calculated second sum may be considered to be within a reasonable range, and thus, the second sum may be taken as the maximum suction pressure end. The preset threshold may be 20 (hpa, kpa).
And (f) if the second sum is larger than a preset end value threshold, taking the preset end value threshold as the maximum suction pressure end value.
When the second sum is greater than the preset end value threshold, the calculated second sum is considered to be beyond the reasonable range, and the reference value is low. Therefore, the preset threshold value can be directly used as the maximum suction pressure end value.
In the embodiment of the invention, the second sum is used as the maximum suction pressure end value when the second sum is larger than the preset end value threshold. And taking the second sum as the maximum suction pressure end value when the calculated second sum is not greater than the preset end value threshold value. Can ensure the rationality of the maximum inspiratory pressure end value to a certain extent, and further avoid the problem that the user is injured due to the unreasonable working pressure set subsequently.
In the embodiment of the invention, for a bi-level respirator, the minimum expiratory pressure end value is obtained through calculation of the second distribution reference value and the third preset constant, the maximum inspiratory pressure end value is obtained through calculation of the minimum expiratory pressure end value and the fourth preset constant, and the maximum inspiratory pressure end value is obtained through calculation of the first distribution reference value, the fifth preset constant and the fourth preset constant. Therefore, the target pressure range end value can be calculated based on historical pressure data of a plurality of effective working periods of the breathing machine, intelligent adjustment of the breathing machine pressure end value is achieved, meanwhile, the target pressure range end value can be ensured to be adaptive to the body state of a user in the target working period, the problem of negative influence on the user in the breathing machine pressure adjusting process is avoided, and the breathing assistance effect of the breathing machine is improved.
Step 203, selecting the working pressure from a target pressure range corresponding to the end value of the target pressure range according to the pressure distribution reference value; wherein the pressure distribution reference value is the first distribution reference value; and the ratio of the sum of the working time lengths corresponding to the working pressures smaller than the pressure distribution reference value in the target working time period to the time length of the target working time period is equal to a first preset ratio.
In the embodiment of the present invention, the pressure distribution reference value may be a first distribution reference value, and may be P95, for example. Specifically, when the working pressure of the breathing machine is set according to the end value of the target pressure range and the pressure distribution reference value, the pressure range of the breathing machine may be set according to the end value of the target pressure range, and then the working pressure of the breathing machine is set according to the first distribution reference value, that is, P95 in the target working period may be set as the first distribution reference value, so that the working pressure in the target working period is in the target pressure range, and meanwhile, the ratio of the sum of the working time lengths corresponding to the working pressures lower than the first distribution reference value to the target working period is 95%.
In the embodiment of the invention, the working pressure is selected from the target pressure range corresponding to the end value of the target pressure range according to the pressure distribution reference value, namely the working pressure in the target working time period is set based on the average value of P95 in a plurality of effective working time periods, so that the intelligent regulation of the pressure of the breathing machine can be realized, the frequent manual regulation is correspondingly reduced, and the regulation efficiency of the breathing machine is improved.
Optionally, after the working pressure is set, the following steps (8) to (10) may be further performed:
and (8) acquiring the respiratory disturbance index in the at least one historical effective working period and the current working pressure of the breathing machine.
In the embodiment of the invention, the breathing disorder index and the current working pressure value can be obtained for subsequent pressure adjustment. The respiratory disturbance index (AHI or RDI) may refer to the average number of apneas and hypopneas per hour, wherein an expiratory apnea may refer to a complete cessation of oronasal airflow for 10 seconds or more.
Step (9), determining the pressure adjustment amount of the breathing machine according to the preset corresponding relation corresponding to the current working pressure; the preset corresponding relation represents the corresponding relation between the respiratory disturbance index and the pressure adjustment amount under the current working pressure.
In the embodiment of the invention, the corresponding relation between the respiratory disturbance index and the pressure adjustment quantity is preset in the breathing machine, and the current working pressure of the breathing machine is different, and the corresponding relation between the respiratory disturbance index and the pressure adjustment quantity is different. Specifically, in this step, the corresponding relationship under the current working pressure can be determined by the obtained current working pressure of the ventilator, and then the value of the pressure adjustment amount is determined according to the value of the respiratory disturbance index.
Optionally, step (9) may be implemented by the following substeps (g) to (h):
and (g) obtaining the snoring frequency within the at least one historical effective working period if the respiratory disturbance index is less than a preset respiratory disturbance index threshold.
In the embodiment of the present invention, the preset respiratory disturbance index threshold may be a normal threshold of the respiratory disturbance index, for example, 5, that is, when the respiratory disturbance index is smaller than the preset respiratory disturbance index threshold, it indicates that the respiratory disturbance index of the user is normal. The snoring frequency may refer to the number of snoring sounds per hour (Snore Index, SNI).
In the embodiment of the invention, under the condition that the respiratory disturbance index is smaller than the preset respiratory disturbance index threshold value, namely under the condition that the respiratory disturbance index of a user is normal, whether the working pressure of the breathing machine needs to be adjusted cannot be accurately judged only according to the index of the respiratory disturbance index. According to the embodiment of the invention, the snoring frequency in at least one historical effective working period is obtained, the pressure adjustment amount can be comprehensively judged through a plurality of parameters, and the adjustment accuracy and sensitivity are improved.
And (h) determining the pressure adjustment amount from the preset corresponding relation according to the respiratory disturbance index and the snoring frequency.
In the embodiment of the invention, under different working pressures of the breathing machine, two parameters of the breathing disorder index and the snoring frequency can correspond to a pressure adjustment amount in a preset corresponding relation.
For example, the relationship between the breathing disorder index AHI, the snoring frequency SNI and the pressure adjustment amount of the ventilator under different working pressures can be shown in the following table:
Figure BDA0002529656300000151
as shown in the above table, when the current working pressure P of the ventilator is less than or equal to 6, the respiratory disturbance index AHI is less than 5, and the snoring frequency SNI is greater than or equal to 4, the pressure adjustment amount of the ventilator at this time is +0.5hpa, i.e., the adjustment amount is adjusted up to 0.5 hpa. Of course, the user may set other corresponding relationships according to actual requirements, which is not limited in the embodiment of the present invention.
And (10) adjusting the current pressure of the breathing machine according to the pressure adjustment amount.
In the embodiment of the invention, the currently suitable pressure adjustment amount is determined through the respiratory disturbance index, the snoring frequency and the current working pressure value of the breathing machine, and the current pressure value of the breathing machine is adjusted according to the pressure adjustment amount, so that the working pressure of the breathing machine can be adaptively adjusted according to the actual breathing condition of a user, and the problem that the set working pressure is not accurate enough to cause negative influence on the user is further avoided to a certain extent. Meanwhile, the current working pressure is adjusted through automatic adaptability, manual frequent adjustment can be avoided, and labor cost is saved.
It should be noted that the Pressure adjustment manner shown in the above steps (8) to (10) may also be applied to a Continuous Positive Airway Pressure (CPAP). A CPAP ventilator may be a ventilator that provides a relatively stable positive airway pressure. In spontaneous breathing conditions where the user has a steady respiratory drive and an appropriate tidal volume, CPAP ventilators are required to provide a relatively steady positive airway pressure to the user, for example, to assist the user's breathing by applying a degree of positive intra-airway pressure in the form of continuous positive airway pressure. CPAP ventilators therefore generally need to provide a constant positive airway pressure to ensure stable airflow. However, in practical application scenarios, the required positive airway pressure may be different as the physical state of the user changes, and therefore, the working pressure may need to be adjusted at times. According to the pressure adjusting mode provided by the embodiment of the application, the pressure adjusting quantity is determined firstly according to the breathing disorder index and the snoring frequency which can reflect the body state of the user, and the adjustment is carried out according to the pressure adjusting quantity. And then can be so that to a certain extent carry out accurate stable adjustment to operating pressure, when realizing the adjustment, ensure that the user can adapt to the atmospheric pressure and change, and then ensure the adjustment effect.
In summary, in the pressure adjustment method for the breathing machine provided by the embodiment of the present invention, a pressure distribution reference value is determined according to a historical pressure value in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to historical pressure values, the ratio of a first working time length to the time length of a historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure values which are not greater than the pressure distribution reference value; then determining a target pressure range end value of the breathing machine according to the pressure distribution reference value; when the pressure distribution reference value is the first distribution reference value, selecting working pressure from a target pressure range corresponding to the end value of the target pressure range according to the pressure distribution reference value; and the ratio of the sum of the working time lengths corresponding to the working pressures smaller than the pressure distribution reference value in the target working time period to the time length of the target working time period is equal to a first preset ratio. In the embodiment of the invention, the working pressure of the breathing machine in the target working period is automatically set by determining the end value of the target pressure range and the pressure distribution reference value without manual setting by a user and according to the end value of the target pressure range and the pressure distribution reference value, so that the pressure setting efficiency can be improved to a certain extent. Meanwhile, compared with the mode that only the pressure distribution reference value is determined, and the working pressure is directly set according to the preset fixed pressure range end value and the pressure distribution reference value, the pressure distribution reference value and the target pressure range end value of the breathing machine are determined simultaneously through the historical pressure value in the embodiment of the invention, so that the working pressure of the breathing machine is set according to the setting basis, the setting basis can be adapted to the current situation to a certain extent, the set working pressure can be more adapted to the user using the breathing machine at present, and the setting effect is further improved.
It should be noted that, for simplicity of description, the method embodiments are described as a series of acts or combination of acts, but those skilled in the art will recognize that the present invention is not limited by the illustrated order of acts, as some steps may occur in other orders or concurrently in accordance with the embodiments of the present invention. Further, those skilled in the art will appreciate that the embodiments described in the specification are presently preferred and that no particular act is required to implement the invention.
Referring to fig. 3, a block diagram of a ventilator pressure regulating device of the present invention is shown, and the device 30 may include the following modules:
a first determining module 301, configured to determine a pressure distribution reference value according to a historical pressure value in at least one historical effective operating period of the ventilator; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value.
A second determining module 302, configured to determine a target pressure range end value of the ventilator according to the pressure distribution reference value.
A setting module 303, configured to set a working pressure of the ventilator within a target working period according to the target pressure range end value and the pressure distribution reference value.
Optionally, the historical effective working period is a working period in which the continuous working time of the breathing machine is longer than a preset time, and the proportion of a second working time of the breathing machine in the continuous working time is greater than a preset proportion threshold; and the air leakage of the breathing machine in the second working period is not greater than a preset air leakage threshold value.
Optionally, the pressure distribution reference value includes a first distribution reference value and a second distribution reference value, and the number of the historical effective working periods is not less than a preset number threshold: the second determining module 302 is specifically configured to:
for any historical effective working period, calculating a first distribution sub-reference value and a second distribution sub-reference value corresponding to the historical effective working period according to historical pressure values in the historical effective working period; determining the average value of the first distribution sub-reference value and the average value of the second distribution sub-reference value as the first distribution reference value and the second distribution reference value respectively; the first distribution reference value is greater than the second distribution reference value.
Optionally, the first determining module 301 is specifically configured to:
sequentially selecting m historical pressure values and n historical pressure values from the minimum historical pressure value according to the size of the pressure value; taking a maximum historical pressure value of the m historical pressure values as the first distribution sub-reference value, and taking a maximum historical pressure value of the n historical pressure values as the second distribution sub-reference value; the ratio of the sum of the corresponding working durations of the m historical pressure values to the duration of the historical effective working period is equal to a first preset ratio, and the ratio of the sum of the corresponding working durations of the n historical pressure values to the duration of the historical effective working period is equal to a second preset ratio; the first preset ratio and the second preset ratio are within the preset ratio range.
Optionally, the end value of the target pressure range includes a minimum respiratory pressure end value and a maximum respiratory pressure end value; the second determining module 302 includes:
the first calculation submodule is used for calculating the minimum respiratory pressure end value according to the second distribution reference value and a first preset constant; the second calculation submodule is used for calculating the maximum respiratory pressure end value according to the first distribution reference value and a second preset constant; the second calculation submodule is specifically configured to:
summing the first distribution reference value and the second preset constant to obtain a first sum value; if the first sum is not larger than a preset end value threshold, taking the first sum as the maximum respiratory pressure end value; and if the first sum is larger than a preset end value threshold, taking the preset end value threshold as the maximum respiratory pressure end value.
Optionally, the target pressure range end values include a minimum expiratory pressure end value, a minimum inspiratory pressure end value, and a maximum inspiratory pressure end value; the second determining module 302 includes:
the third calculation submodule is used for calculating the minimum expiratory pressure end value according to the second distribution reference value and a third preset constant; the fourth calculation submodule is used for calculating the minimum inhalation pressure end value according to the minimum exhalation pressure end value and a fourth preset constant; and the fifth calculation submodule is used for calculating the maximum suction pressure end value according to the first distribution reference value, a fifth preset constant and the fourth preset constant.
Optionally, the pressure distribution reference value is the first distribution reference value; the setting module 303 is specifically configured to: selecting the working pressure from a target pressure range corresponding to the end value of the target pressure range according to the pressure distribution reference value; and the ratio of the sum of the working time lengths corresponding to the working pressures smaller than the pressure distribution reference value in the target working time period to the time length of the target working time period is equal to a first preset ratio.
Optionally, the apparatus 30 further includes:
the acquisition module is used for acquiring the respiratory disturbance index in the at least one historical effective working period and the current working pressure of the breathing machine; the third determining module is used for determining the pressure adjustment quantity of the breathing machine according to the preset corresponding relation corresponding to the current working pressure; the preset corresponding relation represents the corresponding relation between the respiratory disturbance index and the pressure adjustment amount under the current working pressure; and the adjusting module is used for adjusting the current pressure of the breathing machine according to the pressure adjusting quantity.
Optionally, the third determining module is specifically configured to:
acquiring the snoring frequency within the at least one historical effective working period under the condition that the respiratory disturbance index is smaller than a preset respiratory disturbance index threshold value; and determining the pressure adjustment amount from the preset corresponding relation according to the respiratory disturbance index and the snoring frequency.
In summary, in the pressure adjustment device for a ventilator provided in the embodiment of the present invention, a pressure distribution reference value is determined according to a historical pressure value in at least one historical effective working period of the ventilator; the pressure distribution reference value belongs to historical pressure values, the ratio of a first working time length to the time length of a historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure values which are not greater than the pressure distribution reference value; then determining a target pressure range end value of the breathing machine according to the pressure distribution reference value; and setting the working pressure of the breathing machine in the target working period according to the end value of the target pressure range and the pressure distribution reference value. In the embodiment of the invention, the working pressure of the breathing machine in the target working period is automatically set by determining the end value of the target pressure range and the pressure distribution reference value without manual setting by a user and according to the end value of the target pressure range and the pressure distribution reference value, so that the pressure setting efficiency can be improved to a certain extent. Meanwhile, compared with the mode that only the pressure distribution reference value is determined, and the working pressure is directly set according to the preset fixed pressure range end value and the pressure distribution reference value, the pressure distribution reference value and the target pressure range end value of the breathing machine are determined simultaneously through the historical pressure value in the embodiment of the invention, so that the working pressure of the breathing machine is set according to the setting basis, the setting basis can be adapted to the current situation to a certain extent, the set working pressure can be more adapted to the user using the breathing machine at present, and the setting effect is further improved.
Optionally, an embodiment of the present invention further provides a ventilator, where the ventilator includes a processor, a memory, and a computer program that is stored in the memory and is executable on the processor, and when the computer program is executed by the processor, the computer program implements each process of the pressure adjustment method embodiment of the ventilator, and can achieve the same technical effect, and is not described herein again to avoid repetition.
Optionally, an embodiment of the present invention further provides a computer-readable storage medium, where a computer program is stored on the computer-readable storage medium, and when the computer program is executed by a processor, the computer program implements each process of the above-mentioned method for adjusting pressure of a ventilator, and can achieve the same technical effect, and in order to avoid repetition, the details are not repeated here.
The embodiments in the present specification are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
As is readily imaginable to the person skilled in the art: any combination of the above embodiments is possible, and thus any combination between the above embodiments is an embodiment of the present invention, but the present disclosure is not necessarily detailed herein for reasons of space.
In the description provided herein, numerous specific details are set forth. It is understood, however, that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.
Similarly, it should be appreciated that in the foregoing description of exemplary embodiments of the invention, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the invention and aiding in the understanding of one or more of the various inventive aspects. However, the disclosed method should not be interpreted as reflecting an intention that: that the invention as claimed requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive aspects lie in less than all features of a single foregoing disclosed embodiment. Thus, the claims following the detailed description are hereby expressly incorporated into this detailed description, with each claim standing on its own as a separate embodiment of this invention.
Those skilled in the art will appreciate that the modules in the device in an embodiment may be adaptively changed and disposed in one or more devices different from the embodiment. The modules or units or components of the embodiments may be combined into one module or unit or component, and furthermore they may be divided into a plurality of sub-modules or sub-units or sub-components. All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the processes or elements of any method or apparatus so disclosed, may be combined in any combination, except combinations where at least some of such features and/or processes or elements are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.
Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features included in other embodiments, rather than other features, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the claims, any of the claimed embodiments may be used in any combination.
It should be noted that the above-mentioned embodiments illustrate rather than limit the invention, and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word "comprising" does not exclude the presence of elements or steps not listed in a claim. The word "a" or "an" preceding an element does not exclude the presence of a plurality of such elements. The invention may be implemented by means of hardware comprising several distinct elements, and by means of a suitably programmed computer. In the unit claims enumerating several means, several of these means may be embodied by one and the same item of hardware. The usage of the words first, second and third, etcetera do not indicate any ordering. These words may be interpreted as names.

Claims (22)

1. A method of pressure regulation for a ventilator, the method comprising:
determining a pressure distribution reference value according to a historical pressure value in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value;
determining a target pressure range end value of the breathing machine according to the pressure distribution reference value;
and setting the working pressure of the breathing machine in a target working period according to the target pressure range end value and the pressure distribution reference value.
2. The method of claim 1, wherein the historical effective operating period is an operating period in which a duration of operation of the ventilator is greater than a preset duration and a proportion of a second operating period of the ventilator within the duration of operation is greater than a preset proportion threshold; and the air leakage of the breathing machine in the second working period is not greater than a preset air leakage threshold value.
3. The method according to claim 1, wherein the pressure distribution reference values comprise a first distribution reference value and a second distribution reference value, and the number of the historical effective working periods is not less than a preset number threshold;
the determining a pressure distribution reference value according to the historical pressure values in at least one historical effective working period of the ventilator comprises:
for any historical effective working period, calculating a first distribution sub-reference value and a second distribution sub-reference value corresponding to the historical effective working period according to historical pressure values in the historical effective working period;
determining the average value of the first distribution sub-reference value and the average value of the second distribution sub-reference value as the first distribution reference value and the second distribution reference value respectively;
wherein the first distribution reference value is greater than the second distribution reference value.
4. The method of claim 3, wherein calculating the first distributed sub-reference value and the second distributed sub-reference value corresponding to the historical valid operating period according to the historical pressure values in the historical valid operating period comprises:
sequentially selecting m historical pressure values and n historical pressure values from the minimum historical pressure value according to the size of the pressure value;
taking a maximum historical pressure value of the m historical pressure values as the first distribution sub-reference value, and taking a maximum historical pressure value of the n historical pressure values as the second distribution sub-reference value;
the ratio of the sum of the corresponding working durations of the m historical pressure values to the duration of the historical effective working period is equal to a first preset ratio, and the ratio of the sum of the corresponding working durations of the n historical pressure values to the duration of the historical effective working period is equal to a second preset ratio; the first preset ratio and the second preset ratio are within the preset ratio range.
5. The method of claim 3 or 4, wherein the target pressure range ends comprise a minimum respiratory pressure end and a maximum respiratory pressure end;
determining a target pressure range end value of the breathing machine according to the pressure distribution reference value, wherein the step of determining the target pressure range end value comprises the following steps:
calculating the minimum respiratory pressure end value according to the second distribution reference value and a first preset constant;
and calculating the maximum respiratory pressure end value according to the first distribution reference value and a second preset constant.
6. The method according to claim 5, wherein said calculating said maximum respiratory pressure end value according to said first distribution reference value and a second predetermined constant comprises:
summing the first distribution reference value and the second preset constant to obtain a first sum value;
if the first sum is not larger than a preset end value threshold, taking the first sum as the maximum respiratory pressure end value;
and if the first sum is larger than a preset end value threshold, taking the preset end value threshold as the maximum respiratory pressure end value.
7. The method of claim 3 or 4, wherein the target pressure range ends include a minimum end of exhalation pressure, a minimum end of inhalation pressure, and a maximum end of inhalation pressure;
determining a target pressure range end value of the breathing machine according to the pressure distribution reference value, wherein the step of determining the target pressure range end value comprises the following steps:
calculating the minimum expiratory pressure end value according to the second distribution reference value and a third preset constant;
calculating the minimum inhalation pressure end value according to the minimum exhalation pressure end value and a fourth preset constant;
and calculating the maximum suction pressure end value according to the first distribution reference value, a fifth preset constant and the fourth preset constant.
8. A method according to claim 3, characterized in that the pressure distribution reference value is the first distribution reference value;
the setting of the working pressure of the breathing machine in the target working period according to the end value of the target pressure range and the pressure distribution reference value comprises the following steps:
selecting the working pressure from a target pressure range corresponding to the end value of the target pressure range according to the pressure distribution reference value; and the ratio of the sum of the working time lengths corresponding to the working pressures smaller than the pressure distribution reference value in the target working time period to the time length of the target working time period is equal to a first preset ratio.
9. The method of claim 1, further comprising:
acquiring a respiratory disturbance index and the current working pressure of the breathing machine in the at least one historical effective working period;
determining the pressure adjustment amount of the breathing machine according to the preset corresponding relation corresponding to the current working pressure; the preset corresponding relation represents the corresponding relation between the respiratory disturbance index and the pressure adjustment amount under the current working pressure;
and adjusting the current pressure of the breathing machine according to the pressure adjustment amount.
10. The method of claim 9, wherein determining the pressure adjustment of the ventilator according to the preset corresponding relationship corresponding to the current working pressure value comprises:
acquiring the snoring frequency within the at least one historical effective working period under the condition that the respiratory disturbance index is smaller than a preset respiratory disturbance index threshold value;
and determining the pressure adjustment amount from the preset corresponding relation according to the respiratory disturbance index and the snoring frequency.
11. A pressure regulating device for a ventilator, the device comprising:
the first determination module is used for determining a pressure distribution reference value according to historical pressure values in at least one historical effective working period of the breathing machine; the pressure distribution reference value belongs to the historical pressure value, the ratio of a first working time length to the time length of the historical effective working time period is within a preset ratio range, and the first working time length is the sum of the working time lengths corresponding to the historical pressure value which is not greater than the pressure distribution reference value;
the second determination module is used for determining a target pressure range end value of the breathing machine according to the pressure distribution reference value;
and the setting module is used for setting the working pressure of the breathing machine in a target working period according to the target pressure range end value and the pressure distribution reference value.
12. The apparatus of claim 11, wherein the historical effective operating period is an operating period in which a duration of operation of the ventilator is greater than a preset duration and a duty cycle of a second operating period of the ventilator within the duration of operation is greater than a preset duty cycle threshold; and the air leakage of the breathing machine in the second working period is not greater than a preset air leakage threshold value.
13. The apparatus of claim 11, wherein the pressure distribution reference values comprise a first distribution reference value and a second distribution reference value, and the number of the historical active operating periods is not less than a preset number threshold;
the second determining module is specifically configured to:
for any historical effective working period, calculating a first distribution sub-reference value and a second distribution sub-reference value corresponding to the historical effective working period according to historical pressure values in the historical effective working period;
determining the average value of the first distribution sub-reference value and the average value of the second distribution sub-reference value as the first distribution reference value and the second distribution reference value respectively;
the first distribution reference value is greater than the second distribution reference value.
14. The apparatus of claim 13, wherein the first determining module is specifically configured to:
sequentially selecting m historical pressure values and n historical pressure values from the minimum historical pressure value according to the size of the pressure value;
taking a maximum historical pressure value of the m historical pressure values as the first distribution sub-reference value, and taking a maximum historical pressure value of the n historical pressure values as the second distribution sub-reference value;
the ratio of the sum of the corresponding working durations of the m historical pressure values to the duration of the historical effective working period is equal to a first preset ratio, and the ratio of the sum of the corresponding working durations of the n historical pressure values to the duration of the historical effective working period is equal to a second preset ratio; the first preset ratio and the second preset ratio are within the preset ratio range.
15. The device of claim 13 or 14, wherein the target pressure range ends comprise a minimum respiratory pressure end and a maximum respiratory pressure end;
the second determining module includes:
the first calculation submodule is used for calculating the minimum respiratory pressure end value according to the second distribution reference value and a first preset constant;
and the second calculation submodule is used for calculating the maximum respiratory pressure end value according to the first distribution reference value and a second preset constant.
16. The apparatus according to claim 15, wherein the second computation submodule is specifically configured to:
summing the first distribution reference value and the second preset constant to obtain a first sum value;
if the first sum is not larger than a preset end value threshold, taking the first sum as the maximum respiratory pressure end value;
and if the first sum is larger than a preset end value threshold, taking the preset end value threshold as the maximum respiratory pressure end value.
17. The apparatus of claim 13 or 14, wherein the target pressure range ends comprise a minimum end of exhalation pressure, a minimum end of inhalation pressure, and a maximum end of inhalation pressure;
the second determining module includes:
the third calculation submodule is used for calculating the minimum expiratory pressure end value according to the second distribution reference value and a third preset constant;
the fourth calculation submodule is used for calculating the minimum inhalation pressure end value according to the minimum exhalation pressure end value and a fourth preset constant;
and the fifth calculation submodule is used for calculating the maximum suction pressure end value according to the first distribution reference value, a fifth preset constant and the fourth preset constant.
18. The apparatus according to claim 13, wherein the pressure distribution reference value is the first distribution reference value;
the setting module is specifically configured to:
selecting the working pressure from a target pressure range corresponding to the end value of the target pressure range according to the pressure distribution reference value; and the ratio of the sum of the working time lengths corresponding to the working pressures smaller than the pressure distribution reference value in the target working time period to the time length of the target working time period is equal to a first preset ratio.
19. The apparatus of claim 11, further comprising:
the acquisition module is used for acquiring the respiratory disturbance index in the at least one historical effective working period and the current working pressure of the breathing machine;
the third determining module is used for determining the pressure adjustment quantity of the breathing machine according to the preset corresponding relation corresponding to the current working pressure; the preset corresponding relation represents the corresponding relation between the respiratory disturbance index and the pressure adjustment amount under the current working pressure;
and the adjusting module is used for adjusting the current pressure of the breathing machine according to the pressure adjusting quantity.
20. The apparatus of claim 19, wherein the third determining module is specifically configured to:
acquiring the snoring frequency within the at least one historical effective working period under the condition that the respiratory disturbance index is smaller than a preset respiratory disturbance index threshold value;
and determining the pressure adjustment amount from the preset corresponding relation according to the respiratory disturbance index and the snoring frequency.
21. A ventilator comprising a processor, a memory, and a computer program stored on the memory and executable on the processor, the computer program when executed by the processor implementing the steps of the method of pressure regulation of a ventilator according to any one of claims 1 to 10.
22. A computer-readable storage medium, on which a computer program is stored which, when being executed by a processor, carries out the steps of the method of pressure regulation of a ventilator according to any one of claims 1 to 10.
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