CN111643815A - Pulse generator and implantable sacral nerve stimulation system - Google Patents
Pulse generator and implantable sacral nerve stimulation system Download PDFInfo
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- CN111643815A CN111643815A CN202010505332.0A CN202010505332A CN111643815A CN 111643815 A CN111643815 A CN 111643815A CN 202010505332 A CN202010505332 A CN 202010505332A CN 111643815 A CN111643815 A CN 111643815A
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- 238000007789 sealing Methods 0.000 claims description 36
- 230000004936 stimulating effect Effects 0.000 claims description 24
- 230000000638 stimulation Effects 0.000 claims description 15
- 210000000078 claw Anatomy 0.000 claims description 12
- 210000005036 nerve Anatomy 0.000 claims description 8
- 239000004677 Nylon Substances 0.000 claims description 4
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 4
- 239000004433 Thermoplastic polyurethane Substances 0.000 claims description 4
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 claims description 4
- 229920001778 nylon Polymers 0.000 claims description 4
- 229920002530 polyetherether ketone Polymers 0.000 claims description 4
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 229920002379 silicone rubber Polymers 0.000 claims description 3
- 238000002513 implantation Methods 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 7
- 208000014674 injury Diseases 0.000 abstract description 5
- 230000008733 trauma Effects 0.000 abstract description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 239000010936 titanium Substances 0.000 description 8
- 229910052719 titanium Inorganic materials 0.000 description 8
- 238000010438 heat treatment Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 229920000249 biocompatible polymer Polymers 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
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- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 208000009722 Overactive Urinary Bladder Diseases 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000005674 electromagnetic induction Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/378—Electrical supply
- A61N1/3787—Electrical supply from an external energy source
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention provides a pulse generator and an implanted sacral nerve stimulation system, wherein the pulse generator comprises a top cover and a pulse generator main body, wherein an internal charging coil is arranged inside the top cover made of a biocompatible high polymer material and is directly or indirectly electrically connected with a rechargeable battery arranged inside the pulse generator; the pulse generator is creatively divided into two parts, and the internal charging coil is arranged inside the top cover made of a biocompatible high polymer material, so that the eddy heat effect caused by wireless charging can be avoided, and the charging efficiency is improved; the structure such as a shielding layer is not needed, the internal design is simplified, and the overall thickness is thinner; in addition, compared with the prior art, the thickness of the pulse generator main body is thinner, so that the battery can be designed to be thicker in the thickness direction, and the battery capacity is increased; or the thickness of the pulse generator body is slightly increased, so that the plane occupation is reduced, thereby reducing the surgical trauma during the implantation.
Description
Technical Field
The invention relates to an implantable medical device, in particular to a rechargeable implantable pulse generator and an implantable sacral nerve stimulation system.
Background
The sacral nerve stimulator, also known as a bladder pacemaker, can be used for treating symptoms of non-obstructive urinary retention and overactive bladder which are ineffective or intolerant to conservative treatment, is an implantable programmable device, generally comprises an internal implantation apparatus and an external control device, and exchanges information through bidirectional wireless communication.
In the prior art, an implantable medical device is generally powered by a battery, and sends stimulation pulses with specific frequency to stimulate a specific target spot for a long time, so that the symptoms of a patient are improved. Implantable medical devices are generally expensive, but have a short lifetime, and the main factor limiting the lifetime of implantable medical devices is battery capacity. In order to prolong the service life, some implantable medical devices are powered by lithium primary batteries with high energy density, such as lithium-chlorine sulfite batteries and lithium-polyfluorocarbon batteries. However, once the battery is exhausted, the patient has to be operated again to replace the implanted medical device, which not only causes physical trauma to the patient, but also causes great economic stress to the patient due to the expensive price.
In order to prolong the service life of implantable medical devices, people develop external rechargeable implantable medical devices. The external rechargeable implantable medical device generally comprises a metal titanium shell and a rechargeable battery encapsulated by the titanium shell, wherein in the process of external wireless charging, the shell and the rechargeable battery encapsulated by the titanium shell can generate eddy currents, and then heat is generated to increase the temperature of the battery and even the temperature of an implanted part of the whole implantable medical device. Excessive heating of the implanted components can have adverse effects on the human body, and the battery temperature increases, which can also affect the life of the battery itself.
Chinese patent document CN105268103A discloses an external rechargeable implanted medical instrument, which increases a heat shield layer between an internal charging energy receiving ring and a rechargeable battery inside the instrument in order to reduce excessive heating of the battery of the implanted component, however, the heat shield layer not only needs to realize electromagnetic shielding, but also needs to be electrically and thermally conductive, and has high requirements for installation positions, thereby resulting in high production cost, high precision requirements and high production difficulty.
Chinese patent document CN106237516B discloses a rechargeable implanted medical device, which adds a heat sink on the titanium casing of the implanted device on the outward side to reduce the heat generation of the implanted component battery, and also adds a shielding layer between the charging coil and the rechargeable battery inside the implanted device, where the shielding layer is required to achieve both electromagnetic shielding and heat conduction, and has high requirements for installation position and high production difficulty.
In the prior art, in order to avoid excessive heat generation of a battery of an implantation component, a shielding layer is generally adopted and arranged between a charging coil and a rechargeable battery inside an implantation device, and the problems that the requirements on the functions of the shielding layer are high, the requirement on the precision of an installation position is high, and the shielding and heat conduction or electric conduction effects are influenced once the position has deviation; in addition, the thickness of the implant device is increased after the shielding layer is added, so that the injury during the implantation is larger.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to overcome the technical defects of complicated internal structure, large thickness and large implantation wound of the rechargeable implantable medical device in the prior art caused by adding shielding layers and other components in order to solve the problem of charging and heating, so that the pulse generator with simple internal structure, small thickness and small implantation wound is provided.
The invention also provides an implanted sacral nerve stimulation system with the pulse generator.
To this end, the invention provides a pulse generator comprising:
the top cover is made of a biocompatible high polymer material;
the pulse generator main body is connected with the top cover plane;
the internal charging coil is arranged inside the top cover;
and the rechargeable battery is arranged in the pulse generator main body and is directly or indirectly electrically connected with the internal charging coil.
Preferably, the biocompatible polymer material is one or more of TPU, PEEK and nylon.
As a preferable scheme, the pulse generator further comprises a circuit board arranged inside the pulse generator main body; the inner charging coil is electrically connected with the circuit board, and the circuit board is electrically connected with the rechargeable battery.
As a preferable scheme, the top cover and the pulse generator main body are connected through a connecting structure plane, and the connecting structure comprises: the fixing claw is arranged on the pulse generator main body, and the fixing pin penetrates through the fixing claw and a fixing pin hole in the top cover to realize plane connection of the top cover and the pulse generator main body.
Preferably, the inner charging coil is arranged close to the inner side wall of the top cover.
As a preferable scheme, the portable terminal further comprises an antenna which is arranged inside the top cover and electrically connected with the circuit board.
Preferably, the stimulation electrode device further comprises an electrode connector arranged inside the top cover and used for being connected with the stimulation electrode or an extension wire connected with the stimulation electrode.
As a preferable scheme, the pulse generator further comprises a microprocessor module, which is arranged in the pulse generator main body, is electrically connected with the electrode connector through the circuit board and is used for generating an electrical stimulation pulse signal.
Preferably, a containing groove for placing the internal charging coil, the antenna or the electrode connector is arranged in the top cover and is bonded and fixed by liquid silicon rubber.
As a preferable scheme, a fixing screw is screwed on the electrode connector, one end of the fixing screw extends into an inner cavity of the electrode connector, into which the stimulating electrode or an extension line connected with the stimulating electrode is inserted, and the other end of the fixing screw is positioned outside the electrode connector;
the top cover opposite to the fixing screw is provided with a sealing plug hole, a screw sealing piece is arranged in the sealing plug hole, and a normally closed elastic operation hole for an operation tool to stretch into to drive the fixing screw to rotate so as to be screwed into or out of the inner cavity is formed in the screw sealing piece.
As a preferred scheme, the electrode connector further comprises an end sealing ring, wherein the end sealing ring is arranged on the top cover, one end of the end sealing ring is positioned in the top cover, the other end of the end sealing ring is positioned outside the top cover, and one end of the end sealing ring positioned in the top cover is connected with the electrode connector.
The present invention also provides an implantable sacral nerve stimulation system comprising:
a pulse generator;
one end of the stimulating electrode is connected with the pulse generator, and the other end of the stimulating electrode is suitable for being in contact with nerves;
an adjustable anchor for connecting the other end of the stimulating electrode with a corresponding nerve;
the extracorporeal control equipment can be in wireless communication with the pulse generator, can read the equipment information of the pulse generator and adjust stimulation parameters, and is provided with an external charging coil;
the pulse generator is the pulse generator of any one of the above, and the external charging coil can perform electromagnetic induction charging on the internal charging coil from the outside of the body.
The technical scheme provided by the invention has the following advantages:
1. the pulse generator comprises a top cover and a pulse generator main body which are in planar connection, wherein the planar connection means that when the pulse generator is implanted into a human body, orthographic projections of the top cover and the pulse generator main body on the skin of the human body are not overlapped, and the top cover and the pulse generator main body are both implanted into the human body in a fitting manner and are not overlapped; the pulse generator of the invention is characterized in that the internal charging coil is arranged inside the top cover and is electrically connected with the rechargeable battery arranged inside the pulse generator main body; because the top cap is made by biocompatible macromolecular material, when being located external charging device and just charging the interior charging coil that sets up in the top cap inside, the top cap does not produce the vortex, therefore the top cap shell can not self-heating to reduce the heat production, and then reduced the risk that charges and generate heat and lead to. Compared with the prior art, the pulse generator is creatively divided into two parts, the internal charging coil is arranged inside the top cover made of a biocompatible high polymer material, the eddy heat effect generated by wireless charging is avoided, the charging efficiency is improved, structures such as a shielding layer and the like are not needed, the internal design is simplified, and the whole thickness is thinner; in addition, compared with the prior art, the thickness of the pulse generator main body is thinner, so that the battery can be designed to be thicker in the thickness direction, and the battery capacity is increased; or the thickness of the pulse generator body is slightly increased, so that the plane occupation is reduced, thereby reducing the surgical trauma during the implantation.
2. According to the pulse generator, the biocompatible high polymer material can be one or more of TPU, PEEK and nylon, and the material can meet the requirement on biocompatibility, does not generate an eddy effect during charging, improves the charging efficiency and can avoid the problem of overhigh temperature.
3. The pulse generator also comprises a circuit board, wherein the circuit board is arranged in the pulse generator main body, an internal charging coil is electrically connected with the circuit board, and the circuit board is electrically connected with a rechargeable battery; the circuit board is arranged in the pulse generator main body and is separated from the internal charging coil, so that the electromagnetic influence on the circuit board during charging can be prevented.
4. According to the pulse generator, the top cover is in plane connection with the pulse generator through the connecting structure, the connecting structure comprises the fixing claw and the fixing pin, the fixing claw is connected with the pulse generator body, the fixing pin penetrates through the fixing claw and the fixing pin hole in the top cover, plane connection of the top cover and the pulse generator body is achieved, reasonable layout of the top cover and the pulse generator body is guaranteed, and the inner charging coil placed inside the top cover is prevented from being influenced by materials of the pulse generator body during charging.
5. According to the pulse generator, the inner charging coil is arranged close to the inner side wall of the top cover, when the pulse generator is implanted into a human body, the side wall faces the skin side of the human body, and when the pulse generator is charged, the outer charging coil and the inner charging coil of the in-vitro control device are oppositely charged, so that the spacing distance is small, and the charging efficiency is high.
6. The pulse generator also comprises an antenna, wherein the antenna is arranged inside the top cover and is electrically connected with the circuit board; the antenna setting is inside biocompatible polymer top cap, and the signal can not influenced by the titanium shell, and signal strength is higher.
7. The pulse generator also comprises an electrode connector which is arranged in the top cover and is used for being connected with the stimulating electrode or an extension line connected with the stimulating electrode; the electrode connector is arranged inside the top cover with fewer parts, the space occupation is more reasonable, the vacant space inside the pulse generator main body is small, the space utilization rate is high, and the compactness is good.
8. According to the pulse generator, the electrode connector is provided with the fixing screw, the screw sealing piece is installed at the position of the sealing plug hole of the top cover, the screw sealing piece is opposite to the position of the fixing screw which is screwed on the electrode connector, and an operation tool (such as a screwdriver and the like) can be used for screwing or unscrewing the fixing screw through the screw sealing piece to realize the fixing or loosening of the stimulating electrode penetrating into the electrode connector or the extension line connected with the stimulating electrode; the above arrangement can ensure firm fixation of the stimulating electrode and can ensure sealing, thereby ensuring safety.
9. The pulse generator also comprises an end sealing ring which is arranged on the top cover, one end of the end sealing ring is positioned in the top cover, the other end of the end sealing ring is positioned outside the top cover, one end of the end sealing ring positioned in the top cover is connected with the electrode connector, and the end sealing ring is provided with a through hole for the stimulation electrode to be inserted and connected with the electrode connector.
10. The invention also provides an implantable sacral nerve stimulation system, which comprises a pulse generator, a stimulation electrode, an adjustable fixing anchor and an in-vitro control device, wherein the pulse generator is the pulse generator, and has all the advantages of the pulse generator.
Drawings
To more clearly illustrate the technical solutions in the prior art or the embodiments of the present invention, the drawings used in the description of the prior art or the embodiments are briefly introduced below.
Fig. 1 is a schematic view of the overall structure of the pulse generator of the present invention after it is connected to a stimulation electrode.
Fig. 2 is a rear view of the pulse generator of fig. 1.
Fig. 3 is a schematic view of the structure of fig. 1 after the top cover is separated from the pulse generator main body.
Fig. 4 is a front view of the top cover.
Fig. 5 is a rear view of the top cover.
Fig. 6 is an exploded view of the structure of the top cover.
Fig. 7 is a schematic view of the structure of the inner coil.
Fig. 8 is a schematic view of another inner coil structure.
Fig. 9 is a schematic view of an application scenario of the implantable sacral nerve stimulation system of the present invention.
Reference numerals: 1. a top cover; 1-2 a-1-2 c, a fixing pin hole; 2. a pulse generator body; 2-1a to 2-1c, a fixing pin; 2-2a to 2-2c, a fixed claw; 3. an inner charging coil; 31. a first lead end of an inner charged coil; 32. a second lead end of the inner charged coil; 4. an antenna; 5. an electrode connector; 51. a set screw; 52. a screw seal; 521. normally closing the elastic operation hole; 53. an end seal ring; 6. a stimulation electrode; 7. an adjustable anchor; 8. an extracorporeal control device; 81. an external charging coil; 10. a pulse generator; 11. the plug hole is sealed.
Detailed Description
The technical solution of the present invention is described in detail below with reference to the accompanying drawings.
Example 1
The present embodiment provides a sacral nerve pulse generator, as shown in fig. 1-6, comprising: the top cover 1 is transparent and is made of biocompatible high polymer materials; the pulse generator main body 2 is connected with the top cover 1 in a plane manner; an inner charging coil 3 arranged inside the top cover 1; and the rechargeable battery is arranged in the pulse generator body 2 and is directly or indirectly electrically connected with the inner charging coil 3.
The term "plane connection" means that when the pulse generator of the present embodiment is implanted in a human body, the orthogonal projections of the top cover 1 and the pulse generator main body 2 on the skin of the human body do not overlap, and the top cover 1 and the pulse generator main body 2 are both implanted in the human body in a fitting manner and are not superimposed. In the pulse generator of the embodiment, the internal charging coil 3 is arranged inside the top cover 1 and is electrically connected with the rechargeable battery arranged inside the pulse generator main body 2; because top cap 1 is made by biocompatible macromolecular material, when being located external charging device and just charging the time of setting up the interior charging coil 3 in top cap 1 inside, top cap 1 does not produce the vortex, therefore top cap 1 shell can not self-heating to the heat production has been reduced, and then has reduced the risk that charges and generate heat and lead to. The pulse generator of the embodiment is creatively divided into two parts, the internal charging coil 3 is arranged inside the top cover 1 made of a biocompatible high polymer material, the eddy heat effect of wireless charging is avoided, the charging efficiency is improved, structures such as a shielding layer and the like are not needed, the internal design is simplified, and the whole thickness is thinner; in addition, the thickness of the pulse generator main body 2 is thinner, so that the battery can be designed to be thicker in the thickness direction, thereby increasing the battery capacity; or the thickness of the pulse generator body 2 is slightly increased, so that the planar occupation is reduced, thereby reducing the surgical trauma at the time of implantation.
Specifically in this embodiment, top cap 1 and impulse generator main part 2 are the cuboid structure of rounding all around, according to actual need, also can set up top cap 1 and impulse generator main part 2 into the structure of other adaptability.
The top cover 1 in the embodiment is made of TPU material, and the pulse generator main body 2 is a titanium shell. The material of the cap 1 may also be PEEK or nylon. The material can meet the requirement of biocompatibility, does not generate an eddy effect during charging, improves the charging efficiency, and can avoid the problem of overhigh temperature; conventionally, the inner charging coil 3 is arranged inside the titanium shell, and the charging efficiency is low.
The pulse generator also comprises a circuit board which is arranged inside the pulse generator main body 2; the inner charging coil 3 is electrically connected with the circuit board, and the circuit board is electrically connected with the rechargeable battery. The circuit board is provided inside the pulse generator body 2, and is provided separately from the internal charging coil 3, so that the electromagnetic influence on the circuit board during charging can be prevented.
As shown in fig. 7 to 8, the structure of the internal charging coil 3 is not limited, and may be circular, square or other shapes as long as it can be used for charging. As shown in fig. 5, the internal charging coil 3 enters the pulse generator body 2 through the first lead terminal 31 and the second lead terminal 32 of the internal charging coil, and is electrically connected to the rechargeable battery through the circuit board.
The top cap 1 with the pulse generator main part 2 passes through connection structure plane connection, connection structure includes: the fixed claws 2-2a, 2-2b and 2-2c and the fixed pins 2-1a, 2-1b and 2-1c are arranged on the pulse generator body 2, the fixed claws 2-2a, 2-2b and 2-2c are arranged on the pulse generator body 2, and the fixed pins 2-1a, 2-1b and 2-1c penetrate through the fixed claws 2-2a, 2-2b and 2-2c and the fixed pin holes 1-2a, 1-2b and 1-2c on the top cover 1, so that the planar connection between the top cover 1 and the pulse generator body 2 is realized. The connecting structure ensures the reasonable layout between the top cover 1 and the pulse generator main body 2, so that the inner charging coil 3 placed in the top cover 1 is free from the influence of the material of the pulse generator main body 2 during charging.
The antenna is characterized by further comprising an antenna 4, wherein the antenna 4 is arranged inside the top cover 1 and is electrically connected with the circuit board. Antenna 4 sets up inside biocompatible polymer top cap 1, and the signal can not be influenced by the titanium shell, and signal strength is higher. In this embodiment, the antenna 4 is a bluetooth antenna.
The electrode connector 5 is arranged inside the top cover 1 and is used for being connected with the stimulating electrode 6 or an extension line connected with the stimulating electrode 6. The electrode connector 5 is disposed inside the top cover 1 with fewer parts.
The pulse generator further comprises a microprocessor module which is arranged in the pulse generator main body 2, is electrically connected with the electrode connector 5 through the circuit board and is used for generating an electrical stimulation pulse signal.
The top cover 1 is internally provided with a containing groove for placing the internal charging coil 3, the antenna 4 or the electrode connector 5, and the containing groove is fixed by a buckle or liquid silicon rubber in a bonding way.
The electrode connector 5 is provided with a fixing screw 51, a screw sealing element 52 is arranged at the position of the sealing plug hole 11 of the top cover 1, the screw sealing element 52 is opposite to the position of the fixing screw 51 screwed on the electrode connector 5, and an operating tool (such as a screwdriver and the like) can be used for screwing or unscrewing the fixing screw 51 through the screw sealing element 52 to realize the fixing or loosening of the stimulating electrode 6 penetrating into the electrode connector 5 or the extension line connected with the stimulating electrode 6; the above arrangement can ensure both firm fixation and sealing of the stimulating electrode 6, thereby ensuring safety.
The electrode connector also comprises an end part sealing ring 53 which is arranged on the top cover 1, one end of the end part sealing ring 53 is positioned in the top cover 1, the other end of the end part sealing ring is positioned outside the top cover 1, and one end of the end part sealing ring 53 positioned in the top cover 1 is connected with the electrode connector 5; the end seal ring 53 is provided with a through hole for inserting the stimulating electrode 6 into connection with the electrode connector 5.
Example 2
The present embodiment provides an implantable sacral nerve stimulation system, as shown with reference to fig. 9, comprising: a pulse generator 10; a stimulating electrode 6 having one end connected to the pulse generator 10 and the other end adapted to contact a nerve; an adjustable fixing anchor 7 for connecting the other end of the stimulating electrode 6 with the corresponding nerve; an extracorporeal control device 8 capable of wirelessly communicating with the pulse generator 10, capable of reading device information of the pulse generator 10 and adjusting stimulation parameters, and having an external charging coil 81; the pulse generator 10 is the pulse generator described in embodiment 1, and the external charging coil 81 can electromagnetically inductively charge the internal charging coil 3 from the outside of the body.
This embodiment naturally provides an implantable sacral nerve stimulation system having all the advantages of the pulse generator described above, since the pulse generator of embodiment 1 is used.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.
Claims (10)
1. A pulse generator, characterized by: the method comprises the following steps:
the top cover (1) is made of a biocompatible high polymer material;
the pulse generator main body (2) is in plane connection with the top cover (1);
the internal charging coil (3) is arranged inside the top cover (1);
an antenna (4) arranged inside the top cover (1);
the electrode connector (5) is arranged in the top cover (1) and is used for being connected with the stimulating electrode (6) or an extension line connected with the stimulating electrode (6);
and the rechargeable battery is arranged in the pulse generator main body (2) and is directly or indirectly electrically connected with the internal charging coil (3).
2. A pulse generator as defined in claim 1, wherein: the biocompatible high polymer material is one or more of TPU, PEEK and nylon.
3. A pulse generator as defined in claim 1, wherein: the pulse generator also comprises a circuit board which is arranged inside the pulse generator main body (2); the inner charging coil (3) is electrically connected with the circuit board, and the circuit board is electrically connected with the rechargeable battery; the antenna (4) is electrically connected with the circuit board.
4. A pulse generator as defined in claim 1, wherein: the top cap (1) with the pulse generator main part (2) passes through connection structure plane connection, connection structure includes: the pulse generator comprises fixing claws (2-2a, 2-2b, 2-2c) and fixing pins (2-1a, 2-1b, 2-1c), wherein the fixing claws (2-2a, 2-2b, 2-2c) are arranged on the pulse generator body (2), and the fixing pins (2-1a, 2-1b, 2-1c) penetrate through the fixing claws (2-2a, 2-2b, 2-2c) and fixing pin holes (1-2a, 1-2b, 1-2c) in the top cover (1), so that the planar connection between the top cover (1) and the pulse generator body (2) is realized.
5. A pulse generator as defined in claim 1, wherein: the inner charging coil (3) is arranged close to the inner side wall of the top cover (1).
6. A pulse generator as defined in claim 1, wherein: the top cover (1) is internally provided with a containing groove for placing the internal charging coil (3), the antenna (4) or the electrode connector (5), and the containing groove is bonded and fixed by liquid silicon rubber.
7. A pulse generator as defined in claim 3, wherein: the electric stimulation pulse generator is characterized by further comprising a microprocessor module, wherein the microprocessor module is arranged in the pulse generator main body (2), is electrically connected with the electrode connector (5) through the circuit board and is used for generating an electric stimulation pulse signal.
8. Impulse generator as claimed in claim 6 or 7, characterized in:
a fixing screw (51) is screwed on the electrode connector (5), one end of the fixing screw (51) extends into an inner cavity of the electrode connector (5) for inserting the stimulating electrode (6) or an extension line connected with the stimulating electrode (6), and the other end of the fixing screw is positioned outside the electrode connector (5);
the top cover (1) opposite to the fixing screw (51) is provided with a sealing plug hole (11), a screw sealing element (52) is installed in the sealing plug hole (11), and the screw sealing element (52) is provided with a normally closed elastic operation hole (521) for an operation tool to extend into to drive the fixing screw (51) to rotate so as to be screwed in or out of the inner cavity.
9. The pulser of claim 8, wherein: the electrode connector is characterized by further comprising an end sealing ring (53) which is arranged on the top cover (1), one end of the end sealing ring is located inside the top cover (1), the other end of the end sealing ring is located outside the top cover (1), and one end of the end sealing ring (53) located inside the top cover (1) is connected with the electrode connector (5).
10. An implantable sacral nerve stimulation system comprising:
a pulse generator (10);
a stimulating electrode (6) having one end connected to the pulse generator (10) and the other end adapted to contact a nerve;
an adjustable anchor (7) for connecting the other end of the stimulating electrode (6) with a corresponding nerve;
an extracorporeal control device (8) which can communicate wirelessly with the pulse generator (10), can read device information of the pulse generator (10) and adjust stimulation parameters, and has an external charging coil (81);
the method is characterized in that: the pulse generator (10) according to any of claims 1-11, wherein the external charging coil (81) is capable of electromagnetically inductively charging the internal charging coil (3) from outside the body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010505332.0A CN111643815A (en) | 2020-06-05 | 2020-06-05 | Pulse generator and implantable sacral nerve stimulation system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN113769269A (en) * | 2021-09-07 | 2021-12-10 | 北京品驰医疗设备有限公司 | Implantable nerve stimulator suitable for human body |
| CN113769270A (en) * | 2021-09-07 | 2021-12-10 | 北京品驰医疗设备有限公司 | Implantable nerve stimulator suitable for human neck |
| CN118490988A (en) * | 2024-07-15 | 2024-08-16 | 苏州新云医疗设备有限公司 | Method for manufacturing implantable electric stimulator |
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Country or region after: China Address after: 100084 No. 1 Tsinghua Yuan, Beijing, Haidian District Applicant after: TSINGHUA University Applicant after: Beijing Pinchi Medical Equipment Co.,Ltd. Address before: 100084 No. 1 Tsinghua Yuan, Beijing, Haidian District Applicant before: TSINGHUA University Country or region before: China Applicant before: BEIJING PINS MEDICAL Co.,Ltd. |