CN111637669A

CN111637669A - Automatic storage liquid nitrogen container

Info

Publication number: CN111637669A
Application number: CN202010511852.2A
Authority: CN
Inventors: 王冠怡; 李胜; 肖宇; 钱开宇; 龚龑; 马浩力; 郭珊
Original assignee: Zhongnan Hospital of Wuhan University
Current assignee: Zhongnan Hospital of Wuhan University
Priority date: 2020-06-08
Filing date: 2020-06-08
Publication date: 2020-09-08

Abstract

The invention relates to an automatic storage liquid nitrogen tank, which comprises a liquid nitrogen tank, a freezing mechanism and a lifting mechanism, wherein the freezing mechanism is arranged on the liquid nitrogen tank; the top of the liquid nitrogen tank is provided with a tank opening; the freezing mechanism comprises a plurality of freezing racks; the freezing frames are uniformly distributed in the liquid nitrogen tank by taking the center of the liquid nitrogen tank as a circle center, each freezing frame is sequentially provided with a plurality of placing plates from top to bottom, the top of each placing plate is provided with a cross-shaped placing groove, a plurality of freezing boxes are arranged in each cross-shaped placing groove in a cross-shaped distribution mode, and each freezing frame is connected with the liquid nitrogen tank through a first rotating mechanism; the lifting mechanism comprises a supporting frame; the lifting plate is arranged on the support frame and connected with the support frame through a lifting mechanism, and the bottom of the lifting plate is connected with the top of the mounting plate through a second rotating mechanism. The invention has the beneficial effects that: this kind of automatic storage liquid nitrogen container can accurately take out required freezing box in the liquid nitrogen container, and degree of automation is high, has reduced manual operation's the degree of difficulty, avoids the sample to freeze and thaw repeatedly, improves sample storage quality.

Description

Automatic storage liquid nitrogen container

Technical Field

The invention relates to the technical field of biological sample storage devices, in particular to an automatic storage liquid nitrogen tank.

Background

The freezing storage of liquid nitrogen is one of the main methods for long-term preservation of biological cells, tissues and organs, the liquid nitrogen is from air, and the main gas components contained in the air comprise oxygen and nitrogen. Wherein, the nitrogen accounts for about 78.09% of the air, and the liquid nitrogen is liquefied nitrogen. The liquid nitrogen tank is commonly called a biological liquid nitrogen container and can be used for medical treatment, biological research, college experiments, chromatographic experiments and epidemic prevention units. In medical treatment and scientific research, the biological preservative is mainly used as a storage type liquid nitrogen container for preserving active biological materials such as embryos, stem cells, skins, internal organs, vaccines and the like for a long time indoors. When the biological material is frozen, the freezing tube filled with the biological material is generally placed in a freezing box, and then the freezing box is placed on a freezing frame in a liquid nitrogen tank, but the biological material is generally manually operated in the extraction process. The manual operation has the defects of complicated operation and long time consumption; and the constraint of the freezing storage frame is that the non-target freezing storage box is often taken out when the target freezing storage box is taken, so that sample freezing and thawing are easily caused, the quality of the sample is reduced, and subsequent scientific research tests are influenced.

Disclosure of Invention

The invention aims to solve the technical problem of providing an automatic storage liquid nitrogen tank and solve the defects of the prior art.

The technical scheme for solving the technical problems is as follows: an automatic storage liquid nitrogen tank comprises a liquid nitrogen tank, a freezing mechanism and a lifting mechanism; the top of the liquid nitrogen tank is provided with a tank opening; the freezing mechanism comprises a plurality of freezing racks; the freezing frames are uniformly distributed in the liquid nitrogen tank by taking the center of the liquid nitrogen tank as a circle center, each freezing frame is sequentially provided with a plurality of placing plates from top to bottom, the top of each placing plate is provided with a cross-shaped placing groove, a plurality of freezing boxes are arranged in each cross-shaped placing groove in a cross-shaped distribution mode, and each freezing frame is connected with the liquid nitrogen tank through a first rotating mechanism; the lifting mechanism comprises a supporting frame; the automatic freezing and storing device is characterized in that a lifting plate is arranged on the support frame and connected with the support frame through a lifting mechanism, the bottom of the lifting plate is connected with the top of the mounting plate through a second rotating mechanism, mechanical arms are mounted on two sides of the bottom of the mounting plate, and the freezing and storing mechanism and the lifting mechanism are respectively electrically connected with the PLC.

The invention has the beneficial effects that: this kind of automatic storage liquid nitrogen container can accurately take out required freezing box in the liquid nitrogen container, and degree of automation is high, has reduced manual operation's the degree of difficulty, avoids the sample to freeze and thaw repeatedly to improve sample storage quality.

Further: the freezing frame comprises two square frames which are vertical to each other; the placing plates are sequentially arranged in the two square frames from top to bottom.

The beneficial effects of the further scheme are as follows: the freezing frame is simple in structure, reasonable in design and high in strength.

Further: the first rotating mechanism comprises a first motor, an upper rotating shaft and a lower rotating shaft; the upper rotating shaft and the lower rotating shaft are respectively arranged at the top joint and the bottom joint of the square frame, the upper end of the upper rotating shaft penetrates through the liquid nitrogen tank and is connected with the first motor output shaft, and the lower end of the lower rotating shaft is rotatably connected with the liquid nitrogen tank.

The beneficial effects of the further scheme are as follows: can drive through first motor and go up the pivot and rotate to drive two square frame and rotate, the pivot rotates with the liquid nitrogen container to be connected down simultaneously, can make two square frame more stable at the pivoted in-process.

Further: the support frame comprises an annular mounting plate, a support rod and a top plate; the annular mounting panel is installed liquid nitrogen tank top, the jar mouth is established in the annular mounting panel, the annular mounting panel top is through many the bracing piece with the roof bottom is connected, the lifter plate is established the annular mounting panel with between the roof and with many bracing piece sliding connection.

The beneficial effects of the further scheme are as follows: this kind of support frame simple structure, lifter plate and many spinal branchs vaulting pole sliding connection simultaneously can make the lifter plate more stable at the in-process that goes up and down.

Further: the lifting mechanism comprises a control box and a second motor; the improved lifting plate is characterized in that a threaded sleeve is arranged in the control box, the upper end and the lower end of the threaded sleeve are respectively installed at the top and the bottom of the control box through bearings, a driven gear is arranged on the outer side wall of the threaded sleeve and meshed with a driving gear, the driving gear is connected with an output shaft of a second motor, a threaded rod is arranged in the threaded sleeve, and the lower end of the threaded rod is connected with the top of the lifting plate.

The beneficial effects of the further scheme are as follows: the second motor accessible driving gear and driven gear drive thread bush rotate, and the thread bush drives the threaded rod automatic rising.

Further: the second rotating mechanism comprises a third motor and a transmission rod; the third motor is installed in the bottom of the lifting plate, an output shaft of the third motor is connected with the upper end of the transmission rod, and the lower end of the transmission rod is connected with the top of the mounting plate.

The beneficial effects of the further scheme are as follows: the third motor can drive the transmission rod to rotate, and the transmission rod drives the mounting plate to rotate automatically.

Further: the manipulator comprises a first electric telescopic rod and a second electric telescopic rod; first electric telescopic handle is installed the mounting panel bottom, install first electric telescopic handle lower extreme second electric telescopic handle, second electric telescopic handle keeps away from first electric telescopic handle's one end is installed U-shaped splint, be equipped with the clamp splice in the U-shaped splint, the clamp splice is connected with third electric telescopic handle, it is equipped with the promotion piece to freeze and deposit box top.

The beneficial effects of the further scheme are as follows: when extracting the cryopreserved box, drive U-shaped splint lateral shifting through the electronic flexible second, make the U-shaped splint be located cryopreserved box top, then drive the U-shaped splint through first electric telescopic handle and descend, will promote the piece card and go into in the U-shaped splint, then drive the clamp splice through third electric telescopic handle and remove and fix the piece that will promote in the U-shaped splint, second electric telescopic handle and first electric telescopic handle restore to original state at last, can take out the cryopreserved box from the cross standing groove.

Further: the grapple includes a base plate; base plate one side both ends all are equipped with first fixture block, base plate and two be equipped with the second fixture block in the middle of the relative one side of first fixture block, the poppet is individual and is the distribution of article font cryopreserved box top, the cross-section of poppet is the T font.

The beneficial effect of above-mentioned further scheme is that, second fixture block and two first fixture blocks can be blocked in between the three hoisting head to can realize being connected grapple and three hoisting head.

Drawings

FIG. 1 is a schematic structural diagram of an automatic storage liquid nitrogen tank according to an embodiment of the present invention;

FIG. 2 is a schematic structural diagram of a freezing mechanism according to an embodiment of the present invention;

FIG. 3 is a schematic structural diagram of a lifting mechanism according to an embodiment of the present invention;

FIG. 4 is a schematic diagram of the internal structure of the control box according to the embodiment of the present invention;

FIG. 5 is a schematic structural diagram of a robot according to an embodiment of the present invention;

FIG. 6 is a schematic structural diagram of a cryopreservation box according to an embodiment of the invention;

in the figure: 1. a liquid nitrogen tank; 11. a tank opening; 2. a freezing and storing mechanism; 21. freezing and storing the shelves; 211. a square frame; 22. placing the plate; 221. a cross-shaped placing groove; 23. freezing and storing the box; 231. a lifting block; 24. a first rotating mechanism; 241. a first motor; 242. an upper rotating shaft; 243. a lower rotating shaft; 3. a lifting mechanism; 31. a support frame; 311. an annular mounting plate; 312. a support bar; 313. a top plate; 32. a lifting plate; 33. a lifting mechanism; 331. a control box; 332. a threaded sleeve; 333. a bearing; 334. a driven gear; 335. a driving gear; 336. a second motor; 337. a threaded rod; 34. a second rotating mechanism; 341. a second motor; 34. a transmission rod; 35. mounting a plate; 36. a manipulator; 361. a first electric telescopic rod; 362. a second electric telescopic rod; 363. a U-shaped splint; 364. a clamping block; 365. and a third electric telescopic rod.

Detailed Description

The principles and features of this invention are described below in conjunction with the following drawings, which are set forth by way of illustration only and are not intended to limit the scope of the invention.

Example one

As shown in fig. 1-6, an automatic storage liquid nitrogen container comprises a liquid nitrogen container 1, a freezing mechanism 2 and a lifting mechanism 3; the top of the liquid nitrogen tank 1 is provided with a tank opening 11; the freezing mechanism 2 comprises a plurality of freezing racks 21; the freezing frames 21 are uniformly distributed in the liquid nitrogen tank 1 by taking the center of the liquid nitrogen tank 1 as a circle center, each freezing frame 21 is sequentially provided with a plurality of placing plates 22 from top to bottom, the top of each placing plate 22 is provided with a cross-shaped placing groove 221, a plurality of freezing boxes 23 are arranged in each placing groove 221 in a cross-shaped distribution mode, for example, five freezing boxes 23, nine freezing boxes 23 and the like are arranged in each placing groove 221, and each freezing frame 21 is connected with the liquid nitrogen tank 1 through a first rotating mechanism 24; the lifting mechanism 3 includes a support frame 31; be equipped with lifter plate 32 on the support frame 31, lifter plate 32 passes through elevating system 33 and is connected 31 with the support frame, and lifter plate 32 bottom is connected with mounting panel 35 top through second rotary mechanism 34, and manipulator 36 is all installed to mounting panel 35 bottom both sides, freezes to deposit mechanism 2 and hoist mechanism 3 and is connected with PLC controller 4 electricity respectively.

The freezing box 23 at the center of the cross-shaped placing groove 221 is a cross-shaped freezing box for placing the inner side of the placing groove 221, the rest is the freezing storage box at the outer side of the cross-shaped placing groove 221, when the freezing storage box to be extracted is the freezing storage box 23 at the outer side of the cross-shaped placing groove 221, the lifting mechanism 33 is controlled by a control panel on the PLC controller to drive the two mechanical hands 36 to descend, when the two mechanical hands 36 descend to be at the same height with the freezing box 23 to be extracted, then the first rotating mechanism 24 is controlled by a control panel on the PLC controller to drive the freezing box 23 to be extracted to rotate, the second rotating mechanism 34 drives the two mechanical hands 36 to rotate, so that one of the mechanical hands 36 is close to the freezing storage box to be extracted, then one of the manipulators 36 is controlled by a control panel on the PLC to grab the cryopreservation box 23 to be extracted, and finally the control panel on the PLC controls the lifting mechanism 33 to drive the cryopreservation box 23 to be extracted to ascend and extract from the liquid nitrogen tank.

When the freezing box 23 to be extracted is the freezing box at the inner side of the cross-shaped placing groove 221, the operation is the same as that of the freezing box 23 at the outer side of the cross-shaped placing groove 221, one of the mechanical hands 36 is controlled by a control panel on the PLC to grab one freezing storage box 23 outside the cross-shaped placing groove 221, then the second rotating mechanism 34 is controlled by a control panel on the PLC controller to drive the other manipulator 36 to rotate 180 degrees, and controls another manipulator 36 to grab the freezing box to be picked up through a control panel on the PLC controller, then the second rotating mechanism 34 is controlled by the control panel on the PLC controller to drive the two manipulators to rotate to the original positions, and the freezing box 23 which is firstly grabbed is put back to the original position, and finally the lifting mechanism 33 is controlled by the control panel on the PLC controller to drive the freezing box 23 which needs to be extracted to ascend and be extracted from the liquid nitrogen tank 1.

When it is necessary to put the freezing box 23 into the liquid nitrogen tank 1, the operation for extracting the freezing box 23 is reversed as described above.

Example two

The freezing frame 21 comprises two square frames 211 which are vertical to each other; the plurality of placing plates 22 are provided in the two square frames 211 in this order from top to bottom.

The first rotating mechanism 24 includes a first motor 241, an upper rotating shaft 242, and a lower rotating shaft 243; the upper rotating shaft 242 and the lower rotating shaft 243 are respectively installed at the top connection part and the bottom connection part of the two square frames 211, the upper end of the upper rotating shaft 241 penetrates through the liquid nitrogen tank 1 to be connected with the output shaft of the first motor 241, and the lower end of the lower rotating shaft 243 is rotatably connected with the liquid nitrogen tank 1.

EXAMPLE III

The support bracket 31 includes a ring-shaped mounting plate 311, a support rod 312, and a top plate 313; the annular mounting plate 311 is installed on the top of the liquid nitrogen tank 1, the tank opening 11 is arranged in the annular mounting plate 311, the top of the annular mounting plate 311 is connected with the bottom of the top plate 313 through a plurality of support rods 312, and the lifting plate 32 is arranged between the annular mounting plate 311 and the top plate 313 and is in sliding connection with the plurality of support rods 312.

Example four

The lifting mechanism 33 includes a control box 331 and a second motor 336; a threaded sleeve 332 is arranged in the control box 331, the upper end and the lower end of the threaded sleeve 332 are respectively installed at the top and the bottom of the control box 331 through bearings 333, a driven gear 334 is arranged on the outer side wall of the threaded sleeve 332, the driven gear 334 is meshed with a driving gear 335, the driving gear 335 is connected with an output shaft of a second motor 336, a threaded rod 337 is arranged in the threaded sleeve 332, and the lower end of the threaded rod 337 is connected with the top of the lifting plate 32.

EXAMPLE five

The second rotating mechanism 34 includes a third motor 341 and a transmission lever 342; the third motor 341 is installed at the bottom of the lifting plate 32, the output shaft of the third motor 341 is connected with the upper end of the transmission rod 342, and the lower end of the transmission rod 342 is connected with the top of the installation plate 35.

EXAMPLE six

The manipulator 36 comprises a first electric telescopic rod 361 and a second electric telescopic rod 362; first electric telescopic handle 361 installs in the mounting panel 35 bottom, and second electric telescopic handle 362 is installed to first electric telescopic handle 361 lower extreme, and U-shaped splint 363 is installed to the one end that first electric telescopic handle 361 was kept away from to second electric telescopic handle 362, is equipped with clamp 364 in the U-shaped splint, and clamp 364 is connected with third electric telescopic handle 365, freezes and deposits the box 23 top and is equipped with promotion piece 231.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.

Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.

Claims

1. An automatic storage liquid nitrogen tank is characterized by comprising a liquid nitrogen tank (1), a freezing mechanism (2) and a lifting mechanism (3); the top of the liquid nitrogen tank (1) is provided with a tank opening (11); the freezing mechanism (2) comprises a plurality of freezing racks (21); the freezing frames (21) are uniformly distributed in the liquid nitrogen tank (1) by taking the center of the liquid nitrogen tank (1) as a circle center, each freezing frame (21) is sequentially provided with a plurality of placing plates (22) from top to bottom, the top of each placing plate (22) is provided with a cross-shaped placing groove (221), a plurality of freezing boxes (23) are arranged in each cross-shaped placing groove (221) in a cross-shaped distribution mode, and each freezing frame (21) is connected with the liquid nitrogen tank (1) through a first rotating mechanism (24) respectively; the lifting mechanism (3) comprises a support frame (31); be equipped with lifter plate (32) on support frame (31), lifter plate (32) through elevating system (33) with support frame (31) are connected, lifter plate (32) bottom is connected with mounting panel (35) top through second rotary mechanism (34), manipulator (36) are all installed to mounting panel (35) bottom both sides, freeze and deposit mechanism (2) with hoist mechanism (3) are connected with PLC controller (4) electricity respectively.

2. The tank, according to claim 1, characterized in that said freezing rack (21) comprises two square frames (211) perpendicular to each other; the plurality of placing plates (22) are sequentially arranged in the two square frames (211) from top to bottom.

3. The automated storage liquid nitrogen tank of claim 2, wherein the first rotation mechanism (24) comprises a first motor (241), an upper rotating shaft (242) and a lower rotating shaft (243); the upper rotating shaft (242) and the lower rotating shaft (243) are respectively arranged at the top connecting part and the bottom connecting part of the square frame (211), the upper end of the upper rotating shaft (241) penetrates through the liquid nitrogen tank (1) to be connected with the output shaft of the first motor (241), and the lower end of the lower rotating shaft (243) is rotatably connected with the liquid nitrogen tank (1).

4. The automated storage liquid nitrogen tank of claim 1, wherein the support frame (31) comprises a ring-shaped mounting plate (311), a support rod (312) and a top plate (313); annular mounting panel (311) are installed liquid nitrogen container (1) top, establish jar mouth (11) in annular mounting panel (311), annular mounting panel (311) top is through many bracing piece (312) with roof (313) bottom is connected, lifter plate (32) are established annular mounting panel (311) with between roof (313) and with many bracing piece (312) sliding connection.

5. The automated storage liquid nitrogen tank of claim 1, wherein the lifting mechanism (33) comprises a control box (331) and a second motor (336); be equipped with thread bush (332) in control box (331), install through bearing (333) respectively thread bush (332) upper end and lower extreme control box (331) top and bottom, thread bush (332) lateral wall is equipped with driven gear (334), driven gear (334) and driving gear (335) meshing, driving gear (335) with the output shaft of second motor (336), be equipped with threaded rod (337) in thread bush (332), threaded rod (337) lower extreme with lifter plate (32) top is connected.

6. The tank according to claim 1, characterized in that said second rotation mechanism (34) comprises a third motor (341) and a transmission rod (342); the third motor (341) is installed at the bottom of the lifting plate (32), an output shaft of the third motor (341) is connected with the upper end of the transmission rod (342), and the lower end of the transmission rod (342) is connected with the top of the installation plate (35).

7. The automated storage liquid nitrogen tank of claim 1, wherein the manipulator (36) comprises a first electric telescopic rod (361) and a second electric telescopic rod (362); first electric telescopic handle (361) is installed mounting panel (35) bottom, install first electric telescopic handle (361) lower extreme second electric telescopic handle (362), second electric telescopic handle (362) are kept away from U-shaped splint (363) are installed to the one end of first electric telescopic handle (361), be equipped with clamp splice (364) in the U-shaped splint, clamp splice (364) are connected with third electric telescopic handle (365), it is equipped with lift block (231) to freeze and deposits box (23) top.