CN111631838A - Tail vein catheter system - Google Patents
Tail vein catheter system Download PDFInfo
- Publication number
- CN111631838A CN111631838A CN202010575734.8A CN202010575734A CN111631838A CN 111631838 A CN111631838 A CN 111631838A CN 202010575734 A CN202010575734 A CN 202010575734A CN 111631838 A CN111631838 A CN 111631838A
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- Prior art keywords
- arc
- shaped claw
- tail
- mouse
- groove
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F21—LIGHTING
- F21V—FUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
- F21V21/00—Supporting, suspending, or attaching arrangements for lighting devices; Hand grips
- F21V21/14—Adjustable mountings
- F21V21/22—Adjustable mountings telescopic
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F21—LIGHTING
- F21V—FUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
- F21V33/00—Structural combinations of lighting devices with other articles, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Husbandry (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The invention provides a tail vein catheter system, which belongs to the technical field of medical experimental equipment and comprises an operation table, a clamping device and an angle adjusting mechanism; the top of the operating platform is provided with a groove, and the clamping device is arranged in the groove and comprises a first arc-shaped claw and a second arc-shaped claw; one side of the first arc-shaped claw is fixedly provided with a hinged shaft along the axial direction, and two ends of the hinged shaft are rotatably connected with two ends of the groove through bearings; one side of the second arc-shaped claw is hinged with the hinge shaft, and the arc surfaces of the first arc-shaped claw and the second arc-shaped claw are opposite; a plurality of clamping teeth are uniformly arranged on one side, opposite to the first arc-shaped claw and the second arc-shaped claw, along the length direction and used for inserting the mouse head and the mouse tail limiting plate; one end of the first arc-shaped claw and one end of the second arc-shaped claw are provided with clamping pieces for adjusting the opening degree; a square groove is formed in one end of the operating platform, and the angle adjusting mechanism is arranged at the bottom of the square groove and used for adjusting the clamping device to rotate in the groove. The device realizes fixing the tail of the mouse, increases the accuracy of administration, and simultaneously conforms to the ethical spirit of animals.
Description
Technical Field
The invention relates to the technical field of medical experimental equipment, in particular to a tail vein catheter system.
Background
The similarity between the gene sequence of a mouse and the gene sequence of a human being is the closest, so that the mouse participates in pharmacological experiments and clinical experiments of medicines and researches on safety, toxicity and potency of biological products, cosmetics and industrial products, when the mouse is used for experimental research, a product to be researched is generally administrated in a liquid mode through the tail vein of the mouse, however, in the administration process, the mouse is fixed by using a fixing device because the mouse is easy to move and the accuracy of rat tail vein injection is influenced.
Traditional mouse fixer simple structure, can not adjust the volume of fixer according to the size of mouse, can't carry out better spacing to all mice, and then lead to the unable smooth tail vein to the mouse study of dosing.
Thus, the present application proposes a new tail vein catheterization system capable of administering drugs to the tail vein of rats.
Disclosure of Invention
In order to solve the problems, the invention aims to provide a tail vein catheterization system for old rat tail vein administration.
In order to achieve the above purpose, the present invention provides the following technical solutions.
The tail vein catheterization system comprises an operation table, a clamping device and an angle adjusting mechanism; the top of the operating platform is provided with a groove, and the clamping device is arranged in the groove;
the clamping device comprises a first arc-shaped claw and a second arc-shaped claw; one side of the first arc-shaped claw is fixedly provided with a hinged shaft along the axial direction, and two ends of the hinged shaft are rotatably connected with two ends of the groove through bearings; one side of the second arc-shaped claw is hinged with the hinge shaft, and the arc surfaces of the first arc-shaped claw and the second arc-shaped claw are opposite; a plurality of clamping teeth are uniformly arranged on one side, opposite to the first arc-shaped claw and the second arc-shaped claw, along the length direction; a mouse head limiting net and a mouse tail limiting plate are inserted between the two clamping teeth, a cavity for accommodating a laboratory mouse is formed between the mouse head limiting net and the mouse tail limiting plate, and an outlet for allowing a mouse tail to penetrate out is formed in the mouse tail limiting plate;
one end of the first arc-shaped claw and one end of the second arc-shaped claw are provided with clamping pieces for adjusting the opening degree;
one end of the operating platform is provided with a square groove, and the angle adjusting mechanism is arranged at the bottom of the square groove and used for adjusting the clamping device to rotate in the groove;
the top of the operating platform is provided with a tail clamp, and the tail clamp is positioned at one end of the groove and is fixed through a fixing block; a heating plate is arranged below the tail clamp; the top of the operation table is provided with a controller, and the heating plate is electrically connected with the controller.
Preferably, the clamping piece comprises a fixing plate which is rotatably connected with one end of the second arc-shaped claw; a plurality of clamping joints are uniformly arranged along the length direction of the fixing plate; a clamping groove is formed in one end of the first arc-shaped claw, and any one of the clamping heads is matched with the clamping groove.
Preferably, the angle adjusting mechanism comprises a handle and limiting rods which are fixedly connected with the handle and are arranged side by side; the handle is arranged in the square groove, and the hinge shaft penetrates through one end of the groove and is fixedly connected with the handle; the limiting rod comprises a first sleeve and a loop bar arranged in the first sleeve; the sleeve rod is connected with the first sleeve through a spring, and the first sleeve is fixedly connected with the handle; one end of the operating platform surrounds the handle and is evenly provided with a plurality of jacks, and the tail end of the loop bar is matched with any one of the jacks.
Preferably, the upper ends of the mouse head limiting net and the mouse tail limiting plate are both limiting plates, and the lower ends of the mouse head limiting net and the mouse tail limiting plate are respectively provided with a baffle and a limiting net which are matched with the cavity.
Preferably, one end of the top surface of the operating platform is arranged in a downward inclined mode, and an included angle between the top surface of the operating platform and the bottom surface of the operating platform is 10-30 degrees.
Preferably, the side wall of the operating platform is provided with a longitudinal support rod, and the end part of the longitudinal support rod is fixedly provided with a transverse support rod; a second sleeve is sleeved outside the transverse supporting rod, a plurality of threaded holes are formed in the transverse supporting rod along the length direction, and a plurality of through holes matched with the threaded holes are formed in the second sleeve along the length direction; any one through hole is connected with the threaded hole through a bolt, and a lighting lamp is installed at the tail end of the second sleeve; and a placing groove for placing the magnifier is formed in the top surface of the operating platform.
Preferably, the side wall of the operating platform is provided with a placing rack for placing the mouse head limiting net and the mouse tail limiting plate.
The invention has the beneficial effects that:
(1) according to the clamping device, the clamping piece is arranged, so that the opening degree between the first arc-shaped claw and the second arc-shaped claw can be reasonably adjusted according to the size of a mouse, the volume of the clamping device can be reasonably adjusted, and the mouse is clamped in the clamping device;
(2) according to the invention, the operation table is provided with the square groove and the angle adjusting mechanism, so that the clamping device can be rotated by a certain angle, and the experiment personnel can conveniently administer the drug to the tail vein on the left side or the right side of the tail of the mouse limited in the clamping device on the premise of not influencing the injection operation of the experiment personnel;
(3) according to the mouse clamping device, the mouse head limiting net and the mouse tail limiting plate are respectively inserted into a gap reserved between two adjacent clamping teeth, so that a mouse clamped in the clamping device is limited, and the mouse is prevented from moving freely; meanwhile, the tail of the mouse penetrates out of the opening formed in the tail fixing plate to limit the random movement of the mouse tail, so that the injury to the mouse during administration is reduced, the administration accuracy is improved, and the animal ethics spirit is met;
(4) according to the invention, the included angle of 10-30 degrees is formed between the top surface of the operating platform and the bottom surface of the operating platform, so that the tail of the mouse can naturally droop; through setting up the tail and pressing from both sides, the purpose blocks the vascular backward flow of vein of mouse tail, makes blood vessel congestion, and the old rat tail vein of looking for more clearly through setting up magnifying glass, light, the afterbody vein of seeing clearly the mouse that can be clear conveniently doses, helps showing the blood vessel through setting up the hot plate, helps improving the accuracy of dosing simultaneously.
The invention is further described with reference to the following figures and examples.
Drawings
FIG. 1 is an overall block diagram of a tail vein catheter system in accordance with an embodiment of the present invention;
FIG. 2 is a block diagram of an operator station for a tail vein catheterization system in accordance with an embodiment of the present invention;
FIG. 3 is a block diagram of a clamping device of the tail vein catheter system of an embodiment of the present invention;
FIG. 4 is a diagram of a tail vein placement system with a rat tail restriction plate configuration according to an embodiment of the present invention;
fig. 5 is a structure diagram of a rat head limiting net of the tail vein catheterization system in the embodiment of the present invention.
In the figure: 1. an operation table; 2. a groove; 3. a first arcuate jaw; 4. a second arcuate jaw; 5. clamping teeth; 6. a fixing plate; 7. a mouse head limiting net; 8. a tail limiting plate; 9. a fixed block; 10. a tail clip; 11. a placement groove; 12. heating plates; 13. a handle; 14. a first sleeve; 15. a loop bar; 16. a jack; 17. an illuminating lamp; 18. a second sleeve; 19. a longitudinal support bar; 20. a transverse support bar; 21. a clamping head; 22. and (4) hinging the shaft.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Examples
The tail vein catheterization system is shown in figures 1-4 and comprises an operation table 1, a clamping device and an angle adjusting mechanism; the top of the operating platform 1 is provided with a groove 2, and the clamping device is arranged in the groove 2;
the clamping device comprises a first arc-shaped claw 3 and a second arc-shaped claw 4, as shown in figure 3; one side of the first arc-shaped claw 4 is fixedly provided with a hinged shaft 22 along the axial direction, and two ends of the hinged shaft 22 are rotatably connected with two ends of the groove 2 through bearings; one side of the second arc-shaped claw 4 is hinged with the hinge shaft 22, and the arc surfaces of the first arc-shaped claw 3 and the second arc-shaped claw 4 are opposite; a plurality of clamping teeth 5 are uniformly arranged on one side, opposite to the first arc-shaped claw 3 and the second arc-shaped claw 4, along the length direction; a mouse head limiting net 7 and a mouse tail limiting plate 8 are inserted between the two latch teeth 5, a cavity for accommodating a laboratory mouse is formed between the mouse head limiting net 7 and the mouse tail limiting plate 8, and an outlet for allowing a mouse tail to penetrate out is formed in the mouse tail limiting plate 8;
one end of the first arc-shaped claw 3 and one end of the second arc-shaped claw 4 are provided with clamping pieces for adjusting the opening degree;
one end of the operating platform 1 is provided with a square groove, and the angle adjusting mechanism is arranged at the bottom of the square groove and used for adjusting the clamping device to rotate in the groove 2;
a tail clamp 10 is arranged at the top of the operating platform 1, the tail clamp 10 is positioned at one end of the groove 2 and is fixed through a fixing block 9, as shown in fig. 2; a heating plate 12 is arranged below the tail clamp 10; the top of the operation table 1 is provided with a controller, and the heating plate 15 is electrically connected with the controller.
Further, the clamping piece comprises a fixing plate 6 which is rotatably connected with one end of the second arc-shaped claw 4; a plurality of clamping joints 21 are uniformly arranged along the length direction of the fixing plate 6; one end of the first arc-shaped claw 3 is provided with a clamping groove, and any one clamping connector 21 is matched with the clamping groove.
Preferably, as shown in fig. 1, the angle adjusting mechanism includes a handle 13 and a stop lever fixedly connected to the handle 13 and arranged side by side; the handle 13 is arranged in the square groove, and the hinge shaft 22 passes through one end of the groove 2 and is fixedly connected with the handle 13; the limiting rod comprises a first sleeve 14 and a loop bar 15 arranged in the first sleeve 14; the loop bar 15 is connected with the first sleeve 14 through a spring, and the first sleeve 14 is fixedly connected with the handle 13; one end of the operating platform 1 is uniformly provided with a plurality of jacks 16 surrounding the handle 13, and the tail end of the loop bar 15 is matched with any one jack 16.
Preferably, the upper ends of the mouse head limiting plate 7 and the mouse tail limiting plate 8 are both limiting plates, and the lower ends are respectively a baffle and a limiting net which are matched with the cavity, as shown in fig. 4 and 5.
In addition, one end of the top surface of the operating platform 1 is arranged in a downward inclined mode, and the included angle between the top surface of the operating platform 1 and the bottom surface of the operating platform 1 is 10-30 degrees.
Preferably, the side wall of the operating table 1 is provided with a longitudinal support rod 19, and the end of the longitudinal support rod 19 is fixedly provided with a transverse support rod 20; a second sleeve 18 is sleeved outside the transverse supporting rod 20, a plurality of threaded holes are formed in the transverse supporting rod 20 along the length direction, and a plurality of through holes matched with the threaded holes are formed in the second sleeve 18 along the length direction; any one through hole is connected with the threaded hole through a bolt, and the tail end of the second sleeve 18 is provided with an illuminating lamp 17; the top surface of the operating platform 1 is provided with a placing groove 11 for placing the magnifier.
In addition, a placing rack for placing a mouse head limiting net 7 and a mouse tail limiting plate 8 is arranged on the side wall of the operating platform 1.
In the present embodiment, the first and second electrodes are,
before the tail vein administration is carried out on the mouse, the mouse needs to be fixed, the volume of a clamping device formed by enclosing a first arc-shaped claw 3 and a second arc-shaped claw 4 is reasonably adjusted according to the size of an experimental mouse, the mouse is placed in the clamping device, and then a clamping piece arranged at the end part is buckled, so that the clamping device is suitable for limiting the mice with different sizes, and the mouse is prone in a fixed clamping device or lies in the mouse clamping device in a semi-lateral horizontal mode;
in order to administer medicine to the tail vein of a mouse, the mouse is required to be limited to move freely in the clamping device, the mouse head limiting net 7 and the mouse tail limiting plate 8 are respectively inserted into a gap reserved between two adjacent clamping teeth 5, the mouse is completely limited in a space enclosed by the mouse head limiting net 7, the mouse tail limiting plate 8, the clamping device and the groove 2, and the tail is further limited through a mouse tail outlet in the middle of the mouse tail limiting plate 8; the arrangement can limit the mice clamped in the clamping device, avoid the injury to the mice during operation and improve the accuracy of the experiment;
in order to facilitate the experimenter to administer the drug to the tail vein on the left side or the right side of the tail of the mouse, the angle of the clamping device needs to be adjusted; the loop bar 15 clamped in the jack 16 is pulled out, the handle 13 is rotated, and then the articulated shaft 22 is rotated, so that the rotation of the whole clamping device is formed; after the angle is adjusted, the loop bar 15 is inserted into the corresponding jack 16, and the loop bar 15 is subjected to the elasticity of the spring because the spring is arranged between the loop bar 15 and the first sleeve 14, so that the loop bar can be stably kept without falling after being inserted into the jack 16, and the angle is adjusted;
finally, the rat tail is fixed through a tail clip 10, the backflow of venous blood vessels of the rat tail is blocked, blood vessels are congested, and the vein of the rat tail is searched more clearly; the heating plate 12 is opened to expose blood vessels, so that the blood flow is accelerated, and the accuracy of medicine administration is improved; remove scalable light 17 to take the magnifying glass of placing in standing groove 11 according to the demand, carry out the afterbody and administer the processing.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. The tail vein catheterization system is characterized by comprising an operation table (1), a clamping device and an angle adjusting mechanism; the top of the operating platform (1) is provided with a groove (2), and the clamping device is arranged in the groove (2);
the clamping device comprises a first arc-shaped claw (3) and a second arc-shaped claw (4); one side of the first arc-shaped claw (4) is fixedly provided with a hinged shaft (22) along the axial direction, and two ends of the hinged shaft (22) are rotatably connected with two ends of the groove (2) through bearings; one side of the second arc-shaped claw (4) is hinged with the hinge shaft (22), and the arc surfaces of the first arc-shaped claw (3) and the second arc-shaped claw (4) are opposite; a plurality of clamping teeth (5) are uniformly arranged on one side, opposite to the first arc-shaped claw (3) and the second arc-shaped claw (4), along the length direction; a mouse head limiting net (7) and a mouse tail limiting plate (8) are inserted between the two clamping teeth (5), a cavity for accommodating a laboratory mouse is formed between the mouse head limiting net (7) and the mouse tail limiting plate (8), and an outlet for allowing a mouse tail to penetrate out is formed in the mouse tail limiting plate (8);
one end of the first arc-shaped claw (3) and one end of the second arc-shaped claw (4) are provided with clamping pieces for adjusting the opening degree;
a square groove is formed in one end of the operating table (1), and the angle adjusting mechanism is arranged at the bottom of the square groove and used for adjusting the clamping device to rotate in the groove (2);
the top of the operating platform (1) is provided with a tail clamp (10), and the tail clamp (10) is positioned at one end of the groove (2) and is fixed through a fixing block (9); a heating plate (12) is arranged below the tail clamp (10); the top of the operating platform (1) is provided with a controller, and the heating plate (15) is electrically connected with the controller.
2. The tail vein catheter system according to claim 1, wherein the clamping member comprises a fixing plate (6) rotatably connected with one end of the second arc-shaped claw (4); a plurality of clamping joints (21) are uniformly arranged along the length direction of the fixing plate (6); a clamping groove is formed in one end of the first arc-shaped claw (3), and any one of the clamping heads (21) is matched with the clamping groove.
3. The tail vein catheter system according to claim 1, wherein the angle adjusting mechanism comprises a handle (13) and a limiting rod fixedly connected with the handle (13) and arranged side by side; the handle (13) is arranged in the square groove, and the hinge shaft (22) penetrates through one end of the groove (2) and is fixedly connected with the handle (13); the limiting rod comprises a first sleeve (14) and a sleeve rod (15) arranged in the first sleeve (14); the loop bar (15) is connected with the first sleeve (14) through a spring, and the first sleeve (14) is fixedly connected with the handle (13); one end of the operating platform (1) surrounds the handle (13) and is uniformly provided with a plurality of jacks (16), and the tail end of the loop bar (15) is matched with any one jack (16).
4. The tail vein catheter system according to claim 1, wherein the mouse head limiting net (7) and the mouse tail limiting board (8) are respectively provided with a limiting board at the upper end and a baffle and a limiting net at the lower end which are respectively matched with the cavity.
5. The caudal vein catheterization system according to claim 1, wherein one end of the top surface of the console (1) is inclined downwards, and the included angle between the top surface of the console (1) and the bottom surface of the console (1) is 10-30 °.
6. The caudal vein catheterization system according to claim 1, characterized in that a longitudinal support bar (19) is arranged on the side wall of the operation table (1), and a transverse support bar (20) is fixedly arranged at the end of the longitudinal support bar (19); a second sleeve (18) is sleeved outside the transverse supporting rod (20), a plurality of threaded holes are formed in the transverse supporting rod (20) along the length direction, and a plurality of through holes matched with the threaded holes are formed in the second sleeve (18) along the length direction; any one through hole is connected with the threaded hole through a bolt, and a lighting lamp (17) is installed at the tail end of the second sleeve (18); the top surface of the operating platform (1) is provided with a placing groove (11) for placing the magnifier.
7. The caudal vein catheterization system according to claim 1, wherein a placing rack for placing a mouse head limiting net (7) and a mouse tail limiting plate (8) is arranged on the side wall of the operating platform (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010575734.8A CN111631838B (en) | 2020-06-22 | 2020-06-22 | Tail vein catheter system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010575734.8A CN111631838B (en) | 2020-06-22 | 2020-06-22 | Tail vein catheter system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN111631838A true CN111631838A (en) | 2020-09-08 |
| CN111631838B CN111631838B (en) | 2022-07-19 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010575734.8A Active CN111631838B (en) | 2020-06-22 | 2020-06-22 | Tail vein catheter system |
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| Country | Link |
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| CN (1) | CN111631838B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112076814A (en) * | 2020-10-23 | 2020-12-15 | 漯河医学高等专科学校 | Traditional chinese medicine pharmacology laboratory bench |
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| CN108553198A (en) * | 2018-05-09 | 2018-09-21 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | Caudal vein joint intraperitoneal injection fixing device |
| CN208770057U (en) * | 2018-05-24 | 2019-04-23 | 天晴干细胞股份有限公司 | A kind of experimental mouse capture fixator |
| CN208851692U (en) * | 2018-03-30 | 2019-05-14 | 中国人民解放军总医院 | A kind of mouse tail vein injection platform of efficient stable |
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2020
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| CN101584609A (en) * | 2009-06-26 | 2009-11-25 | 河南中医学院 | Mouse holder specialized for experiment |
| CN105559826A (en) * | 2015-12-24 | 2016-05-11 | 温州医科大学附属第二医院 | Device for conveniently fixing mouse body in ultrasonic examination |
| CN205831950U (en) * | 2016-05-13 | 2016-12-28 | 浙江省医学科学院 | A kind of mouse tail vein fast injection auxiliary device |
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| Publication number | Publication date |
|---|---|
| CN111631838B (en) | 2022-07-19 |
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