CN111631732A - System and method for synchronously monitoring muscle tissue blood oxygen parameter and skin surface pressure - Google Patents

System and method for synchronously monitoring muscle tissue blood oxygen parameter and skin surface pressure Download PDF

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CN111631732A
CN111631732A CN202010393381.XA CN202010393381A CN111631732A CN 111631732 A CN111631732 A CN 111631732A CN 202010393381 A CN202010393381 A CN 202010393381A CN 111631732 A CN111631732 A CN 111631732A
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pressure
blood oxygen
muscle
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human body
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张腾宇
李增勇
樊瑜波
吕泽平
李文昊
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National Research Center for Rehabilitation Technical Aids
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/447Skin evaluation, e.g. for skin disorder diagnosis specially adapted for aiding the prevention of ulcer or pressure sore development, i.e. before the ulcer or sore has developed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/746Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01LMEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
    • G01L1/00Measuring force or stress, in general

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Abstract

The invention provides a system and a method for synchronously monitoring a muscle tissue blood oxygen parameter and skin surface pressure. The system comprises: the muscle oxygen level and pressure synchronous acquisition module is used for synchronously acquiring the blood oxygen parameters of local muscle tissues of the human body and the pressure values of the skin surfaces of the corresponding parts; the data analysis module is used for receiving the blood oxygen parameters of local muscle tissues of the human body and the pressure values of the skin surfaces of the corresponding parts transmitted from the muscle oxygen level and pressure synchronous acquisition module, analyzing the mapping relation between the blood oxygen parameters of the local muscle tissues and the pressure values, and setting safe pressure threshold values for maintaining normal microcirculation of the muscle tissues at different parts of the human body; the pressure real-time monitoring module is used for monitoring the pressure values of all areas of contact interfaces of different parts of a human body and other objects in real time; and the alarm module is used for giving an alarm prompt when the pressure real-time monitoring module detects that the pressure value is greater than the safe pressure threshold value. The invention can optimize the interface design of the assistive device and prevent skin problems such as pressure sores and the like.

Description

System and method for synchronously monitoring muscle tissue blood oxygen parameter and skin surface pressure
Technical Field
The invention relates to the field of biological signal detection, in particular to a system and a method for synchronously monitoring a muscle tissue blood oxygen parameter and skin surface pressure.
Background
Some elderly people who lie in bed or sit in a wheelchair for a long time due to limb movement dysfunction and disabled people wearing artificial limbs contact with accessories such as beds, wheelchairs and artificial limb receiving cavities for a long time and are subjected to high pressure, so that skin problems such as pressure sores, damages, dermatitis and the like are easily generated at the contact part of the skin and the accessories.
When the auxiliary tool is designed, the local pressure is prevented from being overlarge by optimizing the interface design of the auxiliary tool, and the problems can be prevented or reduced to a certain extent. In the prior patent applications of pressure sore prevention, such as 'an intelligent pressure sore prevention protective clothing for neurology' (CN201910511502.3) 'a pressure sore prevention cushion with a pressure alarm function' (CN201920316996.5) 'a pressure sore prevention shorts' (CN201910450750.1) and the like, pressure sensors are used for monitoring the pressure of a pressed part, and the aim of reducing local pressure is achieved through structural design.
However, the pressure sore protection technology in the prior art is lack of physiological parameter monitoring reflecting the state of skin muscle tissue, and cannot establish a quantitative relation between the pressure value and the skin tissue injury, namely, it is uncertain what pressure value causes tissue microcirculation disturbance, thereby causing skin problems.
Disclosure of Invention
Based on the above problems, an object of the present invention is to provide a system and a method for synchronously monitoring blood oxygen parameter of muscle tissue and skin surface pressure, which are used for synchronously testing the long-term contact interface pressure between a human body and an accessory and the blood oxygen parameter of skin muscle tissue, establishing a mapping relationship between local tissue blood oxygen parameter and pressure change, obtaining safe pressure thresholds of muscle tissues at different positions, and alarming when detecting that the local pressure is too high. On one hand, the method and the system can be used for optimizing the design of the accessory interface; on the other hand, the auxiliary tool can be used for monitoring and preventing skin problems such as pressure sores and the like.
One aspect of the present invention provides a system for simultaneously monitoring a muscle tissue blood oxygenation parameter and a skin surface pressure, the system comprising:
the muscle oxygen level and pressure synchronous acquisition module is used for synchronously acquiring the blood oxygen parameters of local muscle tissues of the human body and the pressure values of the skin surfaces of the corresponding parts;
the data analysis module is used for receiving the blood oxygen parameters of local muscle tissues of the human body and the pressure values of the skin surfaces of the corresponding parts transmitted from the muscle oxygen level and pressure synchronous acquisition module, analyzing the mapping relation between the blood oxygen parameters of the local muscle tissues and the pressure values, and setting safe pressure threshold values for maintaining normal microcirculation of the muscle tissues at different parts of the human body;
the pressure real-time monitoring module is used for monitoring the pressure values of all areas of contact interfaces of different parts of a human body and other objects in real time; and
and the alarm module is used for giving an alarm prompt when the pressure real-time monitoring module detects that the pressure value is greater than the safety pressure threshold value provided by the data analysis module.
According to one embodiment, the muscle oxygen level and pressure synchronous acquisition module comprises muscle oxygen level and pressure synchronous detection devices and a data transmission device, wherein the muscle oxygen level and pressure synchronous detection devices are used for synchronously detecting the blood oxygen and the pressure level of the muscle tissue at the same part of the human body, and the data transmission device is used for transmitting the detected blood oxygen and the pressure level of the muscle tissue at the same part of the human body to the data analysis module.
According to one embodiment, the muscle oxygen level and pressure synchronization detection device comprises a near-infrared light source, a probe for receiving near-infrared light emitted by the near-infrared light source, and a pressure sensor.
According to one embodiment, the data analysis module includes a wavelet change processing module, a wavelet magnitude processing module, a blood oxygen pressure correspondence module, and a threshold extraction module.
In one embodiment, the wavelet transformation processing module is configured to perform continuous wavelet transformation on the detected blood oxygen level of the muscle tissue and calculate a wavelet amplitude matrix, the wavelet amplitude processing module is configured to extract amplitude parameters of the blood oxygen parameter content of the muscle tissue in different frequency bands, the blood oxygen pressure correspondence module is configured to establish a mapping relationship between the blood oxygen parameter of the muscle tissue in different frequency bands and pressure, and the threshold extraction module is configured to set safety pressure thresholds at different parts of the human body according to pressure values corresponding to critical blood oxygen parameters for maintaining normal microcirculation of the muscle tissue.
In one embodiment, the distributed pressure real-time monitoring module comprises a distributed pressure measurement sensor and a data acquisition and analysis system, the distributed pressure measurement sensor monitors the pressure value of each area of the contact interface between the human body and other objects in real time, and the data acquisition and analysis system is used for analyzing the data acquired by the distributed pressure measurement sensor, so that the pressure value distribution of different areas of the measured part can be acquired simultaneously.
Another aspect of the present invention provides a method for simultaneously monitoring a muscle tissue blood oxygen parameter and a skin surface pressure, comprising the steps of:
1) acquiring blood oxygen parameters of local muscle tissues of a human body and pressure values of the skin surfaces of corresponding parts;
2) analyzing the mapping relation between the blood oxygen parameters of local muscle tissues and pressure changes to obtain pressure-blood oxygen parameter relation curves of different parts;
3) extracting a pressure value corresponding to a critical value of a blood oxygen parameter for maintaining normal microcirculation of local muscle tissues as a safe pressure threshold value;
4) setting safety pressure thresholds of different areas, and carrying out real-time distributed pressure monitoring on contact interfaces of the different areas;
5) and alarming when the local pressure is detected to be higher than the safe pressure threshold value.
According to one embodiment, the muscle tissue blood oxygen parameters described in step 1) include, but are not limited to, oxyhemoglobin concentration, reduced hemoglobin concentration, total hemoglobin concentration change, and blood oxygen saturation.
According to another embodiment, the blood oxygen parameters causing the microcirculatory disturbance of the local musculature in step 3) include a local tissue blood oxygen saturation of less than 60%.
The invention also provides a system for synchronous muscle oxygen and pressure monitoring, which comprises: the device comprises a muscle oxygen and pressure synchronous acquisition module, a data analysis module, a distributed pressure real-time monitoring module and an alarm module.
The muscle oxygen and pressure synchronous acquisition module comprises a flexible sensor with the function of synchronously detecting the blood oxygen and the pressure of the muscle tissue at the same part and a data acquisition circuit, and is used for synchronously acquiring the blood oxygen parameters of the local muscle tissue of the human body and the pressure value of the skin surface of the corresponding part.
Specifically, the flexible sensor with the function of synchronously detecting the blood oxygen and the pressure of the muscular tissue at the same part comprises a light source emitting near infrared light, two probes receiving the near infrared light and a pressure sensor, wherein the light source, the two probes receiving the near infrared light and the pressure sensor are embedded on a flexible sheet, the light source and the probes are linearly arranged according to a certain distance, and the pressure sensor is arranged between the light source and the probes.
According to one embodiment of the present invention, the distances between the near infrared light source and the two probes are 20mm and 30mm, respectively, and the near infrared spectrum technology of dual wavelengths (760nm and 850nm) and dual detectors is selected to detect the local muscle tissue blood oxygen parameters. Further, the detected local muscle tissue blood oxygen parameters include oxyhemoglobin concentration, reduced hemoglobin concentration, total hemoglobin concentration variation and local blood oxygen saturation.
And the data analysis module is used for analyzing the mapping relation between the local muscle tissue blood oxygen parameter and the pressure value and setting the safe pressure threshold values of different parts of the human body according to the pressure values corresponding to the critical blood oxygen parameter for maintaining normal microcirculation of the muscle tissue.
According to a specific embodiment of the present invention, the data analysis module specifically includes a wavelet transformation processing module, configured to perform continuous wavelet transformation on the muscle tissue blood oxygen parameter content signals detected by the near infrared spectrum myooxygen detection device to obtain a wavelet coefficient matrix corresponding to each signal, and then perform modulo operation on the wavelet coefficient matrix to obtain a wavelet amplitude matrix; the wavelet amplitude processing module is used for extracting amplitude parameters of the content of the muscle tissue blood oxygen parameters in different frequency bands, and the frequency band ranges are respectively as follows: I. 0.005-0.02 Hz; II. 0.02-0.06 Hz; III, 0.06-0.15 Hz; IV, 0.15-0.4 Hz; and V, 0.4-2Hz, which respectively reflect endothelial activity related to metabolism, neurogenic activity acting on blood vessel walls, intrinsic myogenic activity of blood vessel smooth muscles, respiration and heart rate activity; the blood oxygen pressure corresponding module is used for establishing a mapping relation between the blood oxygen parameters and the pressures of the muscle tissues in different frequency bands; and the threshold extraction module is used for setting safe pressure thresholds of different parts of the human body according to the pressure values corresponding to the critical blood oxygen parameters for maintaining normal microcirculation of the muscle tissues.
The distributed pressure real-time monitoring module comprises a distributed pressure measurement flexible sensor and a data acquisition and analysis system and is used for monitoring the pressure value of each area of the contact interface of the human body and other objects in real time. Specifically, the distributed pressure measurement flexible sensor comprises a plurality of pressure detection units which are densely distributed and arranged according to a certain rule.
And the alarm module is used for carrying out alarm prompt in the forms of sound, images, characters and the like when detecting that the local pressure is greater than the safety pressure threshold value.
Another aspect of the invention provides a method for simultaneous muscle oxygen and pressure monitoring, the method comprising the steps of:
1) applying variable pressure to different body parts of a user respectively, and synchronously monitoring the blood oxygen parameters and pressure values of muscle tissues of different parts;
2) analyzing the mapping relation between the blood oxygen parameters of local muscle tissues and the pressure change to obtain corresponding relation curves of the pressures and the blood oxygen parameters of different parts;
3) extracting a pressure value corresponding to a critical value of a blood oxygen parameter for maintaining normal microcirculation of local muscle tissues as a safe pressure threshold value;
4) setting safety pressure thresholds of different areas of a human body contact interface, and carrying out real-time distributed pressure monitoring on the contact interface;
5) and alarming when the local pressure is detected to be higher than the safe pressure threshold value.
Specifically, the muscle tissue blood oxygen parameters in step 1) include, but are not limited to, oxyhemoglobin concentration, reduced hemoglobin concentration, total hemoglobin concentration variation, and blood oxygen saturation.
According to a specific embodiment of the present invention, the pressure applied in step 1) may be a pressure value that varies discontinuously, such as: the pressure values of 10KPa, 20KPa and 30KPa are respectively applied to each part, the pressure value is linearly increased in the pressurizing process, and the change conditions of the blood oxygen parameter and the pressure value in the pressurizing process are synchronously detected. Applying pressure for 10 minutes at each pressure value, and synchronously detecting the blood oxygen parameter and the pressure value. And the pressure value is linearly reduced in the process of releasing the pressure, the change conditions of the blood oxygen parameter and the pressure value in the pressure reduction process are synchronously detected, and the blood oxygen parameter is continuously detected for 10 minutes after the pressure is completely released.
According to an embodiment of the present invention, the analyzing the mapping relationship between the local muscle tissue blood oxygen parameter and the pressure variation in step 2) specifically includes the following steps:
performing continuous wavelet transformation on the muscle tissue blood oxygen parameter content signals to obtain a wavelet coefficient matrix corresponding to each signal, and then performing modulo operation on the wavelet coefficient matrix to obtain a wavelet amplitude matrix;
extracting the amplitude parameter of the muscle tissue blood oxygen parameter content of different frequency bands, wherein the frequency band ranges are respectively as follows: I. 0.005-0.02 Hz; II. 0.02-0.06 Hz; III, 0.06-0.15 Hz; IV, 0.15-0.4 Hz; and V, 0.4-2Hz, which respectively reflect endothelial activity related to metabolism, neurogenic activity acting on blood vessel walls, intrinsic myogenic activity of blood vessel smooth muscles, respiration and heart rate activity;
and establishing a mapping relation between the blood oxygen parameters of the muscle tissues in different frequency bands and the pressure.
According to an embodiment of the present invention, the blood oxygen parameter threshold value for maintaining normal microcirculation of local musculature in step 3) is obtained according to data of a pre-performed batch clinical test, such as: the critical value of the blood oxygen saturation of the musculature of the sacral tail is 60 percent, and pressure sores are easily caused when the critical value is lower than 60 percent.
The invention has the beneficial effects that: by utilizing the system and the method, the pressure of the long-term contact interface of the human body and the assistive device and the blood oxygen parameter of the skin muscle tissue can be synchronously tested, the mapping relation between the local tissue blood oxygen parameter and the pressure change is established, and the safe pressure threshold values of the muscle tissues at different positions are obtained according to the relation. The muscle oxygen parameter capable of reflecting the physiological state of the skin muscle tissue is added, and the pressure safety threshold values are respectively set for different users and different parts, so that the safety pressure threshold value determined by the method is more scientific and accurate. The method and the system can be used for establishing the mapping relation between the pressure of the long-term contact interface of the human body and the assistive device and the blood oxygen parameters of the muscle tissues at different positions, and carrying out pressure monitoring and alarming according to the relation, thereby optimizing the design of the assistive device interface on one hand; on the other hand, the auxiliary tool can be used for monitoring and preventing skin problems such as pressure sores and the like.
The foregoing summary is provided for the purpose of description only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features of the present invention will be readily apparent by reference to the drawings and following detailed description.
Drawings
In the drawings, like reference numerals refer to the same or similar parts or elements throughout the several views unless otherwise specified. The figures are not necessarily to scale. It is appreciated that these drawings depict only some embodiments in accordance with the disclosure and are therefore not to be considered limiting of its scope.
FIG. 1 is a general block diagram of a system for simultaneously monitoring a muscle tissue blood oxygenation parameter and a skin surface pressure in accordance with an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a flexible sensor with synchronous measurement of blood oxygen and pressure in the same muscle tissue of the monitoring system for synchronous monitoring of muscle oxygen and pressure shown in FIG. 1;
fig. 3 is a flowchart of a monitoring method for simultaneously monitoring muscle oxygen and muscle pressure according to an embodiment of the present invention.
Detailed Description
In the following, only certain exemplary embodiments are briefly described. As those skilled in the art will recognize, the described embodiments may be modified in various different ways, all without departing from the spirit or scope of the present invention. Accordingly, the drawings and description are to be regarded as illustrative in nature, and not as restrictive.
As shown in FIG. 1, the system for synchronous muscle oxygen and pressure monitoring of the present invention generally comprises four parts, namely a muscle oxygen and pressure synchronous acquisition module 11, a data analysis module 12, a distributed pressure real-time monitoring module 13 and an alarm module 14.
The muscle oxygen and pressure synchronous acquisition module 11 comprises a flexible sensor 11A (namely, a muscle oxygen level and pressure synchronous detection device) and a data acquisition circuit 11B (namely, a data transmission device) which have the same part muscle tissue blood oxygen and pressure synchronous detection function and are used for synchronously acquiring the local muscle tissue blood oxygen parameters of the human body and the pressure values of the skin surfaces of the corresponding parts. The detected blood oxygen parameters of the local muscle tissue comprise oxyhemoglobin concentration, reduced hemoglobin concentration, total hemoglobin concentration variation and local blood oxygen saturation.
Fig. 2 shows a flexible sensor (myooxygen level and pressure synchronous detection device) with the same muscle tissue blood oxygen and pressure synchronous detection function, which comprises a light source 21 emitting near infrared light, probes 22A and 22B receiving the near infrared light emitted by the light source 21, and a pressure sensor 23, all of which are embedded on a flexible sheet 24.
In fig. 2, the light source 21 and the probes 22A and 22B are arranged in a linear manner, the distances between the near-infrared light source 21 and the two probes (22A and 22B) are respectively 20mm and 30mm, and the two-wavelength (760nm and 850nm) and dual-detector near-infrared spectroscopy are selected to detect the local muscle tissue blood oxygen parameters. A pressure sensor 23 is disposed between the light source 21 and the probe 22A for detecting a pressure value at the same location as the acquired muscle tissue blood oxygenation parameter.
However, the present invention is not limited thereto, and for example, the distances between the near-infrared light source 21 and the two probes (22A and 22B) are 30mm and 40mm, respectively.
The data analysis module 12 is configured to receive the blood oxygen parameter of the local muscle tissue of the human body and the pressure value of the skin surface of the corresponding portion transmitted from the muscle oxygen level and pressure synchronous acquisition module, analyze a mapping relationship between the blood oxygen parameter of the local muscle tissue and the pressure value, and set the safety pressure thresholds of different portions of the human body according to the pressure value corresponding to the critical blood oxygen parameter for maintaining normal microcirculation of the muscle tissue.
As shown in fig. 1, data analysis module 12 may include a wavelet change processing module 12A, a wavelet magnitude processing module 12B, a blood oxygen pressure correspondence module 12C, and a threshold extraction module 12D.
The wavelet transformation processing module 12A is configured to perform continuous wavelet transformation on the muscle tissue blood oxygen parameter content signals detected by the near infrared spectrum muscle oxygen detection device to obtain a wavelet coefficient matrix corresponding to each signal, and then perform modulo operation on the wavelet coefficient matrix to obtain a wavelet amplitude matrix.
The wavelet amplitude processing module 12B is configured to extract amplitude parameters of the content of the muscle tissue blood oxygen parameter in different frequency bands, where the frequency band ranges are: I. 0.005-0.02 Hz; II. 0.02-0.06 Hz; III, 0.06-0.15 Hz; IV, 0.15-0.4 Hz; and V, 0.4-2Hz, respectively, reflect metabolic-related endothelial activity, neurogenic activity acting on the vessel wall, intrinsic myogenic activity of the vascular smooth muscle, respiration, and heart rate activity.
The blood oxygen pressure corresponding module 12C is used for establishing a mapping relationship between the blood oxygen parameters and the pressures of the muscle tissues in different frequency bands.
The threshold extraction module 12D is configured to set safe pressure thresholds at different parts of the human body according to pressure values corresponding to critical blood oxygen parameters for maintaining normal microcirculation of muscle tissues.
As shown in fig. 1, the distributed pressure real-time monitoring module 13 includes a distributed pressure measurement flexible sensor 13A and a data acquisition and analysis system 13B, the distributed pressure measurement sensor is used for monitoring pressure values of various areas of contact interfaces between a human body and other objects in real time, and the data acquisition and analysis system is used for analyzing data acquired by the distributed pressure measurement sensor. Specifically, the distributed pressure measurement flexible sensor comprises a plurality of pressure detection units which are densely distributed and arranged according to a certain rule, and can simultaneously acquire pressure value distribution of different areas of a measured part.
The alarm module 14 may include a speaker, a human-computer interface, etc. and is configured to perform an alarm prompt in the form of sound, image, text, etc. when detecting that the local pressure is greater than the safety pressure threshold.
As shown in FIG. 3, the method for synchronous muscle oxygen and pressure monitoring of the present invention comprises the following steps:
s1: applying variable pressure to different body parts of the user respectively, and synchronously monitoring the blood oxygen parameters and the pressure values of muscle tissues at different parts.
Wherein: the monitored muscle tissue blood oxygen parameters comprise oxyhemoglobin concentration, reduced hemoglobin concentration, total hemoglobin concentration variation, blood oxygen saturation and the like.
The part applying pressure is the main contact part of the human body and the assistive device, such as: sacrococcygeal region of long-term bedridden person, ischial region of long-term wheelchair sitting person, and stump region of artificial limb wearer. Each part is divided into a plurality of areas.
The process of applying pressure is: pressure is respectively exerted on each area of the main contact part of the user, and the exerted pressure values comprise different levels such as 10KPa, 20KPa, 30KPa and the like. The pressure value is increased linearly in the pressurizing process, and the change conditions of the blood oxygen parameter and the pressure value in the pressurizing process are synchronously detected. Applying pressure for 10 minutes at each pressure value, and synchronously detecting the blood oxygen parameter and the pressure value. And the pressure value is linearly reduced in the process of releasing the pressure, the change conditions of the blood oxygen parameter and the pressure value in the pressure reduction process are synchronously detected, and the blood oxygen parameter is continuously detected for 10 minutes after the pressure is completely released.
S2: and analyzing the mapping relation between the blood oxygen parameters of the local muscle tissues and the pressure change to obtain corresponding relation curves of the pressures and the blood oxygen parameters of different parts. The method specifically comprises the following steps:
and performing continuous wavelet transformation on the muscle tissue blood oxygen parameter content signals to obtain a wavelet coefficient matrix corresponding to each signal, performing modulo operation on the wavelet coefficient matrix to obtain a wavelet amplitude matrix, and obtaining the fluctuation of the muscle tissue blood oxygen signals in the range of five frequency bands.
Specifically, the five frequency bins are respectively: I. 0.005-0.02 Hz; II. 0.02-0.06 Hz; III, 0.06-0.15 Hz; IV, 0.15-0.4 Hz; and V, 0.4-2Hz, respectively, in response to metabolic-related endothelial activity, neurogenic activity acting on the vessel wall, intrinsic myogenic activity of the vascular smooth muscle, respiration, and heart rate activity.
And averaging the obtained wavelet transformation result in a frequency band to obtain the amplitude-frequency characteristic of the signal, wherein the amplitude result reflects the power of the original blood oxygen signal in a frequency domain to describe the activity degree of the measurement region.
And establishing a mapping relation between the blood oxygen parameters of the muscle tissues in different frequency bands and the pressure to obtain corresponding relation curves of the pressure and the blood oxygen parameters of different parts.
Specifically, as the pressure is increased and the pressure application time is increased, the oxyhemoglobin concentration and the reduced hemoglobin concentration show responses with different degrees, the amount of the reduction of the oxyhemoglobin concentration is larger than that of the reduction of the reduced hemoglobin concentration, the total hemoglobin concentration is the sum of the oxyhemoglobin concentration and the reduced hemoglobin concentration, so that the degree of the change is larger, the blood oxygen saturation is obviously reduced, blood in tissues is reduced or stopped, local blood supply is affected, the oxygen content in blood is reduced, muscle tissues have metabolic failure, and under the continuous action of the pressure, all the tissues generate corresponding degenerative changes, such as congestion, edema, degeneration, bleeding, inflammatory cell aggregation, dermal necrosis and the like, so that pressure sores are caused.
S3: and extracting a pressure value corresponding to the critical value of the blood oxygen parameter for maintaining the normal microcirculation of the local muscle tissue as a safe pressure threshold value.
Wherein, the critical value of blood oxygen parameter for maintaining normal microcirculation of local muscle tissue is obtained according to the data of the batch clinical test performed in advance. Two specific examples are given here.
The first embodiment: according to the results of clinical comparison research on the blood oxygen saturation of the sacral tail musculature of the long-term bedridden people in the pressure sore group and the non-pressure sore group in the early period, the blood oxygen saturation of the sacral tail musculature is lower than 60 percent, so that pressure sore is easily caused, and the pressure value corresponding to the blood oxygen saturation of 60 percent is used as the safe pressure threshold value of the sacral tail.
Second embodiment: according to the change condition of the muscle tissue blood oxygen saturation parameter of the frequency band of 0.005-0.02Hz under different pressure values after wavelet change, when the pressure value of a certain part reaches N, the blood oxygen saturation of the frequency band is obviously reduced, which shows that the muscle tissue metabolic activity is obviously reduced under the pressure value, and microcirculation disturbance is easily caused, therefore, N is set as the safe pressure threshold value of the part.
S4: setting safe pressure thresholds of different areas of a human body contact interface, and carrying out real-time distributed pressure monitoring on the contact interface.
S5: and alarming when the local pressure is detected to be higher than the safe pressure threshold value.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (9)

1. A system for simultaneously monitoring a muscle tissue blood oxygen parameter and a skin surface pressure, comprising:
the muscle oxygen level and pressure synchronous acquisition module is used for synchronously acquiring the blood oxygen parameters of local muscle tissues of the human body and the pressure values of the skin surfaces of the corresponding parts;
the data analysis module is used for receiving the blood oxygen parameters of local muscle tissues of the human body and the pressure values of the skin surfaces of the corresponding parts transmitted from the muscle oxygen level and pressure synchronous acquisition module, analyzing the mapping relation between the blood oxygen parameters of the local muscle tissues and the pressure values, and setting safe pressure threshold values for maintaining normal microcirculation of the muscle tissues at different parts of the human body;
the pressure real-time monitoring module is used for monitoring the pressure values of all areas of contact interfaces of different parts of a human body and other objects in real time; and
and the alarm module is used for giving an alarm prompt when the pressure real-time monitoring module detects that the pressure value is greater than the safety pressure threshold value provided by the data analysis module.
2. The system of claim 1, wherein the muscle oxygen level and pressure synchronous acquisition module comprises muscle oxygen level and pressure synchronous detection means for synchronously detecting blood oxygen and pressure levels of muscle tissues of the same part of the human body and data transmission means for transmitting the detected blood oxygen and pressure levels of the muscle tissues of the same part of the human body to the data analysis module.
3. The system of claim 2, wherein the muscle oxygen level and pressure synchronization detection device comprises a near-infrared light source, a probe that receives near-infrared light emitted by the near-infrared light source, and a pressure sensor.
4. The system of claim 1, wherein the data analysis module comprises a wavelet change processing module, a wavelet magnitude processing module, a blood oxygen pressure correspondence module, and a threshold extraction module.
5. The system of claim 4, wherein the wavelet transform processing module is configured to perform continuous wavelet transform on the detected blood oxygen level of the muscle tissue and calculate a wavelet amplitude matrix, the wavelet amplitude processing module is configured to extract amplitude parameters of the blood oxygen parameter content of the muscle tissue in different frequency bands, the blood oxygen pressure mapping module is configured to establish a mapping relationship between the blood oxygen parameters of the muscle tissue in different frequency bands and the pressure, and the threshold value extracting module is configured to set the safety pressure threshold values of different parts of the human body according to the pressure values corresponding to the critical blood oxygen parameters for maintaining normal microcirculation of the muscle tissue.
6. The system of claim 1, wherein the distributed pressure real-time monitoring module comprises a distributed pressure measurement sensor and a data acquisition and analysis system, the distributed pressure measurement sensor is used for monitoring the pressure value of each area of the contact interface between the human body and other objects in real time, and the data acquisition and analysis system is used for analyzing the data acquired by the distributed pressure measurement sensor, so that the pressure value distribution of different areas of the measured part can be acquired simultaneously.
7. A method for simultaneously monitoring a muscle tissue blood oxygen parameter and a skin surface pressure, comprising the steps of:
1) acquiring blood oxygen parameters of local muscle tissues of a human body and pressure values of the skin surfaces of corresponding parts;
2) analyzing the mapping relation between the blood oxygen parameters of local muscle tissues of the human body and the pressure change of the skin surface of the corresponding part to obtain pressure-blood oxygen parameter relation curves of different parts;
3) extracting a pressure value corresponding to a critical value of a blood oxygen parameter for maintaining normal microcirculation of local muscle tissues as a safe pressure threshold value;
4) setting safety pressure thresholds of different areas, and carrying out real-time distributed pressure monitoring on contact interfaces of the different areas;
5) and alarming when the local pressure is detected to be higher than the safe pressure threshold value.
8. The method of claim 7, wherein said muscle tissue blood oxygen parameters of step 1) include, but are not limited to, oxyhemoglobin concentration, reduced hemoglobin concentration, total hemoglobin concentration change and blood oxygen saturation.
9. The method as claimed in claim 8, wherein the blood oxygen parameters causing the local microcirculatory disturbance of the musculature in step 3) include local tissue blood oxygen saturation of less than 60%.
CN202010393381.XA 2020-05-11 2020-05-11 System and method for synchronously monitoring muscle tissue blood oxygen parameter and skin surface pressure Pending CN111631732A (en)

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