CN111628741A - Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker - Google Patents
Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker Download PDFInfo
- Publication number
- CN111628741A CN111628741A CN202010435648.7A CN202010435648A CN111628741A CN 111628741 A CN111628741 A CN 111628741A CN 202010435648 A CN202010435648 A CN 202010435648A CN 111628741 A CN111628741 A CN 111628741A
- Authority
- CN
- China
- Prior art keywords
- resistor
- circuit
- electrode
- pacing
- common
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03F—AMPLIFIERS
- H03F3/00—Amplifiers with only discharge tubes or only semiconductor devices as amplifying elements
- H03F3/45—Differential amplifiers
- H03F3/45071—Differential amplifiers with semiconductor devices only
- H03F3/45479—Differential amplifiers with semiconductor devices only characterised by the way of common mode signal rejection
- H03F3/45928—Differential amplifiers with semiconductor devices only characterised by the way of common mode signal rejection using IC blocks as the active amplifying circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/056—Transvascular endocardial electrode systems
- A61N1/0563—Transvascular endocardial electrode systems specially adapted for defibrillation or cardioversion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/37—Monitoring; Protecting
- A61N1/3702—Physiological parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/37—Monitoring; Protecting
- A61N1/3702—Physiological parameters
- A61N1/3704—Circuits specially adapted therefor, e.g. for sensitivity control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37512—Pacemakers
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03F—AMPLIFIERS
- H03F1/00—Details of amplifiers with only discharge tubes, only semiconductor devices or only unspecified devices as amplifying elements
- H03F1/02—Modifications of amplifiers to raise the efficiency, e.g. gliding Class A stages, use of an auxiliary oscillation
- H03F1/0205—Modifications of amplifiers to raise the efficiency, e.g. gliding Class A stages, use of an auxiliary oscillation in transistor amplifiers
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03F—AMPLIFIERS
- H03F3/00—Amplifiers with only discharge tubes or only semiconductor devices as amplifying elements
- H03F3/68—Combinations of amplifiers, e.g. multi-channel amplifiers for stereophonics
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K17/00—Electronic switching or gating, i.e. not by contact-making and –breaking
- H03K17/51—Electronic switching or gating, i.e. not by contact-making and –breaking characterised by the components used
- H03K17/56—Electronic switching or gating, i.e. not by contact-making and –breaking characterised by the components used by the use, as active elements, of semiconductor devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Power Engineering (AREA)
- Vascular Medicine (AREA)
- Electrotherapy Devices (AREA)
Abstract
The utility model belongs to the technical field of medical instrument, a pace-making switching circuit, pace-making auto-change over device and implanted cardiac pacemaker are provided, be connected with first electrode and second electrode through electrocardio acquisition circuit, in order to receive electrocardio acquisition signal, and adopt switch circuit to connect pace-making circuit and first electrode, the second electrode, on-off control signal controls switch circuit's on-off state, thereby control pace pulse signal's output state, thereby integrate pace-making circuit and electrocardio acquisition circuit in same circuit, switch immediately as required, the volume that has solved current pacemaker circuit existence is great, circuit structure ten minutes is complicated, the higher problem of consumption.
Description
Technical Field
The application belongs to the technical field of medical equipment, and particularly relates to a pacing switching circuit, a pacing switching device and an implantable cardiac pacemaker.
Background
The pacemaker can obviously improve the life quality of heart patients, particularly bradycardia patients, and prolong the service life of the patients, and because the pacemaker is an implanted device and needs to be implanted into the body when in use, the basic feeling of the patients is determined by the size of the pacemaker, and the small size can make the patients feel more natural and comfortable. Besides the volume, the medical apparatus implanted into the body has a more important index, namely the service life, namely the power consumption of the pacemaker, and the pacemaker with smaller power consumption has longer service life and can work for longer time under the same energy, so that a patient does not worry about the energy exhaustion of the pacemaker, the risk of implanting the pacemaker again by an operation due to the energy exhaustion is avoided, the fund is saved, and a plurality of problems caused by the operation again are avoided.
However, the existing pacemaker circuit generally sets the pacing circuit and the electrocardio acquisition circuit independently, and has the problems of large volume, very complex circuit structure and high power consumption.
Disclosure of Invention
The application aims to provide a pacing switching circuit, a pacing switching device and an implantable cardiac pacemaker, and aims to solve the problems of large size, very complex circuit structure and high power consumption of the conventional pacemaker circuit.
A first aspect of an embodiment of the present application provides a pacing switching circuit, including:
a first electrode;
a second electrode;
a pacing circuit for providing a pacing pulse signal and a switch control signal;
the switch circuit is respectively connected with the first electrode, the second electrode and the pacing circuit, and is used for receiving the pacing pulse signal and the switch control signal and controlling the output state of the pacing pulse signal according to the switch control signal; and
and the electrocardio acquisition circuit is respectively connected with the first electrode and the second electrode and is used for receiving electrocardio acquisition signals output by the first electrode and the second electrode.
Optionally, the switching circuit includes:
the first switch unit is respectively connected with the pacing circuit and the first electrode, and is used for receiving the pacing pulse signal and the switch control signal and controlling the connection state between the pacing circuit and the first electrode according to the switch control signal;
and the second switch unit is respectively connected with the pacing circuit and the first electrode, and is used for receiving the pacing pulse signal and the switch control signal and controlling the connection state between the pacing circuit and the second electrode according to the switch control signal.
Optionally, the first switch unit is a first transistor, an input end of the first transistor is connected to a pacing pulse signal output end of the pacing circuit, a control end of the first transistor is connected to a switch control signal output end of the pacing circuit, and an output end of the first transistor is connected to the first electrode.
Optionally, the second switch unit is a second transistor, an input end of the second transistor is connected to a ground end of the pacing circuit, a control end of the second transistor is connected to a switch control signal output end of the pacing circuit, and an output end of the second transistor is connected to the second electrode.
Optionally, the electrocardiograph acquisition circuit includes:
the common-mode signal following unit is respectively connected with the first electrode and the second electrode, and is used for receiving the electrocardio acquisition signals output by the first electrode and the second electrode and generating reference voltage signals according to the electrocardio acquisition signals;
and the common-mode amplification unit is respectively connected with the common-mode signal following unit, the first electrode and the second electrode, and is used for amplifying the electrocardio acquisition signals and carrying out common-mode rejection processing on the electrocardio acquisition signals according to the reference voltage signals.
Optionally, the common-mode signal following unit includes: the circuit comprises a first differential amplifier, a first resistor, a second resistor, a third resistor, a fourth resistor and a fifth resistor;
the first end of the first resistor is connected with the first electrode, the first end of the second resistor is connected with the second electrode, the second end of the first resistor, the second end of the second resistor and the first end of the third resistor are connected together, the second end of the third resistor is connected with the first input end of the first differential amplifier, the second input end of the first differential amplifier, the output end of the first differential amplifier, the first end of the fourth resistor and the first end of the fifth resistor are connected together to form the reference voltage signal output end of the common-mode signal following unit and the common-mode amplifying unit, the second end of the fifth resistor is grounded, and the second end of the fourth resistor is connected with a working power supply.
Optionally, the common mode amplifying unit includes: the second differential amplifier, the third differential amplifier, the fourth differential amplifier, the sixth resistor, the seventh resistor, the eighth resistor, the ninth resistor, the tenth resistor, the eleventh resistor and the twelfth resistor;
the first input end of the second differential amplifier is connected to the first electrode, the first input end of the third differential amplifier is connected to the second electrode, the second input end of the second differential amplifier, the first end of the sixth resistor and the first end of the seventh resistor are connected in common, the second input end of the third differential amplifier, the second end of the seventh resistor and the first end of the eighth resistor are connected in common, the second end of the sixth resistor, the output end of the second differential amplifier and the first end of the tenth resistor are connected in common, the second end of the eighth resistor, the output end of the third differential amplifier and the first end of the ninth resistor are connected in common, the second end of the ninth resistor, the first end of the twelfth resistor and the first input end of the fourth differential amplifier are connected in common, and the second end of the twelfth resistor is connected to the common-mode signal following unit, the second end of the tenth resistor, the first end of the eleventh resistor and the second input end of the fourth differential amplifier are connected in common, and the second end of the eleventh resistor and the output end of the fourth differential amplifier are connected in common to form the output end of the common mode amplifying unit.
Optionally, the pacing switching circuit further includes:
the control circuit is respectively connected with the pacing circuit and the electrocardio acquisition circuit and is used for receiving the electrocardio acquisition signal and sending a control signal to the pacing circuit according to the electrocardio acquisition signal;
wherein the pacing circuit generates the pacing pulse signal and the switch control signal according to the control signal.
The second aspect of the embodiments of the present application also provides a pacing switching device, including the pacing switching circuit according to any one of the above-mentioned items.
The third aspect of the embodiments of the present application further provides an implantable cardiac pacemaker including the pacing switching circuit according to any one of the above-mentioned embodiments.
In the pace-making switching circuit, pace-making switching device and implanted cardiac pacemaker that this application embodiment provided, be connected with first electrode and second electrode through electrocardio acquisition circuit, in order to receive electrocardio acquisition signal, and adopt switch circuit to connect pace-making circuit and first electrode, the second electrode, control switch circuit's on-off state through the on-off control signal, thereby control pace pulse signal's output state, thereby integrate pace-making circuit and electrocardio acquisition circuit in same circuit, switch immediately as required, the volume that has solved current pacemaker circuit existence is great, circuit structure is very complicated, the higher problem of consumption.
Drawings
Fig. 1 is a schematic structural diagram of a pacing switching circuit according to an embodiment of the present application;
fig. 2 is a schematic structural diagram of a pacing switching circuit according to another embodiment of the present application;
FIG. 3 is a schematic structural diagram of an electrical cardiac acquisition circuit according to an embodiment of the present application;
fig. 4 is a schematic structural diagram of a pacing switching circuit according to another embodiment of the present application;
fig. 5 is a schematic structural diagram of a pacing circuit according to an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
In the description of the present application, it is to be understood that the terms "first", "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature.
The first aspect of the embodiment of the present application provides a pacing switching circuit, which includes a first electrode 11, a second electrode 12, a pacing circuit 20, a switching circuit 30, and an electrocardiograph acquisition circuit 40; wherein, the pacing circuit 20 is used for providing a pacing pulse signal and a switch control signal; the switch circuit 30 is respectively connected to the first electrode 11, the second electrode 12 and the pacing circuit 20, and is configured to receive the pacing pulse signal and the switch control signal, and control an output state of the pacing pulse signal according to the switch control signal; the electrocardiogram acquisition circuit 40 is respectively connected to the first electrode 11 and the second electrode 12, and is configured to receive electrocardiogram acquisition signals output by the first electrode 11 and the second electrode 12.
In this embodiment, a first input terminal of the switch circuit 30 is connected to a pacing pulse signal output terminal of the pacing circuit 20, a second input terminal of the switch circuit 30 is connected to a ground terminal of the pacing circuit 20, a first output terminal of the switch circuit 30 is connected to the first electrode 11, and a second output terminal of the switch circuit 30 is connected to the second electrode 12, wherein the switch control signal is used to control a connection state between the first input terminal and the first output terminal and a connection state between the second input terminal and the second output terminal. In a specific application, the switch circuit 30 controls the grounding state of the second electrode 12, so that the electrocardiograph acquisition circuit 40 can be introduced into a differential circuit, and the common-mode rejection ratio of the electrocardiograph acquisition circuit can be increased. For example, in a non-pacing state, the second electrode 12 is disconnected from the ground as an anode electrode, and the second output terminal is in a high-impedance state at this time, and the preamplifier of the electrocardiograph acquisition circuit 40 may adopt a differential circuit, so as to increase the common-mode rejection ratio of the electrocardiograph acquisition circuit 40, where the higher the common-mode rejection ratio is, the stronger the 50Hz power frequency interference rejection capability is, and the better the quality of the acquired electrocardiograph waveform is.
In one embodiment, referring to fig. 2, the switching circuit 30 includes a first switching unit 31 and a second switching unit 32; the first switch unit 31 is connected to the pacing circuit 20 and the first electrode 11, and configured to receive the pacing pulse signal and the switch control signal, and control a connection state between the pacing circuit 20 and the first electrode 11 according to the switch control signal; and a second switch unit 32, connected to the pacing circuit 20 and the first electrode 11, respectively, and configured to receive the pacing pulse signal and the switch control signal, and control a connection state between the pacing circuit 20 and the second electrode 12 according to the switch control signal.
In the present embodiment, the first switch unit 31 is disposed between the pacing circuit 20 and the first electrode 11, the second switch unit 32 is disposed between the pacing circuit 20 and the second electrode 12, and the pacing circuit 20 controls on and off of the first switch unit 31 and the second switch unit 32 by outputting a switch control signal. For example, in a pacing state, the switching circuit 30 is turned on by sending a corresponding switching control signal, thereby sending a pacing pulse signal through the pacing circuit 20 to the second electrode 12.
Furthermore, a switch circuit 30 can be arranged between the electrocardiogram acquisition circuit 40 and the first electrode 11 and the second electrode 12, and the same switch control signal is used for controlling, and only one of the two switch circuits 30 is conducted at the same time, so that the influence of the pacing pulse signal sent in the pacing state on the electrocardiogram acquisition circuit 40 is avoided.
In one embodiment, referring to fig. 2, the first switch unit 31 is a first transistor T1, an input terminal of the first transistor T1 is connected to a pacing pulse signal output terminal of the pacing circuit 20, a control terminal of the first transistor T1 is connected to a switch control signal output terminal of the pacing circuit 20, and an output terminal of the first transistor T1 is connected to the first electrode 11.
In one embodiment, referring to fig. 2, the second switch unit 32 is a second transistor T2, an input terminal of the second transistor T2 is connected to the ground terminal of the pacing circuit 20, a control terminal of the second transistor T2 is connected to the switch control signal output terminal of the pacing circuit 20, and an output terminal of the second transistor T2 is connected to the second electrode 12.
In this embodiment, the pacing switching circuit includes a pacing output state and an electrocardiograph collecting state, when the pacing switching circuit operates in the pacing output state, the first transistor T1 and the second transistor T2 are turned on, the pacing pulse signal is output to the first electrode 11 and the second electrode 12, when the pacing switching circuit operates in the electrocardiograph collecting state, the first transistor T1 and the second transistor T2 are turned off, and the pacing circuit 20 is disconnected from the first electrode 11 and the second electrode 12, so that the normal operation of the electrocardiograph collecting circuit 40 is not affected.
In one embodiment, referring to fig. 3, the electrocardiograph acquisition circuit 40 includes a common-mode signal following unit 41 and a common-mode amplifying unit 42; the common-mode signal following unit 41 is respectively connected with the first electrode 11 and the second electrode 12, and is configured to receive the electrocardiograph acquisition signals output by the first electrode 11 and the second electrode 12, and generate a reference voltage signal according to the electrocardiograph acquisition signals; the common mode amplifying unit 42 is respectively connected to the common mode signal following unit 41, the first electrode 11, and the second electrode 12, and is configured to amplify the electrocardiographic acquisition signal and perform common mode rejection processing on the electrocardiographic acquisition signal according to the reference voltage signal.
In the present embodiment, the amplitude of the common mode signal is reduced by the common mode signal following unit 41, thereby improving the common mode rejection ratio. Specifically, the common mode signal following unit 41 generates a reference voltage signal based on the signals collected by the first electrode 11 and the second electrode 12, and superimposes the reference voltage signal on the reference signal source of the common mode amplifying unit 42, and when the common mode signal changes, the reference voltage signal also changes, thereby indirectly reducing the amplitude of the common mode voltage.
In one embodiment, referring to fig. 3, the common mode signal following unit 41 includes: the circuit comprises a first differential amplifier U1, a first resistor R1, a second resistor R2, a third resistor R3, a fourth resistor R4 and a fifth resistor R5; the first end of the first resistor R1 is connected to the first electrode 11, the first end of the second resistor R2 is connected to the second electrode 12, the second end of the first resistor R1, the second end of the second resistor R2 and the first end of the third resistor R3 are connected in common, the second end of the third resistor R3 is connected to the first input end of the first differential amplifier U1, the second input end of the first differential amplifier U1, the output end of the first differential amplifier U1, the first end of the fourth resistor R4 and the first end of the fifth resistor R5 are connected in common to form the reference voltage signal output end of the common mode signal following unit 41 and the common mode amplifying unit 42, the second end of the fifth resistor R5 is connected to ground, and the second end of the fourth resistor R4 is connected to the working power supply.
In this embodiment, the voltage of the input common-mode signal is between the first resistor R1 and the second resistor R2, and the common-mode voltage is superimposed on the reference signal source of the common-mode amplifying unit 42 of the single power supply after passing through the first differential amplifier U1, and when the common-mode signal changes, the reference voltage signal also changes, thereby indirectly reducing the amplitude of the common-mode voltage.
In one embodiment, referring to fig. 3, the common mode amplifying unit 42 includes: a second differential amplifier U2, a third differential amplifier U3, a fourth differential amplifier U4, a sixth resistor R6, a seventh resistor R7, an eighth resistor R8, a ninth resistor R9, a tenth resistor R10, an eleventh resistor R11, and a twelfth resistor R12; a first input terminal of the second differential amplifier U2 is connected to the first electrode 11, a first input terminal of the third differential amplifier U3 is connected to the second electrode 12, a second input terminal of the second differential amplifier U2, a first terminal of the sixth resistor R6 and a first terminal of the seventh resistor R7 are connected in common, a second input terminal of the third differential amplifier U3, a second terminal of the seventh resistor R7 and a first terminal of the eighth resistor R8 are connected in common, a second terminal of the sixth resistor R6, an output terminal of the second differential amplifier U2 and a first terminal of the tenth resistor R10 are connected in common, a second terminal of the eighth resistor R8, an output terminal of the third differential amplifier U3 and a first terminal of the ninth resistor R9 are connected in common, a second terminal of the ninth resistor R9, a first terminal of the twelfth resistor R12 and a first terminal of the fourth differential amplifier U4 are connected in common, a second end of the twelfth resistor R12 is connected to the common mode signal following unit 41, a second end of the tenth resistor R10, a first end of the eleventh resistor R11, and a second input end of the fourth differential amplifier U4 are commonly connected, and a second end of the eleventh resistor R11 and an output end of the fourth differential amplifier U4 are commonly connected to form an output end of the common mode amplifying unit 42.
In the present embodiment, the reference voltage signal Vref output by the common mode signal following unit 41 is superimposed on the reference voltage source of the first input terminal of the fourth differential amplifier U4, so that the signal of the first input terminal of the fourth differential amplifier U4 varies with the variation of the common mode signal, to indirectly reduce the amplitude of the common mode voltage.
In one embodiment, referring to fig. 4, the pacing switching circuit further comprises: the control circuit 50 is respectively connected with the pacing circuit 20 and the electrocardio acquisition circuit 40, and is used for receiving the electrocardio acquisition signal and sending a control signal to the pacing circuit 20 according to the electrocardio acquisition signal; wherein the pacing circuit 20 generates the pacing pulse signal and the switch control signal according to the control signal.
In this embodiment, when the pacing switching circuit is in the electrocardiographic acquisition state, the control circuit 50 receives the electrocardiographic acquisition signal and analyzes the electrocardiographic acquisition signal, for example, determines whether the electrocardiographic acquisition signal is within the preset threshold range, and if not, the pacing switching circuit is in the pacing output state, and outputs the pacing pulse signal to the heart through the first electrode 11 and the second electrode 12 by outputting the pacing signal to the pacing circuit 20 and outputting the switch control signal to the switching circuit 30, so as to stimulate the heart beat.
In an embodiment, fig. 5 is a schematic circuit diagram of a pacing circuit 20 provided in this embodiment, and referring to fig. 5, the pacing circuit 20 includes: a fifth differential amplifier U5, a sixth differential amplifier U6, a thirteenth resistor R13, a fourteenth resistor R14, a fifteenth resistor R15, and a sixteenth resistor R16; a first end of the thirteenth resistor R13 is connected to the control circuit 50, a second end of the thirteenth resistor R13, a first end of the fifteenth resistor R15, and a second input end of the fifth differential amplifier U5 are commonly connected, a first input end of the fifth differential amplifier U5 is connected to a first end of the fourteenth resistor R14, a second end of the fourteenth resistor R14 is grounded, a power source end of the fifth differential amplifier U5 is connected to the first power source, a ground end of the fifth differential amplifier U5 is connected to the second power source, an output end of the fifth differential amplifier U5, a second end of the fifteenth resistor R15, and a first end of the sixteenth resistor R16 are commonly connected, a second end of the sixteenth resistor R16 is connected to a first input end of the sixth differential amplifier U6, an output end of the sixth differential amplifier U6, and a second input end of the sixth differential amplifier U6 are commonly connected to the switch circuit 30.
In this embodiment, when the pacing switching circuit operates in the pacing output state, the pacing circuit 20 amplifies the pacing output signal sent by the control circuit 50 and outputs a corresponding pacing pulse signal, and the control circuit 50 sends a corresponding switch control signal to control the switch circuit 30 to be turned on, so as to output the pacing pulse signal to the first electrode 11 and the second electrode 12, so as to stimulate the heart.
Further, after the preset time interval, the control circuit 50 sends a corresponding switch control signal to turn off the switch circuit 30, and performs the electrocardiographic signal acquisition on the heart through the electrocardiographic acquisition circuit 40, and if the electrocardiographic signal is within the preset threshold range, the output of the pacing pulse signal is stopped, and at this time, the pacing switching circuit enters the electrocardiographic acquisition state.
In one embodiment, the control circuit 50 is further configured to adjust the operating clock frequency according to the collected cardiac electrical signal to reduce power consumption of the control circuit, and the adjusting the operating clock frequency according to the collected cardiac electrical signal by the control circuit 50 includes:
step 1, the control circuit 50 initializes and reduces the operating frequency to a first preset threshold frequency to enter the sleep mode.
In this embodiment, the control circuit 50 enters the main loop process after initialization, and the first step of the main loop process is to reduce the operating frequency to the first preset threshold frequency, so that the control circuit 50 enters the sleep mode.
When the timing sampling of the electrocardiograph acquisition circuit 40 is interrupted, the control circuit 50 enters a response of interrupting the reading of the electrocardiograph acquisition circuit 40. The response first wakes up the control circuit 50 to enter the working mode, then reads the electrocardiographic data and stores the electrocardiographic data in the buffer, and the sampling number is increased by one, and finally the cycle is exited. After the control circuit 50 is awakened, step 2 of the main loop is performed.
And 2, judging whether the sampling period of the electrocardiosignals is finished, if not, continuing to execute the step 1, and if so, increasing the working frequency of the control circuit 50 to a second preset threshold frequency and storing the acquired electrocardio data into a memory.
In this embodiment, it is mainly determined whether the sampling period of the electrocardiographic signal is finished, if not, step 1 is continuously executed, and if so, step 21 may be executed, that is, the operating frequency of the control circuit 50 is increased to the second preset threshold frequency, and the acquired electrocardiographic data is stored in the memory.
The memory can be a large-capacity flash memory or an sd card (secure digital card).
And 3, judging whether the electrocardiosignals in the acquisition period are abnormal or not according to the electrocardio data, if so, adjusting the clock frequency of the control circuit 50 to be a preset high-frequency, and if not, adjusting the clock frequency of the control circuit 50 to be a preset low-frequency.
In this embodiment, the control circuit 50 may evaluate the electrocardiographic signal based on an electrocardiographic signal evaluation algorithm, and if the electrocardiographic signal is abnormal, a complicated electrocardiographic processing algorithm under a high-frequency clock is used, and if the electrocardiographic signal is normal, a simple electrocardiographic algorithm under a low-frequency clock is used.
In this embodiment, the process of evaluating the quality of the electrocardiographic signal is performed at a low clock frequency by adding a step of evaluating the quality of the electrocardiographic signal. When the quality of the electrocardiosignals is evaluated to be normal, the electrocardiosignals are processed by using a simple electrocardio algorithm with low clock frequency, and when an abnormality is found, the electrocardiosignals are processed by switching to a fussy electrocardio algorithm running under high clock frequency, so that the operation time of the control circuit 50 is reduced, and the power consumption is reduced.
Further, in this embodiment, the control circuit 50 also reduces power consumption by adding a method for controlling the clock frequency, using a high clock frequency for tasks with more computation and storage, using a low clock frequency for tasks with more IO operations, and changing the clock frequency.
Furthermore, if the control circuit 50 determines that the electrocardiographic signal is abnormal, it can drive an alarm module such as an LED lamp or a buzzer to operate to send an alarm signal.
Further, if the control circuit 50 determines that the electrocardiographic signal is abnormal, the switching circuit 30 may be driven to be turned on to control the pacing circuit 20 to output the pacing pulse signal.
The second aspect of the embodiments of the present application also provides a pacing switching device, including the pacing switching circuit according to any one of the above-mentioned items.
The third aspect of the embodiments of the present application further provides an implantable cardiac pacemaker including the pacing switching circuit according to any one of the above-mentioned embodiments.
In the pace-making switching circuit, pace-making switching device and implanted cardiac pacemaker that this application embodiment provided, be connected with first electrode and second electrode through electrocardio acquisition circuit, in order to receive electrocardio acquisition signal, and adopt switch circuit to connect pace-making circuit and first electrode, the second electrode, control switch circuit's on-off state through the on-off control signal, thereby control pace pulse signal's output state, thereby integrate pace-making circuit and electrocardio acquisition circuit in same circuit, switch immediately as required, the volume that has solved current pacemaker circuit existence is great, circuit structure is very complicated, the higher problem of consumption.
The above description is only exemplary of the present application and should not be taken as limiting the present application, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present application should be included in the protection scope of the present application.
Claims (10)
1. A pacing switching circuit, comprising:
a first electrode;
a second electrode;
a pacing circuit for providing a pacing pulse signal and a switch control signal;
the switch circuit is respectively connected with the first electrode, the second electrode and the pacing circuit, and is used for receiving the pacing pulse signal and the switch control signal and controlling the output state of the pacing pulse signal according to the switch control signal; and
and the electrocardio acquisition circuit is respectively connected with the first electrode and the second electrode and is used for receiving electrocardio acquisition signals output by the first electrode and the second electrode.
2. The pacing switching circuit of claim 1, wherein the switching circuit comprises:
the first switch unit is respectively connected with the pacing circuit and the first electrode, and is used for receiving the pacing pulse signal and the switch control signal and controlling the connection state between the pacing circuit and the first electrode according to the switch control signal;
and the second switch unit is respectively connected with the pacing circuit and the first electrode, and is used for receiving the pacing pulse signal and the switch control signal and controlling the connection state between the pacing circuit and the second electrode according to the switch control signal.
3. The pace switching circuit according to claim 2, wherein the first switching unit is a first transistor, an input terminal of the first transistor is connected to a pace pulse signal output terminal of the pace circuit, a control terminal of the first transistor is connected to a switching control signal output terminal of the pace circuit, and an output terminal of the first transistor is connected to the first electrode.
4. The pace switching circuit according to claim 2, wherein the second switching unit is a second transistor, an input terminal of the second transistor is connected to a ground terminal of the pace circuit, a control terminal of the second transistor is connected to a switching control signal output terminal of the pace circuit, and an output terminal of the second transistor is connected to the second electrode.
5. The pacing switching circuit of claim 1, wherein the cardiac electrical acquisition circuit comprises:
the common-mode signal following unit is respectively connected with the first electrode and the second electrode, and is used for receiving the electrocardio acquisition signals output by the first electrode and the second electrode and generating reference voltage signals according to the electrocardio acquisition signals;
and the common-mode amplification unit is respectively connected with the common-mode signal following unit, the first electrode and the second electrode, and is used for amplifying the electrocardio acquisition signals and carrying out common-mode rejection processing on the electrocardio acquisition signals according to the reference voltage signals.
6. The pacing switching circuit of claim 5, wherein the common mode signal following unit comprises: the circuit comprises a first differential amplifier, a first resistor, a second resistor, a third resistor, a fourth resistor and a fifth resistor;
the first end of the first resistor is connected with the first electrode, the first end of the second resistor is connected with the second electrode, the second end of the first resistor, the second end of the second resistor and the first end of the third resistor are connected together, the second end of the third resistor is connected with the first input end of the first differential amplifier, the second input end of the first differential amplifier, the output end of the first differential amplifier, the first end of the fourth resistor and the first end of the fifth resistor are connected together to form the reference voltage signal output end of the common-mode signal following unit and the common-mode amplifying unit, the second end of the fifth resistor is grounded, and the second end of the fourth resistor is connected with a working power supply.
7. The pacing switching circuit of claim 5, wherein the common mode amplification unit comprises: the second differential amplifier, the third differential amplifier, the fourth differential amplifier, the sixth resistor, the seventh resistor, the eighth resistor, the ninth resistor, the tenth resistor, the eleventh resistor and the twelfth resistor;
the first input end of the second differential amplifier is connected to the first electrode, the first input end of the third differential amplifier is connected to the second electrode, the second input end of the second differential amplifier, the first end of the sixth resistor and the first end of the seventh resistor are connected in common, the second input end of the third differential amplifier, the second end of the seventh resistor and the first end of the eighth resistor are connected in common, the second end of the sixth resistor, the output end of the second differential amplifier and the first end of the tenth resistor are connected in common, the second end of the eighth resistor, the output end of the third differential amplifier and the first end of the ninth resistor are connected in common, the second end of the ninth resistor, the first end of the twelfth resistor and the first input end of the fourth differential amplifier are connected in common, and the second end of the twelfth resistor is connected to the common-mode signal following unit, the second end of the tenth resistor, the first end of the eleventh resistor and the second input end of the fourth differential amplifier are connected in common, and the second end of the eleventh resistor and the output end of the fourth differential amplifier are connected in common to form the output end of the common mode amplifying unit.
8. The pacing switching circuit of claim 1, wherein the pacing switching circuit further comprises:
the control circuit is respectively connected with the pacing circuit and the electrocardio acquisition circuit and is used for receiving the electrocardio acquisition signal and sending a control signal to the pacing circuit according to the electrocardio acquisition signal;
wherein the pacing circuit generates the pacing pulse signal and the switch control signal according to the control signal.
9. A pacing switching device comprising a pacing switching circuit according to any one of claims 1-8.
10. An implantable cardiac pacemaker comprising a pacing switching circuit according to any one of claims 1-8.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010435648.7A CN111628741A (en) | 2020-05-21 | 2020-05-21 | Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker |
| PCT/CN2020/139581 WO2021232788A1 (en) | 2020-05-21 | 2020-12-25 | Pacemaking switching circuit, pacemaking switching apparatus, and implantable cardiac pacemaker |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010435648.7A CN111628741A (en) | 2020-05-21 | 2020-05-21 | Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111628741A true CN111628741A (en) | 2020-09-04 |
Family
ID=72272069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010435648.7A Pending CN111628741A (en) | 2020-05-21 | 2020-05-21 | Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN111628741A (en) |
| WO (1) | WO2021232788A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021232788A1 (en) * | 2020-05-21 | 2021-11-25 | 中国科学院深圳先进技术研究院 | Pacemaking switching circuit, pacemaking switching apparatus, and implantable cardiac pacemaker |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201147314Y (en) * | 2007-10-11 | 2008-11-12 | 复旦大学 | Electrocardiogram R wave fast detecting electric appliance for cardiac defibrillator |
| EP2441491B1 (en) * | 2010-10-18 | 2013-01-09 | Sorin CRM SAS | Standalone active medical implant, with a circuit for awakening the input on receiving pulses transmitted via the interstitial tissue of the body |
| CN103027675B (en) * | 2012-12-28 | 2015-05-20 | 上海交通大学 | Novel portable three-lead real-time wireless electrocardiogram monitoring system and analyzing method |
| CN104491986B (en) * | 2014-12-16 | 2016-08-17 | 西安交通大学 | A kind of polarity selecting circuit being applied to cardiac pacemaker |
| CN105342601A (en) * | 2015-12-21 | 2016-02-24 | 重庆大学 | Household electrocardiograph detection instrument |
| CN111628741A (en) * | 2020-05-21 | 2020-09-04 | 中国科学院深圳先进技术研究院 | Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker |
-
2020
- 2020-05-21 CN CN202010435648.7A patent/CN111628741A/en active Pending
- 2020-12-25 WO PCT/CN2020/139581 patent/WO2021232788A1/en active Application Filing
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021232788A1 (en) * | 2020-05-21 | 2021-11-25 | 中国科学院深圳先进技术研究院 | Pacemaking switching circuit, pacemaking switching apparatus, and implantable cardiac pacemaker |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021232788A1 (en) | 2021-11-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105311750B (en) | A kind of sacral nerve stimulation system | |
| DE60104821T2 (en) | IMPLANTABLE MEDICAL DEVICE WITH AUTO-ACTUATED LOGIC | |
| JP2002502641A (en) | Implantable device with digital waveform telemetry | |
| CN204049971U (en) | A kind of intelligent wireless snore stopper | |
| CN108096703B (en) | Multi-channel transcranial electrical stimulation device and method thereof | |
| CN101612451A (en) | Chargeable implant cardiac pacemaker device and charging method thereof | |
| CN108578891B (en) | Hardware circuit of pain electric pulse therapeutic apparatus | |
| CN204091974U (en) | A kind of Wearable ECG detector | |
| CN111628741A (en) | Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker | |
| US20240165414A1 (en) | Methods, systems, and devices for improving communication between external devices and implantable medical devices | |
| CN203458691U (en) | Implantable neural electrical stimulation system | |
| CN212392861U (en) | Pace-making switching circuit, pace-making switching device and implantable cardiac pacemaker | |
| CN108853722A (en) | A kind of control system of transcutaneous electrical stimulation physics headache therapeutic equipment | |
| CN112754503A (en) | Real-time monitoring device and method of implanted low-power-consumption closed-loop self-response system | |
| CN201437021U (en) | Chargeable implanted cardiac pacemaker system | |
| CN205268832U (en) | Implanted sacrum neural stimulator | |
| CN209347931U (en) | A kind of patch type headache is easypro to sleep instrument | |
| CN106725438A (en) | Without conducting wire standard cardioelectric patient monitor | |
| CN200966842Y (en) | Temporary cardiac analyser | |
| CN113134159B (en) | External electrical stimulation treatment system | |
| CN205864080U (en) | A kind of radio energy transmission system for implanted equipment | |
| CN208785590U (en) | A kind of hardware circuit of pain electric pulse therapeutic equipment | |
| CN208017932U (en) | A kind of control system through cranial nerve physical therapy apparatus | |
| CN202909297U (en) | Temporary diaphragm stimulator | |
| CN205268826U (en) | Amazing system of sacral nerve |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |