CN111616678B - Restenosis monitoring device and method based on intelligent coronary stent - Google Patents
Restenosis monitoring device and method based on intelligent coronary stent Download PDFInfo
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- CN111616678B CN111616678B CN202010305502.0A CN202010305502A CN111616678B CN 111616678 B CN111616678 B CN 111616678B CN 202010305502 A CN202010305502 A CN 202010305502A CN 111616678 B CN111616678 B CN 111616678B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6862—Stents
Abstract
The invention provides a restenosis monitoring device and method based on an intelligent coronary stent, which comprises a first blood state detection device, a second blood state detection device, a third blood state detection device and an external data processing device, wherein the first blood state detection device is connected with the second blood state detection device; the blood condition detection device includes: the system comprises a sensor group, an inner processor, an energy supply device and a radio frequency emission module; the external data processing device comprises a radio frequency receiving module, a memory and a data processor; the radio frequency receiving module is used for receiving the electric signal from the radio frequency transmitting module, the memory is used for storing the electric signal, and the data processor periodically calls the electric signal from the memory; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the determination section Δ Sn, the external data processing apparatus simultaneously transmits an alarm notification to the patient and the hospital.
Description
Technical Field
The invention relates to the technical field of medical detection, in particular to a restenosis monitoring device and method based on an intelligent coronary artery stent.
Background
In the current society, the incidence of cardiovascular diseases is higher and higher due to the acceleration of life rhythm and the lack of unscientific dietary habits, self-health care consciousness and other factors, and the number of people who die of the cardiovascular diseases reaches 1500 thousands every year all over the world, and the people live at the head of various causes of death. At present, more than 2.7 hundred million patients with cardiovascular diseases in China die of nearly 300 million people with cardiovascular diseases each year, accounting for 51 percent of the total death causes of China each year, and the cardiovascular disease rate is continuously increasing along with the aging trend of population.
The cardiovascular disease has the characteristics of high morbidity, high mortality, high recurrence rate and many complications, the coronary heart disease is a common cardiovascular disease, and is a heart disease which is characterized in that blood vessels supplying heart nutrients, namely coronary arteries, are subjected to severe atherosclerosis or spasm to cause the coronary arteries to be narrowed or blocked to form thrombus and cause lumen occlusion to cause myocardial ischemia and hypoxia or infarction, is also called ischemic heart disease and is clinically mainly manifested as angina or myocardial infarction. The treatment methods of coronary heart disease are generally divided into three categories, i.e., drug treatment, surgical operation and interventional treatment. Although the medicament has a plurality of advantages, the medicament has long period, slow effect and large side effect, and the conventional medicament is difficult to eliminate a large amount of lipid plaques accumulated on the inner wall of the artery so as to ensure that the blood vessel is unblocked. The heart coronary artery stent is the most important part in the coronary heart disease operation, and after the intervention operation of the heart coronary artery stent is completed, the heart coronary artery stent needs to be periodically reviewed.
In China, with the improvement of living standard, more and more people in remote areas can select hospitals in developed cities far away from living areas, such as the north, the upper reaches and the like, to perform operations when performing the heart coronary artery stent operation; repeated review can add some difficulty to the travel of these patients.
To this end, the present invention provides an intelligent coronary stent based restenosis monitoring device and method to at least partially solve the above problems.
Disclosure of Invention
In this summary, concepts in a simplified form are introduced that are further described in the detailed description section. The summary of the invention is not intended to identify key features or essential features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter.
In order to overcome the problems in the prior art, the invention provides a restenosis monitoring device based on an intelligent coronary stent, which comprises a first blood state detection device, a second blood state detection device, a third blood state detection device and an external data processing device, wherein the first blood state detection device is connected with the second blood state detection device; the first blood state detection device, the second blood state detection device and the third blood state detection device are all arranged in a coronary artery stent; the first blood state detection device and the third blood state detection device are arranged at two ends of the coronary artery stent, and the second blood state detection device is arranged in the middle of the coronary artery stent;
the blood condition detection device includes: the device comprises a sensor group, an inner processor, an energy supply device and a radio frequency emission module; the external data processing device comprises a radio frequency receiving module, a memory and a data processor; the radio frequency receiving module is used for receiving the electric signal from the radio frequency transmitting module, the memory is used for storing the electric signal, and the data processor periodically calls the electric signal from the memory;
the memory comprises an operation formula of an arterial blood real-time state weighing value M and a blood state function G, wherein the operation formula of the blood state function G is as follows:
the memory is stored with preset blood state function weighing values and preset fluctuation values delta K, and the blood state function weighing values comprise a first weighing value K1, a second weighing value K2 and a third weighing value K3; the memory generates a judgment interval delta Sn based on the preset blood state function weighing value and the preset fluctuation value delta K, wherein n is a judgment interval number; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the determination interval Δ Sn, the external data processing device simultaneously transmits an alarm notification to the patient and the hospital.
Further, the judgment section includes: a first determination section (Δ S1 Δ S2), a second determination section (Δ S3 Δ S4), and a third determination section (Δ S5 Δ S6); Δ S1= K1+0.1 Δ K, Δ S2= K1-0.1 Δ K, Δ S3= K2+ Δ K, Δ S4= K2- Δ K, Δ S5= K3+10 Δ K, Δ S6= K3-10 Δ K, where Δ K is a preset fluctuation value, K1 is a first metric value, K2 is a second metric value, and K3 is a third metric value;
when the value of the blood state function G is larger than delta S1 and smaller than delta S4, the coronary artery generates restenosis phenomenon, and the restenosis phenomenon generates in-stent, the external data processing device sends corresponding information to the hospital;
when the value of the blood state function G is larger than delta S3 and smaller than delta S6, the coronary artery generates restenosis phenomenon, and the restenosis phenomenon generates in-stent, the external data processing device sends corresponding information to the hospital;
when the value of the blood status function G is greater than Δ S5 or when the value of the blood status function G is less than Δ S2; the restenosis phenomenon occurs in the coronary artery and extends outside the stent, the external data processing device sending corresponding information to the hospital.
Further, the energy supply device supplies electric energy to the sensor group and the inner processor respectively, the sensor group transmits detected electric signals to the inner processor, the inner processor converts blood flow rate signals and blood pressure signals into digital signals and loads integrated circuit ID and time stamp information, and the inner processor transmits the digital signals to the external processing device through the radio frequency transmission module.
Further, the blood state detection device further comprises a heart coronary artery stent shell, and the sensor group comprises a flow velocity sensor group and a pressure sensor group; the pressure sensor group comprises a first pressure sensor, a second pressure sensor, a third pressure sensor and a fourth pressure sensor, and the flow rate sensor group comprises a first flow rate sensor, a second flow rate sensor, a third flow rate sensor and a fourth flow rate sensor.
Further, the first pressure sensor, the second pressure sensor, the third pressure sensor, and the fourth pressure sensor are disposed on an inner wall of the cardiac coronary stent shell;
the first flow sensor, the second flow sensor, the third flow sensor and the fourth flow sensor are disposed on an inner wall of the cardiac coronary stent housing.
Further, the blood condition detection means includes the first blood condition detection means, the second blood condition detection means, and the third blood condition detection means, and a blood pressure function F is provided in the memory of each of the blood condition detection means n (P) and the blood flow velocity function V n (v)。
Further, the blood pressure function is F n (P1 ', P2', P3', P4'); p1' is the real-time pressure detected by the first pressure sensor; p2' is the real-time pressure detected by the second pressure sensor; p3' is the real-time pressure detected by the third pressure sensor; p4' is the real-time pressure detected by the fourth pressure sensor; function of blood flow velocity of V n (v 1', v2', v3', v4 '), v1' being the real-time flow rate detected by the first flow rate sensor; v2' is the real-time flow rate detected by the second flow sensor; v3' is the real-time flow rate detected by the third flow rate sensor; v4' is the real-time flow rate detected by the fourth flow rate sensor.
Further, the memory stores a blood standard flow velocity V0 and a blood standard pressure P0 of the artery under normal conditions.
Further, the data processor calls a blood standard flow velocity V0 to compare with a real-time flow velocity V1 'detected by the first flow velocity sensor, a real-time flow velocity V2' detected by the second flow velocity sensor, a real-time flow velocity V3 'detected by the third flow velocity sensor, and a real-time flow velocity V4' detected by the fourth flow velocity sensor, respectively, if only one real-time flow velocity value not equal to the blood standard flow velocity V0 exists in all the flow velocity data, V is determined, and V is determined n (v) =1 if there are only two real-time flow rates in the total flow rate dataThe value is not equal to the blood standard flow velocity V0, then V n (v) =2, if there are only three real-time flow rate values in the total flow rate data that are not equal to the blood standard flow rate V0, then V n (v) =3, if there are only four real-time flow rate values in the total flow rate data not equal to the blood standard flow rate V0, then V n (v)＝4。
Further, the data processor calls a blood standard pressure P0 to compare with the real-time pressure P1 'detected by the first pressure sensor, the real-time pressure P2' detected by the second pressure sensor, the real-time pressure P3 'detected by the third pressure sensor and the real-time pressure P4' detected by the fourth pressure sensor, respectively, if only one real-time pressure value less than or equal to the blood standard pressure P0 exists in all the pressure data, F is determined n (P) =1, if there are only two real-time pressure values in the total pressure data that are less than or equal to the blood standard pressure P0, then F n (P) =2, if there are only three real-time pressure values in the total pressure data that are less than or equal to the blood standard pressure P0, then F n (P) =3, if only four real-time pressure values in all pressure data are less than or equal to the blood standard pressure P0, F n (P)＝4。
The invention also provides a restenosis monitoring method based on the intelligent coronary stent, which comprises the following steps:
the pressure sensor groups of the first, second and third blood condition detection devices detect pressure data in the respective devices to form a blood pressure function F n (P1’，P2’，P3’，P4’)；
The flow rate sensor groups of the first, second and third blood condition detection devices detect flow rate data in the respective devices to form a blood flow rate function V n (v1’，v2’，v3’，v4’)；
The data processor compares the blood standard pressure P0 with the real-time pressure, and the data processor is a blood pressure function F according to the comparison result n (P) assigning values;
the data processor converts bloodComparing the standard flow rate V0 with the real-time flow rate, and using the data processor as a blood flow rate function V according to the comparison result n (v) Assigning;
the memory is used for storing a preset blood state function weighing value and a preset fluctuation value delta K, the memory generates a judgment interval delta Sn based on the preset blood state function weighing value and the preset fluctuation value delta K, and n is a judgment interval number; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the judgment interval Delta Sn, the external data processing device simultaneously sends alarm notification to the patient and the hospital.
Compared with the prior art, the invention has the following advantages:
the invention provides a restenosis monitoring device and method based on an intelligent coronary artery stent, wherein the device is different from the prior art in that the device is provided with three blood state detection devices, and each detection device is provided with a sensor group; the pressure sensor groups of the first, second and third blood condition detection devices detect pressure data in the respective devices to form a blood pressure function F n (P1 ', P2', P3', P4'); the flow rate sensor groups of the first, second and third blood condition detection devices detect flow rate data in the respective devices to form a blood flow rate function V n (v 1', v2', v3', v 4'); the data processor compares the blood standard pressure P0 with the real-time pressure, and the data processor is a blood pressure function F according to the comparison result n (P) assigning a value; the data processor compares the blood standard flow velocity V0 with the real-time flow velocity, and the data processor takes the blood flow velocity function V as the comparison result n (v) And (7) assigning values.
The memory comprises an operation formula of an arterial blood real-time state weighing value M and a blood state function G, wherein the operation formula of the blood state function G is as follows:
the memory is stored with preset blood state function weighing values and preset fluctuation values delta K, and the blood state function weighing values comprise a first weighing value K1, a second weighing value K2 and a third weighing value K3; the memory generates a judgment interval delta Sn based on the preset blood state function weighing value and the preset fluctuation value delta K, wherein n is a judgment interval number; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the judgment interval Delta Sn, the external data processing device simultaneously sends alarm notification to the patient and the hospital.
Further, when the value of the blood state function G is larger than Δ S1 and smaller than Δ S4, the coronary artery generates a restenosis phenomenon, and the restenosis phenomenon generates a re-stent, the external data processing device sends corresponding information to the hospital; when the value of the blood state function G is larger than delta S3 and smaller than delta S6, the coronary artery generates restenosis phenomenon, and the restenosis phenomenon generates in-stent, the external data processing device sends corresponding information to the hospital; when the value of the blood status function G is greater than Δ S5 or when the value of the blood status function G is less than Δ S2; the restenosis phenomenon occurs in the coronary artery and extends outside the stent, the external data processing device sending corresponding information to the hospital.
The restenosis monitoring device based on the intelligent coronary artery stent can avoid the trouble of repeated rechecking of a patient; the specific interval judgment method of the invention can judge the specific position of the occurrence of the restenosis state, so that medical personnel can know the physical condition of the patient at the first time, and the diagnosis efficiency is improved.
Drawings
In order that the advantages of the invention will be readily understood, a more particular description of the invention briefly described above will be rendered by reference to specific embodiments that are illustrated in the appended drawings. Understanding that these drawings depict only typical embodiments of the invention and are not therefore to be considered to be limiting of its scope, the invention will be described and explained with additional specificity and detail through the use of the accompanying drawings.
Fig. 1 is a schematic structural diagram of an embodiment of a restenosis monitoring device based on an intelligent coronary stent according to the present invention;
FIG. 2 is a schematic diagram of a sensor arrangement of the restenosis monitoring device based on an intelligent coronary stent according to the present invention;
fig. 3 is a schematic structural diagram of an embodiment of the arterial stent according to the invention.
Description of the reference numerals:
1. a cardiac coronary stent shell; 11. a first blood condition detection device; 12. a second blood condition detection device; 13. a third blood condition detection device; 21. a first pressure sensor; 22. a second pressure sensor; 23. a third pressure sensor; 24. a fourth pressure sensor; 31. a first flow rate sensor; 32. a second flow rate sensor; 33. a third flow rate sensor; 34. a fourth flow rate sensor; 4. a lateral support structure; 5. a plurality of longitudinal support structures.
Detailed Description
In the following description, numerous specific details are set forth in order to provide a more thorough understanding of the present invention. It will be apparent, however, to one skilled in the art, that embodiments of the invention may be practiced without one or more of these specific details. In other instances, well-known features have not been described in detail so as not to obscure the embodiments of the invention.
In the following description, a detailed structure will be presented for a thorough understanding of embodiments of the invention. It is apparent that the implementation of the embodiments of the present invention is not limited to the specific details familiar to those skilled in the art. The following detailed description of preferred embodiments of the invention, however, the invention is capable of other embodiments in addition to those detailed.
In the description of the present invention, the terms "inside", "outside", "longitudinal", "transverse", "upper", "lower", "top", "bottom", and the like indicate orientations or positional relationships based on those shown in the drawings, and are for convenience only to describe the present invention without requiring the present invention to be necessarily constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
Referring to fig. 1, the present invention provides a restenosis monitoring device and method based on an intelligent coronary stent, which includes a first blood state detection device 11, a second blood state detection device 12, a third blood state detection device 13 and an external data processing device. The blood condition detection device includes: the device comprises a sensor group, an inner processor, an energy supply device and a radio frequency emission module; in the invention, the three blood state detection devices comprise a first radio frequency transmission module, a second radio frequency transmission module and a third radio frequency transmission module; the external data processing device comprises a radio frequency receiving module, a memory and a data processor; the radio frequency receiving module is used for receiving electric signals from the first radio frequency transmitting module, the second radio frequency transmitting module and the third radio frequency transmitting module, the memory is used for storing the electric signals, and the data processor periodically calls the electric signals from the memory and carries out blood flow speed state analysis according to the electric signals.
The sensor group comprises a flow velocity sensor group and a pressure sensor group; in the embodiment illustrated in fig. 2, the pressure sensor group comprises a first pressure sensor 21, a second pressure sensor 22, a third pressure sensor 23 and a fourth pressure sensor 24, the first pressure sensor 21, the second pressure sensor 22, the third pressure sensor 23 and the fourth pressure sensor 24 being arranged on the inner wall of the heart coronary stent housing 1; the flow velocity sensor group comprises a first flow velocity sensor 31, a second flow velocity sensor 32, a third flow velocity sensor 33 and a fourth flow velocity sensor 34, and the first flow velocity sensor 31, the second flow velocity sensor 32, the third flow velocity sensor 33 and the fourth flow velocity sensor 34 are arranged on the inner wall of the heart coronary artery stent shell 1.
In some embodiments of the present invention, orthographic projections of the first pressure sensor 21, the second pressure sensor 22, the third pressure sensor 23 and the fourth pressure sensor 24 on a plane perpendicular to the axial direction of the arterial stent shell are uniformly distributed along the inner wall of the arterial stent shell 1 at intervals in the circumferential direction; the orthographic projections of the first flow velocity sensor 31, the second flow velocity sensor 32, the third flow velocity sensor 33 and the fourth flow velocity sensor 34 on a plane vertical to the axial direction of the arterial stent shell are uniformly distributed along the circumferential direction of the inner wall of the arterial stent shell 1 at intervals.
In the blood condition detection device, the energy supply device supplies electric energy to the sensor group and the inner processor respectively, the sensor group transmits detected electric signals to the inner processor, the inner processor converts blood flow rate signals and blood pressure signals into digital signals, loads integrated circuit ID and time stamp information, and transmits the digital signals to the external processing device through the radio frequency transmission module. In some embodiments of the present invention, the energy supply device is a micro battery, and the energy supply device directly supplies electric energy to the sensor group and the inner processor; the energy supply device can also receive electromagnetic waves radiated into the body by an external processing device and supply electric energy for the sensor group and the inner processor by means of wireless radio frequency energy collection.
Referring to fig. 3, in some embodiments of the present invention, the cardiac coronary stent comprises more than two lateral support structures 4 and a plurality of longitudinal support structures 5, each lateral support structure 4 being formed as a loop-shaped stent by bending a wire; two adjacent annular supports are fixedly connected through a plurality of longitudinal supporting structures 5 which are arranged in a staggered mode, so that the supports are unfolded to form a net-shaped structure. The annular support can adopt a sine wave structure or a sawtooth wave structure. Wherein, the other end at every section support is provided with insulating material respectively, fixes the steadiness of this section of support structure through insulating material. The first blood state detection device 11, the second blood state detection device 12 and the third blood state detection device 13 are all arranged in the coronary artery stent; the first blood condition detection means 11 and the third blood condition detection means 13 are arranged at both ends of the coronary stent, and the second blood condition detection means 12 is arranged in the middle of the coronary stent.
The radio frequency receiving device receives the digital signal from the radio frequency transmitting device, and the memory is provided with a blood pressure function F n (P) and blood flow velocity function V n (v)。
In particular, the blood pressure contentNumber F n (P1 ', P2', P3', P4'); p1' is the real-time pressure detected by the first pressure sensor 21; p2' is the real-time pressure detected by the second pressure sensor 22; p3' is the real-time pressure detected by the third pressure sensor 23; p4' is the real-time pressure detected by the fourth pressure sensor 24; function of blood flow velocity of V n (v 1', v2', v3', v4 '), v1' being the real-time flow rate detected by the first flow rate sensor 31; v2' is the real-time flow rate detected by the second flow sensor 32; v3' is the real-time flow rate detected by the third flow rate sensor 33; v4' is the real-time flow rate detected by fourth flow sensor 34. The memory stores a blood state function G { F } n (P)，V n (v) Wherein n is the number, F n (P) is a function of blood pressure, V n (v) As a function of the blood flow rate.
The first blood state detection device, the second blood state detection device and the third blood state detection device are all arranged in the coronary artery of the heart to be monitored; the memory stores the blood standard flow velocity V0 and the blood standard pressure P0 of the artery under normal conditions.
For each blood state detection device, the data processor calls a blood standard flow velocity V0 to compare with a real-time flow velocity V1 'detected by the first flow velocity sensor, a real-time flow velocity V2' detected by the second flow velocity sensor, a real-time flow velocity V3 'detected by the third flow velocity sensor and a real-time flow velocity V4' detected by the fourth flow velocity sensor respectively, if only one real-time flow velocity value in all the flow velocity data is not equal to the blood standard flow velocity V0, the V is equal to the V0 n (v) =1, and so on, if there are only four real-time flow rate values in the total flow rate data that are not equal to the blood standard flow rate V0, then V n (v)＝4。
The data processor calls a blood standard pressure P0 to be respectively compared with a real-time pressure P1 'detected by the first pressure sensor, a real-time pressure P2' detected by the second pressure sensor, a real-time pressure P3 'detected by the third pressure sensor and a real-time pressure P4' detected by the fourth pressure sensor, if only one real-time pressure value in all pressure data is less than or equal to the blood standard pressure P0, F n (P)＝1By analogy, if only four real-time pressure values in all pressure data are less than or equal to the blood standard pressure P0, F n (P)＝4。
The memory also contains an operation formula of a blood state function G, G { F n (P)，V n (v)}＝
In the formula, V 1 (v) As a function of the blood flow rate of the first blood condition sensing device; v 2 (v) As a function of the blood flow rate of the second blood condition detection means; v 3 (v) As a function of the blood flow rate of the third blood condition detection device; f 1 (P) is a function of the blood pressure of the first blood condition detection means; f 2 (P) is a function of the blood pressure of the second blood condition detection means; f 3 (P) is a function of the blood pressure of the third blood condition detection device.
The memory is stored with preset blood state function weighing values and preset fluctuation values delta K, and the blood state function weighing values comprise a first weighing value K1, a second weighing value K2 and a third weighing value K3; the memory generates a judgment interval delta Sn based on the preset blood state function weighing value and the preset fluctuation value delta K, wherein n is a judgment interval number; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the judgment section Δ Sn, the external data processing device simultaneously transmits an alarm notification to the patient and the hospital.
The judgment section includes: a first determination section (Δ S1 Δ S2), a second determination section (Δ S3 Δ S4), and a third determination section (Δ S5 Δ S6); Δ S1= K1+0.1 Δ K, Δ S2= K1-0.1 Δ K, Δ S3= K2+ Δ K, Δ S4= K2- Δ K, Δ S5= K3+10 Δ K, Δ S6= K3-10 Δ K, where Δ K is a preset fluctuation value, K1 is a first metric value, K2 is a second metric value, and K3 is a third metric value;
when the value of the blood state function G is larger than delta S1 and smaller than delta S4, the coronary artery generates restenosis, and the restenosis generates in a stent, the external data processing device sends corresponding information to the hospital;
when the value of the blood state function G is larger than delta S3 and smaller than delta S6, the coronary artery generates restenosis phenomenon, and the restenosis phenomenon generates in the stent, the external data processing device sends corresponding information to the hospital;
when the value of the blood status function G is greater than Δ S5 or when the value of the blood status function G is less than Δ S2; the restenosis phenomenon occurs in the coronary artery, and the restenosis phenomenon extends to the outside of the stent, and the external data processing device transmits corresponding information to the hospital.
In some embodiments of the present invention, the external data processing device may be disposed on a mobile device such as a watch or a bracelet worn by the patient, and the external data processing device may send the detection result to the patient in real time; the external data processing device may also have a remote communication function, and the external data processing device may transmit the detected condition to the hospital.
Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. Terms such as "component" and the like, when used herein, can refer to either a single part or a combination of parts. Terms such as "mounted," "disposed," and the like, as used herein, may refer to one component as being directly attached to another component or one component as being attached to another component through intervening components. Features described herein in one embodiment may be applied to another embodiment, either alone or in combination with other features, unless the feature is not applicable or otherwise stated in the other embodiment.
The present invention has been described in terms of the above embodiments, but it should be understood that the above embodiments are for purposes of illustration and description only and are not intended to limit the invention to the described embodiments. It will be appreciated by those skilled in the art that many variations and modifications are possible in light of the above teaching and are within the scope of the invention as claimed.
Claims (10)
1. A restenosis monitoring device based on an intelligent coronary stent is characterized by comprising a first blood state detection device, a second blood state detection device, a third blood state detection device and an external data processing device; the first blood state detection device, the second blood state detection device and the third blood state detection device are all arranged in a coronary artery stent; the first blood state detection device and the third blood state detection device are arranged at two ends of the coronary artery stent, and the second blood state detection device is arranged in the middle of the coronary artery stent;
the blood condition detection device includes: the device comprises a sensor group, an inner processor, an energy supply device and a radio frequency emission module; the external data processing device comprises a radio frequency receiving module, a memory and a data processor; the radio frequency receiving module is used for receiving the electric signal from the radio frequency transmitting module, the memory is used for storing the electric signal, and the data processor periodically calls the electric signal from the memory;
the memory comprises an operation formula of an arterial blood real-time state weighing value M and a blood state function G, wherein the operation formula of the blood state function G is as follows:
the memory is stored with preset blood state function weighing values and preset fluctuation values delta K, and the blood state function weighing values comprise a first weighing value K1, a second weighing value K2 and a third weighing value K3; the memory generates a judgment interval delta Sn based on the preset blood state function weighing value and the preset fluctuation value delta K, wherein n is a judgment interval number; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the determination interval Δ Sn, the external data processing device simultaneously transmits an alarm notification to the patient and the hospital.
2. The smart coronary stent based restenosis monitoring device of claim 1, wherein determining an interval comprises: a first determination section (Δ S1 Δ S2), a second determination section (Δ S3 Δ S4), and a third determination section (Δ S5 Δ S6); Δ S1= K1+0.1 Δ K, Δ S2= K1-0.1 Δ K, Δ S3= K2+ Δ K, Δ S4= K2- Δ K, Δ S5= K3+10 Δ K, Δ S6= K3-10 Δ K, where Δ K is a preset fluctuation value, K1 is a first metric value, K2 is a second metric value, and K3 is a third metric value;
when the value of the blood state function G is larger than delta S1 and smaller than delta S4, the coronary artery generates restenosis phenomenon, and the restenosis phenomenon generates in-stent, the external data processing device sends corresponding information to the hospital;
when the value of the blood state function G is larger than delta S3 and smaller than delta S6, the coronary artery generates restenosis phenomenon, and the restenosis phenomenon generates in-stent, the external data processing device sends corresponding information to the hospital;
when the value of the blood status function G is greater than Δ S5 or when the value of the blood status function G is less than Δ S2; the restenosis phenomenon occurs in the coronary artery and extends outside the stent, the external data processing device sending corresponding information to the hospital.
3. The smart coronary stent-based restenosis monitoring device of claim 2, wherein the energy supply device supplies electrical energy to the sensor group and the inner processor, respectively, the sensor group transmits the detected electrical signals to the inner processor, the inner processor converts the blood flow rate signal and the blood pressure signal into digital signals and loads the integrated circuit ID, time stamp information, and the inner processor transmits the digital signals to the external processing device through the rf transmission module.
4. The smart coronary stent-based restenosis monitoring device of claim 2, wherein the blood status detection device further comprises a cardiac coronary stent housing, the sensor set comprising a flow sensor set and a pressure sensor set; the pressure sensor group comprises a first pressure sensor, a second pressure sensor, a third pressure sensor and a fourth pressure sensor, and the flow rate sensor group comprises a first flow rate sensor, a second flow rate sensor, a third flow rate sensor and a fourth flow rate sensor.
5. The smart coronary stent-based restenosis monitoring device of claim 4,
the first pressure sensor, the second pressure sensor, the third pressure sensor and the fourth pressure sensor are disposed on an inner wall of the cardiac coronary stent housing;
the first flow sensor, the second flow sensor, the third flow sensor and the fourth flow sensor are disposed on an inner wall of the cardiac coronary stent housing.
6. The smart coronary stent-based restenosis monitoring device of claim 4, wherein the blood condition detection device includes the first, second, and third blood condition detection devices, a blood pressure function F being provided in the memory of each blood condition detection device n (P) and blood flow velocity function V n (v)。
7. The smart coronary stent-based restenosis monitoring device of claim 6, wherein the blood pressure function is F n (P1’，P2’，P3’，P4’)(ii) a P1' is the real-time pressure detected by the first pressure sensor; p2' is the real-time pressure detected by the second pressure sensor; p3' is the real-time pressure detected by the third pressure sensor; p4' is the real-time pressure detected by the fourth pressure sensor; function of blood flow velocity of V n (v 1', v2', v3', v4 '), v1' being the real-time flow rate detected by the first flow rate sensor; v2' is the real-time flow rate detected by the second flow sensor; v3' is the real-time flow rate detected by the third flow rate sensor; v4' is the real-time flow rate detected by the fourth flow rate sensor.
8. The smart coronary stent-based restenosis monitoring device according to claim 7, wherein the memory stores a normal arterial blood standard flow rate V0 and a normal arterial blood standard pressure P0; the data processor calls a blood standard flow velocity V0 to be respectively compared with a real-time flow velocity V1 'detected by the first flow velocity sensor, a real-time flow velocity V2' detected by the second flow velocity sensor, a real-time flow velocity V3 'detected by the third flow velocity sensor and a real-time flow velocity V4' detected by the fourth flow velocity sensor, if only one real-time flow velocity value is not equal to the blood standard flow velocity V0 in all the flow velocity data, the V is equal to the V0 n (v) =1, if there are only two real-time flow values in the total flow data that are not equal to the blood standard flow V0, then V n (v) =2, if there are only three real-time flow values in the total flow data that are not equal to the blood standard flow rate V0, then V n (v) =3, if there are only four real-time flow rate values in the total flow rate data not equal to the blood standard flow rate V0, then V n (v)＝4。
9. The smart coronary stent-based restenosis monitoring device of claim 8, wherein the data processor retrieves a blood reference pressure P0, which is respectively compared to the real-time pressure P1' detected by the first pressure sensor, the real-time pressure P2' detected by the second pressure sensor, the real-time pressure P3' detected by the third pressure sensor, and the third pressure sensorComparing real-time pressure P4' detected by the four pressure sensors, and if only one real-time pressure value less than or equal to the blood standard pressure P0 exists in all pressure data, F n (P) =1, if only two real-time pressure values are less than or equal to the blood standard pressure P0 in all pressure data, F n (P) =2, if there are only three real-time pressure values in the total pressure data that are less than or equal to the blood standard pressure P0, then F n (P) =3, if only four real-time pressure values in all pressure data are less than or equal to the blood standard pressure P0, F n (P)＝4。
10. A restenosis monitoring method based on an intelligent coronary stent is characterized by comprising the following steps:
the pressure sensor groups of the first, second and third blood condition detection devices detect pressure data in the respective devices to form a blood pressure function F n (P1’，P2’，P3’，P4’)；
The flow rate sensor groups of the first, second and third blood condition detection devices detect flow rate data in the respective devices to form a blood flow rate function V n (v1’，v2’，v3’，v4’)；
The data processor compares the blood standard pressure P0 with the real-time pressure, and the data processor is a blood pressure function F according to the comparison result n (P) assigning values;
the data processor compares the blood standard flow velocity V0 with the real-time flow velocity, and the data processor is a blood flow velocity function V according to the comparison result n (v) Assigning;
the memory is used for storing a preset blood state function weighing value and a preset fluctuation value delta K, the memory generates a judgment interval delta Sn based on the preset blood state function weighing value and the preset fluctuation value delta K, and n is a judgment interval number; when the value of the blood state function G is within the judgment interval delta Sn, the external data processing device does not work; when the value of the blood state function G is outside the determination interval Δ Sn, the external data processing device simultaneously transmits an alarm notification to the patient and the hospital.
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