CN111596019A - Anti-infective drug toxicity automatic detection equipment - Google Patents
Anti-infective drug toxicity automatic detection equipment Download PDFInfo
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- CN111596019A CN111596019A CN202010488201.6A CN202010488201A CN111596019A CN 111596019 A CN111596019 A CN 111596019A CN 202010488201 A CN202010488201 A CN 202010488201A CN 111596019 A CN111596019 A CN 111596019A
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- 238000001514 detection method Methods 0.000 title claims abstract description 21
- 230000002924 anti-infective effect Effects 0.000 title claims abstract description 18
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 title claims abstract description 15
- 206010070863 Toxicity to various agents Diseases 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 30
- 229940079593 drug Drugs 0.000 claims abstract description 15
- 230000007306 turnover Effects 0.000 claims description 19
- 238000003756 stirring Methods 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000004090 dissolution Methods 0.000 claims description 9
- 239000002351 wastewater Substances 0.000 claims description 9
- 231100000041 toxicology testing Toxicity 0.000 claims description 7
- 238000013461 design Methods 0.000 claims description 4
- 230000002441 reversible effect Effects 0.000 claims description 4
- 239000010865 sewage Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 231100000820 toxicity test Toxicity 0.000 claims description 3
- 238000004140 cleaning Methods 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 230000002146 bilateral effect Effects 0.000 claims 1
- 238000000151 deposition Methods 0.000 claims 1
- 239000000843 powder Substances 0.000 description 19
- 238000007514 turning Methods 0.000 description 7
- 230000005540 biological transmission Effects 0.000 description 6
- 230000001988 toxicity Effects 0.000 description 5
- 231100000419 toxicity Toxicity 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000005507 spraying Methods 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 238000013459 approach Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B1/00—Cleaning by methods involving the use of tools
- B08B1/10—Cleaning by methods involving the use of tools characterised by the type of cleaning tool
- B08B1/12—Brushes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B1/00—Cleaning by methods involving the use of tools
- B08B1/30—Cleaning by methods involving the use of tools by movement of cleaning members over a surface
- B08B1/32—Cleaning by methods involving the use of tools by movement of cleaning members over a surface using rotary cleaning members
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/02—Cleaning by the force of jets or sprays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2866—Grinding or homogeneising
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
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- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
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Abstract
The invention discloses automatic anti-infective drug toxicity detection equipment, which comprises a main machine body, wherein a grinding cavity with an upward opening is formed in the main machine body, a grinding disc capable of being turned is arranged in the grinding cavity, the grinding disc is used for grinding drugs when the opening of the grinding disc is upward, a first upright post and a second upright post are fixedly arranged on the top surface of the main machine body, the first upright post is positioned on the left side, and the second upright post is positioned on the right side. The brush ball can automatically clean the grinding disc, and manpower is saved.
Description
Technical Field
The invention relates to the technical field of drug detection, in particular to automatic anti-infective drug toxicity detection equipment.
Background
With the continuous development of science and technology, people also make rapid progress in the medical field, people develop new medicines more and more rapidly, the medicines generally need to be detected when being developed, certain anti-infective medicines also need to be subjected to toxicity detection, traditional medicines are generally in a tablet shape, the medicines generally need to be manually ground into powder when being detected, then the powder is prepared into solution, the solution is detected or tested, the traditional grinding method is manual grinding, the powder is manually transferred into a beaker after being ground, the solution is prepared, and a medicine guiding pestle or a grinding disc needs to be manually cleaned, so that the traditional grinding method is troublesome and wastes manpower.
Disclosure of Invention
The invention aims to provide automatic anti-infective toxicity detection equipment, which is used for overcoming the defects in the prior art.
The automatic anti-infective drug toxicity detection equipment comprises a main machine body, wherein a grinding cavity with an upward opening is formed in the main machine body, a grinding disc capable of being turned over is arranged in the grinding cavity, the grinding disc is used for grinding drugs when the opening is upward, a first upright post and a second support post are fixedly arranged on the top surface of the main machine body, the first upright post is positioned on the left side, the second support post is positioned on the right side, a first cross beam is fixedly arranged between the first upright post and the second support post, a circular table is rotatably arranged at the bottom of the first cross beam, a hemispherical block is detachably arranged on the bottom surface of the circular table, the hemispherical block is positioned right above the grinding disc and used for crushing the drugs in cooperation with the grinding disc, a dissolution cavity is formed in the right side of the grinding cavity and used for dissolving the drugs, and a detection mechanism capable of moving up and down is arranged on the upper side of the dissolution cavity, the detection mechanism is used for detecting the toxicity of a medicine solution, a drainage cavity is formed in the lower wall of the grinding cavity, a lifting plate is arranged in the drainage cavity in a sliding mode, a driven spline sleeve extending up and down is arranged in the lifting plate in a rotating mode, a brush ball is fixedly arranged at the top end of the driven spline sleeve, and the brush ball is used for cleaning the inner wall of the grinding disc to prevent the two medicines from being mixed to influence an experiment result when the grinding disc is used next time.
According to the technical scheme, a second cross beam is fixedly arranged between the first stand column and the second support column, a power motor is fixedly arranged on the top surface of the second cross beam, the bottom end of the power motor is in power connection with a power shaft extending downwards, the power shaft penetrates through the first cross beam and is in running fit with the first cross beam, a lifting block is arranged on the lower side of the first cross beam in a vertical sliding mode, a spline sleeve is arranged in the lifting block in a rotating mode, the power shaft is in spline fit connection with the spline sleeve, the bottom end of the spline sleeve is in fixed fit connection with the top surface of the circular table, an extending portion of the bottom of the power shaft is in spline fit connection with the circular table, and the power shaft drives the hemispherical block to rotate through the work of the power motor, so that medicines are crushed.
According to the technical scheme, the bottom surface of the first cross beam is provided with two bilaterally symmetrical thread blocks in a sliding mode, each thread block is hinged to the lifting block through a connecting rod, a lifting motor is embedded in the first cross beam, the left end of the lifting motor is connected with a transverse screw rod in a power connection mode, the transverse screw rod is located on the rear side of the power shaft, the left part and the right part of the transverse screw rod are designed in an opposite threaded mode, the transverse screw rod is connected with the two thread blocks in a thread fit mode, and the transverse screw rod rotates through the work of the lifting motor and further enables the hemispherical blocks to ascend or descend.
According to the technical scheme, a hydraulic mechanism is fixedly embedded in the first cross beam, the bottom end of the hydraulic mechanism is in power connection with the detection mechanism, the hydraulic mechanism is used for controlling the detection mechanism to ascend or descend, a curved plate is fixedly arranged on the top surface of the main machine body and used for preventing medicine from splashing to the right side, a funnel is fixedly arranged on the second support, a water inlet pipe is communicated with the left side of the funnel, and the bottom opening of the water inlet pipe is aligned to the dissolution cavity so that solution in the funnel can enter the dissolution cavity.
According to the further technical scheme, a transmission shaft extending up and down is arranged in the first stand column in a rotating mode, the top end of the transmission shaft is in power connection with the power shaft through a first belt, a first bevel gear is fixedly arranged at the bottom end of the transmission shaft, a bottom shaft extending left and right is arranged in the main machine body in a rotating mode, a second bevel gear meshed with the first bevel gear is fixedly arranged at the left end of the bottom shaft, a third bevel gear is fixedly arranged at the right end of the bottom shaft, a stirring rotating shaft extending up and down is rotatably arranged on the lower side of the dissolving cavity, a stirring disc is rotatably arranged on the bottom wall of the dissolving cavity, the bottom surface of the stirring disc is fixedly connected with the top end of the stirring rotating shaft, a fourth bevel gear is fixedly arranged at the bottom end of the stirring rotating shaft, and the fourth bevel gear.
According to the further technical scheme, a fifth bevel gear is fixedly arranged on the periphery of the middle part of the bottom shaft, a driven spline shaft extending up and down is rotatably arranged on the bottom wall of the drainage cavity, a sixth bevel gear is fixedly arranged at the bottom end of the driven spline shaft and meshed with the fifth bevel gear, the driven spline shaft is in spline fit connection with the driven spline housing, a vertical screw rod extending up and down is rotatably arranged at the part, close to the left side, of the drainage cavity, the vertical screw rod is in thread fit connection with the lifting plate, a turnover motor is fixedly embedded at the left side of the grinding cavity, the right end of the turnover motor is in power connection with a turnover shaft, a turnover gear is fixedly arranged at the right end of the turnover shaft, a short shaft is rotatably arranged at the lower side of the turnover shaft, the short shaft is in power connection with the turnover shaft through a second belt, and a power bevel gear, and a driven bevel gear is fixedly arranged at the top end of the vertical screw rod and is meshed with the power bevel gear.
Further technical scheme, grind the chamber with it is equipped with swing gear to rotate between the dissolution chamber, the swing gear downside the swing motor has been inlayed to the main part internal solid, swing motor's top power is connected with power gear, power gear with swing gear meshing design, swing motor can just reverse rotation, both ends all have set firmly the back shaft about the abrasive disc, the right side the back shaft with swing gear normal running fit, it is left the driven gear has set firmly on the periphery of back shaft, driven gear can with upset gear engagement.
According to the technical scheme, a waste water cavity is communicated with the lower side of the dissolving cavity and used for storing sewage, a baffle plate capable of closing the bottom of the dissolving cavity is arranged between the waste water cavity and the dissolving cavity, and a water spraying opening capable of spraying water is fixedly arranged on the bottom wall of the grinding cavity.
The invention has the beneficial effects that: the tablet grinding machine can automatically manufacture tablets into medicinal powder by the mutual cooperation of the downward movement and rotation of the hemispherical block and the grinding disc, so that the trouble of manually manufacturing the medicinal powder is saved, the labor is saved, meanwhile, after the medicinal powder is ground, the grinding disc can automatically swing around the swing gear as a circle center, the medicinal powder in the grinding disc enters the dissolving cavity, the trouble of manually transferring the medicinal powder is saved, meanwhile, after the medicinal powder is ground, the grinding disc can automatically turn over, so that the brush ball can automatically clean the grinding disc, the convenience is greatly improved, the labor is saved, and meanwhile, the tablet grinding machine is simple in structure, convenient to operate and convenient to use.
Drawings
FIG. 1 is a schematic view of the internal structure of an automatic anti-infective drug toxicity test device of the present invention;
FIG. 2 is a schematic view of the present invention with the abrasive disk facing down;
FIG. 3 is a top view of the curved plate of the present invention;
fig. 4 is a partially enlarged view of a in fig. 1 according to the present invention.
Detailed Description
For purposes of making the objects and advantages of the present invention more apparent, the following detailed description of the invention, taken in conjunction with the examples, is to be understood that the following text is only intended to describe one or more specific embodiments of the invention, and is not intended to strictly limit the scope of the invention as specifically claimed, and as used herein, the terms top, bottom, left and right are not limited to strict geometric definitions, but rather include tolerances for reasonable and inconsistent machining or human error, the specific features of an automated anti-infective toxicity test apparatus being described in detail below:
referring to fig. 1 to 4, an automatic anti-infective drug toxicity testing apparatus according to an embodiment of the present invention includes a main body 10, a grinding cavity 49 with an upward opening is formed in the main body 10, a reversible grinding disc 71 is disposed in the grinding cavity 49, the grinding disc 71 is used for grinding drugs when the opening is upward, a first upright post 11 and a second upright post 29 are fixedly disposed on a top surface of the main body 10, the first upright post 11 is located on a left side, the second upright post 29 is located on a right side, a first cross beam 93 is fixedly disposed between the first upright post 11 and the second upright post 29, a circular truncated cone 22 is rotatably disposed at a bottom of the first cross beam 93, a hemispherical block 23 is detachably mounted on a bottom surface of the circular truncated cone 22, the hemispherical block 23 is located directly above the grinding disc 71, and the hemispherical block 23 is used for grinding drugs in cooperation with the grinding disc 71, dissolve chamber 56 has been seted up on grinding chamber 49's right side, dissolve chamber 56 is used for dissolving the medicine, the upside that dissolves chamber 56 is equipped with detection mechanism 26 that can reciprocate, detection mechanism 26 is used for detecting the toxicity of medicine solution, water drainage chamber 70 has been seted up on grinding chamber 49's the lower wall, it is equipped with lifter plate 55 to slide from top to bottom in the water drainage chamber 70, the driven spline housing 52 that extends from top to bottom is equipped with in the lifter plate 55 internal rotation, driven spline housing 52's top has set firmly brush ball 51, brush ball 51 is used for wasing grinding disk 71 inner wall prevents when using next time, and two kinds of medicines mix and influence the experimental result.
Advantageously or exemplarily, a second cross-member 12 is fixedly arranged between said first upright 11 and said second upright 29, a power motor 14 is fixedly arranged on the top surface of the second beam 12, a power shaft 20 extending downwards is dynamically connected to the bottom end of the power motor 14, the power shaft 20 penetrates through the first cross beam 93 and is in running fit with the first cross beam 93, the lower side of the first beam 93 is provided with a lifting block 24 in a vertical sliding manner, the lifting block 24 is internally and rotatably provided with a spline housing 25, the power shaft 20 is in spline fit connection with the spline housing 25, the bottom end of the spline housing 25 is fixedly in spline fit connection with the top surface of the circular truncated cone 22, the extending part of the bottom of the power shaft 20 is in spline fit connection with the circular truncated cone 22, the power shaft 20 drives the hemispherical block 23 to rotate through the operation of the power motor 14, so that the medicine is crushed.
Beneficially or exemplarily, two bilaterally symmetrical thread blocks 17 are slidably disposed on the bottom surface of the first cross beam 93, each thread block 17 is hinged to the lifting block 24 through a connecting rod 18, a lifting motor 16 is fixedly embedded in the first cross beam 93, a transverse screw 19 is dynamically connected to the left end of the lifting motor 16, the transverse screw 19 is located at the rear side of the power shaft 20, the left and right threads of the transverse screw 19 are designed in an opposite manner, the transverse screw 19 is in thread fit connection with the two thread blocks 17, and the transverse screw 19 is rotated by the operation of the lifting motor 16, so that the hemispherical block 23 is lifted or lowered.
Beneficially or exemplarily, a hydraulic mechanism 15 is embedded in the first cross beam 93, a bottom end of the hydraulic mechanism 15 is in power connection with the detection mechanism 26, the hydraulic mechanism 15 is used for controlling the detection mechanism 26 to ascend or descend, a curved plate 57 is fixedly arranged on the top surface of the main body 10, the curved plate 57 is used for preventing the medicine from spilling to the right side, a funnel 27 is fixedly arranged on the second support 29, a water inlet pipe 28 is communicatively arranged on the left side of the funnel 27, and a bottom opening of the water inlet pipe 28 is aligned with the dissolution cavity 56, so that the solution in the funnel 27 can enter the dissolution cavity 56.
Advantageously or exemplarily, a drive shaft 47 extending up and down is rotatably provided in the first upright 11, the top end of the transmission shaft 47 is in power connection with the power shaft 20 through a first belt 13, a first bevel gear 46 is fixedly arranged at the bottom end of the transmission shaft 47, a bottom shaft 42 extending left and right is rotatably arranged in the main body 10, a second bevel gear 45 meshed with the first bevel gear 46 is fixedly arranged at the left end of the bottom shaft 42, the right end of the bottom shaft 42 is fixedly provided with a third bevel gear 40, the lower side of the dissolving cavity 56 is rotatably provided with a stirring rotating shaft 74 extending up and down, the bottom wall of the dissolving cavity 56 is rotatably provided with a stirring disc 34, the bottom surface of the stirring disc 34 is fixedly connected with the top end of the stirring rotating shaft 74, a fourth bevel gear 41 is fixedly arranged at the bottom end of the stirring rotating shaft 74, the fourth bevel gear 41 is meshed with the third bevel gear 40,
beneficially or exemplarily, a fifth bevel gear 43 is fixedly arranged on the outer periphery of the middle part of the bottom shaft 42, a driven spline shaft 53 extending up and down is rotatably arranged on the bottom wall of the drainage cavity 70, a sixth bevel gear 44 is fixedly arranged at the bottom end of the driven spline shaft 53, the sixth bevel gear 44 is engaged with the fifth bevel gear 43, the driven spline shaft 53 is in spline fit connection with the driven spline housing 52, a vertical screw 48 extending up and down is rotatably arranged in the drainage cavity 70 near the left side, the vertical screw 48 is in thread fit connection with the lifting plate 55, a turning motor 58 is fixedly embedded at the left side of the grinding cavity 49, a turning shaft 59 is in power connection with the right end of the turning motor 58, a turning gear 60 is fixedly arranged at the right end of the turning shaft 59, a short shaft 63 is rotatably arranged at the lower side of the turning shaft 59, and the short shaft 63 is in power connection with the turning shaft 59 through a second belt 54, the right end of the short shaft 63 is fixedly provided with a power bevel gear 65, the top end of the vertical screw rod 48 is fixedly provided with a driven bevel gear 66, the driven bevel gear 66 and the power bevel gear 65 are designed in a meshed mode, the overturning shaft 59 drives the short shaft 63 to rotate through the operation of the overturning motor 58, and then the vertical screw rod 48 rotates, so that the lifting plate 55 ascends or descends.
Beneficially or exemplarily, a swing gear 30 is rotatably disposed between the grinding chamber 49 and the dissolving chamber 56, a swing motor 33 is fixedly embedded in the main body 10 below the swing gear 30, a power gear 31 is dynamically connected to a top end of the swing motor 33, the power gear 31 is in meshing design with the swing gear 30, the swing motor 33 can rotate in forward and reverse directions, support shafts 32 are fixedly disposed at both left and right ends of the grinding disc 71, the support shaft 32 at the right side is in rotating fit with the swing gear 30, a driven gear 61 is fixedly disposed on an outer periphery of the support shaft 32 at the left side, and the driven gear 61 can be meshed with the turnover gear 60.
Advantageously or exemplarily, a waste water cavity 38 is communicated with the lower side of the dissolving cavity 56, the waste water cavity 38 is used for storing sewage, a baffle 35 capable of closing the bottom of the dissolving cavity 56 is arranged between the waste water cavity 38 and the dissolving cavity 56, and a water jet 50 capable of spraying water is fixedly arranged on the bottom wall of the grinding cavity 49.
When in use, firstly, the medicine is put into the grinding disc 71, then the lifting motor 16 is controlled to work, the transverse screw rod 19 is made to rotate, and then the two thread blocks 17 are made to approach each other, so that the lifting block 24 moves downwards, and further the circular table 22 drives the hemispherical block 23 to move downwards, and simultaneously the power motor 14 works, so that the power shaft 20 rotates, and further the spline sleeve 25 drives the circular table 22 to rotate, and further the hemispherical block 23 rotates, so that the hemispherical block 23 pulverizes and grinds the medicine into powder, then the lifting motor 16 is controlled to work reversely, so that the transverse screw rod 19 rotates, and further the circular table 22 drives the hemispherical block 23 to move upwards, then the swing motor 33 is controlled to work, so that the power gear 31 drives the swing gear 30 to rotate, so that the medicine powder in the grinding disc 71 enters the dissolving cavity 56, and then the solution is added into the funnel 27 to dissolve the medicine powder, and then the grinding disc 71 is controlled to return, simultaneously, the operation of the turnover motor 58 is controlled, the turnover gear 60 drives the driven gear 61 to rotate, the grinding disc 71 is turned over, the short shaft 63 drives the power bevel gear 65 to rotate, the driven bevel gear 66 drives the vertical screw rod 48 to rotate, the lifting plate 55 moves upwards, the brush balls 51 move upwards to contact with the inner wall of the grinding disc 71, the stirring rotating shaft 74 is controlled to operate again, the transmission shaft 47 rotates, the first bevel gear 46 drives the second bevel gear 45 to rotate, the bottom shaft 42 rotates, the fifth bevel gear 43 drives the sixth bevel gear 44 to rotate, the driven spline shaft 53 drives the driven spline housing 52 to rotate, the brush balls 51 rotate, the water spraying opening 50 is controlled to spray water, the brush balls 51 brush the inner wall of the grinding disc 71, the lower half ball block 23 is manually disassembled to clean, the third bevel gear 40 drives the fourth bevel gear 41 to rotate, and then make agitator disk 34 rotate to make the powder in dissolving the chamber 56 accelerate to dissolve, after dissolving, control hydraulic pressure mechanism 15 moves down, and then make detection mechanism 26 get into dissolving the chamber 56 and detect toxicity, control baffle 35 opens after detecting, make the waste sample in dissolving the chamber 56 get into waste water chamber 38, and add the washing liquid to dissolving the chamber 56 and wash.
The invention has the beneficial effects that: the tablet grinding machine can automatically manufacture tablets into medicinal powder by the mutual cooperation of the downward movement and rotation of the hemispherical block and the grinding disc, so that the trouble of manually manufacturing the medicinal powder is saved, the labor is saved, meanwhile, after the medicinal powder is ground, the grinding disc can automatically swing around the swing gear as a circle center, the medicinal powder in the grinding disc enters the dissolving cavity, the trouble of manually transferring the medicinal powder is saved, meanwhile, after the medicinal powder is ground, the grinding disc can automatically turn over, so that the brush ball can automatically clean the grinding disc, the convenience is greatly improved, the labor is saved, and meanwhile, the tablet grinding machine is simple in structure, convenient to operate and convenient to use.
It will be apparent to those skilled in the art that various modifications may be made to the above embodiments without departing from the general spirit and concept of the invention. All falling within the scope of protection of the present invention. The protection scheme of the invention is subject to the appended claims.
Claims (8)
1. An anti-infective drug toxicity automatic detection equipment, includes the host computer body, its characterized in that: the grinding machine is characterized in that a grinding cavity with an upward opening is formed in the main machine body, a grinding disc capable of being turned is arranged in the grinding cavity, the grinding disc is used for grinding a medicine when the opening of the grinding disc is upward, a first upright post and a second upright post are fixedly arranged on the top surface of the main machine body, the first upright post is positioned on the left side, the second upright post is positioned on the right side, a first cross beam is fixedly arranged between the first upright post and the second upright post, a round table is rotatably arranged at the bottom of the first cross beam, a hemispherical block is detachably arranged on the bottom surface of the round table and is positioned right above the grinding disc, the hemispherical block is used for grinding the medicine in cooperation with the grinding disc, a dissolving cavity is formed in the right side of the grinding cavity and is used for dissolving the medicine, a detection mechanism capable of moving up and down is arranged on the upper side of the dissolving cavity and is used for detecting the, the grinding disc is characterized in that a drainage cavity is formed in the lower wall of the grinding cavity, a lifting plate is arranged in the drainage cavity in a sliding mode, a driven spline sleeve extending up and down is arranged in the lifting plate in a rotating mode, a brush ball is fixedly arranged at the top end of the driven spline sleeve, and the brush ball is used for cleaning the inner wall of the grinding disc to prevent the situation that the experimental result is influenced by mixing of two medicines when the grinding disc is used next time.
2. The automatic anti-infective drug toxicity testing apparatus of claim 1, wherein: first stand with the second crossbeam has set firmly between the second pillar, the power motor has set firmly on the top surface of second crossbeam, power motor's bottom power connection has downwardly extending's power shaft, the power shaft run through first crossbeam and with first crossbeam normal running fit, the downside of first crossbeam slides from top to bottom and is equipped with the elevator, rotate in the elevator and be equipped with the spline housing, the power shaft with spline housing spline fit connects, the bottom of spline housing with the top surface fixed fit of round platform is connected, the bottom extension of power shaft with round platform spline fit connects.
3. The automatic anti-infective drug toxicity testing apparatus of claim 2, wherein: the bottom surface of first crossbeam is gone up to slide and is equipped with two bilateral symmetry's screw thread piece, every the screw thread piece with it is articulated through the connecting rod between the elevator, the embedded elevator motor that has of first crossbeam, elevator motor's left end power is connected with horizontal screw rod, horizontal screw rod is located the rear side of power shaft, two opposite designs of part screw thread about horizontal screw rod, horizontal screw rod and two screw thread piece screw-thread fit connection.
4. An automatic anti-infective drug toxicity test apparatus as claimed in claim 3, wherein: the solid hydraulic pressure mechanism that has inlayed in the first crossbeam, hydraulic pressure mechanism's bottom with detection mechanism power is connected, hydraulic pressure mechanism is used for control detection mechanism rises or descends, the bent plate has set firmly on the top surface of the host computer body, the bent plate is used for preventing the medicine to the right side spill, the funnel has set firmly on the second pillar, the left side intercommunication of funnel is equipped with the inlet tube, the bottom opening of inlet tube is aimed at dissolve the chamber, makes solution in the funnel can get into dissolve the intracavity.
5. The automatic anti-infective drug toxicity testing apparatus of claim 4, wherein: the bottom of the dissolution cavity is rotatably provided with a stirring disc, the bottom surface of the stirring disc is fixedly connected with the top end of the stirring rotating shaft, the bottom end of the stirring rotating shaft is fixedly provided with a fourth bevel gear, and the fourth bevel gear is meshed with the third bevel gear.
6. The automatic anti-infective drug toxicity testing apparatus of claim 5, wherein: a fifth bevel gear is fixedly arranged on the periphery of the middle part of the bottom shaft, a driven spline shaft extending up and down is rotatably arranged on the bottom wall of the drainage cavity, a sixth bevel gear is fixedly arranged at the bottom end of the driven spline shaft and meshed with the fifth bevel gear, the driven spline shaft is in spline fit connection with the driven spline housing, a vertical screw rod extending up and down is rotatably arranged at the part close to the left side in the drainage cavity, the vertical screw rod is in thread fit connection with the lifting plate, a turnover motor is fixedly embedded at the left side of the grinding cavity, the right end of the turnover motor is in power connection with a turnover shaft, a turnover gear is fixedly arranged at the right end of the turnover shaft, a short shaft is rotatably arranged at the lower side of the turnover shaft, the short shaft is in power connection with the turnover shaft through a second belt, a power bevel gear is fixedly arranged at the right end of the short shaft, and a, the driven bevel gear is meshed with the power bevel gear.
7. The automatic anti-infective drug toxicity testing apparatus of claim 6, wherein: the grinding chamber with it is equipped with swing gear to rotate between the dissolution chamber, swing gear downside the swing motor has been inlayed to the main part internal solid, swing motor's top power is connected with power gear, power gear with swing gear meshing design, swing motor can just reverse the rotation, both ends all have set firmly the back shaft about the abrasive disc, the right side the back shaft with swing gear normal running fit, it is left set firmly driven gear in the periphery of back shaft, driven gear can with upset gear engagement.
8. The automatic anti-infective drug toxicity testing apparatus of claim 7, wherein: the downside intercommunication in dissolving the chamber is equipped with the waste water chamber, the waste water chamber is used for depositing sewage, the waste water chamber with dissolve and be equipped with between the chamber can with dissolve chamber bottom confined baffle, grind and set firmly the water jet that can spray water on the diapire in chamber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202010488201.6A CN111596019A (en) | 2020-06-02 | 2020-06-02 | Anti-infective drug toxicity automatic detection equipment |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010488201.6A CN111596019A (en) | 2020-06-02 | 2020-06-02 | Anti-infective drug toxicity automatic detection equipment |
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| CN111596019A true CN111596019A (en) | 2020-08-28 |
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| CN202010488201.6A Withdrawn CN111596019A (en) | 2020-06-02 | 2020-06-02 | Anti-infective drug toxicity automatic detection equipment |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112853665A (en) * | 2021-01-08 | 2021-05-28 | 佛山市佑隆印染有限公司 | Singeing device used before fabric printing and dyeing and control method thereof |
| CN114280285A (en) * | 2021-12-30 | 2022-04-05 | 生态环境部南京环境科学研究所 | Device for testing acute toxicity of rice disease and pest control agent to shellfish aquatic organisms |
| CN115999738A (en) * | 2023-03-28 | 2023-04-25 | 山东中医药大学附属医院 | Skin medicine research laboratory equipment |
-
2020
- 2020-06-02 CN CN202010488201.6A patent/CN111596019A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112853665A (en) * | 2021-01-08 | 2021-05-28 | 佛山市佑隆印染有限公司 | Singeing device used before fabric printing and dyeing and control method thereof |
| CN112853665B (en) * | 2021-01-08 | 2022-03-29 | 佛山市佑隆印染有限公司 | Singeing device used before fabric printing and dyeing and control method thereof |
| CN114280285A (en) * | 2021-12-30 | 2022-04-05 | 生态环境部南京环境科学研究所 | Device for testing acute toxicity of rice disease and pest control agent to shellfish aquatic organisms |
| CN115999738A (en) * | 2023-03-28 | 2023-04-25 | 山东中医药大学附属医院 | Skin medicine research laboratory equipment |
| CN115999738B (en) * | 2023-03-28 | 2023-09-29 | 山东中医药大学附属医院 | Skin medicine research laboratory equipment |
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Application publication date: 20200828 |