CN111557981A - Externally-applied spray type eye drop for relieving visual fatigue - Google Patents
Externally-applied spray type eye drop for relieving visual fatigue Download PDFInfo
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- CN111557981A CN111557981A CN201910115283.7A CN201910115283A CN111557981A CN 111557981 A CN111557981 A CN 111557981A CN 201910115283 A CN201910115283 A CN 201910115283A CN 111557981 A CN111557981 A CN 111557981A
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- vitamin
- eye drop
- relieving
- palmitate
- visual fatigue
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- 208000003464 asthenopia Diseases 0.000 title claims abstract description 28
- 239000003889 eye drop Substances 0.000 title claims abstract description 27
- 239000007921 spray Substances 0.000 title claims abstract description 10
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims abstract description 36
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 34
- VYGQUTWHTHXGQB-UHFFFAOYSA-N Retinol hexadecanoate Natural products CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229940108325 retinyl palmitate Drugs 0.000 claims abstract description 18
- 235000019172 retinyl palmitate Nutrition 0.000 claims abstract description 18
- 239000011769 retinyl palmitate Substances 0.000 claims abstract description 18
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 17
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 17
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229930003270 Vitamin B Natural products 0.000 claims abstract description 17
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 17
- 229940116229 borneol Drugs 0.000 claims abstract description 17
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 17
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000003814 drug Substances 0.000 claims abstract description 17
- 235000019156 vitamin B Nutrition 0.000 claims abstract description 17
- 239000011720 vitamin B Substances 0.000 claims abstract description 17
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 17
- 239000011718 vitamin C Substances 0.000 claims abstract description 17
- 244000035851 Chrysanthemum leucanthemum Species 0.000 claims abstract description 13
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims abstract description 13
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 13
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 13
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 13
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 13
- 230000000694 effects Effects 0.000 claims abstract description 13
- 235000015463 Lycium carolinianum Nutrition 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 230000004438 eyesight Effects 0.000 claims abstract description 6
- 206010013774 Dry eye Diseases 0.000 claims abstract description 3
- 230000002195 synergetic effect Effects 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 15
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- 239000000706 filtrate Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 241000628997 Flos Species 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 230000004399 eye closure Effects 0.000 claims description 5
- 210000000744 eyelid Anatomy 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 210000000582 semen Anatomy 0.000 claims description 5
- 239000011780 sodium chloride Substances 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 238000003860 storage Methods 0.000 claims description 5
- 239000000047 product Substances 0.000 claims description 3
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 206010010726 Conjunctival oedema Diseases 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 208000012886 Vertigo Diseases 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 231100000889 vertigo Toxicity 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 229930003347 Atropine Natural products 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 description 1
- 206010023644 Lacrimation increased Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 235000015468 Lycium chinense Nutrition 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 208000001140 Night Blindness Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010034960 Photophobia Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- BGDKAVGWHJFAGW-UHFFFAOYSA-N Tropicamide Chemical compound C=1C=CC=CC=1C(CO)C(=O)N(CC)CC1=CC=NC=C1 BGDKAVGWHJFAGW-UHFFFAOYSA-N 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 229960000396 atropine Drugs 0.000 description 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000004317 lacrimation Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 230000004379 myopia Effects 0.000 description 1
- 208000001491 myopia Diseases 0.000 description 1
- ALWKGYPQUAPLQC-UHFFFAOYSA-N neostigmine Chemical compound CN(C)C(=O)OC1=CC=CC([N+](C)(C)C)=C1 ALWKGYPQUAPLQC-UHFFFAOYSA-N 0.000 description 1
- 229960002362 neostigmine Drugs 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 229960003471 retinol Drugs 0.000 description 1
- 235000020944 retinol Nutrition 0.000 description 1
- 239000011607 retinol Substances 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 229960004791 tropicamide Drugs 0.000 description 1
- 150000002266 vitamin A derivatives Chemical class 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention provides an external spray type eye drop for relieving visual fatigue, which comprises the following raw materials in parts by weight: 40-60 g of cassia seed, 40-60 g of boxthorn leaf, 20-30 g of wild chrysanthemum flower, 0.2-0.5 mg of vitamin A palmitate, 20-30 mg of vitamin B, 10-20 mg of vitamin C and 1-3 g of borneol. The invention inherits the traditional Chinese medicine concept, adopts pure natural raw materials, has reasonable compatibility and synergistic action, and is developed into a safe, efficient and high-quality product. The eye drop has the effects of clearing heat, improving eyesight, relieving eye fatigue, eye dryness and ache, and relieving eye fatigue, and has the advantages of small side effect, safety, effectiveness and convenient use.
Description
Technical Field
The invention belongs to the field of medicines, and particularly relates to an external spray type eye drop for relieving visual fatigue.
Technical Field
At present, electronic products are various in variety, the use frequency of people is higher and higher, particularly, the use frequency of mobile phones, computers and televisions is high, and the eyes of people are naturally injured to a certain degree. Research data indicate that in recent years, more and more patients have had myopic eyes. These factors determine the eye to be the most prone to aging and fatigue. The existing asthenopia treatment methods have a variety of drug treatments, including atropine, neostigmine, tropicamide and the like, but have certain side effects and are easy to relapse.
Therefore, how to develop a preparation for rapidly relieving asthenopia is a realistic problem.
Disclosure of Invention
The invention aims to provide an externally-applied spray type eye drop for relieving visual fatigue, which inherits the traditional Chinese medicine concept, has obvious effect of improving myopia, and is safe and effective.
In order to achieve the aim, the invention provides an external spray type eye drop for relieving visual fatigue, which comprises the following raw materials in parts by weight: 40-60 g of cassia seed, 40-60 g of boxthorn leaf, 20-30 g of wild chrysanthemum flower, 0.2-0.5 mg of vitamin A palmitate, 20-30 mg of vitamin B, 10-20 mg of vitamin C and 1-3 g of borneol.
Preferably, the formula comprises 40 g of cassia seed, 40 g of boxthorn leaf, 20 g of wild chrysanthemum flower, 0.2 mg of vitamin A palmitate, 20 mg of vitamin B, 10 mg of vitamin C and 1 g of borneol.
Preferably, 50 g of cassia seed, 50 g of boxthorn leaf, 25 g of wild chrysanthemum flower, 0.35 mg of vitamin A palmitate, 25 mg of vitamin B, 15 mg of vitamin C and 1.5 g of borneol.
Preferably, the formula comprises 60 g of cassia seed, 60 g of boxthorn leaf, 30 g of wild chrysanthemum flower, 0.5 mg of vitamin A palmitate, 30 mg of vitamin B, 20 mg of vitamin C and 3 g of borneol.
Further, the invention relates to an externally-applied spray-type eye drop for relieving visual fatigue, which comprises the following steps:
1) putting semen Cassiae, Lycii folium and flos Chrysanthemi Indici into a casserole with water, decocting with slow fire for 4-6 hr, cooling, filtering, and collecting filtrate;
2) adding vitamin A palmitate, vitamin B and vitamin C into the filtrate obtained in the step 1, adding borneol and sodium chloride, stirring uniformly, adjusting the pH value to 6-7, and sterilizing to obtain a liquid medicine for later use;
3) and (3) loading the liquid medicine obtained in the step (2) into a liquid storage part, and then atomizing by using an atomizer to obtain the eye drop. The eye closure is sprayed on eyelid, water can quickly infiltrate into eyes to moisten eyes, 3-4 times per day, 1-2 times per time, and the eyes are closed and the spirit is maintained for about 1 minute.
The main components are explained below:
cassia seed: has the effects of clearing heat, improving eyesight, moistening intestines and relaxing bowels. Can be used for treating conjunctival congestion, swelling and pain, photophobia, lacrimation, dim eyesight, headache, vertigo, and constipation due to intestinal dryness.
Wolfberry leaf: has the effects of tonifying deficiency, replenishing vital essence, clearing heat, quenching thirst, dispelling wind, improving eyesight, promoting fluid production and tonifying liver. Can be used for treating lumbago due to asthenia, fever, polydipsia, conjunctival congestion, nebula, night blindness, metrorrhagia, leukorrhagia, and sore and swelling due to toxic heat.
Wild chrysanthemum flower: has effects of clearing away heat and toxic materials. It can be used for treating carbuncle, cellulitis, furuncle, sore throat, conjunctival congestion, swelling and pain, headache, vertigo, and pathogenic microorganism resisting and antiinflammatory effects.
Vitamin a palmitate: is a derivative of vitamin A, is easily absorbed by skin, and then is converted into retinol, which can accelerate skin metabolism and promote cell proliferation.
The substantive characteristics and the remarkable progress of the invention are as follows:
the invention provides an externally-applied spray-type eye drop for relieving visual fatigue, which inherits the traditional Chinese medicine concept, adopts pure natural raw materials, and is developed into a safe, efficient and high-quality product by reasonable compatibility and synergistic action. The eye drop has the effects of clearing heat, improving eyesight, relieving eye fatigue, eye dryness and ache, and relieving eye fatigue, and has the advantages of small side effect, safety, effectiveness and convenient use.
Detailed Description
The technical scheme of the invention is further illustrated by the following specific examples.
Example 1
The invention relates to an external spray type eye drop for relieving visual fatigue, which comprises the following raw materials in parts by weight: 40 g of cassia seed, 40 g of boxthorn leaf, 20 g of wild chrysanthemum flower, 0.2 mg of vitamin A palmitate, 20 mg of vitamin B, 10 mg of vitamin C and 1 g of borneol.
Further, the invention relates to an externally-applied spray-type eye drop for relieving visual fatigue, which comprises the following steps:
1) putting semen Cassiae, Lycii folium and flos Chrysanthemi Indici into a casserole with water, decocting with slow fire for 4-6 hr, cooling, filtering, and collecting filtrate;
2) adding vitamin A palmitate, vitamin B and vitamin C into the filtrate obtained in the step 1, adding borneol and sodium chloride, stirring uniformly, adjusting the pH value to 6-7, and sterilizing to obtain a liquid medicine for later use;
3) and (3) loading the liquid medicine obtained in the step (2) into a liquid storage part, and then atomizing by using an atomizer to obtain the eye drop. The eye closure is sprayed on eyelid, water can quickly infiltrate into eyes to moisten eyes, 3-4 times per day, 1-2 times per time, and the eyes are closed and the spirit is maintained for about 1 minute.
Example 2
The invention provides an external spray type eye drop for relieving visual fatigue, which comprises the following raw materials in parts by weight: 50 g of cassia seed, 50 g of boxthorn leaf, 25 g of wild chrysanthemum flower, 0.35 mg of vitamin A palmitate, 25 mg of vitamin B, 15 mg of vitamin C and 1.5 g of borneol.
Further, the invention relates to an externally-applied spray-type eye drop for relieving visual fatigue, which comprises the following steps:
1) putting semen Cassiae, Lycii folium and flos Chrysanthemi Indici into a casserole with water, decocting with slow fire for 4-6 hr, cooling, filtering, and collecting filtrate;
2) adding vitamin A palmitate, vitamin B and vitamin C into the filtrate obtained in the step 1, adding borneol and sodium chloride, stirring uniformly, adjusting the pH value to 6-7, and sterilizing to obtain a liquid medicine for later use;
3) and (3) loading the liquid medicine obtained in the step (2) into a liquid storage part, and then atomizing by using an atomizer to obtain the eye drop. The eye closure is sprayed on eyelid, water can quickly infiltrate into eyes to moisten eyes, 3-4 times per day, 1-2 times per time, and the eyes are closed and the spirit is maintained for about 1 minute.
Example 3
The invention provides an external spray type eye drop for relieving visual fatigue, which comprises the following raw materials in parts by weight: 60 g of cassia seed, 60 g of boxthorn leaf, 30 g of wild chrysanthemum flower, 0.5 mg of vitamin A palmitate, 30 mg of vitamin B, 20 mg of vitamin C and 3 g of borneol.
Further, the invention relates to an externally-applied spray-type eye drop for relieving visual fatigue, which comprises the following steps:
1) putting semen Cassiae, Lycii folium and flos Chrysanthemi Indici into a casserole with water, decocting with slow fire for 4-6 hr, cooling, filtering, and collecting filtrate;
2) adding vitamin A palmitate, vitamin B and vitamin C into the filtrate obtained in the step 1, adding borneol and sodium chloride, stirring uniformly, adjusting the pH value to 6-7, and sterilizing to obtain a liquid medicine for later use;
3) and (3) loading the liquid medicine obtained in the step (2) into a liquid storage part, and then atomizing by using an atomizer to obtain the eye drop. The eye closure is sprayed on eyelid, water can quickly infiltrate into eyes to moisten eyes, 3-4 times per day, 1-2 times per time, and the eyes are closed and the spirit is maintained for about 1 minute.
The invention inherits the traditional Chinese medicine concept, has obvious effect of relieving visual fatigue, small side effect, safety, effectiveness and convenient use.
Claims (5)
1. The invention provides an external spray type eye drop for relieving visual fatigue, which comprises the following raw materials in parts by weight: 40-60 g of cassia seed, 40-60 g of boxthorn leaf, 20-30 g of wild chrysanthemum flower, 0.2-0.5 mg of vitamin A palmitate, 20-30 mg of vitamin B, 10-20 mg of vitamin C and 1-3 g of borneol. The invention inherits the traditional Chinese medicine concept, adopts pure natural raw materials, has reasonable compatibility and synergistic action, and is developed into a safe, efficient and high-quality product. The eye drop has the effects of clearing heat, improving eyesight, relieving eye fatigue, eye dryness and ache, and relieving eye fatigue, and has the advantages of small side effect, safety, effectiveness and convenient use.
2. The externally-applied spray-type eye drop for relieving visual fatigue of claim 1, which comprises the following raw materials in parts by weight: 40 g of cassia seed, 40 g of boxthorn leaf, 20 g of wild chrysanthemum flower, 0.2 mg of vitamin A palmitate, 20 mg of vitamin B, 10 mg of vitamin C and 1 g of borneol.
3. The externally-applied spray-type eye drop for relieving visual fatigue of claim 1, which comprises the following raw materials in parts by weight: 50 g of cassia seed, 50 g of boxthorn leaf, 25 g of wild chrysanthemum flower, 0.35 mg of vitamin A palmitate, 25 mg of vitamin B, 15 mg of vitamin C and 1.5 g of borneol.
4. The externally-applied spray-type eye drop for relieving visual fatigue of claim 1, which comprises the following raw materials in parts by weight: 60 g of cassia seed, 60 g of boxthorn leaf, 30 g of wild chrysanthemum flower, 0.5 mg of vitamin A palmitate, 30 mg of vitamin B, 20 mg of vitamin C and 3 g of borneol.
5. The externally applied spray-on eye drop for relieving visual fatigue of claim 1, which comprises the steps of:
1) putting semen Cassiae, Lycii folium and flos Chrysanthemi Indici into a casserole with water, decocting with slow fire for 4-6 hr, cooling, filtering, and collecting filtrate;
2) adding vitamin A palmitate, vitamin B and vitamin C into the filtrate obtained in the step 1, adding borneol and sodium chloride, stirring uniformly, adjusting the pH value to 6-7, and sterilizing to obtain a liquid medicine for later use;
3) and (3) loading the liquid medicine obtained in the step (2) into a liquid storage part, and then atomizing by using an atomizer to obtain the eye drop. The eye closure is sprayed on eyelid, water can quickly infiltrate into eyes to moisten eyes, 3-4 times per day, 1-2 times per time, and the eyes are closed and the spirit is maintained for about 1 minute.
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| CN113425637A (en) * | 2021-06-10 | 2021-09-24 | 天津科技大学 | Lycium ruthenicum eyesight improving nano eye cream for children and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113425637A (en) * | 2021-06-10 | 2021-09-24 | 天津科技大学 | Lycium ruthenicum eyesight improving nano eye cream for children and preparation method thereof |
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