CN111481283B - Preparation method of 3D printer surface guide plate - Google Patents

Preparation method of 3D printer surface guide plate Download PDF

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Publication number
CN111481283B
CN111481283B CN202010315803.1A CN202010315803A CN111481283B CN 111481283 B CN111481283 B CN 111481283B CN 202010315803 A CN202010315803 A CN 202010315803A CN 111481283 B CN111481283 B CN 111481283B
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guide plate
body surface
printer
positioning
model
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CN111481283A (en
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张梅刃
黄涛生
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Zhuhai Hospital Of Guangdong Hospital Of Traditional Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/90Guides therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30Auxiliary operations or equipment
    • B29C64/386Data acquisition or data processing for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30Auxiliary operations or equipment
    • B29C64/386Data acquisition or data processing for additive manufacturing
    • B29C64/393Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • B33Y50/02Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3405Needle locating or guiding means using mechanical guide means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • A61B2017/3413Needle locating or guiding means guided by ultrasound

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention relates to a manufacturing method of a medical tool, in particular to a manufacturing method of a 3D printer surface guide plate. The method comprises collecting data, reconstructing a 3D model with a locating spacer with the help of three-dimensional design software in a data processing device; importing the obtained 3D model into three-dimensional modeling software through an STL format file, and firstly establishing an original body surface substrate guide plate on the body surface around the model metal gasket; the original body surface guide plate is reintroduced into the three-dimensional design software through the STL format file, and at least 2 positioning holes are designed in the positions of the central holes of the two metal gaskets on the original body surface substrate guide plate; confirm the position of guide pin sleeve in order to form 3D body surface baffle model on three-dimensional modeling, 3D body surface baffle model channels into the 3D printer, prints and forms 3D printer body surface baffle. The guide plate can be used for actively improving the positioning accuracy, and the positioning accuracy can be effectively improved by using more positioning points, so that the accuracy and the success rate of the operation are improved.

Description

Preparation method of 3D printer surface guide plate
Technical Field
The invention relates to a manufacturing method of a medical tool, in particular to a manufacturing method of a 3D printer surface guide plate for inserting or taking out a screw.
Background
Preoperative planning is very important for operations with high risk and great difficulty. Conventionally, data of a patient is acquired through imaging equipment such as CT and Magnetic Resonance Imaging (MRI), which is the basis for pre-planning of a doctor's operation, but the acquired medical image is two-dimensional, and in clinical medical operations, it is difficult for the doctor to accurately grasp the accuracy of the operation, which results in many failed operations. Particularly, under the condition that the bone blocks need to be accurately connected when screws need to be placed in the bone surgery, the two-dimensional data is difficult to perform the accurate surgery.
Disclosure of Invention
Aiming at the technical problems, the invention provides a method for manufacturing a 3D printer surface guide plate for inserting or taking out screws, which aims to greatly improve the precision of the operation for inserting or taking out the screws.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: a preparation method of a 3D printer surface guide plate comprises the following steps,
a. adhering at least 2 annular metal gaskets to the body surface near the screw for placing or taking out, using the metal gaskets to perform the function of positioning anchor points, using a marking pen to mark the position of the annular gaskets on the body surface, and carrying out CT scanning on the limb with the gaskets to obtain limb CT data;
b. b, importing the limb CT data obtained in the step a into data processing equipment according to a DICOM mode, and reconstructing a 3D limb model with a positioning gasket under the help of E3D software in the data processing equipment; the DICOM mode refers to medical digital imaging and communication, and is an international standard for medical images and related information;
c. b, importing the 3D limb model obtained in the step b into three-dimensional modeling software, such as Geomagic Wrap software, through an STL format file, and establishing an original body surface base guide plate on the body surface around the 3D limb model positioning pad;
d. the method comprises the steps that an original body surface base guide plate is led into E3D software again through an STL format file, and a positioning hole is formed in the position of a gasket center hole of the original body surface base guide plate; E3D software is also a three-dimensional design software.
e. D, determining the position of a guide pin sleeve on the original body surface base guide plate in the step D to form a 3D body surface guide plate model, wherein the guide pin sleeve is determined by the position and the direction of the screw which is put in or taken out and a needle feeding point;
f. and e, guiding the 3D body surface guide plate model obtained in the step e into a 3D printer, and printing to form the 3D printer body surface guide plate for the screw placing or taking-out operation. The printing material is polylactic acid (PLA), is a novel bio-based and renewable biodegradable material, and is most suitable as a construction material.
Further: in the preparation method of the 3D printer surface guide plate, the size of the positioning hole in the step D is the same as that of the central hole of the gasket, and the aperture is 4 +/-1 mm. The guide pin sleeve is consistent with the position and the direction of a screw to be placed in or taken out and the longitudinal axis of a needle feeding point. The inner diameter of the guide pin sleeve is 2.0 +/-1 mm, and the outer diameter of the guide pin sleeve is 3.5 +/-1 mm.
The E3D software and the Geomagic Wrap software mentioned in the invention are all the software commonly used by those skilled in the art.
Compared with the prior art, the invention virtualizes the three-dimensional structure of the to-be-constructed body by using a computer aided design technology through the assistance of an image technology, such as data of CT, MRI and the like, and then establishes the entity layer by using corresponding materials, thereby having the advantages of high precision, high construction speed, capability of realizing the manufacturing according to requirements and the like, and the advantages of individuation, precision, remote and the like, and being particularly suitable for the application in the medical field. The 3D printer can directly print out the three-dimensional model, both can assist the doctor to carry out accurate operation planning, promote the success rate of operation, make things convenient for again that doctor and patient carry out audio-visual communication with regard to the operation scheme. In addition, even if treatment fails, 3D printing can provide traceability for both doctors and patients. The invention has the following beneficial technical effects: 1. the active positioning can be used in any place needing positioning, a plane can be positioned only by actively sticking two or more gaskets, and the position of a three-dimensional space can be positioned through the positioning plane without being limited by an inherent surface, such as a bone surface or a skin surface; the device is not limited by fixed bone (human body) marks, and also is free from the hard limitation of bone surface positioning, can be used in any place, and can also be used in other subjects, such as puncture biopsy and puncture hematoma drainage which need b-ultrasonic positioning or ct positioning. 2. The application on the body surface is equal to that the application in the body is greatly expanded, tissues are not required to be exposed, loss is reduced, bleeding is reduced, perspective and the like are reduced, the guide plate is not required to be contacted with the tissues in the body, iatrogenic infection is prevented, and the application range of the guide plate is expanded. 3. The positioning accuracy can be actively improved, and the positioning accuracy can be effectively improved by using more positioning points.
Detailed Description
In order to make those skilled in the art better understand the technical solution of the present invention, the technical solution of the present invention is further explained below.
Example 1:
patient 1: female, 49 years old, in 6 late months of 2019, when going on mountain and walking, the right foot swelling and pain activities are limited due to careless 'sprain' and the conservative treatment such as plaster fixation and local symptomatic treatment is given when the X-ray prompt the fracture of the 2 nd to 4 th metatarsal bone of the right foot, after 7 weeks of treatment, the conscious swelling and pain activities are limited and not relieved, and then the female can go to a doctor again and check to diagnose 'the Lisfranec fracture dislocation' of the right foot and then take the patient to a hospital for further treatment. The method comprises the steps of perfecting examination after hospital admission, perfecting examination of a right foot MRI/CT/foot load bearing positive lateral position sheet and the like, clearly diagnosing, performing 'right foot Lisfranc fracture dislocation cutting reduction steel plate screw internal fixation and Lisfranc screw implantation under a 3D printing body surface guide plate' on the lumbar and rigid joint anesthesia about 8 weeks after injury, successfully implanting the Lisfranc screw once in the operation, enabling the position of the implanted screw to be matched with the optimal position simulated by a preoperative computer, achieving good postoperative opening healing, performing local anesthesia downlink right foot Lisfranc screw removal for 4 months after the operation, and ensuring that a postoperative patient can recover well and is still subjected to regular follow-up at present.
The Lisfranec screw implantation method with the body surface gasket positioning and 3D printer body surface guide plate assistance comprises the following steps:
body surface positioning and CT scanning reconstruction
And 2 annular metal gaskets are pasted on the body surface near the first metatarsal wedge joint on the inner side of the instep after hospital admission (the optimal needle inserting point of a Lisfranec screw on the inner side of the right instep is avoided, the metal gaskets are used for performing the function of positioning anchor points, marking the positions of the annular gaskets on the body surface by using a marking pen, and carrying out CT scanning and 3D reconstruction by carrying the positioned gaskets on the body surface.
Design of 3D body surface guide plate
And 1, storing the CT data in an optical disk according to a DICOM mode, and importing the data into a computer for continuous processing. With the help of e3D software, a right foot 3D model with a positioning pad is reconstructed.
2. And importing the right-foot 3D model into Geomagic Wrap software through an STL format file, and establishing an original body surface substrate guide plate (the range includes the positioning pad holes) on the body surface around the positioning pad of the right-foot model.
3. And (4) establishing an original body surface guide plate by the Geomagic Wrap software, and reintroducing the original body surface guide plate into the e3D software through the STL format file. 2 positioning holes are designed at the positions of the two gasket holes of the original body surface substrate guide plate, and the sizes of the holes and the sizes of the gasket holes are the same and are 4mm.
4. The optimum position and direction of the Lisfranc screw to be placed and the needle feeding point are designed and observed from a three-dimensional angle, the guide pin sleeve on the guide plate can be designed according to the optimum position and direction of the Lisfranc screw to be placed and the needle feeding point longitudinal axis, the longitudinal directions of the guide pin sleeve and the Lisfranc screw are completely consistent, the inner diameter can be designed to be 2.0mm, the outer diameter is designed to be 3.5mm, and the guide pin sleeve guide plate and the body surface substrate guide plate are combined to establish a final guide plate, so that the personalized body surface guide plate is prepared.
5. And guiding the designed body surface guide plate into a 3D printer for printing (PLA material) to obtain the 3D printer body surface guide plate, and performing plasma disinfection before operation for later use.
Third, the operation skill and procedure
1. The patient lies on the back, the waist is numb, the routine disinfection of right lower limb is spread the piece of cloth;
2. performing longitudinal incision on the back side between the first metatarsus and the second metatarsus, wherein the length of the longitudinal incision is about 8cm, the longitudinal incision enters layer by layer, tissues between the first metatarsus and the second metatarsus are exposed, scar tissues and hyperplastic tissues between the metatarsus are cleaned, the second metatarsus which is going out of position and is dislocated to the back is reset, and the second metatarsus is temporarily fixed by using a tissue clamp; c, the first metatarsal gap is recovered to be normal when the C-arm machine looks through, and the second metatarsal wedge joint is fixed by the miniature steel plate;
3. after the positioning holes on the 3D body surface guide plate which is well sterilized are completely overlapped with the marking holes on the instep body surface
4. Placing a guide pin hole with the diameter of 1.5mm into a guide pin hole of a 3D body surface guide plate, observing that the position of the guide pin is completely consistent with the position of a designed Lisfranec screw before operation, placing a guide pin drill hole with the diameter of 1.5mm into a hollow drill with the diameter of 2.5mm, removing the guide pin, measuring the length of the screw to be placed, and placing a locking screw with the diameter of 2.7mm into the hollow drill with the diameter of 2.5 mm;
5. the first metatarsal bone gap is confirmed to be recovered to be normal through fluoroscopy again, the length of the position where the screw is placed is proper, and the position is completely consistent with the preoperative 3D design; 6. the surgical port was cleaned, sutured, and the Lisfranc screw incision was made approximately 0.5cm, which took about 10 minutes to insert the Lisfranc screw.
Fourth, after-operation treatment
Performing conventional treatment after operation, using a preventive antibacterial agent for 48 hours, rechecking an X-ray film and a CT (computed tomography) after the second day after the operation, starting muscle function exercise and non-weight-bearing walking of the affected limb after the second day after the operation, removing stitches of an operation opening for 2 weeks after the operation, removing Lisfrac screws after 4 months after the operation, walking the affected limb gradually and under a weight, and scoring AOFAS for 86 without other discomfort after the last half year of the operation.
Example 2
Patient 2: for male, 49 years old, the left double ankle fracture was treated in the hospital before one year, and the external ankle steel plate was reduced by cutting and fixed in the hollow screw of the internal ankle. The fracture of hollow nail guide pin takes place in the art, lead to one section cracked guide pin to remain in the bone, consider that the fracture guide pin is in shin bone marrow cavity, it is big to take out the degree of difficulty in the art, and cause the sclerotin to destroy easily, influence union of fracture, agree with the patient in the art and temporarily do not take out cracked guide pin earlier, take out again when waiting for the fixed removal of union internal fixation and remain the guide pin, the postoperative patient recovers well, regular follow-up visit, the special circumstances is not complained during, postoperative one year reexamination piece suggestion fracture has healed, it takes out with remaining the guide pin to pass through fixed the removal in hospital.
Body surface positioning and CT scanning reconstruction
Remain behind the hospital near the shin bone distal end anterolateral body surface subsides 2 annular metal gasket of guide pin, carry out the effect of location anchor point with metal gasket to with the marker pen in the position of the good annular gasket of body surface mark, take the good gasket row CT scan of body surface location and 3D to rebuild.
Design of 3D body surface guide plate
And 1, storing the CT data in an optical disk according to a DICOM mode, and importing the data into a computer for continuous processing. With the aid of e3D software, a 3D model of the left tibiofibula and left calf with locating shims was reconstructed.
2. And importing the left calf 3D model into Geomagic Wrap software through an STL format file, and establishing an original body surface substrate guide plate (the range includes the positioning pad holes) on the body surface around the positioning pad of the left calf model.
3. And (4) establishing an original body surface guide plate by the Geomagic Wrap software, and reintroducing the original body surface guide plate into the e3D software through the STL format file. 2 locating holes are designed at the positions of the two gasket holes of the original body surface substrate guide plate, and the size of each hole is 3mm as same as that of each gasket hole.
4. Observing the position and the direction of the residual guide pin from a three-dimensional angle, designing the sleeve of the guide plate according to the longitudinal axis of the residual guide pin, completely keeping the longitudinal direction of the guide pin sleeve and the residual guide pin, designing the inner diameter of the sleeve to be 2.2mm and the outer diameter of the sleeve to be 3.5mm, and establishing the final guide plate after combining the sleeve guide plate and the body surface substrate guide plate, so that the personalized body surface guide plate is prepared.
5. And (3) guiding the designed guide plate into a 3D printer for printing (PLA material) to obtain a 3D printer surface guide plate, and performing plasma disinfection.
Third, surgical technique and procedure
1. The patient lies on the back, the waist is numb, the conventional disinfection of left lower limb is spread the piece of cloth; .
2. Inserting a positioning kirschner wire into the sterilized 3D printing body guide plate to reach the bone surface;
3. cutting the skin, opening subcutaneous tissues, pushing periosteum open, and sleeving a trephine from a kirschner wire;
4. windowing cortical bone, taking out the broken needle at the same time, and plugging the windowed bone back to the original position;
5. the operation mouth is cleaned and sutured, the incision is about 0.5cm (1 h), the process takes less than 5 minutes, and fluoroscopy is not needed in the operation.
Fourth, after-operation treatment
And performing conventional treatment after the operation, not using a preventive antibacterial agent, rechecking the X-ray film after the operation on the second day, starting the muscle function exercise of the lower limbs and walking with the weight of the patient on the ground on the second day after the operation, and removing stitches of the operation opening for 2 weeks after the operation without complaints.

Claims (4)

1. A preparation method of a 3D printer surface guide plate is characterized by comprising the following steps: comprises the following steps of (a) carrying out,
a. attaching at least 2 annular metal gaskets to the body surface near the screw to be placed or taken out, using the metal gaskets to perform the function of positioning anchor points, using a marking pen to mark the positions of the metal gaskets on the body surface, using the metal gaskets at any position needing positioning, positioning a plane only by actively attaching at least 2 metal gaskets, and obtaining limb CT data by CT scanning of a limb with the metal gaskets;
b. b, importing the limb CT data obtained in the step a into data processing equipment according to a DICOM mode, and reconstructing a 3D limb model with a metal gasket under the help of E3D software in the data processing equipment;
c. b, importing the 3D limb model obtained in the step b into three-dimensional modeling software through an STL format file, and establishing an original body surface substrate guide plate on the body surface around the metal gasket of the 3D limb model;
d. the method comprises the following steps of re-importing an original body surface base guide plate into E3D software through an STL format file, wherein a positioning hole is formed in the center hole of a metal gasket of the original body surface base guide plate;
e. d, determining the position of a guide pin sleeve on the original body surface base guide plate in the step D to form a 3D body surface guide plate model, wherein the guide pin sleeve is determined by the position and the direction of the screw which is put in or taken out and a needle feeding point;
f. and e, guiding the 3D body surface guide plate model obtained in the step e into a 3D printer, and printing to form the 3D printer body surface guide plate for putting or taking out the screw.
2. The method for preparing a 3D printer surface guide plate according to claim 1, wherein the method comprises the following steps: and d, the size of the positioning hole in the step d is the same as that of the central hole of the metal gasket, and the aperture is 4 +/-1 mm.
3. The method for preparing a 3D printer surface guide plate according to claim 1, wherein the method comprises the following steps: the guide pin sleeve is consistent with the position and the direction of the screw put in or taken out and the longitudinal axis of the needle feeding point.
4. The method for preparing a 3D printer surface guide plate according to claim 3, wherein: the inner diameter of the guide pin sleeve is 2.0 +/-1 mm, and the outer diameter of the guide pin sleeve is 3.5 +/-1 mm.
CN202010315803.1A 2020-04-21 2020-04-21 Preparation method of 3D printer surface guide plate Active CN111481283B (en)

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CN108742822A (en) * 2018-04-04 2018-11-06 广东医科大学附属医院 A kind of preparation method of navigation module for the blocking nail implantation of fracture of tibia Medullary fixation
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