CN111467369A

CN111467369A - Method for preventing and treating respiratory system viral diseases or lung diseases in auxiliary manner by water rich in oxidized radicals and application of water rich in oxidized radicals

Info

Publication number: CN111467369A
Application number: CN202010278608.6A
Authority: CN
Inventors: 钟建华; 张文英
Original assignee: Guangzhou Deposon Electric Technology Co ltd
Current assignee: Guangzhou Deposon Electric Technology Co ltd
Priority date: 2020-04-10
Filing date: 2020-04-10
Publication date: 2020-07-31

Abstract

The invention relates to a method for preventing and treating respiratory system viral diseases and lung diseases by using water rich in oxidized radicals and application thereof. The application of the invention is that the patients with lung diseases drink the water rich in oxidized radicals, and the oxygen in the water rich in oxidized radicals is absorbed by a digestive system and enters a blood circulation system to be carried to all parts of the whole body for utilization, so as to compensate the oxygen deficiency caused by the failure of effective ventilation of lung dysfunction caused by the lung diseases. Compared with a respirator and ECMO, drinking the water rich in the oxidized radicals is a cheaper and more convenient oxygen supply mode.

Description

Method for preventing and treating respiratory system viral diseases or lung diseases in auxiliary manner by water rich in oxidized radicals and application of water rich in oxidized radicals

Technical Field

The invention relates to a method for preventing and treating respiratory system viral diseases or lung diseases by using water rich in oxidized radicals and application thereof.

Background

Respiratory viral diseases, typically acute respiratory infections caused by respiratory invasion of viruses, such as coronaviruses, e.g., parainfluenza, present with cough, purulent sputum, high fever, or viral pneumonia, resulting in dyspnea.

The lung is the respiratory organ of the human body and also the important hematopoietic organ of the human body, the interstitium between the alveoli contains rich capillary network, the capillary membrane and the alveoli jointly form a respiratory membrane, and the gas exchange between the blood and the gas in the alveoli can be carried out only through the respiratory membrane. The main function of the lungs is to ventilate, exchange oxygen from the air through the lungs into the blood by breathing, and to expel carbon dioxide from the body.

Lung diseases are most commonly caused by viral and bacterial infections. In other words, some patients with lung diseases may suffer from acute hypoxia and endanger life in cases of severely damaged alveolar tissues and severe respiratory disorders, so that the respiratory function of the patients is maintained by using a ventilator and ECMO (Extracorporeal Membrane Oxygenation), which have low energy and high cost.

Disclosure of Invention

Based on the above, there is a need for a method for preventing and treating respiratory viral diseases and pulmonary diseases with the aid of water rich in oxidized radicals.

The present invention provides a method for prevention and treatment and adjuvant treatment of pulmonary diseases, comprising administering to a subject an effective amount of water enriched in oxidized radicals.

In one embodiment, the administration is oral administration.

In one embodiment, the effect of the oxidized radical rich water in preventing and treating the lung diseases is to absorb oxygen in the oxidized radical rich water through the digestive system so as to supply oxygen to the subject, and the oxygen enters the blood circulation system through the digestive system and is supplied to an aerobic part so as to relieve the hypoxia phenomenon caused by lung infection of the lung disease patients.

In one embodiment, the administration is via respiratory uptake of the oxidized group-enriched water after nebulization.

In one embodiment, the effect of the water rich in the oxidized group in preventing and treating the lung diseases is to directly take the water containing the oxidized group into respiratory tract and lung through the respiratory system, and kill pathogenic microorganisms in the respiratory system, including one or more of bacteria, viruses, fungi, actinomycetes, rickettsia, mycoplasma, chlamydia and spirochete, through the oxidation of the oxidized group in the water containing the oxidized group.

In one embodiment, the oxidizing groups in the oxidizing group-rich water are present in water in a polar molecular state or an ionic state.

In one embodiment, the oxidized group-rich water comprises ozone molecules.

In one embodiment, the oxygenated group-rich water comprises at least one of ozone, hydroxyl radicals, oxygen atoms, and oxygen gas.

In one embodiment, the ozone content in the oxidized group-rich water administered to the subject is 0.1-6 ppm.

The application of the water rich in the oxidized group in preventing and treating respiratory system viral diseases or lung diseases in an auxiliary way.

The invention has the beneficial effects that:

the application of the invention is that the patients with lung diseases drink the water rich in oxidized radicals, and the oxygen in the water rich in oxidized radicals is absorbed by a digestive system and enters a blood circulation system to be carried to all parts of the whole body for utilization, so as to compensate the oxygen deficiency caused by the failure of effective ventilation of lung dysfunction caused by the lung diseases. Compared with a respirator and ECMO, drinking the water rich in the oxidized radicals is a cheaper and more convenient oxygen supply mode.

In addition, the invention provides a scheme for taking water rich in oxidizing groups from respiratory tract, and the oxidizing groups in the water can rapidly kill bacteria and viruses in respiratory system so as to play roles in prevention and adjuvant therapy. The water rich in the oxidation group is harmless to human bodies, is converted into a common water body after being oxidized and killed, and is healthy, green and environment-friendly. In the embodiment, the water rich in the oxidized group is atomized and then taken in through the respiratory tract, so that the water rich in the oxidized group directly acts on the respiratory tract and the lung, the effect is fast, the effect is better, the atomized particles are soft, and the atomized particles have no irritation to nasal cavities and throats.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Respiratory viral diseases are usually acute respiratory tract infections caused by virus invasion through the respiratory system, and pulmonary diseases are most common infections caused by virus and bacteria, and generally enter a human body through oral cavity and nasal cavity to further infect the respiratory system. The respiratory system (e.g., lungs) is the primary site of viral attack and patients manifest predominantly as coughing, respiratory distress from lung infections, and the like. The lung tissue damage caused by infection of pathogenic microorganisms and the like, due to lung pathological changes, cannot be sufficiently ventilated, causes breathing difficulty and even respiratory failure of patients, and even dies of serious conditions due to incapability of spontaneous breathing, that is, some patients with lung diseases almost equal to death due to anoxia under the condition that alveolar tissues are seriously damaged and respiratory disorders are extremely large, so that the respiratory function of the patients needs to be maintained through a ventilator and ECMO (Extracorporeal Membrane Oxygenation), however, the ventilator and ECMO have low energy and high manufacturing cost. Therefore, the invention provides a thought, which can provide oxygen for patients through water rich in oxidizing groups or kill viruses or provide a more convenient and economic way with lower cost so as to relieve the hypoxia phenomenon caused by lung infection.

In one embodiment, the administration is oral administration.

The subject is supplied with Oxygen by drinking the water rich in oxidized radicals having a Dissolved Oxygen content (DO) higher than that of ordinary water, and the Oxygen is absorbed by the digestive system to the aerobic site through the digestive system, and the absorbed Oxygen enters the blood circulation system through the digestive system and is supplied to the aerobic site, so as to relieve the hypoxia phenomenon of the patient with lung diseases caused by lung infection.

Specifically, the OXYGEN-enriched water rich in oxidized radicals is administered to supplement OXYGEN to human body, and reference is made to "OXYGEN ENRICHED WATER and ORA L OXYGEN THERAPY (OXYGEN-enriched water and oral OXYGEN THERAPY)" related to doctor Pakdaman, germany, which mentions that OXYGEN in the OXYGEN-enriched water is absorbed through the following pathway.

Oxygen-enriched water → oral mucosa and capillary vessels of gastrointestinal tract → portal vein → hepatic circulation → systemic circulation → pO in blood₂(Partial Pressure of Oxygen, Partial Pressure of blood Oxygen) → arrival of the target organ via the blood route.

Therefore, the amount of oxygen dissolved in water affects the amount of oxygen absorbed and utilized by the human body, and the amount of oxygen dissolved in the water rich in oxidized radicals becomes the key of the water rich in oxidized radicals.

Table 1 shows the solubility of oxygen in water at various temperatures at 1 standard atmosphere and 20.9% oxygen in air.

TABLE 1

According to the law of gas dissolution, when the pressure is constant, the solubility of the gas is reduced along with the increase of the temperature, because when the temperature is increased, the movement rate of gas molecules is accelerated and the gas molecules are easy to escape from the water surface. And when the temperature is constant, the solubility of the gas increases as the pressure of the gas increases.

It should be understood that in order to increase the dissolved oxygen content in water at a temperature suitable for human consumption, the existing oxygen-enriched water is mixed with oxygen and water under high pressure, so as to increase the solubility of oxygen in water, and achieve oxygen enrichment. However, this method of increasing the content of dissolved oxygen in water has a great disadvantage because the oxygen-enriched water generated by the pressurization mode is communicated with the outside and separated from the high-pressure environment during the use process, and the oxygen in the supersaturated oxygen-enriched water is released again naturally, so that the purpose of "oxygen enrichment" and absorption and utilization by human body can not be achieved.

Therefore, in order to increase the dissolved oxygen content in water, for example, the oxygen in the oxidized group-enriched water of the present invention is present in water in a polar molecular state or an ionic state. It should be understood that since water is a polar solvent and oxygen is a non-polar molecule, the solubility of oxygen in water is limited according to the principle of similar solubility, and polar molecules, ionic species, contribute to the solubility in water, most ionic compounds are polar compounds.

For example, the oxidized group-rich water includes at least one of ozone, hydroxyl radicals, oxygen atoms, and oxygen gas.

In one embodiment, the oxygenated group-rich water comprises ozone, hydroxyl radicals, oxygen atoms, and oxygen. In another embodiment, the oxygenated group-rich water comprises ozone, hydroxyl radicals, and oxygen atoms. In yet another embodiment, the oxidized group-rich water comprises ozone. Ozone is a polar molecule, has a solubility in water greater than that of oxygen according to the principle of similarity and compatibility, and has a solubility in water about 13 times higher than that of oxygen and 25 times higher than that of air under normal temperature and normal pressure. Therefore, the oxidized radical-rich water obtained by dissolving ozone in water has an "oxygen-rich" effect, and is rich in excess oxygen that can be absorbed and utilized by the human body.

The solubility of ozone in water is affected not only by the water temperature and pressure but also by the concentration of ozone gas, and therefore, ozone does not need to be pressurized, and the solubility of ozone can be increased by increasing the ozone concentration, thereby increasing the oxygen content in the water rich in the oxidized group.

For example, in one embodiment, ozone water is provided as the oxidized group-rich water of the present invention.

Table 2 shows the oxygen content data obtained by measuring ozone water (i.e. water rich in oxidized groups) with different concentrations by an oxygen dissolution instrument according to the present invention.

Concentration of ozone water/ppm	Oxygen content/ppm
		0 (pure water)	3.21
1.0	4.87
		2.0	5.39
3.0	5.64

TABLE 2

Wherein ppm (parts per million) is the parts per million concentration.

In one embodiment, the ozone content in the ozonated water (i.e., the oxidized group-rich water) administered to the subject is 0.1-6 ppm.

For example, the ozone content in the oxidized group-rich water administered to the subject is 0.1ppm, for example, the ozone content in the oxidized group-rich water administered to the subject is 1.0ppm, for example, the ozone content in the oxidized group-rich water administered to the subject is 2.0ppm, for example, the ozone content in the oxidized group-rich water administered to the subject is 3.0ppm, which is not redundantly described in this example.

The invention also provides application of the water rich in the oxidized group in prevention and treatment and adjuvant therapy of lung diseases.

The invention is applied to the treatment of patients with lung diseases by drinking the water rich in oxidized radicals (ozone water), oxygen in the water rich in oxidized radicals is absorbed by a digestive system and enters a blood circulation system to be carried to all parts of the whole body for utilization, so as to compensate oxygen deficiency caused by the failure of effective ventilation of lung dysfunction caused by lung diseases. Compared with a respirator and ECMO, drinking the water rich in the oxidized radicals is a cheaper and more convenient oxygen supply mode.

Wherein the oxygen partial pressure (pO)₂) The pressure generated by the physically dissolved oxygen molecules in the blood, the arterial oxygen partial pressure, depends mainly on the oxygen partial pressure of the inhaled gas and the functional status of the external respiration. The partial pressure of venous blood oxygen may reflect the condition of internal respiration. Therefore, the oxygen partial pressure can be an important parameter for observing the oxygen content in blood.

An experimental data is presented in the paper by doctor Pakdaman, Germany, as shown in Table 3, which is the change in venous blood oxygen partial pressure before and after the experimenter drinks 330ml of oxygen enriched water (oxygen content about 45 mg/L).

TABLE 3

In healthy persons, sufficient oxygen can be obtained through the air, however, persons with lung disease have impaired lung function, possibly resulting in local hypoxia in the body, and studies have shown that the oxygen uptake (%) or extraction efficiency from the air in the body is about 5.6% (left in the lungs), while the oxygen content in the outside air is 20.9%, so that persons with normal breathing parameters when ventilating, retain about 1/4% of the oxygen, and the rest 3/4 are exhaled. Patients with chronic diseases have a faster breathing rate and a lower oxygen extraction rate, and people with chronic diseases breathe about 2.5 times more than normal people. Because the metabolic rate or oxygen demand is about the same, people who are hyperventilating for long periods of time draw less oxygen, most of which is exhaled in critically ill patients, with oxygen retention rates of only a few percent.

As can be seen from the observation of the oxygen partial pressure values in the table 3, the dissolved oxygen content of the blood in vivo can be increased by the oxygen-enriched water, and the partial oxygen supply for the partial deficiency of the lung ventilation function can be compensated by the auxiliary treatment of the lung disease patients by the water rich in the oxidized group. Moreover, people who have hyperventilation for a long time can cause low oxygen retention rate in vivo, further cause lung diseases or other chronic diseases, and drinking water rich in oxidizing radicals can improve the dissolved oxygen content in blood, thereby achieving the purpose of preventing and treating lung diseases/chronic diseases.

The invention also provides another method for preventing and treating viral diseases of respiratory system or pulmonary diseases by using the water rich in the oxidized group, which comprises the step of administering an effective amount of the water rich in the oxidized group to a subject, wherein the administration is carried out by atomizing the water rich in the oxidized group and then taking the atomized water through respiratory tract.

In the embodiment, the effect of the water rich in the oxidized group in preventing and treating the lung diseases is to directly take the water containing the oxidized group into the respiratory tract and the lung through the respiratory system, and oxidize and kill pathogenic microorganisms in the respiratory system, including one or more of bacteria, viruses, fungi, actinomycetes, rickettsia, mycoplasma, chlamydia and spirochete, through the oxidized group in the water containing the oxidized group.

The water rich in oxidizing radicals, that is, the water in which a large amount of oxidizing radicals are dissolved in the water body, wherein the oxidizing radicals are oxidizing radicals, it should be understood that substances with strong oxidizing properties can change the physiological structure and metabolic processes of bacteria to cause the death of bacteria and viruses by denaturing proteins to affect the activity thereof, and therefore, the water rich in oxidizing radicals has the sterilization and disinfection capability.

For example, the oxidized group-rich water includes at least one of ozone, hydroxyl radicals, oxygen atoms, and oxygen gas. For example, the oxidized radical-rich water comprises ozone, for example, the oxidized radical-rich water comprises ozone and hydroxyl radicals.

The invention also provides application of the water rich in the oxidized group in preventing and treating respiratory system viral diseases in an auxiliary way.

The oxidation-reduction potentials of various oxides are shown in table 4, wherein the higher the oxidation-reduction potential, the better the oxidation performance.

TABLE 4

As can be seen from table 4, ozone, hydroxyl radicals, and oxygen atoms have very strong oxidizing properties, and can effectively kill various bacteria and viruses.

It will be appreciated that viral diseases of the respiratory system or pulmonary diseases are typically caused by viral infections, and therefore, this example provides a protocol for the uptake of water from the respiratory tract which is rich in oxidizing groups which rapidly kill bacterial viruses in the respiratory system for prophylactic and therapeutic purposes. The water rich in the oxidation group is harmless to human bodies, is converted into a common water body after being oxidized and killed, and is healthy, green and environment-friendly. In the embodiment, the water rich in the oxidized group is atomized and then taken in through the respiratory tract, so that the water rich in the oxidized group directly acts on the respiratory tract and the lung, the effect is fast, the effect is better, the atomized particles are soft, and the atomized particles have no irritation to nasal cavities and throats.

For example, the water generator comprises an electrolysis cavity, and an anode, a proton exchange membrane and a cathode which are sequentially arranged in the electrolysis cavity, and pure water or tap water is injected into the electrolysis cavity, so that the water rich in the oxidized group is prepared and obtained in a low-pressure electrolysis manner.

Example 1

The water generator rich in the oxidizing group comprises an electrolysis cavity, wherein the electrolysis cavity is internally provided with:

anode: a conductive diamond;

cathode: titanium alloy or pure titanium;

a proton exchange membrane is arranged between the anode and the cathode.

Pure water was injected into the electrolytic chamber, and 10V DC voltage and 2A current were applied, and after 1min of operation, 3.0ppm of water rich in oxidized groups was produced.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A method for the prevention and treatment and adjuvant treatment of viral diseases of the respiratory system or pulmonary diseases, which comprises administering an effective amount of water rich in oxidized radicals to a subject.

2. The method for the prophylactic and therapeutic treatment of a viral disease of the respiratory system or a pulmonary disease as claimed in claim 1, wherein the administration is oral administration.

3. The method for prevention and treatment and adjuvant therapy of viral diseases of respiratory system or pulmonary diseases according to claim 2, wherein the water rich in oxidized radicals is used for prevention and adjuvant therapy of pulmonary diseases by absorbing oxygen in the water rich in oxidized radicals through the digestive system to supply oxygen to the subject, and oxygen is supplied to the blood circulation system through the digestive system and supplied to an aerobic site to relieve hypoxia caused by pulmonary infection in patients with pulmonary diseases.

4. The method for the prevention and treatment and adjuvant therapy of viral diseases or pulmonary diseases of the respiratory system according to claim 1, wherein said administration is via the respiratory tract after nebulization of water rich in oxidized groups.

5. The method for preventing and treating viral diseases of the respiratory system or pulmonary diseases as claimed in claim 4, wherein the water rich in oxidized radicals is used for preventing and treating pulmonary diseases by taking in water containing oxidized radicals to the respiratory tract and the lungs through the respiratory system, and killing pathogenic microorganisms in the respiratory system, including one or more of bacteria, viruses, fungi, actinomycetes, rickettsia, mycoplasma, chlamydia and spirochete, through the oxidation of the oxidized radicals in the water containing oxidized radicals.

6. The method for prevention and treatment and adjuvant therapy of viral diseases of respiratory system or pulmonary diseases according to claim 1, wherein the oxidized group in the oxidized group-rich water exists in water in a polar molecular state or an ionic state.

7. The method for the prevention and treatment and adjuvant treatment of viral diseases of the respiratory system or pulmonary diseases according to claim 1, wherein said water rich in oxidizing groups contains ozone molecules.

8. The method for prevention and treatment and adjuvant therapy of viral diseases of the respiratory system or pulmonary diseases according to claim 1, wherein said oxidized group-rich water comprises at least one of ozone, hydroxyl radical, oxygen atom and oxygen gas.

9. The method for prevention and treatment and adjuvant therapy of viral diseases of respiratory system or pulmonary diseases according to claim 7, wherein the ozone content in the oxidized group-rich water administered to the subject is 0.1 to 6 ppm.

10. The application of the water rich in the oxidized group in preventing and treating respiratory system viral diseases or lung diseases in an auxiliary way.