CN111458200A - Automatic quick slicer of biological tissue - Google Patents

Automatic quick slicer of biological tissue Download PDF

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Publication number
CN111458200A
CN111458200A CN202010289777.XA CN202010289777A CN111458200A CN 111458200 A CN111458200 A CN 111458200A CN 202010289777 A CN202010289777 A CN 202010289777A CN 111458200 A CN111458200 A CN 111458200A
Authority
CN
China
Prior art keywords
base body
vertical
driving
move
equipment base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010289777.XA
Other languages
Chinese (zh)
Inventor
何立新
曾飞熊
程淑燕
何静芳
古达洋
余平
冯誉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Anshun Da Supply Chain Management Co ltd
Original Assignee
Guangdong Anshun Da Supply Chain Management Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangdong Anshun Da Supply Chain Management Co ltd filed Critical Guangdong Anshun Da Supply Chain Management Co ltd
Priority to CN202010289777.XA priority Critical patent/CN111458200A/en
Publication of CN111458200A publication Critical patent/CN111458200A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873Cutting or cleaving

Abstract

The invention discloses an automatic quick biological tissue slicer, which comprises a base, wherein a forward slide rail and a push rod motor driving the forward slide rail to move are arranged on the base, an equipment base body is arranged on the forward slide rail, a clamping mechanism capable of clamping embedded biological tissues is arranged on the equipment base body, an up-and-down driving mechanism capable of driving the clamping mechanism to move up and down is arranged in the equipment base body, a longitudinal straight notch is arranged at the bottom of a movable blade seat, a transverse sliding block is arranged in the longitudinal straight notch to move back and forth and simultaneously drive the longitudinal straight notch to move up and down, the stroke of a clamp can be reduced, the number of cutting times of each walking is increased, and the structure is reasonable.

Description

Automatic quick slicer of biological tissue
Technical Field
The present invention relates in particular to a biological tissue microtome.
Background
In the middle of the last century, with the continuous understanding and research of diseases, besides the diagnosis of diseases from general tissues by naked eyes, the diagnosis of diseases from the change of tissue structures and cells is required, which requires the biological tissues to be made into slices of about 5um to be observed under a microscope, thus generating the biological tissue slicer, and undergoing the development stages of common biological tissue slicers and semi-automatic biological tissue slicers.
However, in the conventional cutting mode, the clamp clamps the embedded biological tissue to feed, and the clamp reciprocates up and down, when the biological tissue moves down once, the blade cuts a slice of the embedded biological tissue, and then resets and feeds the slice.
Thus, the existing biological tissue microtomes are further improved.
Disclosure of Invention
The invention aims to provide a device for quickly slicing biological tissues.
In order to achieve the purpose, the invention adopts the following scheme:
an automatic quick biological tissue slicer comprises a base, wherein an advancing slide rail and a push rod motor for driving the advancing slide rail to move are arranged on the base; the up-down driving mechanism comprises a hollow groove arranged on the equipment base body, a vertical sliding rail is arranged on the inner wall of the hollow groove, a vertical sliding block is arranged on the vertical sliding rail, a longitudinal driving block is arranged on the vertical sliding block, a straight notch is arranged in the longitudinal driving block, a transverse shaft hole is arranged in the equipment base body, a rotating shaft is rotatably arranged in the longitudinal driving block, an eccentric shaft is arranged on the rotating shaft, and the eccentric shaft is inserted into the straight notch to drive the vertical sliding block to move up and down; the equipment base body in front of the clamping mechanism is provided with a blade seat capable of moving up and down, two blades arranged in opposite directions are respectively arranged above and below the movable blade seat, the blade direction faces the clamping mechanism, the rotating shaft is provided with a synchronous eccentric shaft arranged in the opposite direction to the eccentric shaft, a vertical chute is arranged at the position of the synchronous eccentric shaft in the equipment base body, a sliding plate is vertically and movably arranged in the vertical chute, the sliding plate is provided with a transversely arranged synchronous straight chute opening, the synchronous eccentric shaft is inserted in the synchronous straight chute to be matched and driven, the end part of the sliding plate is fixedly provided with a transverse sliding block, the bottom of the movable blade seat is provided with a longitudinal straight chute opening, the transverse sliding block is arranged in the longitudinal straight chute opening to move back and forth and simultaneously drive the longitudinal straight chute opening to move up and down, and the stroke of, increase cutting number of times of walking at every turn, it is rational in infrastructure.
Furthermore, a plurality of vertical through holes are formed in the front of the clamping mechanism on the surface of the equipment seat body, vertical guide rods are movably arranged in the vertical through holes up and down, and movable blade seats are fixedly connected to the upper ends of the vertical guide rods.
Further, the vertical guide rod and the longitudinal straight notch are fixedly connected.
Preferably, the clamping mechanism comprises a synchronous vice fixedly arranged on the outer wall of the vertical sliding block, and a clamping mode is provided.
Preferably, the clamping part of the synchronous vice is in a square groove shape, so that the synchronous vice is better in adaptability.
Preferably, the outer end of the rotating shaft is provided with a stirring handle, so that the driving is convenient.
Preferably, the equipment base is provided with a driving motor, and an output shaft of the driving motor is fixedly connected with the end part of the rotating shaft, so that an electric mode is provided.
Preferably, the equipment seat body is provided with an operation panel capable of controlling the push rod motor to work.
In summary, compared with the prior art, the invention has the beneficial effects that:
the invention solves the problem that the speed of the existing biological tissue is lower in the slicing process, can reduce the stroke of the clamp, increase the cutting times of each walking and increase the working efficiency, and has simple structure and convenient use.
Drawings
FIG. 1 is a perspective view of the present invention in a motion state;
FIG. 2 is a second perspective view of the present invention in a motion state;
FIG. 3 is a front view of the present invention;
FIG. 4 is a cross-sectional view taken along line A-A of the present invention;
FIG. 5 is a cross-sectional view taken along line B-B of the present invention;
FIG. 6 is one of the exploded views of the present invention;
FIG. 7 is a second exploded view of the present invention;
fig. 8 is a schematic view of the components of the present invention.
The reference numbers illustrate: 1. a base; 2. a forward slide rail; 3. an equipment base; 4. a clamping mechanism; 5. an up-down driving mechanism; 7. a hollow groove; 8. a vertical slide rail; 9. a vertical slide block; 10. a longitudinal driving block; 11. a straight notch; 12. a rotating shaft; 13. an eccentric shaft 14, a movable blade seat; 15. a vertical through hole; 16. a vertical guide bar; 17. a knife edge; 18. a synchronous eccentric shaft; 19. a vertical chute; 20. a slide plate; 21. a synchronous straight notch; 22. a transverse slide block; 23. a longitudinal straight slot opening; 24. a synchronous vice; 25. a stirring handle; 26. and a control panel.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-8, the present invention provides a technical solution:
an automatic quick slicing machine for biological tissue comprises a base 1, wherein an advancing slide rail 2 and a push rod motor for driving the advancing slide rail 2 to move are arranged on the base 1, an equipment base body 3 is arranged on the advancing slide rail 2, a clamping mechanism 4 capable of clamping embedded biological tissue is arranged on the equipment base body 3, an up-and-down driving mechanism 5 capable of driving the clamping mechanism 4 to move up and down is arranged in the equipment base body 3, the up-and-down driving mechanism 5 comprises a hollow groove 7 arranged on the equipment base body 3, a vertical slide rail 8 is arranged on the inner wall of the hollow groove 7, a vertical slide block 9 is arranged on the vertical slide rail 8, a longitudinal driving block 10 is arranged on the vertical slide block 9, a longitudinal straight notch 11 is arranged in the longitudinal driving block 10, a transverse shaft hole is arranged in the equipment base body 3, and a rotating shaft 12 is rotatably arranged in the equipment, an eccentric shaft 13 is arranged on the rotating shaft 12, the eccentric shaft 13 is inserted in a longitudinal straight notch 11 to drive the vertical slide block 9 to move up and down, a blade seat 14 capable of moving up and down is arranged on the equipment base body 3 in front of the clamping mechanism 4, two blades 17 arranged in opposite directions are respectively arranged on the upper part and the lower part of the blade seat 14, the direction of the blade 17 faces the clamping mechanism 4, a synchronous eccentric shaft 18 arranged in the position opposite to the eccentric shaft 13 is arranged on the rotating shaft 12, a vertical sliding chute 19 is arranged at the position of the synchronous eccentric shaft 18 in the equipment base body 3, a slide plate 20 is vertically movably arranged in the vertical sliding chute 19, a synchronous straight notch 21 arranged transversely is arranged on the slide plate 20, the synchronous eccentric shaft 18 is inserted in the synchronous straight notch 21 to be matched and driven, and a transverse slide block 22 is fixedly arranged at the end part of the, the bottom of the movable blade seat 14 is provided with a longitudinal straight notch 23, the transverse sliding block 22 is arranged in the longitudinal straight notch 23 to move back and forth and simultaneously drive the longitudinal straight notch 23 to move up and down, the working principle is that the embedded biological tissue is clamped in the clamping mechanism 4, equipment is started, the advancing slide rail 2 slowly drives the biological tissue to advance to the knife edge 17 at the moment, meanwhile, the rotating shaft 12 rotates, the eccentric shaft 13 and the synchronous eccentric shaft 18 are driven to rotate in the rotating process of the rotating shaft 12, the straight notch 11 and the synchronous straight notch 21 are respectively driven to move up and down in turn in the rotating process of the eccentric shaft 13 and the synchronous eccentric shaft 18, the straight notch 11 drives the vertical sliding block 9 to move up and down, the synchronous straight notch 21 drives the blade seat 14 to move up and down, when the vertical sliding block 9 rises, the blade seat 14 descends, otherwise, through the matching of the transverse sliding block 22, the transverse sliding block 22 can move back and forth in the longitudinal straight notch 23 and can drive the vertical sliding block 9 to move up and down, so that the advancing sliding rail 2 can smoothly drive the equipment base body 3 to advance.
A plurality of vertical through holes 15 are formed in the front of a clamping mechanism 4 on the surface of an equipment seat body 3, vertical guide rods 16 are movably arranged in the vertical through holes 15 up and down, movable blade seats 14 are fixedly connected to the upper ends of the vertical guide rods 16, and the vertical guide rods 16 are fixedly connected with the longitudinal straight groove openings 23. The vertical guide bar 16 allows the movable blade holder 14 to move up and down in the vertical through hole 15.
The clamping mechanism 4 comprises a synchronous vice 24 fixedly arranged on the outer wall of the vertical sliding block 9, the clamping part of the synchronous vice 24 is in a square groove shape, and four jaws of the synchronous vice 24 synchronously move to clamp biological tissues.
One of the driving modes of the invention is as follows: the outer end of the rotating shaft 12 is provided with a stirring handle 25, and the other driving mode is as follows: and a driving motor is arranged on the equipment base body 3, and an output shaft of the driving motor is fixedly connected with the end part of the rotating shaft 12.
The equipment base body 3 is provided with an operation panel 26 which can control the work of the push rod motor, the rotation speed of the driving motor and the moving speed of the advancing slide rail 2 can be controlled through the operation panel 26, and meanwhile, the equipment can be started and closed.
While there have been shown and described the fundamental principles and principal features of the invention and advantages thereof, it will be understood by those skilled in the art that the invention is not limited by the embodiments described above, which are given by way of illustration of the principles of the invention, but is susceptible to various changes and modifications without departing from the spirit and scope of the invention as defined by the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (8)

1. An automatic quick biological tissue microtome comprises a base (1), wherein an advancing slide rail (2) and a push rod motor for driving the advancing slide rail (2) to move are arranged on the base (1), an equipment base body (3) is arranged on the advancing slide rail (2), a clamping mechanism (4) capable of clamping embedded biological tissues is arranged on the equipment base body (3), and an up-and-down driving mechanism (5) capable of driving the clamping mechanism (4) to move up and down is arranged in the equipment base body (3); the up-down driving mechanism (5) comprises a hollow groove (7) arranged on the equipment base body (3), a vertical sliding rail (8) is arranged on the inner wall of the hollow groove (7), a vertical sliding block (9) is arranged on the vertical sliding rail (8), a longitudinal driving block (10) is arranged on the vertical sliding block (9), a straight notch (11) is arranged in the longitudinal driving block (10), a transverse shaft hole is arranged in the equipment base body (3) and a rotating shaft (12) is rotatably arranged in the transverse shaft hole, an eccentric shaft (13) is arranged on the rotating shaft (12), and the eccentric shaft (13) is inserted in the longitudinal straight notch (11) to drive the vertical sliding block (9) to move up and down;
an equipment base body (3) in front of the clamping mechanism (4) is provided with a blade seat (14) capable of moving up and down, the upper part and the lower part of the movable blade seat (14) are respectively provided with two knife edges (17) arranged in opposite directions, the knife edges (17) face the clamping mechanism (4), the rotating shaft (12) is provided with a synchronous eccentric shaft (18) arranged in opposite directions to the eccentric shaft (13), a vertical sliding chute (19) is arranged in the equipment base body (3) at the position of the synchronous eccentric shaft (18), a sliding plate (20) is vertically and movably arranged in the vertical sliding chute (19), the sliding plate (20) is provided with a synchronous straight chute opening (21) transversely arranged, the synchronous eccentric shaft (18) is inserted in the synchronous straight chute opening (21) for matching driving, and the end part of the sliding plate (20) is fixedly provided with a sliding block (22) capable of, the bottom of the movable blade seat (14) is provided with a longitudinal straight notch (23), and the transverse sliding block (22) is arranged in the longitudinal straight notch (23) to move back and forth and simultaneously drive the longitudinal straight notch (23) to move up and down.
2. The automatic quick slicer of biological tissue as claimed in claim 1, wherein a plurality of vertical through holes are provided in front of the clamping mechanism (4) on the surface of the apparatus base body (3), a vertical guide rod (16) is movably provided in the vertical through holes up and down, and a movable blade seat (14) is fixedly connected to the upper end of the vertical guide rod (16).
3. An automatic rapid microtome according to claim 2, characterized in that said vertical guide bar (16) and said longitudinal notch (23) are fixedly connected.
4. An automatic rapid microtome for biological tissues as claimed in claim 3, characterized in that the clamping mechanism (4) comprises a synchronous jaw vice (24) fixedly arranged on the outer wall of the vertical slider (9).
5. An automatic rapid microtome for biological tissues as claimed in claim 4, characterized in that the clamping portion of said synchronized vise (24) is in the shape of a square groove.
6. An automatic rapid biological tissue microtome according to claim 5, wherein the outer end of said rotary shaft (12) is provided with a stirring handle (25).
7. The automatic quick slicer according to claim 6, characterized in that the device housing (3) is provided with a driving motor, and the output shaft of the driving motor is fixedly connected with the end of the rotating shaft (12).
8. The automatic quick biological tissue microtome according to claim 7, wherein the apparatus housing (3) is provided with a control panel (26) for controlling the operation of the push rod motor.
CN202010289777.XA 2020-04-14 2020-04-14 Automatic quick slicer of biological tissue Pending CN111458200A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010289777.XA CN111458200A (en) 2020-04-14 2020-04-14 Automatic quick slicer of biological tissue

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010289777.XA CN111458200A (en) 2020-04-14 2020-04-14 Automatic quick slicer of biological tissue

Publications (1)

Publication Number Publication Date
CN111458200A true CN111458200A (en) 2020-07-28

Family

ID=71684533

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010289777.XA Pending CN111458200A (en) 2020-04-14 2020-04-14 Automatic quick slicer of biological tissue

Country Status (1)

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CN (1) CN111458200A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113125226A (en) * 2021-04-16 2021-07-16 重庆医药高等专科学校 Biological tissue slicer

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JP2009066732A (en) * 2007-09-14 2009-04-02 Nantsune:Kk Meat slicer
US20090123623A1 (en) * 2005-06-09 2009-05-14 Edward Tweg Food dicer
US20130139665A1 (en) * 2011-12-02 2013-06-06 Sealed Air Corporation (Us) Slicing Apparatus
JP2013123633A (en) * 2011-12-13 2013-06-24 Masamichi Nagano Double-edged slicer
CN203041796U (en) * 2012-11-20 2013-07-10 陈正棠 Skincare fruit peeler
CN103949713A (en) * 2014-04-22 2014-07-30 河北大学 Alkaline earth metal slicing method and slicing machine special for alkaline earth metal slicing method
CN104526745A (en) * 2014-12-03 2015-04-22 重庆市川瑞俞厨食品有限公司 Slicing mechanism for bean curd
CN104833541A (en) * 2015-05-20 2015-08-12 金华市益迪医疗设备有限公司 Chuck automatic driving and reversing mechanism of manual biological tissue microtome
JP2017052091A (en) * 2015-09-10 2017-03-16 有限会社 武藤設計 Slice cutting method of long workpiece and apparatus therefor, v-groove slice cutting method of long pipe material and apparatus therefor, and portable type slice cutting machine
CN208375359U (en) * 2018-07-11 2019-01-15 晋江混元机械有限公司 A kind of automatic clinical microtome
CN209014307U (en) * 2018-11-09 2019-06-21 李嘉晨 A kind of tissue slice apparatus for Senior Biology experiment
CN209887652U (en) * 2019-04-09 2020-01-03 张掖高农生物科技服务有限公司 Blank device is used in pumpkin porridge production

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005319521A (en) * 2004-05-06 2005-11-17 Yamate Nousan:Kk Vegetable processing device
US20090123623A1 (en) * 2005-06-09 2009-05-14 Edward Tweg Food dicer
CN201069415Y (en) * 2007-06-15 2008-06-04 浙江省金华市科迪仪器有限公司 A biologic tissue slicer
JP2009066732A (en) * 2007-09-14 2009-04-02 Nantsune:Kk Meat slicer
CN103958135A (en) * 2011-12-02 2014-07-30 密封空气公司 Slicing apparatus
US20130139665A1 (en) * 2011-12-02 2013-06-06 Sealed Air Corporation (Us) Slicing Apparatus
JP2013123633A (en) * 2011-12-13 2013-06-24 Masamichi Nagano Double-edged slicer
CN203041796U (en) * 2012-11-20 2013-07-10 陈正棠 Skincare fruit peeler
CN103949713A (en) * 2014-04-22 2014-07-30 河北大学 Alkaline earth metal slicing method and slicing machine special for alkaline earth metal slicing method
CN104526745A (en) * 2014-12-03 2015-04-22 重庆市川瑞俞厨食品有限公司 Slicing mechanism for bean curd
CN104833541A (en) * 2015-05-20 2015-08-12 金华市益迪医疗设备有限公司 Chuck automatic driving and reversing mechanism of manual biological tissue microtome
JP2017052091A (en) * 2015-09-10 2017-03-16 有限会社 武藤設計 Slice cutting method of long workpiece and apparatus therefor, v-groove slice cutting method of long pipe material and apparatus therefor, and portable type slice cutting machine
CN208375359U (en) * 2018-07-11 2019-01-15 晋江混元机械有限公司 A kind of automatic clinical microtome
CN209014307U (en) * 2018-11-09 2019-06-21 李嘉晨 A kind of tissue slice apparatus for Senior Biology experiment
CN209887652U (en) * 2019-04-09 2020-01-03 张掖高农生物科技服务有限公司 Blank device is used in pumpkin porridge production

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113125226A (en) * 2021-04-16 2021-07-16 重庆医药高等专科学校 Biological tissue slicer
CN113125226B (en) * 2021-04-16 2023-09-05 重庆医药高等专科学校 Biological tissue slicer

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Application publication date: 20200728