CN111420571A - Automatic online diluting device of medicament - Google Patents

Abstract

The invention discloses an automatic online medicament diluting device, which comprises: vacuum ejector, high-efficient blender, concentration controller, first inlet tube, advance pencil and second inlet tube, its characterized in that: install the governing valve of intaking on the first inlet tube for adjust dilution water source inlet flow, be provided with the backwash filter in one side of governing valve of intaking, mutual fixed connection between backwash filter and the first inlet tube, the second inlet tube sets up in first inlet tube one side, through first connecting elbow interconnect between first inlet tube and the second inlet tube, installs a electromagnetic flowmeter on the second inlet tube. The invention can ensure the accuracy of the concentration of diluted medicines, has high speed, high efficiency, stable operation and simple and convenient operation, greatly reduces the labor cost, can effectively control the concentration deviation generated in the process of diluting the medicine, and has the advantages of simple operation, stable performance, wide application and high precision.

Description

A device for automatic online dilution of pharmaceuticals

technical field

The invention relates to the technical field of seawater desalination, in particular to an automatic online dilution device for pharmaceuticals.

Background technique

At present, as one of the necessary raw materials for the production process of chemicals widely used in the water treatment industry, chemical industry and power industry, due to the limitation of transportation costs between production and use areas, in order to facilitate transportation and storage of its original The state is generally pharmaceutical powder or concentrated solution. After temporary configuration, mixing and storage on the production site, it is added to the workshop production line through the pharmaceutical dissolution or dilution device.

In the current prior art, there are the following mainstream types of pharmaceutical dilution devices: (1) The dilution ratio is controlled by controlling the rotation speed, flow rate, or time of the chemical pump and the dilution pump, but with the prolongation of the water pump use time, the water pump , pipeline aging, failure will affect the flow of the medium pumped, thereby affecting the dilution ratio of chemicals and water samples. (2) The injection volume of water samples and pharmaceuticals is precisely controlled by the micro metering pump, but the cost of the micro injection pump is high, and the error is large when the dilution ratio is large. (3) Fully mixing and stirring according to the dilution ratio of the pharmaceutical agent through the large container has reached the dilution concentration, and is transported to the workshop production line through the pharmaceutical pump, but this method occupies a large area, the dilution rate is slow, the efficiency is low, the precision is low, and the controllable The performance is poor, and the pipeline cannot be flushed online.

The above-mentioned existing medicament dilution device also has the following shortcomings:

(1) The existing pharmaceutical dilution device has a single matching raw material, that is, only a dilution process of a specific pharmaceutical and a specific dilution water source can be used, which specifically involves poor reusability.

(2) The dilution process of the existing pharmaceutical dilution device has a small adjustable range, complex structure, high cost, low efficiency, complex operation, poor controllability, large footprint, and low degree of automation.

(3) The existing medicament dilution device is prone to the problem that the medicament on the inner wall of the conveying pipeline is hardened, resulting in poor dosing of the medicament or blockage of the pipeline.

(4) The mixing effect of the existing medicament dilution device is poor, and it is easy to cause the problem of insufficient mixing of the medicament, resulting in the concentration deviation of the medicament dosing solution.

(5) The dilution water source of the existing chemical dilution device is generally fresh water. The dilution process has a long continuous time and a large water consumption per unit time, resulting in a serious waste of fresh water resources.

Therefore, there is a need for an automatic online dilution device for medicines that can solve the above problems.

SUMMARY OF THE INVENTION

In view of the above-mentioned problems, the purpose of the present invention is to provide an automatic online dilution device for pharmaceuticals. The present invention is mainly aimed at an automatic pharmaceutical dilution device proposed for the pharmaceutical dilution process of the pretreatment unit of the seawater desalination system. The effluent replaces the original industrial water (desalinated water) and saves a lot of freshwater resource consumption. It has certain technical reference value for the pharmaceutical configuration, mixing and dilution process of the same type of seawater desalination system.

The technical solution adopted by the present invention to solve the above-mentioned technical problems is: an automatic online dilution device for pharmaceuticals, comprising: a vacuum ejector, a high-efficiency mixer, a concentration controller, a first water inlet pipe, a medicine inlet pipe and a second water inlet pipe, It is characterized in that: a water inlet regulating valve is installed on the first water inlet pipe, which is used to adjust the inlet water flow of the dilution water source, and a backwash filter is arranged on one side of the water inlet regulating valve, and the backwash filter is connected with the first water inlet. A water inlet pipe is fixedly connected to each other, the second water inlet pipe is arranged on one side of the first water inlet pipe, the first water inlet pipe and the second water inlet pipe are connected to each other through a first connecting elbow, and the second water inlet pipe is connected to each other through a first connecting elbow. A first electromagnetic flowmeter is installed on the water inlet pipe, which is used to feed back real-time flow monitoring data to an external logic control system. A first check valve is installed on the second water inlet pipe, and the first check valve is located at the first electromagnetic flow rate. The upper end of the meter, the vacuum ejector is arranged on the upper end of the medicine feeding pipe, one end of the vacuum ejector is connected to the second water inlet pipe through a second connecting elbow, and the lower end of the vacuum ejector is connected to the second water inlet pipe. The medicine feeding pipes are connected with each other, and the medicine feeding regulating valve, the second check valve and the second electromagnetic flowmeter are installed on the medicine feeding pipe. The working principle and structure of the second electromagnetic flowmeter are the same as the first electromagnetic flow rate. The high-efficiency mixer is fixedly connected to one end of the vacuum ejector, the inlet of the high-efficiency mixer and the high-efficiency mixer communicate with each other, and the concentration controller is installed at the outlet end of the high-efficiency mixer. The concentration controller is used for Monitor the concentration value of the dilution agent at the outlet of the high-efficiency mixer.

Further, the vacuum ejector is a vacuum device that uses fluid to transmit energy and mass. The dilution water source with a certain pressure inside it is sprayed out through the nozzles symmetrically and uniformly distributed to a certain side inclination, and converges on a focus. , convert the pressure energy into velocity energy, reduce the pressure in the suction area to generate negative pressure as the suction power source of the concentrated medicine, and at the same time as a preliminary mixing device for the dilution water source and the concentrated medicine.

Further, the working principle and structure of the first check valve are the same as those of the second check valve. In order to avoid the reverse flow of the fluid due to special reasons.

Further, a pressure regulating valve is installed on the first water inlet pipe, and the pressure regulating valve is an adjustable mechanical part, and is used to regulate the fluctuation caused by the flow and pressure of the dilution water source within a certain range.

Further, the backwashing filter is a continuous on-line backwashing filter, and the backwashing operation is automatically performed when the pressure difference between the two ends of the inlet and outlet is higher than the set value.

Further, the water inlet regulating valve is an electric control valve, which can freely adjust the opening degree according to the control signal of the logic system, so as to adjust the water inlet flow rate of the dilution water source.

Further, the material of the second electromagnetic flowmeter is different from that of the second electromagnetic flowmeter, and the second electromagnetic flowmeter is made of corrosion-resistant polytetrafluoroethylene plastic, which is used in the process of monitoring the flow of different types of medicines.

Further, the concentration controller is an on-line concentration monitoring device, the function of which is to monitor the concentration value of the dilution agent at the outlet of the high-efficiency mixer in real time and feed it back to the logic control system.

Further, the high-efficiency mixer is a medicament mixing device with a spiral internal flow channel and a mixed flow baffle, which is used to promote the full mixing effect of the medicament and provide a basis for the concentration monitored by the subsequent concentration controller.

The advantages of the present invention are as follows: the present invention provides an automatic online dilution device for medicaments, the present invention is a high-efficiency mixing and dilution device for reducing the concentration used in the dosing process of the medicament, and the present invention is mainly aimed at the adjustable adjustment of the existing medicament dilution device. Small scope, complex structure, high cost, low efficiency, complex operation, poor controllability, large floor space, low degree of automation and other problems, an automatic online dilution device for pharmaceuticals is proposed. It is an automatic dilution device that is suitable for liquid medicines of various concentrations and can take into account the online real-time adjustment of the dilution concentration of the medicines. Compared with the traditional pharmaceutical dilution method, the present invention has obvious advantages. This device can ensure the accuracy of the diluted pharmaceutical concentration, has high speed, high efficiency, stable operation, simple operation, greatly reduces labor costs, and can effectively control pharmaceuticals. The concentration deviation generated during the dilution process has the advantages of simple operation, stable performance, wide application and high precision.

Description of drawings

In order to illustrate the specific embodiments of the present invention or the technical solutions in the prior art more clearly, the following briefly introduces the accompanying drawings that need to be used in the description of the specific embodiments or the prior art. Obviously, the accompanying drawings in the following description The drawings are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can also be obtained based on these drawings without creative efforts.

FIG. 1 is a schematic diagram of the arrangement structure of the present invention.

FIG. 2 is a schematic diagram of the dilution water source water supply system of the present invention.

FIG. 3 is a schematic diagram of the working principle of the backwash filter in the present invention in a normal filtering state (the water flow guide valve is open).

FIG. 4 is a schematic diagram of the working principle of the backwash filter in the present invention under the condition of backwashing and sewage discharge (the water flow guide valve is closed).

in:

1. Water inlet regulating valve; 2. Backwash filter; 3. Pressure regulating valve;

4. The first electromagnetic flowmeter; 5. The first check valve; 6. The medicine feeding control valve;

7. The second electromagnetic flowmeter; 8. The second check valve; 9. The vacuum ejector;

10. High-efficiency mixer; 11. Concentration controller; 12. The first water inlet pipe;

13. Medicine inlet pipe; 14. The first connecting elbow; 15. The second water inlet pipe;

16. The second connecting elbow

Detailed ways

The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical" and "horizontal" unless otherwise expressly specified and limited The orientation or positional relationship indicated by , "inside", "outside", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the indicated device or element must be It has a specific orientation, is constructed and operates in a specific orientation, and therefore should not be construed as a limitation of the present invention. In addition, the terms "first", "second" and "third" are only used for descriptive purposes and should not be construed as indicating or implying relative importance, and the terms "installed", "connected" and "connected" should be construed broadly For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or an internal connection between two components. of connectivity. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood in specific situations.

Example 1:

1 is a schematic diagram of the layout structure of the present invention, FIG. 2 is a schematic diagram of a dilution water source water supply system of the present invention, FIG. 3 is a schematic diagram of the working principle of the backwash filter in the present invention in a normal filtering state (the water flow guide valve is open), and FIG. 4 It is a schematic diagram of the working principle of the backwash filter in the backwashing and sewage discharge state (the water flow guide valve is closed) in the present invention, as shown in Figure 1, Figure 2, Figure 3 and Figure 4. A kind of automatic online dilution device for pharmaceuticals, including: The vacuum ejector 9, the high-efficiency mixer 10, the concentration controller 11, the first water inlet pipe 12, the medicine inlet pipe 13 and the second water inlet pipe 15 are characterized in that: the first water inlet pipe 12 is installed with a water inlet regulating valve 1. It is used to adjust the influent flow of the dilution water source. A backwash filter 2 is provided on one side of the water inlet control valve 1. The backwash filter 2 and the first water inlet pipe 12 are fixedly connected to each other. The second water inlet pipe 15 is arranged on one side of the first water inlet pipe 12 , the first water inlet pipe 12 and the second water inlet pipe 15 are connected to each other through a first connecting elbow 14 , and a second water inlet pipe 15 is installed on the second water inlet pipe 15 . An electromagnetic flowmeter 4 for feeding back real-time flow monitoring data to an external logic control system, a first check valve 5 is installed on the second water inlet pipe 15, and the first check valve 5 is located in the first electromagnetic flowmeter 4 The upper end of the vacuum ejector 9 is arranged on the upper end of the medicine feeding pipe 13, and one end of the vacuum ejector 9 is connected to the second water inlet pipe 15 through the second connecting elbow 16, and the vacuum ejection The lower end of the device 9 is communicated with the medicine feed pipe 13, and the medicine feed control valve 6, the second check valve 8 and the second electromagnetic flowmeter 7 are installed on the medicine feed pipe 13. The operation of the second electromagnetic flowmeter 7 The principle and structure are the same as the first electromagnetic flowmeter 4, the high-efficiency mixer 10 is fixedly connected to one end of the vacuum ejector 9, the inlet of the high-efficiency mixer 10 and the high-efficiency mixer 10 communicate with each other, the concentration The controller 11 is installed at the outlet end of the high-efficiency mixer 10 , and the concentration controller 11 is used to monitor the concentration value of the dilution agent at the outlet of the high-efficiency mixer 10 .

In the above scheme, the water inlet regulating valve 1 is an electric control valve, which can freely adjust the opening degree according to the control signal of the logic system to adjust the inlet water flow of the dilution water source; the backwash filter 2 is a continuous online Type backwash filter, when the pressure difference between the inlet and outlet is higher than the set value, the backwash operation process will be automatically carried out (involving the filter backwash principle as shown in Figures 3 and 4 in the accompanying drawings), during which some dilution water sources still pass through This enables continuous operation.

The pressure regulating valve 3 is an adjustable mechanical part, which is used to adjust the fluctuation caused by the flow and pressure of the dilution water source within a certain range, thereby ensuring the stable flow of the flow and avoiding the fluctuation and deviation of the concentration of the dilution agent to the greatest extent;

The first electromagnetic flowmeter 4 is a real-time flow monitoring component that can feed back real-time flow monitoring data to the logic control system; the second electromagnetic flowmeter 7 works in the same way as the first electromagnetic flowmeter 4 in the structural form, except for the difference. The second electromagnetic flowmeter 7 is made of corrosion-resistant PTFE plastic, which is suitable for different types of chemical flow monitoring processes;

The first check valve 5 is a one-way fluid flow control mechanical component, and its function is to avoid the reverse flow of the fluid due to special reasons; the working principle and structural form of the second check valve 8 are the same as those of the first check valve. Valve 5 is the same;

The vacuum ejector 9 is a vacuum device that uses fluid to transmit energy and quality. The dilution water source with a certain pressure inside is sprayed out through the nozzles symmetrically and uniformly distributed to a certain side inclination, and converges on a focus. Convert the pressure energy into velocity energy, reduce the pressure in the suction area to generate negative pressure as the source of inhalation power for the concentrated medicine, and serve as a preliminary mixing device for the dilution water source and the concentrated medicine;

The high-efficiency mixer 10 is a medicament mixing device with a spiral internal flow channel and a mixed flow baffle, which is used to promote the full mixing effect of the medicament and provide a basis for the concentration monitored by the subsequent concentration controller 11; The concentration controller 11 is an online concentration monitoring device, and its function is to monitor the concentration value of the dilution agent at the outlet of the high-efficiency mixer 10 in real time and feed it back to a logic control system, which is the central control device of the automatic online dilution device, It can monitor the deviation between the real-time concentration and the command concentration according to the concentration controller 11 and the flow data of the first electromagnetic flowmeter 4 and the second electromagnetic flowmeter 7 (under the premise that the concentration of the concentrated drug is known, it can be controlled by controlling the first and second electromagnetic flowmeters. The second electromagnetic flowmeter 7 realizes the precise concentration dilution process through the flow rate), which is used to adjust the opening of the water inlet regulating valve 1 and the medicine feeding regulating valve 6 in real time, so as to realize a continuous, automatic and accurate pharmaceutical dilution process; the first, The second electromagnetic flowmeter 7, the water inlet regulating valve 1, the medicine inlet regulating valve 6, and the concentration controller 11 are respectively controllable and connected to the logic control system;

When the logic control system receives the shutdown instruction of the automatic online dilution device, it automatically executes the cleaning procedure. The specific operations are briefly summarized as follows: close the medicine inlet regulating valve 6, keep the water inlet regulating valve 1 open, and implement continuous cleaning for the subsequent pipelines of the online dilution device. , to avoid the blocking of the pipeline after the drug adheres and solidifies, and the flushing time can be freely adjusted according to the actual operation cycle of the online dilution device or the sampling concentration of the detection point.

Working mode: The present invention provides an automatic online dilution device for medicaments. The present invention uses seawater as the dilution water source (the dilution water source is specifically the seawater pretreatment high-efficiency coagulation sedimentation tank (which can remove most of the suspended solids and slime in the seawater) The effluent is transported to the pharmaceutical dilution device through a booster centrifugal pump, a filter, a pressure regulating valve 3, etc., see Figure 2 of the accompanying drawings in this specification for details) through the water inlet regulating valve 1 (according to the feedback signal of the concentration controller 11, the logic control system adjusts in real time Inlet water regulating valve 1 and medicine feeding regulating valve 6 opening state), backwash filter 2 (filtering and intercepting the impurity particles that may exist in the diluted water sample), pressure regulating valve 3 (stabilizing the inlet water pressure to avoid flow fluctuations affecting the drug) Dilution concentration), the first electromagnetic flow section (real-time monitoring of the diluted water sample flow, and feedback the data signal to the logic control system), the first check valve 5 (to avoid the dilution water sample, the backflow of the medicine) into the vacuum ejector 9, in the Due to the extremely high flow rate of the diluted water sample inside it, the pressure energy is converted into velocity energy, and the negative pressure is generated by the pressure reduction in the suction area as the power source for the inhalation of the concentrated drug; The water inlet regulating valve 1 is not set here because the filter has been set at the outlet of the concentrated medicine box), the second electromagnetic flow section (the principle of action is the same as that of the first electromagnetic flowmeter 4), and the second check valve 8 (the principle is the same as that of the first electromagnetic flowmeter 4). A check valve 5) enters the suction area of the vacuum ejector 9 and is initially mixed with the diluted water sample, and then enters the high-efficiency mixer 10 (the internal flow channel is set to a spiral type and is equipped with a mixed flow baffle to promote the mixing effect of the medicine) for Secondary mixing, the final mixed and diluted medicament is added to the dosing point after passing through the concentration controller 11. During the period, the concentration controller 11 can monitor the deviation between the actual concentration and the command concentration and the first electromagnetic flowmeter 4 and the second electromagnetic flowmeter. 7. Monitor the flow data and feed it back to the logic control system for real-time adjustment of the opening of the water inlet regulating valve 1 and the medicine inlet regulating valve 6, so that a continuous, automatic and accurate pharmaceutical dilution process can be realized.

Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, but not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: The technical solutions described in the foregoing embodiments can still be modified, or some or all of the technical features thereof can be equivalently replaced; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the embodiments of the present invention. scope.

Claims (9)

1. a medicament automatic online dilution device, comprising: vacuum ejector, high-efficiency mixer, concentration controller, the first water inlet pipe, the medicine inlet pipe and the second water inlet pipe, it is characterized in that: the first water inlet pipe is installed on the There is a water inlet regulating valve, which is used to adjust the inlet water flow of the dilution water source. A backwash filter is arranged on one side of the water inlet regulating valve. The backwash filter and the first water inlet pipe are fixedly connected to each other. The second water inlet pipe is arranged on one side of the first water inlet pipe, the first water inlet pipe and the second water inlet pipe are connected to each other through a first connecting elbow, and a first electromagnetic flowmeter is installed on the second water inlet pipe. In order to feed back the real-time flow monitoring data to the external logic control system, a first check valve is installed on the second water inlet pipe, the first check valve is located at the upper end of the first electromagnetic flowmeter, and the vacuum ejector is arranged at the The upper end of the medicine feeding pipe, one end of the vacuum ejector is connected with the second water inlet pipe through the second connecting elbow, the lower end of the vacuum ejector and the medicine feeding pipe are connected with each other, and the medicine feeding pipe is connected to each other. A medicine feeding regulating valve, a second check valve and a second electromagnetic flowmeter are installed on it. The working principle and structure of the second electromagnetic flowmeter are the same as those of the first electromagnetic flowmeter. The high-efficiency mixer is fixedly connected to the vacuum At one end of the injector, the inlet of the high-efficiency mixer communicates with the high-efficiency mixer. The concentration controller is installed at the outlet of the high-efficiency mixer, and the concentration controller is used to monitor the concentration value of the dilution agent at the outlet of the high-efficiency mixer. 2. The automatic online dilution device of a medicament according to claim 1, wherein the vacuum ejector is a vacuum device that utilizes fluid to transmit energy and quality, and a dilution water source with a certain pressure in it passes through Symmetrically distributed nozzles with a certain side inclination spray out, converge on a focus, convert pressure energy into velocity energy, reduce the pressure in the suction area and generate negative pressure as the source of suction power for concentrated pharmaceuticals, as well as the source of dilution water and Preliminary mixing device for concentrated pharmaceuticals. 3. The device for automatic online dilution of medicaments according to claim 1, wherein the working principle and structure of the first check valve are the same as those of the second check valve, and the first check valve is the same as the second check valve. Both the second check valve and the one-way flow control mechanical part of the fluid, which are used to avoid the reverse flow of the fluid due to special reasons. 4. The device for automatic online dilution of medicaments according to claim 1, characterized in that: a pressure regulating valve is installed on the first water inlet pipe, and the pressure regulating valve is an adjustable mechanical part, which is used for a certain range of Internal regulation of fluctuations caused by dilution water flow and pressure. 5. The automatic online dilution device for medicament according to claim 1, wherein the backwash filter is a continuous online backwash filter, and when the pressure difference between the inlet and outlet ends is higher than the set value After the value is set, the backwash operation is performed automatically. 6. The device for automatic online dilution of medicaments according to claim 1, wherein the water inlet regulating valve is an electric control valve, which can freely adjust the opening degree according to the control signal of the logic system, and is used to adjust the inlet of the dilution water source. water flow. 7 . The device for automatic online dilution of medicaments according to claim 1 , wherein the material of the second electromagnetic flowmeter is different from that of the second electromagnetic flowmeter, and the second electromagnetic flowmeter is made of corrosion-resistant polytetrafluoroethylene. 8 . Vinyl fluoride plastic, used in different types of chemical flow monitoring process. 8. The device for automatic online dilution of a medicament according to claim 1, wherein the concentration controller is an online concentration monitoring device, and its function is to monitor the feedback of the concentration value of the diluted medicament at the outlet of the high-efficiency mixer in real time. to the logic control system. 9 . The automatic online dilution device for medicament according to claim 1 , wherein the high-efficiency mixer is a medicament mixing device with a helical internal flow channel and a mixed flow baffle. 9 . This promotes the full mixing effect of the agent and provides a basis for the concentration monitored by the subsequent concentration controller.

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