CN111419487A - Adjustable self-stress stimulation artificial vertebral body - Google Patents
Adjustable self-stress stimulation artificial vertebral body Download PDFInfo
- Publication number
- CN111419487A CN111419487A CN202010367859.1A CN202010367859A CN111419487A CN 111419487 A CN111419487 A CN 111419487A CN 202010367859 A CN202010367859 A CN 202010367859A CN 111419487 A CN111419487 A CN 111419487A
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- outer sleeve
- inner sleeve
- sleeve
- stress
- vertebral body
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- 230000000638 stimulation Effects 0.000 title claims abstract description 10
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 42
- 230000007246 mechanism Effects 0.000 claims description 8
- 230000005489 elastic deformation Effects 0.000 claims description 7
- 239000000956 alloy Substances 0.000 claims description 3
- 229910045601 alloy Inorganic materials 0.000 claims description 3
- 239000011247 coating layer Substances 0.000 claims description 3
- 230000004936 stimulating effect Effects 0.000 claims 8
- 230000004938 stress stimulation Effects 0.000 abstract description 7
- 230000012010 growth Effects 0.000 abstract description 5
- 230000004927 fusion Effects 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 208000010392 Bone Fractures Diseases 0.000 description 3
- 206010017076 Fracture Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000008468 bone growth Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 208000006386 Bone Resorption Diseases 0.000 description 1
- 208000020084 Bone disease Diseases 0.000 description 1
- 206010065687 Bone loss Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 206010061363 Skeletal injury Diseases 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000010072 bone remodeling Effects 0.000 description 1
- 230000024279 bone resorption Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000963 osteoblast Anatomy 0.000 description 1
- 210000002997 osteoclast Anatomy 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 230000036578 sleeping time Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30074—Properties of materials and coating materials stretchable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30721—Accessories
- A61F2/30734—Modular inserts, sleeves or augments, e.g. placed on proximal part of stem for fixation purposes or wedges for bridging a bone defect
- A61F2002/30738—Sleeves
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses an adjustable self-stress stimulation artificial vertebral body, which comprises an outer sleeve, an inner sleeve and a deformable structure, wherein the outer sleeve is fixedly connected with the outer sleeve; the outer sleeve and the inner sleeve are both provided with an opening at one end, the other end of the outer sleeve is provided with an end face, the opening end of the outer sleeve is sleeved at the opening end of the inner sleeve, the outer sleeve and the inner sleeve are in sliding fit, and the outer sleeve and the inner sleeve are supported by an adjustable elastic supporting structure; the deformable structure is positioned in the outer sleeve and the inner sleeve and supports the end surfaces of the outer sleeve and the inner sleeve, and the deformable structure comprises axial deformation along the outer sleeve and the inner sleeve; the side wall of the outer sleeve and/or the inner sleeve is provided with a bone grafting hole. The invention can provide axial stress and radial stress, is beneficial to the growth and fusion of bones, and can also provide stress stimulation when a patient lies horizontally.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to an adjustable self-stress stimulation artificial vertebral body.
Background
The adjustable self-stress at the present stage stimulates the artificial vertebral body, has the function of distraction, but has complex operation when in distraction; failure to produce stable, appropriate elastic deformation and stress stimuli; in particular, the stress magnitude cannot be precisely adjusted and the problem of lack of stress stimulation in the horizontal position cannot be solved.
The stress stimulation, the growth and development of human bone tissues and the rehabilitation process of bone diseases are continuously modeled and rebuilt to adapt to the surrounding environment. The bone structure can be continuously reconstructed and shaped to adapt to the change of external environment only in the mechanical environment which is continuously adapted to bear stress stimulation generated by external force.
Stress adaptability of bones is also called functional adaptability of bones, and is characterized in that when bone needs to be increased, bone formation increases the capacity of the bones to complete the functions; when reduction is desired, there is bone resorption, reducing their ability to perform their function, and it is seen that changes in bone growth, development, atrophy and regression are closely related to the stresses to which they are subjected. The process of bone remodeling is the continuous growth, strengthening and resorption of living bone. The goal of bone reconstruction is always to adapt the internal structure and external morphology to changes in their loading environment, which can be divided into two categories: surface reconstruction and internal reconstruction. Resurfacing, which refers to the resorption or deposition of bone material on the bone surface, is a long slow process that typically lasts for months or years; the internal reconstruction refers to the change of the volume density and the quality of the bone tissue caused by the change of the mineral content and the porosity in the bone tissue, and can be completed in a short time. In humans, bone injury is remodeled in a short period of time, on the order of several weeks.
One study in russia and the united states showed that flying in space for more than 10 months resulted in total bone loss, with a 12% and 8.2% decrease in pelvis and femur, respectively, but the skull had no significant decrease in bone mass due to increased flow to the head as blood was redistributed under weightless conditions and blood flow stress was stimulated to compensate for head bone mass.
Stress shielding effect in bone biomechanics, and stress shielding phenomenon is important embodiment of bone reconstruction effect. In bone, osteoblasts and osteoclasts in bone tissue regulate the growth or resorption of bone by sensing mechanical stimuli. When the strain of the bone is lower than 50-100 micro strain and the stress is lower than 1-2MPa, the bone tissue absorbs; when the strain of the bone is higher than 1000-1500 micro strain and the stress is higher than about 20MPa, the bone tissue grows; when the strain of the bone is further higher than about 3000 microstrain and the stress is higher than about 60MPa, the bone tissue is damaged.
When stress shielding occurs in bone tissues, the stress level on bones is often in a low level for a long time, so that the bone tissues are gradually absorbed, osteoporosis of fracture parts is caused, and the bone tissues become an important cause of postoperative re-fracture.
Wolff's law: the function of the skeleton, which is to withstand the mechanical strain of the bone tissue during activity, has been recognized a century ago as the phenomenon known as Wolff's law (wulff's law). Bone forces aim to achieve an optimal structure, i.e. the morphology and material of the bone is regulated by the activity level of the individual, so that it is sufficient to bear the mechanical load, but not to increase the burden of metabolic transport.
Bones are living organisms and have their own laws of change. Wolff's law states that: bone growth is affected by mechanical stimuli to change its structure. The use is strong, and the waste is weak.
At present, various elastic deformation technologies utilize elastic materials and mechanical design, and utilize self gravity, deformation can be generated under the conditions of standing and loading and during standing activities, so that compression micro deformation can be generated, and the fractured ends or the bone grafting parts of vertebrae can bear more stress stimulation, thereby achieving the effects of stress promotion of bone formation, fracture healing and intervertebral fusion. The patient can not generate compression micro-deformation when lying down or lying in bed for sleeping, the average sleeping time of the adult can be about 8 hours, the postoperative patient can not bear load for a long time and has pain, the patient lying time can reach 15 hours or more, the bone grafting fusion and the rapid rehabilitation of the patient are not facilitated, and therefore the patient lying in bed for a long time after the operation is lack of stress stimulation to improve the design of the implant.
Disclosure of Invention
The invention aims to provide an adjustable self-stress stimulation artificial vertebral body which can provide axial stress and radial stress, is beneficial to the growth and fusion of bones and can also provide stress stimulation when a patient lies horizontally.
In order to achieve the purpose, the invention is realized by adopting the following technical scheme:
the invention discloses an adjustable self-stress stimulation artificial vertebral body, which comprises an outer sleeve, an inner sleeve and a deformable structure, wherein the outer sleeve is fixedly connected with the outer sleeve; the outer sleeve and the inner sleeve are both provided with an opening at one end, the other end of the outer sleeve is provided with an end face, the opening end of the outer sleeve is sleeved at the opening end of the inner sleeve, the outer sleeve and the inner sleeve are in sliding fit, and the outer sleeve and the inner sleeve are supported by an adjustable elastic supporting structure; the deformable structure is positioned in the outer sleeve and the inner sleeve and supports the end surfaces of the outer sleeve and the inner sleeve, and the deformable structure comprises axial deformation along the outer sleeve and the inner sleeve; the side wall of the outer sleeve and/or the inner sleeve is provided with a bone grafting hole.
Furthermore, the side wall of the outer sleeve and/or the inner sleeve is provided with a plurality of through holes, the through holes are communicated with the inner cavity of the outer sleeve and/or the inner sleeve, and the plurality of through holes are arranged on the periphery of the outer sleeve and/or the inner sleeve.
Furthermore, the end surfaces of the outer sleeve and the inner sleeve are provided with non-locking nails, the non-locking nails are used for fixing the outer sleeve and the inner sleeve, and the non-locking nails are provided with micro-motion devices.
Preferably, the end surfaces of the outer sleeve and the inner sleeve are elastic alloy or the end surfaces of the outer sleeve and the inner sleeve are provided with a coating layer or the end surfaces of the outer sleeve and the inner sleeve are in a porous structure.
Furthermore, gaskets are arranged on the end surfaces of the outer sleeve and the inner sleeve.
Preferably, the adjustable elastic support structure comprises an expansion body and a screw, the expansion body is provided with an axial hole, the diameter of the screw is larger than that of the axial hole, the expansion body is positioned in a gap between the outer sleeve and the inner sleeve, and the expansion body is attached to the side wall of the outer sleeve or the inner sleeve.
As another preference, the adjustable resilient support structure comprises a lead screw thread adjustment mechanism.
Preferably, the deformable structure is an elastically deformable structure.
Preferably, the elastic deformation mechanism comprises a threaded spring, two ends of the threaded spring are respectively connected with elastic pieces, and the two elastic pieces respectively support the inner end surfaces of the outer sleeve and the inner sleeve.
The invention has the following beneficial effects:
1. the adjustable elastic supporting structure can adjust the axial stress of the adjustable self-stress stimulation artificial vertebral body, so that the stress is in an ideal range.
2. The deformable structure can provide radial stress for the adjustable self-stress stimulation artificial vertebral body, so that axial stress can be generated in the horizontal position after adjustment. When standing upright, the stress is aggravated by the self-gravity, and the stress transmitted by the bone rises.
3. The adjustable resilient support structure enables the invention to be matched to different sizes.
Drawings
Fig. 1 is a cross-sectional view of the present invention.
Fig. 2 is a front view of the present invention.
FIG. 3 is an enlarged partial view of a portion of the adjustable resilient support structure.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the accompanying drawings.
As shown in fig. 1 and 2, the adjustable self-stress stimulation artificial vertebral body disclosed by the invention comprises an outer sleeve 2, an inner sleeve 1 and a deformable structure; the outer sleeve 2 and the inner sleeve 1 are both provided with an opening at one end, the other end is provided with an end face, the opening end of the outer sleeve 2 is sleeved at the opening end of the inner sleeve 1, the outer sleeve 2 and the inner sleeve 1 are in sliding fit, and the outer sleeve 2 and the inner sleeve 1 are supported through an adjustable elastic supporting structure 3; the deformable structure is positioned in the outer sleeve 2 and the inner sleeve 1, supports the end surfaces of the outer sleeve 2 and the inner sleeve 1 and comprises axial deformation along the outer sleeve 2 and the inner sleeve 1; the side wall of the outer sleeve 2 and/or the inner sleeve 1 is provided with bone grafting holes 6. The side wall of the outer sleeve 2 and/or the inner sleeve 1 is provided with a through hole 8, the through hole 8 is communicated with the inner cavity of the outer sleeve 2 and/or the inner sleeve 1, and a plurality of through holes 8 are arranged on the periphery of the outer sleeve 2 and/or the inner sleeve 1.
The end surfaces of the outer sleeve 2 and the inner sleeve 1 are elastic alloy or the end surfaces of the outer sleeve 2 and the inner sleeve 1 are provided with a coating layer 7 or the end surfaces of the outer sleeve 2 and the inner sleeve 1 are in a porous structure.
The end surfaces of the outer sleeve 2 and the inner sleeve 1 are provided with non-locking nails which are used for fixing the outer sleeve and the inner sleeve, and the non-locking nails are provided with micro-motion devices. The non-locking pin and the micro-motion device are conventional in the art and are not shown.
The deformation structure can adopt an elastic deformation mechanism, the elastic deformation mechanism comprises a threaded spring 5, two ends of the threaded spring 5 are respectively connected with elastic pieces 4, and the two elastic pieces 4 respectively support the inner end faces of the outer sleeve 2 and the inner sleeve 1.
As shown in fig. 3, the adjustable elastic support structure 3 comprises an expansion body 9 and a screw 11, the expansion body 9 is provided with an axial hole 10, the diameter of the screw 11 is larger than that of the axial hole 10, the expansion body 9 is positioned in the gap between the outer sleeve 2 and the inner sleeve 1, and the expansion body 9 is attached to the side wall of the outer sleeve 2 or the inner sleeve 1; when in use, the screw 11 is inserted into the axial hole 10, and the expansion body 9 is expanded by adjusting the screwing length of the screw 11.
The adjustable elastic supporting structure 3 can also adopt a screw rod thread adjusting mechanism such as a jack structure.
The present invention is capable of other embodiments, and various changes and modifications may be made by one skilled in the art without departing from the spirit and scope of the invention.
Claims (9)
1. An adjustable self-stress stimulation artificial vertebral body is characterized in that: comprising an outer sleeve, an inner sleeve and a deformable structure; the outer sleeve and the inner sleeve are both provided with an opening at one end, the other end of the outer sleeve is provided with an end face, the opening end of the outer sleeve is sleeved at the opening end of the inner sleeve, the outer sleeve and the inner sleeve are in sliding fit, and the outer sleeve and the inner sleeve are supported by an adjustable elastic supporting structure; the deformable structure is positioned in the outer sleeve and the inner sleeve and supports the end surfaces of the outer sleeve and the inner sleeve, and the deformable structure comprises axial deformation along the outer sleeve and the inner sleeve; the side wall of the outer sleeve and/or the inner sleeve is provided with a bone grafting hole.
2. The adjustable self-stress stimulating artificial vertebral body of claim 1, wherein: the side wall of the outer sleeve and/or the inner sleeve is provided with a plurality of through holes, the through holes are communicated with the inner cavity of the outer sleeve and/or the inner sleeve, and the plurality of through holes are arranged on the periphery of the outer sleeve and/or the inner sleeve.
3. The adjustable self-stress stimulating artificial vertebral body of claim 1, wherein: the end surfaces of the outer sleeve and the inner sleeve are provided with non-locking nails, the non-locking nails are used for fixing the outer sleeve and the inner sleeve, and the non-locking nails are provided with micro-motion devices.
4. The adjustable self-stress stimulating artificial vertebral body of claim 1, wherein: the end surfaces of the outer sleeve and the inner sleeve are elastic alloy or the end surfaces of the outer sleeve and the inner sleeve are provided with coating layers or the end surfaces of the outer sleeve and the inner sleeve are in porous structures.
5. The adjustable self-stress stimulating artificial vertebral body of claim 4, wherein: and gaskets are arranged on the end surfaces of the outer sleeve and the inner sleeve.
6. The adjustable self-stress stimulating artificial vertebral body of any of claims 1-5, wherein: the adjustable elastic supporting structure comprises an expansion body and a screw, wherein the expansion body is provided with an axial hole, the diameter of the screw is larger than that of the axial hole, the expansion body is positioned in a gap between the outer sleeve and the inner sleeve, and the expansion body is attached to the side wall of the outer sleeve or the inner sleeve.
7. The adjustable self-stress stimulating artificial vertebral body of any of claims 1-5, wherein: the adjustable elastic support structure comprises a screw thread adjusting mechanism.
8. The adjustable self-stress stimulating artificial vertebral body of any of claims 1-5, wherein: the deformable structure is an elastic deformation mechanism.
9. The adjustable self-stress stimulating artificial vertebral body of claim 8, wherein: the elastic deformation mechanism comprises a threaded spring, two ends of the threaded spring are respectively connected with elastic pieces, and the two elastic pieces respectively support the inner end faces of the outer sleeve and the inner sleeve.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202010367859.1A CN111419487A (en) | 2020-04-30 | 2020-04-30 | Adjustable self-stress stimulation artificial vertebral body |
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CN202010367859.1A CN111419487A (en) | 2020-04-30 | 2020-04-30 | Adjustable self-stress stimulation artificial vertebral body |
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CN111419487A true CN111419487A (en) | 2020-07-17 |
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CN202010367859.1A Pending CN111419487A (en) | 2020-04-30 | 2020-04-30 | Adjustable self-stress stimulation artificial vertebral body |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6193755B1 (en) * | 1996-09-26 | 2001-02-27 | Howmedica Gmbh | Spinal cage assembly |
US20090005787A1 (en) * | 2007-06-28 | 2009-01-01 | Angela Crall | Device and system for implanting polyaxial bone fasteners |
US20140046387A1 (en) * | 2011-03-02 | 2014-02-13 | Hipp Medical Ag | Clamping element for setting a bone fracture and fixation device comprising same |
CN205947845U (en) * | 2016-06-30 | 2017-02-15 | 常州好利医疗科技有限公司 | Bionical adjusting device of developments |
WO2017075079A1 (en) * | 2015-10-26 | 2017-05-04 | Atlas Spine, Inc. | Intervertebral expandable spacer |
CN106890037A (en) * | 2017-04-10 | 2017-06-27 | 北京大学人民医院 | One kind can extend artificial vertebral body in vivo |
CN108245289A (en) * | 2018-01-05 | 2018-07-06 | 广州中国科学院工业技术研究院 | A kind of implantable interverbebral disc |
CN212522095U (en) * | 2020-04-30 | 2021-02-12 | 四川大学华西医院 | Adjustable self-stress stimulation artificial vertebral body |
-
2020
- 2020-04-30 CN CN202010367859.1A patent/CN111419487A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6193755B1 (en) * | 1996-09-26 | 2001-02-27 | Howmedica Gmbh | Spinal cage assembly |
US20090005787A1 (en) * | 2007-06-28 | 2009-01-01 | Angela Crall | Device and system for implanting polyaxial bone fasteners |
US20140046387A1 (en) * | 2011-03-02 | 2014-02-13 | Hipp Medical Ag | Clamping element for setting a bone fracture and fixation device comprising same |
WO2017075079A1 (en) * | 2015-10-26 | 2017-05-04 | Atlas Spine, Inc. | Intervertebral expandable spacer |
CN205947845U (en) * | 2016-06-30 | 2017-02-15 | 常州好利医疗科技有限公司 | Bionical adjusting device of developments |
CN106890037A (en) * | 2017-04-10 | 2017-06-27 | 北京大学人民医院 | One kind can extend artificial vertebral body in vivo |
CN108245289A (en) * | 2018-01-05 | 2018-07-06 | 广州中国科学院工业技术研究院 | A kind of implantable interverbebral disc |
CN212522095U (en) * | 2020-04-30 | 2021-02-12 | 四川大学华西医院 | Adjustable self-stress stimulation artificial vertebral body |
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