CN111407237A - Optical ultrasonic breast cancer detector and medical equipment - Google Patents

Optical ultrasonic breast cancer detector and medical equipment Download PDF

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Publication number
CN111407237A
CN111407237A CN202010342848.8A CN202010342848A CN111407237A CN 111407237 A CN111407237 A CN 111407237A CN 202010342848 A CN202010342848 A CN 202010342848A CN 111407237 A CN111407237 A CN 111407237A
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China
Prior art keywords
ultrasonic
optical
breast cancer
dynamic scattering
cup
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CN202010342848.8A
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Chinese (zh)
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孙红岩
张国旺
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Zhejiang Dolby Medical Technology Co ltd
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Zhejiang Dolby Medical Technology Co ltd
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Priority to CN202010342848.8A priority Critical patent/CN111407237A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/0035Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0825Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the breast, e.g. mammography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4416Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

The invention discloses an optical ultrasonic breast cancer detector and medical equipment, and relates to the technical field of medical equipment. The invention fuses the dynamic scattering optical image obtained by the dynamic scattering optical imaging system and the morphological structure image obtained by ultrasonic detection, thereby improving the accuracy and efficiency of diagnosis.

Description

Optical ultrasonic breast cancer detector and medical equipment
[ technical field ] A method for producing a semiconductor device
The invention relates to the technical field of medical equipment, in particular to an optical ultrasonic breast cancer detector and medical equipment.
[ background of the invention ]
The dynamic scattering optical imaging (dynamic differential optical tomography) system is very beneficial to early diagnosis of the breast cancer, and has the advantages of low price, safety, high accuracy, no radiation and low risk compared with molybdenum target X-ray, CT, MRI and other imaging diagnosis methods. However, the existing dynamic scattering optical imaging system can only provide optical absorption information of whether tissues in the breast are cancerated, and cannot further provide position and size information of the tumor.
Ultrasonic detection is used in many applications such as medical diagnosis, treatment, and ultrasonic inspection. As an example of the medical apparatus, an ultrasound imaging apparatus emits an ultrasound signal from a surface of a subject body toward a target site of the subject, and acquires a tomographic image of soft tissue or an image of blood flow using information of the reflected (or transmitted) ultrasound signal (ultrasound echo signal) without being invasive. Compared to other image diagnostic apparatuses such as an X-ray diagnostic apparatus, an X-ray Computed Tomography (CT), a Magnetic Resonance (MRI) apparatus, and a nuclear medicine diagnostic apparatus, an ultrasonic imaging system is small in size, low in price, allows images to be displayed in real time, has no radiation exposure, has high safety, and is widely used for diagnosis of heart or abdominal regions, urinary systems, and obstetric/gynecological diseases.
In clinical diagnosis, images of a single modality often cannot provide enough information required by a doctor, so that the accuracy of diagnosis is affected, while images of different modalities require that a patient rotates multiple places to perform detection respectively, and then the doctor performs diagnosis according to a detection result, so that the diagnosis efficiency is low.
[ summary of the invention ]
In order to solve the problems, the invention provides an optical ultrasonic breast cancer detector, which fuses a dynamic scattering optical image obtained by a dynamic scattering optical imaging system and a morphological structure image obtained by ultrasonic detection, and improves the accuracy and efficiency of diagnosis.
In order to achieve the purpose, the invention adopts the following technical scheme:
an optical ultrasonic breast cancer detector comprises a cup portion, a dynamic scattering optical module and an ultrasonic piezoelectric detection module, wherein the dynamic scattering optical module is used for collecting dynamic scattering optical signals, the ultrasonic piezoelectric detection module is used for collecting ultrasonic signals, the dynamic scattering optical module comprises a CCD camera, the ultrasonic piezoelectric detection module comprises an ultrasonic probe, and the ultrasonic probe and the CCD camera are located on the inner side of the cup portion.
Optionally, the dynamic scattering optical module further includes a pressurizing balloon for pressurizing the organ to be detected, the pressurizing balloon is located between an inner side wall of the cup portion and the organ to be detected, an area covering the inner side wall of the cup portion is smaller than an area of the inner side wall of the cup portion, and a maximum distance of the pressurizing balloon in a height direction of the cup portion is smaller than a height of the cup portion.
Optionally, the dynamic scattering optics module further comprises L ED light sources for providing light to the dynamic scattering optics module, wherein the L ED light sources are distributed on the inner side wall of the cup portion between the pressurized bladder and the inner side wall of the cup portion.
Optionally, the dynamic scattering optical module further includes a laser light source for providing light to the dynamic scattering optical module, and the laser light source is disposed on the inner side wall of the cup portion and between the pressurization airbag and the inner side wall of the cup portion.
Optionally, the CCD camera is a pinhole camera, the dynamic scattering optical module includes a slide rail disposed inside the cup portion, and the CCD camera moves on the slide rail.
Optionally, the ultrasonic probe is distributed on an inner side wall of the cup portion, which is not covered by the pressurizing air bag, from the detected organ to the inner side wall of the cup portion, and the ultrasonic probe sequentially comprises an acoustic lens layer, a matching layer, a piezoelectric sensor array layer and a backing material layer.
Optionally, the ultrasonic probe further comprises a support frame for mounting it on the inside wall of the cup portion, the backing material layer being mounted on the support frame.
Optionally, the ultrasonic piezoelectric detection module further comprises a couplant bag and a couplant conduit, wherein the couplant bag is located outside the cup portion, and the couplant in the couplant bag enters the cup portion through the couplant conduit.
According to the technical scheme provided by the invention, the dynamic scattering optical imaging mode and the ultrasonic mode are fused. The ultrasonic piezoelectric detection module can perform autonomous tomography scanning in a standing state of a patient to form an accurate three-dimensional image, can obtain a dynamic scattering optical image while providing the three-dimensional image of an ultrasonic morphological structure to obtain tumor metabolic function information, realizes simultaneous and comprehensive expression of information from various imaging sources on one image, improves the diagnosis accuracy, facilitates doctors to know the comprehensive condition of pathological tissues or organs, makes more accurate diagnosis or works out more scientifically optimized treatment schemes, and simultaneously does not need the patient to carry out detection in multiple places, thereby reducing the burden of the patient and improving the diagnosis efficiency.
In addition, the invention also provides medical equipment which comprises the optical ultrasonic breast cancer detector.
Optionally, the dynamic scattering optical module and the ultrasonic piezoelectric detection module transmit signals to the medical device, and the medical device performs imaging according to the signals.
The beneficial effects of the medical equipment provided by the invention are similar to the beneficial effect reasoning process of the optical ultrasonic breast cancer detector, and are not repeated herein.
These features and advantages of the present invention will be disclosed in more detail in the following detailed description and the accompanying drawings. The best mode or means of the present invention will be described in detail with reference to the accompanying drawings, but the present invention is not limited thereto. In addition, the features, elements and components appearing in each of the following and in the drawings are plural and different symbols or numerals are labeled for convenience of representation, but all represent components of the same or similar construction or function.
[ description of the drawings ]
The invention will be further described with reference to the accompanying drawings in which:
FIG. 1 is a general schematic diagram of a first embodiment of the present invention;
FIG. 2 is a schematic structural diagram according to a first embodiment of the present invention;
FIG. 3 is a schematic diagram of an arrangement of ultrasonic probes according to a first embodiment of the present invention;
FIG. 4 is a schematic diagram of an ultrasound probe according to an embodiment of the present invention;
FIG. 5 is a schematic view of a second embodiment of the present invention;
fig. 6 is a schematic operation diagram of a second embodiment of the present invention.
[ detailed description ] embodiments
The technical solutions of the embodiments of the present invention are explained and illustrated below with reference to the drawings of the embodiments of the present invention, but the following embodiments are only preferred embodiments of the present invention, and not all embodiments. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative effort belong to the protection scope of the present invention.
Reference in the specification to "one embodiment" or "an example" means that a particular feature, structure or characteristic described in connection with the embodiment itself may be included in at least one embodiment of the patent disclosure. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment.
The first embodiment is as follows:
as shown in fig. 1, the present embodiment provides an optical ultrasonic breast cancer detector, which is used for detecting breast cancer, the overall shape of the detector is similar to that of a female bra, and a patient needs to wear the detector on his body during detection, and the detector includes a cup portion 1, a dynamic scattering optical module for collecting dynamic scattering optical signals, and an ultrasonic piezoelectric detection module for collecting ultrasonic signals, wherein the cup portion 1 is used for providing necessary space required by the worn breast, and also provides space for the dynamic scattering optical module and the ultrasonic piezoelectric detection module.
The internal structure of the cup portion 1 is shown in fig. 2, the dynamic scattering optics module includes a slide rail 2, a CCD camera 3, a compression balloon 4 and L ED light source 5, the CCD camera 3 can be a pinhole camera or other small-sized micro-camera, but not limited thereto, the CCD camera 3 moves on the slide rail 2, the slide rail 2 and the CCD camera 3 are both disposed inside the cup portion 1, the compression balloon 4 is used to compress the detected organ, i.e. the breast, between the inner side wall of the cup portion 1 and the detected organ, the area of the inner side wall of the cup portion 1 covered by the compression balloon 4 is smaller than the area of the inner side wall of the cup portion 1, at the same time, the maximum distance of the compression balloon 4 in the height direction of the cup portion 1 is smaller than the height of the cup portion 1, in other words, the compression balloon 4 covers only a portion inside the cup portion 1, after the patient wears the optical ultrasound breast cancer detector, the compression balloon 4 only applies pressure to the front half of the breast, and the root of the breast is not applied with no pressure, L ED light source L is used in other embodiments, the laser light source L is not limited to the inner side wall of the cup portion 1, and the cup portion 1.
As shown in fig. 2, the ultrasonic piezoelectric detection module includes ultrasonic probes 6, and the ultrasonic probes 6 are distributed on the inner side wall of the cup portion 1 which is not covered by the pressurized air bag 4 and are circumferentially and uniformly distributed on the inner side wall which is not covered. In other words, after the patient wears the optical ultrasound breast cancer detector, the plurality of ultrasound probes 6 ultrasonically detect the vicinity of the breast around the root thereof. Furthermore, in the present embodiment, the ultrasonic piezoelectric detection module further includes a couplant bag 7 and a couplant conduit 8, which are located outside the cup portion 1, and the couplant in the couplant bag 7 enters the cup portion 1 through the couplant conduit 8.
As shown in fig. 4, the ultrasonic probe 6 includes an acoustic lens layer 61, a matching layer 62, a piezoelectric sensor array layer 63, and a backing material layer 64. The acoustic lens layer 61 is an end directly contacting the organ to be detected for focusing in the lateral and/or longitudinal directions. The matching layer 62 serves to reduce multiple reflections due to the difference in acoustic impedance between the skin and the acoustic lens layer 61. The piezoelectric sensor array element layer 63 includes a piezoelectric material, which may be a piezoelectric crystal or a composite piezoelectric material, and the geometric shape and size thereof may be designed according to the diagnostic scenario and requirements, including various shape designs such as a convex array, a linear array, etc., which are not limited herein. The piezoelectric sensor array element layer 63 is used for transmitting/receiving ultrasonic waves to complete the sound electricity and electricity-sound conversion work, and can convert an electric signal into an ultrasonic signal and convert the ultrasonic signal into an electric signal, namely, the piezoelectric sensor array element layer has double functions of ultrasonic transmission and ultrasonic receiving. Under the power-on state, the piezoelectric material can generate elastic deformation, so that ultrasonic waves are generated; in the opposite case, when the ultrasonic wave passes through the piezoelectric material, it can generate elastic deformation, and then the voltage is changed. The backing material layer 64 serves to dampen vibrations from the piezoelectric material, shorten the wavelength and improve axial resolution. The ultrasonic piezoelectric detection module generates required images by controlling ultrasonic signals transmitted by the ultrasonic piezoelectric detection module or utilizing received ultrasonic signals, and allows images to be displayed in real time without radiation exposure, thereby having high safety. The ultrasound probe 6 further comprises a support frame 65. The support frame 65 is used for mounting the ultrasonic probe 6 on the inner side wall of the cup portion 1, and the sequence of the layers of the ultrasonic probe 6 from the detected organ to the inner side wall of the cup portion 1 is as follows: an acoustic lens layer 61, a matching layer 62, a piezoelectric sensor array layer 63, and a backing material layer 64, in this embodiment, the backing material layer 64 of the ultrasonic probe 6 is mounted on a support frame 65, that is, the piezoelectric sensor array layer 63 is located between the matching layer 62 and the backing material layer 64. The acoustic lens layer 61, matching layer 62 and piezoelectric sensor array layer 63 are mounted on a support frame 65 by a backing material layer 64.
When the optical ultrasonic breast cancer detector is used, the patient wears the optical ultrasonic breast cancer detector provided by the embodiment:
in the aspect of the dynamic scattering optical module, as the CCD camera 3 is also arranged in the cup part 1, L ED light source 5 is needed for irradiation, the pressurizing air bag 4 pressurizes a detected organ, namely a breast, the surface of the pressurizing air bag is tightly attached to the surface of the detected organ to compress the detected organ, meanwhile, the CCD camera 3 moves on the slide rail 2 to collect breast transmitted light information from different directions, and then image reconstruction is carried out through an imaging system to form a precise three-dimensional functional image.
In the aspect of the ultrasonic piezoelectric detection module, as shown in fig. 3, since the ultrasonic detection requires the assistance of a couplant, the couplant in the couplant bag 7 enters the cup portion 1 through the couplant conduit 8, and since the optical ultrasonic breast cancer detector is worn, the couplant entering the cup portion 1 can be naturally extruded in a narrow space and smeared on the surface of the organ to be detected. And the couplant in the couplant bag 7 can enter the cup part 1 in a manual extrusion mode, a conveying device can be additionally arranged on the couplant bag 7, the couplant is automatically injected according to the set demand of the couplant, and the couplant in the cup part 1 can be recovered to the couplant bag 7 through the conveying device after use. The transfer of fluids, such as coupling agents, is not limited herein, as is known in the art. When ultrasonic detection is carried out, ultrasonic wave transmitting sequences of a plurality of ultrasonic probes 6 and ultrasonic wave receiving sequences of the plurality of ultrasonic probes 6 are preset, according to the preset, the ultrasonic probes 6 which transmit ultrasonic waves, the ultrasonic probes 6 which receive the ultrasonic waves receive transmitted ultrasonic waves 66 and/or reflected ultrasonic waves 67, tomography is carried out on the mammary gland, the mammary gland is detected in an all-around mode, accurate three-dimensional images are formed, and judgment of a doctor on the position of the mammary gland tumor is improved. The sequence of the ultrasonic probes 6 for transmitting ultrasonic waves and the sequence of the ultrasonic probes 6 for receiving ultrasonic waves can be flexibly set by a doctor according to actual clinical needs, and are not limited herein. Compared with the existing ultrasonic examination, generally, the ultrasonic examination is of a supination type, the handheld ultrasonic probe is clung to the breast skin for detection, the ultrasonic image mainly takes two-dimensional imaging, and the breast tissue is soft, so that the breast can deform along with the extrusion of the probe, and the conventional ultrasonic examination method cannot accurately image.
When the optical ultrasonic breast cancer detector provided by this embodiment is used, the two modalities may be imaged simultaneously or separately, which is not limited herein.
The optical ultrasonic breast cancer detector provided by the embodiment fuses the dynamic scattering optical imaging mode and the ultrasonic mode, autonomous tomography is performed in a standing state of a patient to form an accurate three-dimensional image, the dynamic scattering optical image can be obtained while the three-dimensional image of the ultrasonic morphological structure is provided, tumor metabolic function information is obtained, information from various imaging sources can be comprehensively expressed on one image, diagnosis accuracy is improved, a doctor can conveniently know the comprehensive condition of tumor tissues or organs, more accurate diagnosis is made or a more scientific and optimized treatment scheme is made, meanwhile, the patient does not need to be rolled to multiple positions for detection, burden of the patient is reduced, and diagnosis efficiency is improved.
Example two
As shown in fig. 5 and 6, the present embodiment provides a medical apparatus, and the medical apparatus 9 includes the optical ultrasonic breast cancer detector described in embodiment 1.
The host part of the medical device 9 is connected with the optical ultrasonic breast cancer detector in a wired or wireless manner, when the medical device is connected in a wired manner, the optical ultrasonic breast cancer detector is directly powered by the medical device 9, when the medical device is connected in a wireless manner, a battery is used for powering the optical ultrasonic breast cancer detector, the host part of the medical device 9 controls the L ED light source to irradiate and the action part of the optical ultrasonic breast cancer detector to act, namely the CCD camera 3 of the dynamic scattering optical module moves on the sliding rail 2 and the pressurizing air bag 4 pressurizes the detected organ, and simultaneously controls the detection part of the optical ultrasonic breast cancer detector, namely the CCD camera 3 and the ultrasonic probe 6 to detect, the dynamic scattering optical signals collected by the CCD camera 3 and the ultrasonic signals collected by the ultrasonic probe 6 are transmitted to the host part of the medical device 9 in a wired or wireless transmission manner, wherein the dynamic optical images 91 are images reflecting the function information of tumor metabolism, and the ultrasonic images 92 are three-dimensional images reflecting the accurate tumor position.
While the present invention has been described with reference to the preferred embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. Any modification which does not depart from the functional and structural principles of the present invention is intended to be included within the scope of the claims.

Claims (10)

1. An optical ultrasonic breast cancer detector comprises a cup portion and is characterized by further comprising a dynamic scattering optical module and an ultrasonic piezoelectric detection module, wherein the dynamic scattering optical module is used for collecting dynamic scattering optical signals, the ultrasonic piezoelectric detection module is used for collecting ultrasonic signals, the dynamic scattering optical module comprises a CCD camera, the ultrasonic piezoelectric detection module comprises an ultrasonic probe, and the ultrasonic probe and the CCD camera are located on the inner side of the cup portion.
2. The optical ultrasonic breast cancer detector of claim 1, wherein: the dynamic scattering optical module further comprises a pressurizing air bag used for pressurizing the detected organ, the pressurizing air bag is positioned between the inner side wall of the cup part and the detected organ, the area covering the inner side wall of the cup part is smaller than the area of the inner side wall of the cup part, and the maximum distance of the pressurizing air bag in the height direction of the cup part is smaller than the height of the cup part.
3. The optical ultrasound breast cancer monitor of claim 2, wherein said dynamic scattering optics module further comprises L ED light sources for providing light to said dynamic scattering optics module, said L ED light sources being distributed on the inside walls of said cup portions between said pressurizing bladder and the inside walls of said cup portions.
4. The optical ultrasonic breast cancer detector of claim 2, wherein: the dynamic scattering optical module also comprises a laser light source for providing illumination for the dynamic scattering optical module, and the laser light source is distributed on the inner side wall of the cup part and is positioned between the pressurizing air bag and the inner side wall of the cup part.
5. The optical ultrasonic breast cancer detector of claim 1, wherein: the CCD camera is a pinhole camera, the dynamic scattering optical module comprises a sliding rail arranged on the inner side of the cup part, and the CCD camera moves on the sliding rail.
6. The optical ultrasonic breast cancer detector of claim 2, wherein: the ultrasonic probes are distributed on the inner side wall, which is not covered by the pressurizing air bag, in the cup part, and the ultrasonic probes sequentially comprise an acoustic lens layer, a matching layer, a piezoelectric sensor array layer and a backing material layer from the detected organ to the inner side wall of the cup part.
7. The optical ultrasonic breast cancer detector of claim 6, wherein: the ultrasonic probe also includes a support frame for mounting it on the inside walls of the cup portions, the backing material layer being mounted on the support frame.
8. The optical ultrasonic breast cancer detector of claim 6, wherein: the ultrasonic piezoelectric detection module further comprises a couplant sac and a couplant conduit, wherein the couplant sac is located outside the cup portion, and the couplant in the couplant sac enters the cup portion through the couplant conduit.
9. A medical apparatus, characterized in that it comprises an optical ultrasound breast cancer detector according to any one of claims 1 to 8.
10. The medical device of claim 9, wherein: the dynamic scattering optical module and the ultrasonic piezoelectric detection module transmit signals to the medical equipment, and the medical equipment performs imaging according to the signals.
CN202010342848.8A 2020-04-27 2020-04-27 Optical ultrasonic breast cancer detector and medical equipment Pending CN111407237A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010342848.8A CN111407237A (en) 2020-04-27 2020-04-27 Optical ultrasonic breast cancer detector and medical equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010342848.8A CN111407237A (en) 2020-04-27 2020-04-27 Optical ultrasonic breast cancer detector and medical equipment

Publications (1)

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CN111407237A true CN111407237A (en) 2020-07-14

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Application Number Title Priority Date Filing Date
CN202010342848.8A Pending CN111407237A (en) 2020-04-27 2020-04-27 Optical ultrasonic breast cancer detector and medical equipment

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