CN111358600A - Self-locking intervertebral fusion device system under spinal endoscope - Google Patents
Self-locking intervertebral fusion device system under spinal endoscope Download PDFInfo
- Publication number
- CN111358600A CN111358600A CN202010198435.7A CN202010198435A CN111358600A CN 111358600 A CN111358600 A CN 111358600A CN 202010198435 A CN202010198435 A CN 202010198435A CN 111358600 A CN111358600 A CN 111358600A
- Authority
- CN
- China
- Prior art keywords
- self
- locking
- fusion
- system under
- main body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
Abstract
The invention provides a self-locking interbody fusion cage system under a spinal endoscope, which comprises a fusion cage main body, self-locking lag screws, a fusion cage holder and screw handles, wherein the self-locking lag screws are connected to the fusion cage main body, the fusion cage holder is used for connecting and operating the fusion cage main body, the screw handles are connected and operating the self-locking lag screws, and the self-locking interbody fusion cage system is suitable for lumbar fusion under the spinal endoscope. The invention is used for solving the problems of lower fusion rate of the intervertebral fusion cage and further reduction of trauma in the lumbar vertebra fusion process under the assistance of the endoscope, avoids the insufficiency of autogenous bones in the operation process, can effectively improve the fusion efficiency under the percutaneous endoscope assistance, and greatly improves the operation safety.
Description
Technical Field
The invention belongs to the field of spinal minimally invasive fusion, relates to a percutaneous spinal endoscopic auxiliary lumbar fusion technology, and particularly relates to a self-locking intervertebral fusion device system under a spinal endoscope, which is used for realizing the instant stabilization of an implanted intervertebral fusion device and a vertebral body by means of self-locking lag screws when the intervertebral fusion device is placed into an intervertebral space in the minimally invasive fusion operation process.
Background
The lumbar intervertebral fusion (Endo-LIF) under the assistance of endoscope is one of the minimal invasive fusion techniques of the present accurate treatment lumbar degenerative disease, can reach the clinical curative effect consistent with the classic minimal invasive lumbar intervertebral foramen intervertebral fusion, incision and tissue damage are less, postoperative does not have drainage, the recovery is faster, local anesthesia can be accomplished, more importantly, the intervertebral space can be handled under the direct vision in the art, reduce the damage of cartilage end plate, avoid the early collapse of intervertebral space. However, the existing problems are that the operation efficiency is still low, the fusion speed of the intervertebral fusion cage is slow, the fixation needs to be matched with a percutaneous pedicle screw, and the like, and the development of the technology is limited. Clinical and scientific research focus is to realize the quick fixed of intervertebral space on the basis of present interbody fusion cage, reduces the fixed of rear percutaneous screw, and this will improve operation security and efficiency greatly.
Disclosure of Invention
The invention aims to provide a self-locking interbody fusion cage system under a spinal endoscope, which is used for solving the problem of how to put an interbody fusion cage into a vertebral body after decompression of the spinal endoscope to realize rapid stabilization.
In order to solve the technical problems, the invention adopts the following technical scheme:
the utility model provides a self-locking interbody fusion cage system under backbone scope, includes fusion cage main part, self-locking lag screw, fusion cage holder and screw handle, self-locking lag screw connects fuse in the ware main part, fusion cage holder is used for connecting and operates the installation fuse the ware main part, screw handle connects and operates the installation self-locking lag screw, this self-locking interbody fusion cage system is applicable to lumbar vertebrae fusion art under the backbone scope. The self-locking interbody fusion cage system has the advantages of strong supporting strength, self-locking tension design and high bone fusion efficiency.
Furthermore, the top surface and the bottom surface of the fusion device main body are in an outer convex arc shape, the front end of the fusion device main body is in a bullet head shape, the tail end of the fusion device main body is in a round blunt shape, a rectangular through hole is formed in the center of the fusion device main body, a groove is formed in the outer portion of the tail end of the fusion device main body and used for being connected with the fusion device holder, and two threaded nail holes are formed in the inner portion of the tail end of; the top surface is a barbed porous structure, and the side surface is also provided with a plurality of side holes.
Wherein the length of the fusion device body is 23 or 25cm, the height is 8, 10, 12 or 14mm, and the width is 10 mm.
Still further, two nail holes are the slope setting, and the incline direction is different. One of which is inclined inwardly and the other is inclined outwardly.
Furthermore, the far end of the self-locking lag screw is in a self-tapping hollow design, the thread space is tight, the width is gradually increased towards the near end, and the near end is in a self-locking design and is matched with a nail hole at the tail end of the fusion device main body.
Wherein, the diameter of the self-locking lag screw is 4.5, 5.5 or 6.5mm, and the length is 16 mm.
Furthermore, the fusion cage holder is made of stainless steel, the front end of the fusion cage holder is connected with the groove at the tail end of the fusion cage body, the tail end of the fusion cage holder is in a spiral design, the tail end of the fusion cage holder is tightly connected with the fusion cage body when the fusion cage holder rotates clockwise, and the tail end of the fusion cage holder is separated when the fusion cage holder rotates anticlockwise.
Wherein, the length of the fusion device holder is 330mm, and the diameter is 8 mm.
Furthermore, the screw handle is hollow cylindrical, and can be firmly fixed with the vertebral body after the self-locking lag screw is sent into the screw hole along the guide wire.
The diameter of the joint of the screw handle and the self-locking lag screw is 4.0mm, and the diameter of the main body part is 4.5mm, so that the screw implantation under the endoscope can be realized.
Compared with the prior art, the invention has the advantages and positive effects that:
the intervertebral fusion cage is suitable for being used under a spinal endoscope, reduces the medical cost and ensures the safety of patients; the fusion cage and the self-locking tension screw assembly which are specially designed can realize decompression, fusion and internal fixation in a single surgical incision, thereby greatly improving the surgical efficiency; the self-locking interbody fusion cage system under the assistance of the spinal endoscope can replace the fusion cage used clinically at present, and has wide clinical application prospect.
The research and development of the self-locking interbody fusion cage system become a development direction of the spine endoscope-assisted fusion in the future.
Other features and advantages of the present invention will become more apparent from the detailed description of the embodiments of the present invention when taken in conjunction with the accompanying drawings.
Drawings
The invention will be further described with reference to the accompanying drawings and examples, in which:
FIG. 1 is a schematic structural diagram of a main body of a self-locking interbody fusion cage system under a spinal endoscope according to the present invention;
FIG. 2 is a schematic structural view of a self-locking lag screw in the self-locking interbody fusion cage system under the spinal endoscope of the present invention;
FIG. 3 is a schematic structural view of a cage holder in the self-locking intervertebral cage system under spinal endoscopy according to the present invention;
fig. 4 is a structural schematic view of a screw handle in the self-locking interbody fusion cage system under the spinal endoscope.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail with reference to the accompanying drawings and examples. It should be understood that the embodiments described herein are merely illustrative of the present invention and are not intended to limit the present invention.
The invention aims to provide a self-locking interbody fusion cage system under a spinal endoscope, which is used for solving the problem of how to put an interbody fusion cage into a vertebral body after decompression of the spinal endoscope to realize rapid stability. The self-locking interbody fusion cage system has the advantages of strong support strength, self-locking tension design and high bone fusion efficiency, can effectively improve the fusion efficiency under a percutaneous endoscopic auxiliary mirror, and greatly improves the safety of the operation. In particular, the amount of the solvent to be used,
referring to fig. 1-4, the present embodiment provides a self-locking interbody fusion cage system under a spinal endoscope, which includes a fusion cage main body 10, a self-locking lag screw 20, a fusion cage holder 30 and a screw handle 40, wherein the self-locking lag screw 20 is connected to the fusion cage main body 10, the fusion cage holder 30 is used for connecting and operatively installing the fusion cage main body 10, the screw handle 40 is connected and operatively installing the self-locking lag screw 20, and the self-locking interbody fusion cage system is suitable for lumbar fusion under a spinal endoscope.
As shown in fig. 1, the top surface 11 and the bottom surface 12 of the fusion device main body 10 are of convex arc shapes, the front end 13 is of a bullet head shape, the tail end 14 is of a round blunt shape, the center of the fusion device main body is provided with a rectangular through hole 15, the outer part of the tail end is provided with a groove 16 for connecting a fusion device holder 30, and the inner part of the tail end is provided with two threaded nail holes 17 for matching with a self-locking lag screw 20; two of the nail holes 17 are obliquely arranged and have different oblique directions, wherein one of the nail holes is obliquely inwards and the other nail hole is obliquely outwards. The top surface 11 of the fusion device main body 10 is of a barb-shaped porous structure and is provided with a plurality of barbs 11-1, a plurality of through holes 11-2 are formed between the barbs, the side surface is a plane, and a plurality of side holes 18 including rectangular side holes and circular side holes are also formed on the side surface. The fusion body 10 resembles a flat honeycomb structure as a whole. The cage body 10 is 23 or 25cm in length, 8, 10, 12 or 14mm in height and 10mm in width.
As shown in fig. 2, the distal end 21 of the self-locking lag screw 20 is self-tapping hollow, the thread pitch is compact, the width gradually increases towards the proximal end 22, the proximal end 22 is self-locking, and the self-locking lag screw 20 is matched with the nail hole 17 at the tail end of the fusion device main body 10. Wherein, the diameter of the self-locking lag screw 20 can adopt 4.5, 5.5 or 6.5mm, and the length is 16 mm.
As shown in fig. 3, the cage holder 30 is made of stainless steel, the front end 31 is connected to the groove 16 at the rear end of the cage body, and the rear end 32 is of a spiral design, so that the rear end of the cage holder 30 is tightly connected to the cage body 10 when rotated clockwise, and the rear ends are separated when rotated counterclockwise. Wherein, the length of the fusion device holder 30 is 330mm, and the diameter thereof is 8 mm.
As shown in fig. 4, the screw handle 40 is hollow cylinder, and can be firmly fixed with the vertebral body after the self-locking lag screw 20 is sent into the screw hole 17 along the guide wire. The diameter of the joint of the screw handle 40 and the self-locking lag screw 20 is 4.0mm, and the diameter of the main body part is 4.5mm, so that the screw implantation under the endoscope can be realized.
When in use, in the process of spine endoscope-assisted lumbar fusion operation,
before the system device is used, the percutaneous screw guide wire needs to be pre-implanted; cutting off a zygapophyseal joint at one side by using an endoscopic ring saw, exposing an intervertebral foramen, cutting off ligamentum flavum, decompressing a vertebral canal and a nerve root canal, and exposing an exiting nerve root and a walking root; then, under the endoscope, the intervertebral disc is removed in an auxiliary way, and the cartilage end plate is processed;
after the treatment is ready, the endoscope is required to be replaced, the fusion device is placed along the guide wire and the guide rod is expanded step by step and implanted into the working sleeve, the endoscope is placed, the tip of the outer sleeve is found under the endoscope and is guided to the outer side and the ventral side of the walking root, and after the nerve root is protected, the inner sleeve is rotated 90-180 degrees anticlockwise, so that the exiting nerve root can be fully protected;
selecting a fusion cage main body 10 with a proper size according to the intervertebral space processing condition, placing the stable holder 30 into the intervertebral space by adopting the fusion cage, and enabling the perspective depth of the C-arm machine to be proper;
the endoscope is placed again, the angle is adjusted, the guide wire is placed under the endoscope, the self-locking lag screw 20 is placed under the endoscope by adopting the screw handle 40, and if osteoporosis is combined, a screw with a larger diameter can be placed along the guide wire.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. The utility model provides a self-locking interbody fusion cage system under backbone scope, its characterized in that includes fusion cage main part, auto-locking lag screw, fusion cage holder and screw handle, auto-locking lag screw connects fuse in the ware main part, fusion cage holder is used for connecting and operates the installation fuse the ware main part, the screw handle is connected and is operated the installation auto-locking lag screw, this auto-locking interbody fusion cage system is applicable to lumbar vertebrae fusion art under the backbone scope.
2. The self-locking intervertebral fusion system under spinal endoscope of claim 1, wherein: the top surface and the bottom surface of the fusion device main body are in an outer convex arc shape, the front end of the fusion device main body is in a bullet head shape, the tail end of the fusion device main body is in a round blunt shape, a rectangular through hole is formed in the center of the fusion device main body, a groove is formed in the outer portion of the tail end of the fusion device main body and used for being connected with the fusion device holder, and two threaded nail holes are formed in the inner portion of the tail; the top surface is a barbed porous structure, and the side surface is also provided with a plurality of side holes.
3. The self-locking intervertebral fusion system under spinal endoscopy of claim 2, wherein: the length of the fusion device body is 23 or 25cm, the height is 8, 10, 12 or 14mm, and the width is 10 mm.
4. The self-locking intervertebral fusion system under spinal endoscopy of claim 2, wherein: the two nail holes are obliquely arranged and have different oblique directions.
5. The self-locking intervertebral fusion system under spinal endoscopy of claim 2, wherein: the far end of the self-locking lag screw is designed to be self-tapping hollow, the thread space is tight, the width is gradually increased towards the near end, and the near end is designed to be self-locking and is matched with a nail hole at the tail end of the fusion device main body.
6. The self-locking intervertebral fusion system under spinal endoscope of claim 5, wherein: the diameter of the self-locking lag screw is 4.5mm, 5.5 mm or 6.5mm, and the length of the self-locking lag screw is 16 mm.
7. The self-locking intervertebral fusion system under spinal endoscopy of claim 2, wherein: fuse ware holder is stainless steel, and the front end is connected with fuse ware main part tail end recess, and the end is the spiral design, fuses ware holder tail end and fuse ware main part zonulae occludens when clockwise rotation, and the tail end separation when anticlockwise rotation.
8. The self-locking intervertebral fusion system under spinal endoscopy of claim 7, wherein: the length of the fusion device holder is 330mm, and the diameter of the fusion device holder is 8 mm.
9. The self-locking intervertebral fusion system under spinal endoscopy of claim 2, wherein: the screw handle is hollow cylinder, and can be sent into the nail hole with the auto-lock lag screw along the seal wire after, realizes firm internal fixation with the centrum.
10. The self-locking intervertebral fusion system under spinal endoscopy of claim 9, wherein: the diameter of the joint of the screw handle and the self-locking lag screw is 4.0mm, and the diameter of the main body part is 4.5mm, so that the screw implantation under the endoscope can be realized.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010198435.7A CN111358600A (en) | 2020-03-20 | 2020-03-20 | Self-locking intervertebral fusion device system under spinal endoscope |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010198435.7A CN111358600A (en) | 2020-03-20 | 2020-03-20 | Self-locking intervertebral fusion device system under spinal endoscope |
Publications (1)
Publication Number | Publication Date |
---|---|
CN111358600A true CN111358600A (en) | 2020-07-03 |
Family
ID=71198696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202010198435.7A Pending CN111358600A (en) | 2020-03-20 | 2020-03-20 | Self-locking intervertebral fusion device system under spinal endoscope |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111358600A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112274304A (en) * | 2020-12-21 | 2021-01-29 | 冯万立 | Visual interbody fusion cage of backbone scope |
KR20220159743A (en) * | 2021-05-26 | 2022-12-05 | 주식회사 엔도비전 | Spine surgery instrument |
WO2023243741A1 (en) * | 2022-06-14 | 2023-12-21 | 주식회사 엔도비전 | Spinal surgery device |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6156037A (en) * | 1998-10-28 | 2000-12-05 | Sdgi Holdings, Inc. | Anterior lateral spine cage-plate fixation device and technique |
US20070142921A1 (en) * | 2005-12-21 | 2007-06-21 | Lewis Paul Peter P | Acetabular cup with rigid fasteners |
CN102781373A (en) * | 2009-12-31 | 2012-11-14 | Ldr医疗公司 | Anchoring device, intervertebral implant and implantation instrument |
CN103784190A (en) * | 2012-10-31 | 2014-05-14 | 王国喜 | Minimally invasive composite self-tapping pedicle screw |
US20170071756A1 (en) * | 2009-03-30 | 2017-03-16 | DePuy Synthes Products, Inc. | Zero Profile Spinal Fusion Cage |
CN107184265A (en) * | 2017-07-04 | 2017-09-22 | 中国人民解放军第四军医大学 | Self-taped type is stumbled plate bolt and its application |
US20180014945A1 (en) * | 2005-04-12 | 2018-01-18 | Nathan C. Moskowitz | Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs |
CN108742953A (en) * | 2018-03-19 | 2018-11-06 | 唐小毛 | A kind of minimally invasive double cortex centrum screw self-stabilization type " ear " type lumbar intervertebral fusion devices |
US20180360621A1 (en) * | 2017-01-26 | 2018-12-20 | Soojung Moon | Inserting device of cage for disc space between vertebrae |
CN109806034A (en) * | 2019-03-28 | 2019-05-28 | 西安市红会医院 | Lumbar vertebral posterior interbody cage systems |
CN209122543U (en) * | 2018-01-24 | 2019-07-19 | 深圳市斯玛仪器有限公司 | Invasive lumbar fusion device |
US20200046516A1 (en) * | 2004-03-29 | 2020-02-13 | NuVaisve, Inc. | Systems and methods for spinal fusion |
-
2020
- 2020-03-20 CN CN202010198435.7A patent/CN111358600A/en active Pending
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6156037A (en) * | 1998-10-28 | 2000-12-05 | Sdgi Holdings, Inc. | Anterior lateral spine cage-plate fixation device and technique |
US20200046516A1 (en) * | 2004-03-29 | 2020-02-13 | NuVaisve, Inc. | Systems and methods for spinal fusion |
US20180014945A1 (en) * | 2005-04-12 | 2018-01-18 | Nathan C. Moskowitz | Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs |
US20070142921A1 (en) * | 2005-12-21 | 2007-06-21 | Lewis Paul Peter P | Acetabular cup with rigid fasteners |
US20170071756A1 (en) * | 2009-03-30 | 2017-03-16 | DePuy Synthes Products, Inc. | Zero Profile Spinal Fusion Cage |
CN102781373A (en) * | 2009-12-31 | 2012-11-14 | Ldr医疗公司 | Anchoring device, intervertebral implant and implantation instrument |
CN103784190A (en) * | 2012-10-31 | 2014-05-14 | 王国喜 | Minimally invasive composite self-tapping pedicle screw |
US20180360621A1 (en) * | 2017-01-26 | 2018-12-20 | Soojung Moon | Inserting device of cage for disc space between vertebrae |
CN107184265A (en) * | 2017-07-04 | 2017-09-22 | 中国人民解放军第四军医大学 | Self-taped type is stumbled plate bolt and its application |
CN209122543U (en) * | 2018-01-24 | 2019-07-19 | 深圳市斯玛仪器有限公司 | Invasive lumbar fusion device |
CN108742953A (en) * | 2018-03-19 | 2018-11-06 | 唐小毛 | A kind of minimally invasive double cortex centrum screw self-stabilization type " ear " type lumbar intervertebral fusion devices |
CN109806034A (en) * | 2019-03-28 | 2019-05-28 | 西安市红会医院 | Lumbar vertebral posterior interbody cage systems |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112274304A (en) * | 2020-12-21 | 2021-01-29 | 冯万立 | Visual interbody fusion cage of backbone scope |
KR20220159743A (en) * | 2021-05-26 | 2022-12-05 | 주식회사 엔도비전 | Spine surgery instrument |
KR102559794B1 (en) | 2021-05-26 | 2023-07-26 | 주식회사 엔도비전 | Spine surgery instrument |
WO2023243741A1 (en) * | 2022-06-14 | 2023-12-21 | 주식회사 엔도비전 | Spinal surgery device |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10441318B2 (en) | Additively manufactured systems for low profile spinopelvic fixation and sacroiliac joint fusion for complex spinal deformities | |
US9861496B2 (en) | Apparatus and method of spinal implant and fusion | |
US9649138B2 (en) | Facet screw and method for spinal stabilization | |
CN111358600A (en) | Self-locking intervertebral fusion device system under spinal endoscope | |
US7909871B2 (en) | Devices and methods for inter-vertebral orthopedic device placement | |
US20120323242A1 (en) | Surgical awl and method of using the same | |
CN103889351A (en) | Bone anchors | |
JP2008509753A (en) | Providing treatment to adjacent motion segments | |
WO2009083583A1 (en) | Percutaneous interspinous process spacer | |
US11446065B2 (en) | Self in-fusing pedicle screw implant | |
JP2006521163A (en) | Hybrid interlocking proximal femoral fracture fixation | |
CN103222889B (en) | Bone grafting devic | |
CN216021331U (en) | Anterior cervical steel plate, lifting device and internal fixing system used in ACAF (anterior cervical spine extension) operation | |
CN105943203B (en) | Comprehensive adjustable intervertebral fixes fusion device | |
US11918262B2 (en) | Fixation device and method of using the same | |
CN113786234A (en) | Anterior cervical steel plate, lifting device and internal fixing system used in ACAF (anterior cervical spine extension) operation | |
CN109998656A (en) | Vertebral pedicle nail fixer for cervical vertebrae, fixed system and fixing means | |
CN220404204U (en) | Hollow spinal screw for intervertebral fusion | |
US11529173B1 (en) | Reduction system for spondylolisthesis | |
US11317958B2 (en) | Surgical fixation assembly and methods of use | |
CN211911777U (en) | Vertebral pedicle screw capable of correcting kyphosis deformity and vertebral pedicle screw group | |
US11109894B2 (en) | Apparatus, system, and method for spinal vertebrae stabilization | |
CN201469390U (en) | Double-core bidirectional side-notched screw | |
CN2627996Y (en) | Intervertebral fusion device | |
CN116898641A (en) | Assembly for intervertebral fusion |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200703 |
|
RJ01 | Rejection of invention patent application after publication |