CN111300945A - Medicine packaging bag and preparation process thereof - Google Patents

Medicine packaging bag and preparation process thereof Download PDF

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Publication number
CN111300945A
CN111300945A CN202010289856.0A CN202010289856A CN111300945A CN 111300945 A CN111300945 A CN 111300945A CN 202010289856 A CN202010289856 A CN 202010289856A CN 111300945 A CN111300945 A CN 111300945A
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parts
packaging bag
polyester layer
medicine packaging
weight
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CN202010289856.0A
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Chinese (zh)
Inventor
张辉
肖瑶
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Sichuan Huili Industrial Co Ltd
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Sichuan Huili Industrial Co Ltd
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Priority to CN202010289856.0A priority Critical patent/CN111300945A/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/18—Layered products comprising a layer of synthetic resin characterised by the use of special additives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/18—Layered products comprising a layer of synthetic resin characterised by the use of special additives
    • B32B27/22—Layered products comprising a layer of synthetic resin characterised by the use of special additives using plasticisers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B33/00—Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/02—Physical, chemical or physicochemical properties
    • B32B7/027—Thermal properties
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04—Coating
    • C08J7/06—Coating with compositions not containing macromolecular substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/30—Properties of the layers or laminate having particular thermal properties
    • B32B2307/306—Resistant to heat
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2423/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2423/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2423/04—Homopolymers or copolymers of ethene
    • C08J2423/06—Polyethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2467/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2477/00—Characterised by the use of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Derivatives of such polymers
    • C08J2477/12—Polyester-amides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K13/00—Use of mixtures of ingredients not covered by one single of the preceding main groups, each of these compounds being essential
    • C08K13/02—Organic and inorganic ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00—Specific properties of additives
    • C08K2201/014—Additives containing two or more different additives of the same subgroup in C08K
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/04—Carbon
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/09—Carboxylic acids; Metal salts thereof; Anhydrides thereof
    • C08K5/092—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/13—Phenols; Phenolates

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  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Materials Engineering (AREA)
  • Laminated Bodies (AREA)
  • Wrappers (AREA)

Abstract

The invention discloses a medicine packaging bag and a preparation process thereof, wherein the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, and the aluminized polyester layer comprises the following components in parts by weight: 30-40 parts of polycaprolactone, 20-25 parts of copolyester, 20-30 parts of polyesteramide, 20-25 parts of polyethylene resin, 5-12 parts of butyl hydroxy anisol, 5-8 parts of dibutyl hydroxy toluene and 8-15 parts of citric acid. The invention solves the problem of poor heat resistance of the aluminized polyester layer of the existing packaging film.

Description

Medicine packaging bag and preparation process thereof
Technical Field
The invention relates to the technical field of medicine packaging, in particular to a medicine packaging bag and a preparation process thereof.
Background
Currently, solid drug packaging mainly includes glass bottles, plastic bottles and film packaging. Because the glass bottle and the plastic bottle are rigid and are only suitable for medicines such as medicine granules or powder, the solid bulk drug cannot be solved. Therefore, some solid raw medicines are usually packaged by using packaging bags, the packaging bags are prepared by packaging films, and after the packaging bags are filled with medicines, sealing openings are required to be subjected to plastic packaging treatment.
The heat resistance of the existing packaging bag is poor, so that the sealing opening is gelatinized during plastic packaging, the sealing opening is not tight, thermal decomposition is easily led out when the packaging bag is in a high-temperature condition, and harmful substances can volatilize in the thermal decomposition process of the packaging bag, so that the property of the raw materials can be influenced. The packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, and the polyethylene layer has good heat resistance, and the poor heat resistance of the packaging bag is mainly reflected in the aluminized polyester layer, so that the key for improving the heat resistance of the packaging bag is to improve the heat resistance of the aluminized polyester layer
Disclosure of Invention
The invention aims to provide a medicine packaging bag, which solves the problem that an aluminized polyester layer of the existing packaging film is poor in heat resistance.
In addition, the invention also provides a preparation process of the medicine packaging bag.
The invention is realized by the following technical scheme:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
30-40 parts of polycaprolactone, 20-25 parts of copolyester, 20-30 parts of polyesteramide, 20-25 parts of polyethylene resin, 5-12 parts of butyl hydroxy anisol, 5-8 parts of dibutyl hydroxy toluene and 8-15 parts of citric acid.
The medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
30-40 parts of polycaprolactone, 20-25 parts of copolyester, 20-30 parts of polyesteramide, 20-25 parts of polyethylene resin, 5-12 parts of butyl hydroxy anisol, 5-8 parts of dibutyl hydroxy toluene and 8-15 parts of citric acid.
The polyethylene layer adopts the prior art, and comprises the following components: polyethylene, natural rubber, plasticizers and stabilizers.
In the formulation of the present invention: the polycaprolactone, the copolyester and the polyesteramide are base materials of the aluminized polyester layer, the aluminized polyester layer prepared only by the base materials is poor in heat resistance, the problems of bubbles, warping deformation and gelation are easily caused when the packaging bag is sealed in a plastic package manner, the sealing performance of the seal is poor, and meanwhile, the packaging bag is volatilized to generate toxic substances to influence the drug property of the original drug due to poor heat resistance. The polyethylene resin has good heat resistance, can improve the heat resistance of an aluminized polyester layer to a certain extent, the butyl hydroxy anisole has good heat stability and a certain antioxidant effect, when the butyl hydroxy anisole is matched with citric acid, the citric acid has a reinforcing effect on the heat resistance of the butyl hydroxy anisole, the heat resistance of the butyl hydroxy anisole can be obviously improved, and the dibutyl hydroxy toluene has a certain heat resistance, can assist the butyl hydroxy anisole and the polyethylene resin to a certain extent, and can jointly act to enhance the heat resistance.
The applicant found through long-term tests that: the heat resistance of the butyl hydroxy anisole can be obviously improved by adding the butyl hydroxy anisole and the citric acid in a certain proportion, the heat resistance of the polyethylene resin and the heat resistance of the butyl hydroxy anisole are combined by adding the combined polyethylene resin, the heat resistance of the aluminized polyester layer can be improved, the plastic package requirement of the aluminized polyester layer is met, the plastic seal opening of the package bag is free from the problems of foaming, warping deformation and gelling, and the sealing performance of the opening is good.
According to the invention, the polyethylene resin, the butyl hydroxy anisole, the dibutyl hydroxy toluene and the citric acid are added into the basic raw materials, on one hand, the heat resistance of the polyethylene resin is improved, on the other hand, the heat resistance of the butyl hydroxy anisole can be obviously improved by matching the butyl hydroxy anisole with the citric acid, the polyethylene resin and the butyl hydroxy anisole act together, and then the dibutyl hydroxy toluene is added, so that the heat resistance of the aluminized polyester layer can be improved, the plastic packaging requirement of the aluminized polyester layer is met, the plastic sealing of the plastic sealing opening of the packaging bag is free from the problems of foaming, warping deformation and gelling, and the sealing performance of the opening is good. Thus, the invention solves the problem of poor heat resistance of the aluminized polyester layer of the existing packaging film.
Further, the aluminized polyester layer is composed of the following components in parts by weight:
35 parts of polycaprolactone, 22 parts of copolyester, 25 parts of polyesteramide, 22 parts of polyethylene resin, 12 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 12 parts of citric acid.
Further, the composition also comprises the following components in parts by weight:
3-6 parts of graphene.
The graphene has certain lubricity and high toughness, is not only beneficial to playing a lubricating role when raw materials are mixed, improves the uniform mixing effect of materials, but also can enhance the toughness of the aluminized polyester layer, improves the tensile resistance of the aluminized polyester layer while meeting the heat resistance of the aluminized polyester layer, and prolongs the service life of the aluminized polyester layer.
Further, the composition also comprises the following components in parts by weight:
8-10 parts of cationic polyacrylamide.
The cationic polyacrylamide has a good antistatic effect, can improve the antistatic capacity of the aluminized polyester layer during plastic packaging, ensures that the packaging bag cannot generate static electricity during the plastic packaging process, and improves the stability.
Further, the composition also comprises the following components in parts by weight:
2-5 parts of lead salicylate.
The lead salicylate is a light stabilizer, and because the aluminized polyester layer can be illuminated during plastic packaging, the light stability of the aluminized polyester layer can be improved by adding a certain content of lead salicylate, so that the stability of the aluminized polyester layer during plastic packaging is improved.
A preparation process of a medicine packaging bag comprises the following steps:
1) weighing materials: weighing the components in parts by weight respectively;
2) mixing materials: uniformly mixing polycaprolactone, copolyester and polyesteramide, adding polyethylene resin under a stirring state, uniformly mixing, adding dibutyl hydroxy toluene, uniformly stirring to form a component A, uniformly mixing butyl hydroxy anisole and citric acid according to a proportion to form a component B, pouring the component B into the component A, and uniformly mixing;
3) and extrusion molding: extruding the uniformly mixed materials at 380-420 ℃ by a double-rod screw extruder to prepare a polyester material;
4) and preparing a film: preparing a polyester film from a polyester material on a film preparation machine;
5) and aluminizing: aluminizing the polyester film by adopting a spraying technology to prepare an aluminized polyester layer;
6) and compounding: compounding an aluminum plated polyester layer and a polyethylene layer to prepare a medicine packaging film;
7) and (3) bag making: and preparing the medicine packaging film into a packaging bag.
Compared with the prior art, the invention has the following advantages and beneficial effects:
according to the invention, the polyethylene resin, the butyl hydroxy anisole, the dibutyl hydroxy toluene and the citric acid are added into the basic raw materials, on one hand, the heat resistance of the polyethylene resin is improved, on the other hand, the heat resistance of the butyl hydroxy anisole can be obviously improved by matching the butyl hydroxy anisole with the citric acid, the polyethylene resin and the butyl hydroxy anisole act together, and then the dibutyl hydroxy toluene is added, so that the heat resistance of the aluminized polyester layer can be improved, the plastic packaging requirement of the aluminized polyester layer is met, the plastic sealing of the plastic sealing opening of the packaging bag is free from the problems of foaming, warping deformation and gelling, and the sealing performance of the opening is good. Thus, the invention solves the problem of poor heat resistance of the aluminized polyester layer of the existing packaging film.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples, and the exemplary embodiments and descriptions thereof are only used for explaining the present invention and are not used as limitations of the present invention.
Example 1:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
40 parts of polycaprolactone, 25 parts of copolyester, 30 parts of polyesteramide, 20 parts of polyethylene resin, 5 parts of butyl hydroxy anisole, 5 parts of dibutyl hydroxy toluene and 8 parts of citric acid.
Example 2:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
30 parts of polycaprolactone, 20 parts of copolyester, 20 parts of polyesteramide, 25 parts of polyethylene resin, 10 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 15 parts of citric acid.
Example 3:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
35 parts of polycaprolactone, 22 parts of copolyester, 25 parts of polyesteramide, 22 parts of polyethylene resin, 12 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 12 parts of citric acid.
Example 4:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
35 parts of polycaprolactone, 22 parts of copolyester, 25 parts of polyesteramide, 22 parts of polyethylene resin, 12 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 12 parts of citric acid; 3 parts of graphene.
Example 5:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
35 parts of polycaprolactone, 22 parts of copolyester, 25 parts of polyesteramide, 22 parts of polyethylene resin, 12 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 12 parts of citric acid; 6 parts of graphene and 8 parts of cationic polyacrylamide.
Example 6:
the medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, wherein the aluminized polyester layer comprises the following components in parts by weight:
35 parts of polycaprolactone, 22 parts of copolyester, 25 parts of polyesteramide, 22 parts of polyethylene resin, 12 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 12 parts of citric acid; 4 parts of graphene, 10 parts of cationic polyacrylamide and 5 parts of lead salicylate.
Comparative example 1:
the present example is based on example 3, and differs from example 3 in that: no polyethylene resin is contained.
Comparative example 2:
the present example is based on example 3, and differs from example 3 in that: without butylated hydroxyanisole and citric acid.
Comparative example 3:
the present example is based on example 3, and differs from example 3 in that: the content of the butyl hydroxy anisole is as follows: 3 parts by weight of citric acid, wherein the content of the citric acid is as follows: 20 parts by weight.
Comparative example 4:
the present example is based on example 3, and differs from example 3 in that: the content of the butyl hydroxy anisole is as follows: 15 parts by weight of citric acid, wherein the content of the citric acid is as follows: 5 parts by weight.
The packaging bags prepared in examples 1 to 6 and comparative examples 1 to 4 were subjected to plastic sealing, appearance change of the seal of the packaging bag was observed, and 10 packaging bags were selected for each example for testing, and the results were as follows:
example 1:
no air bubble and gel appear on 10 packaging bag seals, all the packaging bags are slightly warped and deformed, and the sealing is complete.
Example 2:
no air bubbles and gelatinization appear at the 10 packaging bag seals, and slight buckling deformation appears at the 2 seals, and the seals are sealed completely.
Example 3:
no air bubbles, buckling deformation and gelatinization appear at the seal of the 10 packaging bags, and the seal is complete.
Example 4:
no air bubbles, buckling deformation and gelatinization appear at the seal of the 10 packaging bags, and the seal is complete.
Example 5:
no air bubbles, buckling deformation and gelatinization appear at the seal of the 10 packaging bags, and the seal is complete.
Example 6:
no air bubbles, buckling deformation and gelatinization appear at the seal of the 10 packaging bags, and the seal is complete.
Comparative example 1:
no air bubbles appear at the seal of 10 packaging bags, the 10 packaging bags have warpage deformation with different degrees, 6 packaging bags are gelatinized, and 4 packaging bags are incompletely sealed.
Comparative example 2:
no air bubbles appear at the seal of 10 packaging bags, the 10 packaging bags have warpage deformation with different degrees, 5 packaging bags are slightly gelatinized, and 6 packaging bags are incompletely sealed.
Comparative example 3:
no air bubbles appear at the seal of 10 packaging bags, 2 warp deformation appears, 3 slightly gelatinize, and 2 seals are incomplete.
Comparative example 4:
no air bubbles appear at the seal of 10 packaging bags, 3 buckling deformation appears, 2 slight gelatinization appears, and 2 parts are incompletely sealed.
The medicine packing bags of examples 1 to 6 were subjected to a tensile test, and the medicine packing bags were stretched using a tensile machine (CTM8000), and the test results are shown in table 1:
TABLE 1
Figure BDA0002450007250000051
Figure BDA0002450007250000061
From the data in table 1, it can be seen that:
after the graphene is added, the tensile strength is obviously improved, the fracture elongation force is also improved, and the fracture elongation force is the difference value of the fracture tension force and the tension force which begins to deform
A preparation process of a medicine packaging bag comprises the following steps:
1) weighing materials: weighing the components in parts by weight respectively;
2) mixing materials: uniformly mixing polycaprolactone, copolyester and polyesteramide at normal temperature, adding polyethylene resin under stirring, uniformly mixing, heating to 40 ℃, adding dibutyl hydroxy toluene, uniformly stirring to form a component A, uniformly mixing butyl hydroxy anisole and citric acid in proportion to form a component B, pouring the component B into the component A, and uniformly mixing;
3) and extrusion molding: extruding the uniformly mixed materials at 380-420 ℃ by a double-rod screw extruder to prepare a polyester material;
4) and preparing a film: preparing a polyester film from a polyester material on a film preparation machine;
5) and aluminizing: aluminizing the polyester film by adopting a spraying technology to prepare an aluminized polyester layer;
6) and compounding: compounding an aluminum plated polyester layer and a polyethylene layer to prepare a medicine packaging film;
7) and (3) bag making: and preparing the medicine packaging film into a packaging bag.
The above-mentioned embodiments are intended to illustrate the objects, technical solutions and advantages of the present invention in further detail, and it should be understood that the above-mentioned embodiments are merely exemplary embodiments of the present invention, and are not intended to limit the scope of the present invention, and any modifications, equivalent substitutions, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (7)

1. The medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, and is characterized in that the aluminized polyester layer comprises the following components in parts by weight:
30-40 parts of polycaprolactone, 20-25 parts of copolyester, 20-30 parts of polyesteramide, 20-25 parts of polyethylene resin, 5-12 parts of butyl hydroxy anisol, 5-8 parts of dibutyl hydroxy toluene and 8-15 parts of citric acid.
2. The medicine packaging bag sequentially comprises a polyethylene layer and an aluminized polyester layer from inside to outside, and is characterized in that the aluminized polyester layer comprises the following components in parts by weight:
30-40 parts of polycaprolactone, 20-25 parts of copolyester, 20-30 parts of polyesteramide, 20-25 parts of polyethylene resin, 5-12 parts of butyl hydroxy anisol, 5-8 parts of dibutyl hydroxy toluene and 8-15 parts of citric acid.
3. The medicine packaging bag of claim 2, wherein the aluminized polyester layer comprises the following components in parts by weight:
35 parts of polycaprolactone, 22 parts of copolyester, 25 parts of polyesteramide, 22 parts of polyethylene resin, 12 parts of butyl hydroxy anisole, 8 parts of dibutyl hydroxy toluene and 12 parts of citric acid.
4. The medicine packaging bag of claim 1, further comprising the following components in parts by weight:
3-6 parts of graphene.
5. The medicine packaging bag of claim 1, further comprising the following components in parts by weight:
8-10 parts of cationic polyacrylamide.
6. The medicine packaging bag of claim 1, further comprising the following components in parts by weight:
2-5 parts of lead salicylate.
7. A process for preparing a pharmaceutical pack bag according to claim 1 or 2, comprising the steps of:
1) weighing materials: weighing the components in parts by weight respectively;
2) mixing materials: uniformly mixing polycaprolactone, copolyester and polyesteramide, adding polyethylene resin under a stirring state, uniformly mixing, adding dibutyl hydroxy toluene, uniformly stirring to form a component A, uniformly mixing butyl hydroxy anisole and citric acid according to a proportion to form a component B, pouring the component B into the component A, and uniformly mixing;
3) and extrusion molding: extruding the uniformly mixed materials at 380-420 ℃ by a double-rod screw extruder to prepare a polyester material;
4) and preparing a film: preparing a polyester film from a polyester material on a film preparation machine;
5) and aluminizing: aluminizing the polyester film by adopting a spraying technology to prepare an aluminized polyester layer;
6) and compounding: compounding an aluminum plated polyester layer and a polyethylene layer to prepare a medicine packaging film;
7) and (3) bag making: and preparing the medicine packaging film into a packaging bag.
CN202010289856.0A 2020-04-14 2020-04-14 Medicine packaging bag and preparation process thereof Pending CN111300945A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1446247A (en) * 2000-08-11 2003-10-01 生物技术生化学自然包装两合公司 Biodegradable polymeric blend
CN102336042A (en) * 2010-07-16 2012-02-01 中国纺织科学研究院 Polyester composite film and its preparation method
CN105330976A (en) * 2015-12-03 2016-02-17 芜湖品通塑业科技有限公司 Plastic freshness-keeping bag and preparation method thereof
CN109304918A (en) * 2018-11-14 2019-02-05 重庆瑞霆塑胶有限公司 Seasoning bag material film and production method
CN109369873A (en) * 2018-08-24 2019-02-22 东莞市加伏新材料研究院有限公司 A kind of function slurry and its preparation method and application

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Publication number Priority date Publication date Assignee Title
CN1446247A (en) * 2000-08-11 2003-10-01 生物技术生化学自然包装两合公司 Biodegradable polymeric blend
CN102336042A (en) * 2010-07-16 2012-02-01 中国纺织科学研究院 Polyester composite film and its preparation method
CN105330976A (en) * 2015-12-03 2016-02-17 芜湖品通塑业科技有限公司 Plastic freshness-keeping bag and preparation method thereof
CN109369873A (en) * 2018-08-24 2019-02-22 东莞市加伏新材料研究院有限公司 A kind of function slurry and its preparation method and application
CN109304918A (en) * 2018-11-14 2019-02-05 重庆瑞霆塑胶有限公司 Seasoning bag material film and production method

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