CN111279422A - 编码/解码方法、编码/解码器和存储方法、装置 - Google Patents
编码/解码方法、编码/解码器和存储方法、装置 Download PDFInfo
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- CN111279422A CN111279422A CN201880068914.8A CN201880068914A CN111279422A CN 111279422 A CN111279422 A CN 111279422A CN 201880068914 A CN201880068914 A CN 201880068914A CN 111279422 A CN111279422 A CN 111279422A
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- 238000000034 method Methods 0.000 title claims abstract description 94
- 108091026890 Coding region Proteins 0.000 claims abstract description 120
- 238000013507 mapping Methods 0.000 claims description 98
- 150000007523 nucleic acids Chemical group 0.000 claims description 77
- 239000012634 fragment Substances 0.000 claims description 36
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims description 20
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 20
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 claims description 20
- 239000005547 deoxyribonucleotide Substances 0.000 claims description 19
- 125000002637 deoxyribonucleotide group Chemical group 0.000 claims description 19
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 15
- 239000013598 vector Substances 0.000 claims description 13
- 238000001668 nucleic acid synthesis Methods 0.000 claims description 12
- 229930024421 Adenine Natural products 0.000 claims description 10
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims description 10
- 229960000643 adenine Drugs 0.000 claims description 10
- 229940104302 cytosine Drugs 0.000 claims description 10
- 238000012163 sequencing technique Methods 0.000 claims description 10
- 229940113082 thymine Drugs 0.000 claims description 10
- 108020004707 nucleic acids Proteins 0.000 claims description 9
- 102000039446 nucleic acids Human genes 0.000 claims description 9
- 108020004414 DNA Proteins 0.000 claims description 8
- 102000053602 DNA Human genes 0.000 claims description 6
- 230000002194 synthesizing effect Effects 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 3
- 238000004590 computer program Methods 0.000 claims description 2
- 238000013500 data storage Methods 0.000 abstract description 4
- 238000010586 diagram Methods 0.000 description 22
- 238000005516 engineering process Methods 0.000 description 7
- 230000003287 optical effect Effects 0.000 description 3
- 238000011161 development Methods 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 108091081062 Repeated sequence (DNA) Proteins 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000012165 high-throughput sequencing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007480 sanger sequencing Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/20—Sequence assembly
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03M—CODING; DECODING; CODE CONVERSION IN GENERAL
- H03M7/00—Conversion of a code where information is represented by a given sequence or number of digits to a code where the same, similar or subset of information is represented by a different sequence or number of digits
- H03M7/02—Conversion to or from weighted codes, i.e. the weight given to a digit depending on the position of the digit within the block or code word
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03M—CODING; DECODING; CODE CONVERSION IN GENERAL
- H03M7/00—Conversion of a code where information is represented by a given sequence or number of digits to a code where the same, similar or subset of information is represented by a different sequence or number of digits
- H03M7/30—Compression; Expansion; Suppression of unnecessary data, e.g. redundancy reduction
- H03M7/40—Conversion to or from variable length codes, e.g. Shannon-Fano code, Huffman code, Morse code
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- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Databases & Information Systems (AREA)
- Bioethics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Compression, Expansion, Code Conversion, And Decoders (AREA)
- Compression Or Coding Systems Of Tv Signals (AREA)
Abstract
本公开涉及一种编码/解码方法、编码/解码器和存储方法、装置,涉及数据存储技术领域。该编码方法包括:根据第一二进制代码序列的第一位、第二二进制代码序列的第一位和参考符号,确定编码序列的第一位,参考符号为四种不同符号中的任一种;根据第一二进制代码序列的当前位、第二二进制代码序列的当前位和编码序列的前一位,确定编码序列的当前位,编码序列的当前位为除编码序列的第一位以外的其它位。本公开能够提高存储密度,并避免在编码序列中出现的高GC、高AT重复问题。
Description
PCT国内申请,说明书已公开。
Claims (23)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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CN2017110099002 | 2017-10-25 | ||
CN201711009900 | 2017-10-25 | ||
PCT/CN2018/103795 WO2019080653A1 (zh) | 2017-10-25 | 2018-09-03 | 编码/解码方法、编码/解码器和存储方法、装置 |
Publications (2)
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CN111279422A true CN111279422A (zh) | 2020-06-12 |
CN111279422B CN111279422B (zh) | 2023-12-22 |
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US (1) | US20200321079A1 (zh) |
CN (1) | CN111279422B (zh) |
WO (1) | WO2019080653A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113539371A (zh) * | 2021-07-05 | 2021-10-22 | 南方科技大学 | 一种序列的编码方法及装置、可读存储介质 |
Families Citing this family (1)
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CN114758703B (zh) * | 2022-06-14 | 2022-09-13 | 深圳先进技术研究院 | 基于重组质粒dna分子的数据信息存储方法 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1463497A (zh) * | 2001-06-06 | 2003-12-24 | 精工爱普生株式会社 | 解码器、解码方法、查用表和解码程序 |
US20060068405A1 (en) * | 2004-01-27 | 2006-03-30 | Alex Diber | Methods and systems for annotating biomolecular sequences |
CN101565746A (zh) * | 2009-06-03 | 2009-10-28 | 东南大学 | 带奇偶校验的信号组合编码dna连接测序方法 |
CN104850760A (zh) * | 2015-03-27 | 2015-08-19 | 苏州泓迅生物科技有限公司 | 带有编码信息的人工合成dna存储介质及信息的存储读取方法和应用 |
CN105022935A (zh) * | 2014-04-22 | 2015-11-04 | 中国科学院青岛生物能源与过程研究所 | 一种利用dna进行信息存储的编码方法和解码方法 |
CN105550570A (zh) * | 2015-12-02 | 2016-05-04 | 深圳市同创国芯电子有限公司 | 一种应用于可编程器件的加密、解密方法及装置 |
CN106022006A (zh) * | 2016-06-02 | 2016-10-12 | 广州麦仑信息科技有限公司 | 一种将基因信息进行二进制表示的存储方法 |
CN106845158A (zh) * | 2017-02-17 | 2017-06-13 | 苏州泓迅生物科技股份有限公司 | 一种利用dna进行信息存储的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2875458A2 (en) * | 2012-07-19 | 2015-05-27 | President and Fellows of Harvard College | Methods of storing information using nucleic acids |
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2018
- 2018-09-03 WO PCT/CN2018/103795 patent/WO2019080653A1/zh active Application Filing
- 2018-09-03 CN CN201880068914.8A patent/CN111279422B/zh active Active
-
2020
- 2020-04-24 US US16/858,295 patent/US20200321079A1/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1463497A (zh) * | 2001-06-06 | 2003-12-24 | 精工爱普生株式会社 | 解码器、解码方法、查用表和解码程序 |
US20060068405A1 (en) * | 2004-01-27 | 2006-03-30 | Alex Diber | Methods and systems for annotating biomolecular sequences |
CN101565746A (zh) * | 2009-06-03 | 2009-10-28 | 东南大学 | 带奇偶校验的信号组合编码dna连接测序方法 |
CN105022935A (zh) * | 2014-04-22 | 2015-11-04 | 中国科学院青岛生物能源与过程研究所 | 一种利用dna进行信息存储的编码方法和解码方法 |
CN104850760A (zh) * | 2015-03-27 | 2015-08-19 | 苏州泓迅生物科技有限公司 | 带有编码信息的人工合成dna存储介质及信息的存储读取方法和应用 |
CN105550570A (zh) * | 2015-12-02 | 2016-05-04 | 深圳市同创国芯电子有限公司 | 一种应用于可编程器件的加密、解密方法及装置 |
CN106022006A (zh) * | 2016-06-02 | 2016-10-12 | 广州麦仑信息科技有限公司 | 一种将基因信息进行二进制表示的存储方法 |
CN106845158A (zh) * | 2017-02-17 | 2017-06-13 | 苏州泓迅生物科技股份有限公司 | 一种利用dna进行信息存储的方法 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113539371A (zh) * | 2021-07-05 | 2021-10-22 | 南方科技大学 | 一种序列的编码方法及装置、可读存储介质 |
CN113539371B (zh) * | 2021-07-05 | 2023-06-23 | 南方科技大学 | 一种序列的编码方法及装置、可读存储介质 |
Also Published As
Publication number | Publication date |
---|---|
CN111279422B (zh) | 2023-12-22 |
US20200321079A1 (en) | 2020-10-08 |
WO2019080653A1 (zh) | 2019-05-02 |
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