CN111265769A - Drip-permeation electric infusion hot compress transdermal infusion apparatus - Google Patents
Drip-permeation electric infusion hot compress transdermal infusion apparatus Download PDFInfo
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- CN111265769A CN111265769A CN202010253078.XA CN202010253078A CN111265769A CN 111265769 A CN111265769 A CN 111265769A CN 202010253078 A CN202010253078 A CN 202010253078A CN 111265769 A CN111265769 A CN 111265769A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
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- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a drip-infiltration electric-infusion hot-compress transdermal infusion apparatus, which is characterized in that a medicine infiltration layer, an electric-infusion hot-compress net, a dropper and a cover fixing film are sequentially arranged on the skin of a human body from the epidermis to the outside; the electric conduction hot compress net comprises an electric conduction net and an electric heating net; the electric conduction network is connected with an electric lead-in regulator R through a lead2Introduction of electricity into regulator R2Upper series electric leading-in switch K2Conducting electricity to the switch K2And is conducted to a power supply V2In series, to a power supply V2A variable electrode S is connected on the upper part; the electric heating net is connected with a thermistor R through a lead1Thermistor R1Upper series electric heating switch K1Electrothermal switch K1And an electric heating power supply V1Are connected in series; the dropper is provided with a dropper hole which is opposite to the position between the medicine seepage layer and the cover fixing film. The invention can continuously transdermal administer different liquid medicines according to the pathology, accelerate the transdermal absorption and the administration dosage of the medicine according to the needs and change the administration varieties.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a drip-infiltration electric infusion hot-compress transdermal infusion apparatus.
Background
The skin is the largest organ of the human body. Transdermal drug delivery has the advantages of small damage to digestive systems, particularly livers, no degradation of the drug effect of the digestive systems to drugs, safe and convenient use, targeted slow release and the like, is a leading-edge technology which is very important in the medical field at present, and is mostly applied to the molded drug preparations such as inunction, ointment, plaster, gel and the like.
The iontophoresis administration at acupuncture points is a prior art for introducing drugs into acupuncture points by direct current, but has the defects of complicated operation, insufficient administration amount, incapability of continuous administration and the like.
The drip infiltration technology is a mature agricultural technology for supplying water and fertilizer to planting.
Disclosure of Invention
The invention aims to provide a drip-infiltration electric infusion hot compress transdermal infusion apparatus, which can continuously transdermal administer different liquid medicines according to pathology, accelerate the transdermal absorption and administration dosage of the medicines according to needs, and replace the administration varieties so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a drip-infiltration electric-infusion hot-compress transdermal infusion apparatus comprises a medicine infiltration layer, an electric-infusion hot-compress net, a dropper and a cover fixing film; the medicine seepage layer, the electric conduction hot compress net, the dropper and the cover fixing film are sequentially arranged on the skin of the human body from the epidermis to the outside and are fixed on the skin of the human body by the cover fixing film; the electric conduction hot compress net comprises an electric conduction net and an electric heating net; the electric conduction network is connected with an electric lead-in regulator R through a lead2Introduction of electricity into regulator R2Upper series electric leading-in switch K2Conducting electricity to the switch K2And is conducted to a power supply V2In series, to a power supply V2A variable electrode S is connected on the upper part; the electric heating net is connected with a thermistor R through a lead1Thermistor R1Upper series electric heating switch K1Electrothermal switch K1And an electric heating power supply V1Are connected in series; the dropper is provided with a dropper hole which is opposite to the position between the medicine seepage layer and the cover fixing film.
Preferably, the medicine permeating layer is a belt-shaped, block-shaped or body-fitted garment made of microporous noise reduction cotton and microporous fibers; or elastic socks, elastic gloves or elastic abdominal belts made of absorbent cotton and absorbent gauze.
Preferably, the electric conduction net is formed by weaving metal wires, the electric heating net is formed by weaving electric heating wires, and the electric conduction hot compress net is a conductive electric heating soft woven net which is formed by weaving the electric conduction net and the electric heating net and has the same width and length as the medicine infiltration layer.
Preferably, the liquid inlet end of one end of the dropper is connected with a liquid outlet of a pressure infusion device, and the pressure infusion device is a medical intravenous infusion apparatus except the residual part of a needle head or one of an infusion pump and a medical injector.
Preferably, the cover fixing film is non-woven fabric or plastic film, the medicine permeating layer, the electric conduction hot compress net and the dropper are covered on the skin surface part for treatment or transdermal administration through adhesive glue, and the adhesive glue is waterproof and non-allergic insulating glue.
Preferably, the variable electrode S is a metal plate attached to the waist or the limbs, and the variable electrode S and the electric conduction network form a positive electrode and a negative electrode, and are conducted to the power supply V2Is a direct current motor or a battery.
Preferably, the medicine permeating layer, the electric conduction hot compress net, the dropper and the cover fixing film are of an integrated structure, or the medicine permeating layer, the dropper and the cover fixing film are made into an integrated disposable transdermal transfusion belt or a transdermal transfusion block or a transdermal transfusion garment.
Compared with the prior art, the invention has the following beneficial effects:
1. the drip-seepage electric infusion apparatus for hot compress transdermal infusion can be used for long-term transdermal administration of multiple medicines and different doses, is a novel administration mode, and is particularly suitable for weak patients, old and young patients and patients with severe water shortage due to withered epidermis.
2. The drip infusion is conducted into a hot compress transdermal infusion apparatus, the medication is safe, the digestive system, particularly the liver, is basically not damaged, the medical pain is small, and the medical infection rate is low; also has the advantages of definite curative effect, little degradation of drug effect, targeted slow release and the like.
3. The drip-seepage electric infusion apparatus is introduced into a hot compress transdermal infusion apparatus, has low drug standard and low pharmaceutical requirement, and can develop a new drug preparation comprising water, wine, grease and other solutions, suspensions or emulsions with different volumes.
4. The drip permeation electricity is introduced into a hot compress transdermal infusion apparatus, and strong pressure is injected into the pipe orifice of a dropper to carry out transdermal permeation administration.
5. The drip-infiltration electric conduction hot compress transdermal infusion apparatus can be provided with an electrode at the waist, another electrode is connected to an electric conduction net, the conducted current is adjusted to a micro-induction electric shock, and direct current conduction with the anode and the cathode switched once in 5 minutes is adopted for 40 minutes to stop the electric conduction.
6. The dripping permeation electricity is introduced into a hot compress transdermal infusion apparatus, and hot compress circulation administration can be carried out at the temperature of 40 ℃, for 2 hours, 1 time/2 days and 3 hours/time, and the administration treatment is continuously carried out.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
In the figure: 1. a medicine permeating layer; 2. conducting electricity into a hot compress net; 201. an electric heating net; 202. electrically connecting to a network; 3. a dropper; 301. a dropper hole; 4. covering and fixing the film; r2The electricity is conducted into the regulator; k2The electricity is conducted into the switch; v2Conducting electricity to a power supply; s, a variable electrode; r1A thermistor; k1An electric heating switch; v1And an electric heating power supply.
Detailed Description
The technical scheme in the embodiment of the invention will be made clear below by combining the attached drawings in the embodiment of the invention; fully described, it is to be understood that the described embodiments are merely a few, but not all embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
a drip-infiltration electric-infusion hot-compress transdermal infusion apparatus comprises a medicine infiltration layer 1, an electric-infusion hot-compress net 2, a dropper 3 and a cover fixing film 4; the medicine seepage layer 1, the electric conduction hot compress net 2, the dropper 3 and the cover fixing film 4 are sequentially arranged on the skin of the human body from the epidermis to the outside and are fixed on the skin of the human body by the cover fixing film 4; the electric conduction hot compress net 2 comprises an electric conduction net 202 and an electric heating net 201; the electric conduction network 202 is connected with an electric lead-in regulator R through a lead wire2Introduction of electricity into regulator R2Upper series electric leading-in switch K2Conducting electricity to the switch K2And is conducted to a power supply V2In series, to a power supply V2A variable electrode S is connected on the upper part; the electric heating net 201 is connected with a thermistor R through a lead1Thermistor R1Upper series electric heating switch K1Electrothermal switch K1And an electric heating power supply V1Are connected in series; the dropper 3 is provided with a dropper hole 301 for droppingThe pore 301 is opposite to the drug-permeating layer 1 and the cover fixing film 4.
In the above embodiment, the medicine-permeating layer 1 is used for receiving the medicine liquid dripped by the dropper 3 and uniformly distributing the medicine liquid on the epidermis, so that the medicine liquid is coated on the skin for treatment or transdermal administration, and the medicine liquid is permeated or electrically introduced into the skin and is rapidly permeated into the skin under hot compress; the medicine permeating layer 1 can be a belt-shaped, block-shaped or body-fitted garment made of microporous noise reduction cotton and microporous fibers; or elastic socks, elastic gloves or elastic abdominal belts made of absorbent cotton and absorbent gauze.
In the above embodiment, the electrical conduction net 202 is woven by metal wires, the electric heating net 201 is woven by heating wires, the electrical conduction heat compress net 2 is a conductive electric heat soft woven net which is woven by the electrical conduction net 202 and the electric heating net 201 by metal wires and heating wires and has the same width and length as the medicine infiltration layer 1, wherein the electrical conduction heat compress net 2 can also be a water heating pipe network.
In the above embodiment, the liquid inlet end of one end of the dropper 3 is connected with the liquid outlet of the pressure infusion device, and the pressure infusion device is a medical intravenous infusion apparatus except the remaining part of the needle head, or one of an infusion pump and a medical injector; the liquid medicine with pressure is uniformly dripped on the medicine seepage layer 1 through the drip tube holes 301 on the wall of the drip tube 3 by the pressure transfusion device, wherein the uniform dripping can be adjusted by the aperture size and the number of the front, middle and rear drip tube holes 301 on the side wall of the drip tube 3, and can also be adjusted by the drip tube valve arranged on the drip tube 3.
In the above embodiment, the cover fixing film 4 is made of non-woven fabric and plastic film, and the medicine permeating layer 1, the electric conduction hot compress net 2 and the dropper 3 are covered on the skin surface part for treatment or transdermal administration through the adhesive glue which is a waterproof and non-allergic insulating glue.
In the above embodiment, the variable electrode S is a metal plate attached to the waist or limbs, and the variable electrode S and the electric conduction network 202 form positive and negative poles, and are conducted to the power supply V2Is a direct current motor or a battery.
In the above embodiments, the drug-permeating layer 1, the electrically-conductive hot compress net 2, the dropper 3 and the cover fixing film 4 may be made into an integrated structure, or the drug-permeating layer 1, the dropper 3 and the cover fixing film 4 may be made into an integrated disposable transdermal infusion band or transdermal infusion block or transdermal infusion garment.
In the above embodiments, the speed and amount of the liquid medicine are determined by the degree that the medicine-permeated layer 1 is wet and permeated, and the current intensity of the electric introduction is zero to the highest tolerance of the patient, and generally, the electric stimulation or the micro-induced electrical stimulation is adopted, wherein the configuration of the positive electrode and the negative electrode in the variable electrode S is that the cationic medicine is administered according to the polarity of the medicine, the electric introduction net 202 is connected to the positive electrode, otherwise, the electric introduction net 202 is connected to the positive electrode, and for the medicine (such as the traditional Chinese medicine liquid medicine) with unknown polarity, the positive electrode and the negative electrode can be alternately switched and introduced, wherein the heating temperature of the electric heating net 201 refers to the electric hot.
Referring to fig. 1, when in use, the medicine-permeating layer 1, the electric conduction hot compress net 2 and the dropper 3 are placed on the skin surface part for treatment or transdermal administration, and are fixed by the cover fixing film 4, the pressure transfusion device is connected, the air in the dropper 3 is emptied, the administration speed is adjusted, and the medicine-permeating layer 1 is enabled to moisten the skin for transdermal administration; the electric conduction can be started as required, the electric conduction network 202 is connected with an electrode according to the polarity of the medicine, the anode medicine is connected with a positive electrode, the anion medicine is connected with a negative electrode, the unknown or mixed ion medicine is alternately connected with the positive electrode and the negative electrode, the current intensity is adjusted from 0 to the micro electric shock, the electric conduction through dripping permeation is conducted to transdermal administration, the temperature of the heating surface of the electric heating network 201 is adjusted to be 38-39 ℃, the skin permeability is increased through hot compress, the medicine liquid can be conveniently permeated and absorbed, in the administration process, the administration variety and the dosage can be changed at any time according to the requirement, the medicine can be administered according to diseases, and the dripping permeation hot compress transdermal administration without.
Example two:
the following limb transdermal administration is taken as an example for treating venous blood return disorder, arthritis and health care:
(1) wearing cotton long-tube tight socks on the affected limb, and using the cotton long-tube tight socks as a medicine infiltration layer 1;
(2) wrapping the socks with an electric conduction net 202 of fine copper wires, using a circulating hot water pipeline wrapped outside the electric conduction net 202 as an electric heating net 201 for hot compress, perforating with laser at every 1cm along the pipeline wall and plastic pipelines with the same inner diameter of 3mm
A drip pipe 3 is made of 1-5 micron drip holes, and is wound on the outer side of the electric conduction inlet net 202 along with a smooth hot compress pipe, and the lower end of the electric conduction inlet net is closed;
(3) a daily fresh-keeping plastic film is adopted to tightly cover and fix the medicine seepage layer 1 and the electric conduction hot compress net 2 on the lower limbs;
(4) soaking Ginseng radix 20g in 50% alcohol 100ml, and filtering to obtain Ginseng radix wine solution;
(5) the ginseng wine solution is injected into the dropper 3 by a medical injector to finish the administration.
In summary, the following steps: the drip-seepage electric infusion apparatus for hot compress transdermal infusion can be used for long-term multiple times of transdermal administration of various medicines and different doses, is a novel administration mode, and is particularly suitable for weak patients, old and young patients and patients with severe water shortage due to withered epidermis; secondly, the invention has safe medication, basically no harm to digestive system, especially liver, little medical pain and low medical infection rate; the medicine also has the advantages of definite curative effect, less degradation of the drug effect, targeted slow release and the like, the medicine standard of the medicine is low, the pharmaceutical requirement is low, a new medicine preparation comprising water, wine, grease and other solutions with different volumes, suspension or emulsion can be developed, and strong pressure is injected into the pipe orifice of the dropper 3 for transdermal infiltration administration; in addition, the waist of the invention can be provided with an electrode, the other electrode is connected to the electric conduction net 202, the current is adjusted to be conducted to the micro-induction electric shock, the direct current with the anode and the cathode converted once in 5 minutes is conducted for 40 minutes to stop the electric conduction, and the hot compress cyclic administration can be carried out at the temperature of 40 ℃, for 2 hours, for 1 time/2 days and for 3 hours/time, and the administration treatment is continued.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the term "includes"; "comprises," "comprising," or any other variation thereof, is intended to cover a non-exclusive inclusion, such that a process that comprises a list of elements; a method; an article or apparatus may comprise not only those elements but also other elements not expressly listed or embodied as such; a method; an article or an apparatus.
Although embodiments of the present invention have been shown and described, it would be appreciated by those skilled in the art that changes may be made in these embodiments without departing from the principles and spirit of the invention; modifying; alternatives and modifications, the scope of the invention being defined by the appended claims and equivalents thereof.
Claims (7)
1. A drip-infiltration electric-infusion hot-compress transdermal infusion apparatus comprises a medicine infiltration layer (1), an electric-infusion hot-compress net (2), a dropper (3) and a cover fixing film (4); the method is characterized in that: the medicine seepage layer (1), the electric conduction hot compress net (2), the dropper (3) and the cover fixing film (4) are sequentially arranged on the skin of the human body from the epidermis to the outside and are fixed on the skin of the human body by the cover fixing film (4); the electric conduction hot compress net (2) comprises an electric conduction net (202) and an electric heating net (201); the electric conduction network (202) is connected with an electric conduction regulator R through a lead wire2Introduction of electricity into regulator R2Upper series electric leading-in switch K2Conducting electricity to the switch K2And is conducted to a power supply V2In series, to a power supply V2A variable electrode S is connected on the upper part; the electric heating net (201) is connected with a thermistor R through a lead1Thermistor R1Upper series electric heating switch K1Electrothermal switch K1And an electric heating power supply V1Are connected in series; the dropper (3) is provided with a dropper hole (301), and the dropper hole (301) is just opposite to the space between the medicine seepage layer (1) and the cover fixing film (4).
2. A drip infusion transdermal delivery device according to claim 1, wherein: the medicine permeating layer (1) is a belt-shaped, block-shaped or body-fitted garment made of microporous silencing cotton and microporous fibers; or elastic socks, elastic gloves or elastic abdominal belts made of absorbent cotton and absorbent gauze.
3. A drip infusion transdermal delivery device according to claim 1, wherein: the electric conduction net (202) is formed by weaving metal wires, the electric heating net (201) is formed by weaving electric heating wires, and the electric conduction hot compress net (2) is a conductive electric heating soft woven net which is formed by weaving the electric conduction net (202) and the electric heating net (201) by adopting metal wires and electric heating wires and has the same width and length as the medicine infiltration layer (1).
4. A drip infusion transdermal delivery device according to claim 1, wherein: the liquid inlet end of one end of the dropper (3) is connected with the liquid outlet of a pressure infusion device, and the pressure infusion device is a medical intravenous infusion apparatus except the rest part of a needle head or one of an infusion pump and a medical injector.
5. A drip infusion transdermal delivery device according to claim 1, wherein: the cover fixing film (4) is non-woven fabric and plastic film, the medicine permeating layer (1), the electric conduction hot compress net (2) and the dropper (3) are covered on the skin surface part for treatment or transdermal administration through adhesive glue, and the adhesive glue is waterproof and non-allergic insulating glue.
6. A drip infusion transdermal delivery device according to claim 1, wherein: the variable electrode S is a metal plate attached to the waist or limbs, and the variable electrode S and the electric conduction net (202) form a positive electrode and a negative electrode, and the electric conduction net is electrically connected with a power supply V2Is a direct current motor or a battery.
7. A drip infusion transdermal delivery device according to claim 1, wherein: the medicine permeating layer (1), the electric conduction hot compress net (2), the dropper (3) and the cover fixing film (4) are of an integrated structure, or the medicine permeating layer (1), the dropper (3) and the cover fixing film (4) are made into an integrated disposable transdermal infusion belt or transdermal infusion block or transdermal infusion clothes.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010253078.XA CN111265769A (en) | 2020-04-02 | 2020-04-02 | Drip-permeation electric infusion hot compress transdermal infusion apparatus |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010253078.XA CN111265769A (en) | 2020-04-02 | 2020-04-02 | Drip-permeation electric infusion hot compress transdermal infusion apparatus |
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| CN111265769A true CN111265769A (en) | 2020-06-12 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4474570A (en) * | 1981-07-10 | 1984-10-02 | Kabushikikaisya Advance Kaihatsu Kenkyujo | Iontophoresis device |
| CN87215752U (en) * | 1987-11-24 | 1988-11-16 | 关治躬 | Dropper type medicine ion therapeutic apparatus |
| CN2179162Y (en) * | 1994-02-25 | 1994-10-12 | 丁承国 | Chinese medicine externally leading-in device for human body |
| US20080045910A1 (en) * | 2003-05-30 | 2008-02-21 | Hang Chun Chau | Hot medical Compress Apparatus |
| CN108553749A (en) * | 2018-05-15 | 2018-09-21 | 咸阳张森医疗仪器有限公司 | A kind of iontophoresis therapeutic instrument for vaginitis |
| CN108635677A (en) * | 2018-05-25 | 2018-10-12 | 张婷 | A kind of joint protecting casing that section being immunized suitable for rheumatism |
-
2020
- 2020-04-02 CN CN202010253078.XA patent/CN111265769A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4474570A (en) * | 1981-07-10 | 1984-10-02 | Kabushikikaisya Advance Kaihatsu Kenkyujo | Iontophoresis device |
| CN87215752U (en) * | 1987-11-24 | 1988-11-16 | 关治躬 | Dropper type medicine ion therapeutic apparatus |
| CN2179162Y (en) * | 1994-02-25 | 1994-10-12 | 丁承国 | Chinese medicine externally leading-in device for human body |
| US20080045910A1 (en) * | 2003-05-30 | 2008-02-21 | Hang Chun Chau | Hot medical Compress Apparatus |
| CN108553749A (en) * | 2018-05-15 | 2018-09-21 | 咸阳张森医疗仪器有限公司 | A kind of iontophoresis therapeutic instrument for vaginitis |
| CN108635677A (en) * | 2018-05-25 | 2018-10-12 | 张婷 | A kind of joint protecting casing that section being immunized suitable for rheumatism |
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