CN111257526B - Analytical instrument for bladder cancer treatment target preparation - Google Patents
Analytical instrument for bladder cancer treatment target preparation Download PDFInfo
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- CN111257526B CN111257526B CN202010168732.7A CN202010168732A CN111257526B CN 111257526 B CN111257526 B CN 111257526B CN 202010168732 A CN202010168732 A CN 202010168732A CN 111257526 B CN111257526 B CN 111257526B
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- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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Abstract
The invention belongs to the field of bladder cancer tumor-resisting medicament analyzers, and particularly relates to an analyzer and a method for a bladder cancer treatment target spot preparation. The analyzer for the anti-bladder cancer tumor target medicament aluminum sulfate is targeted, has high control precision on an analysis solution of aluminum sulfate, clear ordered and hierarchical control process steps, and accurate judgment, control and grasp of an analysis end point, is simple and concise, has low cost compared with other electronic analyzers, is convenient and easy to master and popularize in a using method and an analysis mode, and has wide application in the field of anti-bladder cancer tumors.
Description
Technical Field
The invention belongs to the field of bladder cancer tumor-resisting medicament analytical instruments, and particularly relates to an instrument and a method for a bladder cancer treatment target preparation.
Background
Bladder cancer is a malignant tumor which is common in our lives in recent years, the bladder cancer has great harm to human health, and the existing medical level of China is that methods for treating bladder cancer are various, and the existing treatment methods have high cost, long treatment course and poor effect, so that a medicament for treating bladder cancer is urgently needed at present to solve the urgent need of cancer patients. One of the targeted drug therapies is, the release military medical college bulletin, 1981 (2), discloses that aluminum sulfate has better curative effect when used for treating bladder tumor by intratumoral injection, and the cure rate of early bladder tumor is 91.1%. Later-stage further research shows that the compound aluminum sulfate injection has a certain treatment effect on early bladder tumors, but the existing instrument for analyzing the anti-bladder cancer tumor target preparation aluminum sulfate is an existing common analyzing and titrating instrument which has no pertinence, the control precision of the aluminum sulfate analysis solution is not high, the control process is unclear, the analysis endpoint cannot be accurately judged, controlled and grasped, the analysis and judgment of the effective content of the anti-bladder cancer tumor target preparation aluminum sulfate are influenced, the existing other electronic analysis instruments for the anti-bladder cancer tumor target preparation are expensive in equivalent, complex in operation and difficult to popularize and use, and therefore the development of bladder cancer tumor treatment is seriously influenced.
Disclosure of Invention
In order to solve one of the problems, the invention provides an analyzer for a bladder cancer treatment target spot preparation, which comprises a liquid storage device, a liquid separation channel and an analysis controller, wherein the lower end of the liquid storage device is communicated with one end of the liquid separation channel, the other end of the liquid separation channel is communicated with the analysis controller, and the analysis controller realizes precise separation and precise control on an analysis liquid through a modeling and moving control structure.
Preferably, the volume of the liquid reservoir is not less than that of the analysis controller, the liquid reservoir and the analysis controller are arranged in parallel, the effective liquid level of the liquid reservoir is not lower than the highest liquid level of the analysis controller, and the liquid reservoir, the liquid separation channel and the analysis controller form
A font structure, the analysis controller is arranged at
The right side of the glyph to facilitate light entry and analytical control.
Preferably, the reservoir is a container having the same cross-sectional shape at any position along the vertical direction independent portion and the same cross-sectional area at any position along the vertical direction independent portion, and the reservoir is composed of at least a depletion volume part and a scalar volume part, and the depletion volume part and the scalar volume part are both provided with identification lines for discrimination.
Preferably, the liquid separation channel comprises a control valve, the control valve is arranged in the center of the liquid separation channel, the size of the liquid separation channel is not more than 1/3 of the diameter and the length of the corresponding liquid reservoir, and the control valve is a grinding valve.
Preferably, the analysis controller includes the intercommunication funnel, the intercommunication switch, the buffer, and the district is arranged to the quantitative liquid, and liquid accurate control mechanism, fluidic nozzle constitute, the intercommunication funnel lower extreme is connected and is set up the intercommunication switch, the buffer is connected to the intercommunication switch, buffer, quantitative liquid are arranged district, liquid accurate control mechanism top-down and are linked together in proper order, liquid accurate control mechanism lower extreme is connected the intercommunication fluidic nozzle and is constituted analysis controller in order to realize the control analysis.
Preferably, the height of the communicating funnel does not exceed the height of the loss volume part of the liquid reservoir, the communicating switch is a ground valve, the communicating funnel and the communicating switch are integrally formed, the buffer area is in an arc-shaped expanding shape, the quantitative liquid discharge area is in an arc-shaped expanding filling shape structure, and the liquid fine control mechanism is realized by measuring a piston container.
Preferably, the arc-shaped expanding filling modeling structure of the quantitative liquid discharge area comprises an arc-shaped expanding container, an arc-shaped expanding container filling body and an arc-shaped expanding annular space formed by the arc-shaped expanding container and the arc-shaped expanding container filling body, annular space liquid level indicating lines are arranged above and below the arc-shaped expanding container filling body, and at least one unit scale volume of the scalar volume part is equal to the volume of the annular space.
Preferably, the measuring piston container comprises a piston container body, the volume of the piston container cannot exceed the volume of the arc-shaped expanding annular space, and the piston container is internally provided with a measuring track, a moving adjusting piston matched with the measuring track, a moving handle connected with the moving adjusting piston and a control switch.
Preferably, a lamp which is directly projected downwards is arranged on the jet nozzle, and the movable handle is provided with a light reflecting material, so that the operation of reflecting light to prompt an analyst to stop when the color of the terminal point of analysis is changed can be better realized.
Preferably, the measuring track is a plurality of right-angled triangle shapes, the right-angled sides of the right-angled triangle shapes are tangent to the inner wall of the container body, so that the measuring track formed by the oblique angles of the right-angled triangle shapes is formed, the piston moves along the track and is clamped between measuring track chutes formed by two oblique sides, the movable adjusting piston is formed by elastic sealing materials, one end of the elastic sealing materials moves and forms liquid amount precise control with the measuring track and the measuring track chutes thereof, a moving handle arranged at the center of the movable adjusting piston is used for realizing the power of up-and-down movement, the liquid amount can be circulated and the upward return of the movable adjusting piston can be realized by pressing a control switch connected close to the end of the movable piston, and particularly, the movable adjusting piston forms control of liquid amount forming unit precise subdivision by each time of the measuring track formed by the oblique angle of one right-angled triangle shape.
The invention also provides a method for analyzing the anti-tumor target preparation by the analysis instrument, which comprises the steps of firstly, adding the analysis liquid of the analyzed anti-tumor target preparation into the liquid storage device to the mark line of the volume consumption part of the liquid storage device, opening the control valve of the liquid distribution channel, adjusting the movable adjusting piston to the measuring track near the liquid level indicating line under the arc-shaped expanding container filling body, and pressing and opening the control switch of the movable adjusting piston to enable the liquid in the volume consumption part to flow into and fill the liquid distribution channel, the liquid precision control mechanism and the jet nozzle; secondly, opening a communicating switch of the analysis controller to enable one unit of scale liquid in the scalar volume part of the liquid reservoir to flow into and fully occupy the liquid level indicating line in the volume of the annular space, and closing or controlling a liquid separation channel control valve; and finally, pressing a control switch of the movable adjusting piston, moving a movable handle connected with the movable adjusting piston to enable the movable adjusting piston to move downwards along each measuring track to flow out each unit precision liquid, and recording the number of the moved measuring tracks until the analyzed anti-tumor target point preparation reaches an analysis terminal point to realize the precise analysis and control of the analysis liquid.
The invention has the beneficial effects that:
the analyzer for the anti-bladder cancer tumor target medicament aluminum sulfate is targeted, has high control precision on an analysis solution of aluminum sulfate, ordered and clear control process steps, and accurate judgment, control and grasping of an analysis end point, is simple and concise, has low cost compared with other electronic analyzers, is convenient and easy to master and popularize in a using method and an analysis mode, and has wide application in the field of anti-bladder cancer tumors.
Drawings
FIG. 1: the invention is a schematic overall structure diagram of the analytical instrument;
FIG. 2: the structure of the quantitative liquid discharge area part of the analytical instrument is shown schematically;
FIG. 3: the invention discloses a structural schematic diagram of a liquid precise control mechanism part of an analytical instrument.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1-3, an analyzer for a bladder cancer therapy target preparation includes a liquid reservoir 1, a liquid separation channel 2, and an analysis controller 3, wherein a lower end of the liquid reservoir 1 is communicated with one end of the liquid separation channel 2, another end of the liquid separation channel 2 is communicated with the analysis controller 3, and the analysis controller 3 implements precise control of an analysis liquid through a modeling and movement control structure.
The volume of the liquid accumulator 1 is not less than that of an analysis controller, the liquid accumulator and the analysis controller are arranged in parallel, the effective liquid level of the liquid accumulator is not lower than the highest liquid level of the analysis controller, and the liquid accumulator, the liquid distribution channel and the analysis controller form
Font structureThe analysis controller is arranged at
The right side of the glyph to facilitate ray entry and analytical control.
The reservoir is a container with the same cross section shape at any position along the vertical direction independent part and the same cross section area at any position along the vertical direction independent part, such as a cylinder, and is at least composed of a loss volume part 11 and a scalar volume part 12, wherein the loss volume part 11 and the scalar volume part 12 are both provided with distinguishing identification lines, and the volume of the loss volume part is not less than the sum of the volumes of the liquid distribution channel 2, the liquid fine control mechanism and the jet nozzle. The volume of the lost volume fraction is calculated somewhat from the liquid required near the end of the analysis of the anti-bladder tumor target agent being analyzed, e.g., aluminum sulfate assay liquid.
The liquid separation channel comprises a control valve 21, the control valve 21 is arranged in the center of the liquid separation channel 2, the size of the liquid separation channel is not more than 1/3 of the diameter and the length of the corresponding liquid accumulator 1, and the control valve 21 is preferably a mill-cut valve.
Analytical control ware 3 includes intercommunication funnel 31, intercommunication switch 32, buffer 33, and quantitative liquid arranges district 34, liquid accurate control mechanism 35, and fluidic nozzle 36 constitutes, intercommunication funnel 31 lower extreme is connected and is set up intercommunication switch 32, intercommunication switch connects buffer 33, quantitative liquid arranges district 34, liquid accurate control mechanism 35 top-down and communicates in proper order, liquid accurate control mechanism 35 lower extreme is connected the intercommunication fluidic nozzle and is constituted analytical control ware in order to realize the control analysis.
The height of the communication funnel 31 does not exceed the height of the liquid reservoir loss volume part 11, the communication switch 32 is a ground valve, the communication funnel and the communication switch are integrally formed, the buffer area 33 is in an arc-shaped expanding shape, the quantitative liquid discharge area 34 is in an arc-shaped expanding filling shape structure, and the liquid fine control mechanism 35 is realized through a measuring piston container 351.
As shown in fig. 2, the arc-shaped expanding filling structure of the quantitative liquid discharge area comprises an arc-shaped expanding container 341, an arc-shaped expanding container filling body 342 and an arc-shaped expanding annular space 343 formed by the arc-shaped expanding container and the arc-shaped expanding container filling body. Annular space liquid level indicating lines, upper indicating lines 3421 and lower indicating lines 3422 are arranged above and below the filling body of the arc-shaped expanding container, at least one unit scale volume of the scalar volume part is equal to the volume of the annular space, and for example, at least one unit scale of the scalar volume part is 1ml.
As shown in fig. 3, the measuring piston container 351 includes a piston container body, the volume of the piston container cannot exceed the volume of the arc-shaped expanding annular space 343, a measuring track 352, a moving adjusting piston 353 matched with the measuring track 352, a moving handle 354 connected with the moving adjusting piston, and a control switch mechanism 355 are arranged in the piston container, the frosted surface on the corresponding side of the measuring track of the plug container provides better sealing and elasticity for the moving adjusting piston, a downward-directed lamp 37 is arranged on the jet nozzle, and the moving handle is provided with a reflecting material 3541, so that when the color change reaching the analysis end point is better realized, the operation of stopping the moving handle to stop the moving of the light-reflecting prompt analyst is realized.
The measuring track 352 is a plurality of right triangle shapes, the right-angled sides of the right triangle shapes are tangent to the inner wall of the container body, the measuring track formed by the oblique angles of the right triangle shapes enables the piston to move along the track and is clamped between measuring track chutes formed by two oblique sides, the moving adjusting piston 353 is formed by elastic sealing materials, one end of each elastic sealing material moves and forms liquid amount precise control with the measuring track and the measuring track chutes thereof, the moving handle arranged at the center of the moving adjusting piston is used for realizing the power of up-and-down movement, the control switch connected to the end of the moving adjusting piston is pressed to realize liquid amount circulation and upward return of the moving adjusting piston, specifically, the measuring track formed by the oblique angle of each right triangle shape forms the control of liquid amount forming unit subdivision precision, for example, 1ml is divided into 0.1ml by each measuring track.
Firstly, adding an analyzed solution of the analyzed anti-tumor target preparation into a liquid storage device to an identification line of a volume consumption part of the liquid storage device, opening a liquid separation channel control valve, adjusting a movable adjusting piston to a measurement track near a liquid level indication line under a filler of an arc-shaped expanding container, and pressing and opening a movable adjusting piston control switch to enable the liquid in the volume consumption part to flow into and fill the liquid separation channel, the liquid precision control mechanism and the jet nozzle; secondly, opening a communicating switch of the analysis controller to enable one unit of scale liquid in the scalar volume part of the liquid reservoir to flow into and fully occupy the liquid level indicating line in the volume of the annular space, and closing or controlling a liquid separation channel control valve; and finally, pressing a control switch of the movable adjusting piston, moving a movable handle connected with the movable adjusting piston to enable the movable adjusting piston to move downwards along each measuring track to flow out each unit precision liquid, and recording the number of the moved measuring tracks until the analyzed anti-tumor target point preparation reaches an analysis terminal point to realize the precise analysis and control of the analysis liquid. Further, a lamp which is directly projected downwards is arranged on the jet nozzle, and when the color changes when the analysis end point is reached, the stop operation of the arrival of the analysis end point is prompted when the reflection material arranged on the movable handle reflects light and irradiates; and further, opening or controlling the liquid separation channel control valve again, opening the analysis controller communication switch, pressing the opening movement adjusting piston control switch again, moving a moving handle connected with the adjusting piston to enable the movement adjusting piston to move upwards along each measuring track to the measuring track near the lower liquid level indicating line of the arc-shaped expanding container filling body, and operating again to perform fine analysis and fine control. The using method of the instrument is simple and convenient and concise in analysis mode.
The cooperation of the integral composition structure of the analyzer realizes the fine control and operation effects of the analyzer, and the analysis controller realizes the fine control of the analysis liquid through a modeling and moving control structure. Annular space liquid level indicating lines are arranged above and below the arc-shaped expanding container filling body, a downward direct light is arranged on the jet nozzle, the movable handle is provided with a reflective material, so that the operation of reflecting light to prompt an analyst to stop the movement of the movable handle is better realized when the color of an analysis end point is changed, and the movable adjusting piston forms the control of the liquid amount with unit subdivision precision through a measurement track formed by an oblique angle of a right-angled triangular body model.
The above-mentioned embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements made to the technical solution of the present invention by those skilled in the art without departing from the spirit of the present invention shall fall within the protection scope defined by the claims of the present invention.
Claims (2)
1. An analytical instrument for a bladder cancer treatment target preparation, characterized in that: the device comprises a liquid storage device, a liquid separation channel and an analysis controller, wherein the lower end of the liquid storage device is communicated with one end of the liquid separation channel, the other end of the liquid separation channel is communicated with the analysis controller, and the analysis controller is provided with a modeling and moving control structure; the volume of the liquid accumulator is not less than that of the analysis controller, the liquid accumulator and the analysis controller are arranged in parallel, the effective liquid level of the liquid accumulator is not lower than the highest liquid level of the analysis controller, and the liquid accumulator, the liquid separation channel and the analysis controller form
A font structure, the analysis controller is arranged at
The right side of the character pattern is convenient for light incidence and analysis control; the reservoir is a container with the same cross section shape at any position along the vertical independent part and the same cross section area at any position along the vertical independent part, the reservoir at least consists of a loss volume part and a scalar volume part, and the loss volume part and the scalar volume part are both provided with distinguishing identification lines; the liquid separation channel comprises a control valve, the control valve is arranged in the center of the liquid separation channel, the diameter and the length of the liquid separation channel are not more than 1/3 of the diameter and the length of the corresponding liquid accumulator, and the control valve is a ground valve; the analysis controller comprises a communicating funnel, a communicating switch, a buffer area, a quantitative liquid discharge area, a liquid precise control mechanism and a jet nozzle, wherein the lower end of the communicating funnel is connected with the communicating switch, the communicating switch is connected with the buffer area, the quantitative liquid discharge area and the liquid precise control mechanism are sequentially communicated from top to bottom, and the lower end of the liquid precise control mechanism is connected with the jet nozzle to form the analysis controller so as to realize control analysis; the height of the communicating funnel does not exceed the height of the loss volume part of the liquid accumulator, the communicating switch is a ground valve, the communicating funnel and the communicating switch are integrally formed, the buffer area is in an arc-shaped expanding shape, the quantitative liquid discharge area is in an arc-shaped expanding filling shape structure, and the liquid precise control mechanism is realized by measuring a piston container; the arc-shaped expanding filling modeling structure of the quantitative liquid discharge area comprises an arc-shaped expanding container, an arc-shaped expanding container filling body and an arc-shaped expanding annular space formed by the arc-shaped expanding container and the arc-shaped expanding container filling body, annular space liquid level indicating lines are arranged above and below the arc-shaped expanding container filling body, at least one unit scale volume of the scalar volume part is equal to the volume of the annular space, a downward direct-injection lamp is arranged on the jet nozzle, and a movable handle is provided with a reflecting material.
2. The analytical instrument of claim 1, wherein: the measuring piston container comprises a piston container body, the volume of the piston container cannot exceed the volume of the arc-shaped expanding annular space, and the piston container is internally provided with a measuring track, a moving adjusting piston matched with the measuring track, a moving handle connected with the moving adjusting piston and a control switch.
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| CN202010168732.7A CN111257526B (en) | 2020-03-12 | 2020-03-12 | Analytical instrument for bladder cancer treatment target preparation |
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| CN111257526B true CN111257526B (en) | 2022-12-13 |
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