CN111203103A

CN111203103A - Efficient medical treatment experiment cerini dialyser cerini

Info

Publication number: CN111203103A
Application number: CN202010252524.5A
Authority: CN
Inventors: 谷昌德
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-04-01
Filing date: 2020-04-01
Publication date: 2020-05-29

Abstract

The invention relates to the technical field of medical instruments, in particular to a high-efficiency medical experimental dialyzer which mainly comprises an annular groove and a dialysis membrane; the annular groove comprises a bottom wall, a first annular side wall and a second annular side wall, wherein the first annular side wall and the second annular side wall protrude out of the bottom wall; the first annular side wall is opposite to the second annular side wall, the first annular side wall is positioned on the inner side of the second annular side wall, a first through hole is formed in the first annular side wall, a second through hole is formed in the second annular side wall, and a third through hole is formed in the bottom wall; the dialysis membrane is annular when being unfolded to be planar, and is provided with a first section, a second section and a third section which are sequentially connected from inside to outside when being unfolded to be planar, the first section is sleeved on the first annular side wall, the second section covers the bottom wall, and the third section is sleeved on the second annular side wall. Compared with the cylindrical dialysis membrane in dialysis in the prior art, the dialysis membrane is in the shape of a ring groove, so that the dialysis area is larger, and the dialysis efficiency is higher.

Description

Efficient medical treatment experiment cerini dialyser cerini

Technical Field

The invention relates to the technical field of medical instruments, in particular to a high-efficiency medical experiment dialyzer.

Background

Dialysis is one of the commonly used techniques in medical experiments, and is used for replacement of buffer systems, crude purification, concentration, desalination and the like of macromolecular substances such as proteins and the like. The core component of dialysis technology is the dialysis membrane, which is distributed over the pores to allow molecules smaller than the diameter of the pores to diffuse to the other side of the dialysis membrane, and dialysis is thus performed. A dialysis device is required during dialysis.

As shown in fig. 1, the patent of prior patent No. CN102172476 discloses a high-efficiency dialyzer for medical experiments, which comprises a fixed seat 1 and a jacket 2, wherein the fixed seat 1 is a hollow cylindrical body, the jacket 2 is clamped on the outer side wall of the fixed seat 1, holes 4 corresponding to the positions are arranged on the outer side wall of the fixed seat 1 and the jacket 2, a dialysis membrane 3 is unfolded and clamped between the outer side wall of the fixed seat 1 and the jacket 2 during use, and a magnetic stirrer 10 is installed at the inner bottom of the fixed seat 1. In the dialysis experiment, to the inside sample liquid that adds of fixing base 1 to put into the dislysate with whole dialysis set, start magnetic stirrers 10, make each part sample concentration in the fixing base 1 keep even, in order to do benefit to improvement dialysis efficiency.

The above technical solution has at least the following disadvantages: because the dialysis membrane 3 is held between the outer side wall of the fixing seat 1 and the jacket 2, the dialysis membrane 3 is integrally cylindrical when in use, wherein the dialysis area of the dialysis membrane 3 is too small, and the dialysis membrane still has a lifting space, so that the dialysis efficiency is further improved.

Disclosure of Invention

In view of this, the present invention provides a high-efficiency dialyzer for medical experiments, and mainly aims to solve the technical problem of how to increase the dialysis area of a dialysis membrane to improve the dialysis efficiency.

In order to achieve the purpose, the invention mainly provides the following technical scheme:

the embodiment of the invention provides a high-efficiency medical experimental dialyzer, which comprises an annular groove and a dialysis membrane; the annular groove comprises a bottom wall, a first annular side wall and a second annular side wall, wherein the first annular side wall and the second annular side wall protrude out of the bottom wall; the first annular side wall is opposite to the second annular side wall, the first annular side wall is positioned on the inner side of the second annular side wall, a first through hole is formed in the first annular side wall, a second through hole is formed in the second annular side wall, and a third through hole is formed in the bottom wall; the dialysis membrane is provided with a first section, a second section and a third section which are sequentially connected, wherein the first section and the third section are both cylindrical, and the second section is annular; the first section is sleeved on the first annular side wall, the second section covers the bottom wall, and the third section is sleeved on the second annular side wall; wherein the efficient medical experimental dialyzer further comprises an end cap; the end cover is used for pressing a section of the first section, which is far away from the second section, against the top end of the first annular side wall and pressing one end of the third section, which is far away from the second section, against the top end of the second annular side wall; the end cover is provided with a convex cover edge, the cover edge is provided with a positioning button, and the positioning button is provided with a pressing end and an inserting end; a first connecting hole for inserting an insertion end is formed in the second annular side wall, and a handle is arranged on the end cover; the end cover is provided with a liquid injection port which can be opened and closed, and the end cover is also provided with a vibration generator.

By means of the technical scheme, the efficient dialyzer for medical experiments at least has the following beneficial effects:

1. compared with the cylindrical dialysis membrane in dialysis in the prior art, the dialysis membrane is in the shape of a ring groove, so that the dialysis area is larger, and the dialysis efficiency is higher;

2. the volume of the annular groove is adjustable, and when the annular groove with smaller volume is enough to contain the sample liquid, the distance between the first annular side wall and the second annular side wall can be preferably reduced, so that the contact area between the sample liquid and the dialysis membrane can be increased, and the dialysis efficiency is further improved;

3. a positioning button on the end cap can be inserted into the second annular sidewall to secure the end cap so that the end cap does not become loose when the handle on the end cap is lifted.

The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical solutions of the present invention more clearly understood and to implement them in accordance with the contents of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings.

Drawings

Figure 1 is a cross-sectional view of an efficient medical laboratory dialyzer of the prior art;

FIG. 2 is a schematic cross-sectional view of an efficient dialyzer for medical experiments according to an embodiment of the present invention;

FIG. 3 is a schematic diagram of an assembly structure of an efficient dialyzer for medical experiments according to an embodiment of the present invention;

FIG. 4 is a schematic exploded view of the high efficiency dialyzer for medical experiments of FIG. 3;

fig. 5 is a schematic structural diagram of an annular groove formed by the base, the first support rod and the second support rod of the high-efficiency medical experimental dialyzer in fig. 4;

FIG. 6 is a schematic view of the structure of the first support bar;

fig. 7 is a schematic view of the structure of the annular collar.

Reference numerals: 1. an annular groove; 2. a dialysis membrane; 3. an end cap; 4. a vibration generator; 5. an annular collar; 6. supporting legs; 7. a second support bar; 8. a first support bar; 9. a positioning button; 11. a first annular sidewall; 12. a base; 13. a second annular sidewall; 10. a first through hole; 20. a second through hole; 30. a third through hole; 21. a first stage; 22. a second stage; 23. a third stage; 31. a liquid injection port; 32. a handle; 33. a cover rim; 51. an elastic strip; 81. a first retraction lever; 120. a second connection hole; 130. a first connection hole; 121. an outer support ring; 122. a connecting arm; 123. an inner support ring; 511. clamping convex; 512. and (4) a groove.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. It should be noted that, if directional indications (such as up, down, left, right, front, and back … …) are involved in the embodiment of the present invention, the directional indications are only used to explain the relative positional relationship between the components, the movement situation, and the like in a specific posture (as shown in the drawing), and if the specific posture is changed, the directional indications are changed accordingly. In addition, if there is a description of "first", "second", etc. in an embodiment of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature.

As shown in fig. 2 and 3, an embodiment of the present invention proposes an efficient medical experimental dialyzer, which includes an annular groove 1 and a dialysis membrane 2. The annular groove 1 includes a bottom wall, and a first annular side wall 11 and a second annular side wall 13 protruding from the bottom wall. The first annular side wall 11 is opposite the second annular side wall 13. The first annular side wall 11 is located inside the second annular side wall 13. As shown in fig. 5, the first annular sidewall 11 is provided with a first through hole 10, the second annular sidewall 13 is provided with a second through hole 20, and the bottom wall is provided with a third through hole 30. Wherein the dialysis membrane 2 has a first section 21, a second section 22 and a third section 23 connected in sequence. The first and

third sections

21 and 23 are cylindrical, and the second section 22 is annular. The first section 21 is sleeved on the first annular side wall 11, the second section 22 covers the bottom wall, and the third section 23 is sleeved on the second annular side wall 13.

In the above example, since the dialysis membrane 2 is covered on the wall of the annular groove 1, compared with the prior art which is cylindrical in dialysis, the dialysis membrane 2 in the present application has the shape of the annular groove 1, so that the dialysis area is larger and the dialysis efficiency is higher. In addition, the first section 21, the second section 22 and the third section 23 can be sequentially sewn to form a complete dialysis membrane 2, so that the dialysis membrane 2 is covered on the wall of the annular groove 1, and the sealing performance is good, and leakage is avoided.

Here, it should be noted that: the dialysis membrane 2 is covered on the wall of the annular groove 1 and then exposed from the first through hole 10, the second through hole 20 and the third through hole 30, which is the actual dialysis part. The number of the first through holes 10, the second through holes 20 and the third through holes 30 can be multiple, so that the actual dialysis area is further increased, and the dialysis efficiency is improved.

Preferably, the distance between the first annular side wall 11 and the second annular side wall 13 is adjustable, so that the volume of the annular groove 1 is adjustable. The spacing between the first and second

annular side walls

11, 13 may be increased, for example when more sample liquid needs to be accommodated, to increase the volume of the annular groove 1. Wherein, when the smaller volume of the annular groove 1 is enough to contain the sample liquid, the distance between the first annular side wall 11 and the second annular side wall 13 can be preferably reduced, and the main purpose of doing so is: for the same volume of sample liquid, the smaller distance between the first annular side wall 11 and the second annular side wall 13 can increase the contact area of the sample liquid with the dialysis membrane 2, so that the dialysis area of the dialysis membrane 2 can be increased, and the improvement of the dialysis area of the sample liquid is facilitated.

As shown in fig. 4 and 5, the aforementioned efficient medical laboratory dialyzer may include a base 12 and a first support rod 8. The first support rods 8 are arranged on the base 12 and are in a plurality. The plurality of first support bars 8 are arranged in a circular pattern on the base 12 to define the first annular sidewall 11. Wherein, an interval is provided between two adjacent first supporting rods 8 to form the first through hole 10. The aforementioned second annular side wall 13 is disposed on the base 12, and a portion of the base 12 located between the first annular side wall 11 and the second annular side wall 13 constitutes the aforementioned bottom wall. In this example, the first annular side wall 11 is formed by mounting the first support bar 8 on the base 12, and the first through hole 10 is not separately processed, so that at least the process of processing the first through hole 10 is omitted, and the processing cost is saved.

In order to improve the stability of the first annular side wall 11, preferably, a reinforcing rib may be connected between two adjacent first supporting rods 8, and each first supporting rod 8 cooperates with the reinforcing rib to form the first annular side wall 11 of the cylindrical net structure.

Each of the aforementioned first support rods 8 can be relatively close to or far from the second annular side wall 13, so as to achieve the purpose of adjusting the distance between the aforementioned first annular side wall 11 and the second annular side wall 13.

In order to realize the function that each first supporting rod 8 can be relatively close to or far from the second annular sidewall 13, as shown in fig. 4 and 5, a plurality of groups of first connecting holes are provided on the base 12, and the number of the first connecting holes 130 in each group is plural and is distributed in a circle. The first connection hole 130 is used for the insertion of the first support rod 8, and the two can be kept relatively fixed, for example, the two can have the same shape, and after the first support rod 8 is inserted into the first connection hole 130, the two are in transition fit. Among two adjacent groups of first connecting holes, one group of first connecting holes is positioned at the inner side of the other group of first connecting holes. The arrangement of the first connection holes in each group is similar to the structure of concentric circles, and the first connection holes 130 in each group are arranged along one of the concentric circles. In this example, when each first support rod 8 is inserted into a different group of first connection holes 130, the first annular side wall 11 and the second annular side wall 13 formed by each first support rod 8 have different distances, so that the purpose of adjusting the distance between the first annular side wall 11 and the second annular side wall 13 can be achieved.

As shown in fig. 6, one end of each of the first support rods 8 is provided with a first retraction rod 81, so as to be inserted into the first connection hole 130 through the first retraction rod 81. Specifically, by providing the first retraction lever 81 at one end of the first support bar 8, the first retraction lever 81 and the first support bar 8 cooperate to form a step which can limit the depth of the first support bar 8 inserted into the first connection hole 130, so that the depth of the first support bars 8 inserted into the first connection hole 130 is the same, thereby forming the first annular sidewall 11 with a uniform height.

In order to improve the connection stability between the first support rods 8 and the base 12, it is preferable that each first telescopic rod 81 is provided with an external thread, and each first connection hole 130 is provided with an internal thread for engaging with the external thread on the first telescopic rod 81, so that each first support rod 8 can be screwed in the first connection hole 130, thereby facilitating the detachment and installation of the first support rod 8 and having the advantage of convenient processing.

As shown in fig. 5, the base 12 may include an inner support ring 123, an outer support ring 121, and a connecting arm 122. The connecting arm 122 is connected between the inner support ring 123 and the outer support ring 121. The number of the connecting arms 122 is more than two, and the connecting arms are arranged at intervals in sequence. The aforementioned third through hole 30 is formed between two adjacent connecting arms 122. The aforementioned first connection holes 130 are respectively provided on the inner support ring 123 and the connection arms 122.

As shown in fig. 5, the efficient dialyzer for medical experiments further comprises a plurality of second support rods 7, and the second support rods 7 are disposed on the base 12. The second support rods 7 are arranged in a circular pattern on the base 12 to define the second annular sidewall 13. Wherein, there is a space between two adjacent second support rods to form the second through hole 20. In this example, the second annular sidewall 13 is formed by mounting the second support rod 7 on the base 12, and the aforementioned second through hole 20 does not need to be separately processed, so that at least the process of processing the second through hole 20 is omitted, and the processing cost is saved.

As shown in fig. 4, the base 12 may be provided with a plurality of second connection holes 120, and the number of the second connection holes 120 may be a plurality and distributed in a circle. The second connection hole 120 is provided with an internal thread. One end of each second support rod 7 is provided with a second telescopic rod, and the second telescopic rod is provided with an external thread meshed with the internal thread. The second retractable rod and the second support rod 7 are matched to form a step, and the step can limit the depth of the second support rod 7 inserted into the second connecting hole 120, so that the depth of each second support rod 7 inserted into the second connecting hole 120 is the same, and the second annular side wall 13 with the same height is formed. In addition, the second support rod 7 is in threaded connection with the base 12, so that the second support rod 7 is convenient to detach and mount, and the processing is convenient.

Here, it should be noted that: the structure of the second support bar 7 may be the same as that of the first support bar 8, and in particular, refer to the schematic structural diagram of the first support bar 8 in fig. 6.

As shown in fig. 3, a plurality of support legs 6 distributed in a circle may be disposed on the base 12 to provide a stable support for the base 12, and when the efficient dialyzer for medical experiment of the present application is placed in dialysate for dialysis experiment, the support legs 6 are disposed to have a gap between the base 12 and the bottom of the dialysis container, which is beneficial for the dialysis membrane 2 covering the base 12 to participate in the dialysis process.

As shown in fig. 2, both the first section 21 and the third section 23 of the dialysis membrane 2 can be provided with an annular collar 5 at the end close to the second section 22. Wherein, after the dialysis membrane 2 is installed in the annular groove 1, the end of the first segment 21 near the second segment 22 can be referred to as the bottom end of the first segment 21, and the end of the third segment 23 near the first segment 21 of the second segment 22 can be referred to as the bottom end of the third segment 23. In this example, the annular collar 5 sleeved on the bottom end of the first segment 21 can cooperate with the first annular sidewall 11 to clamp and fix the dialysis membrane 2, so as to improve the stability of the dialysis membrane 2 sleeved on the first annular sidewall 11. The annular retainer ring 5 sleeved at the bottom end of the third section 23 can be matched with the second annular side wall 13 to clamp and fix the dialysis membrane 2, so that the stability of the dialysis membrane 2 sleeved on the second annular side wall 13 is improved.

As shown in fig. 2, the ends of the first section 21 and the third section 23, which are far away from the second section 22, may also be both sleeved with an annular collar 5. In particular, the first segment 21 may have a first flange turned over the top end of the first annular side wall 11, on which the annular collar 5 is fitted. In this example, by sleeving the annular collar 5 on the top ends of the first section 21 and the third section 23, there is an effect of further clamping and fixing the dialysis membrane 2.

Preferably, the ring diameter of the annular retainer ring 5 is adjustable, and the annular retainer ring 5 can be adjusted to a suitable ring diameter according to actual needs to be sleeved at the different positions, such as the top end and the bottom end of the first section 21 and the top end and the bottom end of the third section 23.

In order to realize the function of adjusting the circle diameter of the annular clamping ring 5, as shown in fig. 7, the annular clamping ring 5 can be formed by connecting two ends of an elastic strip 51. The side wall of one end of the elastic strip 51 is provided with a clamping protrusion 511, the side wall of the other end of the elastic strip is provided with a plurality of grooves 512, and the grooves 512 are sequentially arranged at intervals along the length direction of the elastic strip 51. The locking protrusion 511 is used to be locked with the groove 512. When the locking protrusions 511 are locked in different grooves 512, the annular retainer ring 5 can have different diameters, and the operation is relatively convenient.

Further, as shown in fig. 2, the efficient medical laboratory dialyzer may further include an end cap 3. The end cap 3 is used for pressing a section of the first section 21 facing away from the second section 22 against the top end of the first annular side wall 11 and pressing an end of the third section 23 facing away from the second section 22 against the top end of the second annular side wall 13. In this example, the end caps 3 press both ends of the dialysis membrane 2, so that the dialysis membrane 2 can be further fixed, and the stability of the installation of the dialysis membrane 2 is improved.

As shown in fig. 2, the aforementioned end cap 3 may be provided with a protruding cap rim 33. The cover rim 33 is provided with a positioning button 9. The specific structure of the positioning button 9 is the prior art, and is not described in detail herein. The positioning button 9 has a pressing end and an insertion end. The second annular sidewall 13 is provided with a first connection hole 130 into which the insertion end is inserted. When the locking device is used, the end cover 3 is covered, the positioning button 9 on the end cover 3 is rotated to the position opposite to the first connecting hole 130, then the positioning button 9 is pressed, the insertion end of the positioning button 9 is inserted into the first connecting hole 130, and therefore the end cover 3 can be fixed on the second annular side wall 13, and the end cover 3 is prevented from being loosened.

The end cap 3 is further provided with a handle 32, because the end cap 3 is fixed on the second annular side wall 13, a user can move the efficient medical experimental dialyzer to a required position by pulling the handle 32 without worrying about the loosening of the end cap 3.

The end cover 3 can be provided with a liquid injection port 31 which can be opened and closed, so that a user can inject sample liquid into the annular groove 1 through the liquid injection port 31 without opening and closing the end cover 3 back and forth, and the sample liquid can be conveniently added and poured out.

The end cover 3 can be also provided with a vibration generator 4, and when the vibration generator 4 works, the sample liquid in the annular groove 1 can vibrate, so that the concentration of the sample liquid at each position in the dialysis process can be kept relatively consistent, and the phenomenon of dialysis efficiency reduction caused by uneven concentration of the sample liquid is prevented.

The working principle of the present invention is described below.

Firstly, assembling the efficient medical experimental dialyzer, specifically, screwing each first support rod 8 and each second support rod 7 on a base 12 to form a first annular side wall 11 and a second annular side wall 13 respectively; the dialysis membrane 2 is then applied on the first annular side wall 11, the bottom wall and the second annular side wall 13; the dialysis membrane 2 is fixed by an annular collar 5; then the end cover 3 is covered, one end of the dialysis membrane 2 is pressed and fixed at the top end of the first annular side wall 11 by the end cover 3, and the other end of the dialysis membrane 2 is pressed and fixed at the top end of the second annular side wall 13; then the handle 32 is pulled up to move the efficient medical experimental dialyzer into the dialysis solution; the liquid pouring port 31 is opened, and the sample liquid is added into the annular groove 1.

Here, it should be noted that: in the case of no conflict, a person skilled in the art may combine the related technical features in the above examples according to actual situations to achieve corresponding technical effects, and details of various combining situations are not described herein.

The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.

Claims

1. An efficient dialyzer for medical experiments is characterized by comprising an annular groove (1) and a dialysis membrane (2);

the annular groove (1) comprises a bottom wall, a first annular side wall (11) and a second annular side wall (13) which protrude from the bottom wall; the first annular side wall (11) is opposite to the second annular side wall (13), the first annular side wall (11) is positioned on the inner side of the second annular side wall (13), a first through hole (10) is formed in the first annular side wall (11), a second through hole (20) is formed in the second annular side wall (13), and a third through hole (30) is formed in the bottom wall;

the dialysis membrane (2) is provided with a first section (21), a second section (22) and a third section (23) which are sequentially connected, the first section (21) and the third section (23) are both cylindrical, and the second section (22) is annular; the first section (21) is sleeved on the first annular side wall (11), the second section (22) covers the bottom wall, and the third section (23) is sleeved on the second annular side wall (13);

wherein the efficient medical experimental dialyzer further comprises an end cap (3); the end cover (3) is used for pressing one section of the first section (21) departing from the second section (22) against the top end of the first annular side wall (11) and pressing one end of the third section (23) departing from the second section (22) against the top end of the second annular side wall (13); the end cover (3) is provided with a convex cover edge (33), a positioning button (9) is arranged on the cover edge (33), and the positioning button (9) is provided with a pressing end and an inserting end; a first connecting hole (130) for inserting an insertion end is formed in the second annular side wall (13), and a handle (32) is arranged on the end cover (3); the end cover (3) is provided with a liquid injection port (31) which can be opened and closed, and the end cover (3) is also provided with a vibration generator (4).