CN111166522A - Mouse dermis injury modeling tool for medical experiment - Google Patents
Mouse dermis injury modeling tool for medical experiment Download PDFInfo
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- CN111166522A CN111166522A CN202010017950.0A CN202010017950A CN111166522A CN 111166522 A CN111166522 A CN 111166522A CN 202010017950 A CN202010017950 A CN 202010017950A CN 111166522 A CN111166522 A CN 111166522A
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- bottom plate
- modeling tool
- mouse
- plc
- shell
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- 230000006378 damage Effects 0.000 title claims abstract description 35
- 208000027418 Wounds and injury Diseases 0.000 title claims abstract description 21
- 238000002474 experimental method Methods 0.000 title claims abstract description 21
- 208000014674 injury Diseases 0.000 title claims abstract description 21
- 210000004207 dermis Anatomy 0.000 title abstract description 15
- 230000007246 mechanism Effects 0.000 claims abstract description 17
- 238000009434 installation Methods 0.000 claims abstract description 13
- 230000002500 effect on skin Effects 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 4
- 230000005611 electricity Effects 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
- 230000002349 favourable effect Effects 0.000 abstract description 2
- 239000010985 leather Substances 0.000 abstract 2
- 210000002615 epidermis Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 210000003491 skin Anatomy 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 230000037314 wound repair Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 210000003716 mesoderm Anatomy 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Surgery (AREA)
- Animal Husbandry (AREA)
- Instructional Devices (AREA)
Abstract
The invention provides a mouse dermis injury modeling tool for medical experiments, which comprises a bottom plate and a shell, wherein the shell is fixedly arranged on the outer side surface of the bottom plate, the upper surface of the bottom plate is respectively provided with a four-limb fixing mechanism and a trunk fixing mechanism, the outer side surface of the shell is fixedly provided with a mounting rack, a PLC (programmable logic controller) is arranged on the side surface of the mounting rack, and the input end of the PLC is electrically connected with the output end of an external power supply. This mouse genuine leather damage modeling tool that medical science experiments were used, can conveniently fix the mouse through four limbs fixed establishment and truck fixed establishment, thereby avoid the mouse to leap up in disorder after the injury and lose control, the work efficiency has been improved, be favorable to experimental study, the damage instrument passes through the installation piece simultaneously and installs on the slide bar, can conveniently adjust the damage position through adjusting the slide bar, drive the rotation through driving motor and can cut out the genuine leather of equidimension not, the use flexibility has been improved, and the operation is simple, and the use is convenient.
Description
Technical Field
The invention relates to the technical field of medical experiments, in particular to a mouse dermal injury modeling tool for medical experiments.
Background
The skin covers the body surface and sequentially comprises epidermis, dermis and subcutaneous layer from outside to inside. The dermis is differentiated from the mesoderm and is divided into two layers, the papillary layer and the reticular layer, with no distinct boundary between the two layers. The dermis protrudes with numerous papillae and is embedded into the deep surface of the epidermis, which is connected with the superficial fascia through connective tissue fiber bundles. The dermal tissue has the functions of bearing the upper part and the lower part, the upper part bears the epidermis and the lower part opens the subcutaneous tissue, is an important layer of the skin, has structural and functional importance and specificity, and the dermal components can influence the migration, differentiation, adhesion and growth of repair cells and are an important component part for wound repair; by using a part of dermal injury models, the change of each component of the dermis in the wound repair process and the influence of the change on wound healing can be effectively observed.
Most of the existing mouse dermal injury modeling tools for medical experiments can not fix a mouse in the experiment process, the mouse is easy to disorderly jump after being injured and is difficult to control, the tools for damaging the dermis are difficult to adjust, the position of the tools for damaging the dermis can not be flexibly adjusted according to use requirements, the operation is troublesome, and the use is inconvenient.
Disclosure of Invention
The invention aims to solve the problems, and provides a mouse dermis injury modeling tool for medical experiments, which can conveniently fix a mouse through a four-limb fixing mechanism and a trunk fixing mechanism, avoid the mouse from disordering after being injured so as to lose control, improve the working efficiency, and be beneficial to experimental research.
In order to achieve the purpose, the invention adopts the following technical scheme: a mouse dermis damage modeling tool for medical experiments comprises a bottom plate and a shell, wherein the shell is fixedly arranged on the outer side surface of the bottom plate, the upper surface of the bottom plate is respectively provided with a four-limb fixing mechanism and a trunk fixing mechanism, the outer side surface of the shell is fixedly provided with a mounting rack, a PLC (programmable logic controller) is installed on the side surface of the mounting rack, the input end of the PLC is electrically connected with the output end of an external power supply, the lower surface of the mounting rack is fixedly provided with an electric push rod, the input end of the electric push rod is electrically connected with the output end of the PLC, a driving motor is installed inside the telescopic end of the electric push rod, the input end of the driving motor is electrically connected with the output end of the PLC, the output shaft of the driving motor penetrates out of the lower surface of the telescopic end of the electric push rod, slide in the spout and be provided with the slide bar, the bottom outside surface of slide bar has cup jointed the installation piece, and the screw has all been seted up to the side surface of installation piece and the lower part outside surface of slide bar, and screw female connection has fixing bolt, the lower surface of installation piece is provided with the damage instrument, the roof lower surface of mounting bracket is provided with range unit.
As a preferred technical scheme of the present invention, the four-limb fixing mechanism includes four-limb fixing straps uniformly arranged on an upper surface of the base plate, a first hook and loop fastener female surface is sewn on an inner side surface of a movable end of each of the four-limb fixing straps, and a first hook and loop fastener male surface corresponding to the first hook and loop fastener female surface is adhered to a position, close to the four-limb fixing straps, on the upper surface of the base plate.
As a preferred technical scheme of the present invention, the trunk fixing mechanism includes two trunk fixing straps disposed on the upper surface of the base plate, a second hook and loop fastener female surface is sewn on the outer side surface of the movable end of the trunk fixing strap, and a second hook and loop fastener male surface corresponding to the second hook and loop fastener female surface is sewn on the upper surface of the trunk fixing strap.
As a preferred technical scheme of the invention, the upper surface of the bottom plate is provided with an arc-shaped groove close to the movable end of the trunk fixing bandage, and a fixing rod is fixedly arranged in the arc-shaped groove.
According to a preferable technical scheme of the invention, the distance measuring device comprises a laser distance measuring sensor arranged on the lower surface of the top plate of the mounting frame, the output end of the laser distance measuring sensor is electrically connected with the input end of the PLC, and a distance measuring plate corresponding to the laser distance measuring sensor is fixedly arranged on the surface of the telescopic end side of the electric push rod.
As a preferable aspect of the present invention, the outer side surface of the slide bar is threadedly connected with a fastening bolt.
As a preferable technical scheme of the present invention, scale marks are uniformly provided on both sides of the sliding groove on the upper surface of the rotating plate, and a pointer corresponding to the scale marks is provided on the side surface of the top end of the sliding rod.
As a preferable technical scheme of the invention, the upper surface of the bottom plate is provided with a water outlet, and a sealing plug is arranged in the water outlet.
By adopting the technical scheme, the invention has the beneficial effects that: according to the mouse dermis injury modeling tool for medical experiments, disclosed by the invention, a mouse can be conveniently fixed through the four-limb fixing mechanism and the trunk fixing mechanism, the mouse is prevented from disorganizing after being injured and losing control, the working efficiency is improved, experimental research is facilitated, meanwhile, the injury tool is arranged on the sliding rod through the mounting block, the injury position can be conveniently adjusted through adjusting the sliding rod, dermis with different sizes can be cut out through driving the rotation of the driving motor, the use flexibility is improved, the operation is simple, and the use is convenient.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the structure of FIG. 1 at point A according to the present invention;
FIG. 3 is a schematic structural diagram of the base plate of the present invention;
FIG. 4 is a schematic structural view of a mount of the present invention;
fig. 5 is a side view of the mounting bracket of the present invention.
Wherein: 1 bottom plate, 2 casings, 3 mounting brackets, 4PLC controllers, 5 electric putter, 6 driving motor, 7 rotor plates, 8 spouts, 9 slide bars, 10 fastening bolt, 11 installation pieces, 12 fixing bolt, 13 scale marks, 14 range finding boards, 15 four limbs fixing bandage, 16 first magic subsides public face, 17 truck fixing bandage, 18 second magic subsides public face, 19 second magic subsides female face, 20 arc walls, 21 dead lever, 22 sealing plugs, 23 laser rangefinder sensor.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: a mouse dermis injury modeling tool for medical experiments comprises a bottom plate 1 and a shell 2, the shell 2 is fixedly arranged on the outer side surface of the bottom plate 1, the upper surface of the bottom plate 1 is respectively provided with a four-limb fixing mechanism and a trunk fixing mechanism, the outer side surface of the shell 2 is fixedly provided with a mounting rack 3, a PLC controller 4 is arranged on the side surface of the mounting rack 3, the input end of the PLC controller 4 is electrically connected with the output end of an external power supply, the model of the used PLC controller 4 is Siemens S7-200, the lower surface of the mounting rack 3 is fixedly provided with an electric push rod 5, the input end of the electric push rod 5 is electrically connected with the output end of the PLC controller 4, a driving motor 6 is arranged inside the telescopic end of the electric push rod 5, the input end of the driving motor 6 is electrically connected with the output end of the PLC controller 4, the output shaft of the driving motor 6 penetrates through, the surface of the rotating plate 7 is provided with a strip-shaped sliding chute 8, a sliding rod 9 is arranged in the sliding chute 8 in a sliding manner, the outer side surface of the bottom end of the sliding rod 9 is sleeved with an installation block 11, the side surface of the installation block 11 and the outer side surface of the lower part of the sliding rod 9 are both provided with screw holes, the screw holes are connected with fixing bolts 12 in a threaded manner, the lower surface of the installation block 11 is provided with a damage tool, the lower surface of a top plate of the installation frame 3 is provided with a distance measuring device, the mouse dermis damage modeling tool for medical experiments can be conveniently fixed through a four-limb fixing mechanism and a trunk fixing mechanism, the phenomenon that the mouse is disorderly found after being injured and loses control is avoided, the working efficiency is improved, the experimental research is facilitated, meanwhile, the damage tool is installed on the sliding rod 9 through the installation block 11, the damage position can be conveniently, the use flexibility is improved, the operation is simple, and the use is convenient.
Four limbs fixed establishment is including evenly setting up four limbs fixed bandage 15 at 1 upper surface of bottom plate, the inboard surface of expansion end of four limbs fixed bandage 15 has made first magic subsides female face, the upper surface of bottom plate 1 is close to four limbs fixed bandage 15 department and has pasted the first magic subsides male face that corresponds with first magic subsides female face, truck fixed establishment is including setting up two truck fixed bandage 17 at 1 upper surface of bottom plate, second magic subsides female face 19 has been made to the expansion end outside surface of truck fixed bandage 17, and truck fixed bandage 17's upper surface has made the second magic subsides male face 18 that corresponds with second magic subsides female face 19, can conveniently fix the mouse through four limbs fixed establishment and truck fixed establishment, thereby avoid the mouse to run up in disorder after the injury and lose control, work efficiency is improved, be favorable to experimental study.
The upper surface of bottom plate 1 has been seted up arc groove 20 near trunk fixing band 17 activity end department, and the arc groove 20 internal fixation is provided with dead lever 21, and trunk fixing band 17 of being convenient for passes, and is fixed convenient, easy operation.
The distance measuring device comprises a laser distance measuring sensor 23 installed on the lower surface of a top plate of the mounting frame 3, the preferred type of the used laser distance measuring sensor 23 is ZYT-0100, the output end of the laser distance measuring sensor 23 is electrically connected with the input end of the PLC 4, the PLC 4 controls the electric push rod 5, the modes of the driving motor 6 and the laser distance measuring sensor 23 are common methods in the prior art, the telescopic end side surface of the electric push rod 5 is fixedly provided with a distance measuring plate 14 corresponding to the laser distance measuring sensor 23, the distance of the movement of a damage tool can be detected through the laser distance measuring sensor 23 and the distance measuring plate 14, the damage depth is automatically controlled, and the automation degree is improved.
The outer side surface of the slide bar 9 is threadedly connected with a fastening bolt 10 for fixing the slide bar 9 and the position of the damage tool.
The scale marks 13 are uniformly arranged on two sides of the upper surface sliding groove 8 of the rotating plate 7, and the pointer corresponding to the scale marks 13 is arranged on the side surface of the top end of the sliding rod 9, so that the position of the damage tool can be accurately adjusted conveniently, and the adjusting accuracy is improved.
The upper surface of the bottom plate 1 is provided with a water outlet, and a sealing plug 22 is arranged in the water outlet and used for discharging sewage after cleaning.
The PLC controller 4, the electric push rod 5, the driving motor 6, the laser ranging sensor 23, and the like used in the present invention are all common electronic components in the prior art, and the working mode and the circuit structure thereof are all known technologies, and are not described herein.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (8)
1. A mouse dermal injury modeling tool for medical experiments, comprising a bottom plate (1) and a shell (2), characterized in that: the shell (2) is fixedly arranged on the outer side surface of the bottom plate (1), the upper surface of the bottom plate (1) is respectively provided with a four-limb fixing mechanism and a trunk fixing mechanism, the outer side surface of the shell (2) is fixedly provided with a mounting rack (3), a PLC (programmable logic controller) (4) is installed on the side surface of the mounting rack (3), the input end of the PLC (4) is electrically connected with the output end of an external power supply, an electric push rod (5) is fixedly installed on the lower surface of the mounting rack (3), the input end of the electric push rod (5) is electrically connected with the output end of the PLC (4), a driving motor (6) is installed inside the telescopic end of the electric push rod (5), the input end of the driving motor (6) is electrically connected with the output end of the PLC (4), and the output shaft of the driving motor (6) penetrates out of the lower surface of the telescopic end of the electric push, the surface of rotor plate (7) is seted up spout (8) of bar, and it is provided with slide bar (9) to slide in spout (8), and installation piece (11) have been cup jointed on the bottom outside surface of slide bar (9), and the screw has all been seted up on the side surface of installation piece (11) and the lower part outside surface of slide bar (9), and screw female connection has fixing bolt (12), the lower surface of installation piece (11) is provided with the damage instrument, the roof lower surface of mounting bracket (3) is provided with range unit.
2. The mouse dermal injury modeling tool for medical experiments according to claim 1, characterized in that: four limbs fixed establishment has first magic subsides female face including evenly setting up four limbs fixed bandage (15) at bottom plate (1) upper surface, the inboard surface of expansion end of four limbs fixed bandage (15) has been made, the upper surface of bottom plate (1) is close to four limbs fixed bandage (15) department and pastes and has the male face of first magic subsides that corresponds with first magic subsides female face.
3. The mouse dermal injury modeling tool for medical experiments according to claim 1, characterized in that: the trunk fixing mechanism comprises two trunk fixing straps (17) arranged on the upper surface of the base plate (1), a second magic tape female surface (19) is sewn on the outer side surface of the movable end of each trunk fixing strap (17), and a second magic tape male surface (18) corresponding to the second magic tape female surface (19) is sewn on the upper surface of each trunk fixing strap (17).
4. The mouse dermal injury modeling tool for medical experiments according to claim 2, characterized in that: the upper surface of the bottom plate (1) is provided with an arc-shaped groove (20) close to the movable end of the trunk fixing bandage (17), and a fixing rod (21) is fixedly arranged in the arc-shaped groove (20).
5. The mouse dermal injury modeling tool for medical experiments according to claim 1, characterized in that: the range unit is including installing laser rangefinder sensor (23) at mounting bracket (3) roof lower surface, the input of PLC controller (4) is connected to the output electricity of laser rangefinder sensor (23), the flexible distolateral fixed surface of electric putter (5) is provided with range finding board (14) that correspond with laser rangefinder sensor (23).
6. The mouse dermal injury modeling tool for medical experiments according to claim 1, characterized in that: the outer side surface of the sliding rod (9) is in threaded connection with a fastening bolt (10).
7. The mouse dermal injury modeling tool for medical experiments according to claim 1, characterized in that: scale marks (13) are uniformly arranged on two sides of the upper surface sliding groove (8) of the rotating plate (7), and pointers corresponding to the scale marks (13) are arranged on the side surface of the top end of the sliding rod (9).
8. The mouse dermal injury modeling tool for medical experiments according to claim 1, characterized in that: the upper surface of the bottom plate (1) is provided with a water outlet, and a sealing plug (22) is arranged in the water outlet.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202010017950.0A CN111166522A (en) | 2020-01-08 | 2020-01-08 | Mouse dermis injury modeling tool for medical experiment |
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CN202010017950.0A CN111166522A (en) | 2020-01-08 | 2020-01-08 | Mouse dermis injury modeling tool for medical experiment |
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CN202010017950.0A Pending CN111166522A (en) | 2020-01-08 | 2020-01-08 | Mouse dermis injury modeling tool for medical experiment |
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CN209645132U (en) * | 2018-12-12 | 2019-11-19 | 徐州医科大学 | It is a kind of for making the device of animal craniocerebral trauma model |
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2020
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Patent Citations (12)
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CN105616034A (en) * | 2016-03-24 | 2016-06-01 | 周飞虎 | Rat operating platform |
CN107115128A (en) * | 2017-06-16 | 2017-09-01 | 刘晓 | A kind of medical and clinical tumour sampler |
CN107582141A (en) * | 2017-08-23 | 2018-01-16 | 江小兰 | Dorsal nerve of penis Sequestration cutter device under a kind of microscope |
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Application publication date: 20200519 |
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