CN111166522A

CN111166522A - Mouse dermis injury modeling tool for medical experiment

Info

Publication number: CN111166522A
Application number: CN202010017950.0A
Authority: CN
Inventors: 陈珏晓; 荆志远
Original assignee: Jiamusi University
Current assignee: Jiamusi University
Priority date: 2020-01-08
Filing date: 2020-01-08
Publication date: 2020-05-19

Abstract

The invention provides a mouse dermal damage modeling tool for medical experiments, comprising a base plate and a casing, the casing is fixedly arranged on the outer surface of the base plate, and the upper surface of the base plate is respectively provided with a limb fixing mechanism and a trunk fixing mechanism A mounting frame is fixedly arranged on the outer surface of the casing, a PLC controller is installed on the side surface of the mounting frame, and the input end of the PLC controller is electrically connected with the output end of the external power supply. The mouse dermal injury modeling tool used in this medical experiment can easily fix the mouse through the limb fixation mechanism and the trunk fixation mechanism, so as to prevent the mouse from jumping out of control after being injured, improve work efficiency, and facilitate experimental research. At the same time, the damage tool is installed on the sliding rod through the installation block, the damage position can be easily adjusted by adjusting the sliding rod, and the leather of different sizes can be cut by driving the rotation of the driving motor, which improves the flexibility of use, simple operation and convenient use. .

Description

Mouse dermis injury modeling tool for medical experiment

Technical Field

The invention relates to the technical field of medical experiments, in particular to a mouse dermal injury modeling tool for medical experiments.

Background

The skin covers the body surface and sequentially comprises epidermis, dermis and subcutaneous layer from outside to inside. The dermis is differentiated from the mesoderm and is divided into two layers, the papillary layer and the reticular layer, with no distinct boundary between the two layers. The dermis protrudes with numerous papillae and is embedded into the deep surface of the epidermis, which is connected with the superficial fascia through connective tissue fiber bundles. The dermal tissue has the functions of bearing the upper part and the lower part, the upper part bears the epidermis and the lower part opens the subcutaneous tissue, is an important layer of the skin, has structural and functional importance and specificity, and the dermal components can influence the migration, differentiation, adhesion and growth of repair cells and are an important component part for wound repair; by using a part of dermal injury models, the change of each component of the dermis in the wound repair process and the influence of the change on wound healing can be effectively observed.

Most of the existing mouse dermal injury modeling tools for medical experiments can not fix a mouse in the experiment process, the mouse is easy to disorderly jump after being injured and is difficult to control, the tools for damaging the dermis are difficult to adjust, the position of the tools for damaging the dermis can not be flexibly adjusted according to use requirements, the operation is troublesome, and the use is inconvenient.

Disclosure of Invention

The invention aims to solve the problems, and provides a mouse dermis injury modeling tool for medical experiments, which can conveniently fix a mouse through a four-limb fixing mechanism and a trunk fixing mechanism, avoid the mouse from disordering after being injured so as to lose control, improve the working efficiency, and be beneficial to experimental research.

In order to achieve the purpose, the invention adopts the following technical scheme: a mouse dermis damage modeling tool for medical experiments comprises a bottom plate and a shell, wherein the shell is fixedly arranged on the outer side surface of the bottom plate, the upper surface of the bottom plate is respectively provided with a four-limb fixing mechanism and a trunk fixing mechanism, the outer side surface of the shell is fixedly provided with a mounting rack, a PLC (programmable logic controller) is installed on the side surface of the mounting rack, the input end of the PLC is electrically connected with the output end of an external power supply, the lower surface of the mounting rack is fixedly provided with an electric push rod, the input end of the electric push rod is electrically connected with the output end of the PLC, a driving motor is installed inside the telescopic end of the electric push rod, the input end of the driving motor is electrically connected with the output end of the PLC, the output shaft of the driving motor penetrates out of the lower surface of the telescopic end of the electric push rod, slide in the spout and be provided with the slide bar, the bottom outside surface of slide bar has cup jointed the installation piece, and the screw has all been seted up to the side surface of installation piece and the lower part outside surface of slide bar, and screw female connection has fixing bolt, the lower surface of installation piece is provided with the damage instrument, the roof lower surface of mounting bracket is provided with range unit.

As a preferred technical scheme of the present invention, the four-limb fixing mechanism includes four-limb fixing straps uniformly arranged on an upper surface of the base plate, a first hook and loop fastener female surface is sewn on an inner side surface of a movable end of each of the four-limb fixing straps, and a first hook and loop fastener male surface corresponding to the first hook and loop fastener female surface is adhered to a position, close to the four-limb fixing straps, on the upper surface of the base plate.

As a preferred technical scheme of the present invention, the trunk fixing mechanism includes two trunk fixing straps disposed on the upper surface of the base plate, a second hook and loop fastener female surface is sewn on the outer side surface of the movable end of the trunk fixing strap, and a second hook and loop fastener male surface corresponding to the second hook and loop fastener female surface is sewn on the upper surface of the trunk fixing strap.

As a preferred technical scheme of the invention, the upper surface of the bottom plate is provided with an arc-shaped groove close to the movable end of the trunk fixing bandage, and a fixing rod is fixedly arranged in the arc-shaped groove.

According to a preferable technical scheme of the invention, the distance measuring device comprises a laser distance measuring sensor arranged on the lower surface of the top plate of the mounting frame, the output end of the laser distance measuring sensor is electrically connected with the input end of the PLC, and a distance measuring plate corresponding to the laser distance measuring sensor is fixedly arranged on the surface of the telescopic end side of the electric push rod.

As a preferable aspect of the present invention, the outer side surface of the slide bar is threadedly connected with a fastening bolt.

As a preferable technical scheme of the present invention, scale marks are uniformly provided on both sides of the sliding groove on the upper surface of the rotating plate, and a pointer corresponding to the scale marks is provided on the side surface of the top end of the sliding rod.

As a preferable technical scheme of the invention, the upper surface of the bottom plate is provided with a water outlet, and a sealing plug is arranged in the water outlet.

By adopting the technical scheme, the invention has the beneficial effects that: according to the mouse dermis injury modeling tool for medical experiments, disclosed by the invention, a mouse can be conveniently fixed through the four-limb fixing mechanism and the trunk fixing mechanism, the mouse is prevented from disorganizing after being injured and losing control, the working efficiency is improved, experimental research is facilitated, meanwhile, the injury tool is arranged on the sliding rod through the mounting block, the injury position can be conveniently adjusted through adjusting the sliding rod, dermis with different sizes can be cut out through driving the rotation of the driving motor, the use flexibility is improved, the operation is simple, and the use is convenient.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of the structure of FIG. 1 at point A according to the present invention;

FIG. 3 is a schematic structural diagram of the base plate of the present invention;

FIG. 4 is a schematic structural view of a mount of the present invention;

fig. 5 is a side view of the mounting bracket of the present invention.

Wherein: 1 bottom plate, 2 casings, 3 mounting brackets, 4PLC controllers, 5 electric putter, 6 driving motor, 7 rotor plates, 8 spouts, 9 slide bars, 10 fastening bolt, 11 installation pieces, 12 fixing bolt, 13 scale marks, 14 range finding boards, 15 four limbs fixing bandage, 16 first magic subsides public face, 17 truck fixing bandage, 18 second magic subsides public face, 19 second magic subsides female face, 20 arc walls, 21 dead lever, 22 sealing plugs, 23 laser rangefinder sensor.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-5, the present invention provides a technical solution: a mouse dermis injury modeling tool for medical experiments comprises a bottom plate 1 and a shell 2, the shell 2 is fixedly arranged on the outer side surface of the bottom plate 1, the upper surface of the bottom plate 1 is respectively provided with a four-limb fixing mechanism and a trunk fixing mechanism, the outer side surface of the shell 2 is fixedly provided with a mounting rack 3, a PLC controller 4 is arranged on the side surface of the mounting rack 3, the input end of the PLC controller 4 is electrically connected with the output end of an external power supply, the model of the used PLC controller 4 is Siemens S7-200, the lower surface of the mounting rack 3 is fixedly provided with an electric push rod 5, the input end of the electric push rod 5 is electrically connected with the output end of the PLC controller 4, a driving motor 6 is arranged inside the telescopic end of the electric push rod 5, the input end of the driving motor 6 is electrically connected with the output end of the PLC controller 4, the output shaft of the driving motor 6 penetrates through, the surface of the rotating plate 7 is provided with a strip-shaped sliding chute 8, a sliding rod 9 is arranged in the sliding chute 8 in a sliding manner, the outer side surface of the bottom end of the sliding rod 9 is sleeved with an installation block 11, the side surface of the installation block 11 and the outer side surface of the lower part of the sliding rod 9 are both provided with screw holes, the screw holes are connected with fixing bolts 12 in a threaded manner, the lower surface of the installation block 11 is provided with a damage tool, the lower surface of a top plate of the installation frame 3 is provided with a distance measuring device, the mouse dermis damage modeling tool for medical experiments can be conveniently fixed through a four-limb fixing mechanism and a trunk fixing mechanism, the phenomenon that the mouse is disorderly found after being injured and loses control is avoided, the working efficiency is improved, the experimental research is facilitated, meanwhile, the damage tool is installed on the sliding rod 9 through the installation block 11, the damage position can be conveniently, the use flexibility is improved, the operation is simple, and the use is convenient.

Four limbs fixed establishment is including evenly setting up four limbs fixed bandage 15 at 1 upper surface of bottom plate, the inboard surface of expansion end of four limbs fixed bandage 15 has made first magic subsides female face, the upper surface of bottom plate 1 is close to four limbs fixed bandage 15 department and has pasted the first magic subsides male face that corresponds with first magic subsides female face, truck fixed establishment is including setting up two truck fixed bandage 17 at 1 upper surface of bottom plate, second magic subsides female face 19 has been made to the expansion end outside surface of truck fixed bandage 17, and truck fixed bandage 17's upper surface has made the second magic subsides male face 18 that corresponds with second magic subsides female face 19, can conveniently fix the mouse through four limbs fixed establishment and truck fixed establishment, thereby avoid the mouse to run up in disorder after the injury and lose control, work efficiency is improved, be favorable to experimental study.

The upper surface of bottom plate 1 has been seted up arc groove 20 near trunk fixing band 17 activity end department, and the arc groove 20 internal fixation is provided with dead lever 21, and trunk fixing band 17 of being convenient for passes, and is fixed convenient, easy operation.

The distance measuring device comprises a laser distance measuring sensor 23 installed on the lower surface of a top plate of the mounting frame 3, the preferred type of the used laser distance measuring sensor 23 is ZYT-0100, the output end of the laser distance measuring sensor 23 is electrically connected with the input end of the PLC 4, the PLC 4 controls the electric push rod 5, the modes of the driving motor 6 and the laser distance measuring sensor 23 are common methods in the prior art, the telescopic end side surface of the electric push rod 5 is fixedly provided with a distance measuring plate 14 corresponding to the laser distance measuring sensor 23, the distance of the movement of a damage tool can be detected through the laser distance measuring sensor 23 and the distance measuring plate 14, the damage depth is automatically controlled, and the automation degree is improved.

The outer side surface of the slide bar 9 is threadedly connected with a fastening bolt 10 for fixing the slide bar 9 and the position of the damage tool.

The scale marks 13 are uniformly arranged on two sides of the upper surface sliding groove 8 of the rotating plate 7, and the pointer corresponding to the scale marks 13 is arranged on the side surface of the top end of the sliding rod 9, so that the position of the damage tool can be accurately adjusted conveniently, and the adjusting accuracy is improved.

The upper surface of the bottom plate 1 is provided with a water outlet, and a sealing plug 22 is arranged in the water outlet and used for discharging sewage after cleaning.

The PLC controller 4, the electric push rod 5, the driving motor 6, the laser ranging sensor 23, and the like used in the present invention are all common electronic components in the prior art, and the working mode and the circuit structure thereof are all known technologies, and are not described herein.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. A mouse dermis damage modeling tool for medical experiments, comprising a base plate (1) and a casing (2), wherein the casing (2) is fixedly arranged on the outer surface of the base plate (1), The upper surface of the base plate (1) is respectively provided with a limb fixing mechanism and a trunk fixing mechanism, a mounting bracket (3) is fixedly arranged on the outer surface of the casing (2), and a PLC is mounted on the side surface of the mounting bracket (3). A controller (4), the input end of the PLC controller (4) is electrically connected with the output end of the external power supply, the lower surface of the mounting frame (3) is fixedly installed with an electric push rod (5), the electric The input end of the push rod (5) is electrically connected with the output end of the PLC controller (4). A drive motor (6) is installed inside the telescopic end of the electric push rod (5). The input end of the drive motor (6) The end is electrically connected to the output end of the PLC controller (4). The output shaft of the drive motor (6) penetrates the lower surface of the telescopic end of the electric push rod (5) and is fixedly connected to the rotating plate (7). The rotating plate (7) ) is provided with a strip-shaped chute (8), a sliding rod (9) is slidably arranged in the chute (8), and a mounting block (11) is sleeved on the outer surface of the bottom end of the sliding rod (9). The side surface of (11) and the lower outer surface of the sliding rod (9) are provided with screw holes, and the screw holes are threadedly connected with fixing bolts (12), and the lower surface of the mounting block (11) is provided with a damage tool, so A distance measuring device is arranged on the lower surface of the top plate of the mounting frame (3).

2. The mouse dermal damage modeling tool for medical experiments according to claim 1, wherein the limb fixing mechanism comprises four limb fixing straps (15) evenly arranged on the upper surface of the base plate (1) , the inner surface of the movable end of the limb fixing strap (15) is sewn with a first Velcro mother surface, and the upper surface of the bottom plate (1) close to the limb fixing strap (15) is pasted with the first Velcro mother surface Corresponding to the first Velcro male surface.

3. The mouse dermis injury modeling tool for medical experiments according to claim 1, wherein the trunk fixing mechanism comprises two trunk fixing straps (17) arranged on the upper surface of the base plate (1), A second female Velcro surface (19) is sewn on the outer surface of the movable end of the torso fixing strap (17), and a second Velcro mother surface (19) is sewn on the upper surface of the torso fixing strap (17) of the second Velcro male side (18).

4. The mouse dermal injury modeling tool for medical experiments according to claim 2, wherein the upper surface of the bottom plate (1) is provided with an arc-shaped groove near the active end of the trunk fixing strap (17). (20), a fixing rod (21) is fixedly arranged in the arc-shaped groove (20).

5. The mouse dermal damage modeling tool for medical experiments according to claim 1, wherein the distance measuring device comprises a laser distance measuring sensor (23) installed on the lower surface of the top plate of the mounting frame (3), The output end of the laser distance measuring sensor (23) is electrically connected to the input end of the PLC controller (4), and the telescopic end side surface of the electric push rod (5) is fixedly provided with a corresponding laser distance measuring sensor (23). Rangefinder board (14).

6 . The mouse dermis injury modeling tool for medical experiments according to claim 1 , wherein the outer surface of the sliding rod ( 9 ) is threadedly connected with a fastening bolt ( 10 ). 7 .

7. The mouse dermal injury modeling tool for medical experiments according to claim 1, wherein the upper surface of the rotating plate (7) is evenly provided with scale lines (13) on both sides of the chute (8) , the top end side surface of the sliding rod (9) is provided with a pointer corresponding to the scale line (13).

8 . The mouse dermal damage modeling tool for medical experiments according to claim 1 , wherein a drainage port is provided on the upper surface of the bottom plate ( 1 ), and a sealing plug ( 22 ) is arranged in the drainage port. 9 .