CN111166292B - Two-dimensional focusing magnetic induction excitation array and method for lamellar sample magnetoacoustic imaging - Google Patents
Two-dimensional focusing magnetic induction excitation array and method for lamellar sample magnetoacoustic imaging Download PDFInfo
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- CN111166292B CN111166292B CN202010028013.5A CN202010028013A CN111166292B CN 111166292 B CN111166292 B CN 111166292B CN 202010028013 A CN202010028013 A CN 202010028013A CN 111166292 B CN111166292 B CN 111166292B
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Abstract
The utility model provides a two-dimentional focus magnetic induction excitation array for stratiform sample magnetic acoustic imaging, includes the excitation flat board and sets up the dull and stereotyped that gives sound insulation below the excitation flat board, the excitation flat board on be equipped with n coils, the coil is arranged in applying the magnetic induction excitation to the position that corresponds with each coil in waiting to image the sample that is located the dull and stereotyped that gives sound insulation, the dull and stereotyped noise signal that is used for keeping apart the dull and stereotyped coil of excitation produces treats the interference of image the sample, every the coil all pass through the wire that is connected and link to each other with outside excitation source. The two-dimensional focusing magnetic induction excitation array and the method for the magnetoacoustic imaging of the layered sample can obviously improve the detection precision of the tissue surface of the magnetoacoustic imaging and the in-vivo measurement of the layered sample, and obtain the high-resolution tissue electrical characteristic functional imaging.
Description
Technical Field
The present invention relates to a magnetoacoustic imaging apparatus. In particular to a two-dimensional focusing magnetic induction excitation array and a method for lamellar sample magnetoacoustic imaging.
Background
The novel magnetic acoustic coupling imaging method represents an important research value in the aspect of monitoring the function of the tissue electrical characteristics. The method applies orthogonal electromagnetic excitation to the tissue, converts electrical characteristic parameters of the tissue into acoustic vibration, extracts the electrical characteristics of the tissue by using an acoustic detection method, and realizes high-resolution electrical characteristic functional imaging.
At present, the magnetoacoustic imaging research generally adopts a measurement mode combining single pulse excitation and tomography scanning, the detection precision of the mode is low, and signals are submerged in noise and have obvious influence on detection imaging. Therefore, the detection precision of the in-vivo measurement of the sample, particularly the layered sample, can be effectively improved by adopting the excitation mode of combining continuous sine excitation and two-dimensional focusing magnetic induction. In a word, the design of the two-dimensional focusing magnetic induction excitation array has important significance.
Disclosure of Invention
The invention aims to solve the technical problem of providing a two-dimensional focusing magnetic induction excitation array and a method for lamellar sample magnetoacoustic imaging, which can effectively improve the detection precision of lamellar sample in-vivo measurement.
The technical scheme adopted by the invention is as follows: the utility model provides a two-dimentional focus magnetic induction excitation array for stratiform sample magnetic acoustic imaging, includes the excitation flat board and sets up the dull and stereotyped that gives sound insulation below the excitation flat board, the excitation flat board on be equipped with n coils, the coil is arranged in applying the magnetic induction excitation to the position that corresponds with each coil in waiting to image the sample that is located the dull and stereotyped that gives sound insulation, the dull and stereotyped noise signal that is used for keeping apart the dull and stereotyped coil of excitation produces treats the interference of image the sample, every the coil all pass through the wire that is connected and link to each other with outside excitation source.
The excitation flat plate and the sound insulation flat plate are in fit connection.
The coil is fixed on the excitation panel through hot melt adhesive or printed on the excitation panel through flexible printed circuit board technology.
The n is 10-10000.
The diameter of each coil on the excitation flat plate is c, the distance between the centers of two adjacent coils is a, and a is more than c.
The c is 0.5-2 mm, and the wire diameter of the coil is 0.1-0.3 mm.
The a is 1 mm-15 mm.
The excitation flat plate is a flexible insulation plate capable of being bent, the thickness of the excitation flat plate is 0.5 mm-2 mm, the sound insulation flat plate is made of sound insulation sponge, and the thickness of the sound insulation flat plate is 0.5 mm-2 mm.
An excitation method for a two-dimensional focused magnetic induction excitation array for magnetoacoustic imaging of a layered sample, comprising:
1) horizontally placing a sample to be imaged below a two-dimensional focusing magnetic induction excitation array formed by an excitation flat plate and a sound insulation flat plate;
2) arranging a free field microphone for acquiring magneto-acoustic signals of a sample to be imaged below the sample to be imaged, wherein the output end of the free field microphone is connected with an external signal acquisition device;
3) and (2) introducing a sinusoidal current excitation signal with the amplitude I and the frequency f to the coil sequentially through the lead wire on each coil, acquiring magnetoacoustic signals of the part, corresponding to the coil, on a sample to be imaged through the free field microphone, sending the magnetoacoustic signals to an external signal acquisition device, and when the sinusoidal current excitation signal is introduced to the coil, exciting the rest of coils on the flat plate to be in a non-conduction state.
The amplitude I in the step 3) is 0.1A-10A, and the frequency f is 1 kHz-10 MHz.
The two-dimensional focusing magnetic induction excitation array and the method for the magnetoacoustic imaging of the layered sample can obviously improve the detection precision of the tissue surface of the magnetoacoustic imaging and the in-vivo measurement of the layered sample, and obtain the high-resolution tissue electrical characteristic functional imaging.
Drawings
FIG. 1 is a schematic diagram of an exploded structure of a two-dimensional focused magnetic induction excitation array for magnetoacoustic imaging of a layered sample according to the present invention;
FIG. 2 is a schematic diagram of the arrangement of the magnetic induction excitation array coil on the excitation plate in the present invention;
FIG. 3 is a schematic diagram of the use state of the two-dimensional focused magnetic induction excitation array for lamellar sample magnetoacoustic imaging according to the present invention.
In the drawings
1: excitation plate 2: sound insulation flat plate
3: sample to be imaged 4: conducting wire
5: and (6) a lead wire: free field microphone
Detailed Description
The two-dimensional focused magnetic induction excitation array and the method for laminated sample magnetoacoustic imaging according to the present invention are described in detail below with reference to the embodiments and the accompanying drawings.
As shown in fig. 1 and fig. 2, the two-dimensional focusing magnetic induction excitation array for lamellar sample magnetoacoustic imaging according to the present invention includes an excitation plate 1 and a sound insulation plate 2 disposed below the excitation plate 1, wherein the excitation plate 1 and the sound insulation plate 2 are in bonded connection. The excitation panel 1 is provided with n × n coils 4, the coils 4 are fixed on the excitation panel 1 through hot melt adhesive, or printed on the excitation panel 1 through a flexible printed circuit board technology, where n is 10-10000, and n is 10 in the embodiment of the present invention. The coil 4 is used for applying magnetic induction excitation to the part corresponding to each coil in the sample 3 to be imaged positioned below the sound insulation flat plate 2, the sound insulation flat plate 2 is used for isolating the interference of noise signals generated by the coils on the excitation flat plate 1 on the sample 3 to be imaged, and each coil 4 is connected with an external excitation source through a lead 5 connected with the coil.
The diameter of each coil 4 on the excitation flat plate 1 is c, the distance between the centers of two adjacent coils 4 is a, and a is more than c. Wherein c is 0.5-2 mm, and the wire diameter of the coil 4 is 0.1-0.3 mm. The a is 1 mm-15 mm.
In the embodiment of the invention, the a is 1mm, the c is 0.5mm, and the wire diameter of the coil 4 is 0.1 mm.
The excitation flat plate 1 is a flexible insulation plate capable of being bent, such as a rubber plate or a silica gel plate, the thickness of the excitation flat plate is 0.5 mm-2 mm, the sound insulation flat plate 2 is made of sound insulation sponge, and the thickness of the sound insulation flat plate is 0.5 mm-2 mm. In the embodiment of the invention, the thicknesses of the excitation flat plate 1 and the sound insulation flat plate 2 are both 0.5 mm.
As shown in fig. 3, the excitation method of the two-dimensional focused magnetic induction excitation array for lamellar sample magnetoacoustic imaging according to the present invention comprises the following steps:
1) horizontally placing a sample 3 to be imaged below a two-dimensional focusing magnetic induction excitation array formed by an excitation flat plate 1 and a sound insulation flat plate 2;
2) arranging a free field microphone 6 for acquiring magneto-acoustic signals of a sample 3 to be imaged below the sample 3 to be imaged, wherein the output end of the free field microphone 6 is connected with an external signal acquisition device;
3) the coil 4 is sequentially fed with sinusoidal current excitation signals with amplitude I and frequency f through the lead 5 on each coil 4, magnetoacoustic signals of the part, corresponding to the coil 4, on the sample 3 to be imaged are collected through the free field microphone 6, and are sent to an external signal collecting device, wherein the amplitude I is 0.1-10A, the frequency f is 1 kHz-10 MHz, and the amplitude I is 0.1A and the frequency f is 1 kHz. In the present invention, when a sinusoidal current excitation signal is applied to one of the coils 4, the remaining coils 4 on the excitation plate 1 are all in a non-conductive state. Take the example of selecting n as 10:
the coil in row 1 and column 1 is energized with a sinusoidal current of amplitude I and frequency f, and the remaining coils are off.
The coil in row 1 and column 2 is energized with a sinusoidal current of amplitude I, frequency f, and the remaining coils are de-energized.
……
The coil in row 1 and column 10 is energized with a sinusoidal current of amplitude I and frequency f, and the remaining coils are off.
The coil in row 2 and column 1 is energized with a sinusoidal current of amplitude I and frequency f, and the remaining coils are off.
The coil in row 2 and column 2 is energized with a sinusoidal current of amplitude I and frequency f, and the remaining coils are off.
……
The coil in row 2 and column 10 is energized with a sinusoidal current of amplitude I and frequency f, and the remaining coils are off.
……
The 10 th row, column 1 coil is energized with a sinusoidal current of amplitude I, frequency f, and the remaining coils are off.
The 10 th row, 2 nd column coil is energized with a sinusoidal current of amplitude I, frequency f, and the remaining coils are off.
……
The 10 th row and 10 th column coils are energized with a sinusoidal current of amplitude I and frequency f, and the remaining coils are off.
Claims (10)
1. A two-dimensional focusing magnetic induction excitation array for lamellar sample magnetoacoustic imaging is characterized by comprising an excitation flat plate (1) and a sound insulation flat plate (2) arranged below the excitation flat plate (1), the excitation flat plate (1) is provided with n multiplied by n coils (4), the coils (4) are used for applying magnetic induction excitation to the parts corresponding to the coils in the sample (3) to be imaged, which is positioned below the sound insulation flat plate (2), the sound insulation flat plate (2) is used for isolating noise signals generated by the coils on the excitation flat plate (1) from interfering with a sample (3) to be imaged, each coil (4) is connected with an external excitation source through a lead (5) connected with the coil, when a continuous sinusoidal current excitation signal is applied to one coil (4) on the excitation panel (1), the rest coils (4) on the excitation flat plate (1) are in a non-conducting state.
2. The two-dimensional focused magnetic induction excitation array for the magnetoacoustic imaging of the layered sample according to claim 1, wherein the excitation plate (1) and the sound insulation plate (2) are in a fit connection.
3. Two-dimensional focused magnetic induction excitation array for magnetoacoustic imaging of layered samples according to claim 1, characterized in that the coil (4) is fixed on the excitation plate (1) by means of hot melt adhesive or printed on the excitation plate (1) by means of flexible printed circuit board technology.
4. The two-dimensional focused magnetic induction excitation array for layered sample magnetoacoustic imaging according to claim 1, wherein n = 10-10000.
5. The two-dimensional focused magnetic induction excitation array for lamellar sample magnetoacoustic imaging according to claim 1, characterized in that the diameter of each coil (4) on the excitation plate (1) is c, the distance between the centers of two adjacent coils (4) is a, and a > c.
6. The two-dimensional focused magnetic induction excitation array for lamellar sample magnetoacoustic imaging according to claim 5, characterized in that c = 0.5-2 mm and the wire diameter of the coil (4) is 0.1-0.3 mm.
7. The two-dimensional focused magnetic induction excitation array for layered sample magnetoacoustic imaging of claim 5, wherein a =1 mm-15 mm.
8. The two-dimensional focused magnetic induction excitation array for the magnetoacoustic imaging of the layered sample according to claim 1, wherein the excitation plate (1) is a flexible insulation plate capable of bending and has a thickness of 0.5mm to 2mm, and the sound insulation plate (2) is made of sound insulation sponge and has a thickness of 0.5mm to 2 mm.
9. A method of excitation of a two-dimensional focused magnetic induction excitation array for magnetoacoustic imaging of a layered sample according to claim 1, comprising:
1) horizontally placing a sample (3) to be imaged below a two-dimensional focusing magnetic induction excitation array formed by an excitation flat plate (1) and a sound insulation flat plate (2);
2) arranging a free field microphone (6) for acquiring magneto-acoustic signals of a sample (3) to be imaged below the sample (3) to be imaged, wherein the output end of the free field microphone (6) is connected with an external signal acquisition device;
3) and continuous sinusoidal current excitation signals with the amplitude of I and the frequency of f are sequentially introduced into the corresponding coil (4) through the lead (5) on each coil (4), magnetoacoustic signals of the part, corresponding to the coil (4) which is being electrified, on the sample (3) to be imaged are collected through the free field microphone (6), the magnetoacoustic signals are sent to an external signal collection device, and when the continuous sinusoidal current excitation signals are introduced into one coil (4) on the excitation panel (1), the rest coils (4) on the excitation panel (1) are in a non-conduction state.
10. The excitation method of the two-dimensional focused magnetic induction excitation array for the magnetoacoustic imaging of the layered sample according to claim 9, wherein the amplitude I in the step 3) is 0.1A to 10A, and the frequency f is 1kHz to 10 MHz.
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Citations (4)
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JPH01208816A (en) * | 1988-02-17 | 1989-08-22 | Fuji Electric Co Ltd | Magnet for nuclear magnetic resonance diagnostic apparatus |
JPH06242786A (en) * | 1991-03-26 | 1994-09-02 | Matsushita Electric Works Ltd | Method and device for sound insulation |
CN104013388A (en) * | 2014-06-13 | 2014-09-03 | 中国医学科学院生物医学工程研究所 | Magneto-acoustic coupling imaging excitation and detection method and device based on low-frequency continuous waves |
CN104688224A (en) * | 2015-03-31 | 2015-06-10 | 中国医学科学院生物医学工程研究所 | Magneto-acoustic coupling imaging reconstruction method applied to acoustic uneven media |
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2020
- 2020-01-10 CN CN202010028013.5A patent/CN111166292B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH01208816A (en) * | 1988-02-17 | 1989-08-22 | Fuji Electric Co Ltd | Magnet for nuclear magnetic resonance diagnostic apparatus |
JPH06242786A (en) * | 1991-03-26 | 1994-09-02 | Matsushita Electric Works Ltd | Method and device for sound insulation |
CN104013388A (en) * | 2014-06-13 | 2014-09-03 | 中国医学科学院生物医学工程研究所 | Magneto-acoustic coupling imaging excitation and detection method and device based on low-frequency continuous waves |
CN104688224A (en) * | 2015-03-31 | 2015-06-10 | 中国医学科学院生物医学工程研究所 | Magneto-acoustic coupling imaging reconstruction method applied to acoustic uneven media |
Non-Patent Citations (2)
Title |
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注入电流式磁声成像的电导率模型构建和实验研究;张顺起等;《中国生物医学工程学报》;20111220(第06期);全文 * |
生物感应式磁声成像的研究现状;马真等;《中国生物医学工程学报》;20161220(第06期);全文 * |
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