CN111152954A - Aseptic filling method for processing traditional Chinese medicine decoction pieces - Google Patents
Aseptic filling method for processing traditional Chinese medicine decoction pieces Download PDFInfo
- Publication number
- CN111152954A CN111152954A CN202010028449.4A CN202010028449A CN111152954A CN 111152954 A CN111152954 A CN 111152954A CN 202010028449 A CN202010028449 A CN 202010028449A CN 111152954 A CN111152954 A CN 111152954A
- Authority
- CN
- China
- Prior art keywords
- ampoule bottle
- ampoule
- cleaning
- chinese medicine
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/26—Methods or devices for controlling the quantity of the material fed or filled
- B65B3/28—Methods or devices for controlling the quantity of the material fed or filled by weighing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
- B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
- B65B55/10—Sterilising wrappers or receptacles prior to, or during, packaging by liquids or gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/24—Cleaning of, or removing dust from, containers, wrappers, or packaging ; Preventing of fouling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B57/00—Automatic control, checking, warning, or safety devices
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B21/00—Arrangements or duct systems, e.g. in combination with pallet boxes, for supplying and controlling air or gases for drying solid materials or objects
Abstract
The invention discloses an aseptic filling method for processing traditional Chinese medicine decoction pieces, which specifically comprises the following steps: s1: firstly, putting the ampoule bottle into a cleaning machine for cleaning, and driving an inner cylinder in the cleaning machine to rotate by a built-in motor in the cleaning machine in the cleaning process so as to accelerate the cleaning efficiency of the ampoule bottle; s2: placing the cleaned ampoule bottles in a plastic containing box, placing the ampoule bottles with the bottle openings facing upwards and the bottle bottoms facing downwards, and then placing the plastic containing box filled with the ampoule bottles in a drying machine for drying. According to the invention, multiple disinfection processes are carried out in the ampoule bottle before filling, so that the disinfection effect of the ampoule bottle body and the ampoule bottle can be greatly improved, the breeding of bacteria and harmful germs is reduced, the weight of the traditional Chinese medicine decoction pieces in the filling process can be detected, the raw material waste phenomenon caused by more filling of the traditional Chinese medicine decoction pieces is avoided, and the corresponding filling requirements are met.
Description
Technical Field
The invention relates to the technical field of processing and filling of traditional Chinese medicine decoction pieces, in particular to an aseptic filling method for processing the traditional Chinese medicine decoction pieces.
Background
The traditional Chinese medicine decoction pieces are prepared by processing traditional Chinese medicines according to a traditional Chinese medicine theory and a traditional Chinese medicine preparation method, can be directly used for traditional Chinese medicine clinical treatment, comprise part of traditional Chinese medicine slices processed through a production place, original-shaped medicinal material decoction pieces and decoction pieces subjected to cutting and processing, are regarded as traditional Chinese medicines in the first two categories of management, are only understood as decoction pieces in a formula and a preparation according to the traditional Chinese medicine theory, and the traditional Chinese medicine decoction pieces are required to be filled in finished products in the processing process so as to prolong the quality guarantee period of the traditional Chinese medicine decoction pieces.
However, the traditional filling method has many disadvantages, such as difficulty in guaranteeing sterility in the filling process, particularly the problem that a large amount of bacteria exist in an ampoule bottle, the traditional Chinese medicine decoction pieces are easy to deteriorate after being filled, and the like, and meanwhile, the filling weight of the traditional Chinese medicine decoction pieces is difficult to correspondingly detect, and the problem that the filling does not reach the standard easily exists. Therefore, the technical personnel in the field provide an aseptic filling method for processing Chinese herbal pieces to solve the problems in the background technology.
Disclosure of Invention
The invention aims to provide an aseptic filling method for processing traditional Chinese medicine decoction pieces, which aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
an aseptic filling method for processing traditional Chinese medicine decoction pieces specifically comprises the following steps:
s1: firstly, putting the ampoule bottle into a cleaning machine for cleaning, and driving an inner cylinder in the cleaning machine to rotate by a built-in motor in the cleaning machine in the cleaning process so as to accelerate the cleaning efficiency of the ampoule bottle;
s2: placing the cleaned ampoule bottle in a plastic containing box, wherein the bottle mouth of the ampoule bottle is upward and the bottle bottom of the ampoule bottle is downward in the placing process, then placing the plastic containing box containing the ampoule bottle in a drying machine for drying, and blowing air into a drying bin from top to bottom in the drying process so as to accelerate the drying efficiency of the ampoule bottle body and the ampoule bottle;
s3: placing the dried ampoule bottle in a placing groove formed in a production line, filling traditional Chinese medicine decoction pieces into the ampoule bottle by a filling machine positioned above the placing groove, then carrying out capping treatment on the bottleneck of the ampoule bottle, wherein the ampoule bottle is integrally weighed before being placed in the placing groove, the traditional Chinese medicine decoction pieces are secondarily weighed after being filled, and subtracting the values of the secondary weighing to obtain the weight value of the filled traditional Chinese medicine decoction pieces so as to judge whether the filling weight of the traditional Chinese medicine decoction pieces reaches the standard or not;
s4: the method comprises the following steps of performing sealing detection on the bottleneck of the canned finished ampoule bottle, wherein the detection comprises the following specific steps: taking off five ampoules at intervals, then placing the ampoules into a bottle cap sealing tester for sealing detection, and finally placing unqualified products into S3 for re-capping;
s5: and (3) packaging the filled finished ampoule bottle in a refrigerated cabinet for later use, wherein the temperature in the refrigerated cabinet is controlled to be between-3 and-6 ℃.
As a still further scheme of the invention: the qualified standard of the weighed traditional Chinese medicine decoction pieces in the S3 is less than or equal to 50g, an unqualified product label is attached to the corresponding ampoule bottle when the weight of the traditional Chinese medicine decoction pieces is more than 50g, the traditional Chinese medicine decoction pieces in the ampoule bottle are poured out, the ampoule bottle is put into the cleaning machine in the S1 again for cleaning and subsequent use, and the traditional Chinese medicine decoction pieces are crushed and prepared again to meet the corresponding filling requirement.
As a still further scheme of the invention: before the ampoule bottle is put into the cleaning machine for cleaning in the S1, a disinfectant is poured into the cleaning machine, so that the disinfection effect of the ampoule bottle body and the ampoule bottle interior is improved.
As a still further scheme of the invention: and the cleaning machine in the S1 is an ultrasonic cleaning machine, wherein the cleaning time is 5min, and the cleaning liquid is heated in the cleaning process, wherein the heating temperature is higher than 95 ℃.
As a still further scheme of the invention: and after the S1 is cleaned by the disinfectant, the water is cleaned again by clear water, and the water temperature in the two cleaning processes is the same.
As a still further scheme of the invention: and the drying temperature of the dryer in the S2 is controlled to be 50-80 ℃, and the drying time is 1-3 min.
Compared with the prior art, the invention has the beneficial effects that: according to the invention, multiple disinfection processes are carried out in the ampoule bottle before filling, so that the disinfection effect of the ampoule bottle body and the ampoule bottle can be greatly improved, the breeding of bacteria and harmful germs is reduced, the weight of the traditional Chinese medicine decoction pieces in the filling process can be detected, the raw material waste phenomenon caused by more filling of the traditional Chinese medicine decoction pieces is avoided, and the corresponding filling requirements are met.
Detailed Description
In embodiment 1 of the present invention, an aseptic filling method for processing herbal pieces-of-chinese medicine specifically includes the following steps:
s1: firstly, putting the ampoule bottle into a cleaning machine for cleaning, and driving an inner cylinder in the cleaning machine to rotate by a built-in motor in the cleaning machine in the cleaning process so as to accelerate the cleaning efficiency of the ampoule bottle;
s2: placing the cleaned ampoule bottle in a plastic containing box, wherein the bottle mouth of the ampoule bottle is upward and the bottle bottom of the ampoule bottle is downward in the placing process, then placing the plastic containing box containing the ampoule bottle in a drying machine for drying, and blowing air into a drying bin from top to bottom in the drying process so as to accelerate the drying efficiency of the ampoule bottle body and the ampoule bottle;
s3: placing the dried ampoule bottle in a placing groove formed in a production line, filling traditional Chinese medicine decoction pieces into the ampoule bottle by a filling machine positioned above the placing groove, then carrying out capping treatment on the bottleneck of the ampoule bottle, wherein the ampoule bottle is integrally weighed before being placed in the placing groove, the traditional Chinese medicine decoction pieces are secondarily weighed after being filled, and subtracting the values of the secondary weighing to obtain the weight value of the filled traditional Chinese medicine decoction pieces so as to judge whether the filling weight of the traditional Chinese medicine decoction pieces reaches the standard or not;
s4: the method comprises the following steps of performing sealing detection on the bottleneck of the canned finished ampoule bottle, wherein the detection comprises the following specific steps: taking off five ampoules at intervals, then placing the ampoules into a bottle cap sealing tester for sealing detection, and finally placing unqualified products into S3 for re-capping;
s5: and (3) packaging the filled finished ampoule bottle in a refrigerated cabinet for later use, wherein the temperature in the refrigerated cabinet is controlled to be between-3 and-6 ℃.
Preferably: the qualified standard of the weighed traditional Chinese medicine decoction pieces in the S3 is less than or equal to 50g, an unqualified product label is attached to the corresponding ampoule bottle when the weight of the traditional Chinese medicine decoction pieces is more than 50g, the traditional Chinese medicine decoction pieces in the ampoule bottle are poured out, the ampoule bottle is put into the cleaning machine in the S1 again for cleaning and subsequent use, and the traditional Chinese medicine decoction pieces are crushed and prepared again to meet the corresponding filling requirement.
Preferably: s1, before the ampoule bottle is put into a cleaning machine for cleaning, a disinfectant is poured into the cleaning machine to increase the disinfection effect of the ampoule bottle body and the ampoule bottle, wherein the disinfectant is prepared by the following steps: 1. taking 15% of deionized water, 30% of ethanol and 40% of hydrogen peroxide according to mass percentage, sequentially pouring the raw materials into a transparent glass container with the volume of 4L, and stirring for 5min through a stirring shaft to fully mix the raw materials, the ethanol and the hydrogen peroxide; 2. placing the mixed solution in an environment with the temperature of 50 ℃ for standing for 2 hours; 3. and (3) fully stirring the mixed solution of 6% of glyceryl monostearate by mass for 6min by using a stirring shaft, and standing for 1.5h in an environment with the temperature of 50 ℃ again to fully mix the mixed solution to obtain the finished disinfectant.
Preferably: the cleaning machine in the S1 is an ultrasonic cleaning machine, wherein the cleaning time is 5min, and the cleaning liquid is heated in the cleaning process, wherein the heating temperature is more than 95 ℃.
Preferably: s1, after being cleaned by the disinfectant, the water is cleaned again by clean water, and the water temperature in the two cleaning processes is the same.
Preferably: and the drying temperature of the dryer in the S2 is controlled to be 50-80 ℃, and the drying time is 1-3 min.
In embodiment 2 of the present invention, an aseptic filling method for processing herbal pieces-of-chinese medicine specifically includes the following steps:
s1: firstly, putting the ampoule bottle into a cleaning machine for cleaning, and driving an inner cylinder in the cleaning machine to rotate by a built-in motor in the cleaning machine in the cleaning process so as to accelerate the cleaning efficiency of the ampoule bottle;
s2: placing the cleaned ampoule bottle in a plastic containing box, wherein the bottle mouth of the ampoule bottle is upward and the bottle bottom of the ampoule bottle is downward in the placing process, then placing the plastic containing box containing the ampoule bottle in a drying machine for drying, and blowing air into a drying bin from top to bottom in the drying process so as to accelerate the drying efficiency of the ampoule bottle body and the ampoule bottle;
s3: placing the dried ampoule bottle in a placing groove formed in a production line, filling traditional Chinese medicine decoction pieces into the ampoule bottle by a filling machine positioned above the placing groove, then carrying out capping treatment on the bottleneck of the ampoule bottle, wherein the ampoule bottle is integrally weighed before being placed in the placing groove, the traditional Chinese medicine decoction pieces are secondarily weighed after being filled, and subtracting the values of the secondary weighing to obtain the weight value of the filled traditional Chinese medicine decoction pieces so as to judge whether the filling weight of the traditional Chinese medicine decoction pieces reaches the standard or not;
s4: the method comprises the following steps of performing sealing detection on the bottleneck of the canned finished ampoule bottle, wherein the detection comprises the following specific steps: taking off the ampoule bottles at the interval of ten, then putting the ampoule bottles into a bottle cap sealing tester for sealing detection, and finally putting unqualified products into S3 for re-capping;
s5: and (3) packaging the filled finished ampoule bottle in a refrigerated cabinet for later use, wherein the temperature in the refrigerated cabinet is controlled to be between-3 and-6 ℃.
Preferably: the qualified standard of the weighed traditional Chinese medicine decoction pieces in the S3 is less than or equal to 50g, an unqualified product label is attached to the corresponding ampoule bottle when the weight of the traditional Chinese medicine decoction pieces is more than 50g, the traditional Chinese medicine decoction pieces in the ampoule bottle are poured out, the ampoule bottle is put into the cleaning machine in the S1 again for cleaning and subsequent use, and the traditional Chinese medicine decoction pieces are crushed and prepared again to meet the corresponding filling requirement.
Preferably: s1, before the ampoule bottle is put into a cleaning machine for cleaning, a disinfectant is poured into the cleaning machine to increase the disinfection effect of the ampoule bottle body and the ampoule bottle, wherein the disinfectant is prepared by the following steps: 1. taking 20% of deionized water, 40% of ethanol and 50% of hydrogen peroxide according to mass percentage, sequentially pouring the raw materials into a transparent glass container with the volume of 4L, and stirring for 5min through a stirring shaft to fully mix the raw materials, the ethanol and the hydrogen peroxide; 2. placing the mixed solution in an environment with the temperature of 50 ℃ for standing for 2 hours; 3. and (3) fully stirring the mixed solution of 6% of glyceryl monostearate by mass for 6min by using a stirring shaft, and standing for 1.5h in an environment with the temperature of 50 ℃ again to fully mix the mixed solution to obtain the finished disinfectant.
Preferably: the cleaning machine in the S1 is an ultrasonic cleaning machine, wherein the cleaning time is 5min, and the cleaning liquid is heated in the cleaning process, wherein the heating temperature is more than 95 ℃.
Preferably: s1, after being cleaned by the disinfectant, the water is cleaned again by clean water, and the water temperature in the two cleaning processes is the same.
Preferably: and the drying temperature of the dryer in the S2 is controlled to be 50-80 ℃, and the drying time is 1-3 min.
The above embodiments are only preferred embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equally replaced or changed within the scope of the present invention.
Claims (6)
1. An aseptic filling method for processing traditional Chinese medicine decoction pieces is characterized by comprising the following steps:
s1: firstly, putting the ampoule bottle into a cleaning machine for cleaning, and driving an inner cylinder in the cleaning machine to rotate by a built-in motor in the cleaning machine in the cleaning process so as to accelerate the cleaning efficiency of the ampoule bottle;
s2: placing the cleaned ampoule bottle in a plastic containing box, wherein the bottle mouth of the ampoule bottle is upward and the bottle bottom of the ampoule bottle is downward in the placing process, then placing the plastic containing box containing the ampoule bottle in a drying machine for drying, and blowing air into a drying bin from top to bottom in the drying process so as to accelerate the drying efficiency of the ampoule bottle body and the ampoule bottle;
s3: placing the dried ampoule bottle in a placing groove formed in a production line, filling traditional Chinese medicine decoction pieces into the ampoule bottle by a filling machine positioned above the placing groove, then carrying out capping treatment on the bottleneck of the ampoule bottle, wherein the ampoule bottle is integrally weighed before being placed in the placing groove, the traditional Chinese medicine decoction pieces are secondarily weighed after being filled, and subtracting the values of the secondary weighing to obtain the weight value of the filled traditional Chinese medicine decoction pieces so as to judge whether the filling weight of the traditional Chinese medicine decoction pieces reaches the standard or not;
s4: the method comprises the following steps of performing sealing detection on the bottleneck of the canned finished ampoule bottle, wherein the detection comprises the following specific steps: taking off five ampoules at intervals, then placing the ampoules into a bottle cap sealing tester for sealing detection, and finally placing unqualified products into S3 for re-capping;
s5: and (3) packaging the filled finished ampoule bottle in a refrigerated cabinet for later use, wherein the temperature in the refrigerated cabinet is controlled to be between-3 and-6 ℃.
2. The aseptic filling method for processing herbal pieces ready for decoction, according to claim 1, wherein the qualification standard of weighing herbal pieces ready for decoction in S3 is less than or equal to 50g, and for more than 50g, an unqualified product label is attached to the corresponding ampoule, the herbal pieces ready for decoction in the ampoule are poured out, the ampoule is put into the cleaning machine in S1 again for cleaning and subsequent use, and for herbal pieces ready for decoction, the ampoule is crushed and prepared again, so as to meet the corresponding filling requirement.
3. The aseptic filling method for herbal pieces processing as claimed in claim 1, wherein before the ampoule is put into the cleaning machine for cleaning in step S1, a disinfectant is poured into the cleaning machine to increase the disinfection effect of the ampoule body and the ampoule interior.
4. The aseptic filling method for decoction pieces of Chinese traditional medicine according to claim 1, wherein said cleaning machine in S1 is an ultrasonic cleaning machine, wherein the cleaning time is 5min, and the cleaning liquid is heated during the cleaning process, wherein the heating temperature is higher than 95 ℃.
5. The aseptic filling method for herbal pieces processing as claimed in claim 1, wherein said S1 is further cleaned again with clean water after being cleaned with sterilizing solution, and the water temperature in the two cleaning processes is the same.
6. The aseptic filling method for processing the Chinese herbal pieces as claimed in claim 1, wherein the drying temperature of the dryer in S2 is controlled to be 50-80 ℃ and the drying time is 1-3 min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010028449.4A CN111152954A (en) | 2020-01-10 | 2020-01-10 | Aseptic filling method for processing traditional Chinese medicine decoction pieces |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010028449.4A CN111152954A (en) | 2020-01-10 | 2020-01-10 | Aseptic filling method for processing traditional Chinese medicine decoction pieces |
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| CN111152954A true CN111152954A (en) | 2020-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010028449.4A Pending CN111152954A (en) | 2020-01-10 | 2020-01-10 | Aseptic filling method for processing traditional Chinese medicine decoction pieces |
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Application publication date: 20200515 |
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