CN111134892A - Capturing and fixing device for abdominal cavity and intramuscular injection operation of experimental rat and using method thereof - Google Patents
Capturing and fixing device for abdominal cavity and intramuscular injection operation of experimental rat and using method thereof Download PDFInfo
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- CN111134892A CN111134892A CN202010123445.4A CN202010123445A CN111134892A CN 111134892 A CN111134892 A CN 111134892A CN 202010123445 A CN202010123445 A CN 202010123445A CN 111134892 A CN111134892 A CN 111134892A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
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Abstract
The invention discloses a catching and fixing device for abdominal cavity and intramuscular injection operation of an experimental rat and a using method thereof, belonging to the technical field of animal experimental devices. The invention relates to a catching and fixing device for abdominal cavity and intramuscular injection operation of experimental rats, which comprises: the external capturing fixer device is provided with a U-shaped groove, and a magnetic controller placing plate is arranged in the external capturing fixer device; two conical sealers for sealing both ends of the external capturing fixture device; an internal fixation device that can be installed into and removed from the external capture fixation device through the adjustment gripping device portion. The invention combines the catching and the fixing of the rat, reduces the experimental steps and is convenient for experimental operation.
Description
Technical Field
The invention belongs to the technical field of animal experiment devices, and particularly relates to a catching and fixing device for abdominal cavity and intramuscular injection operation of experimental rats and a using method thereof.
Background
The animal experiment is a kind of experiment technology commonly used in biology, medicine and pharmacy research, and particularly in the fields of new drug research and development, medicine research and the like, the animal experiment has irreplaceable effects. In animal experiments, rats and mice are commonly used experimental animals, and meanwhile, intraperitoneal injection and intramuscular injection are common experimental methods in animal experiments. The catching, fixing and abdominal cavity or intramuscular injection of the big and small mice, especially rats, can be conveniently and quickly completed, which has very important significance for animal experiments, and further promotes the further development of related research and study.
The defects and shortcomings of the prior art are as follows:
firstly, the method comprises the following steps: at present, the capture of rats is mainly completed by wearing gloves manually, and the success rate of the capture depends on the long-term accumulation of manual capture experience; the rat temperament is fierce, and the worker is bitten by the rat very often in the rat experiment, and the condition not only causes huge influence on the completion of the experiment, but also brings great pain to the physical and mental health of the operator.
Secondly, the method comprises the following steps: in the existing rat abdominal cavity and intramuscular injection process, operators are affected by factors such as experience, sex, gloves and the like, and in the rat fixing process, the rats often escape from fixation and hurt the operators; the rat body is severely twisted, so that the conditions of injection of abdominal cavity, incomplete intramuscular injection operation, needle breakage and the like are caused, and the injury on the body can be caused to both the working personnel and the rat.
The existing rat catching equipment can only catch the rat, manual fixing of workers is needed for later fixing, and part of the catching equipment with complex operation can simply fix the rat but cannot adjust the posture of the body of the rat so as to inject the rat into the abdominal cavity and muscles. In addition, after the experimental operation, the rats were bitten by the rats due to the proximity to the rats.
Therefore, the device has important significance for researching the catching and fixing device used for abdominal cavity and intramuscular injection operation of experimental rats.
Disclosure of Invention
The invention aims to solve the defects of the prior art and provides a catching and fixing device for abdominal cavity and intramuscular injection operation of an experimental rat and a using method thereof.
The invention adopts the following technical scheme:
the invention provides a catching and fixing device for abdominal cavity and intramuscular injection operation of experimental rats, which comprises:
the external capturing fixer device is provided with a U-shaped groove, and a magnetic controller placing plate is arranged in the external capturing fixer device;
two conical sealers for sealing both ends of the external capturing fixture device;
an internal fixation device that can be installed into and removed from the external capture fixation device through the adjustment gripping device portion.
In some of these embodiments, the internal fixation device comprises:
the edge of the fence type curved upper cover is provided with an electromagnetic ring, the top of the fence type curved upper cover is provided with an adjusting holding part, and a soft plastic adjusting part is arranged inside the fence type curved upper cover;
the edge of the fence type micro-curve lower cover is provided with a low-magnetic adsorption ring;
and the magnetic controller is connected with the electromagnetic coil through a connecting wire and can be placed on the magnetic controller placing plate.
In some embodiments, the catching fixture for abdominal and intramuscular injection operation of experimental rat further comprises a lower cover bayonet.
In some embodiments, the adjusting grip is a cylindrical body, and the adjusting grip can slide along the U-shaped groove.
In some embodiments, the flexible plastic regulating member is a circular flexible plastic sheet.
In some of these embodiments, the external capture fixture means is cylindrical.
The invention also provides a using method of the catching and fixing device for the abdominal cavity and intramuscular injection operation of the experimental rat, which comprises the following steps:
catching and preliminary fixing of rats: the fence type micro-curve type lower fixing device is fixed on an external capturing fixer device through a lower cover bayonet device, one end of the external capturing fixer device is sealed by a conical sealer, the external capturing fixer device is placed in a mouse cage, a fence type curved upper cover is conveyed into the external capturing fixer device along a U-shaped groove through adjusting a holding part, the other end of the external capturing fixer device is sealed after a rat enters, the positions of a low-magnetism adsorption ring at the edge of the fence type curved upper cover and the fence type micro-curve type lower cover are adjusted through adjusting the holding part, and a power supply is started through a magnetic controller to enable an electromagnetic ring at the edge of the upper cover of the curved rat fixer to generate magnetism to be adsorbed and closed with the low-magnetism adsorption ring at the edge of the lower cover of the fence type micro-curve type rat fixer; the external capturing fixer device is taken up, the lower cover bayonet is pressed down to be separated from the external capturing fixer device, the conical sealer is taken down, the internal fixing device is taken out along the U-shaped groove, and the fixing of the rat is completed;
intraperitoneal and intramuscular injection of rats: the inner fixing device is held by hands, the index finger and the middle finger clamp the adjusting holding part, the operation is convenient, the prevention and treatment device falls off from the hands, when the posture of the rat needs to be adjusted, the soft plastic adjusting part is pressed by two hands to adjust the posture of the rat, or the soft plastic adjusting part is used for soothing the rat to enable the rat to enter a calm state;
when the abdominal injection is operated, the soft plastic adjusting part is used for adjusting four limbs of the rat to extend out of the fence, so that the four limbs of the rat can be conveniently subjected to intramuscular injection;
release in rats: put into the squirrel cage with inside fixing device, close the power through the magnetic controller, make electromagnetic coil magnetism disappear, and then separate with low magnetism adsorption ring, the rat breaks away from fixedly naturally, waits that the rat leaves the back and opens the power through the magnetic controller, makes electromagnetic coil produce magnetism and low magnetism adsorption ring and produces and adsorb, recovery unit also can retrieve through apparatus or manual work.
Compared with the prior art, the invention has the beneficial effects that:
firstly, the problems that the catching fails and a rat bites a human body and the like possibly caused by manual operation of workers in the animal fixing process are solved;
secondly, the device of the invention combines the catching and fixing of the rat, reduces the experimental steps and facilitates the experimental operation;
thirdly, different from the problem that the posture of the rat body of the conventional rat fixing device is difficult to adjust, the device adopts a soft material to fix the rat body, so that the posture of the rat body is convenient to adjust, and meanwhile, the rat is prevented from being injured by a hard material;
fourthly, the rat is fixed by adopting an electromagnetic adsorption method, the rat is fixed and released through a power switch in the rat fixing and releasing process, and particularly the personal safety of workers is guaranteed in the releasing process.
Drawings
FIG. 1 is a schematic structural view of a catching fixture for abdominal and intramuscular injection operation of experimental rat according to the present invention;
FIG. 2 is a schematic view of the internal fixation device of the present invention;
FIG. 3 is a schematic structural view of a round-nose pliers used in the present invention;
FIG. 4 is a schematic illustration of the injection of the present invention after immobilization of a mouse;
FIG. 5 is a schematic structural view of a lower cover bayonet of the present invention;
FIG. 6 is a schematic structural view of a flexible plastic adjustment member disposed in the barrier curved cover according to the present invention;
FIG. 7 is a schematic view of the configuration of the external capture fixture apparatus of the present invention with both ends unsealed;
FIG. 8 is a schematic view of the external capture fixator apparatus of the present invention with both ends closed;
FIG. 9 is a schematic view of the configuration of the magnetic controller disposed within the external capture fixture apparatus of the present invention;
FIG. 10 is a bottom view of the barrier curved upper cover of the present invention;
FIG. 11 is a top view of the barrier curved lower cover of the present invention;
wherein, 1, an external capture fixator device; 2. a U-shaped groove; 3. a conical sealer; 4. a magnetic controller placement board; 5. a barrier type curved upper cover; 6. a fence type micro-curve lower cover; 7. an electromagnetic coil; 8. a low magnetic adsorption ring; 9. a magnetic controller; 10. a soft plastic adjustment member; 11. an adjustable grip portion; 12. a connecting wire; 13. and a bayonet device is covered at the lower part.
Detailed Description
The present invention is further illustrated by the following examples, which are intended to be purely exemplary and are not intended to limit the scope of the invention, which is defined in the appended claims, as may be amended by those skilled in the art upon reading the present invention.
Example 1
As shown in fig. 1 to 11, the present invention provides a catching fixture for abdominal and intramuscular injection procedures of experimental rats, comprising:
the external capturing fixator device 1 is cylindrical, a U-shaped groove 2 is formed in the external capturing fixator device 1, and a magnetic controller placing plate 4 is arranged in the external capturing fixator device 1;
the two conical sealers 3 are used for sealing two ends of the external capturing and fixing device 1, and the conical sealers 3 are detachably connected with the two ends of the external capturing and fixing device 1, such as in threaded connection or clamping connection;
an internal fixation device, the internal fixation device comprising:
the fence type curved upper cover comprises a fence type curved upper cover 5, an electromagnetic ring 7 is arranged on the edge of the fence type curved upper cover 5, an adjusting holding portion 11 is arranged at the top of the fence type curved upper cover 5, the adjusting holding portion 11 is a cylindrical body, and the adjusting holding portion 11 can slide along the U-shaped groove 2. A flexible plastic adjusting part 10 is arranged inside the fence type curved upper cover 5, and the flexible plastic adjusting part 10 is a round flexible plastic sheet.
The fence type micro-curve lower cover 6 is provided with a low-magnetism adsorption ring 8 at the edge;
a magnetic controller 9, wherein the magnetic controller 9 is connected with the electromagnetic coil 7 through a connecting wire 12, and the magnetic controller 9 can be placed on the magnetic controller placing plate 4. The internal fixation device can be inserted into the external capture fixation device 1 via the adjustment grip device portion 11 and can be removed from the external capture fixation device 1.
The electromagnetic ring 7 mainly uses the adsorption principle of electromagnet, and the magnetic force is introduced into the electromagnetic ring 7 through the micro electromagnet, and then the magnetic force is adsorbed with the low-magnetism adsorption ring 8, the upper part and the lower part are closed, and the adsorption schematic diagram is shown in fig. 6.
Wherein the catching and fixing device for the abdominal cavity and intramuscular injection operation of the experimental rat further comprises a lower cover bayonet device 13, and the lower cover bayonet device 13 is: a round hole is formed in the lower portion of the cylinder of the external catching fixator device 1, a protruding cylinder is arranged on the lower portion of the fence type micro-curve type lower cover 6, the diameter of the protruding cylinder is smaller than that of the round hole formed in the lower portion of the cylinder of the external catching fixator device 1, and the protruding cylinder can extend out of the round hole.
The magnetic controller 9, the electromagnetic ring 7 and the magnetic adsorption ring 8 involved in the device are all existing products, can be purchased directly, have no specific requirements for model, and can be obtained as long as the functions of the invention can be realized, and the following are provided as examples of the purchase sources of the magnetic controller 9, the electromagnetic ring 7 and the magnetic adsorption ring 8:
the electromagnetic coil 7 can be purchased from a commercially available electromagnet, is embedded by iron sheet, is made into the electromagnetic coil 7 by self, is adhered to the edge of the fence type curved upper cover 5 by adhesive glue, and can be purchased from DX1010, Deon electromagnetic technology Co., Ltd, Dongguan; the electromagnetic ring 7 can also be directly purchased with a finished product with a proper size;
the low-magnetic adsorption ring 8 can be purchased from a commercially available magnetic material accessory, such as the accessory of the magnetic material accessory of Ningbo North Lunebele brand WieN35, is manufactured into a ring shape by self and is adhered to the edge of the fence type micro-curve lower cover 6 by adhesive glue; the low-magnetism adsorption ring 8 can also be directly purchased into a finished product with proper size;
the magnetic controller 9 is available from Shenzhen Sendai electronic Limited, model number: LIR2032, 2 CR2032 batteries are matched. Products from other manufacturers may also be purchased.
The invention discloses a using method of a catching and fixing device for abdominal cavity and intramuscular injection operation of an experimental rat, which comprises the following steps:
catching and preliminary fixing of rats: fixing a fence type micro-curve lower cover 6 on an external catching fixer device 1 through a lower cover bayonet 13, sealing one end of the external catching fixer device 1 by using a conical sealer 3, using round-nose pliers as shown in figure 3, putting the external catching fixer device 1 in a mouse cage, sending a fence type curved upper cover 5 into the external catching fixer device 1 along a U-shaped groove 2 through an adjusting holding part 11, sealing the other end of the external catching fixer device 1 after a rat enters, adjusting the positions of the fence type curved upper cover 5 and a low-magnetic adsorption ring 8 at the edge of the fence type micro-curve lower cover through an adjusting holding part 11, and starting a power supply through a magnetic controller 9 to enable an electromagnetic ring 7 at the edge of the fence type mouse upper cover to generate magnetism and adsorb and close with the low-magnetic adsorption ring 8 at the edge of the fence type micro-curve type mouse lower cover through a magnetic controller 9; the external capturing fixator device 1 is taken up, the lower cover bayonet device 13 is pressed down to be separated from the external capturing fixator device 1, the conical sealer 3 is taken down, the internal fixator is taken out along the U-shaped groove 2, and the rat is fixed;
intraperitoneal and intramuscular injection of rats: the inner fixing device is held by hands, the adjusting holding part 11 is clamped by the index finger and the middle finger, the operation is convenient, the prevention and treatment device falls off from the hands, when the posture of the rat needs to be adjusted, the posture of the rat is adjusted by pressing the soft plastic adjusting part 10 by two hands, or the rat is pacified by the soft plastic adjusting part 10, so that the rat enters a calm state;
when the abdominal injection is operated, the rats are properly pressed through the soft plastic adjusting part 10 according to the size of the rats, so that the chest and abdomen parts of the rats are tightly attached to the fence type micro-curve lower cover 6 to facilitate the operation, and when the abdominal injection is performed, four limbs of the rats are adjusted through the soft plastic adjusting part 10 to extend out of the fence, so that the four limbs of the rats are conveniently subjected to intramuscular injection;
release in rats: put into the squirrel cage with inside fixing device, close the power through magnetic controller 9, make 7 magnetism of electromagnetic ring disappear, and then with the separation of low magnetism adsorption ring 8, the rat breaks away from fixedly naturally, treat that the rat leaves the back and open the power through magnetic controller 9, make electromagnetic ring 7 produce magnetism and low magnetism adsorption ring 8 and produce and adsorb, recovery unit also can be retrieved through apparatus or manual work.
The embodiments of the present invention have been described in detail with reference to the above examples, but the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the scope of the present invention, which is defined in the appended claims.
Claims (7)
1. A capturing and fixing device for abdominal and intramuscular injection operation of experimental rat, characterized by comprising:
the device comprises an external capturing fixer device (1), wherein a U-shaped groove (2) is formed in the external capturing fixer device (1), and a magnetic controller placing plate (4) is arranged in the external capturing fixer device (1);
two conical closures (3), the conical closures (3) being for closing both ends of the external capture fixture device (1);
an internal fixing device which can be inserted into the external catching holder device (1) by means of the adjusting grip device part (11) and can be removed from the external catching holder device (1).
2. The catch fixture for laboratory rat intraperitoneal and intramuscular injection procedures according to claim 1, wherein the internal fixture comprises:
the device comprises a fence type curved upper cover (5), wherein an electromagnetic coil (7) is arranged at the edge of the fence type curved upper cover (5), an adjusting holding part (11) is arranged at the top of the fence type curved upper cover (5), and a soft plastic adjusting part (10) is arranged inside the fence type curved upper cover (5);
the fence type micro-curve lower cover (6) is provided with a low magnetic adsorption ring (8) at the edge;
the magnetic controller (9), the magnetic controller (9) is connected with the electromagnetic coil (7) through a connecting wire (12), and the magnetic controller (9) can be placed on the magnetic controller placing plate (4).
3. Catching fixture for laboratory rat abdominal and intramuscular injection procedures according to claim 2, characterized by further comprising a lower lid bayonet (13).
4. Catching fixture for laboratory rat abdominal and intramuscular injection procedures according to claim 1 characterized by the fact that the adjustment grip (11) is a cylindrical body and the adjustment grip (11) is slidable along the U-shaped groove (2).
5. Catching fixture for laboratory rat abdominal and intramuscular injection procedures as claimed in claim 1 characterized by the soft plastic adjustment part (10) being a round soft plastic sheet.
6. Catching fixture device for laboratory rat abdominal and intramuscular injection procedures according to claim 1 characterized by the fact that the external catching fixture device (1) is cylindrical.
7. The method of using the catching fixture for the intraperitoneal and intramuscular injection operation of experimental rats as set forth in claim 3, wherein the steps are as follows:
catching and preliminary fixing of rats: the fence type micro-curve type lower cover (6) is fixed on the external catching fixer device (1) through the lower cover bayonet device (13), one end of the external catching fixer device (1) is sealed by the cone type sealer (3), the external catching fixer device (1) is put in the squirrel cage, the fence type curved upper cover (5) is sent into the external catching fixer device (1) along the U-shaped groove (2) by adjusting the holding part (11), the other end of the external catching fixer device (1) is closed after the rat enters, the positions of the fence type curved upper cover (5) and the low-magnetism adsorption ring (8) at the edge of the fence type micro-curved lower cover are adjusted by adjusting the holding part (11), the power supply is turned on through the magnetic controller (9), so that the electromagnetic ring (7) at the edge of the upper cover of the curved rat fixer generates magnetism and the low-magnetism adsorption ring (8) at the edge of the lower cover of the fence-type micro-curved rat fixer is adsorbed and closed; the external capturing fixator device is taken up, the lower cover bayonet (13) is pressed down to be separated from the external capturing fixator device (1), the conical sealer (3) is taken down, the internal fixator device is taken out along the U-shaped groove (2), and the fixing of the rat is completed;
intraperitoneal and intramuscular injection of rats: the inner fixing device is held by hands, the index finger and the middle finger clamp the adjusting holding part (11), when the posture of the rat needs to be adjusted, the soft plastic adjusting part (10) is pressed by two hands to adjust the posture of the rat, or the soft plastic adjusting part (10) is used for soothing the rat to enable the rat to enter a calm state;
when the abdominal injection is operated, the rat is properly pressed through the soft plastic adjusting part (10) according to the size of the rat, so that the chest and abdomen of the rat are tightly attached to the fence type micro-curve lower cover (6) to facilitate the operation, and when the abdominal injection is operated, the four limbs of the rat are adjusted through the soft plastic adjusting part (10), so that the four limbs of the rat extend out of the fence, and the four limbs of the rat are conveniently subjected to intramuscular injection;
release in rats: the internal fixing device is placed into a mouse cage, the power supply is turned off through the magnetic controller (9), the magnetism of the electromagnetic ring (7) disappears, the electromagnetic ring is separated from the low-magnetism adsorption ring (8), a rat is naturally separated and fixed, the power supply is turned on through the magnetic controller (9) after the rat leaves, the electromagnetic ring (7) generates magnetism and the low-magnetism adsorption ring (8) generates adsorption, and the recovery device can also be recovered through instruments or manpower.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010123445.4A CN111134892A (en) | 2020-03-03 | 2020-03-03 | Capturing and fixing device for abdominal cavity and intramuscular injection operation of experimental rat and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010123445.4A CN111134892A (en) | 2020-03-03 | 2020-03-03 | Capturing and fixing device for abdominal cavity and intramuscular injection operation of experimental rat and using method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111134892A true CN111134892A (en) | 2020-05-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010123445.4A Pending CN111134892A (en) | 2020-03-03 | 2020-03-03 | Capturing and fixing device for abdominal cavity and intramuscular injection operation of experimental rat and using method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111134892A (en) |
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2020
- 2020-03-03 CN CN202010123445.4A patent/CN111134892A/en active Pending
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