CN111134833A

CN111134833A - Tumor ablation device

Info

Publication number: CN111134833A
Application number: CN202010034936.1A
Authority: CN
Inventors: 王三乐
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-01-05
Filing date: 2020-01-05
Publication date: 2020-05-12

Abstract

The invention relates to a medical instrument for treating tumors. The apparatus includes an ablator and a temperature regulating device. The ablator includes a catheter and an ablation needle. The temperature of the needle head of the ablation needle is regulated by a temperature regulating device. The conduit comprises a deformable metal hose, and a rubber hose is arranged outside the metal hose. When the tumor is treated, the needle head of the ablation needle is heated to a certain temperature by an alcohol lamp, then one end of the catheter is aligned with the tumor, and the high-temperature ablation needle is inserted into the tumor along the catheter. Tumor tissue is destroyed instantaneously under high temperature. When the medical apparatus is used for treatment, the treatment time is short, the tumor is eliminated completely, the treatment cost is low, the side effect is small, and the pain of a patient is reduced; can not only treat tumors in superficial regions of human body, but also bend and deform to penetrate deep into organs to treat tumors in deep organs.

Description

Tumor ablation device

Technology neighborhood

The invention relates to a medical instrument for treating tumors.

Background

Currently, therapies for treating tumors may include: drug, surgical removal, chemotherapy, radiotherapy or ablation. Ablation is a physical therapy that surgically removes or destroys abnormal tissue or tumors. Thermal ablation destroys the target tissue by raising its temperature. The ablated tissue may be absorbed by the body or surgically removed from the body. Several different tumor ablations are currently available.

Radiofrequency ablation generates thermal energy from an electrical current. One or more electrodes or conductors are placed on the target tissue and an electrical current is passed directly through the one or more electrodes to heat the target tissue. However, radiofrequency ablation may cause a heat sink effect on the target tissue. For target tissue diameters greater than 3 cm, the effectiveness of radiofrequency ablation is limited. U.S. patent No. 8,430,870 and U.S. patent No. 8,491,578 disclose a radio frequency ablation device that includes a ferromagnetic layer covering a portion of a conductor.

Microwave ablation uses microwaves to raise the temperature of the target tissue. One or more probes are placed on the target tissue and microwave energy is delivered to the target tissue to generate thermal energy. However, microwave ablation may also cause a heat sink effect on the target tissue. When using microwave ablation, it is difficult to control the ablation region, which may lead to unnecessary tissue damage. Blood loss from the target tissue during microwave ablation may also be difficult to control.

Laser ablation uses a laser to evaporate water molecules and hemoglobin in the target tissue or to cut the target tissue. However, the ablation area for laser ablation is small compared to microwave ablation or radio frequency ablation. Another limitation of laser ablation is that the ablation effect can only reach superficial regions of the target tissue. Yet another limitation of laser ablation is that it requires a longer treatment time to perform the ablation. A longer treatment time represents a higher risk for the procedure to the individual receiving the ablation procedure.

Cryoablation induces hypothermia with one or more cryoprobes to destroy the target tissue. The cryoprobes rapidly lower the temperature of the target tissue, thereby allowing the formation of intracellular ice crystals to irreversibly damage the target tissue. However, cryoablation can create a severe heat sink effect during the procedure.

Electromagnetic thermal therapy uses a magnetic field to increase the temperature of one or more probes or needles. Further, the current in the coil assembly may generate an electromagnetic field that induces current to be generated in one or more metal probes or pins, thereby increasing the temperature of the metal probes or pins. However, the coil assembly, which generates the electromagnetic field, is of a size that is not convenient for the physician to use. U.S. patent application No. 20050251126, U.S. patent No. 8,361,060, U.S. patent application No. 20110054455, and U.S. patent No. 9,095,329 disclose electromagnetic thermal therapy apparatus having at least one coil assembly and a ferrous needle.

There are also other thermal ablation therapies currently available for the treatment of cancer or benign tumors. U.S. patent application No. 20090216220, U.S. patent No. 8,251,985, U.S. patent No. 8,419,723, U.S. patent application No. 2010014536, U.S. patent No. 8,388,611, U.S. patent application No. 20100179416, and U.S. patent application No. 20110077628 apply for thermal ablation devices that use high temperature liquids or vapors to heat target tissue. U.S. patent No. 6780,177, U.S. patent No. 6,872,203, and U.S. patent application No. 20060167445 disclose thermal ablation devices that use resistive heating.

Chinese patent application No. 201780029411.5, an electric heating needle tool capable of quickly producing heat is applied. Because of its non-deformable shape, it is difficult to directly treat tumors inside organs, such as esophageal tumors, rectal tumors, cervical tumors, and throat tumors.

Disclosure of Invention

The purpose of the invention is: aiming at tumor diseases, the ablation instrument can treat tumors in superficial regions of human bodies, can also be bent and deformed to penetrate deep into organs and treat tumors of various organs.

In order to achieve the purpose, the invention provides the following technical scheme: the medical device includes an ablator and a temperature regulating device. The ablator includes a catheter and an ablation needle. The temperature of the needle head of the ablation needle is regulated by a temperature regulating device. The conduit comprises a deformable metal hose, and a rubber hose is arranged outside the metal hose. The ablation needle comprises a length of flexible metallic cord.

In one embodiment, the diameter of one end of the metal hose is larger than that of the other end; the metal soft rope is a steel rope, and one end of the steel rope is welded with metal.

In one embodiment, the temperature regulating device comprises a temperature heating device, a cooling device and a temperature detecting device.

In one embodiment, the metal hose has a bend-sizing feature.

In one embodiment, the metal hose is composed of an extension spring and a compression spring.

In one embodiment, one end of the metal hose is beveled and the end of the metal hose is oval.

In one embodiment, the rubber hose is an elastic membrane having thickened ends.

In one embodiment, the ablator is equipped with an illuminator and a camera, which is connected to an image display.

In one embodiment, the ablator comprises a set of delivery devices.

In one embodiment, the catheter of the tumor ablator is positioned alongside the gastroscopic insertion tube.

When the tumor is treated, the needle head of the ablation needle is heated to a certain temperature by an alcohol lamp under the detection of a temperature detection device, then one end of the catheter is aligned with the tumor, and the high-temperature ablation needle is inserted into the tumor along the catheter. Tumor tissue is destroyed instantaneously under high temperature. When treating deep tumor of organ, the ablation needle head is first heated to certain temperature by alcohol lamp under the detection of the temperature detector, then the catheter is passed through the open end of the organ and passed along the organ channel to reach the tumor, and then the high temperature ablation needle is inserted into the tumor along the catheter. High temperature is generated around the ablation needle, and the tumor tissue is carbonized and ablated instantly at the high temperature of more than 300 ℃. In the environment of more than 60 ℃, the cell membrane can be destroyed in a few seconds, the enzyme protein is denatured, and the cells completely lose activity. Unlike radiation therapy, acupuncture is an immediate destruction of tumor tissue. At the same time, the blood vessel of the tissue around the tumor coagulates to form a reaction zone, so that the tumor loses blood supply and the tumor metastasis and bleeding are prevented. When the medical apparatus is used for treatment, the treatment time is short, the tumor is eliminated completely, the treatment cost is low, the side effect is small, and the pain of a patient is reduced; can not only treat tumors in superficial regions of human body, but also tumors in deep organs.

Drawings

FIG. 1 is a cross-sectional view of a catheter in accordance with one embodiment of the present invention.

Fig. 2 is a schematic view of an ablation needle according to an embodiment of the present invention.

Fig. 3 is a schematic structural view of an ablator in accordance with an embodiment of the present invention.

Fig. 4 is a schematic view of a connection structure of a rubber hose and a metal hose according to an embodiment of the present invention.

Fig. 5 is a schematic structural view of an ablator, in accordance with an embodiment of the present invention.

Fig. 6 is a schematic view of a connection structure of a catheter, an illuminating element and a camera according to an embodiment of the invention.

Fig. 7 is a schematic structural view of an ablator, in accordance with an embodiment of the present invention.

FIG. 8 is a schematic view of a metal hose according to an embodiment of the present invention.

Fig. 9 is a schematic view of a connection structure of a catheter, an illuminating element and a camera according to an embodiment of the invention.

FIG. 10 is a schematic view showing a connection structure of a catheter and a gastroscope insertion tube according to an embodiment of the present invention.

FIG. 11 is a schematic view of a catheter administration device according to an embodiment of the present invention.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.

Please refer to fig. 1, fig. 2, fig. 3, and fig. 4. In one embodiment, the ablator is designed as follows: the medical device of the invention consists of an ablator 1 and a heating device. The ablator 1 comprises a catheter 2 and an ablation needle 3. The temperature regulating device comprises an alcohol lamp and a temperature measuring device. The needle head of the ablation needle is heated to a certain temperature by an alcohol lamp under the detection of the temperature detection device. The conduit 2 is composed of a bent metal hose 4 and a rubber hose 5. The ablation needle 3 is a section of deformable metal soft cable 6, one end of the metal soft cable is welded with metal copper, the section welded with the metal copper is called an ablation needle head 7, and the ablation needle head is ground into a cylinder. The end of the metal cord fitted with the handle is called the handle 8. For example, in the treatment of oral tumors. Firstly, the ablation needle head 7 is heated to a certain temperature by an alcohol lamp under the detection of the temperature detection device. Then, according to the tumor position, the catheter 2 is bent and shaped to a proper shape, one end of the catheter is aligned with the tumor, and the high-temperature ablation needle is inserted into the tumor along the other end of the catheter. Tumor tissue is destroyed instantaneously under high temperature.

Please refer to fig. 5 and fig. 6. In one embodiment, the ablator is designed as follows: the ablator is provided with an illuminator 10 and a camera 11, which is connected to an image display. The term "connected" is to be understood broadly, and may include, for example, a fixed connection or a removable connection; or indirectly connected through WIFI. The conduit 2 employs a flexible metal hose 4. The diameter of one end of the metal hose is larger than that of the other end of the metal hose. The ablation needle is a length of flexible wire 9. In order to enable the heat transfer of the high-temperature ablation needle to be faster when the high-temperature ablation needle is close to the tumor, metal silver is welded at one end of the steel cable. Here "soldering" includes an electroplating process. The section to which the metallic silver is welded is called an ablation needle head 7. The head of the ablation needle is polished into a cone shape. A compression spring 14 is provided at the handle. The compression spring 14 is provided for convenient operation by one hand, and is beneficial to returning the handle 8 when a point-contact method is adopted to ablate the tumor. For example, when treating a laryngeal tumor, the ablation needle head 7 is heated to a certain temperature by an alcohol lamp under the detection of the temperature detection device, then the catheter 2 is bent and shaped to a proper shape under the guidance of the camera and according to the tumor part, one end of the catheter is aligned with the tumor, and the high-temperature ablation needle is inserted into the tumor along the other end of the catheter. The tumor tissue is thermally ablated.

Please refer to fig. 7, 8, and 9. For example, for the requirement of esophageal tumor ablation, the ablator adopts the following design: an illuminator 10 and a camera 11 are provided on the ablator. The camera is connected with the image display. The term "connected" is to be understood broadly, and may include, for example, a fixed connection or a removable connection; or indirectly connected through WIFI. The diameter of one end of the metal hose is larger than that of the other end of the metal hose. The illuminating piece is arranged beside the camera, so that the cross-sectional area of the insertion end of the ablator can be effectively reduced; the rubber hose 5 is an elastic film, the end part of the rubber hose is thickened, and the thickness of the elastic film is 0.3-0.5 mm; the thickness of the catheter 2 can be effectively reduced by an elastic membrane having a thickness of 0.3-0.5mm, which is designed to facilitate insertion of the catheter into the esophagus. For improved safety, the rubber hose 5 has a thickened end 12. For example, thickened end portions 12 are provided at both ends and in the middle of the rubber hose 5. For example, the cross-sectional area of the thickened end portion 12 is 1.3 to 1.6 times the cross-sectional area of the other portion of the rubber hose 5. Preferably, the cross-sectional area of the thickened end portion 12 is 1.5 times the cross-sectional area of the other portion of the rubber hose 5. Thus, the elastic film can be effectively prevented from being split from both ends by thickening the end portion 12, and the safety of the use of the rubber hose 5 is improved. The metal hose is composed of a soft extension spring 13 and a compression spring 14. The flexible extension spring 13 is used for the metal hose to prevent tissue damage when inserted into the esophagus. The compression spring 14 is provided for convenient operation by one hand, and is beneficial to returning the handle 8 when a point-contact method is adopted to ablate the tumor. One end of the metal hose is processed into an inclined plane, and the end port of the metal hose is oval, so that the design is favorable for the insertion of the needle head 7 of the ablation needle into the root of the tumor.

Please refer to fig. 10. For example, for the requirement of stomach tumor ablation, the ablator adopts a use method that when in use, the sleeve 15 is rolled into a ring shape, and after the ablator catheter 2 and the gastroscope insertion tube 16 are inserted into the ring-shaped sleeve 15, the ablator catheter 2 and the gastroscope insertion tube 16 can be sleeved by pushing the ring-shaped elastic film. During treatment, the ablator catheter 2 along with the gastroscope insertion tube 16 extends into the stomach organ through the esophagus, and under the guidance of the gastroscope image, the tumor is treated.

Referring to FIG. 11, in one embodiment, the tumor site is inflamed, infected, bleeding for prevention and treatment. The invention designs a medicine applying device matched with an ablator. For example, the apparatus is provided with a nozzle 17, a spray head 18 and a squeezing device 19. The outer diameter of the lance 17 is smaller than the inner diameter of the conduit. When in application, liquid or powder medicine is loaded into the extrusion device 19, the extrusion device 19 is connected with the spray head 18, the spray head 18 is connected with the spray pipe 17, and the spray pipe 17 is inserted into the conduit and reaches the tumor treatment part along the conduit. The compression device is then manipulated to cause the medicament to reach the affected area.

In one embodiment cryoablation is used. And cooling the needle head of the ablation needle to a certain temperature in liquid nitrogen under the detection of a temperature detection device. Then, the ablation needle is inserted into the tumor along the catheter, and the tumor is subjected to cryotherapy. Cryotherapy is a complex effect of cryobiology. Cells are irreversibly damaged in the extremely frozen state. It is used in extremely frozen state to kill the cells in the disease area fast and restore the disease area normally.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A tumor ablator for ablating tumor tissue by changing the temperature of the tumor tissue, comprising: the medical device comprises an ablator and a temperature regulating device; the ablator comprises a catheter and an ablation needle; the conduit comprises a section of deformable metal hose, and a section of rubber hose is arranged outside the metal hose; the ablation needle comprises a length of flexible metallic cord.

2. A tumor ablator according to claim 1, wherein: the diameter of one end of the metal hose is larger than that of the other end of the metal hose; the metal soft rope is a steel rope, and one end of the steel rope is welded with metal.

3. A tumor ablator according to claim 1, wherein: the temperature adjusting device comprises a temperature heating device, a refrigerating device and a temperature detecting device.

4. A tumor ablator according to claim 1, wherein: the metal hose has the characteristic of bending and shaping.

5. A tumor ablator according to claim 1, wherein: the metal hose is composed of an extension spring and a compression spring.

6. A tumor ablator according to claim 1, wherein: one end of the metal hose is processed into an inclined plane, and the port of the metal hose is oval.

7. A tumor ablator according to claim 1, wherein: the rubber hose is an elastic film and is provided with a thickened end part.

8. A tumor ablator according to claim 1, wherein: and the camera is connected with the image display.

9. A tumor ablator according to claim 1, wherein: comprises a set of drug delivery device.

10. A tumor ablator according to claim 1: it is characterized in that the catheter of the tumor ablator is arranged side by side with the gastroscope.