CN111096744A - Novel electroencephalogram signal acquisition implementation device and method - Google Patents

Novel electroencephalogram signal acquisition implementation device and method Download PDF

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Publication number
CN111096744A
CN111096744A CN202010069675.7A CN202010069675A CN111096744A CN 111096744 A CN111096744 A CN 111096744A CN 202010069675 A CN202010069675 A CN 202010069675A CN 111096744 A CN111096744 A CN 111096744A
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electroencephalogram
signal acquisition
novel
electroencephalogram signal
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马宏炎
丁衍
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Suzhou Xiaolan Medical Technology Co ltd
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Suzhou Xiaolan Medical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/377Electroencephalography [EEG] using evoked responses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064Evaluating the brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/04Babies, e.g. for SIDS detection
    • A61B2503/045Newborns, e.g. premature baby monitoring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • A61B2562/0215Silver or silver chloride containing

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  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Psychology (AREA)
  • Psychiatry (AREA)
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  • Physiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Hospice & Palliative Care (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The invention discloses a novel electroencephalogram signal acquisition implementation device, which comprises: the electroencephalogram electrode slice sequentially comprises a foam layer, a PET membrane layer, a circuit layer, an insulating film layer and an adhesive layer from bottom to top, wherein a plurality of collecting points are arranged on the circuit layer, a gel layer is arranged on the insulating film layer, the gel layer is positioned at the same position as the collecting points, and the gel layer is in contact with the skin of a wearer; and the upper computer is connected with the electroencephalogram electrode slice to acquire electroencephalogram signals. The invention also discloses a novel electroencephalogram signal acquisition implementation method, and the electroencephalogram signal acquisition is stable and reliable by combining a special product structure design and an event-related potential superposition technical principle with the neonatal brain electrode slice. The electroencephalogram electrode plate is very convenient to wear, use and remove for the neonate, and has no side effect on the skin of the neonate.

Description

Novel electroencephalogram signal acquisition implementation device and method
Technical Field
The invention relates to the technical field of medical equipment, in particular to a novel electroencephalogram signal acquisition implementation device and a method thereof.
Background
The term "neonatal" refers to the adaptation phase of the fetus from the delivery of the fetus from the mother's uterus to the external life, since the development of the functions of the organs of the neonatal body system is not yet mature. The newborn has low immunologic function, poor body temperature regulating function, easy infection and skin stimulation, and care must be careful, scientific and reasonable. In addition, the clothes for the newborn are loose as much as possible, do not interfere with the movement of limbs and are easy to wear and take off; because the newborn generally sleeps for 18-20 hours every day, the head is high in heat dissipation, the head is soft, and the newborn needs to be soft and comfortable when wearing a small hat.
However, the common electroencephalogram monitoring generally adopts the design of an electroencephalogram cap, the skin of a newborn cannot be stimulated, the sleeping time is long, the head is soft, and the electroencephalogram cap is inconvenient to wear, use and remove for the newborn.
Therefore, the present inventors have earnestly demanded to conceive a new technology to improve the problems thereof.
Disclosure of Invention
The invention aims to provide a novel electroencephalogram signal acquisition implementation device and a novel electroencephalogram signal acquisition implementation method, which can provide hardware and software support for solving the technical problems.
The technical scheme of the invention is as follows:
a novel electroencephalogram signal acquisition implementation device comprises:
the electroencephalogram electrode slice comprises a foam layer, a PET membrane layer, a circuit layer, an insulating film layer and an adhesive layer from bottom to top in sequence, wherein a plurality of collecting points are arranged on the circuit layer, the foam layer, the PET membrane layer and the insulating film layer are matched with the circuit layer in shape, the gel layer is arranged on the insulating film layer, the position of the gel layer is consistent with the position of the collecting points, and the gel layer is in contact with the skin of a wearer;
and the upper computer is connected with the electroencephalogram electrode slice to acquire electroencephalogram signals.
Preferably, the adhesive layer is a medical conductive gel layer.
Preferably, the circuit layer is a silver paste circuit layer.
Preferably, the circuit layer is a carbon layer circuit.
A novel electroencephalogram signal acquisition implementation method comprises the following steps:
s1: attaching the electroencephalogram electrode plate to the skin of a wearer;
s2: applying or removing stimulation to the brain region of the wearer, causing a change in electrical potential in the brain region, and then acquiring electroencephalogram signals by a superposition technique.
Preferably, the step S2 specifically includes:
s21: applying a plurality of repeated stimuli to the wearer;
s22: superposing and averaging the EEG containing the ERP generated by each stimulation;
s23: and extracting the superposed ERP from the EEG background to obtain an electroencephalogram signal.
By adopting the technical scheme, the invention at least comprises the following beneficial effects:
the novel electroencephalogram signal acquisition implementation device and the novel electroencephalogram signal acquisition implementation method are combined with the neonatal brain electrode slice by special product structure design and by utilizing the principle of an Event Related Potential (ERP) superposition technology, so that the neonatal brain electrical system is stably and reliably acquired. The electroencephalogram electrode plate is very convenient to wear, use and remove for the neonate, and has no side effect on the skin of the neonate.
Drawings
Fig. 1 is a schematic structural diagram of a novel electroencephalogram signal acquisition implementation device according to the present invention;
fig. 2 is an exploded structural view of the novel electroencephalogram signal acquisition implementation device;
fig. 3 is a flowchart of a method for acquiring electroencephalogram signals according to the present invention.
Wherein: 1. the composite film comprises a foam cotton layer, 2. a PET membrane layer, 3. a circuit layer, 4. an insulating film layer, 5. an adhesive layer and 6. an electroencephalogram electrode plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
As shown in fig. 1 to 2, a novel electroencephalogram signal acquisition implementation device according to the present embodiment includes:
the electroencephalogram electrode plate 6 sequentially comprises a foam layer 1, a PET membrane layer 2, a circuit layer 3, an insulating membrane layer 4 and an adhesive layer 6 from bottom to top, a plurality of collecting points are arranged on the circuit layer 3, the foam layer 1, the PET membrane layer 2 and the insulating membrane layer 4 are matched with the circuit layer 3 in shape, and a gel layer is arranged on the insulating membrane layer 4 and is in the same position as the collecting points and is in contact with the skin of a wearer through the gel layer;
the upper computer is connected with the electroencephalogram electrode plate 6, applies stimulation or removes stimulation to the brain area of the wearer through the electroencephalogram electrode plate 6, causes potential change in the brain area, and then obtains electroencephalogram signals through a superposition technology.
Preferably, the adhesive layer 6 is a medical conductive gel layer.
Preferably, the circuit layer 3 is a silver paste circuit layer 3.
Preferably, the wiring layer 3 is a carbon layer wiring.
The electroencephalogram electrode plate 6 in the embodiment is an electrode plate formed by PET (polyethylene terephthalate), medical conductive gel and foam cotton which adopt silver paste circuits. The characteristics of the silver paste circuit are as follows: conductivity (antistatic property), adhesion, printability, solvent resistance, and the like. The film switch and the flexible circuit board with PET as the base material generally use silver paste as the conducting circuit. The medical conductive gel is a water-based polymer gel, has high light transmittance and strong conductive sound conductivity, does not irritate the skin, does not damage a probe, and is an ideal ultrasonic and conductive medium. Convenient use, no corrosion, no irritation, no allergy, no pollution, and easy cleaning.
The embodiment is particularly suitable for brain electrical acquisition of a newborn; silver thick liquid circuit in this structure can be replaced by the carbon layer circuit. Electroencephalograms are the general reflection of electrical activity on the surface of the cerebral cortex or scalp during brain nerve cell activity, and are important means for studying brain diseases, brain cognition and brain rehabilitation. The neonate brain electrode sheet 6 in this embodiment provides flexibility and practicality for the electroencephalogram acquisition instrument. The stability and reliability of analyzing the characteristics of the electroencephalogram signals are enhanced. The accuracy of the electroencephalogram signal recorded by the electroencephalogram acquisition instrument is realized.
Example 2
As shown in fig. 2, the implementation method for acquiring a novel electroencephalogram signal according to the present embodiment includes the following steps:
s1: attaching the electroencephalogram electrode plate 6 to the skin of a wearer; the brain electrode pad 6 is preferably the brain electrode pad 6 described in embodiment 1.
S2: applying or removing stimulation to the brain region of the wearer, causing a change in electrical potential in the brain region, and then acquiring electroencephalogram signals by a superposition technique.
Preferably, the step S2 specifically includes:
s21: applying a plurality of repeated stimuli to the wearer;
s22: superposing and averaging the EEG containing the ERP generated by each stimulation;
s23: and extracting the superposed ERP from the EEG background to obtain an electroencephalogram signal.
Event Related Potential (ERP) generally refers to the change in potential in the brain area caused by applying a specific stimulus to a certain part of the sensory system or brain and applying or removing the stimulus.
The superposition technical principle of the collected Event Related Potential (ERP) is as follows:
since the components of the spontaneous potential (EEG) are complex and irregular, the amplitude of ERP induced by one-time stimulation is about 2-10 uV, which is much smaller than that of the spontaneous potential (EEG), and the ERP is submerged in the EEG, and the ERP and the EEG form the relationship between a small signal and a large noise, so that the ERP cannot be directly measured and researched, the ERP needs to be extracted from the EEG.
To extract ERP from EEG, the subject is repeatedly stimulated with "S" a number of times. The ERP containing EEG generated by each stimulus was overlaid and averaged. Since there is no fixed relationship between the EEG waveform as the ERP background and the stimulus, and the ERP waveform contained therein is the same after each stimulus, and the time interval (latency) between the ERP waveform and the stimulus is fixed, the ERP increases in proportion to the number of times of superimposition by superimposition, and the EEG is summed up in a random noise manner. Thus, the superimposed ERP emerges from the EEG background.
In the embodiment, the collection of the neonatal brain electrical system is realized by combining a superposition technology principle of Event related potential (ERP for short) with a novel neonatal brain electrode plate 6. The electrode of the electroencephalogram acquisition system is very convenient to wear, use and remove from a newborn, the electroencephalogram electrode plate 6 is in good contact with the skin, and the stability of signal acquisition is improved. Has no side effect on neonatal skin.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (6)

1. A novel electroencephalogram signal acquisition implementation device is characterized by comprising:
the electroencephalogram electrode slice comprises a foam layer, a PET membrane layer, a circuit layer, an insulating film layer and an adhesive layer from bottom to top in sequence, wherein a plurality of collecting points are arranged on the circuit layer, the foam layer, the PET membrane layer and the insulating film layer are matched with the circuit layer in shape, the gel layer is arranged on the insulating film layer, the position of the gel layer is consistent with the position of the collecting points, and the gel layer is in contact with the skin of a wearer;
and the upper computer is connected with the electroencephalogram electrode slice to acquire electroencephalogram signals.
2. The novel electroencephalogram signal acquisition implementation device of claim 1, wherein: the viscose layer is a medical conductive gel layer.
3. The novel electroencephalogram signal acquisition implementation device of claim 1 or 2, wherein: the circuit layer is a silver paste circuit layer.
4. The novel electroencephalogram signal acquisition implementation device of claim 1 or 2, wherein: the circuit layer is a carbon layer circuit.
5. A novel method for realizing electroencephalogram signal acquisition is characterized by comprising the following steps:
s1: attaching the electroencephalogram electrode plate to the skin of a wearer;
s2: applying or removing stimulation to the brain region of the wearer, causing a change in electrical potential in the brain region, and then acquiring electroencephalogram signals by a superposition technique.
6. The method for implementing the novel electroencephalogram signal acquisition according to claim 5, wherein the step S2 specifically includes:
s21: applying a plurality of repeated stimuli to the wearer;
s22: superposing and averaging the EEG containing the ERP generated by each stimulation;
s23: and extracting the superposed ERP from the EEG background to obtain an electroencephalogram signal.
CN202010069675.7A 2020-01-21 2020-01-21 Novel electroencephalogram signal acquisition implementation device and method Pending CN111096744A (en)

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Publication number Priority date Publication date Assignee Title
CN203059685U (en) * 2012-12-03 2013-07-17 徐金义 Child electrocardiogram chest lead electrode
CN104161507A (en) * 2014-08-29 2014-11-26 东莞市万康医疗器械有限公司 Electrocardiogram conductive connecting line electrode
CN104545900A (en) * 2014-12-29 2015-04-29 中国医学科学院生物医学工程研究所 Event related potential analyzing method based on paired sample T test
CN104615887A (en) * 2015-02-05 2015-05-13 广州市润杰医疗器械有限公司 Voice-image matching method for detecting cognitive function of child
CN204520667U (en) * 2015-01-16 2015-08-05 吕晶 A kind of magnetic self-adhesive medical electrode slice
CN106923816A (en) * 2017-03-10 2017-07-07 苏州格林泰克科技有限公司 A kind of biopotential electrode with flexible cable
CN207055487U (en) * 2017-02-13 2018-03-02 浙江普可医疗科技有限公司 Disposable wireless encryption eeg sensor
CN207236786U (en) * 2017-03-10 2018-04-17 武汉格林泰克科技有限公司 Disposable anesthesia depth monitoring sensor
CN207870892U (en) * 2017-09-19 2018-09-18 河南驼人医疗器械集团有限公司 One kind being used for neonatal EEG signals detection device
CN208492091U (en) * 2017-12-13 2019-02-15 浙江普可医疗科技有限公司 Disposable multi-parameter eeg sensor
CN209770365U (en) * 2019-01-25 2019-12-13 中国福利会国际和平妇幼保健院 Disposable neonatal limb lead electrode plate
CN211749604U (en) * 2020-01-21 2020-10-27 苏州小蓝医疗科技有限公司 Novel electroencephalogram signal acquisition implementation device

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203059685U (en) * 2012-12-03 2013-07-17 徐金义 Child electrocardiogram chest lead electrode
CN104161507A (en) * 2014-08-29 2014-11-26 东莞市万康医疗器械有限公司 Electrocardiogram conductive connecting line electrode
CN104545900A (en) * 2014-12-29 2015-04-29 中国医学科学院生物医学工程研究所 Event related potential analyzing method based on paired sample T test
CN204520667U (en) * 2015-01-16 2015-08-05 吕晶 A kind of magnetic self-adhesive medical electrode slice
CN104615887A (en) * 2015-02-05 2015-05-13 广州市润杰医疗器械有限公司 Voice-image matching method for detecting cognitive function of child
CN207055487U (en) * 2017-02-13 2018-03-02 浙江普可医疗科技有限公司 Disposable wireless encryption eeg sensor
CN106923816A (en) * 2017-03-10 2017-07-07 苏州格林泰克科技有限公司 A kind of biopotential electrode with flexible cable
CN207236786U (en) * 2017-03-10 2018-04-17 武汉格林泰克科技有限公司 Disposable anesthesia depth monitoring sensor
CN207870892U (en) * 2017-09-19 2018-09-18 河南驼人医疗器械集团有限公司 One kind being used for neonatal EEG signals detection device
CN208492091U (en) * 2017-12-13 2019-02-15 浙江普可医疗科技有限公司 Disposable multi-parameter eeg sensor
CN209770365U (en) * 2019-01-25 2019-12-13 中国福利会国际和平妇幼保健院 Disposable neonatal limb lead electrode plate
CN211749604U (en) * 2020-01-21 2020-10-27 苏州小蓝医疗科技有限公司 Novel electroencephalogram signal acquisition implementation device

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