CN111035449B - Ultrasonic laser catheter - Google Patents

Ultrasonic laser catheter Download PDF

Info

Publication number
CN111035449B
CN111035449B CN201811181224.1A CN201811181224A CN111035449B CN 111035449 B CN111035449 B CN 111035449B CN 201811181224 A CN201811181224 A CN 201811181224A CN 111035449 B CN111035449 B CN 111035449B
Authority
CN
China
Prior art keywords
laser
ultrasonic
catheter
radial
fiber layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201811181224.1A
Other languages
Chinese (zh)
Other versions
CN111035449A (en
Inventor
庞兴学
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dongzhimen Hospital Of Beijing University Of Chinese Medicine
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201811181224.1A priority Critical patent/CN111035449B/en
Publication of CN111035449A publication Critical patent/CN111035449A/en
Application granted granted Critical
Publication of CN111035449B publication Critical patent/CN111035449B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0891Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00404Blood vessels other than those in or around the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00589Coagulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2205Characteristics of fibres

Abstract

The invention relates to the field of medical instruments, and provides an ultrasonic laser catheter which comprises a catheter body, wherein the catheter body comprises a head end, a tail end, a catheter wall and a catheter cavity. By the catheter and the realization method, the ablation of the target tissue is implemented under the monitoring of the ultrasonic probe equipment.

Description

Ultrasonic laser catheter
Technical Field
The invention relates to the field of medical instruments, in particular to an ultrasonic laser catheter.
Background
At present, the methods for tissue ablation or tissue removal through blood vessels include:
(1) radiofrequency ablation, necrosis of tissue by the thermal effect of radiofrequency current, temperature control at 37-55 deg.C, which can make tissue coagulation necrosis but not liquefaction and removal.
(2) Microwave ablation, which utilizes high-frequency electromagnetic waves to act on tissues to rapidly generate heat to necrose the tissues, and the temperature of the tissues rises rapidly, so that surrounding tissues are easily damaged.
(3) Rotary cutting the tissue, cutting the tissue by using a high-speed rotary grinding drill or grinding and emulsifying the tissue into micro particles so as to achieve the purpose of tissue ablation.
(4) Tissue rotational grinding, which is a method of grinding a rotating head tissue with ultra-high speed rotation or a calcified tissue into ultrafine particles, is often applied to calcified tissues, and is likely to cause vascular perforation and interlayer when the tissue is removed by rotational grinding.
(5) Laser ablation, during laser ablation tissue, lead to the vascular wall damage easily, like vascular perforation and intermediate layer, excimer laser has reduced the incidence of vascular wall damage because penetration depth can restrict at 50 ~100 microns, but present excimer laser pipe still can not melt the tissue that gets into the lumen.
Chinese patent document CN103747758 describes an ultrasonic laser catheter for bypass surgery and describes a tubular arrangement of optically limited tubular bundles for emitting laser light, in which the optical fibers are arranged in an array of bundle structures. Chinese patent document CN1025148C describes a laser surgical instrument for vascular surgery, and describes a driving and servo device for performing laser surgery in the prior art.
Intravascular indwelling tube and intravascular diagnosis and treatment generally require real-time monitoring to realize guidance, positioning, real-time guidance monitoring, diagnosis and treatment and avoid vessel and tissue organ damage caused by catheters, and the current monitoring method for intravascular indwelling tube or intravascular treatment comprises the following steps:
(1) the vascular catheter is sent to a target position under the fluoroscopy of X-rays and the advanced guidance of a metal guide wire. The method has the disadvantages that the method can be implemented only in a place where X rays are installed and X ray protection is needed;
(2) the method adopts a blind method to insert the catheter, and has the defects that the catheter cannot be remotely inserted, and complications such as heart and blood vessel damage, arrhythmia and the like are easily caused;
(3) the balloon floating catheter is adopted, and the power of blood flow is utilized to guide the catheter to move forward, so that the method has high clinical operation difficulty and risks of blood vessel injury and arrhythmia;
there is no catheter or similar product available on the market that can achieve simultaneous monitoring and ablation.
Disclosure of Invention
The technical problem to be solved by the present invention is to provide an ultrasonic laser catheter, which solves the above technical defects, and combines the ultrasonic detection technology, the laser ablation technology and the catheter function to provide a new device. The ultrasonic laser catheter combines the functions of a vascular catheter, an ultrasonic catheter and a laser catheter, so that the ultrasonic laser catheter has the functions of guiding the catheter, ultrasonic detection and laser ablation catheter at the same time, can realize ultrasonic visual guidance when the catheter is placed along a blood vessel, realize synchronous monitoring guidance when monitoring and taking materials through the vascular catheter, and can realize laser ablation of target tissues while ultrasonic detection is carried out.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows: an ultrasonic laser catheter comprises a catheter body, wherein the catheter body comprises a head end, a tail end, a catheter wall and a catheter cavity, first ultrasonic probe equipment for transmitting and receiving ultrasonic beams along the longitudinal axis direction of an ultrasonic laser catheter main body is arranged in the catheter wall, and the first ultrasonic probe equipment is used for detecting information in front of the head end of the ultrasonic laser catheter; the tube wall is also internally provided with a radial laser fiber layer which radially emits laser along the cross section of the main body of the ultrasonic laser catheter, after the radial laser fiber layer extends to a preset distance from the head end of the catheter along the tube wall, an optical fiber bend, an optical fiber side hole, a total reflection device, a reflector, a reflective film pipeline, a total reflection device pipeline or a reflector pipeline is arranged, or the components are combined to change the direction of the laser and then emit radial laser to the tube cavity, and the radial laser ablates tissues entering the tube cavity. The preset distance can be more than or equal to zero millimeters, and the width of the optical fiber side hole is set to be 1-1000 micrometers.
The invention provides an ultrasonic laser catheter, which is characterized in that ultrasonic probe equipment arranged in the wall of a catheter detects blood vessel information in front of the head end of the catheter; and the radial laser fiber layer arranged in the tube wall radially emits laser along the cross section of the ultrasonic laser catheter to ablate tissues in the tube cavity. The ultrasonic laser catheter has the functions of guiding the catheter, ultrasonic detection and laser ablation of the catheter, can realize ultrasonic visual guidance when the catheter is placed along a blood vessel, realize monitoring of the catheter through the blood vessel and synchronous monitoring guidance when materials are taken, and can realize laser ablation of target tissues when ultrasonic detection is carried out.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic perspective view of the present invention.
FIG. 2 is a partial cross-sectional view of a preferred embodiment of the present invention, showing the bending of an optical fiber.
FIG. 3 is a partial cross-sectional view of a fiber side hole according to another preferred embodiment of the present invention.
Fig. 4 is a partial cross-sectional schematic view of a total reflection device according to another preferred embodiment of the present invention.
Fig. 5 is a partial cross-sectional schematic view of another total reflection device according to another preferred embodiment of the present invention.
Fig. 6 is a partial cross-sectional view schematically showing a reflector according to another preferred embodiment of the present invention.
Fig. 7 is a partial sectional view schematically showing a reflection film according to another preferred embodiment of the present invention.
FIG. 8 is a schematic partial cross-sectional view of a reflective film tube according to another preferred embodiment of the present invention.
FIG. 9 is a schematic partial cross-sectional view of a total reflection device tube according to another preferred embodiment of the present invention
FIG. 10 is a partial cross-sectional schematic view of another preferred embodiment of the total internal reflection device pipeline of the present invention.
Fig. 11 is a partial cross-sectional view of a mirror tunnel according to another preferred embodiment of the present invention.
Fig. 12 is a partially sectional schematic view of a first ultrasonic probe apparatus according to another preferred embodiment of the present invention.
Fig. 13 is a partially sectional schematic view of a second ultrasonic probe apparatus according to another preferred embodiment of the present invention.
Fig. 14 is a schematic perspective view of an axial laser fiber layer according to another preferred embodiment of the present invention.
Fig. 15 is a schematic perspective view of a radial laser fiber layer according to another preferred embodiment of the present invention.
Fig. 16 is a schematic perspective view of a reflective film tube according to another preferred embodiment of the present invention.
Fig. 17 is a schematic perspective view of a total reflection device tube according to another preferred embodiment of the present invention.
Fig. 18 is a perspective view of a mirror tunnel according to another preferred embodiment of the present invention.
Fig. 19 is a schematic perspective view of embodiment 1 of the present invention.
Fig. 20 is a schematic perspective view of embodiment 2 of the present invention.
Fig. 21 is a schematic perspective view of embodiment 3 of the present invention.
Fig. 22 is a schematic perspective view of embodiment 4 of the present invention.
In the figure: a pipe body-1, a head end-2, a tail end-3, a pipe wall-4, a pipe cavity-5, an optical fiber-6 (wherein, a radial laser optical fiber layer-61 and an axial laser optical fiber layer-62), an optical fiber bending-7, a total reflection device-8, a reflector-9, a reflection film-10, a reflection film pipeline-11, a total reflection device pipeline-12, a reflector pipeline-13, a narrow gap-14, a laser emission device-15 (wherein, a first unit-151 and a second unit-152 of the laser emission device), an ultrasonic probe device-16 (wherein, a first ultrasonic probe device-161 and a second ultrasonic probe device-162), a transmission line-17, an ultrasonic host-18, an information display screen-19, a light source, a, Ultrasonic beam-20 (wherein: axial ultrasonic beam-201, radial ultrasonic beam-202), laser beam-21 (wherein: axial laser beam-211, radial laser beam-212), fiber side hole-22.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
as shown in fig. 1 and 19, an ultrasonic laser catheter comprises a tube body 1, wherein the tube body 1 comprises a head end 2, a tail end 3, a tube wall 4 and a tube cavity 5. As shown in fig. 12, a first ultrasonic probe device 161 that transmits and receives an ultrasonic beam in the longitudinal axis direction of the ultrasonic laser catheter main body 1 is provided in the tube wall 4 of the ultrasonic laser catheter, and the first ultrasonic probe device 161 transmits an axial ultrasonic beam 201 to detect structural information in front of the head end 2 of the tube body 1. As shown in fig. 15, a radial laser fiber layer 61 is disposed in the tube wall 4 of the ultrasonic laser catheter, and after the radial laser fiber layer 61 extends to a preset distance from the catheter tip along the tube wall 4, a radial laser beam 212 is emitted to the lumen 5 of the ultrasonic laser catheter.
Inside the wall 4 of the ultrasound laser catheter, a first ultrasound probe device 161 is located outside the radial laser fiber layer 61.
Further preferably, in the pipe wall 4 of the ultrasonic laser catheter, the first ultrasonic probe devices 161 and the radial laser fiber layer 61 are arranged at intervals in a ring shape on the same layer.
When the ultrasonic laser catheter is used, the head end of the catheter main body 1 is placed in a target blood vessel, the first ultrasonic probe device 161 collects blood vessel information in front of the head end of the catheter main body 1, feeds the blood vessel information back to the ultrasonic host 18, and displays the information on the screen of the ultrasonic host after the blood vessel information is processed by the ultrasonic host.
The other end of the radial laser fiber layer 61 is connected to the first unit 151 in the laser transmitter 15. The operator activates the first unit 151 of the laser emitting device according to the information of the target ablated tissue in the blood vessel obtained by the ultrasound, and performs ablation on the tissue entering the lumen 5 by selecting different laser sources with different properties or different types and required laser parameters including the frequency, wavelength and energy density of the laser as required.
The tail end of the tube body 1 is provided with an external interface, so that the tube cavity 5 is connected with external equipment, and negative pressure can be applied or other instruments can be conveyed.
The laser generator and the ultrasonic host are arranged into an integrated device.
Example 2:
on the basis of the embodiment 1, as shown in fig. 1, 12 and 20, a first ultrasonic probe device 161 for emitting and receiving ultrasonic beams along the longitudinal axis direction of the ultrasonic laser catheter main body 1 is arranged in the tube wall 4 of the ultrasonic laser catheter, and the first ultrasonic probe device 161 emits an axial ultrasonic beam 201 to detect structural information in front of the head end 2 of the tube body 1. As shown in fig. 13 and 20, a second ultrasonic probe device 162 for emitting and receiving ultrasonic beams outward along the cross section of the ultrasonic laser catheter main body 1 is provided in the tube wall 4 of the ultrasonic laser catheter, and the second ultrasonic probe device 162 emits a radial ultrasonic beam 202 for detecting information on the outer periphery of the head end 2 of the tube body 1. As shown in fig. 15 and 20, a radial laser fiber layer 61 is disposed in the tube wall 4 of the ultrasonic laser catheter, and after the radial laser fiber layer 61 extends to a preset distance from the catheter tip along the tube wall 4, a radial laser beam 212 is emitted to the lumen 5 of the ultrasonic laser catheter.
The second ultrasonic probe device 162, the first ultrasonic probe device 161 and the radial laser fiber layer 61 are sequentially arranged in the pipe wall 4 of the ultrasonic laser catheter from outside to inside.
Further preferably, the second ultrasonic probe device 162 and the first ultrasonic probe device 161 are arranged in sequence from outside to inside in the pipe wall 4 of the ultrasonic laser catheter. The radial laser fiber layer 61 and the second ultrasonic probe device 162 are arranged at intervals in a ring shape on the same layer; or the radial laser fiber layers 61 and the first ultrasonic probe device 161 are arranged at intervals in a ring shape on the same layer.
When the ultrasonic laser catheter is used, the head end of the catheter main body 1 is placed in a target blood vessel, the first ultrasonic probe device 161 collects blood vessel information in front of the head end of the catheter main body 1, feeds the blood vessel information back to the ultrasonic host 18, and displays the information on the screen of the ultrasonic host after the blood vessel information is processed by the ultrasonic host. The second ultrasonic probe device 162 receives the structure and distance information of the peripheral vascular wall 4 at the head end of the catheter main body 1 and the structure and distance information of the extravascular organ tissues, feeds the information back to the ultrasonic host 18, processes the information by the ultrasonic host, and displays the information on the screen of the ultrasonic host.
The other end of the radial laser fiber layer 61 for radially emitting laser is connected with the first unit 151 in the laser emitting device 15;
the operator activates the first unit 151 of the laser emitting device 15 according to the information of the target ablated tissue in the blood vessel obtained by the ultrasound, and performs ablation of the tissue in the catheter lumen 5 by selecting different properties or different types of laser sources and required laser parameters including frequency, wavelength and energy density of the laser as required.
The tail end of the tube body 1 is provided with an external interface, so that the tube cavity 5 is connected with external equipment, and negative pressure can be applied or other instruments can be conveyed.
The laser generator and the ultrasonic host are arranged into an integrated device.
Example 3:
on the basis of the embodiment 1, as shown in fig. 1, 12 and 21, a first ultrasonic probe device 161 for emitting and receiving ultrasonic beams along the longitudinal axis direction of the ultrasonic laser catheter main body 1 is arranged in the tube wall 4 of the ultrasonic laser catheter, the first ultrasonic probe device 161 emits an axial ultrasonic beam 201, and structural information in front of the head end 2 of the tube body 1 is detected; as shown in fig. 14, an axial laser fiber layer 62 for emitting laser light along the longitudinal axis direction of the ultrasonic laser catheter body 1 is disposed in the tube wall 4 of the ultrasonic laser catheter, and the axial laser fiber layer 62 emits an axial laser beam 211 along the longitudinal axis direction of the ultrasonic laser catheter; as shown in fig. 15, a radial laser fiber layer 61 is disposed in the tube wall 4 of the ultrasonic laser catheter, and after the radial laser fiber layer 61 extends to a preset distance from the catheter head end along the tube wall 4, a radial laser beam 212 is emitted to the lumen 5 of the ultrasonic laser catheter.
The first ultrasonic probe device 161, the axial laser fiber layer 62 and the radial laser fiber layer 61 are sequentially arranged in the pipe wall 4 of the ultrasonic laser catheter from outside to inside.
When the ultrasonic laser catheter is used, the head end of the catheter main body 1 is placed in a target blood vessel, the first ultrasonic probe device 161 collects blood vessel information in front of the head end of the catheter main body 1, feeds the blood vessel information back to the ultrasonic host 18, and displays the information on the screen of the ultrasonic host after the blood vessel information is processed by the ultrasonic host.
The other end of the axial laser fiber layer 62 for axially emitting laser is connected with the second unit 152 in the laser emitting device 15;
the other end of the radial laser fiber layer 61 for radially emitting laser is connected with the first unit 151 in the laser emitting device 15;
the operator activates the first unit 151 and the second unit 152 of the laser emitting device 15 according to the information of the target ablation tissue in the blood vessel obtained by the ultrasound, and selects different laser sources with different properties or different types and required laser parameters including the frequency, the wavelength and the energy density of the laser according to the requirements, so as to perform the ablation on the tissue in the lumen 5 and in front of the head end of the ultrasonic laser catheter simultaneously.
The tail end of the tube body 1 is provided with an external interface, so that the tube cavity 5 is connected with external equipment, and negative pressure can be applied or other instruments can be conveyed.
Example 4:
on the basis of the embodiment 1, as shown in fig. 1, 12 to 15 and 22, a second ultrasonic probe device 162 for emitting and receiving ultrasonic beams outwards along the cross section of the ultrasonic laser catheter main body 1 is arranged in the tube wall 4 of the ultrasonic laser catheter, and detects information on the periphery of the head end 2 of the tube body 1. As shown in fig. 12 and 22, a first ultrasonic probe device 161 which transmits and receives ultrasonic beams along the longitudinal axis direction of the ultrasonic laser catheter main body 1 is arranged in the tube wall 4 of the ultrasonic laser catheter, and structural information in front of the head end 2 of the tube body 1 is detected; as shown in fig. 14 and 22, an axial laser fiber layer 62 for emitting laser light along the longitudinal axis direction of the ultrasonic laser catheter body 1 is arranged in the tube wall 4 of the ultrasonic laser catheter, and the axial laser fiber layer 62 emits an axial laser beam 211 along the longitudinal axis direction of the ultrasonic laser catheter; the tube wall 4 of the ultrasonic laser catheter is internally provided with a radial laser fiber layer 61, and after the radial laser fiber layer 61 extends to a preset distance away from the catheter head end along the tube wall 4, radial laser beams 212 are emitted to the tube cavity 5 of the ultrasonic laser catheter.
The second ultrasonic probe device 162, the first ultrasonic probe device 161, the axial laser fiber layer 62 and the radial laser fiber layer 61 are sequentially arranged in the pipe wall 4 of the ultrasonic laser catheter from outside to inside.
Further, the second ultrasonic probe apparatus 162 and the first ultrasonic probe apparatus 161 are disposed outside within the tube wall 4 of the ultrasonic laser catheter, and the second ultrasonic probe apparatus 162 is located outside the first ultrasonic probe apparatus 161; the axial laser fiber layer 62 and the radial laser fiber layer 61 are on the inner side of the pipe wall 4 of the ultrasonic laser catheter, and the axial laser fiber layer 62 is positioned on the outer side of the radial laser fiber layer 61.
Furthermore, the second ultrasonic probe device 162 and the first ultrasonic probe device 161, the axial laser fiber layer 62 and the radial laser fiber layer 61 are arranged at intervals in a ring shape on the same layer surface in the pipe wall 4 of the ultrasonic laser catheter.
When the ultrasonic laser catheter is used, the head end of the catheter main body 1 is placed in a target blood vessel, the first ultrasonic probe device 161 collects blood vessel information in front of the head end of the catheter main body 1, feeds the blood vessel information back to the ultrasonic host 18, and displays the information on the screen of the ultrasonic host after the blood vessel information is processed by the ultrasonic host. The second ultrasonic probe device 162 receives the structure and distance information of the peripheral vascular wall 4 at the head end of the catheter main body 1 and the structure and distance information of the extravascular organ tissues, feeds the information back to the ultrasonic host 18, processes the information by the ultrasonic host, and displays the information on the screen of the ultrasonic host.
The other end of the axial laser fiber layer 62 for emitting laser in the longitudinal axis direction of the ultrasonic laser catheter is connected with a second unit 152 in the laser emitting device 15;
the other end of the radial laser fiber layer 61 of the ultrasonic laser conduit for radially emitting laser is connected with the first unit 151 in the laser emitting device 15;
the operator activates the first unit 151 and the second unit 152 of the laser emitting device 15 according to the information of the target ablated tissue in the blood vessel obtained by the ultrasound, and selects laser sources of different properties or different types and required laser parameters including frequency, wavelength and energy density of the laser according to the requirements to perform the ablation of the tissue in the catheter lumen 5 and in front of the catheter tip simultaneously.
The tail end of the tube body 1 is provided with an external interface, so that the tube cavity 5 is connected with external equipment, and negative pressure can be applied or other instruments can be conveyed.
The laser generator and the ultrasonic host are arranged into an integrated device.
Of course, in the first ultrasonic probe apparatus 161 and the second ultrasonic probe apparatus 162, in order to realize transmission and reception of the ultrasonic beam, other components are further included, for example: the acoustic lens, the acoustic coupling layer, the acoustic damping block, the piezoelectric chip, the lead and the connecting structure thereof are all in the prior art, and therefore, the description thereof is omitted in the present invention. In addition, the external ultrasound host 10 for analyzing the image obtained by the ultrasound probe also belongs to the prior art, and is not described in detail.
The ultrasonic vascular catheter, in addition to the above structure, forms the basic structure of the tube wall 4, such as the material of the tube wall 4 and the addition of wires or strips in the tube wall 4 for fracture resistance, which belong to the prior art, and therefore, detailed description is omitted in the present invention.
The laser generator in this example is prior art and will not be described in detail.
In the foregoing detailed description, various features are grouped together in a single embodiment for the purpose of streamlining the disclosure. This method of disclosure is not to be interpreted as reflecting an intention that the claimed embodiments of the subject matter require more features than are expressly recited in each claim. Rather, as the following claims reflect, invention lies in less than all features of a single disclosed embodiment. Thus, the following claims are hereby expressly incorporated into the detailed description, with each claim standing on its own as a separate preferred embodiment of the invention.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. To those skilled in the art; various modifications to these embodiments will be readily apparent, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the disclosure. Thus, the present disclosure is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
What has been described above includes examples of one or more embodiments. It is, of course, not possible to describe every conceivable combination of components or methodologies for purposes of describing the aforementioned embodiments, but one of ordinary skill in the art may recognize that many further combinations and permutations of various embodiments are possible. Accordingly, the embodiments described herein are intended to embrace all such alterations, modifications and variations that fall within the scope of the appended claims. Furthermore, to the extent that the term "includes" is used in either the detailed description or the claims, such term is intended to be inclusive in a manner similar to the term "comprising" as "comprising" is interpreted when employed as a transitional word in a claim. Furthermore, any use of the term "or" in the specification of the claims is intended to mean a "non-exclusive or".
It should be understood that the specific order or hierarchy of steps in the processes disclosed is an example of exemplary approaches. Based upon design preferences, it is understood that the specific order or hierarchy of steps in the processes may be rearranged without departing from the scope of the present disclosure. The accompanying method claims present elements of the various steps in a sample order, and are not intended to be limited to the specific order or hierarchy presented.
The above-described embodiments are merely preferred embodiments of the present invention, and should not be construed as limiting the present invention, and features in the embodiments and examples in the present application may be arbitrarily combined with each other without conflict. The protection scope of the present invention is defined by the claims, and includes equivalents of technical features of the claims. I.e., equivalent alterations and modifications within the scope hereof, are also intended to be within the scope of the invention.

Claims (9)

1. The utility model provides an supersound laser catheter, includes body (1), and body (1) includes head end (2), tail end (3), pipe wall (4), lumen (5), characterized by: a first ultrasonic probe device (161) is arranged in the pipe wall (4) of the ultrasonic laser guide pipe, the first ultrasonic probe device (161) transmits and receives ultrasonic waves along the longitudinal axis direction of the guide pipe, and the structure and position information in front of the head end of the ultrasonic laser guide pipe is detected; furthermore, a radial laser fiber layer (61) is arranged in the tube wall (4), and laser is transmitted to the head end (2) of the tube body (1) through the radial laser fiber layer (61), changes the direction into a cross section, and emits radial laser beams (212) to the tube cavity (5) after the cross section is radial, so as to ablate tissues entering the tube cavity of the ultrasonic laser catheter;
the ultrasonic laser catheter is characterized in that a laser fiber (6) is arranged in a catheter wall (4) of the ultrasonic laser catheter, the fiber (6) is arranged into two layers, one layer is a radial laser fiber layer (61), and after the radial laser fiber layer (61) extends to a preset distance away from the catheter head end along the catheter wall (4), the laser changes direction to be radially towards a catheter cavity (5) along the cross section of the catheter body (1);
the radial laser fiber layer (61) is annular;
furthermore, the radial laser fiber layer (61) extends to a position, which is away from the head end (2) of the catheter, of the preset distance through the inside of the pipe wall (4), and a reflector (9) is arranged in the pipe wall (4), wherein the reflector (9) is formed by coating optical glass, metal and silicon carbide materials with metal silver, aluminum, copper, or a compound of silver, aluminum or copper, or the reflector (9) is an optical element which is formed by other optical materials and can realize the function of the reflector, and the reflector (9) is annularly arranged in the pipe wall (4) of the head end (2) of the pipe body (1); the laser transmitted along the axial direction of the tube body (1) through the radial laser fiber layer (61) is reflected by the reflector (9), so that the laser is changed from the axial direction of the tube body (1) to the radial direction and then is emitted to the tube cavity (5);
or, the radial laser fiber layer (61) extends to a pipe wall (4) at a preset distance from the head end (2) of the pipe through the pipe wall (4) and is internally provided with a reflecting film (10), the reflecting film (10) is a crystal structure formed by periodically arranging dielectric materials with different refractive indexes in space, and the crystal structure further forms a film structure which can enable the light rays incident to the film structure to be totally reflected; the reflecting films (10) are sequentially arranged in the pipe wall (4) of the head end (2) of the conduit along the radial direction of the conduit to form an annular structure; the laser transmitted along the axial direction of the tube body (1) through the radial laser fiber layer (61) changes the direction through the reflecting film (10), so that the laser changes the direction from the longitudinal axis direction of the tube body (1) to the cross section direction and then emits to the tube cavity (5);
or, an annular pipeline which is shaped along the radial direction of the pipe body (1) is arranged in the pipe wall (4) of the radial laser fiber layer (61) which extends to the preset distance from the head end (2) of the pipe through the pipe wall (4), the inner wall of the annular pipeline is provided with a reflecting film (10) to form a reflecting film pipeline (11), a narrow gap (14) is arranged in the reflecting film pipeline (11) towards the direction of the pipe cavity (5) and is vertical to the longitudinal axis of the pipe body (1), the width of the narrow gap (14) is set to be 1-1000 micrometers, the radial laser fiber layer (61) transmits laser into the reflecting film pipeline (11), the laser is reflected by the reflecting film (10) in the annular pipeline and is emitted from the narrow gap (14), and finally the laser is emitted to the pipe cavity (5) after being changed into the radial direction along the axial direction of the pipe body (;
a plurality of optical fibers are arranged on the radial laser optical fiber layer (61) which is arranged in the pipe wall (4) and used for transmitting laser and guiding the laser into the reflecting film pipeline (11);
or, the radial laser fiber layer (61) extends to a preset distance away from the head end (2) of the conduit through the inside of the conduit wall (4), an annular pipeline which is shaped along the radial direction of the conduit is arranged in the conduit wall (4), and a total reflection device (8) is arranged on the inner wall of the annular pipeline to form a total reflection device pipeline (12); a narrow gap (14) is arranged in the total reflection device pipeline (12) towards the direction of the pipe cavity (5) and perpendicular to the longitudinal axis of the conduit, the width of the narrow gap (14) is set to be 1-1000 micrometers, laser is reflected by the total reflection device pipeline (12) and then emitted to the pipe cavity (5) through the narrow gap (14), the radial laser optical fiber layer (61) transmits the laser to the total reflection device pipeline (12), the laser is emitted to the pipe cavity (5) through the narrow gap (14) after being totally reflected, and finally the laser is emitted to the pipe cavity (5) after the longitudinal axis direction of the pipe body (1) is changed into the cross section radial direction;
a plurality of optical fibers are arranged in the radial laser optical fiber layer (61) which is arranged in the pipe wall (4) and used for transmitting laser and guiding the laser to enter the total reflection device pipeline (12);
or, an annular pipeline which is shaped along the radial direction of the pipe body (1) is arranged in the pipe wall (4) of the radial laser fiber layer (61) which extends to the preset distance from the head end (2) of the pipe through the pipe wall (4), the inner wall of the annular pipeline is provided with a reflector (9) to form a reflector pipeline (13), a narrow gap (14) is arranged in the reflector pipeline (13) towards the direction of the pipe cavity (5) and is vertical to the longitudinal axis of the pipe, and the width of the narrow gap (14) is set to be 1-1000 microns; the radial laser fiber layer (61) guides laser into the reflector pipeline (13), reflects the laser and emits the laser from the narrow gap (14), and finally the laser is changed from the longitudinal axis direction of the pipe body (1) to the cross section radial direction and then emits the laser to the pipe cavity (5);
a plurality of optical fibers are arranged on the radial laser optical fiber layer (61) which is arranged in the pipe wall (4) and used for transmitting laser and guiding the laser into the reflector pipeline (13);
the preset distance is greater than or equal to zero millimeters.
2. The ultrasonic laser catheter of claim 1, wherein: the second ultrasonic probe device (162) which emits and receives ultrasonic beams outwards on the cross section of the tube body (1) is arranged in the tube wall (4) of the head end (2) of the ultrasonic laser catheter, the second ultrasonic probe device (162) emits radial ultrasonic beams (202), and information of the periphery of the head end (2) of the tube body (1) is detected.
3. The ultrasonic laser catheter of claim 2, wherein: the second ultrasonic probe device (162), the first ultrasonic probe device (161) and the laser fiber (6) are sequentially arranged in the pipe wall (4) of the ultrasonic laser catheter from outside to inside.
4. The ultrasonic laser catheter of claim 1, wherein: an axial laser optical fiber layer (62) is arranged in a pipe wall (4) of the ultrasonic laser pipe, and the axial laser optical fiber layer (62) emits axial laser beams (211) along the longitudinal axis direction of the pipe body (1) to ablate tissues in front of the head end (2) of the ultrasonic laser pipe.
5. The ultrasonic laser catheter of claim 4, wherein: the first ultrasonic probe device (161), the axial laser fiber layer (62) and the radial laser fiber layer (61) are sequentially arranged in the pipe wall (4) of the ultrasonic laser catheter from outside to inside.
6. The ultrasonic laser catheter of claim 1, wherein: a second ultrasonic probe device (162) is further arranged in the pipe wall (4) of the ultrasonic laser catheter, the second ultrasonic probe device (162) transmits and receives ultrasonic waves to the outer side of the pipe body (1) along the radial direction of the cross section of the catheter, and information of the periphery of the head end (2) of the pipe body (1) is detected;
furthermore, a laser fiber (6) is arranged in the tube wall (4), the laser fiber (6) is arranged into two layers, wherein a radial laser fiber layer (61) is arranged in the tube wall (4) of the ultrasonic laser catheter along the tube body (1), the radial laser fiber layer (61) extends to a preset distance away from the head end of the catheter along the tube wall (4), after the radial laser fiber layer changes direction, a radial laser beam (212) is emitted towards the tube cavity (5), and the radial laser beam (212) ablates tissues entering the tube cavity (5); set up in the pipe wall (4) of supersound laser catheter and set up axial laser fiber layer (62) along body (1) pipe wall, axial laser fiber layer (62) are along body (1) axis of ordinates direction transmission axial laser beam (211), and axial laser beam (211) melt the tissue in supersound laser catheter head end (2) the place ahead.
7. The ultrasonic laser catheter of claim 6, wherein: the second ultrasonic probe device (162), the first ultrasonic probe device (161), the axial laser fiber layer (62) and the radial laser fiber layer (61) are sequentially arranged in the pipe wall (4) of the ultrasonic laser catheter from outside to inside.
8. The ultrasonic laser catheter of claim 1, 2, 4 or 6, wherein: the other end of the radial laser fiber layer (61) for radially emitting laser is connected with a first unit (151) in the laser generating device (15); the other end of the axial laser fiber layer (62) for axially emitting laser is connected with a second unit (152) in the laser generating device (15);
the other end of the tube body (1) is connected with a negative pressure suction device.
9. The ultrasonic laser catheter of claim 1, 2, 4 or 6, wherein: the ultrasonic probe equipment (16) is connected with an ultrasonic host device (18) through a transmission line (17), is processed by the ultrasonic host device (18) and then is displayed on an information display screen (19),
wherein the first ultrasonic probe device (161) is connected with the ultrasonic host device (18) through a transmission line (17), and the second ultrasonic probe device (162) is connected with the ultrasonic host device (18) through the transmission line (17);
the other end of the ultrasonic laser catheter tube body (1) is connected with a negative pressure suction device,
the laser generator and the ultrasonic host are arranged into an integrated device.
CN201811181224.1A 2018-10-11 2018-10-11 Ultrasonic laser catheter Active CN111035449B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811181224.1A CN111035449B (en) 2018-10-11 2018-10-11 Ultrasonic laser catheter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811181224.1A CN111035449B (en) 2018-10-11 2018-10-11 Ultrasonic laser catheter

Publications (2)

Publication Number Publication Date
CN111035449A CN111035449A (en) 2020-04-21
CN111035449B true CN111035449B (en) 2021-04-23

Family

ID=70228928

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811181224.1A Active CN111035449B (en) 2018-10-11 2018-10-11 Ultrasonic laser catheter

Country Status (1)

Country Link
CN (1) CN111035449B (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587972A (en) * 1984-07-16 1986-05-13 Morantte Jr Bernardo D Device for diagnostic and therapeutic intravascular intervention
US5746738A (en) * 1996-11-20 1998-05-05 Cleary & Oxford Associates Laser surgical device
CN108564023A (en) * 2018-04-10 2018-09-21 京东方科技集团股份有限公司 Fingerprint identification device and display equipment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090275932A1 (en) * 2008-05-02 2009-11-05 Zelickson Brian D Laser energy devices and methods for soft tissue removal
TWI402054B (en) * 2010-06-08 2013-07-21 Pai Chi Li Imaging probe

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587972A (en) * 1984-07-16 1986-05-13 Morantte Jr Bernardo D Device for diagnostic and therapeutic intravascular intervention
US5746738A (en) * 1996-11-20 1998-05-05 Cleary & Oxford Associates Laser surgical device
CN108564023A (en) * 2018-04-10 2018-09-21 京东方科技集团股份有限公司 Fingerprint identification device and display equipment

Also Published As

Publication number Publication date
CN111035449A (en) 2020-04-21

Similar Documents

Publication Publication Date Title
US20200289202A1 (en) Ablation system
US10980565B2 (en) Method for ablating body tissue
US11013491B2 (en) Method for focused acoustic computed tomography (FACT)
CN101636668B (en) Device and method for ultrasonic imaging and laser ablation
US20100179434A1 (en) Systems and methods for making and using intravascular ultrasound systems with photo-acoustic imaging capabilities
US20100179432A1 (en) Systems and methods for making and using intravascular ultrasound systems with photo-acoustic imaging capabilities
US11284941B2 (en) Laser ablation catheters having expanded distal tip windows for efficient tissue ablation
CN111035449B (en) Ultrasonic laser catheter
WO2011059792A1 (en) Method and apparatus for treatment of cardiac valve insufficiency
CN111035451B (en) Laser catheter
CN111035450B (en) Laser catheter
CN219000555U (en) Holmium laser fiber
CN113180820A (en) Radial laser ablation catheter
AU2016204484A1 (en) Device for ablating body tissue

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20230909

Address after: 100010 No.5 haiyuncang, Dongcheng District, Beijing

Patentee after: DONGZHIMEN HOSPITAL OF BEIJING University OF CHINESE MEDICINE

Address before: No. 5 Hutong, Shipping Warehouse, Dongcheng District, Beijing 100700

Patentee before: Pang Xingxue