CN1110309C - Medicine for treating psoriasis and preparation method thereof - Google Patents
Medicine for treating psoriasis and preparation method thereof Download PDFInfo
- Publication number
- CN1110309C CN1110309C CN00118508A CN00118508A CN1110309C CN 1110309 C CN1110309 C CN 1110309C CN 00118508 A CN00118508 A CN 00118508A CN 00118508 A CN00118508 A CN 00118508A CN 1110309 C CN1110309 C CN 1110309C
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- CN
- China
- Prior art keywords
- gram
- radix
- sophorae flavescentis
- rhizoma rhei
- borneolum syntheticum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000003814 drug Substances 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 229940079593 drug Drugs 0.000 title claims description 4
- 201000004681 Psoriasis Diseases 0.000 title abstract description 9
- 229940100691 oral capsule Drugs 0.000 claims abstract description 12
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 11
- 241000271039 Agkistrodon Species 0.000 claims abstract description 7
- 241001312741 Gekko swinhonis Species 0.000 claims abstract description 7
- 241000237903 Hirudo Species 0.000 claims abstract description 7
- 241000131808 Scolopendra Species 0.000 claims abstract description 7
- 241000522620 Scorpio Species 0.000 claims abstract description 7
- 239000009490 scorpio Substances 0.000 claims abstract description 7
- 239000002775 capsule Substances 0.000 claims abstract description 5
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims abstract description 4
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 4
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 4
- 239000006071 cream Substances 0.000 claims description 9
- 241000237636 Pheretima Species 0.000 claims description 6
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 claims description 6
- 229940070384 ventolin Drugs 0.000 claims description 6
- 230000001185 psoriatic effect Effects 0.000 claims description 4
- 238000010410 dusting Methods 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims description 3
- 239000000796 flavoring agent Substances 0.000 claims description 3
- 235000019634 flavors Nutrition 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000012856 packing Methods 0.000 claims description 3
- 239000002674 ointment Substances 0.000 abstract description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 235000002991 Coptis groenlandica Nutrition 0.000 abstract 1
- 244000247747 Coptis groenlandica Species 0.000 abstract 1
- 241000243684 Lumbricus Species 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 241000219061 Rheum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 10
- 238000011084 recovery Methods 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 3
- 206010040844 Skin exfoliation Diseases 0.000 description 3
- 230000035618 desquamation Effects 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 206010037888 Rash pustular Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000029561 pustule Diseases 0.000 description 2
- 206010040882 skin lesion Diseases 0.000 description 2
- 231100000444 skin lesion Toxicity 0.000 description 2
- 206010025421 Macule Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a medicament for treating psoriasis and a preparation method thereof, belonging to a Chinese medicinal preparation and being divided into external ointment and oral capsules; it is prepared from Gekko Swinhonis, Scorpio, Agkistrodon, Scolopendra, Hirudo, radix Panacis Quinquefolii, stigma croci Sativi, calculus bovis, radix et rhizoma Rhei, Lumbricus, nidus Vespae, periostracum Cicadae, periostracum Serpentis, radix Sophorae Flavescentis, rhizoma Coptidis, indigo naturalis, radix Notoginseng, and Borneolum Syntheticum by making into oral capsule; is prepared from borneol, rhubarb, flavescent sophora root, goldthread root and phellodendron bark. The oral capsule is matched with the external ointment, so that the psoriasis can be effectively treated, and the psoriasis does not relapse after being cured.
Description
The present invention relates to Chinese medicine preparation, especially treat psoriatic medicine and preparation method.
Psoriasis is commonly called as " psoriasis ", is one of " three big skin stubborn diseases ", and it is healed than refractory, and relapse rate is higher; Bring inconvenience on the living conditions for the patient, and cause great stress and human body misery to it.For curing this disease, people have done the various examinations of repaying, and effect all can not be satisfactory, only can antipruritic and relief of symptoms as: multiple medicine, can't effect a radical cure, and painful hard to bear; Western medicine not only the course of treatment long, and side effect is big, easily recurrence.
The object of the present invention is to provide a kind of instant effect, evident in efficacy, can thoroughly effect a radical cure psoriatic pure Chinese medicine medicine and preparation method thereof.
The objective of the invention is so to realize:
Oral capsule of the present invention, filling a prescription is: Gekko Swinhonis 5-10 gram, Pheretima 10-15 gram, Agkistrodon 25-35 gram, Scorpio 5-10 gram, Scolopendra 5-10 gram, Radix Panacis Quinquefolii 10-15 gram, Stigma Croci 5-10 gram, Hirudo 15-20 gram, Calculus Bovis 5-10 gram, refined 10-15 gram, Radix Et Rhizoma Rhei 20-30 gram, Indigo Naturalis 15-25 gram, Periostracum Cicadae 20-35 gram, Periostracum Serpentis 20-40 gram, Radix Sophorae Flavescentis 40-80 gram, Radix Notoginseng 10-20 gram, Borneolum Syntheticum 2-10 gram, the Nidus Vespae 25-40 gram of connecting.
Preparation method: Gekko Swinhonis, Scorpio, Agkistrodon, Scolopendra, Hirudo, Radix Panacis Quinquefolii, Stigma Croci, Calculus Bovis, Radix Et Rhizoma Rhei nine flavor medicines are total to fine ground end; With the dense extractum shape of making of decocting, dried is ground into smalls with Pheretima, Nidus Vespae, Periostracum Cicadae, Periostracum Serpentis, Radix Sophorae Flavescentis; After two kinds of smalls are filtered with dusting cover,, divide the capsule of packing into to make with all the other each medicine mixings.
Auxiliary external-applied ointment of the present invention, filling a prescription is: Borneolum Syntheticum 5-20 gram, Radix Sophorae Flavescentis 120-200 gram, Radix Et Rhizoma Rhei 50-80 gram, Rhizoma Coptidis 50-85 gram, Cortex Phellodendri 85-110 gram, medical ventolin 260-320 gram.
Preparation method: Borneolum Syntheticum, Radix Et Rhizoma Rhei ground altogether be smalls; Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri are fried in shallow oil concentrated extract altogether; Last evenly makes external cream with being in harmonious proportion with medical ventolin.
The present invention does not contain any hormone for pure Chinese medicinal preparation, has no side effect, oral and external combine treatment, instant effect, cure rate height, and have non-relapse after healing, advantage such as raw material is easy to get, and preparation method is simple.
The present invention has following embodiment:
Get Gekko Swinhonis 7 grams, Pheretima 15 grams, Agkistrodon 30 grams, Scorpio 6 grams, Scolopendra 7 grams, Radix Panacis Quinquefolii 10 grams, Stigma Croci 10 grams, Hirudo 15 grams, Calculus Bovis 6 grams, refined company 10 grams, Radix Et Rhizoma Rhei 25 grams, Indigo Naturalis 20 grams, Periostracum Cicadae 25 grams, Periostracum Serpentis 25 grams, Radix Sophorae Flavescentis 65 grams, Radix Notoginseng 12 grams, Borneolum Syntheticum 5 grams, Nidus Vespae 30 grams.
Gekko Swinhonis, Scorpio, Agkistrodon, Scolopendra, Hirudo, Radix Panacis Quinquefolii, Stigma Croci, Calculus Bovis, Radix Et Rhizoma Rhei nine flavor medicines are total to fine ground end; With the dense extractum shape of making of decocting, dried is ground into smalls with Pheretima, Nidus Vespae, Periostracum Cicadae, Periostracum Serpentis, Radix Sophorae Flavescentis; After two kinds of smalls are filtered with dusting cover,, divide the 0.5 gram capsule of packing into, make oral capsule with all the other each medicine mixings.
Get Borneolum Syntheticum 10 grams, Radix Sophorae Flavescentis 120 grams, Radix Et Rhizoma Rhei 70 grams, Rhizoma Coptidis 65 grams, Cortex Phellodendri 85 grams, medical ventolin 270 grams.
Borneolum Syntheticum, Radix Et Rhizoma Rhei ground altogether be smalls; Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri are fried in shallow oil concentrated extract altogether; Last evenly makes external cream with being in harmonious proportion with medical ventolin.
Usage: external cream is applied to the affected part, every day 2-3 time, can not have quantitatively; Oral capsule each 4-6 grain of being grown up, every day 3 times, symptom light patient can fully recover in one to two week, and two to three weeks of serious symptom take effect, the recovery from illness of six to seven weeks.
During the present invention uses, following three model cases are arranged:
Case 1:
The Heilungkiang Heihe City is paid certain, man, 6 years old.Whole body plays pustule, can disappear voluntarily, sends out pustule newer, pruritus pain unbearably, ill October is surplus.Be diagnosed as psoriasis.Oral affair capsule three times on the one, one time two, cooperate external cream to smear affected part one twice-daily.After two days, pruritus obviously alleviates, and recovery from illness after seven days continued oral capsule ten, consolidated curative effect, follows up a case by regular visits to and does not have recurrence.
Case 2:
The Heilungkiang Heihe City, Lin, woman, 16 years old.In year surplus in the of ill ten, be interrupted and treated repeatedly; Skin lesion place macule flushing, a large amount of desquamations, only minority skin is normal; Desquamation is soaked in the scorching hot swelling in affected part, and acute pruritus is worried waking or sleeping.Be diagnosed as psoriasis.Take oral capsule three times on the one, one time five, cooperate external cream to smear affected part one twice-daily, treat a recovery from illness in month, continuation oral capsule ten days is consolidated curative effect, does not have recurrence so far.
Case 3:
The Heilungkiang Heihe City, Yuan, man, 45 years old.Ill 8 years surplus, a large amount of desquamations of skin lesion, breaks, and attaches most importance to lower limb.Be diagnosed as psoriasis.Take oral capsule every day three times, one time six, cooperate external cream to smear affected part one twice-daily, treat a recovery from illness in month, continue oral capsule January, consolidate curative effect, follow up a case by regular visits to nothing and recur.
Claims (2)
1, the psoriatic medicine of a kind of treatment, be oral capsule and external cream, it is characterized in that: this oral capsule is restrained by Gekko Swinhonis 5-10 gram, Pheretima 10-15 gram, Agkistrodon 25-35 gram, Scorpio 5-10 gram, Scolopendra 5-10 gram, Radix Panacis Quinquefolii 10-15 gram, Stigma Croci 5-10 gram, Hirudo 15-20 gram, Calculus Bovis 5-10 gram, the refined 10-15 of company gram, Radix Et Rhizoma Rhei 20-30 gram, Indigo Naturalis 15-25 gram, Periostracum Cicadae 20-35 gram, Periostracum Serpentis 20-40 gram, Radix Sophorae Flavescentis 40-80 gram, Radix Notoginseng 10-20 gram, Borneolum Syntheticum 2-10 gram, Nidus Vespae 25-40; This external cream is restrained by Borneolum Syntheticum 5-20 gram, Radix Sophorae Flavescentis 120-200 gram, Radix Et Rhizoma Rhei 50-80 gram, Rhizoma Coptidis 50-85 gram, Cortex Phellodendri 85-110 gram, medical ventolin 260-320.
2, the preparation method of the medicine of claim 1, it is characterized in that: Gekko Swinhonis, Scorpio, Agkistrodon, Scolopendra, Hirudo, Radix Panacis Quinquefolii, Stigma Croci, Calculus Bovis, Radix Et Rhizoma Rhei nine flavor medicines are total to fine ground end, with Pheretima, Nidus Vespae, Periostracum Cicadae, Periostracum Serpentis, Radix Sophorae Flavescentis with the dense extractum shape of making of decocting, dried, be ground into smalls, after two kinds of smalls were filtered with dusting cover, mixing divided the 0.5 gram capsule of packing into to make; Borneolum Syntheticum, Radix Et Rhizoma Rhei ground altogether be smalls, Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri are fried in shallow oil concentrated extract altogether, last evenly makes external cream with being in harmonious proportion with medical ventolin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00118508A CN1110309C (en) | 2000-06-07 | 2000-06-07 | Medicine for treating psoriasis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00118508A CN1110309C (en) | 2000-06-07 | 2000-06-07 | Medicine for treating psoriasis and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1279078A CN1279078A (en) | 2001-01-10 |
| CN1110309C true CN1110309C (en) | 2003-06-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00118508A Expired - Fee Related CN1110309C (en) | 2000-06-07 | 2000-06-07 | Medicine for treating psoriasis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1110309C (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327863C (en) * | 2003-12-23 | 2007-07-25 | 徐姗 | Chinese medicine for treating acute or purulent otitis media and the preparation thereof |
| CN101966249B (en) * | 2010-10-29 | 2011-09-28 | 赵慧敏 | Bromhidrosis cleaning spraying agent |
| CN103520587A (en) * | 2012-08-31 | 2014-01-22 | 张国辉 | Snake oil ringworm ointment and preparation method |
| CN103202885A (en) * | 2013-03-26 | 2013-07-17 | 成进学 | Medicinal liquor for treating skin disease psoriasis by reinforced nano silver element vitamin |
| CN106074994B (en) * | 2016-07-15 | 2019-10-25 | 山西中医药大学 | A kind of external drug for treating psoriasis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1219409A (en) * | 1997-12-10 | 1999-06-16 | 叶章照 | Traditional Chinese medicine for curing psoriasis |
| CN1237453A (en) * | 1999-04-20 | 1999-12-08 | 朱花兰 | Snake scorpion skin-nourishing capsule |
-
2000
- 2000-06-07 CN CN00118508A patent/CN1110309C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1219409A (en) * | 1997-12-10 | 1999-06-16 | 叶章照 | Traditional Chinese medicine for curing psoriasis |
| CN1237453A (en) * | 1999-04-20 | 1999-12-08 | 朱花兰 | Snake scorpion skin-nourishing capsule |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1279078A (en) | 2001-01-10 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20030604 Termination date: 20160607 |
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| CF01 | Termination of patent right due to non-payment of annual fee |