CN111012881A - 一种治疗糖尿病及其并发症的中药制剂及制备方法 - Google Patents
一种治疗糖尿病及其并发症的中药制剂及制备方法 Download PDFInfo
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- CN111012881A CN111012881A CN201911381144.5A CN201911381144A CN111012881A CN 111012881 A CN111012881 A CN 111012881A CN 201911381144 A CN201911381144 A CN 201911381144A CN 111012881 A CN111012881 A CN 111012881A
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Abstract
本发明公开了一种治疗糖尿病及其并发症的中药制剂及其制备方法,由人参、白术、茯苓、甘草、当归、熟地、川芎、白芍、肉桂、黄芪、等38味纯中药组成。其功能具有(抗菌消炎、清热解毒、平衡阴阳、气血双补、脏腑统调、活血化瘀、增强机体免疫力)之功能。即清热解毒,保肝明目,滋阴降火,润肺止渴,补脾健胃,补肾滋肺,祛邪不忘扶正之功效。以中草药治疗主要作用着重于脏腑功能的调整,是病人的脏腑阴阳、气血功能逐渐恢复正常值,身体的免疫功能和机体代谢功能正常了,才达到诸症彻底治愈之目的。有效率达98%,治愈率90%以上。
Description
技术领域
本发明涉及药物制剂技术领域,具体涉及一种治疗糖尿病及其并发症的中药制剂及制备方法。
背景技术
据WHO统计资料目前全世界糖尿病患者已达4亿多人,而每年还有几千万新的患者加入这个队伍。严重影响了患者的身心健康,给国家及患者家庭带来了严重的经济负担。
据卫生部门统计90%以上的患者都死于并发症。为什么?并发症久治不愈?这就是医学界在诊断和治疗过程中单纯降糖而忽视了并发症的治疗,而造成的弊病。所以才出现久治不愈问题。
早在几千年前我国很多医学巨著对病因病理就有了详细的阐述。《黄帝内经》曰:五脏皆柔弱者善病消瘅。《河间六书》曰:消渴之疾,三焦受病也。《医学心语》中说口渴多饮为上消,多食善饥,大便秘结为中消,尿急尿频,小便如膏,日渐消瘦者为下消,三消之疾皆燥热结聚也。《景岳全书》曰:三消之病三焦受病也。上消者,渴证也,大渴引饮随饮随渴,古云其病在肺。中消者中焦受病也,多食善饥,大便秘结,其病在脾胃。下消者下焦受病也,尿急尿频,小便黄赤,为淋为浊,如膏如脂,面黑耳焦,日渐消瘦,其病在肾。《千金方》曰:消渴之人愈与未愈常思虑有大痈,何者?消渴之人必于大骨节发痈疽而卒,所以戒之在大痈也,急须备痈药而防之。《河间六书》又说:“夫消渴者多变聋盲目疾”。
综上所述,糖尿病并发症是病及多个脏腑全身综合性疾病的总称,凡是血管所到之处它都能插上一脚难以治愈。绝非单纯胰岛细胞不分泌胰岛素的问题而是某脏腑先发病互相感染引起内分泌紊乱而发病。
发明内容
为解决现有技术的问题,本发明提供一种治疗糖尿病及其并发症的中药制剂及制备方法。
本发明的目的通过以下技术方案来实现:一种治疗糖尿病及其并发症的中药制剂,包括以下重量份的原料:双花3~10份、连翘5~10份、黄芩5~10份、黄连3~6份、黄柏3~10份、重楼5~10份、泽泻6~12份、覆盆子5~10份、川楝子10~12份、独角莲3~9份、八角莲3~9 份、人参3~8份、白术6~12份、茯苓10~15份、甘草3~10份、当归10~15份、熟地10~15 份、川芎10~15份、白芍3~10份、肉桂3~10份、黄芪10~20份、丹参10~12份、川牛膝10~15 份、怀山药10~20份、麦冬5~10份、玉竹10~15份、枸杞子8~12份、知母肉10~12份、生地12~15份、玄参15~20份、淫羊藿8~12份、益智仁8~12份、菟丝子8~12份、沙苑子8~12 份、葫芦巴8~12份、葛根10~15份、天花粉10~15份、威灵仙8~10份。所述治疗糖尿病及其并发症的中药制剂共上述38味纯中药组成。
优选的,所述治疗糖尿病及其并发症的中药制剂,包括以下重量份的原料:双花10份、连翘10份、黄芩10份、黄连5份、黄柏10份、重楼10份、泽泻10份、覆盆子9份、川楝子12份、独角莲9份、八角莲9份、人参8份、白术12份、茯苓15份、甘草10份、当归 15份、熟地15份、川芎15份、白芍10份、肉桂10份、黄芪20份、丹参12份、川牛膝15 份、怀山药20份、麦冬10份、玉竹15份、枸杞子12份、知母肉12份、生地15份、玄参 20份、淫羊藿12份、益智仁12份、菟丝子12份、沙苑子12份、葫芦巴12份、葛根15份、天花粉15份、威灵仙10份。
本发明还涉及保护上述的一种治疗糖尿病及其并发症的中药制剂的制备方法,包括如下步骤:
第一步:将组份一共研细粉待用;其中,组分一为:天花粉、葛根、葫芦巴、沙苑子、菟丝子、益智仁、玄参、生地、知母肉、枸杞子、玉竹、麦冬、怀山药、川牛膝、黄芪、白芍、熟地、当归、甘草、茯苓、人参、独角莲、八角莲、重楼,共计24味药。
第二步:将组份二(余药)煎去渣取汁,再将所得药汁浓缩成滴水成珠状,加入第一步所得细粉,搅拌均匀后,制成药丸,烘干。
其中,组份二(余药)为肉桂、双花、连翘、黄芩、黄连、黄柏、川楝子、白术、泽泻、川芎、丹参、淫羊藿、威灵仙,共计14味药。
本发明所述的中药制剂适应下列糖尿病并发症人群:口渴多饮、尿急尿频、多食善饥、大便秘结、高血压、视物迷糊不清、睡眠不好、四肢麻木疼痛、间歇性瘸行,阴部潮湿、性功能低下不能勃起、痈疽、疮疖、心、脑血管等并发症。
有益效果:本发明所述治疗糖尿病及其并发症的中药制剂由人参、白术、茯苓、甘草、当归、熟地、川芎、白芍、肉桂、黄芪等38味纯中药组成。其具有抗菌消炎、清热解毒、平衡阴阳、气血双补、脏腑统调、活血化瘀、增强机体免疫力之功能,即清热解毒,保肝明目,滋阴降火,润肺止渴,补脾健胃,补肾滋肺,祛邪不忘扶正之功效。以中草药治疗主要作用着重于脏腑功能的调整,是病人的脏腑阴阳、气血功能逐渐恢复正常值,激活胰岛素正常分泌,身体的免疫功能和机体代谢功能正常了,才达到诸症彻底治愈之目的。本发明所述的中药制剂对并发症治愈率90%以上,有效率达98%以上。且制作工艺简单易行。
具体实施方式
下述非限定性实施例可以使本领域的普通技术人员更全面地理解本发明,但不以任何方式限制本发明。
实施例1
一种治疗糖尿病及其并发症的中药制剂,由以下重量份的中药材组成:双花10份、连翘 10份、黄芩10份、黄连5份、黄柏10份、重楼10份、泽泻10份、覆盆子9份、川楝子12 份、独角莲9份、八角莲9份、人参8份、白术12份、茯苓15份、甘草10份、当归15份、熟地15份、川芎15份、白芍10份、肉桂10份、黄芪20份、丹参12份、川牛膝15份、怀山药20份、麦冬10份、玉竹15份、枸杞子12份、知母肉12份、生地15份、玄参20份、淫羊藿12份、益智仁12份、菟丝子12份、沙苑子12份、葫芦巴12份、葛根15份、天花粉15份、威灵仙10份。
上述的治疗糖尿病及其并发症的中药制剂的制备方法,包括如下步骤:
第一步:将组份一共研细粉待用;其中,组分一为:天花粉、葛根、葫芦巴、沙苑子、菟丝子、益智仁、玄参、生地、知母肉、枸杞子、玉竹、麦冬、怀山药、川牛膝、黄芪、白芍、熟地、当归、甘草、茯苓、人参、独角莲、八角莲、重楼,共计24味药。
第二步:将组份二(余药)加水浓煎去渣取汁,再将所得药汁浓缩成滴水成珠状,加入第一步所得细粉,搅拌均匀成面团状,制成药丸,用80℃恒温烘干。其中,组份二(余药)为肉桂、双花、连翘、黄芩、黄连、黄柏、川楝子、白术、泽泻、川芎、丹参、淫羊藿、威灵仙,共计14味药。
实施例2
一种治疗糖尿病及其并发症的中药制剂,由以下重量份的中药材组成:双花8份、连翘 8份、黄芩8份、黄连5份、黄柏8份、重楼8份、泽泻8份、覆盆子7份、川楝子10份、独角莲7份、八角莲7份、人参6份、白术8份、茯苓12份、甘草9份、当归14份、熟地 14份、川芎14份、白芍8份、肉桂8份、黄芪15份、丹参12份、川牛膝13份、怀山药18 份、麦冬8份、玉竹13份、枸杞子10份、知母肉12份、生地14份、玄参18份、淫羊藿 10份、益智仁10份、菟丝子10份、沙苑子10份、葫芦巴10份、葛根15份、天花粉15份、威灵仙10份。
上述的治疗糖尿病及其并发症的中药制剂的制备方法,包括如下步骤:
第一步:将组份一共研细粉待用;其中,组分一为:天花粉、葛根、葫芦巴、沙苑子、菟丝子、益智仁、玄参、生地、知母肉、枸杞子、玉竹、麦冬、怀山药、川牛膝、黄芪、白芍、熟地、当归、甘草、茯苓、人参、独角莲、八角莲、重楼,共计24味药。
第二步:将组份二(余药)加水浓煎去渣取汁,再将所得药汁浓缩成滴水成珠状,加入第一步所得细粉,搅拌均匀成面团状,制成药丸,用80℃恒温烘干。其中,组份二(余药)为肉桂、双花、连翘、黄芩、黄连、黄柏、川楝子、白术、泽泻、川芎、丹参、淫羊藿、威灵仙,共计14味药。
实施例3
一种治疗糖尿病及其并发症的中药制剂,由以下重量份的中药材组成:双花5份、连翘 5份、黄芩6份、黄连6份、黄柏5份、重楼6份、泽泻10份、覆盆子9份、川楝子12份、独角莲5份、八角莲5份、人参5份、白术8份、茯苓10份、甘草5份、当归10份、熟地 10份、川芎12份、白芍5份、肉桂5份、黄芪18份、丹参10份、川牛膝10份、怀山药10 份、麦冬6份、玉竹10份、枸杞子10份、知母肉10份、生地12份、玄参15份、淫羊藿8 份、益智仁10份、菟丝子10份、沙苑子10份、葫芦巴10份、葛根12份、天花粉12份、威灵仙8份。
上述的治疗糖尿病及其并发症的中药制剂的制备方法,包括如下步骤:
第一步:将组份一共研细粉待用;其中,组分一为:天花粉、葛根、葫芦巴、沙苑子、菟丝子、益智仁、玄参、生地、知母肉、枸杞子、玉竹、麦冬、怀山药、川牛膝、黄芪、白芍、熟地、当归、甘草、茯苓、人参、独角莲、八角莲、重楼,共计24味药。
第二步:将组份二(余药)加水浓煎去渣取汁,再将所得药汁浓缩成滴水成珠状,加入第一步所得细粉,搅拌均匀成面团状,制成药丸,用80℃恒温烘干。其中,组份二(余药)为肉桂、双花、连翘、黄芩、黄连、黄柏、川楝子、白术、泽泻、川芎、丹参、淫羊藿、威灵仙,共计14味药。
实施例1所述的治疗糖尿病及其并发症的中药制剂应用的具体案例如下:
(1)徐某,男,50岁,辽宁省丹东市人。病史已五年,口渴多饮,每天喝五暖瓶水还觉渴,尿急尿频,大便秘结,视物模糊不清,下肢麻木疼痛,多食善饥,服用本发明两个疗程,上述症状消失。巩固两个疗程,不但并发症痊愈,血糖由原来的18.3mmoI/L,现恢复到5.8mmoI/L。至今10年未复发。
(2)宋某,男,55岁,辽宁省丹东市人,企业老板。病史10多年,口渴可多饮,尿急尿频,每天尿几十次,大便燥结,四肢麻木疼痛,电脑打字手指触碰键盘象触电一样痛,睡眠不好,整晚上不睡觉,高血压,腰膝酸软走不动道,视物模糊不清,阴部潮湿,性功能低下不能勃起,双脚皲裂怕冷。服用本发明三个月上述并发症消失,巩固三个疗程痊愈,原来血糖20.4mmoI/L,降到5.8mmoI/L,至今13年未复发。
(3)李某,男,54岁,吉林省蛟河市黄松甸镇花园村人,多食善饥,大便秘结,口渴多饮,尿急尿频,浑身疲劳没有劲,腰膝酸软走不动道,视物模糊不清,20米远有人看不见,脖子后长了个三公分大的瘤子,五六年也没治好,之后病情加重,躺在炕上不能干活,医院检查血糖23.5mmoI/L,服用本发明三个月,上述并发症消失,脖子后边是那个瘤子也不见了,大啤酒肚消失,血糖恢复到5.8mmoI/L,至今15年没有复发。去年7月14日糖尿病普查,身体各项指标正常。
(4)张某,50岁,男,吉林省柳河县人。2002年查出糖尿病合并发症,空腹血糖23.6mmoI/L,病史10多年,口渴多饮,尿急尿频,大便秘结,视物模糊不清,高血压,睡眠不好,腰膝酸软走不动道,家住七楼空手上楼要歇息三次才能到家,阴部潮湿,性功能低下不能勃起,大啤酒肚,长期休病假。服用本发明三个月诸症好转,巩固三个疗程痊愈。至今17年没有复发。
(5)李某,男,54岁,吉林省长春人。睡眠不好,牙龈出血,总觉疲劳浑身没有劲,腰膝酸软走道费劲,下肢间歇性瘸行,双脚皲裂,麻木疼痛,下肢发凉怕冷,性功能低下,10 多年不能勃起,服用本发明6个疗程痊愈,随访10年未复发。
(6)王某,男,62岁,吉林省浑南县人,服药后不但诸症痊愈,他原身上皮里肉外长了几十个鸡蛋黄大小的脂肪瘤也全部消失。
对于任何熟悉本领域的技术人员而言,在不脱离本发明技术方案范围情况下,都可利用上述揭示的技术内容对本发明技术方案作出许多可能的变动和修饰,或修改为等同变化的等效实施例。因此,凡是未脱离本发明技术方案的内容,依据本发明的技术实质对以上实施例所做的任何简单修改、等同变化及修饰,均应仍属于本发明技术方案保护的范围内。
Claims (3)
1.一种治疗糖尿病及其并发症的中药制剂,其特征在于,包括以下重量份的原料:双花3~10份、连翘5~10份、黄芩5~10份、黄连3~6份、黄柏3~10份、重楼5~10份、泽泻6~12份、覆盆子5~10份、川楝子10~12份、独角莲3~9份、八角莲3~9份、人参3~8份、白术6~12份、茯苓10~15份、甘草3~10份、当归10~15份、熟地10~15份、川芎10~15份、白芍3~10份、肉桂3~10份、黄芪10~20份、丹参10~12份、川牛膝10~15份、怀山药10~20份、麦冬5~10份、玉竹10~15份、枸杞子8~12份、知母肉10~12份、生地12~15份、玄参15~20份、淫羊藿8~12份、益智仁8~12份、菟丝子8~12份、沙苑子8~12份、葫芦巴8~12份、葛根10~15份、天花粉10~15份、威灵仙8~10份。
2.根据权利要求1所述的治疗糖尿病及其并发症的中药制剂,其特征在于,包括以下重量份的原料:双花10份、连翘10份、黄芩10份、黄连5份、黄柏10份、重楼10份、泽泻10份、覆盆子9份、川楝子12份、独角莲9份、八角莲9份、人参8份、白术12份、茯苓15份、甘草10份、当归15份、熟地15份、川芎15份、白芍10份、肉桂10份、黄芪20份、丹参12份、川牛膝15份、怀山药20份、麦冬10份、玉竹15份、枸杞子12份、知母肉12份、生地15份、玄参20份、淫羊藿12份、益智仁12份、菟丝子12份、沙苑子12份、葫芦巴12份、葛根15份、天花粉15份、威灵仙10份。
3.一种权利要求1或2所述的治疗糖尿病及其并发症的中药制剂的制备方法,其特征在于,步骤如下步骤:
第一步:将组份一共研细粉待用;其中,组分一为:天花粉、葛根、葫芦巴、沙苑子、菟丝子、益智仁、玄参、生地、知母肉、枸杞子、玉竹、麦冬、怀山药、川牛膝、黄芪、白芍、熟地、当归、甘草、茯苓、人参、独角莲、八角莲、重楼;
第二步:将余药煎去渣取汁,再将所得药汁浓缩成滴水成珠状,加入第一步所得细粉,搅拌均匀后,制成药丸,烘干。
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