CN111012329A - High-precision, sports and noninvasive portable heart-lung function parameter measuring equipment - Google Patents

High-precision, sports and noninvasive portable heart-lung function parameter measuring equipment Download PDF

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Publication number
CN111012329A
CN111012329A CN201911282486.1A CN201911282486A CN111012329A CN 111012329 A CN111012329 A CN 111012329A CN 201911282486 A CN201911282486 A CN 201911282486A CN 111012329 A CN111012329 A CN 111012329A
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signal
microcontroller
precision
impedance
module
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CN201911282486.1A
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Chinese (zh)
Inventor
余洪龙
解启莲
宋泽阳
徐小菊
杨东
解尧
李剑
李杨帅
陈宏凯
王昆
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Anhui Tongling Bionic Technology Co Ltd
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Anhui Tongling Bionic Technology Co Ltd
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Priority to CN201911282486.1A priority Critical patent/CN111012329A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

The invention belongs to the technical field of cardiopulmonary function detection, and particularly relates to high-precision, moving and noninvasive portable cardiopulmonary function parameter measuring equipment which comprises an upper computer and a lower computer, wherein the upper computer and the lower computer comprise an electrocardiograph detection module, a chest impedance detection module, a microcontroller and a wireless communication module; the lower computer also comprises an acceleration sensor, the device can accurately detect electrocardiosignals and thoracic impedance signals under the motion state, noise interference caused by motion is greatly reduced, the identification of data characteristic points by an upper computer algorithm is improved, the accuracy of detected data is higher, and the vacancy of non-invasive cardiopulmonary related equipment with cardiopulmonary function at present in China is made up.

Description

High-precision, sports and noninvasive portable heart-lung function parameter measuring equipment
Technical Field
The invention belongs to the technical field of cardiopulmonary function detection, and particularly relates to a high-precision, sports and noninvasive portable cardiopulmonary function parameter measuring device.
Background
Currently, parametric assays reflecting cardiopulmonary function have been used clinically for many years. By monitoring parameters of cardiopulmonary function, which are of great clinical significance to medical and scientific research, we can obtain a lot of valuable parameter information about the patient, such as Heart Rate (HR), chest volume (TFC), rate index (VI), Stroke Volume (SV), heart output volume (CO), etc. With the development of biomedical engineering and clinical medicine, various detection methods of cardiopulmonary function parameters, such as floating catheter technology using thermodilution method, pulse indicator continuous heart rate measurement technology, etc., have appeared, but since these technologies require invasive data detection for patients, not only the technical requirements for medical care personnel are extremely high, but also the detection cost is expensive and the harm to the body of the patient is extremely large, the invasive detection technology has great limitations; meanwhile, noninvasive detection methods are gradually mature, noninvasive detection technologies do not bring physiological harm to patients, detection cost is low, ICG detection parameters of impedance cardiography have great clinical significance, accuracy, reproducibility and sensitivity of the ICG detection parameters can be compared with those of invasive technologies, and more importantly, the ICG detection parameters of impedance cardiography can be used for many special occasions, particularly light patients, critical patients, patients in motion states and the like. However, at present, although a few noninvasive detection devices can be used for light patients and critical patients in China, the detection of the cardiopulmonary function parameters of the patients in the motion state cannot be realized, particularly, the postoperative exercise rehabilitation test of the heart disease patients and the continuous cardiopulmonary function parameter test of athletes cannot be realized, and the problems are perfectly solved by the product. Therefore, it is necessary to further study the operation of the cardiopulmonary function detecting device, improve the accuracy of the detection, and realize the wide application of the exercise cardiopulmonary function detecting device.
Disclosure of Invention
The invention provides a high-precision, sports and noninvasive portable cardiopulmonary function parameter measuring device, which integrates a large number of high-precision and low-power consumption chips into a very small circuit board, can accurately measure various current cardiopulmonary parameters of a human body, increases the portability of the device and greatly prolongs the service life of the device.
In order to achieve the purpose, the invention provides the following technical scheme:
a high-precision, moving and noninvasive portable heart-lung function parameter measuring device comprises an upper computer and a lower computer, wherein the upper computer and the lower computer comprise an electrocardio detection module, a chest impedance detection module, a microcontroller and a wireless communication module, and the chest impedance detection module comprises a signal generator, a filter, a constant current source, an instrument amplifier, a common mode filter, a detection circuit, a high-pass filter, a high-precision signal amplifier, a differential circuit and a voltage lifting module;
the lower computer also comprises a motion state monitoring module, and the motion state monitoring module comprises an acceleration sensor.
Compared with the prior art, the invention has the beneficial effects that:
this device has adopted high accuracy current source, accurate amplifier circuit and impedance calibration system, has reduced the detection error of impedance to the at utmost, has emphatically optimized the signal under the motion state moreover, and under the human body was in the motion state, the signal characteristic point was obvious, greatly increased the host computer to the reduction degree of motion cardiopulmonary signal. The whole device has ultra-low power consumption configuration, the lithium battery meets the operation power consumption of the whole system, and the endurance time can reach 5 days;
the acceleration detection module can monitor the motion state of a human body, the high-noise motion electrocardiosignals detected by the electrocardio detection module are subjected to data compensation by the accelerometer and are stabilized in a certain range, and then the motion impedance data are calibrated by the motion electrocardio data, so that the motion analysis with higher precision is realized;
the device adopts an advanced high-precision low-noise exercise cardiopulmonary measuring circuit, ensures that electrocardiosignals and thoracic impedance signals can be accurately detected under the exercise state, greatly reduces noise interference generated due to exercise, improves the identification of data characteristic points by an upper computer algorithm, and ensures higher accuracy of detected data. Makes up for the vacancy that no noninvasive cardiopulmonary related equipment for moving cardiopulmonary function is available at present in China, and has very high clinical and scientific research significance.
Drawings
FIG. 1 is an overall schematic view provided by the present invention;
FIG. 2 is a schematic block diagram of the present invention;
the reference numbers in the figures illustrate: the system comprises a signal generator 1, a filter 2, a constant current source 3, an instrument amplifier 4, a common mode filter 5, a detection circuit 6, a high pass filter 7, a high precision signal amplification circuit 8, a differential circuit 9, a voltage lifting module 10, an acceleration sensor 11, an electrocardiosensor 12, a power frequency filter 13, a microcontroller 14, a Bluetooth module 15, an upper computer 16 and a lower computer 17.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further explained below by combining the specific drawings.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Example 1
Referring to fig. 1-2, a high-precision, moving and noninvasive portable cardiopulmonary function parameter measuring device includes an upper computer 16 and a lower computer 17, including the upper computer 16 and the lower computer 17, the lower computer 17 includes an electrocardiograph detection module, a thoracic impedance detection module, a microcontroller 14 and a wireless communication module, the thoracic impedance detection module includes a signal generator 1, a filter 2, a constant current source 3, an instrumentation amplifier 4, a common mode filter 5, a detection circuit 6, a high pass filter 7, a high-precision signal amplifier 8, a differentiating circuit 9 and a voltage boosting module 10, the microcontroller 14 controls the signal generator 1 to generate a sine wave, the sine wave passes through the filter 2 and is input to the constant current source 3, a sine wave constant current excitation signal is applied to a human body by a driving shielding lead wire, the instrumentation amplifier 4 detects a signal changing on the human body, the instrumentation amplifier 4 converts the sine wave into a single-ended signal, the common mode filter 5 filters out an electrocardiograph interference signal from the signal, the pure ICG signal enters the detection circuit 6, a signal output by the detection circuit 6 is a basic impedance signal 0 of the human body, outputs a signal to the microcontroller 14, the microcontroller 5 outputs a differential signal which passes through the impedance detection module 368, the high-precision impedance detection circuit 19 outputs a voltage rising signal, the high-precision signal output by the high pass through the impedance detection module 368, the high pass through the impedance detection circuit 638, the high-precision signal output module and the high-precision signal output module 368, and the high-precision signal output module 56, the high-precision signal output module 368;
the lower computer 17 further comprises a motion state monitoring module, and the motion state monitoring module comprises an acceleration sensor 11.
The chest impedance measuring circuit uses a novel DDS chip as a signal generator, sends out a high-frequency sine wave signal, acts on a part to be measured of a human body after passing through a filter circuit and a constant current source circuit, samples the signal by an instrumentation amplifier, and then sends the signal into a micro controller after passing through detection and amplification, and the micro controller obtains a real-time impedance change value after simply calculating a calibration value of a precision resistor.
An electrocardiogram detection circuit with a motion artifact elimination function is used for detecting electrocardiogram signals in motion of a patient. The electrocardio detection circuit is internally provided with a bipolar point low-pass filter with the cutoff frequency of 37Hz and a bipolar point high-pass filter with the cutoff frequency of 0.3Hz, the total signal gain in a pass band is 400, and weak electrocardiosignals collected on a human body flow into the microcontroller module after being completely conditioned by the circuit.
A motion state monitoring circuit, the accelerometer signal monitored can further reduce the noise generated by the motion of the patient; meanwhile, the microcontroller can judge the current motion state of the patient by utilizing the currently monitored motion information, so as to perform corresponding mode conversion.
Further, an LED display module is further arranged on the lower computer and comprises a red LED, a green LED, a blue LED, a white LED and a yellow LED, the red LED represents the charging state, the green LED represents the full-charged state of the battery, the blue LED represents the heart beating state, the white LED represents the running state of the system, and the yellow LED represents the current mode of the system.
Further, the electrocardiosignal on the human body is detected by the electrocardio detection circuit through an electrocardio three-lead line, and the electrocardiosignal which is completely conditioned by the electrocardio detection circuit flows to the microcontroller 14 after passing through the power frequency filter circuit 13.
Furthermore, the chest impedance detection module is used for detecting uV-level human body electric signals from a human body, and after the uV-level human body electric signals pass through the instrument amplifier circuit and the high-precision signal amplification circuit, the amplitude of the uV-level human body electric signals is increased to V level, and the uV-level human body electric signals are collected by the microcontroller and then are sent to the upper computer for analysis.
Further, a buzzer is arranged in the lower computer 17 and electrically connected with the microcontroller 14.
When the battery power is too low or the human body state is detected to be abnormal, the buzzer can give out an alarm for reminding.
Further, the wireless communication module adopts a bluetooth module 15 for transmission, and a data storage module is further arranged in the wireless communication module, and the data storage module is connected with the microcontroller 14.
When no matched Bluetooth signal exists, the MCU stores the detected data into the data storage module, and after the Bluetooth communication is recovered, the stored data is uploaded to the upper computer, so that the effect of uninterrupted detection is achieved.
Further, the amplification factor of the instrument amplifier circuit is adjustable, and the adjustment range is as follows: 1. 2, 5 and 10, the microcontroller can automatically adjust the amplification factor according to the current movement impedance signal, and ensure that the signal is not cut off due to overlarge.
Furthermore, the signal generator is AD9833 in model, the filter is AD8626 in model, the constant current source is AD8625 in model, the instrumentation amplifier is AD8250 in model, the common mode filter is AD8627 in model, the high pass filter is AD8625 in model, the high-precision signal amplifying circuit is AD620 in model, the differential circuit is AD8625 in model, the acceleration sensor is MPU6050 in model, the electrocardio sensor is AD8232 in model, and the microcontroller is STM32 in model,
Note that: the AD8625, the AD8626 and the AD8627 are operational amplifiers of the same type, namely AD8250 operational amplifier, AD8626 operational amplifier and AD9833 operational amplifier.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (10)

1. The utility model provides a high accuracy, sports type, noninvasive portable cardiopulmonary function parameter measurement equipment, includes host computer and host computer, its characterized in that: the chest impedance detection module comprises a signal generator, a filter, a high-precision constant current source, an instrument amplifier, a common mode filter, a detection circuit, a high-pass filter, a high-precision signal amplifier, a differential circuit and a voltage lifting module, the motion state monitoring module is further arranged in the lower computer and comprises an acceleration sensor.
2. The high-precision, moving and noninvasive portable cardiorespiratory function parameter measuring device of claim 1, wherein the microcontroller controls the signal generator to generate sine waves, the sine waves are input to the high-precision constant current source after passing through the filter, the sine wave constant current excitation signal is applied to the human body by the drive shielding lead wire, the instrumentation amplifier detects the signal changed on the human body and converts the signal into a single-ended signal, the common mode filter filters out the electrocardio interference signal from the single-ended signal, the remaining pure ICG signal enters the detection circuit, the signal output by the detection circuit is the human body basic impedance Z0 and is output to the microcontroller, the signal output by the detection circuit passes through the high-pass filter and the high-precision signal amplifier in sequence, the signal output by the high-precision signal amplifier is the impedance change signal △ Z, the high-precision signal amplifier outputs the impedance change signal △ Z to the microcontroller, the impedance change signal △ Z passes through the differential circuit and the voltage raising module in sequence, the voltage raising module outputs the impedance change signal dz to the microcontroller.
3. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: the wireless communication module adopts Bluetooth transmission, and is also internally provided with a data storage module which is connected with the microcontroller.
4. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: and the acceleration sensor signal is connected with the microcontroller.
5. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: the common mode filter can switch a signal output channel, a precision resistor is arranged in the common mode filter, the common mode filter outputs a signal to the precision resistor, the microcontroller collects the signal passing through the precision resistor, and the microcontroller calibrates current impedance data.
6. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: the amplification factor of the instrument amplifier circuit is adjustable, and the adjustment range is as follows: 1. 2, 5 and 10, the microcontroller can automatically adjust the amplification factor according to the current movement impedance signal.
7. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: the electrocardio detection module and the thoracic impedance detection module collect weak signals of electrocardio and thoracic impedance of a human body and transmit the weak signals to the microcontroller for processing, the wireless communication module sends the signals processed by the microcontroller to the upper computer for receiving, and software in the upper computer performs real-time analysis calculation and signal filtering processing on data, synchronously displays waveforms of electrocardio, cardiac impedance and impedance differential, extracts characteristic points of the waveforms by combining an algorithm, and calculates Cardiac Output (CO), pulse rate (SV) and cardiac function index (CI).
8. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: the lower computer is further provided with an LED display module, the LED display module comprises a red LED, a green LED, a blue LED, a white LED and a yellow LED, the red LED represents the charging state, the green LED represents the full-charged state of the battery, the blue LED represents the heart beating state, the white LED represents the running state of the system, and the yellow LED represents the current mode of the system.
9. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: still include power module in the next built-in, power module adopts the lithium cell power supply, lithium cell and microcontroller electric connection.
10. The high accuracy, athletic, non-invasive portable cardiorespiratory function parameter measuring apparatus of claim 1, wherein: and a buzzer is arranged in the lower computer and electrically connected with the microcontroller.
CN201911282486.1A 2019-12-13 2019-12-13 High-precision, sports and noninvasive portable heart-lung function parameter measuring equipment Pending CN111012329A (en)

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CN201911282486.1A CN111012329A (en) 2019-12-13 2019-12-13 High-precision, sports and noninvasive portable heart-lung function parameter measuring equipment

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CN201911282486.1A CN111012329A (en) 2019-12-13 2019-12-13 High-precision, sports and noninvasive portable heart-lung function parameter measuring equipment

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113288103A (en) * 2021-04-01 2021-08-24 安徽通灵仿生科技有限公司 Non-invasive cardiac output monitoring system and method
CN113440347A (en) * 2021-01-11 2021-09-28 宁波市第九医院 Electric standing bed integrating non-contact cardiopulmonary function real-time monitoring and assessment
WO2022068677A1 (en) * 2020-09-29 2022-04-07 上海交通大学 Pulmonary exercise function measurement system based on thoracic impedance

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022068677A1 (en) * 2020-09-29 2022-04-07 上海交通大学 Pulmonary exercise function measurement system based on thoracic impedance
CN113440347A (en) * 2021-01-11 2021-09-28 宁波市第九医院 Electric standing bed integrating non-contact cardiopulmonary function real-time monitoring and assessment
CN113288103A (en) * 2021-04-01 2021-08-24 安徽通灵仿生科技有限公司 Non-invasive cardiac output monitoring system and method

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