CN111000652B - Experimental mouse rapid fixing device and using method thereof - Google Patents
Experimental mouse rapid fixing device and using method thereof Download PDFInfo
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- CN111000652B CN111000652B CN201911345340.7A CN201911345340A CN111000652B CN 111000652 B CN111000652 B CN 111000652B CN 201911345340 A CN201911345340 A CN 201911345340A CN 111000652 B CN111000652 B CN 111000652B
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- mouse
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- movable sleeve
- fixed
- fixed sleeve
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
Abstract
The invention relates to a rapid fixing device for an experimental mouse and a using method thereof, and the rapid fixing device comprises a bottom plate, a fixed sleeve, a movable sleeve and a locking mechanism, wherein the fixed sleeve and the movable sleeve are both of hollow cylindrical structures, the fixed sleeve is arranged on the bottom plate through a support frame, the movable sleeve is coaxially arranged with the fixed sleeve and is rotatably connected with the fixed sleeve, the fixed sleeve and the movable sleeve are provided with a top sliding chute penetrating through the side walls of the fixed sleeve and the movable sleeve and a bottom sliding chute arranged on the inner walls of the fixed sleeve and the movable sleeve, the side wall of the movable sleeve is provided with an operation hole, and the locking mechanism comprises a sliding block, an elastic rack, a screw and an outer ring. The invention is used for quickly fixing the mouse in the animal experiment, can effectively prevent the mouse from struggling to cause fixing failure and hurt experimental personnel, and avoids causing the experiment safety problem.
Description
The technical field is as follows:
the invention relates to the technical field of animal experiment equipment, in particular to a rapid fixing device for an experimental mouse and a using method thereof.
Background art:
the mouse is an animal commonly used in medical experiments, some experiments need to fix the mouse and inject or draw blood through the limbs or the abdominal cavity of the mouse, such as subcutaneous tumor inoculation experiments of the mouse, and the biggest obstacle in the experimental operation is that the mouse is not easy to control and the position of a needle is not easy to grasp. The commonly used operation methods at present are: 1. the experimental mouse is anesthetized and then operated, so that the operation is safe and convenient under the anesthetic state of the mouse, and the defects that the anesthetic operation takes a certain time, the experimental result can be influenced, and the mouse can die due to anesthesia. 2. The two persons cooperate to operate, one person holds the mouse by hand, and the other person operates. The advantages that the mouse is not needed to be anesthetized, and the defects that the labor cost is high, and the experimenter is easy to be bitten by the mouse or pricked by a needle.
Patent No. ZL 201720227329.0's patent is through passing through the support with the sleeve pipe and suspending in the base plate top, the sleeve pipe can carry out 360 degrees rotations, and can stop in the optional position, sheathed tube top and bottom all are equipped with the inoculation window, can cooperate the sleeve pipe after the rotation to inoculate on the optional position, and adjustable concatenation apron has been designed on the sleeve pipe, can be by the size of the adjustable sleeve pipe bore of adjusting screw, the sleeve pipe can change the open mouth size of sleeve pipe according to the mouse volume size of difference, can effectively improve inoculation efficiency. However, the existing fixing device structure needs the mouse to be drilled into the casing according to the life habit of the mouse to fix the mouse, the mouse is unreliable, the mouse can possibly return in the casing or quickly climb out of the casing, a laboratory technician cannot fix the mouse quickly, and the laboratory technician can be scratched or bitten by the mouse in the process of grabbing the mouse and placing the mouse into the casing, so that potential safety hazards exist.
The invention content is as follows:
technical problem to be solved
The invention aims to provide a quick fixing device for an experimental mouse and a using method thereof, which are used for fixing the experimental mouse in experimental operation and solve the problems that the prior art can not quickly fix the mouse, and an experimenter can be scratched or bitten by the mouse in the mouse grabbing process, so that potential safety hazards exist.
The technical scheme is as follows:
in order to solve the technical problems, the invention adopts the following technical scheme: a quick fixing device for experimental mice comprises a bottom plate, a fixing sleeve, a movable sleeve and a locking mechanism, wherein the fixing sleeve and the movable sleeve are of hollow cylindrical structures, the fixing sleeve is arranged on the bottom plate through a supporting frame, the movable sleeve is coaxially arranged with the fixing sleeve and is rotatably connected with the fixing sleeve, a top sliding groove penetrating through the side wall of the fixing sleeve and the side wall of the movable sleeve and a bottom sliding groove arranged on the inner wall of the fixing sleeve and the inner wall of the movable sleeve are arranged on the fixing sleeve and the movable sleeve, an operation hole is arranged on the side wall of the movable sleeve, the locking mechanism comprises a sliding block, an elastic rack, a screw rod and an outer ring, a fixing hole and a connecting groove are arranged on the outer ring, the fixing hole is communicated with the connecting groove, the sliding block is arranged in the bottom sliding groove, the outer ring is arranged in the top sliding groove, one end of the elastic rack is fixed on the outer ring, the other end of the elastic rack winds the inner wall of the fixing sleeve for a circle and is inserted into the connecting groove, the screw rod is rotatably fixed in the fixing hole and is matched with the elastic rack, and the sliding block is connected with the elastic rack through a spring.
The mouse body is placed to fixed sleeve with be used for in the movable sleeve, locking mechanism can be along top spout with the bottom spout is in fixed sleeve with slide in the movable sleeve, the elasticity rack can be along with the rotation of screw rod is tightened up and is relaxed to in order to tie up the mouse tightly, the slider with the outer lane is used for right the elasticity rack is fixed a position, the outer lane can along the top spout slides, the slider along the bottom spout slides, the spring along with the elasticity rack tighten up with relax and warp, for the elasticity rack provides the pulling force, the movable sleeve can rotate, so that change the position of handle hole makes things convenient for experimental operation.
Furthermore, the bottom plate is provided with fixing clamps, the fixing clamps are connected with the bottom plate through elastic pull ropes, the positions of the fixing clamps correspond to the operation holes, the four limbs of the mouse can be pulled out of the movable sleeve through the fixing clamps from the operation holes, and the fixing clamps are used for clamping the four limbs of the mouse to fix the mouse, so that the experiment operation is further facilitated.
Furthermore, the operation holes comprise four leg operation holes and a thoracoabdominal operation hole, the number of the fixing clamps is four, the four fixing clamps correspond to the four leg operation holes respectively, the leg operation holes are used for pulling out four limbs of the mouse and fixing the limbs through the fixing clamps, blood drawing or subcutaneous tumor inoculation operation and the like can be conveniently carried out on the four limbs of the mouse, and the thoracoabdominal operation hole is used for carrying out experimental operation on the thoracoabdominal part of the mouse.
Further, fixed sleeve's inner wall is equipped with the draw-in groove, movable sleeve's inner wall is equipped with the snap ring, fixed sleeve with movable sleeve passes through the snap ring with the cooperation of draw-in groove is rotatably connected, movable sleeve can the free rotation, is convenient for adjust the position of handle hole, simultaneously movable sleeve rotates the back, the top spout with the disconnection of bottom spout, locking mechanism can't slide in movable sleeve guarantees that the mouse head is in the fixed sleeve.
Further, the inside of elasticity rack is equipped with the latex filler strip, the mouse health with the contact of latex filler strip guarantees the mouse by security when elasticity rack is tied up tightly, prevents that the mouse from receiving too big pressure and producing the injures and deaths.
Furthermore, a rubber pad is arranged in the connecting groove and used for increasing the pressure between the elastic rack and the connecting groove, and looseness of the elastic rack during use is avoided.
The invention also discloses a use method of the experimental mouse rapid fixing device, which comprises the following steps:
and step 3, horizontally placing the bottom plate, sliding the outer ring along the top sliding groove to enable the locking mechanism to slide into the fixed sleeve, pulling the whole body of a mouse to enter the movable sleeve, and enabling an experimenter to rotate the movable sleeve in the circumferential direction to enable the operation hole to carry out experiments on the position, which is required to be subjected to experiment operation, of the body of the mouse.
And 4, after the experiment operation is finished, the screw rod is rotated reversely, the elastic rack is loosened under the thrust of the screw rod and the tension of the spring, and the mouse climbs out of the fixed sleeve and is placed into the feeding cage.
(III) the beneficial effects are as follows:
compared with the prior art, the invention has the following beneficial effects: (1) the locking mechanisms which can slide along the top sliding groove and the bottom sliding groove are arranged on the fixed sleeve and the movable sleeve, and bind the mouse through the elastic racks which are rotationally tensioned, so that when an experimenter takes the mouse to perform an experiment, the head of the mouse is only required to be lifted by the tail of the mouse and put into the movable sleeve, and the whole body of the mouse is pulled into the fixed sleeve and the movable sleeve after the head of the mouse is bound through the locking mechanisms, so that the action of the mouse in the whole process is controllable, the fixation is rapid, and the experimenter can be effectively prevented from being scratched or bitten by the mouse; (2) the operation hole is formed in the movable sleeve capable of rotating, so that the position of the operation hole can be changed at any time, and convenience is brought to operation of experimenters.
Description of the drawings:
in order to more clearly illustrate the technical solution in the embodiments of the present invention, the drawings required to be used in the embodiments will be briefly described below.
FIG. 1 is a schematic view of the overall structure of a rapid fixing device for laboratory mice according to an embodiment of the present invention;
FIG. 2 is a schematic cross-sectional view of a rapid fixing device for laboratory mice according to an embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view taken along line A-A of the experimental mouse rapid-fixing device according to the embodiment of the present invention;
FIG. 4 is a left side view of the experimental mouse rapid fixture according to the embodiment of the present invention;
in the figure: 1. a base plate; 2. fixing the sleeve; 3. a movable sleeve; 4. a locking mechanism; 41. a slider; 42. An elastic rack; 43. a screw; 44. an outer ring; 45. a fixing hole; 46. connecting grooves; 47. a spring; 5. a support frame; 6. a top chute; 7. a bottom chute; 8. an operation hole; 81. a leg operation hole; 82. a chest and abdomen operation hole; 9. fixing the pliers; 10. an elastic pull rope; 11. a card slot; 12. a snap ring; 13. a latex filler strip; 14. rubber pad
The specific implementation mode is as follows:
the technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
As shown in fig. 1, fig. 2, fig. 3 and fig. 4, the experimental mouse fast fixing device comprises a bottom plate 1, a fixed sleeve 2, a movable sleeve 3 and a locking mechanism 4, wherein the fixed sleeve 2 and the movable sleeve 3 are both hollow cylindrical structures, the fixed sleeve 2 is arranged on the bottom plate 1 through a support frame 5, the movable sleeve 3 is coaxially arranged with the fixed sleeve 2 and rotatably connected with the fixed sleeve 2, the fixed sleeve 2 and the movable sleeve 3 are provided with a top sliding chute 6 penetrating through the side walls of the fixed sleeve 2 and the movable sleeve 3 and a bottom sliding chute 7 arranged on the inner walls of the fixed sleeve 2 and the movable sleeve 3, the side wall of the movable sleeve 3 is provided with an operation hole 8, the locking mechanism 4 comprises a sliding block 41, an elastic rack 42, a screw 43 and an outer ring 44, the outer ring 44 is provided with a fixed hole 45 and a connecting groove 46, the fixed hole 45 and the connecting groove 46 are communicated, the sliding block 41 is arranged in the bottom sliding groove 7, the outer ring 44 is arranged in the top sliding groove 6, one end of the elastic rack 42 is fixed on the outer ring 44, the other end of the elastic rack 42 winds the inner wall of the fixed sleeve 2 for one circle and is inserted into the connecting groove 46, the screw 43 is rotatably fixed in the fixed hole 45 and is matched with the elastic rack 42, and the sliding block 41 is connected with the elastic rack 42 through the spring 47.
Preferably, be equipped with fixed pincers 9 on bottom plate 1, fixed pincers 9 are connected with bottom plate 1 through elasticity stay cord 10, and the position and the handle hole 8 of fixed pincers 9 correspond, and outside the movable sleeve 3 can be pulled out from handle hole 8 to the four limbs of mouse using fixed pincers 9, fixed pincers 9 are used for cliping the four limbs of mouse and fix the mouse, further make things convenient for the experiment operation.
Preferably, the operation holes 8 include four leg operation holes 81 and a thoracoabdominal operation hole 82, the number of the fixing clamps 9 is four, the four fixing clamps correspond to the four leg operation holes 81, the leg operation holes 81 are used for pulling out the limbs of the mouse and fixing the limbs through the fixing clamps 9, so that blood drawing or subcutaneous tumor inoculation operation and the like can be conveniently performed on the limbs of the mouse, and the thoracoabdominal operation hole 82 is used for performing experimental operation on the thoracoabdominal part of the mouse.
Preferably, the inner wall of fixed sleeve 2 is equipped with draw-in groove 11, and the inner wall of activity sleeve 3 is equipped with snap ring 12, and fixed sleeve 2 and activity sleeve 3 pass through snap ring 12 and are connected with draw-in groove 11's cooperation rotatably, and activity sleeve 3 can the free rotation, the position of the adjustment handle hole 8 of being convenient for, and activity sleeve 3 rotates the back simultaneously, and top spout 6 and bottom spout 7 break off, and locking mechanism 4 can't slide in activity sleeve 3, guarantees that the mouse head is in fixed sleeve 2.
Preferably, the latex filler strip 13 is arranged on the inner side of the elastic rack 42, and the body of the mouse is in contact with the latex filler strip 13, so that the safety of the mouse when the mouse is tightly bound by the elastic rack 42 is ensured, and the mouse is prevented from being injured and killed due to excessive pressure.
Preferably, a rubber pad 14 is arranged in the connecting groove 46, and the rubber pad 14 is used for increasing the pressure between the elastic rack 42 and the connecting groove 46, so as to prevent the elastic rack 42 from loosening during use.
The fixed sleeve 2 and the movable sleeve 3 are used for placing the body of a mouse, the locking mechanism 4 can slide in the fixed sleeve 2 and the movable sleeve 3 along the top sliding groove 6 and the bottom sliding groove 7, the elastic rack 42 can be tightened and loosened along with the rotation of the screw 43 so as to tie the mouse tightly, the sliding block 41 and the outer ring 44 are used for positioning the elastic rack 42, the outer ring 44 can slide along the top sliding groove 6, the sliding block 41 slides along the bottom sliding groove 7, the spring 47 deforms along with the tightening and loosening of the elastic rack 42 to provide tension for the elastic rack 42, the movable sleeve 3 can rotate so as to change the position of the operation hole 8 and facilitate experimental operation, the operation hole 8 comprises four leg operation holes 81 and a thoracoabdominal operation hole 82, the four legs of the fixed pliers 9 are respectively corresponding to the four leg operation holes 81, the leg operation holes 81 are used for pulling out the four limbs of the mouse and are fixed by the fixed pliers 9, the operation of blood drawing or subcutaneous tumor inoculation and the like can be conveniently carried out on four limbs of the mouse, and the thoracoabdominal operation hole 82 is used for carrying out experimental operation on the thoracoabdominal part of the mouse.
The application method of the experimental mouse rapid fixing device provided by the embodiment of the invention comprises the following steps:
And 4, after the experiment operation is finished, the screw 43 is rotated reversely, the elastic rack 42 is loosened under the thrust of the screw 43 and the tension of the spring 47, and the mouse climbs out of the fixed sleeve 2 and is placed into the feeding cage.
In conclusion, the rapid fixing device for the experimental mouse and the use method thereof provided by the invention are used for fixing the experimental mouse in the experimental operation, and solve the problems that the prior art cannot fix the mouse rapidly, and a laboratory worker may be scratched or bitten by the mouse in the mouse grabbing process, so that potential safety hazards exist.
The present invention has been described above by way of example, but the present invention is not limited to the above-described specific embodiments, and any modification or variation made based on the present invention is within the scope of the present invention as claimed.
Claims (7)
1. The utility model provides a quick fixing device of laboratory mouse which characterized in that: comprises a bottom plate, a fixed sleeve, a movable sleeve and a locking mechanism, wherein the fixed sleeve and the movable sleeve are both hollow cylindrical structures, the fixed sleeve is arranged on the bottom plate through a support frame, the movable sleeve is coaxially arranged with the fixed sleeve and is rotatably connected with the fixed sleeve, the fixed sleeve and the movable sleeve are provided with a top sliding groove penetrating through the side wall of the fixed sleeve and the movable sleeve and a bottom sliding groove arranged on the inner wall of the fixed sleeve and the movable sleeve, the side wall of the movable sleeve is provided with an operation hole, the locking mechanism comprises a sliding block, an elastic rack, a screw rod and an outer ring, the outer ring is provided with a fixed hole and a connecting groove, the fixed hole is communicated with the connecting groove, the sliding block is arranged in the bottom sliding groove, the outer ring is arranged in the top sliding groove, one end of the elastic rack is fixed on the outer ring, the other end of the elastic rack winds the inner wall of the fixing sleeve for a circle and is inserted into the connecting groove, the screw rod is rotatably fixed in the fixing hole and is matched with the elastic rack, and the sliding block is connected with the elastic rack through a spring.
2. The experimental mouse rapid fixing device according to claim 1, characterized in that: the bottom plate is provided with fixing pliers, the fixing pliers are connected with the bottom plate through elastic pull ropes, and the positions of the fixing pliers correspond to the operating holes.
3. The experimental mouse rapid fixing device according to claim 2, characterized in that: the operation holes comprise four leg operation holes and a thoracoabdominal operation hole, and the number of the fixed clamps is four, and the four fixed clamps correspond to the four leg operation holes respectively.
4. The experimental mouse rapid fixing device according to claim 1, characterized in that: the inner wall of the fixed sleeve is provided with a clamping groove, the inner wall of the movable sleeve is provided with a clamping ring, and the fixed sleeve and the movable sleeve are rotatably connected through the matching of the clamping ring and the clamping groove.
5. The experimental mouse rapid fixing device according to claim 1, characterized in that: and a latex filler strip is arranged on the inner side of the elastic rack.
6. The experimental mouse rapid fixing device according to claim 1, characterized in that: and a rubber pad is arranged in the connecting groove.
7. The use method of the experimental mouse rapid fixing device based on the claim 1 is characterized by comprising the following steps:
step 1, placing the end face of the fixed sleeve vertically downwards, and sliding the outer ring along the top sliding groove to enable the locking mechanism to slide to the end part of the movable sleeve;
step 2, an experimenter grabs the tail of the mouse to lift the mouse upside down, places the mouse into the movable sleeve with the head facing downwards, rotates the screw rod to enable the elastic rack to move in the connecting groove, tightens the elastic rack in the movable sleeve, and wraps and fixes the head of the mouse;
step 3, horizontally placing the bottom plate, sliding the outer ring along the top sliding groove to enable the locking mechanism to slide into the fixed sleeve, enabling the whole body of a mouse to enter the movable sleeve under the pulling of the locking mechanism, and enabling an experimenter to perform an experiment on a position, which is required to perform experiment operation, on the body of the mouse by rotating the movable sleeve in the circumferential direction;
and 4, after the experiment operation is finished, the screw rod is rotated reversely, the elastic rack is loosened under the thrust of the screw rod and the tension of the spring, and the mouse climbs out of the fixed sleeve and is placed into the feeding cage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911345340.7A CN111000652B (en) | 2019-12-24 | 2019-12-24 | Experimental mouse rapid fixing device and using method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911345340.7A CN111000652B (en) | 2019-12-24 | 2019-12-24 | Experimental mouse rapid fixing device and using method thereof |
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| Publication Number | Publication Date |
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| CN111000652A CN111000652A (en) | 2020-04-14 |
| CN111000652B true CN111000652B (en) | 2021-07-30 |
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| CN201911345340.7A Active CN111000652B (en) | 2019-12-24 | 2019-12-24 | Experimental mouse rapid fixing device and using method thereof |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080168948A1 (en) * | 2007-01-11 | 2008-07-17 | Starr Life Sciences Corp. | Small animal restraining device with non-traumatic animal loading device |
| CN207444949U (en) * | 2017-03-20 | 2018-06-05 | 黑龙江中医药大学 | A kind of big mouse blood sampling, administration and execution device |
| JP6814716B2 (en) * | 2017-10-12 | 2021-01-20 | 日本クレア株式会社 | Retention device for laboratory animals |
| CN108245149B (en) * | 2018-01-19 | 2020-11-24 | 成都泰盟软件有限公司 | Mouse tail pulse noninvasive blood pressure rapid measuring device |
| CN209392145U (en) * | 2018-09-12 | 2019-09-17 | 中国医科大学附属盛京医院 | A kind of experiment fixes device with intravital mouse |
| CN209136963U (en) * | 2018-09-27 | 2019-07-23 | 杭州医学院 | A kind of novel mouse fixator |
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