CN110996754B - 用于测定胃排空参数的可吞咽胶囊、系统和方法 - Google Patents

用于测定胃排空参数的可吞咽胶囊、系统和方法 Download PDF

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Publication number
CN110996754B
CN110996754B CN201880052262.9A CN201880052262A CN110996754B CN 110996754 B CN110996754 B CN 110996754B CN 201880052262 A CN201880052262 A CN 201880052262A CN 110996754 B CN110996754 B CN 110996754B
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China
Prior art keywords
capsule
electrode
signal
gastric emptying
small intestine
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Expired - Fee Related
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CN201880052262.9A
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English (en)
Chinese (zh)
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CN110996754A (zh
Inventor
米尔·伊姆兰
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Rani Therapeutics LLC
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Incube Laboratories LLC
Rani Therapeutics LLC
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Priority to CN202310032767.1A priority Critical patent/CN115844361A/zh
Publication of CN110996754A publication Critical patent/CN110996754A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6861—Capsules, e.g. for swallowing or implanting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
    • A61B5/036—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs by means introduced into body tracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/07—Endoradiosondes
    • A61B5/073—Intestinal transmitters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4238—Evaluating particular parts, e.g. particular organs stomach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/162—Capsule shaped sensor housings, e.g. for swallowing or implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0026—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the transmission medium
    • A61B5/0028—Body tissue as transmission medium, i.e. transmission systems where the medium is the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4255—Intestines, colon or appendix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN201880052262.9A 2017-06-12 2018-06-12 用于测定胃排空参数的可吞咽胶囊、系统和方法 Expired - Fee Related CN110996754B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310032767.1A CN115844361A (zh) 2017-06-12 2018-06-12 用于测定胃排空参数的可吞咽胶囊、系统和方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762518246P 2017-06-12 2017-06-12
US62/518,246 2017-06-12
PCT/US2018/037153 WO2018231865A2 (en) 2017-06-12 2018-06-12 Swallowable capsule, system and method for measuring gastric emptying parameters

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202310032767.1A Division CN115844361A (zh) 2017-06-12 2018-06-12 用于测定胃排空参数的可吞咽胶囊、系统和方法

Publications (2)

Publication Number Publication Date
CN110996754A CN110996754A (zh) 2020-04-10
CN110996754B true CN110996754B (zh) 2023-01-31

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CN201880052262.9A Expired - Fee Related CN110996754B (zh) 2017-06-12 2018-06-12 用于测定胃排空参数的可吞咽胶囊、系统和方法
CN202310032767.1A Pending CN115844361A (zh) 2017-06-12 2018-06-12 用于测定胃排空参数的可吞咽胶囊、系统和方法

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Country Link
US (2) US11103187B2 (cg-RX-API-DMAC7.html)
EP (1) EP3638111A4 (cg-RX-API-DMAC7.html)
JP (3) JP7183194B2 (cg-RX-API-DMAC7.html)
CN (2) CN110996754B (cg-RX-API-DMAC7.html)
AU (1) AU2018282907B2 (cg-RX-API-DMAC7.html)
CA (1) CA3067021A1 (cg-RX-API-DMAC7.html)
WO (1) WO2018231865A2 (cg-RX-API-DMAC7.html)

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US8721620B2 (en) 2009-12-24 2014-05-13 Rani Therapeutics, Llc Swallowable drug delivery device and methods of drug delivery
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9402806B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809269B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10689460B2 (en) 2014-05-15 2020-06-23 Incube Labs, Llc PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
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US12569203B2 (en) * 2021-01-22 2026-03-10 Cilag Gmbh International Bariatric surgery post-surgical monitoring
US12670442B2 (en) * 2023-01-12 2026-06-30 Auden Techno Corp. Artificial intelligence capsule positioning system
CN119719690B (zh) * 2025-02-27 2025-06-20 北京亿家老小科技有限公司 一种多维度监控的饱腹感与占胃胶囊效果评估优化方法

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US5187154A (en) * 1990-12-13 1993-02-16 Board Of Regents, The University Of Texas System Diagnosis and treatment of humans with diabetes or at risk to develop diabetes
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US20060155174A1 (en) * 2002-12-16 2006-07-13 Arkady Glukhovsky Device, system and method for selective activation of in vivo sensors
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CA2514392A1 (en) 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
US7918786B2 (en) * 2003-11-11 2011-04-05 Olympus Corporation Capsule type medical device system, and capsule type medical device
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Also Published As

Publication number Publication date
JP2020523123A (ja) 2020-08-06
EP3638111A2 (en) 2020-04-22
WO2018231865A3 (en) 2020-02-06
JP7183194B2 (ja) 2022-12-05
JP2023010877A (ja) 2023-01-20
US20220008013A1 (en) 2022-01-13
AU2018282907B2 (en) 2023-12-07
WO2018231865A2 (en) 2018-12-20
US20180353133A1 (en) 2018-12-13
US11103187B2 (en) 2021-08-31
JP2024116415A (ja) 2024-08-27
EP3638111A4 (en) 2021-04-07
CN110996754A (zh) 2020-04-10
AU2018282907A1 (en) 2020-01-30
CA3067021A1 (en) 2018-12-20
CN115844361A (zh) 2023-03-28

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