CN110974152A - Automatic focusing fundus camera - Google Patents

Automatic focusing fundus camera Download PDF

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Publication number
CN110974152A
CN110974152A CN201911397588.8A CN201911397588A CN110974152A CN 110974152 A CN110974152 A CN 110974152A CN 201911397588 A CN201911397588 A CN 201911397588A CN 110974152 A CN110974152 A CN 110974152A
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light beam
fundus
lens assembly
diopter
imaging element
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CN201911397588.8A
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CN110974152B (en
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陈志�
陈大伟
龚明利
钟灿武
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Shenzhen Silicon Based Intelligent Technology Co ltd
Shenzhen Sibionics Intelligent Technology Co Ltd
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Shenzhen Silicon Based Intelligent Technology Co ltd
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Priority to CN202110876744.XA priority Critical patent/CN113558566B/en
Priority to CN202110876755.8A priority patent/CN113558568B/en
Priority to CN201911397588.8A priority patent/CN110974152B/en
Priority to CN202110876752.4A priority patent/CN113558567B/en
Publication of CN110974152A publication Critical patent/CN110974152A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/15—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
    • A61B3/152—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for aligning

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

The present disclosure relates to an auto-focusing fundus camera, which includes: a light source for emitting a first light beam and a second light beam towards a fundus of an eye, the first light beam being an eye-insensitive light beam; a lens assembly; an imaging element for receiving the first and second light beams through the lens assembly; a recording module for recording a first focus position when the first light beam is focused on the imaging element; the processing module is used for obtaining the diopter of the eyeball based on the wavelength of the first light beam, the diopter of the lens component and the first focusing position, and obtaining the second focusing position of the second light beam after the second light beam penetrates through the lens component based on the wavelength of the second light beam, the diopter of the eyeball and the diopter of the lens component; and a drive mechanism that adjusts a relative position between the lens assembly and the imaging element based on the second focus position. According to the automatic focusing method and device, automatic focusing can be accurately carried out on the fundus when the fundus image is collected, and light stimulation to eyes can be effectively reduced in the focusing process.

Description

Automatic focusing fundus camera
Technical Field
The present disclosure relates to an auto-focusing fundus camera.
Background
With the development of ophthalmic medicine, doctors and the like can diagnose whether or not a subject has a fundus disease by observing the fundus, for example, the retina, optic disc, blood vessel distribution, and the like. Currently, in clinical practice, a doctor or the like generally uses a fundus camera to acquire a fundus image of a human eye to observe the fundus.
The fundus camera may transmit a light beam to the fundus via the pupil and receive the reflected light beam to image the fundus. In the existing fundus camera, a single visible light is generally used for directly acquiring a fundus image, and the visible light is beneficial to illumination, so that the fundus camera can be used for acquiring an image of a dim fundus. For example, since the eye is sensitive to visible light, when collecting an image of the fundus of the eye and focusing the fundus of the eye using visible light, the pupil tends to contract in a short time when the eye is subjected to light stimulation, and too short a focusing time may make it difficult to accurately focus the fundus of the eye.
Disclosure of Invention
The present disclosure has been made in view of the above circumstances, and an object thereof is to provide a fundus camera capable of accurately performing autofocus on the fundus at the time of acquiring a fundus image and effectively reducing optical irritation to the eye during focusing.
To this end, the present disclosure provides a fundus camera characterized by comprising: a light source for sequentially emitting a first light beam and a second light beam toward a fundus of an eye, the first light beam being a light beam to which the eye is insensitive, and the second light beam having a wavelength less than that of the first light beam; a lens assembly that transmits the first light beam and the second light beam reflected by the fundus; an imaging element for receiving the first and second light beams transmitted through the lens assembly; the recording module is used for recording a first focusing position when the first light beam is reflected by the fundus and penetrates through the lens assembly to be focused on the imaging element; a processing module for obtaining a diopter of an eyeball based on the wavelength of the first light beam, the diopter of the lens assembly and the first focal position, and obtaining a second focal position at which the second light beam is reflected by the fundus and transmitted through the lens assembly based on the wavelength of the second light beam, the diopter of the eyeball and the diopter of the lens assembly; and a drive mechanism that adjusts a relative position between the lens assembly and the imaging element based on the second focus position.
In the fundus camera according to the present disclosure, the diopter of the eyeball is obtained by emitting the first light beam insensitive to the eye to the fundus, based on the wavelength of the first light beam, the diopter of the lens assembly, and the first focusing position where the first light beam is reflected by the fundus and transmitted through the lens assembly, the second focusing position where the second light beam is reflected by the fundus and transmitted through the lens assembly is obtained based on the wavelength of the second light beam, the diopter of the eyeball, and the diopter of the lens assembly, and the relative position between the lens assembly and the imaging element is automatically adjusted based on the second focusing position using the driving mechanism, whereby the fundus can be accurately automatically focused when acquiring the fundus image, and optical irritation to the eye can be effectively reduced in the focusing process.
In addition, in the fundus camera according to the present disclosure, optionally, the processing module further includes a lookup table, where the lookup table stores a mapping relationship between a wavelength of the simulated light beam, a diopter of the simulated eyeball, a diopter of the lens assembly, and a focusing position where the simulated light beam passes through the simulated eyeball and the lens assembly, which are established through a simulation experiment. In this case, the mapping relationship between the wavelength of the simulated light beam, the diopter of the simulated eyeball, the diopter of the lens assembly and the focusing position of the simulated light beam after passing through the simulated eyeball and the lens assembly is established through a simulation experiment, and a lookup table comprising a plurality of sets of mapping relationships can be accurately established.
In addition, in the fundus camera according to the present disclosure, optionally, the processing module obtains a diopter scale of the eyeball based on the wavelength of the first light beam, the diopter scale of the lens assembly, the first focusing position, and the lookup table, and the processing module obtains a second focusing position at which the second light beam is reflected by the fundus and transmitted through the lens assembly based on the wavelength of the second light beam, the diopter scale of the eyeball, the diopter scale of the lens assembly, and the lookup table. In this case, by comparing the known data with the look-up table, the diopter of the eyeball and the second in-focus position of the second light beam after being reflected by the fundus and transmitted through the lens assembly can be accurately obtained.
Further, in the fundus camera according to the present disclosure, optionally, the artificial light beam includes infrared light and visible light. In this case, by establishing a look-up table including infrared light and visible light, the in-focus position when infrared light or visible light is transmitted through the lens assembly can be conveniently obtained by the look-up table.
In addition, in the fundus camera according to the present disclosure, optionally, the diopter of the artificial eyeball includes-200D to + 200D. In this case, by covering the diopters of the real eyeball, a more complete lookup table can be established.
In addition, in the fundus camera according to the present disclosure, optionally, the first light beam is infrared light, and the second light beam is visible light. Therefore, the light stimulation to eyes can be effectively reduced in the focusing process.
In the fundus camera according to the present disclosure, the driving mechanism may drive the lens unit to move relative to the imaging unit, and when the second focus position is located at the imaging unit, the light source may emit the second light beam toward the fundus, and the second light beam may be reflected by the fundus and transmitted through the lens unit to form a fundus image on the imaging unit. In this case, by causing the second light beam to be reflected by the fundus and to be focused on the imaging element after passing through the lens assembly, a clear fundus image can be formed on the imaging element.
Further, in the fundus camera according to the present disclosure, optionally, a duration of emission of the second light beam to the fundus by the light source is not more than 100 ms. In this case, by controlling the duration of the second light beam within the time of pupil contraction, the energy consumption of the light source by the second light beam can be effectively reduced.
In addition, in the fundus camera according to the present disclosure, optionally, the optical axes of the lens assemblies are kept on the same straight line when the fundus camera performs image capturing. Therefore, the image of the fundus can be more clearly acquired.
Further, in the fundus camera according to the present disclosure, optionally, the fundus camera holds the fundus and the imaging element relatively still at the time of image acquisition. In this case, focusing of the fundus by adjusting the lens assembly can be facilitated by keeping the fundus and the imaging element relatively stationary.
According to the method and the device, automatic focusing can be accurately performed on the fundus when the fundus image is collected, and light stimulation to human eyes can be effectively reduced in the focusing process.
Drawings
The disclosure will now be explained in further detail by way of example only with reference to the accompanying drawings, in which:
fig. 1 is a schematic diagram illustrating a fundus camera according to an example of the present disclosure.
Fig. 2A is a schematic diagram illustrating a first focus position in accordance with an example of the present disclosure.
Fig. 2B is a schematic diagram illustrating a second focus position in accordance with an example of the present disclosure.
Fig. 3 is a schematic diagram illustrating a lookup table according to an example of the present disclosure.
Fig. 4 is a schematic flow chart showing acquisition of a fundus image by a fundus camera according to an example of the present disclosure.
Detailed Description
Hereinafter, preferred embodiments of the present disclosure will be described in detail with reference to the accompanying drawings. In the following description, the same components are denoted by the same reference numerals, and redundant description thereof is omitted. The drawings are schematic and the ratio of the dimensions of the components and the shapes of the components may be different from the actual ones.
It is noted that the terms "comprises," "comprising," and "having," and any variations thereof, in this disclosure, for example, a process, method, system, article, or apparatus that comprises or has a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include or have other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
In addition, the headings and the like referred to in the following description of the present disclosure are not intended to limit the content or scope of the present disclosure, but merely serve as a reminder for reading. Such a subtitle should neither be understood as a content for segmenting an article, nor should the content under the subtitle be limited to only the scope of the subtitle.
The present embodiment relates to an auto-focusing fundus camera. In the present embodiment, the fundus camera that automatically focuses may be simply referred to as a fundus camera. In this embodiment, the fundus camera may be used to capture a fundus image of a human eye, and the fundus camera may automatically focus the fundus when capturing the fundus image. Hereinafter, the fundus camera according to the present embodiment will be described in detail with reference to the drawings.
Fig. 1 is a schematic diagram showing a fundus camera 1 according to an example of the present disclosure. FIG. 2A is a diagram illustrating a first focus position P according to an example of the present disclosure1Schematic representation of (a). FIG. 2B is a diagram illustrating a second focus position P according to an example of the present disclosure2Schematic representation of (a).
In the present embodiment, the fundus camera 1 may include a light source 11, a lens assembly 12, an imaging element 13, a recording module 14, a processing module 15, and a driving mechanism 16 (see fig. 1).
The light source 11 may sequentially emit light beams of different wavelengths to the eye 2, and the light beams may be incident through the pupil 21 and may pass through the eyeball 22 to reach the fundus 23. Then, the light beam may be transmitted through the eyeball 22 and emitted through the pupil 21 after being reflected by the fundus 23, and the light beam may be transmitted through the lens assembly 12 and received by the imaging element 13 after being emitted through the pupil 21, thereby forming a fundus image on the imaging element 13 that may be used to display pathological information of the fundus 23.
In addition, the recording module 14 can be used to record the focusing position of the light beam after passing through the transmission assembly 12. The processing module 15 may obtain another unknown data based on any three known data of the wavelength of the light beam, the diopter of the eyeball 22, the diopter of the lens assembly 12, and the in-focus position of the light beam after being reflected off the fundus 23 and transmitted through the lens assembly 12. The driving mechanism 16 can automatically adjust the relative position between the lens assembly 12 and the imaging element 13 based on the in-focus position of the light beam after being reflected by the fundus 23 and transmitted through the lens assembly 13, so that the light beam is focused on the imaging element 13 after being reflected by the fundus 23 and transmitted through the lens assembly 13, thereby forming a clear fundus image on the imaging element 13.
Specifically, the image acquisition of the fundus 23 using the fundus camera 1 according to the present embodiment may include a focusing process on the fundus 23 and an acquisition process on a fundus image.
During focusing, the light source 11 may emit a first light beam L to the fundus 23 to which the eye 2 is insensitive1And adjusting the relative position between the lens assembly 12 and the imaging element 13 so that the first light beam L1Reflected by the fundus 23 and transmitted through the lens unit 12 to be focused on the imaging element 13. And the recording module 14 may record the first light beam L1A first focus position P when the fundus 23 is reflected and transmitted through the lens unit 12 and focused on the imaging element 131(see FIG. 2A). That is, when the first focus position P is reached1The first light beam L when positioned on the imaging element 131Reflected by the fundus 23 and transmitted through the lens assembly 12 may be focused on the imaging element 13. The processing module 15 may then be based on the first light beam L1The refractive power of the lens assembly 12 and the first focus position P1The diopter of the eyeball 22 is obtained, and the processing module 15 can be based on the second light beam L2The diopter of the eyeball 22 and the diopter of the lens assembly 12 to obtain the second light beam L2A second in-focus position P reflected by the fundus 23 and transmitted through the lens assembly 122(see FIG. 2B). The drive mechanism 16 may be based on the second focus position P2Automatically adjusting the relative position between the lens assembly 12 and the imaging element 13 to bring the second in-focus position P2Located in the imaging element 13.
During the acquisition process, when the second focus position P is reached2When positioned on the imaging element 13, the light source 11 may emit a second light beam L usable for illumination toward the fundus 232Thereby to pairThe fundus 23 is illuminated. In this case, the second light beam L2Reflected by the fundus 23 and transmitted through the lens assembly 12 may be focused on the imaging element 13, and a fundus image of the fundus 23 may be formed on the imaging element 13.
In the present embodiment, the in-focus position generally means: the beam is reflected by the fundus 23 and passes through the lens assembly 12 to a focused position. That is, the first focus position P1Refers to the first light beam L1A position where the light is reflected by the fundus 23 and focused after passing through the lens assembly 12, and a second in-focus position P2Refers to the second light beam L2Reflected by the fundus 23 and transmitted through the lens assembly 12 to be focused. Additionally, it should be noted that as the lens assembly 12 is moved, the in-focus position may move accordingly with the lens assembly 12.
In the fundus camera 1 according to the present embodiment, the first light beam L insensitive to the eye 2 is emitted to the fundus 231And based on the first light beam L1Of the lens assembly 12 and the first light beam L1A first focus position P after being reflected by the fundus 23 and transmitted through the lens unit 121Obtaining the diopter of eyeball 22 and based on second light beam P2The diopter of the eyeball 22 and the diopter of the lens assembly 12 to obtain the second light beam L2A second in-focus position P reflected by the fundus 23 and transmitted through the lens assembly 122And using the drive mechanism 16 based on the second focus position P2The relative position between the lens unit 12 and the imaging unit 13 is automatically adjusted, whereby the fundus 23 can be accurately focused at the time of acquiring a fundus image, and optical irritation to the eye 2 can be effectively reduced during focusing.
In the present embodiment, the fundus camera 1 may emit the first light beam L to the fundus 23 in sequence using the light source 111And a second light beam L2(see fig. 2A and 2B).
In some examples, the fundus camera 1 may emit the first light beam L to the fundus 23 using the light source 111To focus the fundus 23. And when focusing is completed, the fundus camera 1 may emit the second light beam L to the fundus 23 using the light source 112To the eye bottomImage acquisition is performed 23.
In some examples, the first light beam L emitted by the light source 11 toward the fundus 231May be infrared light. In some examples, the first light beam L emitted by the light source 11 toward the fundus 231The wavelength of (b) may be 760nm, 800nm, 850nm, 900nm, 950nm or 1000 nm. In this case, by focusing the fundus 23 using infrared light to which the eye 2 is not sensitive, it is possible to effectively reduce the optical irritation to the eye 2 in the process of focusing the fundus 23.
In some examples, the second light beam L emitted by the light source 11 toward the fundus 232May be visible light. In some examples, the second light beam L emitted by the light source 11 toward the fundus 232The wavelength of (b) may be 380nm, 400nm, 450nm, 500nm, 550nm, 600nm, 650nm, 700nm, 750nm or 780 nm. In this case, the fundus 23 is illuminated by visible light with a good illumination effect to perform image acquisition on the fundus 23, whereby image acquisition on the fundus 23 can be facilitated.
In some examples, the light source 11 emits the second light beam L to the fundus 23 at the time of image acquisition of the fundus 232May be no more than 100ms in duration. In some examples, the light source 11 emits a second light beam L to the fundus 232The duration of (c) may be 10ms, 15ms, 20ms, 25ms, 30ms, 35ms, 40ms, 45ms, 50ms, 55ms, 60ms, 65ms, 70ms, 75ms, 80ms, 85ms, 90ms, 95ms or 100 ms. In this case, when the second light beam L2When the eye 2 is stimulated, the pupil 21 contracts in a short time and the second light beam L is applied2Is controlled within the normal contraction time of the pupil 21, the second light beam L can be effectively reduced2Power consumption of the light source 11.
In some examples, the light source 11 may be positioned in a position such that when the optical axis of the lens assembly 12 is in a horizontal direction, the light source 11 may be positioned directly above the lens assembly 12. In some examples, the light source 11 may be positioned in a position such that when the optical axis of the lens assembly 12 is in a horizontal direction, the light source 11 may be located on a side of the lens assembly 12 away from the imaging element 13. Thereby, stray light between the lens assembly 12 and the imaging element 13 can be effectively reduced.
In some examples, the fundus camera 1 may keep the light source 11 and the fundus 23 relatively stationary at the time of image acquisition, that is, during the focusing process and the acquisition process of the fundus camera 1.
In the present embodiment, the first light beam L1And a second light beam L2After reflection from the fundus 23, may be transmitted through the lens assembly 12 (see fig. 2A and 2B).
In the present embodiment, the first light beam L1Can be focused at a first focus position P after being reflected by the fundus 23 and transmitted through the lens assembly 121Second light beam L2Can be focused at a second focus position P after being reflected by the fundus 23 and transmitted through the lens assembly 122(see fig. 2A and 2B). In addition, the first focus position P1And a second focus position P2May move accordingly with the movement of the lens assembly 12.
In some examples, the lens assembly 12 may be comprised of several lenses. In some examples, the lens assembly 12 may include a convex lens, a concave lens, a planar lens, or a cylindrical lens. In this case, the diopter of the lens assembly 12 can be easily adjusted by adjusting the relative positions between the respective lenses. In some examples, the in-focus position of the light beam after passing through the lens assembly 12 may be adjusted by adjusting the relative position between the various lenses. In some examples, the side of the lens assembly 12 near the eye 2 may have a condenser lens for condensing the light beam. Thereby, the lens assembly 12 can be facilitated to collect the light beam reflected by the fundus 23.
In some examples, the optical axis of the lens assembly 12 may be kept on the same straight line when the fundus camera 1 performs image acquisition, that is, during the focusing process and the acquisition process of the fundus camera 1. This enables the fundus 23 to be more clearly imaged.
In the present embodiment, the first light beam L1And a second light beam L2After being reflected by the fundus 23 and transmitted through the lens assembly 12, can be received by the imaging element 13 (see fig. 2A and 2B).
In the present embodiment, when the first focus is reachedPosition P1The first light beam L when positioned on the imaging element 131After being reflected by the fundus 23 and transmitted through the lens assembly 12, it can be focused on the imaging element 13. When the second focus position P2The second light beam L when positioned on the imaging element 132After being reflected by the fundus 23 and transmitted through the lens assembly 12, it can be focused on the imaging element 13.
In the present embodiment, when the second in-focus position P is set2When located in the imaging element 13, that is, when the second light beam L2Upon being reflected by the fundus 23 and passing through the lens assembly 13 to be focused on the imaging element 13, a fundus image of the fundus 23 can be formed on the imaging element 13.
In some examples, when the fundus camera 1 performs image acquisition, that is, during the focusing process and the acquisition process of the fundus camera 1, the fundus 23 and the imaging element 13 may be kept relatively stationary. In this case, by keeping the fundus 23 and the imaging element 13 relatively stationary, focusing by adjusting the lens assembly 12 can be facilitated.
In some examples, when the light source 11 emits the first light beam L to the fundus 231When the relative position between the lens assembly 12 and the imaging element 13 can be adjusted in real time, the first light beam L1A first focus position P when reflected by the fundus 23 and focused on the imaging element 13 through the lens unit 121I.e. at the imaging element 13.
In some examples, when the light source 11 emits the second light beam L to the fundus 232In this case, the relative position between the lens assembly 12 and the imaging element 13 can be adjusted, for example, the second focus position P can be adjusted by moving the lens assembly 122To the imaging element 13 to make the second light beam L2Reflected by the fundus 23 and transmitted through the lens assembly 12 to be focused on the imaging element 13, thereby forming a fundus image of the fundus 23 on the imaging element 13.
In some examples, the imaging element 13 may be a CMOS photosensitive element. In other examples, the imaging element 13 may be a CCD photosensitive element. However, the example of the present embodiment is not limited to this, and the image forming element 13 may be another element that can be used for photosensitive image formation.
In bookIn one embodiment, the first light beam L is emitted1The recording module 14 can be used for recording the relative position between the lens assembly 12 and the imaging element 13, namely the first light beam L, when the light is focused on the imaging element 13 after being reflected by the fundus 23 and transmitted through the lens assembly 121A first focus position P after being reflected by the fundus 23 and transmitted through the lens unit 121。
In some examples, the recording module 14 may also record the first light beam L1And the second light beam L2Of (c) is measured. In some examples, the recording module 14 may also record the diopter of the lens assembly 12. In some examples, the recording module 14 may record an initial relative position of the lens assembly 12 and the imaging element 13.
In some examples, the recording module 14 may have a memory to enable ease of recording data. In some examples, the recording module 14 may be in signal connection with the processing module 15, thereby enabling to facilitate recording of data, for example the first light beam L1And a first focus position P1To the processing module 15.
In the present embodiment, the processing module 15 can read the data recorded by the recording module 14, such as the first light beam L1The refractive power of the lens assembly 12 and the first focus position P1. Also, the processing module 15 may be based on the first light beam L1The refractive power of the lens assembly 12 and the first focus position P1Diopters of the eyeball 22 are obtained. The processing module 15 may also be based on the second light beam L2The diopter of the eyeball 22 and the diopter of the lens assembly 12 to obtain the second light beam L2A second in-focus position P reflected by the fundus 23 and transmitted through the lens assembly 122。
In some examples, the processing module 15 may include a look-up table, which may store a mapping relationship between the wavelength of the simulated light beam, the diopter of the simulated eyeball, the diopter of the lens assembly 12 and the focusing position of the simulated light beam after passing through the simulated eyeball and the lens assembly 12 (see fig. 3) established through simulation experiments. In this case, the mapping relationship between the wavelength of the simulated light beam, the diopter of the simulated eyeball, the diopter of the lens assembly 12 and the focusing position of the simulated light beam after passing through the simulated eyeball and the lens assembly 12 is established through a simulation experiment, and a lookup table including a plurality of sets of mapping relationships can be accurately established.
In some examples, the wavelengths of the simulated light beams in the lookup table may include the first light beam L1Wavelength λ of1And a second light beam L2Wavelength λ of2(see FIG. 3). In some examples, the simulated light beams in the lookup table may include infrared light and visible light. In some examples, the wavelengths of the simulated light beams in the lookup table may include 300nm to 1000 nm. In some examples, the wavelengths of the simulated light beams in the lookup table may include 380nm, 400nm, 450nm, 500nm, 550nm, 600nm, 650nm, 700nm, 750nm, 760nm, 780nm, 800nm, 850nm, 900nm, 950nm, or 1000 nm.
In some examples, the diopters of the simulated eyeballs in the lookup table may include diopter D of the eyeballs 22E(see FIG. 3). In some examples, the diopters of the simulated eye may include-200D to + 200D. In some examples, the diopter of the simulated eye can include-200D, -190D, -180D, -170D, -160D, -150D, -140D, -130D, -120D, -110D, -100D, -90D, -80D, -70D, -60D, -50D, -40D, -30D, -20D, -10D, 20D, 30D, 40D, 50D, 60D, 70D, 80D, 90D, 100D, 110D, 120D, 130D, 140D, 150D, 160D, 170D, 180D, 190D, or 200D
In some examples, the look-up table may include the diopter D of the lens assembly 12L(see FIG. 3). In some examples, the look-up table may also include the diopters of other lenses, thereby facilitating application of the look-up table to other cameras.
In some examples, the lookup table may include the first light beam L1Wavelength λ of1Diopter D of eyeball 22ERefractive power D of the lens assembly 12LAnd a first focus position P1The mapping relationship between them. In some examples, the look-up table may include the second light beam L2Wavelength λ of2Diopter D of eyeball 22ERefractive power D of the lens assembly 12LAnd a second focus position P2The mapping relationship between them (see fig. 3).
In some examples, the required unknown data may be obtained from known data and a look-up table. For example, the processing module 15 may be based on the first light beam L1Wavelength λ of1Refractive power D of the lens assembly 12LFirst focus position P1And row 1 in the look-up table to obtain diopter D of eyeball 22E(see FIG. 3). And the processing module 15 may also be based on the second light beam L2Wavelength λ of2Diopter D of eyeball 22ERefractive power D of the lens assembly 12LAnd the second light beam L is obtained from the 2 nd line of the lookup table2A second in-focus position P reflected by the fundus 23 and transmitted through the lens assembly 122(see FIG. 3).
In the present embodiment, the relative position between the lens assembly 12 and the imaging element 13 can be adjusted by using the driving mechanism 16.
In some examples, the drive mechanism 16 may be positioned where a line connecting the drive mechanism 16 and the lens assembly 12 may be perpendicular to an optical axis of the lens assembly 12. In some examples, the drive mechanism 16 may move in a line parallel to the optical axis of the lens assembly 12. In some examples, the drive mechanism 16 may drive the lens assembly 12 to move along an optical axis of the lens assembly 12.
In some examples, the drive mechanism 16 may drive the lens assembly 12 to move relative to the imaging element 13, thereby adjusting the relative position between the lens assembly 12 and the imaging element 13. In some examples, the drive mechanism 16 may be based on the first focus position P1And a second focus position P2The relative position between the lens assembly 12 and the imaging element 13 is automatically adjusted.
Specifically, in some examples, when the light source 11 emits the first light beam L1Thereafter, the drive mechanism 16 may drive the lens assembly 12 to bring the first focus position P1Located in the imaging element 13.
In some examples, when the first focus position P1Is moved to the imaging element 13 and the processing module 15 obtains a second focus position P2Thereafter, the processing module 15 may couple the second pairFocal position P2To the drive mechanism 16. The drive mechanism 16 may be based on the second focus position P2Driving the lens assembly 12 to adjust the relative position between the lens assembly 12 and the imaging element 13 when in the second focus position P2Being moved to the imaging element 13, the drive mechanism 16 may stop driving the lens assembly 12. In this case, the fundus camera 1 completes the focusing process on the fundus 23.
In some examples, when the second focus position P2When moved to the imaging element 13 by the driving mechanism 16, that is, when the focusing process is completed, the light source 11 may emit the second light beam L to the fundus 232Thereby performing an acquisition process of the fundus image.
In this case, the first focus position P is determined by using the drive mechanism 161And a second focus position P2Automatically adjusting the relative position between the lens assembly 12 and the imaging element 13 enables accurate autofocus of the fundus 23 at the time of image acquisition of the fundus 23.
Fig. 4 is a flowchart illustrating acquisition of a fundus image by the fundus camera 1 according to an example of the present disclosure. The acquisition of the fundus image by the fundus camera 1 will be described in detail below with reference to fig. 4.
First, the fundus camera 1 is brought into focus to infinity to perform initial calibration (step S100).
Next, the calibrated fundus camera 1 is aligned with the eye 2 to be harvested, and the light source 11 is used to emit light of wavelength λ to the fundus 231First light beam L1I.e., infrared light (step S200).
Then, the driving mechanism 16 drives the lens assembly 12 to move relative to the imaging element 13 to adjust the relative position between the lens assembly 12 and the imaging element 13. When the first light beam L1When the image is focused on the imaging element 13 after being reflected by the fundus 23 and transmitted through the lens assembly 12, the recording module 14 records the position of the imaging element 13 relative to the lens assembly 12 at that time as a first focus position P1(step S300).
Subsequently, the processing module 15 is based on the first light beam L1Wavelength λ of1Refractive power D of the lens assembly 12LIn the field ofThe first in-focus position P obtained in step S3001And line 1 in the look-up table, the diopter D of the eyeball 22 is obtainedE(step S400).
Subsequently, the processing module 15 is based on the second light beam L2I.e. wavelength lambda of visible light2And the diopter D of the eyeball 22 obtained in step S400ERefractive power D of the lens assembly 12LAnd row 2 in the look-up table, obtaining a second light beam L2A second in-focus position P reflected by the fundus 23 and transmitted through the lens assembly 122(step S500).
Then, the driving mechanism 16 drives the lens assembly 12 to move relative to the imaging element 13 to move the second in-focus position P obtained in step S5002To the imaging element 13 (step S600).
Finally, when the second focus position P is reached2The light source 11 emits the second light beam L having a duration less than 100ms toward the fundus 23 while being positioned on the imaging element 132Second light beam L2After being reflected by the fundus 23 and transmitted through the lens unit 12, the image is focused on the imaging element 13 and a fundus image of the fundus 23 is formed on the imaging element 13 (step S700)
It should be noted that, in step S500, the processing module 15 may be based on the second light beam L2Wavelength λ of2And obtaining the second focus position P by the lookup table2But at this time the light source 11 does not emit the second light beam L towards the fundus 232Preferably, the light source 11 is in the second focus position P in step S7002Emits the second light beam L again to the fundus 23 while being positioned in the imaging element 132. In addition, in the process of performing steps S200 to S700, the optical axes of the lens assembly 12 are kept on the same straight line, and the relative position of the imaging element 13 and the eye 2 is kept unchanged.
According to the present disclosure, the fundus 23 can be accurately focused at the time of acquiring a fundus image, and optical stimulation to the eye 2 can be effectively reduced during focusing.
While the present disclosure has been described in detail in connection with the drawings and examples, it should be understood that the above description is not intended to limit the disclosure in any way. Those skilled in the art can make modifications and variations to the present disclosure as needed without departing from the true spirit and scope of the disclosure, which fall within the scope of the disclosure.

Claims (10)

1. An automatic focusing fundus camera is characterized in that,
the method comprises the following steps:
a light source for sequentially emitting a first light beam and a second light beam toward a fundus of an eye, the first light beam being a light beam to which the eye is insensitive, and the second light beam having a wavelength less than that of the first light beam;
a lens assembly that transmits the first light beam and the second light beam reflected by the fundus;
an imaging element for receiving the first and second light beams transmitted through the lens assembly;
the recording module is used for recording a first focusing position when the first light beam is reflected by the fundus and penetrates through the lens assembly to be focused on the imaging element;
a processing module for obtaining a diopter of an eyeball of the eye based on the wavelength of the first light beam, the diopter of the lens assembly, and the first in-focus position, and obtaining a second in-focus position after the second light beam is reflected by the fundus and transmitted through the lens assembly based on the wavelength of the second light beam, the diopter of the eyeball, and the diopter of the lens assembly; and
a drive mechanism that adjusts a relative position between the lens assembly and the imaging element based on the second focus position.
2. The fundus camera according to claim 1,
the processing module further comprises a lookup table, and the lookup table stores the mapping relationship between the wavelength of the simulated light beam, the diopter of the simulated eyeball, the diopter of the lens assembly and the focusing position of the simulated light beam after penetrating through the simulated eyeball and the lens assembly, which are established through a simulation experiment.
3. The fundus camera according to claim 2,
the processing module obtains a diopter of the eyeball based on the wavelength of the first light beam, the diopter of the lens assembly, the first focus position, and the lookup table,
the processing module obtains a second focusing position of the second light beam after the second light beam is reflected by the fundus and penetrates through the lens assembly based on the wavelength of the second light beam, the diopter of the eyeball, the diopter of the lens assembly and the lookup table.
4. The fundus camera according to claim 2,
the simulated light beam comprises infrared light and visible light.
5. The fundus camera according to claim 2,
the diopter of the simulated eyeball comprises-200D to + 200D.
6. The fundus camera according to claim 1,
the first light beam is infrared light, and the second light beam is visible light.
7. The fundus camera according to claim 1,
the driving mechanism drives the lens assembly to move relative to the imaging element,
when the second focus position is located on the imaging element, the light source emits the second light beam to the fundus, and the second light beam forms a fundus image on the imaging element after being reflected by the fundus and transmitting through the lens assembly.
8. The fundus camera according to claim 7,
the duration of the emission of the second light beam by the light source to the fundus is not more than 100 ms.
9. The fundus camera according to claim 1,
when the fundus camera collects images, the optical axes of the lens assemblies are kept on the same straight line.
10. The fundus camera according to claim 1,
when the fundus camera collects images, the fundus and the imaging element are kept still relatively.
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