CN110947094A - Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array - Google Patents
Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array Download PDFInfo
- Publication number
- CN110947094A CN110947094A CN201911365096.0A CN201911365096A CN110947094A CN 110947094 A CN110947094 A CN 110947094A CN 201911365096 A CN201911365096 A CN 201911365096A CN 110947094 A CN110947094 A CN 110947094A
- Authority
- CN
- China
- Prior art keywords
- electrode
- module
- contacts
- plate
- fixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0558—Anchoring or fixation means therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention discloses an implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array, which comprises a plate electrode module, an electrode lead module, an electrode interface module and an electrode fixing module, wherein the plate electrode module is electrically connected with the electrode lead module, the electrode interface module is electrically connected with the electrode lead module, the electrode fixing module is fixed on the electrode lead module, and the electrode array is further fixed on a part to be tested or a part to be stimulated. The electrode array can be used for collecting spinal cord electric signals and can also be used for carrying out electric stimulation on the spinal cord. And the electrode array can be adapted to a human body or other vertebrates by scaling up or down the size of the electrode plates. The electrode array has the advantages of being tightly attached to the dura mater of the spinal cord, having a plurality of contacts, being easy to adopt spinal cord electrical signals or apply electrical stimulation signals to the spinal cord, being easy to fix and the like.
Description
Technical Field
The invention relates to an electrode structure, in particular to an implanted and applied nerve electric signal acquisition and functional electric stimulation electrode array.
Background
The collection of spinal cord electrical signals and the functional electrical stimulation of the spinal cord are of great significance in both neuroscience research and rehabilitation medicine applications. The application of the electrical stimulation signal to the spinal cord is of great significance to the inhibition of the conduction of pain sensory signals and the restoration of motor function of paralyzed limbs caused by spinal cord injury. Both the collection of electrical spinal cord signals and the application of electrical stimulation signals to the spinal cord require appropriate electrodes as interface devices.
At present, few implantable flexible electrodes suitable for spinal cords are available, most common nerve electrodes are not suitable for spinal cords, such as sieve electrodes, sword electrodes, Utah electrodes named by Utah university in the United states, Michigan electrodes named by Michigan university in the United states and the like can cause injuries to spinal cords, and spiral electrodes, skin electrodes and the like are difficult to wrap spinal cords.
Disclosure of Invention
The purpose of the invention is as follows: aiming at the defects of the prior art, the invention provides an implanted and applied nerve electric signal acquisition and functional electric stimulation electrode array used for spinal epidural.
The technical scheme is as follows: in order to realize the purpose, the invention adopts the following technical scheme:
an implanted and applied nerve electrical signal acquisition and functional electrical stimulation electrode array comprises an electrode plate module, an electrode lead module, an electrode interface module and an electrode fixing module, wherein the electrode plate module is electrically connected with the electrode lead module, the electrode interface module is electrically connected with the electrode lead module, the electrode fixing module is fixed on the electrode lead module, and the electrode array is further fixed on a part to be tested or stimulated.
Optionally, the electrode plate module includes an arc-shaped electrode plate and a plurality of electrode contacts, the electrode contacts are fixed on the concave surface of the arc-shaped electrode plate, and the electrode contacts collect a nerve electrical signal of the to-be-measured portion or apply an electrical stimulation signal to the to-be-stimulated portion (i.e., the target portion).
Optionally, 18 electrode contacts on the arc-shaped electrode plate are arranged in 6 rows and 3 columns, 3 electrode contacts in each row form a three-electrode structure, and the noise can be effectively reduced by acquiring electrical signals in a double-differential mode.
Optionally, the electrode lead module includes two electrode leads, and the two electrode leads are connected to the arc-shaped electrode plate of the electrode plate module, and are configured to transmit the electrical signal of the nerve at the position to be measured, acquired by the electrode contact of the electrode plate module, to the electrode interface module, or transmit the electrical signal of the external device received by the electrode interface module to the electrode contact of the electrode plate module.
Optionally, the electrode interface module includes a plurality of interface contacts, the number of the interface contacts is the same as that of the electrode contacts on the electrode plate module, the interface contacts correspond to the electrode contacts on the arc-shaped electrode plate one by one, and the interface contacts of the electrode interface module are used for transmitting the electric signals of the part to be tested acquired by the electrode contacts of the electrode plate module to an external device or transmitting the stimulation electric signals transmitted by the external device to the electrode contacts.
Optionally, the electrode fixing module comprises two fixing anchors, and the fixing anchors penetrate through the electrode lead module and are used for fixing the electrode array to the part to be measured or stimulated.
Optionally, the fixing anchor includes a first fixing ring, a second fixing ring and a connecting portion, one end of the connecting portion is fixedly connected to the lower end of the first fixing ring, the other end of the connecting portion is fixedly connected to the upper end of the second fixing ring, the first fixing ring is provided with a fixing plate, the fixing plate is an elliptical plate, and two tips of the elliptical plate extend outward and are provided with fixing holes; the structure of the second fixing ring is the same as that of the second fixing ring.
Has the advantages that: compared with the prior art, the invention has the following advantages:
(1) the radian of the electrode plate array is consistent with that of the surface of the spinal cord, so that the electrode contacts are attached to the dura mater of the spinal cord more tightly.
(2) The 3 electrode contacts in each row of the electrode array can form a three-electrode structure, signals can be collected in a double-difference mode, and noise is further reduced.
(3) The electrode array can be used as a spinal cord electric signal acquisition electrode and can also be used for applying an electric stimulation signal to the spinal cord.
(4) The length and width of the electrode plate of the electrode array can be linearly adjusted according to the size of the spinal cord of an experimental object, and the electrode has a plurality of electrode contacts, so that the electrode is suitable for all vertebrates.
(5) The special fixing anchor for the electrode array can ensure that the electrode can be well fixed after being implanted, the position of the electrode relative to the spinal cord is not easy to change, and the stability is good.
(6) The implantation site of the electrode array is outside the dura mater, and the spinal cord cannot be directly damaged.
Drawings
FIG. 1 is a schematic diagram of an electrode array configuration according to the present invention;
FIG. 2 is a front view of an electrode plate;
FIG. 3 is a top view of the tie-down anchor;
fig. 4 is a front view of the tie-down anchor.
Detailed Description
The technical solution of the present invention is described in detail below with reference to the accompanying drawings and specific embodiments.
As shown in fig. 1, an implanted and applied type nerve electrical signal collecting and functional electrical stimulation electrode array includes an electrode plate module 100, an electrode lead module 110, an electrode interface module 120 and an electrode fixing module 130, wherein the electrode plate module is electrically connected with the electrode lead module, the electrode interface module is electrically connected with the electrode lead module, the electrode fixing module is fixed on the electrode lead module, and further the electrode array is fixed on a to-be-measured portion or a to-be-stimulated portion.
The electrode plate module 100 includes an arc-shaped electrode plate 101 and a plurality of electrode contacts 102, the electrode contacts are fixed on the concave surface of the arc-shaped electrode plate, and electrical signals of spinal nerves are collected or electrical stimulation signals are applied to the spinal cord through the electrode contacts.
The electrode lead module 110 includes two electrode leads 111, and the two electrode leads are connected to the electrode plate and used for transmitting the electrical spinal cord signal collected by the electrode contact to the electrode interface module, or transmitting the electrical stimulation signal of the external device received by the electrode interface module to the electrode contact of the electrode plate module.
The electrode interface module 120 includes 18 interface contacts 121 corresponding to the electrode contacts on the arc-shaped electrode plate one by one, and is used for transmitting the spinal cord electrical signals collected by the electrode contacts to an external device or transmitting the electrical signals transmitted by the external device to the electrode contacts.
The electrode fixation module 130 contains two fixation anchors 131, one on each bundle of electrode leads, for fixation of the electrodes after implantation of the electrodes outside the spinal epidural. The anchor may be moved along the electrode lead, and after the anchor is moved to a suitable position, a non-absorbable suture may be wrapped around the middle of the anchor so that the anchor is fixed to the electrode lead. The four circular holes on either side of the anchor can then be sutured to the supraspinal ligament or deep fascia adjacent the spinal cord with non-absorbable sutures to effect fixation of the electrode array.
As shown in fig. 2, the arc-shaped electrode plate is designed according to the radian of the surface of the spinal cord, so that the electrode contact of the concave surface of the arc-shaped electrode plate can be tightly attached to the spinal cord. In the embodiment, the number of the electrode contacts on the arc-shaped electrode plate is 18, the 18 electrode contacts are arranged in 6 rows and 3 columns, the 3 electrode contacts in each row can form a three-electrode structure, and the noise can be effectively reduced by acquiring electric signals in a double-differential mode. Each electrode lead tail end is provided with 9 exposed interface contacts 121, and 18 interface contacts at the two electrode lead tail ends correspond to 18 electrode contacts on the arc-shaped electrode plate one by one to form an electrode interface module.
As shown in fig. 3 and 4, each of the fixing anchors includes a first fixing ring 1310, a second fixing ring 1311, and a connecting portion 1312, one end of which is fixedly connected to a lower end of the first fixing ring and the other end of which is fixedly connected to an upper end of the second fixing ring. The first fixing ring is provided with a fixing plate, the fixing plate is oval, two tips of the oval extend outwards, and a fixing hole 1313 is formed in the fixing plate; the structure of the second fixing ring is the same as that of the second fixing ring.
Each electrode lead has a fixation anchor 131 movable with the lead wire, the fixation anchor being movable along the electrode lead, and after being moved to a suitable position, a non-absorbable suture may be wrapped around a connecting portion 1312 at the center of the fixation anchor to fix the fixation anchor to the electrode lead. The four fixation holes 1313 on either side of the anchor can then be sutured to the supraspinal ligament or deep fascia near the spinal cord with non-absorbable sutures to effect fixation of the electrode array.
The invention relates to an implanted application type nerve electric signal acquisition and functional electric stimulation electrode array. The electrode array has 18 electrode contacts, and the electrode contacts are uniformly distributed on the arc-shaped electrode plate according to the arrangement mode of 6 rows and 3 columns. The radian of the arc-shaped electrode plate is the same as that of the surface of the spinal cord, so that the arc-shaped electrode plate can be tightly attached to the dura mater of the spinal cord. The arc electrode plate is connected with two bundles of electrode leads, and the tail end of each bundle of electrode leads is respectively provided with 9 exposed interface contacts. 18 electrode contacts on the arc-shaped electrode plates of the 18 interface contacts at the tail ends of the two electrode leads are in one-to-one correspondence. Fixation of the electrode array may be achieved by threading the electrode lead through a specially made fixation anchor and suturing the fixation anchor to the supraspinous ligament or deep fascia. The electrode array can be used for collecting spinal cord electric signals and performing functional electric stimulation on the spinal cord. And the electrode array can be suitable for different human bodies or other vertebrates by scaling up or down the size of the arc-shaped electrode plate. The electrode array has the advantages of being tightly attached to the dura mater of the spinal cord, having a plurality of contacts, being easy to adopt spinal cord electrical signals or apply electrical stimulation signals to the spinal cord, being easy to fix and the like.
Claims (7)
1. An implanted and applied nerve electric signal acquisition and functional electric stimulation electrode array is characterized by comprising an electrode plate module (100), an electrode lead module (110), an electrode interface module (120) and an electrode fixing module (130), wherein the electrode plate module is electrically connected with the electrode lead module, the electrode interface module is electrically connected with the electrode lead module, the electrode fixing module is fixed on the electrode lead module, and the electrode array is further fixed on a part to be detected or stimulated.
2. The electrode plate module comprises an arc-shaped electrode plate (101) and a plurality of electrode contacts (102), wherein the electrode contacts are fixed on the concave surface of the arc-shaped electrode plate, and the electrode contacts collect nerve electrical signals of a part to be measured or apply electrical stimulation signals to a target part.
3. The electrode array for implantable applied neuroelectrical signal collection and functional electrical stimulation according to claim 2, wherein the electrode contacts on the arc-shaped electrode plate are 18, the 18 electrode contacts are arranged in 6 rows and 3 columns, and the 3 electrode contacts on each row form a three-electrode structure.
4. The electrode array for collecting nerve electrical signals and stimulating function through implant application according to claim 1, wherein the electrode lead module comprises two electrode leads (111), and the two electrode leads are connected with the arc-shaped electrode plate of the electrode plate module and used for conducting the nerve electrical signals of the part to be measured collected by the electrode contact of the electrode plate module to the electrode interface module or transmitting the electrical signals of an external device received by the electrode interface module to the electrode contact of the electrode plate module.
5. The electrode array for collecting nerve electrical signals and stimulating function by implantation and application according to claim 1, wherein the electrode interface module comprises a plurality of interface contacts (121), the number of the interface contacts is the same as that of the electrode contacts on the electrode plate module, the interface contacts correspond to the electrode contacts on the arc-shaped electrode plate one by one, and the interface contacts of the electrode interface module are used for transmitting the electrical signals of the part to be measured collected by the electrode contacts of the electrode plate module to an external device or transmitting the electrical signals transmitted by the external device to the electrode contacts.
6. The electrode array for implantable neural electrical signal collection and functional electrical stimulation according to claim 1, wherein the electrode fixing module comprises two fixing anchors (131) passing through the electrode lead module for fixing the electrode array to the site to be measured.
7. The implant-applied neuroelectrical signal collection and functional electrical stimulation electrode array of claim 6, wherein the anchor comprises a first fixing ring (1310), a second fixing ring (1311), and a connecting portion (1312), one end of the connecting portion is fixedly connected to the lower end of the first fixing ring, the other end of the connecting portion is fixedly connected to the upper end of the second fixing ring, the first fixing ring is provided with a fixing plate, the fixing plate is an elliptical plate, the two tips of the elliptical plate extend outwards and are provided with fixing holes (1313); the structure of the second fixing ring is the same as that of the first fixing ring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911365096.0A CN110947094A (en) | 2019-12-26 | 2019-12-26 | Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911365096.0A CN110947094A (en) | 2019-12-26 | 2019-12-26 | Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110947094A true CN110947094A (en) | 2020-04-03 |
Family
ID=69984339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911365096.0A Pending CN110947094A (en) | 2019-12-26 | 2019-12-26 | Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110947094A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111812173A (en) * | 2020-09-07 | 2020-10-23 | 博睿康科技（常州）股份有限公司 | Intelligent electrode |
| CN113456433A (en) * | 2021-08-13 | 2021-10-01 | 北京大学人民医院 | Electric signal collector and human-computer interaction interface type exoskeleton rehabilitation system |
| WO2022126612A1 (en) * | 2020-12-18 | 2022-06-23 | 深圳先进技术研究院 | Fixing device |
| CN116271516A (en) * | 2023-03-29 | 2023-06-23 | 中国人民解放军军事科学院军事医学研究院 | Spinal cord epidural implantation multi-mode patch electrode |
| WO2023240695A1 (en) * | 2022-06-17 | 2023-12-21 | 中国科学院脑科学与智能技术卓越创新中心 | Flexible electrode for spinal cord and method for manufacturing same |
-
2019
- 2019-12-26 CN CN201911365096.0A patent/CN110947094A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111812173A (en) * | 2020-09-07 | 2020-10-23 | 博睿康科技（常州）股份有限公司 | Intelligent electrode |
| WO2022126612A1 (en) * | 2020-12-18 | 2022-06-23 | 深圳先进技术研究院 | Fixing device |
| CN113456433A (en) * | 2021-08-13 | 2021-10-01 | 北京大学人民医院 | Electric signal collector and human-computer interaction interface type exoskeleton rehabilitation system |
| CN113456433B (en) * | 2021-08-13 | 2023-06-23 | 北京大学人民医院 | Electric signal collector and human-computer interaction interface type exoskeleton rehabilitation system |
| WO2023240695A1 (en) * | 2022-06-17 | 2023-12-21 | 中国科学院脑科学与智能技术卓越创新中心 | Flexible electrode for spinal cord and method for manufacturing same |
| CN116271516A (en) * | 2023-03-29 | 2023-06-23 | 中国人民解放军军事科学院军事医学研究院 | Spinal cord epidural implantation multi-mode patch electrode |
| CN116271516B (en) * | 2023-03-29 | 2023-11-14 | 中国人民解放军军事科学院军事医学研究院 | Spinal cord epidural implantation multi-mode patch electrode |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110947094A (en) | Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array | |
| US9889293B2 (en) | Implantable medical lead for stimulation of multiple nerves | |
| US9504839B2 (en) | Tension clamp side loading lead anchor and methods and systems using the lead anchor | |
| US10406353B2 (en) | Electrical stimulation leads with anchoring unit and electrode arrangement and methods of making and using | |
| EP1370322B1 (en) | Lead with adjustable angular and spatial relationships between electrodes | |
| CA2398962A1 (en) | Medical implant device for electrostimulation using discrete micro-electrodes | |
| AU2014265848B2 (en) | Electrical stimulation leads and systems with anchoring units and methods of making and using | |
| Lo et al. | 22.2 A 176-channel 0.5 cm3 0.7 g wireless implant for motor function recovery after spinal cord injury | |
| Navarro et al. | Selective fascicular stimulation of the rat sciatic nerve with multipolar polyimide cuff electrodes | |
| US11944814B2 (en) | Wireless implant for motor function recovery after spinal cord injury | |
| CN110975136A (en) | Implanted nerve electrical signal acquisition and functional electrical stimulation electrode | |
| Bugbee et al. | An implant for chronic selective stimulation of nerves | |
| CN212038602U (en) | Implanted and applied nerve electric signal acquisition and functional electrical stimulation electrode array | |
| US20050278009A1 (en) | Electrode for electrostimulators | |
| Sharma et al. | Bidirectional telemetry controller for neuroprosthetic devices | |
| US6163727A (en) | Hook shaped spinal cord electrode assembly | |
| EP4257176A1 (en) | Device and method for electrically stimulating at least one nerve | |
| CN212038601U (en) | Implanted nerve electrical signal acquisition and functional electrical stimulation electrode | |
| CN104922794A (en) | Position evaluation apparatus of testing stimulation electrode | |
| CN204864539U (en) | Test stimulating electrode's position evaluation device | |
| Koh et al. | An implantable electrical interface for in vivo studies of the neuromuscular system | |
| Yu et al. | A cable-tie-type parylene cuff electrode for peripheral nerve interfaces | |
| US20220362560A1 (en) | Systems and methods for measuring temperature on or near an implantable medical device | |
| Tao et al. | Effects of different configurations of multi-contact cuff electrode on recruitment characteristics of nerve stimulation | |
| Thota et al. | A Multi-lead Multi-electrode System for Neural-interface Enabled Advanced Prostheses |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |