CN110942826B - System and method for quantifying cerebral vein information in human intracranial angiography - Google Patents

System and method for quantifying cerebral vein information in human intracranial angiography Download PDF

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CN110942826B
CN110942826B CN201911323679.7A CN201911323679A CN110942826B CN 110942826 B CN110942826 B CN 110942826B CN 201911323679 A CN201911323679 A CN 201911323679A CN 110942826 B CN110942826 B CN 110942826B
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dsa
cct
quiet
imaging
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CN110942826A (en
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黄光�
唐煜
刘加春
石祥恩
李延峰
李晓光
徐蔚海
李永杰
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FU XING HOSPITAL CAPITAL MEDICAL UNIVERSITY
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FU XING HOSPITAL CAPITAL MEDICAL UNIVERSITY
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images

Abstract

The invention discloses a system and a method for quantizing cerebral vein information in human intracranial angiography, wherein the system comprises the following steps: digital subtractionAn angiography machine for cerebrovascular imaging of a patient; an information acquisition unit: the DSA imaging system is used for acquiring personal information of a patient, personal historical cerebrovascular imaging quantitative data information and obtaining DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine; a data processing unit: used for quantifying the DSA cerebrovascular imaging information and calculating the venous period time T Quiet And total arteriovenous circulation time T CCT And performing preliminary examination on the calculation result, and calculating the cerebral venous circulation index T when the preliminary examination is qualified Quiet /T CCT (ii) a An output unit: for outputting the processing result of the data processing unit. The cerebral venous circulation index can be used for better assisting in diagnosing venous reflux disorder diseases such as thrombosis of intracranial veins and venous sinuses and the like, and eliminating the influence of factors such as hypertension, diabetes, intracranial pressure increase and the like on cerebral arteriovenous circulation time, so that the diagnosis result is more accurate.

Description

System and method for quantifying cerebral vein information in human intracranial angiography
Technical Field
The invention relates to the technical field of medicine, in particular to a system and a method for quantizing cerebral vein information in human intracranial angiography.
Background
Intracranial venous and venous sinus thrombosis is rare in clinic, but the clinical forms are various, the clinical manifestations are different, misdiagnosis or missed diagnosis is often performed, the disability rate and the fatality rate are high, and meanwhile, as the cause of the thrombosis is not clearly known, the existing clinical treatment means and the evaluation method lack unified standards. Based on the current situation, a multicenter expert consensus group for diagnosis and treatment of venous and venous sinus thrombosis in 2013 formulated skullChinese expert consensus on diagnosis and treatment of thrombosis of internal vein and venous sinus [1] (hereinafter referred to as "consensus"), the DSA is referred to as the standard for diagnosing intracranial venous and venous sinus thrombus: (1) the main manifestation is that the venous sinus is completely blocked by thrombus and the 'empty sinus phenomenon' occurs; (2) other signs may be poor visualization of cortical or deep veins, prolonged arteriovenous circulation (mainly venous duration > 10 seconds), occurrence of venous reflux, etc.
However, there are many factors affecting the arteriovenous circulation time of the brain, and except the pathological state of the cerebral blood vessel itself, hypertension, diabetes, high intracranial pressure and the like all affect the arteriovenous circulation time of the brain to different degrees, and the venous period time diagnosis method does not exclude the influence of the factors. At present, no research is available at home and abroad for obtaining cerebral arteriovenous circulation time by a DSA method and diagnosing intracranial vein and venous sinus thrombosis by the cerebral arteriovenous circulation time.
Reference documents:
[1] the Chinese experts of diagnosis and treatment of thrombus of venous sinus and venous sinus commonly know [ J ]. Chinese internal medicine journal, 2013,52 (12): 1088-1091.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a cerebral vein information quantification system and method in human intracranial angiography, which can eliminate the influence of factors such as hypertension, diabetes, intracranial hypertension and the like on cerebral arteriovenous circulation time and can assist in more accurately diagnosing venous return abnormality caused by thrombosis of intracranial veins and venous sinuses.
In order to achieve the purpose, the invention adopts the following technical scheme:
a system for quantifying cerebral vein information in human intracranial angiography comprises:
a digital subtraction angiography machine for cerebrovascular imaging of a patient;
an information acquisition unit: the DSA imaging system is used for acquiring personal information of a patient, personal historical cerebrovascular imaging quantitative data information and obtaining DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine;
a data processing unit:
the method is used for quantifying DSA cerebrovascular imaging information, and specifically comprises the steps of recording time information T1 of intracardiac artery cavernous sinus segment development, time information T2 of cortical vein development and time information T3 of sigmoid sinus disappearance according to the DSA cerebrovascular imaging information, and calculating venous period time T according to the following formula Quiet And total arteriovenous circulation time T CCT ：
T Quiet ＝T3-T2；
T CCT ＝T3-T1；
Quantitative data information for reference personal historical cerebrovascular imaging and combination of clinical state and calculated venous period time T Quiet And total arteriovenous circulation time T CCT Performing comparison and initial examination, and calculating the obtained T Quiet And T CCT If the quantitative data information of the relative personal historical cerebrovascular imaging is synchronously increased or reduced, the basic clinical state is met, and the initial examination is qualified, otherwise, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again; if the patient is treated, when T Quiet And T CCT When the DSA is reduced synchronously, the DSA meets the clinical state, the initial examination is qualified, otherwise, the DSA does not meet the clinical state in form, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again;
for at venous phase time T Quiet And total arteriovenous circulation time T CCT Calculating the cerebral venous circulation index T when the preliminary examination is qualified Quiet /T CCT ；
An output unit: for outputting the processing result of the data processing unit.
Further, the output unit is used for outputting the result data to a storage device and outputting the result data as an electronic document.
The invention also provides a method for utilizing the cerebral vein information quantification system in human intracranial angiography, which comprises the following specific processes:
using a digital subtraction angiography machine to image the cerebral vessels of the patient;
acquiring personal information and personal historical cerebrovascular imaging quantitative data information of a patient through an information acquisition unit, and acquiring DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine, wherein the information acquisition unit transmits the acquired and acquired information to a data processing unit;
the data processing unit quantifies the DSA cerebrovascular imaging information, records time information T1 of intracarotid artery cavernous sinus segment development, time information T2 of cortical vein development and time information T3 of sigmoid sinus disappearance according to the DSA cerebrovascular imaging information, and calculates venous period time T according to the following formula Quiet And total arteriovenous circulation time T CCT ：
T Quiet ＝T3-T2；
T CCT ＝T3-T1；
Then the data processing unit refers to the personal historical cerebrovascular imaging quantitative data information and combines the clinical state with the calculated venous period time T Quiet And total arteriovenous circulation time T CCT Performing comparison and initial examination, and calculating to obtain T Quiet And T CCT If the quantitative data information of the relative personal historical cerebrovascular imaging is synchronously increased or reduced, the basic clinical state is met, and the initial examination is qualified, otherwise, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again; if the patient is treated, when T Quiet And T CCT When the DSA is reduced synchronously, the DSA meets the clinical state, the initial examination is qualified, otherwise, the DSA does not meet the clinical state in form, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again;
after the initial examination is qualified, the data processing unit calculates the cerebral venous circulation index T Quiet /T CCT ；
The processing result of the data processing unit is output through the output unit.
Further, the output unit outputs the result data to a storage device and outputs as an electronic document.
The invention has the beneficial effects that:
the system and the method can obtain the cerebral venous circulation index (T) Quiet /T CCT ) The cerebral venous circulation index can be used for better assisting in diagnosing the intracranial veins and the venous sinusesThe venous return disturbance diseases such as thrombosis and the like, and the influence of factors such as hypertension, diabetes, intracranial hypertension and the like on the cerebral arteriovenous circulation time is eliminated, so that the diagnosis result is more accurate.
Drawings
FIG. 1 is a schematic diagram showing the composition of a system in example 1 of the present invention;
fig. 2 is a diagram showing normal value ranges of vein parameters in embodiment 2 of the present invention.
Detailed Description
The present invention will be further described with reference to the accompanying drawings, and it should be noted that the present embodiment is based on the technical solution, and the detailed implementation and the specific operation process are provided, but the protection scope of the present invention is not limited to the present embodiment.
Example 1
The present embodiment provides a system for quantifying cerebral vein information in human intracranial angiography, as shown in fig. 1, including:
a digital subtraction angiography machine for cerebrovascular imaging of a patient;
an information acquisition unit: the DSA imaging system is used for acquiring personal information of a patient, personal historical cerebrovascular imaging quantitative data information and obtaining DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine;
a data processing unit:
the method is used for quantifying DSA cerebrovascular imaging information, and specifically comprises the steps of recording time information T1 of intracardiac artery cavernous sinus segment development, time information T2 of cortical vein development and time information T3 of sigmoid sinus disappearance according to the DSA cerebrovascular imaging information, and calculating venous period time T according to the following formula Quiet And total arteriovenous circulation time T CCT ：
T Quiet ＝T3-T2；
T CCT ＝T3-T1；
Quantitative data information for reference personal historical cerebrovascular imaging and combination of clinical state and calculated venous period time T Quiet And total arteriovenous circulation time T CCT Performing comparison and initial examination, and calculating to obtain T Quiet And T CCT If the quantitative data information of the relative personal historical cerebrovascular imaging is synchronously increased or reduced, the basic clinical state is met, and the initial examination is qualified, otherwise, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again; if the patient is treated, when T Quiet And T CCT When the DSA is reduced synchronously, the DSA meets the clinical state, the initial examination is qualified, otherwise, the DSA does not meet the clinical state in form, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again;
for at venous phase time T Quiet And total arteriovenous circulation time T CCT Calculating the cerebral venous circulation index T when the brain venous circulation index is qualified in the initial examination Quiet /T CCT ；
An output unit: for outputting the processing result of the data processing unit.
Further, the output unit is used for outputting the result data to a storage device and outputting the result data as an electronic document.
Example 2
The embodiment provides a method for utilizing the system for quantifying cerebral vein information in human intracranial angiography described in embodiment 1, which specifically comprises the following steps:
using a digital subtraction angiography machine to perform cerebrovascular imaging on a patient;
acquiring personal information and personal historical cerebrovascular imaging quantitative data information of a patient through an information acquisition unit, and acquiring DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine, wherein the information acquisition unit transmits the acquired and acquired information to a data processing unit;
the data processing unit quantifies the DSA cerebrovascular imaging information, specifically records time information T1 of intracarotid artery cavernous sinus segment development, time information T2 of cortical vein development and time information T3 of sigmoid sinus disappearance according to the DSA cerebrovascular imaging information, and calculates venous period time T according to the following formula Quiet And total arteriovenous circulation time T CCT ：
T Quiet ＝T3-T2；
T CCT ＝T3-T1；
Then the data processing unit refers to the personal historical cerebrovascular imaging quantitative data information and combines the clinical state with the calculated venous period time T Quiet And total arteriovenous circulation time T CCT Performing comparison and initial examination, and calculating to obtain T Quiet And T CCT If the quantitative data information of the relative personal historical cerebrovascular imaging is synchronously increased or reduced, the basic clinical state is met, and the initial examination is qualified, otherwise, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again; if the patient is treated, when T Quiet And T CCT When the DSA is reduced synchronously, the DSA meets the clinical state, the initial examination is qualified, otherwise, the DSA does not meet the clinical state in form, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again;
after the initial examination is qualified, the data processing unit calculates the cerebral venous circulation index T Quiet /T CCT ；
The processing result of the data processing unit is output through the output unit.
Further, the output unit outputs the result data to a storage device and outputs as an electronic document.
In practical application, the obtained cerebral venous circulation index T Quiet /T CCT The analysis can be performed based on the normal value. The cerebral venous circulation index is less than or equal to 73.3 and belongs to venous reflux disorder, wherein the index is analyzed from the normal cases of the cerebral venous reflux of 116 cerebral veins in two hospitals. The normal value range of the vein parameters is shown in fig. 2.
Various corresponding changes and modifications can be made by those skilled in the art based on the above technical solutions and concepts, and all such changes and modifications should be included in the protection scope of the present invention.

Claims (4)

1. A system for quantifying cerebral vein information in human intracranial angiography, comprising:
a digital subtraction angiography machine for cerebrovascular imaging of a patient;
an information acquisition unit: the DSA imaging system is used for acquiring personal information of a patient, personal historical cerebrovascular imaging quantitative data information and obtaining DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine;
a data processing unit:
the method is used for quantifying DSA cerebrovascular imaging information, and specifically comprises the steps of recording time information T1 of intracardiac artery cavernous sinus segment development, time information T2 of cortical vein development and time information T3 of sigmoid sinus disappearance according to the DSA cerebrovascular imaging information, and calculating venous period time T according to the following formula Quiet And total arteriovenous circulation time T CCT ：
T Quiet ＝T3-T2；
T CCT ＝T3-T1；
Quantitative data information for imaging of reference individual historical cerebral blood vessels and combined with clinical state to calculated venous phase time T Quiet And total arteriovenous circulation time T CCT Performing comparison and initial examination, and calculating to obtain T Quiet And T CCT If the quantitative data information of the relative personal historical cerebrovascular imaging is synchronously increased or reduced, the quantitative data information is in accordance with the clinical state and qualified in initial examination, otherwise, the quantitative data information of the DSA cerebrovascular imaging needs to be quantized again if the quantitative data information of the relative personal historical cerebrovascular imaging is unqualified in initial examination; if the patient is treated, when T Quiet And T CCT When the DSA is reduced synchronously, the DSA meets the clinical state, the initial examination is qualified, otherwise, the DSA does not meet the clinical state in form, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again;
for at venous phase time T Quiet And total arteriovenous circulation time T CCT Calculating the cerebral venous circulation index T when the preliminary examination is qualified Quiet /T CCT ；
An output unit: for outputting the processing result of the data processing unit.
2. The system of claim 1, wherein the output unit is configured to output the result data to a storage device and as an electronic document.
3. The method for utilizing the system for quantifying the cerebral vein information in the human intracranial angiography of any one of claims 1-2 is characterized by comprising the following specific processes:
using a digital subtraction angiography machine to perform cerebrovascular imaging on a patient;
acquiring personal information and personal historical cerebrovascular imaging quantitative data information of a patient through an information acquisition unit, and acquiring DSA cerebrovascular imaging information of the patient from a digital subtraction angiography machine, wherein the information acquisition unit transmits the acquired and acquired information to a data processing unit;
the data processing unit quantifies the DSA cerebrovascular imaging information, records time information T1 of intracarotid artery cavernous sinus segment development, time information T2 of cortical vein development and time information T3 of sigmoid sinus disappearance according to the DSA cerebrovascular imaging information, and calculates venous period time T according to the following formula Quiet And total arteriovenous circulation time T CCT ：
T Quiet ＝T3-T2；
T CCT ＝T3-T1；
Then the data processing unit refers to the personal historical cerebrovascular imaging quantitative data information and combines the clinical state with the calculated venous period time T Quiet And total arteriovenous circulation time T CCT Performing comparison and initial examination, and calculating the obtained T Quiet And T CCT If the quantitative data information of the relative personal historical cerebrovascular imaging is synchronously increased or reduced, the quantitative data information is in accordance with the clinical state and qualified in initial examination, otherwise, the quantitative data information of the DSA cerebrovascular imaging needs to be quantized again if the quantitative data information of the relative personal historical cerebrovascular imaging is unqualified in initial examination; if the patient is treated, when T Quiet And T CCT When the DSA is reduced synchronously, the DSA meets the clinical state, the initial examination is qualified, otherwise, the DSA does not meet the clinical state in form, the initial examination is unqualified, and the DSA cerebrovascular imaging information needs to be quantized again;
after the initial examination is qualified, the data processing unit calculates the cerebral venous circulation index T Quiet /T CCT ；
The processing result of the data processing unit is output through the output unit.
4. The method according to claim 3, wherein the output unit outputs the result data to a storage device and as an electronic document.
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