CN1108833C - Infusion device capable of reducing medicine adsorption and its making process - Google Patents
Infusion device capable of reducing medicine adsorption and its making process Download PDFInfo
- Publication number
- CN1108833C CN1108833C CN97105975A CN97105975A CN1108833C CN 1108833 C CN1108833 C CN 1108833C CN 97105975 A CN97105975 A CN 97105975A CN 97105975 A CN97105975 A CN 97105975A CN 1108833 C CN1108833 C CN 1108833C
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- Prior art keywords
- infusion device
- medicine
- binding agent
- conduit
- pvc
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Abstract
The present invention provides a disposable infusion device capable of reducing medicine adsorption and a preparation method thereof. A duct and a liquid dropping kettle of the disposable infusion device are made of polyethylene. Connection among the duct, the liquid dropping kettle and a filter are in interference fit and adhesives are added for filling gaps. The present invention greatly reduces medicine adsorption in the disposable infusion device and has the advantages of stable medicine concentration and accurate dosage administration. Connection fastness and tightness between components accord with the national standard of a PVC infusion device and clinical requirements. The present invention is particularly suitable for the infusion of medicine which is easy to be absorbed by the PVC infusion device.
Description
The present invention relates to disposable transfusion device of a kind of reduced medicine absorption that comprises conduit, liquid dripping kettle, liquid medicine filter and flow regulator and preparation method thereof, be particularly useful for the transfusion higher the stability requirement of drug level.
Widely used disposable transfusion device on the hospital clinical at home and abroad at present, its material mostly is polrvinyl chloride (calling PVC in the following text), discovers recently, and the PVC transfusion device has in various degree absorption to many medicines, medicine is lost in tube for transfusion, influenced medication effect.
Adopt bonding way between each parts of PVC transfusion device, be to be bonding agent with the cyclohexanone, and it is used for polyethylene (calling PE in the following text) transfusion device, indexs such as the fastness of its connection do not reach requirement, thereby are not suitable for the preparation of PE transfusion device.
The disposable transfusion device that the reduced medicine of being made up of conduit, liquid dripping kettle, liquid medicine filter and flow regulator adsorbs, CN2058606U promptly is a kind of like this technology; EP39999A1 discloses a kind of disposable transfusion device simultaneously, replace the PVC material with polythene material, this technology has been represented and the immediate prior art of present patent application, but in this patent record adopt behind the polythene material by with the mode of binding agent with the technical scheme that connects between conduit and liquid dripping kettle, the filter.Adopt the bonding mode of binding agent, the composition of binding agent must make and connect the index request that reaches fastness.
The object of the present invention is to provide a kind of preparation method that reduces the disposable transfusion device of medicine absorption, fastness that connects between each parts of transfusion device and seal all meet the standard and the clinical requirement of national PVC transfusion device.
The preparation method that reduces the disposable transfusion device of medicine absorption of the present invention, comprise conduit, liquid dripping kettle, liquid medicine filter and flow regulator, one end and the liquid dripping kettle of conduit link, the other end and liquid medicine filter link, it is characterized in that: the material of conduit, liquid dripping kettle is a polyethylene, adopt the interference assembling between conduit and liquid dripping kettle, the filter and add the mode of filling out binding agent short covering crack and connect, the described binding agent of filling out that adds is made up of powder material of polyvinyl chloride and Ketohexamethylene, contains powder material of polyvinyl chloride 5g～15g in the 100ml binding agent.
Advantage of the present invention is to have significantly reduced the absorption of medicine in transfusion device, and drug level is stable, and it is accurate to advance dose; And connection fastness between each parts of transfusion device and seal all meet the standard and the clinical requirement of national PVC transfusion device.
Embodiment 1:
Be mixed with binding agent according to containing the 13g powder material of polyvinyl chloride in the 100ml binding agent, make the PE syringe, compare with the PVC transfusion device, the nimotop vial that certain pharmaceutical factory of instiling respectively produces compares as follows to its transfusion content:
Annotate: a_ represents that the content of sampling and measuring is represented with ug/ml from infusion bottle.
B_ represents from the content of syringe needle for transfusion device sampling and measuring.
Loss rate=(a-b) * 100/a.
Embodiment 2
Equally, compare with 0.9% sodium chloride injection of the chlorpromazine hydrochloride of concentration 9mg/l, the result is with PVC medicine average loss rate 41%, and PE does not lose.
Embodiment 3
Be made into binding agent according to containing the 6g powder material of polyvinyl chloride in the 100ml binding agent, the Buddhist nun who produces with certain factory is in flat fluid drip equally, and the result is with PVC medicine average loss rate 44%, and PE is 6.5%.
Embodiment 4
Be made into binding agent according to containing the 14g powder material of polyvinyl chloride in the 100ml binding agent, 0.9% sodium chloride injection with the chlorpromazine hydrochloride of concentration 9mg/l compares equally, and the result is with PVC medicine average loss rate 43%, and PE does not lose.
Claims (1)
1, a kind of preparation method that reduces the disposable transfusion device of medicine absorption, comprise conduit, liquid dripping kettle, liquid medicine filter and flow regulator, one end and the liquid dripping kettle of conduit link, the other end and liquid medicine filter link, it is characterized in that: the material of conduit, liquid dripping kettle is a polyethylene, adopt the interference assembling between conduit and liquid dripping kettle, the filter and add the mode of filling out binding agent short covering crack and connect, the described binding agent of filling out that adds is made up of powder material of polyvinyl chloride and cyclohexanone, contains powder material of polyvinyl chloride 5g～15g in the 100ml binding agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97105975A CN1108833C (en) | 1997-07-17 | 1997-07-17 | Infusion device capable of reducing medicine adsorption and its making process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97105975A CN1108833C (en) | 1997-07-17 | 1997-07-17 | Infusion device capable of reducing medicine adsorption and its making process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1205899A CN1205899A (en) | 1999-01-27 |
| CN1108833C true CN1108833C (en) | 2003-05-21 |
Family
ID=5168258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97105975A Expired - Lifetime CN1108833C (en) | 1997-07-17 | 1997-07-17 | Infusion device capable of reducing medicine adsorption and its making process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1108833C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110079245A (en) * | 2019-05-17 | 2019-08-02 | 深圳市凯思特医疗科技股份有限公司 | A kind of binder and its preparation method and application |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0039999A1 (en) * | 1980-05-09 | 1981-11-18 | Warner-Lambert Company | Nitroglycerin infusion set |
| US4561110A (en) * | 1982-01-07 | 1985-12-24 | Fresenius Ag | Bag for the storage of liquids |
| CN2208929Y (en) * | 1994-05-05 | 1995-10-04 | 杜高峰 | Disposable transfusion device |
| CN2243902Y (en) * | 1996-02-16 | 1997-01-01 | 崔海 | Disposable translucidus blood transfusion and transfusion device |
-
1997
- 1997-07-17 CN CN97105975A patent/CN1108833C/en not_active Expired - Lifetime
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0039999A1 (en) * | 1980-05-09 | 1981-11-18 | Warner-Lambert Company | Nitroglycerin infusion set |
| US4561110A (en) * | 1982-01-07 | 1985-12-24 | Fresenius Ag | Bag for the storage of liquids |
| CN2208929Y (en) * | 1994-05-05 | 1995-10-04 | 杜高峰 | Disposable transfusion device |
| CN2243902Y (en) * | 1996-02-16 | 1997-01-01 | 崔海 | Disposable translucidus blood transfusion and transfusion device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1205899A (en) | 1999-01-27 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20030521 |
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| CX01 | Expiry of patent term |