CN110840506A - Embolism system - Google Patents
Embolism system Download PDFInfo
- Publication number
- CN110840506A CN110840506A CN201911147257.9A CN201911147257A CN110840506A CN 110840506 A CN110840506 A CN 110840506A CN 201911147257 A CN201911147257 A CN 201911147257A CN 110840506 A CN110840506 A CN 110840506A
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- China
- Prior art keywords
- embolus
- embolization
- pushing rod
- locking component
- stent
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
- A61B17/12118—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm for positioning in conjunction with a stent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/1215—Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00862—Material properties elastic or resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
Abstract
The invention provides an embolus system, which comprises a catheter, an embolus and a pushing rod, wherein the pushing rod is movably connected with the embolus through an interlocking mechanism, the pushing rod can move along an inner cavity of the catheter to push the embolus to a preset position, and when the embolus is pushed to the preset position, the embolus is released by rotating the pushing rod. The embolus device of the embolus system can be processed into different lengths and diameters, and is suitable for blood vessels with different diameters; the embolus device has high resilience and memory, can automatically expand in the blood vessel to block blood flow, and reduces the risk of displacement; the embolism is complete, multiple embolism is not needed, and the operation time and the operation cost are reduced; simple structure, convenient operation and recovery.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to an embolism system for embolism treatment.
Background
Embolism treatment is an important technology in minimally invasive interventional therapy and also one of three major technologies of interventional radiology, and has been applied to treatment of tumors in multiple parts of the whole body, such as Transcatheter Arterial Chemoembolization (TACE) and Uterine Arterial Embolization (UAE). The embolization device is a necessary medical device in embolization treatment, and is used for embolizing tumor blood vessels and promoting ischemia and necrosis of tumors.
The most ideal embolism instrument can fill the vascular lumens with different diameters, does not shift, has complete embolism, controllable degradation time and good controllability. Common embolism products in the market comprise spring rings, gelatin sponge, PVA (polyvinyl alcohol), sodium alginate microspheres, NBCA (N-bromosuccinimide), degradable starch microspheres, alcohol, super-liquefied iodine oil, autologous blood clots and the like. Although the variety of embolization materials is numerous, these products all have their own advantages and disadvantages, and none are the most desirable products for general use. For example, the spring ring can be used for embolizing a large blood vessel, but the gap is large, so that embolization is difficult to complete at one time, a plurality of spring rings need to be placed, and even NBCA or PVA is needed to fill the gap, so that the operation time and cost are greatly increased. Gelatin sponge, PVA, sodium alginate microspheres, degradable starch microspheres, alcohol super-liquefied iodized oil and autologous blood clots are not easy to control and are easy to shift in vivo, so that incomplete embolism or dislocation embolism is caused. The NBCA glue is fast in curing, poor in controllability and high in operating technical requirements for operators.
Therefore, a new therapeutic device is needed to overcome the above disadvantages, so as to further advance the device, reduce the operation time and the pain of the patient, and promote the clinical application of the embolization device.
Disclosure of Invention
In order to solve the technical problem, the invention provides an embolism system with a novel structure.
The embolization system comprises a catheter, an embolization device and a pushing rod, wherein the pushing rod is movably connected with the embolization device through an interlocking mechanism, the pushing rod can move along an inner cavity of the catheter to push the embolization device to a preset position, and when the embolization device is pushed to the preset position, the embolization device is released by rotating the pushing rod.
In one embodiment, the embolus device comprises a bracket and filler wrapping the bracket, the bracket is streamline, at least one end of the bracket is provided with a first locking component, and the filler can form thrombus with blood after the embolus device is sent into a human body.
In one embodiment, one end of the pushing rod is provided with a second locking component matched with the first locking component, the first locking component and the second locking component are locked together through mutual buckling, and after the plug is pushed to the preset position, the first locking component and the second locking component are unlocked through rotating the pushing rod.
In one embodiment, the scaffold and the filler are molded by insert injection foaming.
In one embodiment, one end of the conduit is provided with a developer ring, and the end of the conduit at the end provided with the developer ring is rounded.
In one embodiment, the first locking member is a hook and the second locking member is a hook or a ring.
In one embodiment, the stent is formed of a material having superelasticity and memory, and the filler is composed of a polyester foam material or a degradable polymer material having high resilience and microporous properties.
In one embodiment, both ends of the bracket are provided with first locking components.
In one embodiment, the stent is a diamond-shaped structure or other similar streamlined structure machined from nitinol material.
In one embodiment, the embolization device is sized to be 10% to 20% larger than the diameter of the blood vessel.
In one embodiment, the first locking member and the bracket are joined together by welding; the second locking assembly and the push rod are connected together through welding.
Compared with the prior art, the embolus device of the embolus system can be processed into different lengths and diameters, and is suitable for blood vessels with different diameters; the embolus device has high resilience and memory, can automatically expand in the blood vessel to block blood flow, and reduces the risk of displacement; the embolism is complete, multiple embolism is not needed, and the operation time and the operation cost are reduced; simple structure, convenient operation and recovery.
The technical features described above can be combined in various technically feasible ways to produce new embodiments, as long as the object of the invention is achieved.
Drawings
The invention will be described in more detail hereinafter on the basis of non-limiting examples only and with reference to the accompanying drawings. Wherein:
FIG. 1 illustrates one embodiment of an embolization system according to the present invention;
FIG. 2 shows a schematic structural view of the stent of the embolization device of FIG. 1;
FIG. 3 shows a top view of the bracket of FIG. 2;
FIG. 4 shows a schematic view of the structure of the packing of FIG. 2;
FIG. 5 shows the embolization device of FIG. 1 in a post-release configuration within a blood vessel;
FIG. 6 shows an enlarged view of the body-insertable end of the embolization system of FIG. 1;
FIG. 7 shows an enlarged view of the extracorporeal end of the embolization system of FIG. 1.
In the drawings, like components are denoted by like reference numerals. The figures are not drawn to scale.
Wherein the reference numerals, which are given,
10. an embolization system; 1. a conduit; 11. a developing ring; 2. an emboliser; 21. a support; 22. a filler; 211. a first locking assembly; 3. a push rod; 31. a second locking assembly.
Detailed Description
The invention will be described in further detail below with reference to the drawings and specific examples. It should be noted that, as long as there is no conflict, the embodiments and the features of the embodiments of the present invention may be combined with each other, and the technical solutions formed are within the scope of the present invention.
Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs. The terms "first," "second," and the like, as used herein do not denote any order, quantity, or importance, but rather are used to distinguish one element from another. The word "comprising" or "comprises", and the like, means that the element or item listed before the word covers the element or item listed after the word and its equivalents, but does not exclude other elements or items. The terms "connected" or "coupled" and the like are not restricted to physical or mechanical connections, but may include electrical connections, whether direct or indirect.
Parts which are not described in the invention can be realized by adopting or referring to the prior art.
As shown in fig. 1, the present invention provides an embolic system, comprising a catheter 1, an embolic device 2 and a pushing rod 3, wherein the pushing rod 3 is movably connected with the embolic device 2 through an interlocking mechanism, the pushing rod 3 can move along the inner cavity of the catheter 1 to push the embolic device 2 to a predetermined position, and the embolic device 2 can be released by rotating the pushing rod 3.
As shown in fig. 2-5, the embolus device 2 comprises a bracket 21 and a filler 22 covering the bracket 21, wherein the bracket 21 is streamline, and the filler 22 can form thrombus with blood after the embolus device 2 is sent into a human body.
As shown in fig. 6 and 7, at least one end of the bracket 21 is provided with a first locking component 211, one end of the pushing rod 3 is provided with a second locking component 31 matched with the first locking component 211, the first locking component 211 and the second locking component 31 are locked together by mutual buckling, and after the plug device 2 is pushed to a preset position, the first locking component 211 and the second locking component 31 are unlocked by rotating the pushing rod 3.
Preferably, the stent 21 is a streamlined diamond structure machined from nitinol material, which facilitates loading, release and retrieval of the embolic device 2. When the embolus 2 is released in vivo, one of the first locking components 211 of the bracket 21 and the second locking component 31 of the pushing rod 3 are locked together under the constraint of the catheter 1, and the other end of the pushing rod 3 is held by a doctor so that the embolus 2 can be released and retracted in vivo. When the embolus 2 is pushed out of the catheter, the pushing rod 3 is rotated by the pushing rod 1 to be separated, and the release of the embolus 2 is completed. If the embolus 2 left in the body needs to be retrieved, the snare can be used to cover the first locking element 211 on the stent 2 and pull it into the sheath for retrieval.
More preferably, the first locking component 211 of the stent 21 is provided with two locking components, which are respectively arranged at two ends of the stent 21 to facilitate bidirectional recovery, and the snare and the sheath are commercially mature medical products, which will not be described herein.
In one embodiment, the stent 21 is formed from a material having superelasticity and memory, preferably a nickel titanium alloy. The filler 22 is made of polyester foam material, which has the characteristics of softness, high compression amount, high resilience and microporous property, and can form thrombus with blood to achieve the effect of blocking blood embolism. Due to the microporous structure, the medical filler can be immersed in ultra-liquefied iodized oil, alcohol or other therapeutic drugs to promote the formation of thrombus, achieve the purpose of treatment and prevent the filler 22 from bringing air into blood vessels. The filler 22 can also be a degradable polymer material with similar properties, the degradation time of which is controlled by the component ratio.
In one embodiment, the bracket 21 and the filler 22 are formed by insert injection foam molding, that is, the processed bracket 21 is placed in a mold of a foam molding machine, and then the mold is closed and injection foam molding is performed, and the filler 23 covers the bracket 21 to form a whole.
When the device is used, the outer diameter of the embolism device 2 is reduced in a pressing and holding mode and is inserted into the catheter 1, the first locking component 21 at one end of the embolism device 2 and the second locking component 31 of the pushing rod 3 are interlocked in the catheter 1, and a doctor releases and retracts the embolism device 2 by controlling the pushing rod 3 outside the body. When the embolus device 2 is pushed out from the catheter 1, the polyester foam also has high resilience due to the superelasticity and shape memory characteristics of the nickel-titanium alloy, so that the polyester foam can be automatically expanded and clamped in a blood vessel of a diseased part to block blood flow.
Preferably, the embolization device 2 can be made into different lengths and diameters, and can be made into various specifications to fill blood vessels with different thicknesses, and the embolization device 2 is usually made into a specification which is 10% -20% larger than the diameter of the blood vessel, so that the embolization device can be prevented from being propped in the blood vessel.
In one embodiment, one end of the catheter 1 is provided with a visualization ring 11 to facilitate viewing of the position of the catheter in the body, and the end of the catheter 1 at the end provided with the visualization ring 11 is rounded. Specifically, the developing ring 11 is disposed at one end of the catheter 1 inserted into the human body, and the end of the one end inserted into the human body is rounded, so that the pushing resistance of the catheter 1 in the human body can be reduced, and the risk of the blood vessel of the human body being punctured is also reduced.
Preferably, the catheter 1 is made of polypropylene or other polymer material with similar properties by extrusion.
In a specific embodiment, the first locking member 21 is a hook and the second locking member 31 is a hook or a ring. When the device is used, one hook of the support 2 and the hook or the ring of the push rod 3 are hooked together under the constraint of the catheter 1 to form an interlocking structure, a doctor can control the release and retraction of the embolic device 2 in a body by holding the other end of the push rod 3, and after the embolic device 2 is completely pushed out of the catheter 1, the push rod 3 is rotated to separate, so that the release of the embolic device 2 is completed.
Preferably, the first locking member 211 and the bracket 21 are connected together by welding; the second locking assembly 31 is connected with the push rod 3 by welding. Alternatively, the first locking component 211 and the bracket 21 may also be formed as an integral structure, and the second locking component 31 and the pushing rod 3 may be formed as an integral structure, and the specific forming manner is not limited in the present invention.
It will thus be appreciated by those skilled in the art that while the invention has been described with reference to a preferred embodiment, various changes may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention. In particular, the technical features mentioned in the embodiments can be combined in any way as long as there is no structural conflict. It is intended that the invention not be limited to the particular embodiments disclosed, but that the invention will include all embodiments falling within the scope of the appended claims.
Claims (10)
1. The embolism system (10) is characterized in that the embolism system (10) comprises a catheter (1), an embolus (2) and a pushing rod (3), wherein the embolus (2) is movably connected with the pushing rod (3) through an interlocking mechanism, the pushing rod (3) can move along an inner cavity of the catheter (1) so as to push the embolus (2) to a preset position, and after the embolus (2) is pushed to the preset position, the embolus (2) is released through rotating the pushing rod (3).
2. The embolization system of claim 1, wherein the embolization device (2) comprises a stent (21) and a filler (22) covering the stent (21), the stent (21) is streamlined, at least one end of the stent (21) is provided with a first locking component (211), and the filler (22) is capable of thrombogenic with blood after the embolization device (2) is delivered into a human body.
3. The embolization system according to claim 2, wherein one end of the pushing rod (3) is provided with a second locking component (31) which is matched with the first locking component (211), the first locking component (211) and the second locking component (31) are locked together by mutual buckling, and after the embolization device (2) is pushed to the preset position, the first locking component (211) and the second locking component (31) are unlocked by rotating the pushing rod (3).
4. The embolization system of claim 2, wherein the scaffold (21) and the filler (22) are molded by insert injection foaming.
5. The embolization system according to any one of claims 1-4, wherein one end of the catheter (1) is provided with a visualization ring (11) and the end of the catheter (1) at which the visualization ring (11) is provided is rounded.
6. The embolization system of claim 3, wherein the first locking component (211) is a hook and the second locking component (31) is a hook.
7. The embolization system of claim 2, wherein the stent (21) is formed of a material having superelasticity and memory, and the filler (22) is formed of a polyester foam material or a degradable polymeric material having high resilience and microporous properties.
8. The embolization system of claim 2 or 6, wherein both ends of the stent (21) are provided with a first locking member (211).
9. The embolization system of any one of claims 2-4 or 7, wherein the stent (21) is a diamond-shaped structure machined from a nickel titanium alloy material.
10. The embolization system of claim 3 or 4, wherein the first locking member (211) and the bracket (21) are connected together by welding; the second locking assembly (31) and the push rod (3) are connected together through welding.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201911147257.9A CN110840506A (en) | 2019-11-21 | 2019-11-21 | Embolism system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201911147257.9A CN110840506A (en) | 2019-11-21 | 2019-11-21 | Embolism system |
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CN110840506A true CN110840506A (en) | 2020-02-28 |
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CN201911147257.9A Pending CN110840506A (en) | 2019-11-21 | 2019-11-21 | Embolism system |
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Citations (11)
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JPH06508274A (en) * | 1991-06-07 | 1994-09-22 | ピー. マークス,マイケル | Catheter device with retractable wire and method thereof |
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CN1331956A (en) * | 2001-07-06 | 2002-01-23 | 周星 | Reusable temporary thrombus filter |
US20070203519A1 (en) * | 2006-02-28 | 2007-08-30 | Lorenzo Juan A | Embolic device delivery system |
CN201088640Y (en) * | 2007-10-22 | 2008-07-23 | 北京有色金属研究总院 | Recycle device of inferior caval vein colander |
CN101416890A (en) * | 2007-10-22 | 2009-04-29 | 北京有色金属研究总院 | Inferior vena cava filter recovery device |
CN102046094A (en) * | 2008-03-26 | 2011-05-04 | 马尔特·诺伊斯 | Device for closing defects in the vascular system |
CN205144794U (en) * | 2015-10-23 | 2016-04-13 | 李雷 | Recovery system of embolism protection device and embolism filter |
CN106068107A (en) * | 2014-01-10 | 2016-11-02 | 南洋理工大学 | Embolization device, apparatus for thromboembolism target vessel position and method thereof |
CN106214205A (en) * | 2016-07-26 | 2016-12-14 | 加奇生物科技(上海)有限公司苏州分公司 | Arteries induction system |
CN108992202A (en) * | 2018-08-14 | 2018-12-14 | 内蒙古工业大学 | A kind of not damaged retrievable vena cava filter |
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2019
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Publication number | Priority date | Publication date | Assignee | Title |
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JPH06508274A (en) * | 1991-06-07 | 1994-09-22 | ピー. マークス,マイケル | Catheter device with retractable wire and method thereof |
JPH06511174A (en) * | 1991-12-12 | 1994-12-15 | ターゲット セラピューティクス,インコーポレイテッド | Detachable pusher with interlocking ball and keyway connection - vaso-occlusive coil assembly |
CN1331956A (en) * | 2001-07-06 | 2002-01-23 | 周星 | Reusable temporary thrombus filter |
US20070203519A1 (en) * | 2006-02-28 | 2007-08-30 | Lorenzo Juan A | Embolic device delivery system |
CN201088640Y (en) * | 2007-10-22 | 2008-07-23 | 北京有色金属研究总院 | Recycle device of inferior caval vein colander |
CN101416890A (en) * | 2007-10-22 | 2009-04-29 | 北京有色金属研究总院 | Inferior vena cava filter recovery device |
CN102046094A (en) * | 2008-03-26 | 2011-05-04 | 马尔特·诺伊斯 | Device for closing defects in the vascular system |
CN106068107A (en) * | 2014-01-10 | 2016-11-02 | 南洋理工大学 | Embolization device, apparatus for thromboembolism target vessel position and method thereof |
CN205144794U (en) * | 2015-10-23 | 2016-04-13 | 李雷 | Recovery system of embolism protection device and embolism filter |
CN106214205A (en) * | 2016-07-26 | 2016-12-14 | 加奇生物科技(上海)有限公司苏州分公司 | Arteries induction system |
CN108992202A (en) * | 2018-08-14 | 2018-12-14 | 内蒙古工业大学 | A kind of not damaged retrievable vena cava filter |
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