CN110787677A - Reation kettle for bio-pharmaceuticals - Google Patents

Reation kettle for bio-pharmaceuticals Download PDF

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Publication number
CN110787677A
CN110787677A CN201911134835.5A CN201911134835A CN110787677A CN 110787677 A CN110787677 A CN 110787677A CN 201911134835 A CN201911134835 A CN 201911134835A CN 110787677 A CN110787677 A CN 110787677A
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CN
China
Prior art keywords
wall
motor
bio
kettle body
protective shell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911134835.5A
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Chinese (zh)
Inventor
姜正清
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hubei Zhengtong Pharmaceutical Co Ltd
Original Assignee
Hubei Zhengtong Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hubei Zhengtong Pharmaceutical Co Ltd filed Critical Hubei Zhengtong Pharmaceutical Co Ltd
Priority to CN201911134835.5A priority Critical patent/CN110787677A/en
Publication of CN110787677A publication Critical patent/CN110787677A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/11Stirrers characterised by the configuration of the stirrers
    • B01F27/112Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/90Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms 
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/10Maintenance of mixers
    • B01F35/12Maintenance of mixers using mechanical means
    • B01F35/123Maintenance of mixers using mechanical means using scrapers for cleaning mixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50Mixing receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75Discharge mechanisms
    • B01F35/754Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75455Discharge mechanisms characterised by the means for discharging the components from the mixer using a rotary discharge means, e.g. a screw beneath the receptacle
    • B01F35/754551Discharge mechanisms characterised by the means for discharging the components from the mixer using a rotary discharge means, e.g. a screw beneath the receptacle using helical screws
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

Abstract

The invention discloses a reaction kettle for bio-pharmaceuticals, which comprises a kettle body, wherein a circular hole is formed in the outer wall of the top of the kettle body, a feed hopper is arranged in the circular hole, a first protective shell is arranged on the outer wall of the top of the kettle body, a first motor is arranged on the inner wall of the top of the first protective shell, an installation plate is arranged on the outer wall of one end of an output shaft of the first motor, a fixed pipe is arranged on the installation plate, a second protective shell is arranged on the outer wall of one side of the fixed pipe, a second motor is arranged on the inner wall of one side of the second protective shell, and a stirring rod is arranged on the outer wall of. According to the invention, a worker respectively starts the first motor and the second motor, the first motor drives the stirring rod and the connecting rod to perform transverse stirring, and meanwhile, the stirring rod and the connecting rod can be driven to perform longitudinal stirring through the meshing between the driving gear and the driven gear plate, so that materials can be fully mixed, and the product quality is improved.

Description

Reation kettle for bio-pharmaceuticals
Technical Field
The invention relates to the technical field of biological pharmacy, in particular to a reaction kettle for biological pharmacy.
Background
At present, the reaction kettle is widely applied to petroleum, chemical engineering, rubber, pesticides, dyes, medicines and foods, and is a pressure container for completing processes such as vulcanization, nitration, hydrogenation, alkylation, polymerization, condensation and the like, such as a reactor, a reaction kettle, a decomposition kettle, a polymerization kettle and the like; the material is carbon manganese steel, stainless steel, zirconium, nickel-based alloy and other composite materials. The general understanding of the reaction kettle is that a stainless steel container with physical or chemical reaction is subjected to structural design and parameter configuration according to different process condition requirements, and the design conditions, the process, the inspection, the manufacture and the acceptance are required to be based on related technical standards so as to realize the heating, evaporation, cooling and low-speed mixing reaction functions required by the process.
The reaction kettle for the prior bio-pharmaceuticals has the advantages that the inner wall of the reaction kettle is easily contaminated with pharmaceutical raw materials in the working process, and the inner wall of the reaction kettle is easily caked along with the long-term use of the reaction kettle, so that the working efficiency of the reaction kettle is influenced, and the pharmaceutical raw materials are not uniformly mixed. Therefore, a reaction kettle for bio-pharmaceuticals is needed to solve the above problems.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a reaction kettle for bio-pharmaceuticals.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a reation kettle for bio-pharmaceuticals, includes the cauldron body, the top outer wall of the cauldron body is opened there is the round hole, and is provided with the feeder hopper in the round hole, the top outer wall of the cauldron body is provided with first protective housing, and the top inner wall of first protective housing is provided with first motor, the one end outer wall of first motor output shaft is provided with the mounting panel, and the mounting panel is provided with fixed pipe, one side outer wall of fixed pipe is provided with the second protective housing, and one side inner wall of second protective housing is provided with the second motor, the one end outer wall of second motor output shaft is provided with the puddler, and the circumference outer wall of puddler has cup jointed the initiative gear dish, one side outer wall meshing of initiative gear dish has driven gear dish.
As a further scheme of the invention, the outer walls of the two sides of the stirring rod are respectively provided with connecting rods which are distributed at equal intervals, the outer wall of one end of the stirring rod is rotatably connected with a scraping plate, and the outer wall of one side of the scraping plate is contacted with the inner wall of one side of the kettle body.
As a further scheme of the invention, a blanking pipe is inserted into the inner wall of the bottom of the kettle body, and fixed rods are arranged on the inner walls of two sides of the blanking pipe.
As a further scheme of the invention, the outer wall of the bottom of the fixed pipe is provided with a fixed disc, the outer wall of the bottom of the fixed disc is provided with a spiral discharging paddle, the outer wall of one end of the spiral discharging paddle is rotatably connected with a bearing seat, and the bearing seat is connected to the outer wall of the top of the fixed rod through a bolt.
As a further scheme of the invention, the outer wall of one side of the kettle body is provided with a sampling cylinder, the inner wall of the top of the sampling cylinder is inserted with a pull rod, and the outer wall of one end of the pull rod is provided with a piston.
As a further scheme of the invention, the outer wall of the bottom of the sampling tube is respectively inserted with the sampling tube and the connecting tube, the outer walls of one sides of the sampling tube and the connecting tube are respectively connected with the first control valve and the second control valve through bolts, and one end of the sampling tube, which is far away from the sampling tube, extends into the kettle body.
The invention has the beneficial effects that:
1. through the arrangement of the first motor, the second motor, the stirring rod and the connecting rod, a worker respectively starts the first motor and the second motor, the first motor drives the stirring rod and the connecting rod to perform transverse stirring, and meanwhile, the stirring rod and the connecting rod can be driven to perform longitudinal stirring through meshing between the driving gear and the driven gear disc, so that materials can be fully mixed, and the quality of a product is improved;
2. through the arranged spiral discharging paddle, the scraper plate, the discharging pipe and the fixed rod, when the fixed pipe rotates, the spiral discharging paddle is driven to rotate, at the moment, the materials in the kettle body can be discharged through the discharging pipe by the spiral discharging paddle, discharging work of people is facilitated, the discharging pipe is prevented from being blocked, meanwhile, the materials adhered to the inner wall of the kettle body can be scraped off through the scraper plate, so that not only is cleaning of workers facilitated, but also waste of resources is avoided;
3. through sampler barrel, sampling tube and the piston that sets up, people twitch the piston and can be with the internal material suction of cauldron to the sampler barrel, close first valve afterwards and open the second valve and extrude the material through the connecting pipe, made things convenient for people's sample work, the while sample process can not lead to the fact the pollution to the internal material of cauldron.
Drawings
FIG. 1 is a schematic view of a reaction vessel for biopharmaceuticals as set forth in example 1;
FIG. 2 is a schematic view showing the overall structure of a reaction vessel for biopharmaceuticals as set forth in example 1;
FIG. 3 is a schematic sectional view of the reaction vessel for biopharmaceuticals in example 2.
In the figure: 1 cauldron body, 2 fixed tubes, 3 first protecting casings, 4 feeder hoppers, 5 connecting rods, 6 scrapers, 7 puddlers, 8 spiral unloading paddles, 9 dead levers, 10 unloading pipes, 11 fixed disks, 12 second protecting casings, 13 initiative toothed disc, 14 driven toothed disc, 15 sampling barrels, 16 pistons, 17 connecting pipes, 18 sampling tubes.
Detailed Description
The technical solution of the present patent will be described in further detail with reference to the following embodiments.
Reference will now be made in detail to embodiments of the present patent, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present patent and are not to be construed as limiting the present patent.
In the description of this patent, it is to be understood that the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientations and positional relationships indicated in the drawings for the convenience of describing the patent and for the simplicity of description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the patent.
In the description of this patent, it is noted that unless otherwise specifically stated or limited, the terms "mounted," "connected," and "disposed" are to be construed broadly and can include, for example, fixedly connected, disposed, detachably connected, disposed, or integrally connected and disposed. The specific meaning of the above terms in this patent may be understood by those of ordinary skill in the art as appropriate.
Example 1
Referring to fig. 1-2, a reation kettle for bio-pharmaceuticals, including the cauldron body 1, the top outer wall of the cauldron body 1 is opened there is the round hole, and the welding has feeder hopper 4 in the round hole, the top outer wall of the cauldron body 1 has first protective housing 3 through bolted connection, and the top inner wall of first protective housing 3 has first motor through bolted connection, the one end outer wall welding of first motor output shaft has the mounting panel, and the mounting panel has fixed pipe 2 through bolted connection, one side outer wall of fixed pipe 2 has second protective housing 12 through bolted connection, and one side inner wall of second protective housing 12 has the second motor through bolted connection, the one end outer wall welding of second motor output shaft has puddler 7, and the circumference outer wall of puddler 7 has cup jointed initiative toothed disc 13, one side outer wall meshing of initiative toothed disc 13 has driven toothed disc 14.
Wherein, the connecting rod 5 that the equidistance distributes is all welded to the both sides outer wall of puddler 7, and the one end outer wall of puddler 7 rotates and is connected with scraper blade 6, one side outer wall of scraper blade 6 contacts with one side inner wall of the cauldron body 1, the bottom inner wall of the cauldron body 1 is pegged graft and is had unloading pipe 10, and the both sides inner wall of unloading pipe 10 all welds dead lever 9, the bottom outer wall welding of fixed pipe 2 has fixed disk 11, and the bottom outer wall welding of fixed disk 11 has spiral unloading oar 8, the one end outer wall rotation of spiral unloading oar 8 is connected with the bearing frame, the bearing frame passes through bolted connection on the top outer wall of dead lever 9.
The working principle is as follows: during the use, people add the material to the cauldron body 1 in through inlet pipe 4, the staff starts first motor and second motor respectively, first motor drives puddler 7 and connecting rod 5 and carries out horizontal stirring, can drive puddler 7 and connecting rod 5 through meshing between driving gear 13 and the driven gear dish 14 and vertically stir simultaneously, can make the material intensive mixing, the quality of product has been improved, when first motor drives fixed pipe 2 and rotates, fixed pipe 2 drives spiral unloading oar 8 and rotates, spiral unloading oar 8 can be discharged the material in the cauldron body 1 through unloading pipe 10 this moment, the work of unloading of people has been made things convenient for, avoid unloading pipe 10 to produce the jam, can scrape the material of adhesion at cauldron body 1 inner wall through scraper blade 6 simultaneously, not only make things convenient for staff's cleanness, the waste of resource has still been avoided.
Example 2
Referring to fig. 3, a reation kettle for bio-pharmaceuticals, this embodiment compares in embodiment 1, there is sampler barrel 15 one side outer wall of the cauldron body 1 through bolted connection, and the top inner wall of sampler barrel 15 is pegged graft and is had the pull pole, the one end outer wall of pull pole is provided with piston 16, it has sampling tube 18 and connecting pipe 17 to peg graft respectively to the bottom outer wall of sampler barrel 15, and one side outer wall of sampling tube 18 and connecting pipe 17 is connected with first control valve and second control valve respectively through the bolt, the one end that sampler barrel 15 was kept away from to sampling tube 18 extends to the cauldron body 1 inside.
The working principle is as follows: when the device is used, materials are added into the kettle body 1 through the feeding pipe 4, a worker respectively starts the first motor and the second motor, the first motor drives the stirring rod 7 and the connecting rod 5 to perform transverse stirring, and simultaneously the stirring rod 7 and the connecting rod 5 can be driven to perform longitudinal stirring through meshing between the driving gear 13 and the driven gear disc 14, so that the materials can be fully mixed, the quality of a product is improved, when the first motor drives the fixed pipe 2 to rotate, the fixed pipe 2 drives the spiral discharging paddle 8 to rotate, at the moment, the spiral discharging paddle 8 can discharge the materials in the kettle body 1 through the discharging pipe 10, the discharging work of people is facilitated, the discharging pipe 10 is prevented from being blocked, meanwhile, the materials adhered to the inner wall of the kettle body 1 can be scraped off through the scraping plate 6, the cleaning of the worker is not only facilitated, the waste of resources is also avoided, and in the process of biological pharmacy, people twitch piston 16 can be with the material suction in the cauldron body 1 to sampler barrel 15, closes first valve afterwards and opens the second valve and extrude the material through connecting pipe 17, has made things convenient for people's sample work, and the material of the while sample process in to the cauldron body 1 can not cause the pollution.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (6)

1. A reaction kettle for bio-pharmaceuticals comprises a kettle body (1) and is characterized in that the outer wall of the top of the kettle body (1) is provided with a round hole, a feed hopper (4) is arranged in the round hole, a first protective shell (3) is arranged on the outer wall of the top of the kettle body (1), and the inner wall of the top part of the first protective shell (3) is provided with a first motor, the outer wall of one end of the output shaft of the first motor is provided with a mounting plate, and the mounting plate is provided with a fixed pipe (2), the outer wall of one side of the fixed pipe (2) is provided with a second protective shell (12), a second motor is arranged on the inner wall of one side of the second protective shell (12), a stirring rod (7) is arranged on the outer wall of one end of an output shaft of the second motor, and the outer wall of the circumference of the stirring rod (7) is sleeved with a driving gear disc (13), and the outer wall of one side of the driving gear disc (13) is engaged with a driven gear disc (14).
2. The reaction kettle for the bio-pharmaceuticals according to claim 1, wherein the outer walls of the two sides of the stirring rod (7) are provided with connecting rods (5) which are distributed equidistantly, the outer wall of one end of the stirring rod (7) is rotatably connected with a scraper (6), and the outer wall of one side of the scraper (6) is in contact with the inner wall of one side of the kettle body (1).
3. The reaction kettle for bio-pharmaceuticals according to claim 2, wherein a discharging pipe (10) is inserted into the inner wall of the bottom of the kettle body (1), and fixing rods (9) are arranged on the inner walls of two sides of the discharging pipe (10).
4. The reaction kettle for bio-pharmaceuticals according to claim 3, wherein the outer wall of the bottom of the fixed tube (2) is provided with a fixed plate (11), the outer wall of the bottom of the fixed plate (11) is provided with a spiral discharging paddle (8), the outer wall of one end of the spiral discharging paddle (8) is rotatably connected with a bearing seat, and the bearing seat is connected to the outer wall of the top of the fixed rod (9) through a bolt.
5. The reaction kettle for bio-pharmaceuticals according to claim 3 or 4, wherein the outer wall of one side of the kettle body (1) is provided with a sampling cylinder (15), the inner wall of the top of the sampling cylinder (15) is inserted with a pull rod, and the outer wall of one end of the pull rod is provided with a piston (16).
6. The reaction kettle for bio-pharmaceuticals according to claim 5, wherein the sampling tube (18) and the connecting tube (17) are respectively inserted into the outer wall of the bottom of the sampling tube (15), the outer walls of one side of the sampling tube (18) and one side of the connecting tube (17) are respectively connected with the first control valve and the second control valve through bolts, and one end of the sampling tube (18) far away from the sampling tube (15) extends into the kettle body (1).
CN201911134835.5A 2019-11-19 2019-11-19 Reation kettle for bio-pharmaceuticals Pending CN110787677A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911134835.5A CN110787677A (en) 2019-11-19 2019-11-19 Reation kettle for bio-pharmaceuticals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911134835.5A CN110787677A (en) 2019-11-19 2019-11-19 Reation kettle for bio-pharmaceuticals

Publications (1)

Publication Number Publication Date
CN110787677A true CN110787677A (en) 2020-02-14

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Country Link
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111921481A (en) * 2020-09-10 2020-11-13 合肥谷口化工科技有限公司 Synthesis process of water-based acrylic emulsion
CN112058198A (en) * 2020-08-18 2020-12-11 常熟市天工医药化工设备有限公司 A reation kettle for pharmaceutical production
CN112871119A (en) * 2021-02-02 2021-06-01 北京图腾猎技科技有限公司 Antibiotic composition biosynthesis equipment

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112058198A (en) * 2020-08-18 2020-12-11 常熟市天工医药化工设备有限公司 A reation kettle for pharmaceutical production
CN111921481A (en) * 2020-09-10 2020-11-13 合肥谷口化工科技有限公司 Synthesis process of water-based acrylic emulsion
CN112871119A (en) * 2021-02-02 2021-06-01 北京图腾猎技科技有限公司 Antibiotic composition biosynthesis equipment

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Application publication date: 20200214

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