CN110779766B - Body fluid pipeline sampling method - Google Patents

Body fluid pipeline sampling method Download PDF

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Publication number
CN110779766B
CN110779766B CN201911075108.6A CN201911075108A CN110779766B CN 110779766 B CN110779766 B CN 110779766B CN 201911075108 A CN201911075108 A CN 201911075108A CN 110779766 B CN110779766 B CN 110779766B
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China
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body fluid
fluid pipeline
pipeline
clamping
puncture needle
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CN201911075108.6A
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CN110779766A (en
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甘特·梅埃尔霍夫
罗伯特·科佩茨基
何俊
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Wuhan Baikehongcheng Biotechnology Co ltd
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Wuhan Baikehongcheng Biotechnology Co ltd
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Priority to PCT/CN2019/129909 priority patent/WO2021088237A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state

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  • Life Sciences & Earth Sciences (AREA)
  • Hydrology & Water Resources (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention discloses a body fluid pipeline sampling method, which comprises the following steps: s1, making openings at two ends of the body fluid pipeline, S2, injecting air into the body fluid pipeline from the opening at one end of the body fluid pipeline, and S3, enabling the liquid to be taken out to flow out from the other end of the body fluid pipeline; the scheme is that the two ends of the body fluid pipeline are punctured when the supporting body is assembled with the body fluid pipeline fixing part, air is blown in to discharge liquid, and the operation is very simple and convenient; the liquid leakage can not occur.

Description

Body fluid pipeline sampling method
Technical Field
The invention relates to the technical field of blood component subpackaging, in particular to a body fluid pipeline sampling method.
Background
In recent years, a method for bioremediation therapy to severe xerophthalmia by extracting autologous serum from whole blood has appeared. The autologous serum contains auto-rich active polypeptide micromolecule repair factors and adhesive proteins, can effectively activate the re-secretion of lacrimal glands, repair the functions of the lacrimal glands, greatly relieve the symptoms of the xerophthalmia, redness of the eyes, foreign body sensation in the eyes and dry sensation in the eyes, and achieve the aim of relieving and curing the xerophthalmia. Meanwhile, the self-serum is applied, so that the eye-care product has no rejection, no anaphylactic reaction, no toxic or side effect and 100 percent safety, and is a new biological therapy for treating the eye dryness with the morbidity of more than 20 percent.
When the autologous serum is produced, the autologous serum is packaged in a tiny segmented blood bag catheter, the autologous serum in the pipeline is used for one time, and the autologous serum in the pipeline needs to be taken out during use.
However, since the reagent itself is thin, the method conventionally used is to cut one end of the body fluid tube, but there are the following problems: the autologous serum is easy to overflow after being cut, which causes the waste of the autologous serum.
Disclosure of Invention
The present invention is directed to solving the above problems by providing a method for sampling a body fluid line.
The technical scheme adopted by the invention is as follows: a method of sampling a bodily fluid conduit, comprising the steps of: s1, simultaneously making openings at two ends of the body fluid pipeline, S2, injecting air into the body fluid pipeline from the opening at one end of the body fluid pipeline, and S3, enabling the liquid to be taken out to flow out from the other end of the body fluid pipeline.
The invention has the following effects: the scheme is that the two ends of the body fluid pipeline are punctured when the supporting body is assembled with the body fluid pipeline fixing part, air is blown in to discharge liquid, and the operation is very simple and convenient; the liquid leakage can not occur.
Drawings
FIG. 1 is a schematic diagram illustrating the steps of a method for sampling a bodily fluid line according to the present invention;
FIG. 2 is a schematic structural view of a U-shaped liquid extractor according to the present invention;
FIG. 3 is a schematic view of an exploded structure of a U-shaped liquid extractor according to the present invention;
figure 4 is a cross-sectional view of the carrier of figure 2;
fig. 5 is a schematic structural view of the body fluid conduit fixing part in fig. 2.
Detailed Description
The body fluid pipeline sampling method of the invention is described below with reference to the accompanying drawings:
as shown in FIG. 1, the invention provides a sampling method of a body fluid pipeline, which comprises the following steps:
s1, simultaneously making openings at both ends of the body fluid conduit,
s2, injecting air into the body fluid pipeline from the opening at one end of the body fluid pipeline,
and S3, the liquid to be taken out flows out from the other end of the body fluid pipeline.
In this embodiment, the step S1 includes the following steps:
s11, pulling the push rod to enable the part of the push rod, which is positioned outside the gas injection area, to reach the maximum state;
s12, fixing two ends of the body fluid pipeline to be extracted to the body fluid pipeline fixing parts respectively;
s13, the body fluid pipeline fixing part is clamped with the bearing body, and the two ends of the body fluid pipeline are punctured by the puncture needle in the bearing body.
In this embodiment, the step S12 includes the following steps:
s121, one end of a body fluid pipeline to be subjected to fluid extraction extends into the first clamping end, and the first clamping end clamps the end of the body fluid pipeline;
and S122, the other end of the body fluid pipeline to be subjected to fluid extraction extends into the second clamping end, and the second clamping end clamps the end part of the body fluid pipeline.
In this embodiment, the step S13 includes the following steps:
s131, aligning a first convex strip on the first clamping plate with a first guide groove on the first fixing plate, and aligning a second convex strip on the second clamping plate with a second guide groove on the second fixing plate;
s132, pushing the body fluid pipeline fixing part to enable the first convex strip on the first clamping plate to gradually slide into the first guide groove on the first fixing plate and the second convex strip on the second clamping plate to gradually slide into the second guide groove on the second fixing plate;
s133, the first clamping block is clamped with the end part of the first fixing plate, and the second clamping block is clamped with the end part of the second fixing plate; the first clamping end extends into the first pipeline, and the second clamping end extends into the second pipeline;
s134, one end of the body fluid pipeline is punctured by the first puncture needle in the first pipeline, and the other end of the body fluid pipeline is punctured by the second puncture needle in the second pipeline.
In this embodiment, the step S2 includes the following steps:
s21, pushing the push rod to make the air in the air injection area input into the body fluid pipeline from the first puncture needle.
In this embodiment, the step S3 includes the following steps:
s31, discharging the liquid in the body fluid pipeline from one end of the body fluid pipeline punctured by the second puncture needle by the input air;
s32, the liquid in the body fluid pipeline is discharged into the liquid discharge area from the second puncture needle and finally discharged to the outside from the U-shaped liquid extractor.
For the convenience of understanding, the invention also provides a U-shaped liquid extractor.
As shown in fig. 2-5, the U-shaped liquid extractor provided by the present invention comprises a supporting body 1, a body fluid duct fixing portion 2 and a boosting portion 3, wherein the body fluid duct fixing portion 2 is clamped with the supporting body 1, and the boosting portion 3 is movably connected with the supporting body 1.
The supporting body 1 comprises a first straight cylinder part 11, a second straight cylinder part 12 and a fixing part 13 fixed between the first straight cylinder part 11 and the second straight cylinder part 12, one end of the first straight cylinder part 11 and one end of the second straight cylinder part 12 are clamped with the body fluid pipeline fixing part 2, and the boosting part 3 is movably connected with the other end of the first straight cylinder part 11.
The first straight cylinder part 11 comprises a first pipeline 111, a first clapboard 112 and a first puncture needle 113, the first clapboard 112 is arranged in the first pipeline 111 to divide the first pipeline 111 into an air injection area 114 and a first puncture area 115, the first puncture needle 113 is fixed on the first clapboard 112, the first puncture needle 113 faces the first puncture area 115, and a pipeline inside the first puncture needle 113 is communicated with the air injection area 114.
The second straight cylinder part 12 comprises a second pipeline 121, a second partition plate 122 and a second puncture needle 123, the second partition plate 122 is arranged in the second pipeline 121 to divide the second pipeline 121 into a liquid discharge region 124 and a second puncture region 125, the second puncture needle 113 is fixed on the second partition plate 122, the second puncture needle 123 faces the second puncture region 125, and a pipeline in the second puncture needle 123 is communicated with the liquid discharge region 124.
The fixing portion 13 includes a first fixing plate 131 and a second fixing plate 132, a side of the first fixing plate 131 is fixed to the first straight tube portion 11 and the second straight tube portion 12, a side of the second fixing plate 132 is fixed to the first straight tube portion 11 and the second straight tube portion 12, and a clamping space is formed between the first fixing plate 131 and the second fixing plate 132.
A first guide groove 133 is formed on a surface of the first fixing plate 131 facing the second fixing plate 132, and a second guide groove 134 is formed on a surface of the second fixing plate 132 facing the first fixing plate 131.
The body fluid pipeline fixing part 2 comprises a first clamping end 21, a second clamping end 22, a first clamping plate 23 and a second clamping plate 24, two side edges of the first clamping plate 23 are respectively fixed with the first clamping end 21 and the second clamping end 22, and two side edges of the second clamping plate 24 are respectively fixed with the first clamping end 21 and the second clamping end 22.
The first holding end 21 is matched with the first piercing region 115, and the diameter of the first holding end 21 is gradually reduced along the axial direction. Thereby, the end of the blood tube containing the blood component can be fixed.
The second holding end 22 is matched with the second puncturing area 125, and the diameter of the second holding end 22 is gradually reduced along the axial direction. Thereby, the other end of the blood tube containing the blood component can be fixed.
The surface of the first clamping plate 23 away from the second clamping plate 24 is provided with a first protruding strip 231 matched with the first guide groove 133, and the end of the first clamping plate 23 is provided with a first clamping block 232.
A second protruding strip 241 matched with the second guide groove 134 is formed on the surface, away from the first clamping plate 23, of the second clamping plate 24, and a second clamping block 242 is arranged at the end of the second clamping plate 24.
Body fluid pipeline fixed part 2 with during 1 joint of supporting body, first exposed core 21 stretches into in the first region 115 of punctureing, second exposed core 22 stretches into in the second region 125 of punctureing, first sand grip 231 inlays to be established in the first guide way 133, second sand grip 241 inlays to be established in the second guide way 134, first joint piece 232 second joint piece 242 respectively with the tip of first fixed plate 131 reaches the tip of second fixed plate 132 forms the joint.
The boosting section 3 includes a push rod 31 and a piston head 32, the piston head 32 is disposed on one end of the push rod 31, and the piston head 32 extends into the gas injection region 114.
The piston head 32 is slidable within the gas injection region 114. When the portion of the push rod 31 located outside the gas injection area 114 reaches the maximum state, the gas injection area 114 is filled with air.
When the U-shaped liquid extractor is used, the push rod 31 is pulled firstly, so that the part of the push rod 31, which is positioned outside the gas injection area 114, reaches the maximum state, then the two ends of the body fluid pipeline 4 which is filled with liquid to be extracted are fixed by the first clamping end 21 and the second clamping end 22 respectively, then the body fluid pipeline fixing part 2 is clamped with the supporting body 1, in the clamping process, the first puncture needle 113 and the second puncture needle 123 respectively puncture the two ends of the body fluid pipeline 4, at the moment, the push rod 31 is pushed, so that the push rod 31 enables gas in the gas injection area 114 to be input into the body fluid pipeline 4, and blood components in the body fluid pipeline 4 are discharged from the liquid discharge area 124.
Advantageous effects
The scheme is that the two ends of the body fluid pipeline are punctured when the supporting body is assembled with the body fluid pipeline fixing part, air is blown in to discharge liquid, and the operation is very simple and convenient; the liquid leakage can not occur.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (3)

1. A method for sampling a bodily fluid conduit, comprising the steps of:
s1, simultaneously making openings at both ends of the body fluid conduit,
s2, injecting air into the body fluid pipeline from the opening at one end of the body fluid pipeline,
s3, the liquid to be taken out flows out from the other end of the body fluid pipeline;
wherein the step S1 includes the steps of:
s11, pulling the push rod to enable the part of the push rod, which is positioned outside the gas injection area, to reach the maximum state;
s12, fixing two ends of the body fluid pipeline to be extracted to the body fluid pipeline fixing parts respectively;
s13, clamping the body fluid pipeline fixing part with the bearing body, and puncturing the two ends of the body fluid pipeline by the puncture needle in the bearing body;
the step S2 includes the steps of:
s21, pushing the push rod to input the air in the air injection area into the body fluid pipeline from the first puncture needle;
the step S3 includes the steps of:
s31, discharging the liquid in the body fluid pipeline from one end of the body fluid pipeline punctured by the second puncture needle by the input air;
s32, the liquid in the body fluid pipeline is discharged into the liquid discharge area from the second puncture needle and finally discharged to the outside from the U-shaped liquid extractor.
2. The method for sampling a bodily fluid duct according to claim 1, characterized in that the step S12 includes the steps of:
s121, one end of a body fluid pipeline to be extracted extends into a first clamping end, and the first clamping end clamps the end of the body fluid pipeline;
s122, the other end of the body fluid pipeline to be extracted extends into a second clamping end, and the second clamping end clamps the end of the body fluid pipeline.
3. The method for sampling a bodily fluid duct according to claim 2, characterized in that the step S13 includes the steps of:
s131, aligning a first convex strip on the first clamping plate with a first guide groove on the first fixing plate, and aligning a second convex strip on the second clamping plate with a second guide groove on the second fixing plate;
s132, pushing the body fluid pipeline fixing part to enable the first convex strip on the first clamping plate to gradually slide into the first guide groove on the first fixing plate and the second convex strip on the second clamping plate to gradually slide into the second guide groove on the second fixing plate;
s133, the first clamping block is clamped with the end part of the first fixing plate, and the second clamping block is clamped with the end part of the second fixing plate; the first clamping end extends into the first pipeline, and the second clamping end extends into the second pipeline;
s134, one end of the body fluid pipeline is punctured by the first puncture needle in the first pipeline, and the other end of the body fluid pipeline is punctured by the second puncture needle in the second pipeline.
CN201911075108.6A 2019-11-05 2019-11-05 Body fluid pipeline sampling method Active CN110779766B (en)

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Application Number Priority Date Filing Date Title
CN201911075108.6A CN110779766B (en) 2019-11-05 2019-11-05 Body fluid pipeline sampling method
PCT/CN2019/129909 WO2021088237A1 (en) 2019-11-05 2019-12-30 Body fluid pipeline sampling method

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Application Number Priority Date Filing Date Title
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CN110779766B true CN110779766B (en) 2021-03-26

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Citations (3)

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JP2005233764A (en) * 2004-02-19 2005-09-02 Ids:Kk Drilling machine for dispensing
CN101044387A (en) * 2004-03-15 2007-09-26 美国血液技术公司 Closed method and system for the sampling and testing of fluid

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CN2344776Y (en) * 1998-12-03 1999-10-20 张朝霞 Disposable humor sampler
CN200977160Y (en) * 2006-06-26 2007-11-21 邓冠华 Vacuum blood taking test tube
JP5322790B2 (en) * 2009-06-15 2013-10-23 川澄化学工業株式会社 Blood component sampling system, blood component sampling method, and blood collection tube
CN202141606U (en) * 2011-07-28 2012-02-08 重庆密奥仪器有限公司 Acupuncture sampler
CN203824799U (en) * 2014-05-13 2014-09-10 江苏爵格工业设备有限公司 Airtight sampling device
CN205774523U (en) * 2016-05-24 2016-12-07 北京海乐思医学检验所有限公司 One utilizes plasma DNA to cancer verifying attachment
CN106226129A (en) * 2016-07-06 2016-12-14 江苏科华医疗器械科技有限公司 A kind of closed type urine sampler
CN206192750U (en) * 2016-11-23 2017-05-24 山东美医林电子仪器有限公司 Sampling needle
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2349484A1 (en) * 1971-01-12 1974-08-22 Damon Corp Blood sample container - with storage compartment of specified cross sections has suction pipe attachment
JP2005233764A (en) * 2004-02-19 2005-09-02 Ids:Kk Drilling machine for dispensing
CN101044387A (en) * 2004-03-15 2007-09-26 美国血液技术公司 Closed method and system for the sampling and testing of fluid

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CN110779766A (en) 2020-02-11

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