CN110755462A - External spray for treating gastrocnemius spasm and preparation method thereof - Google Patents
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Abstract
The invention discloses an external spray for treating gastrocnemius spasm and a preparation method thereof, and aims to solve the problem that the existing external spray for treating gastrocnemius spasm is blank. The invention comprises the following raw materials in parts by weight: 1.5-2.5 parts of pseudo-ginseng extract, 1-3 parts of lycopodium clavatum extract, 1.5-4.5 parts of borneol, 0.05-0.15 part of menthol, 0.03-0.29 part of chlorhexidine acetate, 0.5-1.5 parts of marsdenia tenacissima extract, 66-75 parts of edible alcohol and 25-33 parts of purified water. After the product is used, the content of lactic acid in the blood of gastrocnemius is reduced, the muscle contraction is relieved, so the pain is relieved immediately, after the product is frequently used, the muscle blood vessel is softened more and more, the attack times are reduced less and less, the healing is finally achieved, and the product has originality, advancement and popularization.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to an external spray for treating gastrocnemius spasm.
Background
Gastrocnemius spasm, i.e. "cramp" is the most common one of cramps, and is characterized by sudden onset of gastrocnemius, spasms with spasms of spasticity with rigidity and pain such as torsion, which is difficult to be famous. Especially, when cramps in the middle of the night, people are often waken up, and can not relieve pain for a long time, namely a few minutes, and 1-2 hours for the long people, so that sleep is seriously affected, and especially the old people can be threatened. The morbidity of gastrocnemius spasm is improved, and the morbidity of the old aged over 65 years old is counted to be over 80. Seriously threatens the health of people and is a frequently encountered disease.
At present, the treatment methods aiming at gastrocnemius spasm include oral medicine, acupuncture treatment, physical therapy, massage and the like, but external medicines in the aspect are not available.
Disclosure of Invention
The invention aims to provide an external spray for treating gastrocnemius spasm, which is used for solving the problems in the background technology.
In order to achieve the above purpose, the embodiments of the present invention provide the following technical solutions:
an external spray for treating gastrocnemius spasm comprises the following raw materials in parts by weight: 1.5-2.5 parts of pseudo-ginseng extract, 1-3 parts of lycopodium clavatum extract, 1.5-4.5 parts of borneol, 0.05-0.15 part of menthol, 0.03-0.29 part of chlorhexidine acetate, 0.5-1.5 parts of marsdenia tenacissima extract, 66-75 parts of edible alcohol and 25-33 parts of purified water.
As a further scheme of the embodiment of the invention: the Notoginseng radix extract is prepared from Notoginseng radix by decocting, percolating, refluxing, distilling, precipitating, standing, filtering, concentrating, and drying.
As a further scheme of the embodiment of the invention: the herba Lycopodii extract is prepared from herba Lycopodii by pulverizing, extracting, concentrating, purifying and drying.
As a further scheme of the embodiment of the invention: the marsdenia tenacissima extract is prepared by the processes of elutriating, drying, crushing, extracting, concentrating, precipitating, extracting, crystallizing, adsorbing, resolving and drying marsdenia tenacissima.
The preparation method of the external spray for treating gastrocnemius spasm comprises the following specific steps:
step one, adding borneol and menthol into edible alcohol according to a ratio, and stirring for 25-38 minutes until the borneol and the menthol are completely dissolved to obtain a first mixture;
step two, adding the panax notoginseng extract, the lycopodium clavatum extract, the chlorhexidine acetate and the marsdenia tenacissima extract into the first mixture, stirring for 18-24 minutes, adding purified water into the mixture after the mixture is fully dissolved, stirring uniformly to obtain a finished product, and then bottling and packaging the finished product for later use.
As a further scheme of the embodiment of the invention: in the first step, the stirring temperature is 24-45 ℃.
As a further scheme of the embodiment of the invention: the stirring speed in the second step is 240-630 rpm.
Tianqi has the actions of removing blood stasis and stopping bleeding, relieving swelling and relieving pain, and is mainly used for hemoptysis, thoracico-abdominal stabbing pain and traumatic injury for external use.
Herba Lycopodii has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles and activating collaterals. Can be used for treating joint pain and difficulty in flexion and extension.
Borneol has the functions of opening the pilferage and refreshing mind, clearing away heat and toxic material, and can be used for treating high fever and coma, apoplexy with phlegm syncope and epilepsy, summer-heat and damp obstruction, etc.
Mentholum has effects of dispelling pathogenic wind, clearing heat and detoxicating. It is used externally to treat pain and cold.
Chlorhexidine acetate has antibacterial and antiseptic effects.
Tongguanteng, with actions of alleviating pain and relieving dyspnea, clearing heat and removing toxicity, is used for treating rheumatic swelling and pain, sores and abscess, etc.
The using method of the external spray for treating gastrocnemius spasm comprises the following specific steps: when the gastrocnemius spasm is painful, the product is sprayed on the skin of the calf muscle directly, and the pain is gradually relieved after 15-30 seconds, so that the use is very convenient.
Compared with the prior art, the embodiment of the invention has the beneficial effects that:
the pseudo-ginseng and the lycopodium clavatum in the product have the functions of activating blood circulation to dissipate blood stasis and activating tendons and vessels. Borneol and menthol have the functions of dispelling wind, detoxifying, stealing, relieving pain and the like, the blood circulation of calf muscles can be rapidly improved, the local blood circulation is accelerated, the microvessels in the microcirculation expand, and the accelerated blood flow takes away local harmful metabolites such as lactic acid (when gastrocnemius muscle spasm, the concentration of the lactic acid in the local blood is obviously increased, so that muscle stiffness and strong contraction are caused, and pain is caused). After the product is used, the content of lactic acid in the blood of gastrocnemius is reduced, the muscle contraction is relieved, so the pain is relieved immediately, after the product is frequently used, the muscle blood vessel is softened more and more, the attack times are reduced less and less, the healing is finally achieved, and the product has originality, advancement and popularization.
The formula of the invention is summarized by the inventor in more than 40 years of clinical work, and is widely applied in clinic, so that the invention is well received and affirmed by patients, and the invention fills up the blank at home and abroad of treating gastrocnemius spasm by external use of medicine.
Detailed Description
The technical solution of the present patent will be described in further detail with reference to the following embodiments.
Example 1
An external spray for treating gastrocnemius spasm comprises the following raw materials: 1.5 kg of pseudo-ginseng extract, 1 kg of lycopodium clavatum extract, 1.5 kg of borneol, 0.05 kg of menthol, 0.03 kg of chlorhexidine acetate, 0.5 kg of marsdenia tenacissima extract, 66 kg of edible alcohol and 25 kg of purified water. The Notoginseng radix extract is prepared from Notoginseng radix by decocting, percolating, refluxing, distilling, precipitating, standing, filtering, concentrating, and drying. The marsdenia tenacissima extract is prepared by the processes of elutriating, drying, crushing, extracting, concentrating, precipitating, extracting, crystallizing, adsorbing, resolving and drying marsdenia tenacissima.
The preparation method of the external spray for treating gastrocnemius spasm comprises the following specific steps:
step one, adding borneol and menthol into edible alcohol according to a ratio, and stirring for 25 minutes until the borneol and the menthol are completely dissolved to obtain a first mixture;
step two, adding the pseudo-ginseng extract, the lycopodium clavatum extract, the chlorhexidine acetate and the marsdenia tenacissima extract into the first mixture, stirring for 22 minutes, adding purified water into the mixture after the mixture is fully dissolved, stirring uniformly to obtain a finished product, and then bottling and packaging for later use.
Example 2
An external spray for treating gastrocnemius spasm comprises the following raw materials: 1.89 kg of panax notoginseng extract, 1.93 kg of lycopodium clavatum extract, 2.37 kg of borneol, 0.08 kg of menthol, 0.11 kg of chlorhexidine acetate, 0.96 kg of marsdenia tenacissima extract, 68.7 kg of edible alcohol and 28.4 kg of purified water. The herba Lycopodii extract is prepared from herba Lycopodii by pulverizing, extracting, concentrating, purifying and drying. The marsdenia tenacissima extract is prepared by the processes of elutriating, drying, crushing, extracting, concentrating, precipitating, extracting, crystallizing, adsorbing, resolving and drying marsdenia tenacissima.
The preparation method of the external spray for treating gastrocnemius spasm comprises the following specific steps:
step one, adding borneol and menthol into edible alcohol according to a ratio, stirring for 33 minutes until the borneol and the menthol are completely dissolved, wherein the stirring temperature is 31 ℃, and obtaining a first mixture;
step two, adding the pseudo-ginseng extract, the lycopodium clavatum extract, the chlorhexidine acetate and the marsdenia tenacissima extract into the first mixture, stirring for 18 minutes, adding purified water into the mixture after the mixture is fully dissolved, stirring uniformly to obtain a finished product, and then bottling and packaging for later use.
Example 3
An external spray for treating gastrocnemius spasm comprises the following raw materials: 2.24 kg of pseudo-ginseng extract, 2.43 kg of lycopodium clavatum extract, 3.94 kg of borneol, 0.12 kg of menthol, 0.21 kg of chlorhexidine acetate, 1.16 kg of marsdenia tenacissima extract, 72.4 kg of edible alcohol and 30 kg of purified water. The Notoginseng radix extract is prepared from Notoginseng radix by decocting, percolating, refluxing, distilling, precipitating, standing, filtering, concentrating, and drying. The herba Lycopodii extract is prepared from herba Lycopodii by pulverizing, extracting, concentrating, purifying and drying. The marsdenia tenacissima extract is prepared by the processes of elutriating, drying, crushing, extracting, concentrating, precipitating, extracting, crystallizing, adsorbing, resolving and drying marsdenia tenacissima.
The preparation method of the external spray for treating gastrocnemius spasm comprises the following specific steps:
step one, adding borneol and menthol into edible alcohol according to a ratio, stirring for 25-38 minutes until the borneol and the menthol are completely dissolved, wherein the stirring temperature is 38 ℃, and obtaining a first mixture;
and step two, adding the panax notoginseng extract, the lycopodium clavatum extract, the chlorhexidine acetate and the marsdenia tenacissima extract into the first mixture, stirring for 20 minutes, adding purified water into the mixture after the mixture is fully dissolved, uniformly stirring the mixture at the stirring speed of 450rpm to obtain a finished product, and then bottling and packaging the finished product for later use.
Example 4
An external spray for treating gastrocnemius spasm comprises the following raw materials: 2.5 kg of pseudo-ginseng extract, 3 kg of lycopodium clavatum extract, 4.5 kg of borneol, 0.15 kg of menthol, 0.29 kg of chlorhexidine acetate, 1.5 kg of marsdenia tenacissima extract, 75 kg of edible alcohol and 33 kg of purified water.
The preparation method of the external spray for treating gastrocnemius spasm comprises the following specific steps:
step one, adding borneol and menthol into edible alcohol according to a ratio, and stirring for 36 minutes until the borneol and the menthol are completely dissolved to obtain a first mixture;
step two, adding the pseudo-ginseng extract, the lycopodium clavatum extract, the chlorhexidine acetate and the marsdenia tenacissima extract into the first mixture, stirring for 24 minutes, adding purified water into the mixture after the mixture is fully dissolved, stirring uniformly to obtain a finished product, and then bottling and packaging for later use.
The action mechanism of the product is the changed movement mode of the muscle, when gastrocnemius is spasmodic, the muscle is in tonic contraction, and the movement mode of the muscle is anaerobic glycolysis. The oxygen intake during anaerobic glycolysis is very low. Because of the too fast muscle movement speed and the too violent explosive force, sugar in the human body has no time to be decomposed by oxygen and has to be supplied by oxygen-free energy. The exercise can generate excessive lactic acid and some harmful substances in the body, so that muscle fatigue cannot last, muscle ache is felt after muscle contraction, and the breath is rapid. In fact, when anaerobic glycolysis is carried out, a large amount of intermediate metabolic products such as pyruvic acid, lactic acid and the like can be generated and cannot be eliminated through respiration, and the acidic products are accumulated in cells and blood to form fatigue toxin, so that people feel fatigue, weakness and muscle soreness. Human muscle requires energy when contracting, and if the energy comes from aerobic metabolism (oxidation reaction) in muscle cells, aerobic exercise is performed. If the energy comes from anaerobic glycolysis, anaerobic exercise is performed. When metabolized aerobically, sufficient oxidation of one molecule of glucose can produce 38 ATP's, whereas in anaerobic glycolysis only 2 ATP's can be produced. During aerobic exercise, water and carbon dioxide are generated after glucose is metabolized, and can be easily discharged out of the body through respiration without harm to the human body, however, during anaerobic glycolysis, the body can generate a large amount of lactic acid, pyruvic acid and other intermediate products.
The essence of gastrocnemius spasm is anaerobic exercise of gastrocnemius, which results in that the exercise cannot fully utilize glucose, the muscle lacks energy, and a large amount of lactic acid and pyruvic acid are accumulated in the muscle, so that the muscle spasm is hard to endure, and the 5 traditional Chinese medicines in the product are organically combined to play a synergistic role. Notoginseng radix has effects of promoting blood circulation, stopping bleeding, and improving microcirculation, and herba Lycopodii has effects of resisting inflammation, relieving fatigue, and relieving pain. Marsdenia tenacissima has the functions of clearing away heat and toxic materials. Borneolum has effects of clearing away heat and relieving pain. The Mentholum has refreshing, antiinflammatory and qi circulation promoting effects. Under the combined action of the 5 medicines, the product accelerates the blood circulation of gastrocnemius, takes away harmful substances in blood, such as lactic acid, pyruvic acid and the like, changes anaerobic glycolysis of gastrocnemius into aerobic exercise, enables the muscle to fully utilize glucose for energy supply, and metabolites of the aerobic exercise are water and carbon dioxide which are harmless to human bodies. Thus, the combined action of the 5 medicines can quickly relieve the spasm and pain of muscles.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (7)
1. An external spray for treating gastrocnemius spasm is characterized by comprising the following raw materials in parts by weight: 1.5-2.5 parts of pseudo-ginseng extract, 1-3 parts of lycopodium clavatum extract, 1.5-4.5 parts of borneol, 0.05-0.15 part of menthol, 0.03-0.29 part of chlorhexidine acetate, 0.5-1.5 parts of marsdenia tenacissima extract, 66-75 parts of edible alcohol and 25-33 parts of purified water.
2. The external spray for treating gastrocnemius spasm according to claim 1, wherein the Panax notoginseng extract is obtained by decocting Panax notoginseng, percolating, refluxing, distilling, precipitating, standing, filtering, concentrating and drying.
3. The external spray for treating gastrocnemius spasm as claimed in claim 1 or 2, wherein the Lycopodium clavatum extract is prepared from Lycopodium clavatum by pulverizing, extracting, concentrating, purifying and drying.
4. The external spray for treating gastrocnemius spasm according to claim 1, wherein the marsdenia tenacissima extract is obtained by washing, drying, crushing, extracting, concentrating, precipitating, extracting, crystallizing, adsorbing, resolving and drying the marsdenia tenacissima.
5. A preparation method of the external spray for treating gastrocnemius spasm as claimed in any one of claims 1-4, which comprises the following specific steps:
step one, adding borneol and menthol into edible alcohol according to a ratio, and stirring for 25-38 minutes until the borneol and the menthol are completely dissolved to obtain a first mixture;
and step two, adding the panax notoginseng extract, the lycopodium clavatum extract, the chlorhexidine acetate and the marsdenia tenacissima extract into the first mixture, stirring for 18-24 minutes, adding purified water into the mixture after the mixture is fully dissolved, and stirring uniformly to obtain a finished product.
6. The method for preparing an external spray for treating gastrocnemius spasm according to claim 5, wherein the stirring temperature in the first step is 24-45 ℃.
7. The method as claimed in claim 5 or 6, wherein the stirring speed in step two is 240-630 rpm.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112569330A (en) * | 2020-11-25 | 2021-03-30 | 甘肃岷海医药科技有限公司 | Spray dressing for relieving muscle fatigue and pain caused by exercise and preparation method thereof |
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| CN101288711A (en) * | 2007-04-20 | 2008-10-22 | 江苏康缘药业股份有限公司 | Chinese medicinal composition for treating arthritic and its preparation method |
| CN104784270A (en) * | 2015-04-27 | 2015-07-22 | 王和鸣 | External preparation capable of relieving swelling and pain and preparation method thereof |
| CN104840772A (en) * | 2015-05-13 | 2015-08-19 | 王冬梅 | External patch for relieving leg systremma and preparation method |
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2019
- 2019-11-22 CN CN201911152635.2A patent/CN110755462A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097611A (en) * | 1993-07-19 | 1995-01-25 | 艾培基 | Fast acting pain clearing medicine |
| CN101288711A (en) * | 2007-04-20 | 2008-10-22 | 江苏康缘药业股份有限公司 | Chinese medicinal composition for treating arthritic and its preparation method |
| CN104784270A (en) * | 2015-04-27 | 2015-07-22 | 王和鸣 | External preparation capable of relieving swelling and pain and preparation method thereof |
| CN104840772A (en) * | 2015-05-13 | 2015-08-19 | 王冬梅 | External patch for relieving leg systremma and preparation method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112569330A (en) * | 2020-11-25 | 2021-03-30 | 甘肃岷海医药科技有限公司 | Spray dressing for relieving muscle fatigue and pain caused by exercise and preparation method thereof |
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Effective date of registration: 20200323 Address after: 334400 Jiangxi Province, Shangrao city Yiyang County Industrial Park Nanyan District Applicant after: Jiangxi Baikang Pharmaceutical Co.,Ltd. Applicant after: Zhu Shaoyi Address before: 334400 Jiangxi Province, Shangrao city Yiyang County Industrial Park Nanyan District Applicant before: Jiangxi Baikang Pharmaceutical Co.,Ltd. |
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| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200207 |